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Journal of Pharmacy Practice

Jenny H Kang, Quynh-Nhu Nguyen, Juleann Mutka, Quang A Le
No abstract text is available yet for this article.
June 2017: Journal of Pharmacy Practice
Salia Farrokh, Amber C Castle, Mojdeh Heavner, Margaret A Pisani
PURPOSE: The frequency with which atypical antipsychotics initiated in the intensive care unit (ICU) is unknown. While there is lack of evidence to support the exact duration of treatment, antipsychotics should not be continued chronically for agitation and psychosis related to critical illness. The objective of this study was to determine whether atypical antipsychotics initiated in the ICU at a large tertiary academic medical center were continued after hospital discharge. Safety outcomes were also assessed...
June 2017: Journal of Pharmacy Practice
Jillian T Dempsey, Lina S Matta, Danielle M Carter, Craig A Stevens, Lynne W Stevenson, Akshay S Desai, Judy W Cheng
BACKGROUND: The Ambulatory Cardiac Triage, Intervention, and Education (ACTIVE) infusion unit is an outpatient center that aims to provide heart failure (HF) patients with comprehensive multidisciplinary interventions. OBJECTIVE: To describe the patient population served in ACTIVE and to document the prevalence of comorbidities and drug therapy-related issues (DRIs) in order to define the most effective role of a pharmacist in the unit. METHODS: Patients who have been interviewed by a pharmacist in ACTIVE were included...
June 2017: Journal of Pharmacy Practice
Cory M Hale, Robert W Seabury, Jeffrey M Steele, William Darko, Christopher D Miller
PURPOSE: To determine whether there is an association between higher vancomycin trough concentrations and attainment of a calculated area under the concentration-time curve (AUC)/minimum inhibitory concentration (MIC) ≥400. METHODS: A retrospective analysis was conducted among vancomycin-treated adult patients with a positive methicillin-resistant Staphylococcus aureus (MRSA) culture. Attainment of a calculated AUC/MIC ≥400 was compared between patients with troughs in the reference range of 15 to 20 mg/L and those with troughs in the following ranges: <10, 10 to 14...
June 2017: Journal of Pharmacy Practice
Adrian Wong, Aaron J Pickering, Brian A Potoski
BACKGROUND: Dosing of intravenous acyclovir for herpes encephalitis in obese patients is recommended to be based on ideal body weight. However, limited data support this recommendation, and recent data suggest this may lead to underdosing. OBJECTIVE: To determine national dosing practices of intravenous acyclovir across a range of patient weights. METHODS: A survey was distributed to members of the American College of Clinical Pharmacy Critical Care and Infectious Diseases Practice & Research Networks listservs...
June 2017: Journal of Pharmacy Practice
Jessica Gillon, Meng Xu, James Slaughter, M Cecilia Di Pentima
INTRODUCTION: The use of vancomycin is common among hospitalized children. We sought to evaluate the impact of prospective audit with real-time feedback on vancomycin use and pharmacy costs. METHODS: Vancomycin use was evaluated at Monroe Carell Jr Children's Hospital at Vanderbilt (MCJCHV) before and after the implementation of prospective audit with intervention and feedback to providers in 2012. Antibiotic use was compared to academic children's hospitals with established antimicrobial stewardship programs (ASPs)...
June 2017: Journal of Pharmacy Practice
Jacqueline M Theodorou, Yogini Patel, Patricia Ford
Pharmacologic agents for the treatment and prevention of venous thromboembolism in the cancer patient population are limited. Currently, low-molecular-weight heparin is recommended by national consensus guidelines for this indication. Rivaroxaban, an oral factor Xa inhibitor, is Food and Drug Administration (FDA) approved for the treatment and prevention of venous thromboembolism and offers the convenience of oral fixed-dose regimens, no routine laboratory monitoring, and has few drug and dietary interactions; however, its use in patients with cancer has not been largely studied...
June 2017: Journal of Pharmacy Practice
Carrie Koenigsfeld, Morgan Sayler, Hayden L Smith, Kristin Meyer, Nicholas Lehman, Craig Logemann, Michelle Bottenberg, Ginelle Bryant, Molly Obermark
PURPOSE: Study goal was to assess the impact of the 2013 American College of Cardiology and the American Heart Association (ACC/AHA) Cholesterol Guidelines on patients in the fourth statin benefit group which included patients aged 40 to 75 years, without diabetes or clinical atherosclerotic cardiovascular disease (ASCVD), and have an ASCVD score ≥7.5%. These patients could benefit from treatment interventions by a pharmacist. METHODS: Patients were identified from electronic health records...
June 2017: Journal of Pharmacy Practice
Emily Higdon, Jennifer D Twilla, Christopher Sands
Fluoroquinolones are extensively used to treat a variety of common bacterial infections. Due to their extensive use in clinical practice, increases in neuropsychiatric events have been reported. We discuss the case of a young female who developed visual hallucinations after 2 doses of moxifloxacin. After discontinuation of the moxifloxacin, the patient's symptoms completely resolved. While one other case report exists with moxifloxacin, this case is unique in comparison. Our patient was a young female with no kidney dysfunction, no drug abuse history, absence of polypharmacy, and no previous psychological history that would have put her at an increased risk of drug-induced psychosis...
June 2017: Journal of Pharmacy Practice
Michiaki Myotoku, Sachiko Omotani, Yasutoshi Hatsuda, Hiroki Konishi, Yoshihiko Hirotani
OBJECTIVE: A palliative care knowledge survey was conducted involving pharmacy students to examine their perceived usefulness and the educational effect of clinical training in hospitals. METHODS: A questionnaire sheet was distributed to fifth-year pharmacy students before and after clinical training. The questionnaire consisted of questions to clarify the details of palliative care-related training in hospitals and students' knowledge of such care. The respondents were divided into 2 groups: those who participated in palliative care team (PCT) rounds (group A: 57) and those who did not (group B: 57)...
June 2017: Journal of Pharmacy Practice
Mollie W Sheron, Shannon L Holt, Christopher W Ingram
Bacillus Calmette-Guérin (BCG) is a live, attenuated strain of Mycobacterium bovis that is used to treat superficial bladder cancer. Although its use is typically associated with only mild, localized side effects, rare systemic complications can occur. Disseminated mycobacterium infections after BCG therapy have been reported in over 30 cases; however, central nervous system (CNS) infections do not commonly occur. We report a 74-year-old male who developed a M. bovis cerebellar abscess after receiving intravesical BCG infusion for bladder cancer for less than 1 year...
June 2017: Journal of Pharmacy Practice
Anna Schreck Bird, Philip J Gregory, Mohamed A Jalloh, Zara Risoldi Cochrane, Darren J Hein
OBJECTIVE: To evaluate whether clinical data support the safety and efficacy of probiotics for the management of infantile colic. BACKGROUND: Probiotics have been suggested as a potential strategy for infantile colic, and the specific species that have been studied in healthy infants are considered to be safe. METHODOLOGY: A systematic review was conducted to identify randomized controlled trials (RCTs) evaluating the use of probiotic supplementation in infants with colic...
June 2017: Journal of Pharmacy Practice
Valentine Uche Odili, Anthonia Obumneke Obieche, Kingsley Chiedu Amibor
PURPOSE: The study investigated the level of adherence and factors affecting adherence to antiretroviral treatment (ART). METHODS: The study sample consisted of 300 HIV-infected patients who received ART in the Antiretroviral Clinic of Central Hospital, Agbor, Delta State, Nigeria. Self-reported adherence to ART in the previous 1 month prior to the study as well as determinants of adherence were assessed using a questionnaire. RESULTS: The most frequently used ART regimen was zidovudine + lamivudine + nevirapine...
June 2017: Journal of Pharmacy Practice
Maria A Sorbera, Michelle L Friedman, Rebecca Cope
Due to the intimate relationship between liver and kidney disease in hepatitis C virus (HCV) infection, treatment options for HCV-positive patients at any stage of chronic kidney disease (CKD) are essential. The availability of second-generation, direct-acting antiviral (DAA) combinations has allowed for the advent of interferon-sparing treatment regimens with shorter durations and minimal side effects. While many of the second-generation DAAs are principally metabolized by the hepatic system, dosing in severe renal impairment (creatinine clearance [CrCl] <30 mL/min) or dialysis has remained questionable due to limited experience...
June 2017: Journal of Pharmacy Practice
Courtney S Davis, Leigh Ann R Ross, Lauren S Bloodworth
OBJECTIVE: The national initiative, Project IMProving America's Communities Together (IMPACT): Diabetes, was intended to scale a proven American Pharmacists Association (APhA) Foundation process model, which integrates pharmacists on the collaborative health-care team, in communities greatly affected by diabetes to improve key indicators of diabetes. This article discusses the results from 1 community in Mississippi. METHODS: This national prospective study followed patients with a hemoglobin A1c (HbA1c) >7% from September 2011 to January 2013...
June 2017: Journal of Pharmacy Practice
Nicholas P Gazda, Lucas A Berenbrok, Stefanie P Ferreri
OBJECTIVE: To compare the return on investment (ROI) of an integrated practice model versus a "hub and spoke" practice model of pharmacist provided medication therapy management (MTM). METHODS: A cohort retrospective analysis of MTM claims billed in 76 pharmacies in North Carolina in the 2010 hub and spoke practice model and the 2012 "integrated" practice model were analyzed to calculate the ROI. RESULTS: In 2010, 4089 patients received an MTM resulting in 8757 claims in the hub and spoke model...
June 2017: Journal of Pharmacy Practice
Lauren M J Hutton, Andrew J Cave, Renée St-Jean, Hoan Linh Banh
PURPOSE: Summarize available information regarding clinical impact of citalopram on the QTc interval. METHODS: A literature search was conducted in Pubmed, EMBASE, and Cochrane databases using the MeSH term "long QT syndrome" and key word "citalopram" on July 11, 2014. RESULTS: Thirty-one studies were evaluated with 4 included in this review. Studies were excluded if they reported acute overdoses of citalopram or did not report on patient-specific risk factors for long QT syndrome (eg, hypokalemia, bradycardia, and increased age)...
June 2017: Journal of Pharmacy Practice
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No abstract text is available yet for this article.
April 2017: Journal of Pharmacy Practice
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No abstract text is available yet for this article.
April 2017: Journal of Pharmacy Practice
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