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Journal of Pharmacy Practice

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https://www.readbyqxmd.com/read/28343445/a-case-of-anagrelide-induced-nonischemic-cardiomyopathy-in-a-patient-with-essential-thrombocythemia
#1
Pritpal Singh
BACKGROUND: Anagrelide is an established treatment option for essential thrombocythemia (ET). Cardiovascular adverse events can occur with its use including heart failure and cardiomyopathy. CASE REPORT: A 52-year-old African American male with ET presented with chest pain, shortness of breath, and dyspnea on exertion. His ET was managed with hydroxyurea 1500 mg by mouth twice a day and anagrelide 1 mg by mouth 3 times a day. The patient was receiving anagrelide for approximately 2 years prior to presentation...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28343444/a-pilot-study-for-antimicrobial-stewardship-post-discharge
#2
Justin M Jones, Nathan D Leedahl, Ashley Losing, Paul J Carson, David D Leedahl
PURPOSE: Lack of patient follow-up is a major concern during care transitions, and the role of an antimicrobial stewardship program (ASP) in assessing antimicrobial regimens after hospital discharge is not well described. We implemented an expanded ASP to include patients recently discharged from the hospital and measured its impact on inappropriate antimicrobial therapy 72 hours after inpatient culture data were finalized. METHODS: A prospective cohort study was conducted at a 583-bed tertiary care center in the Upper Midwest of America...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28343443/lacosamide-induced-recurrent-ventricular-tachycardia-in-the-acute-care-setting
#3
Theodore J Berei, Matthew P Lillyblad, Adrian K Almquist
Lacosamide is a new-generation antiepileptic drug (AED) most commonly used adjunctively in the setting of partial-onset seizures refractory to traditional therapy. We describe the first case report, to our knowledge, of a patient who developed recurrent, sustained ventricular tachycardia with multiple administrations of lacosamide in an acute setting. A 70-year-old woman with a history significant for valvular heart disease was admitted to the inpatient cardiology service for worsening heart failure. On hospital day 7, she received a bioprosthetic aortic valve...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28205446/intramuscular-ziprasidone-dosing-for-acute-agitation-in-the-pediatric-emergency-department
#4
Tammy Nguyen, Jillian Stanton, Robin Foster
BACKGROUND: Intramuscular (IM) ziprasidone is often used to manage acute agitation. Limited data exist on the pediatric dosing of ziprasidone in the emergency department (ED). OBJECTIVE: To characterize the mg/kg dosing differences between pediatric ED patients who respond to an initial dose of ziprasidone versus patients who do not. METHODS: This was a retrospective, observational study of 5- to 18-year-old patients who were treated with IM ziprasidone in the pediatric ED from 2007 to 2015...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28205445/severe-hypertriglyceridemia-induced-by-sirolimus-treated-with-medical-management-without-plasmapheresis
#5
Kazuhiko Kido, Rickey A Evans, Anil Gopinath, Jeremy D Flynn
Hypertriglyceridemia and hyperlipidemia are the most remarkable metabolic complications seen with long-term sirolimus therapy. We report the case of a 36-year-old woman status post bilateral lung transplantation on a maintenance immunosuppression regimen of sirolimus, tacrolimus, and prednisone who presented with status migrainosus, chest pain, abdominal discomfort, and triglyceride levels greater than 4425 mg/dL. In previously reported cases of severe hypertriglyceridemia that developed on maintenance sirolimus therapy, plasmapheresis has been utilized as an early strategy to rapidly lower triglycerides in order to minimize the risk of acute complications such as pancreatitis, but our case was managed medically without plasmapheresis...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28125922/ace-inhibitor-induced-angioedema-of-the-small-bowel
#6
Kent L Wilin, Michael J Czupryn, Richard Mui, Anas Renno, Julie A Murphy
Angiotensin-converting enzyme (ACE) inhibitors are known to cause angioedema. Most ACE inhibitor-induced angioedema cases describe swelling in the periorbital region, tongue, and pharynx. We describe a case of a 62-year-old female with presumed angioedema of the small bowel after more than a 2-year history of lisinopril use (with no recent changes in her dose of 40 mg orally twice daily). The patient presented with nausea and intermittent left middle and upper quadrant abdominal pain and denied history of angioedema or swelling with any medications or any history of abdominal pain...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28110618/expanding-ambulatory-care-pharmacy-residency-education-through-a-multisite-university-affiliated-model
#7
Sarah K Schweiss, Sarah M Westberg, Jean Y Moon, Todd D Sorensen
INTRODUCTION: As the health-care system evolves and shifts to value-based payment systems, there is a recognized need to increase the number of ambulatory care trained pharmacists. OBJECTIVE: The objective of this article is to describe the administrative structure of the University of Minnesota Postgraduate Year 1 (PGY1) Pharmacy Residency program and to encourage adoption of similar models nationally in order to expand ambulatory care residency training opportunities and meet the demand for pharmacist practitioners...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28110617/characterization-of-drug-related-problems-occurring-in-patients-receiving-outpatient-antimicrobial-therapy
#8
Cory M Hale, Jeffrey M Steele, Robert W Seabury, Christopher D Miller
BACKGROUND: Despite the numerous benefits of outpatient parenteral antimicrobial therapy (OPAT), appreciable risks of drug-related problems (DRPs) exist. No studies to date comprehensively assess DRPs in this population. OBJECTIVES: Objectives of this study were to (1) characterize the frequency and types of DRPs experienced by patients discharged on OPAT and (2) determine the fraction of adverse drug reactions (ADRs) resulting in hospital readmission or emergency department (ED) presentation and changes in therapy...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28292233/members-in-the-news
#9
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28292232/members-in-the-news
#10
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26801656/assessment-of-postgraduate-year-2-pharmacy-residency-programs-within-the-veterans-affairs-healthcare-system
#11
Jennifer G Naples, Emily H Mantovani, Tracie Rothrock-Christian, Jamie N Brown
PURPOSE: Despite the increasing importance placed on advanced training for clinical pharmacists, literature describing postgraduate year 2 (PGY2) residency opportunities is limited. The objective of this study was to describe characteristics of PGY2 programs within the Veterans Affairs (VA) healthcare system. METHODS: An online survey addressing attributes of PGY2 residency programs was electronically distributed to VA residency program directors (RPDs). RESULTS: Responses from 27 (32...
April 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28093958/president-s-address
#12
Joseph Pinto
No abstract text is available yet for this article.
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28093957/new-faculty-members-at-touro-college-of-pharmacy-new-york
#13
(no author information available yet)
No abstract text is available yet for this article.
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28093956/praluent-alirocumab-induced-renal-injury
#14
Kenar D Jhaveri, Valerie S Barta, James Pullman
No abstract text is available yet for this article.
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26712651/impact-of-tranexamic-acid-in-total-knee-and-total-hip-replacement
#15
Jaclyn A Boyle, Mate M Soric
OBJECTIVE: To evaluate the net clinical benefit of tranexamic acid use in patients undergoing total knee or total hip replacement. METHODS: This is a retrospective study of patients undergoing total knee or total hip replacement. The primary outcome was the net clinical benefit of tranexamic acid use. Secondary outcomes included length of stay, incidence of venous thromboembolism, change in hemoglobin, and number of units of blood transfused. RESULTS: Four hundred and six patients were screened for inclusion and 327 patients met inclusion criteria; 174 patients received tranexamic acid versus 153 patients who received usual care...
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26702028/desirable-skills-in-new-pharmacists
#16
Catherine E O'Brien, Schwanda K Flowers, Cindy D Stowe
OBJECTIVE: To compare survey responses between licensed pharmacists who work with or employ new graduates and graduating senior pharmacy students at a college of pharmacy. DESIGN: This was a retrospective analysis of surveys given to 2 groups of pharmacists and students. Responses to items regarding importance of desirable qualities in new pharmacists and level of preparation of new graduates were analyzed. Qualities included drug information, pharmacology, therapeutics, communication with patients/customers or health care professionals, professionalism, ethics, management, and conflict resolution...
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26702027/evaluating-the-impact-of-medication-safety-alerts-on-prescribing-of-potentially-inappropriate-medications-for-older-veterans-in-an-ambulatory-care-setting
#17
Adam J Vanderman, Jason M Moss, William E Bryan, Richard Sloane, George L Jackson, S Nicole Hastings
Potentially inappropriate medications (PIMs) have been associated with poor outcomes in older adults. Electronic health record (EHR)-based interventions may be an effective way to reduce PIM prescribing. The main objective of this study was to evaluate changes in PIM prescribing to older adult veterans ≥65 years old in the ambulatory care setting preimplementation and postimplementation of medication alert messages at the point of computerized provider order entry (CPOE). Additional exploratory objectives included evaluating provider type and patient-provider relationship as a factor for change in PIM prescribing...
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26677861/development-and-implementation-of-clinical-pharmacist-services-within-an-integrated-medical-group
#18
Kerri T Musselman, Leticia R Moczygemba, Andrea L Pierce, Mary-Beth F Plum, Deborah K Brokaw, David L Kelly
BACKGROUND: In 2012, pharmacists were integrated into a medical group to provide direct patient care, drug information activities, and health care provider education. The medical group encompasses 40 primary care and 60 specialty offices in Virginia. OBJECTIVE: To describe the development and implementation of clinical pharmacist services integrated within a medical group. METHODS: Pharmacists' roles and responsibilities, type and number of patient encounters, and identification of strategies to facilitate implementation are described...
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26584848/statin-use-with-the-atp-iii-guidelines-compared-to-the-2013-acc-aha-guidelines-in-hiv-primary-care-patients
#19
Pansy Elsamadisi, Agnes Cha, Elise Kim, Safia Latif
BACKGROUND: The 2013 Cholesterol Guidelines include a new atherosclerotic cardiovascular disease (ASCVD) risk calculator that determines the 10-year risk of coronary heart disease and/or stroke. The applicability of this calculator and its predecessor, the Framingham risk score (FRS) in Adult Treatment Panel (ATP) III, has been limited in patients with HIV. The objective of this study was to compare the risk scores of ASCVD and FRS in the initiation of statin therapy in patients with HIV...
February 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26519253/perceived-benefit-of-teaching-patient-safety-to-pharmacy-students-by-integrating-classroom-teaching-with-introductory-ippe-visits
#20
Katy E Trinkley, Edward T Van Matre, Scott W Mueller, Robert L Page, Kavita Nair
INTRODUCTION: Ensuring a culture that prioritizes and implements patient safety requires educating all future health care professionals to prepare them for their active role in reducing medical errors. There is limited literature describing integration of patient safety education into the curriculum of health care professionals, including pharmacists. The purpose of this study was to evaluate the perceived benefit of integrating patient safety education into a pharmacy curriculum. METHODS: Second-year pharmacy students (P2s) completed a patient safety self-study, followed by in-class and experiential application of a root cause analysis (RCA)...
February 2017: Journal of Pharmacy Practice
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