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Journal of Human Hypertension

Caitlynd Myburgh, Hugo W Huisman, Catharina M C Mels
Oxidative stress has been implicated in the development of hypertension, arterial stiffness and atherosclerosis. Optimal functioning of the enzymatic antioxidant system is central to prevent increased oxidative stress and its consequences. We aimed to investigate the relationships of ambulatory blood pressure and carotid intima-media thickness with enzyme activities of the glutathione cycle in 396 young, black and white South Africans of the African-PREDICT study. Ambulatory blood pressure and carotid intima-media thickness were measured and glutathione peroxidase and glutathione reductase activities were analyzed...
March 12, 2018: Journal of Human Hypertension
Eugenia Gkaliagkousi, Panagiota Anyfanti, Sophia Chatzimichailidou, Areti Triantafyllou, Antonios Lazaridis, Spyros Aslanidis, Stella Douma
Predictors of adverse cardiovascular outcomes include elevated nighttime systolic blood pressure (SBP) and a non-dipping pattern. We investigated whether these factors correlate with systemic inflammation, cardiovascular risk, and markers of central and peripheral vascular damage in rheumatoid arthritis (RA), a disease characterized by excess cardiovascular risk. Twenty-four-hour ambulatory blood pressure monitoring was applied in patients and controls. Vascular assessments included measurement of arterial stiffness (pulse wave velocity) and carotid atherosclerosis (carotid intima-media thickness)...
March 9, 2018: Journal of Human Hypertension
Anna Vittoria Mattioli, Matteo Ballerini Puviani, Alberto Farinetti
No abstract text is available yet for this article.
March 7, 2018: Journal of Human Hypertension
Sunil K Nadar, Michael Stowasser
No abstract text is available yet for this article.
March 1, 2018: Journal of Human Hypertension
Jian-Liang Zhang, Hui Yu, Ying-Wei Hou, Ke Wang, Wen-Shan Bi, Liang Zhang, Qian Wang, Pan Li, Man-Li Yu, Xian-Xian Zhao
Treatment of hypertension with thiazide diuretics may trigger hypokalemia, hyperglycemia, and hyperuricemia. Some studies suggest simultaneous potassium supplementation in hypertensive patients using thiazide diuretics. However, few clinical studies have reported the impact of long-term potassium supplementation on thiazide diuretic-induced abnormalities in blood glucose and uric acid (UA) metabolisms. One hundred hypertensive patients meeting the inclusion criteria were equally randomized to two groups: IND group receiving indapamide (1...
March 1, 2018: Journal of Human Hypertension
Vivek Vashishtha, Kalpana Kumari Barhwal, Vineet Kumar Malhotra, Ashish Kumar, Sunil Kumar Hota, Tsering Norboo, Om Prakash Chaurasia
Hypoxic exposure at high-altitude (HA) modulates blood pressure (BP). High prevalence of hypertension among native highlanders (NH) has been reported. However, information on prevalence and determinants of hypertension in acclimatized young lowlanders (ALL) staying at HA for different durations is sparse. We aimed to determine the prevalence of hypertension in ALL staying at HA for different durations and its association with cardiovascular risk factors. Male volunteers were categorized on the basis of their duration of stay at HA; Lowlanders (LL) (0 months; n = 151), ALL (1-24 months; n = 519) and NH (n = 103)...
February 26, 2018: Journal of Human Hypertension
Jo S Stenehjem, Kirsti V Hjerkind, Tom I L Nilsen
Adiposity and inactivity have been associated with increased risk of hypertension. However, reports on the joint effect of these two risk factors in relation to hypertension are scarce and their interaction poorly understood. We prospectively examined both independent and joint effects of measured body mass index (BMI) and self-reported physical activity on the risk of hypertension. We conducted a longitudinal study of 11,238 men and 15,301 women who participated in the Nord-Trøndelag Health Study (HUNT) in Norway...
February 26, 2018: Journal of Human Hypertension
Shenghui Li, Jin Hua, Haifa Hong, Yanling Wang, Jun Zhang
Interpregnancy interval and maternal age are associated with birth outcomes. However, it is unknown regarding their long-term effects on child health. We aim to assess the associations between interpregnancy interval and offspring's body mass index (BMI) and blood pressure (BP) at age of 7 years and to examine the role of maternal age in the associations. A secondary analysis was performed among 2604 mother-infant pairs in the prospective National Collaborative Perinatal Project, in which the children were followed up until 7 yrs of age...
February 23, 2018: Journal of Human Hypertension
Félix Rinfret, Franck Ouattara, Lyne Cloutier, Pierre Larochelle, Monica Ilinca, Maxime Lamarre-Cliche
Hypertension is a major cardiovascular risk factor. To address the disease adequately, most clinicians rely on home blood pressure monitoring (HBPM). However, the impact of unrecorded BP values on the precision and diagnostic performance of BP schedules is unknown. We obtained 103 HBP patients schedules from a previous study. Then, readings were randomly removed from each schedule in order to create new incomplete schedules using a resampling technique. We obtained 10,000 new incomplete schedules. For each number of randomly removed readings, the percentages of incomplete schedules outside a systolic/diastolic blood pressure (SBP/DBP) range of 5/3 mmHg were calculated from the same complete patient's schedule...
February 21, 2018: Journal of Human Hypertension
Hongfan Li, Xikun Han, Zunsong Hu, Jianfeng Huang, Jing Chen, James E Hixson, Dabeeru C Rao, Jiang He, Dongfeng Gu, Shufeng Chen
Previous studies have indicated that reactive oxygen species produced by NADPH oxidase (Nox) are important risk factors of hypertension. The current study aims to examine the associations of Nox-related genes with longitudinal blood pressure (BP) changes and the risk of incident hypertension in the Genetic Epidemiology Network of Salt Sensitivity (GenSalt) follow-up study. A total of 1,768 participants from 633 families were included in our analysis. Nine BP measurements were obtained in the morning at baseline and during two follow-up visits...
February 20, 2018: Journal of Human Hypertension
Fernando Botto, Sebastian Obregon, Fernando Rubinstein, Angelo Scuteri, Peter M Nilsson, Carol Kotliar
The main objective was to estimate the frequency of early vascular aging (EVA) in a sample of subjects from Latin America, with emphasis in young adults. We included 1416 subjects from 12 countries in Latin America who provided information about lifestyle, cardiovascular risk factors (CVRF), and anthropometrics. We measured pulse wave velocity (PWV) as a marker of arterial stiffness, and blood pressure (BP) using an oscillometric device (Mobil-O-Graph). To determine the frequency of EVA, we used multiple linear regression to estimate each subject's PWV expected for his/her age and systolic BP, and compared with observed values to obtain standardized residuals (z-scores)...
February 20, 2018: Journal of Human Hypertension
Xiaotian Liu, Yuqian Li, Ying Guo, Linlin Li, Kaili Yang, Ruihua Liu, Zhenxing Mao, Ronghai Bie, Chongjian Wang
The aim of the present study was to examine the prevalence, awareness, treatment, control, and potentially influencing factors of high blood pressure (HBP) in Chinese rural adults based on a cross-sectional study. Using data from the Rural Diabetes, Obesity and Lifestyle (RuralDiab) study, a total of 30,834 participants aged 18-74 years were enrolled for the epidemiological study. The multivariate logistic regression model including all selected potentially influencing factors was carried out for the adjusted odds ratios (ORs) and 95% confidence intervals (CIs)...
February 13, 2018: Journal of Human Hypertension
Şükrü Ulusoy, Gülsüm Özkan, Beyhan Güvercin, Yeliz Sökmen, Yunus Erdem
To determine how and how often blood pressure (BP) measurement is performed in health institutions. The researchers observed whether or not 84 physicians performed BP measurement. Immediately after BP measurement by the physician, this was repeated by the researchers in a manner compatible with HT guidelines. The physicians' and researchers' BP measurement results were compared. Physicians measured BP in only 37% (427) of 1130 consecutive patient examinations. None of the physicians "BP measurements were fully compatible with the guidelines" BP measurement recommendations...
February 8, 2018: Journal of Human Hypertension
Xiaotong Wang, Yajun Li, Huihui Li, Yeqing Gu, Yanqi Song, Qing Zhang, Li Liu, Ge Meng, Zhanxin Yao, Hongmei Wu, Yang Xia, Xue Bao, Hongbin Shi, Qian Su, Liyun Fang, Huijun Yang, Fei Yu, Shaomei Sun, Xing Wang, Ming Zhou, Huanli Jiao, Qiyu Jia, Kun Song, Yuntang Wu, Hong Chang, Kaijun Niu
Evidence suggests long-term chronic inflammation, as the pathological basis of formation and development, plays an important part in atherosclerosis. Immunoglobulins (Igs) provided key information on the humoral immune status. However, few studies have evaluated the correlation between Igs and hypertension and blood pressure (BP) in a general population. We designed a cross-sectional study to evaluate whether serum Ig levels are related to BP and the prevalence of hypertension. About 12,373 participants in Tianjin, China were recruited for this study...
February 7, 2018: Journal of Human Hypertension
Xu Chen, Yu Liu, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Kunpeng Deng, Cheng Cheng, Leilei Liu, Xinping Luo, Ruiyuan Zhang, Feiyan Liu, Qionggui Zhou, Chongjian Wang, Linlin Li, Lu Zhang, Bingyuan Wang, Yang Zhao, Junmei Zhou, Chengyi Han, Hongyan Zhang, Xiangyu Yang, Chao Pang, Lei Yin, Tianping Feng, Jingzhi Zhao, Ming Zhang, Dongsheng Hu
This study compared the ability of body mass index (BMI), waist circumference (WC), conicity index, and waist-to-height ratio (WHtR) to predict incident hypertension and to identify the cutoffs of obesity indices for predicting hypertension in rural Chinese adults. This prospective cohort study recruited 9905 participants aged 18-70 years during a median follow-up of 6 years in rural China. Logistic regression and receiver operating characteristic (ROC) curve analyses were used to assess the association, predictive ability, and optimal cutoffs (in terms of hypertension risk factors) of the four obesity indices: BMI, WC, conicity index, and WHtR...
February 7, 2018: Journal of Human Hypertension
Tero J W Pääkkö, Juha S Perkiömäki, Y Antero Kesäniemi, Antti S Ylitalo, Jarmo A Lumme, Heikki V Huikuri, Olavi H Ukkola
Ambulatory blood pressure (ABP) has been shown to have an association with left ventricular hypertrophy (LVH). We evaluated the association between ABP characteristics and the development of LVH during long-term follow-up (20 years) in 420 middle-aged subjects from OPERA cohort. ABP measurements (ABPM) were recorded and echocardiographic examinations were performed at baseline and revisit. Anthropometrics were measured and laboratory analyses performed at visit. The questionnaire presented to all participants elicited detailed information about their habits...
February 7, 2018: Journal of Human Hypertension
George Moschonis, Kalliopi Karatzi, Odysseas Androutsos, Christos Lionis, George P Chrousos, Yannis Manios
Excess body weight and fat mass levels in children have previously been associated with childhood hypertension. The aim of the current study was to identify anthropometric and body composition indices most strongly associated with hypertension and to propose relevant cut-off values for these indices, above which the likelihood of hypertension in schoolchildren aged 9-13 years old is increased. A sample of 2,665 children participated in a cross-sectional epidemiological study, the Healthy Growth Study. The current study enrolled 1,315 children with full data on blood pressure, anthropometric, and body composition indices...
February 6, 2018: Journal of Human Hypertension
Zhenzhen Qin, Fei Xu, Qing Ye, Hairong Zhou, Chao Li, Jing He, Zhiyong Wang, Xin Hong, Xiangyu Hou
Literature showed that sugar-sweetened beverages (SSBs) could increase the risk of developing hypertension in school students, but there is no reported evidence from China yet, so this study aims to investigate the association of the SSBs consumption and school students' hypertension in urban areas of Nanjing, China. A cross-sectional survey was conducted among primary and junior high school students selected from 32 primary schools and 16 junior high schools using a multi-stage random sampling method, with a total number of 10,091 participants involved...
February 6, 2018: Journal of Human Hypertension
Sungha Park, Peera Buranakitjaroen, Chen-Huan Chen, Yook-Chin Chia, Romeo Divinagracia, Satoshi Hoshide, Jinho Shin, Saulat Siddique, Jorge Sison, Arieska Ann Soenarta, Guru Prasad Sogunuru, Jam Chin Tay, Yuda Turana, Ji-Guang Wang, Yuqing Zhang, Kazuomi Kario
Hypertension is the leading cause of mortality throughout Asia. Home blood pressure monitoring has the potential to improve hypertension control and is a useful adjunct to conventional office blood pressure measurements due to its diagnostic accuracy and prognostic value in predicting cardiovascular outcomes. At present, there are no region-specific guidelines addressing the use of home blood pressure monitoring in Asia. Therefore, an expert panel was convened to address the use of home blood pressure monitoring and develop key recommendations to help guide clinical practice throughout the Asia region...
January 31, 2018: Journal of Human Hypertension
Camillo L C Junqueira, Maria Eliane C Magalhães, Andréa Araújo Brandão, Esmeralci Ferreira, Adriana S M Junqueira, José Firmino N Neto, Maria das Graças C Souza, Daniel Alexandre Bottino, Eliete Bouskela
Hypertension is associated with microcirculatory impairment. Our objectives were to evaluate endothelial function and inflammatory biomarkers in patients with resistant (RH) and mild to moderate (MMH) arterial hypertension in comparison to normotensives (control group-CG). Three groups, 25 patients each, have been investigated, by anamnesis, venous occlusion plethysmography (VOP) and serum determination of adhesion molecules (VCAM, ICAM), adiponectin, endothelin and C-reactive protein (CRP). Patients not using statins and with or without blood pressure control were also analyzed...
January 15, 2018: Journal of Human Hypertension
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