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Journal of Human Hypertension

Camillo L C Junqueira, Maria Eliane C Magalhães, Andréa Araújo Brandão, Esmeralci Ferreira, Adriana S M Junqueira, José Firmino N Neto, Maria das Graças C Souza, Daniel Alexandre Bottino, Eliete Bouskela
Hypertension is associated with microcirculatory impairment. Our objectives were to evaluate endothelial function and inflammatory biomarkers in patients with resistant (RH) and mild to moderate (MMH) arterial hypertension in comparison to normotensives (control group-CG). Three groups, 25 patients each, have been investigated, by anamnesis, venous occlusion plethysmography (VOP) and serum determination of adhesion molecules (VCAM, ICAM), adiponectin, endothelin and C-reactive protein (CRP). Patients not using statins and with or without blood pressure control were also analyzed...
January 15, 2018: Journal of Human Hypertension
C Restrepo, S K Patel, V Rethnam, E Werden, J Ramchand, L Churilov, L M Burrell, A Brodtmann
Cognitive impairment is common in patients with hypertension. Left ventricular hypertrophy (LVH) is recognised as a marker of hypertension-related organ damage and is a strong predictor of coronary artery disease, heart failure and stroke. There is evidence that LVH is independently associated with cognitive impairment, even after adjustment for the presence of hypertension. We conducted a systematic review that examined cognitive impairment in adults with LVH. Independent searches were performed in Ovid MEDLINE, Ovid psycInfo and PubMed with the terms left ventricular hypertrophy and cognition...
January 12, 2018: Journal of Human Hypertension
Markus P Schlaich, Melinda Carrington
No abstract text is available yet for this article.
January 10, 2018: Journal of Human Hypertension
Zhongqiu Hong, Tao Wu, Shuxian Zhou, Boshui Huang, Jingfeng Wang, Dongmei Jin, Dengfeng Geng
Uncertainties still remain in terms of the efficacy of anti-hypertensive treatment on the risk of major cardiovascular (CV) events within prehypertensive levels. This review aims to assess the efficacy and safety of anti-hypertensives on the CV risks in populations within prehypertensive levels. Randomized controlled trials (RCTs) concerning active treatment vs placebo in populations within prehypertensive levels were identified through electronic database and manual search. Outcomes included the first co-primary outcomes, stroke, heart failure (HF), myocardial infarction (MI), all-cause mortality, and cardiovascular mortality...
January 9, 2018: Journal of Human Hypertension
Chen Xie, Lingling Cui, Jicun Zhu, Kehui Wang, Nan Sun, Changqing Sun
Some debates exist regarding the association of coffee consumption with hypertension risk. We performed a meta-analysis including dose-response analysis aimed to derive a more quantitatively precise estimation of this association. PubMed and Embase were searched for cohort studies published up to 18 July 2017. Fixed-effects generalized least-squares regression models were used to assess the quantitative association between coffee consumption and hypertension risk across studies. Restricted cubic spline was used to model the dose-response association...
January 4, 2018: Journal of Human Hypertension
Zhengce Wan, Liu Hu, Mei Hu, Xiaomei Lei, Yuancheng Huang, Yongman Lv
Epidemiological studies demonstrated that Helicobacter pylori (H. pylori) infection was associated with cardiovascular disease and its risk factors. However, the association between H. pylori infection and hypertension remained unclear. The aim of this study was to investigate the association between H. pylori infection and prevalence of hypertension among Chinese adults. We performed a cross-sectional study of 5246 adult participants who were recruited from a health manage center. All participants underwent a 13C-urea breath test and a routine health check-up...
December 30, 2017: Journal of Human Hypertension
Joseph Yeboah, Bob Byington, Alain Bertoni
No abstract text is available yet for this article.
December 30, 2017: Journal of Human Hypertension
Tanjaniina Laukkanen, Setor K Kunutsor, Francesco Zaccardi, Earric Lee, Peter Willeit, Hassan Khan, Jari A Laukkanen
Emerging evidence suggests beneficial effects of sauna bathing on the cardiovascular system. However, the effects of sauna bathing on parameters of cardiovascular function and blood-based biomarkers are uncertain. We aimed to investigate whether sauna bathing induces changes in arterial stiffness, blood pressure (BP), and several blood-based biomarkers. We conducted an experimental study including 102 participants (mean age (SD): 51.9 (9.2) years, 56% male) who had at least one cardiovascular risk factor. Participants were exposed to a single sauna session (duration: 30 min; temperature: 73 °C; humidity: 10-20%)...
December 21, 2017: Journal of Human Hypertension
Antoine Cremer, Chloé Tambosco, Jean-Benoît Corcuff, Romain Boulestreau, Prune Gaillard, Marion Lainé, Georgios Papaioannou, Philippe Gosse
The hypothesis that vitamin D (25(OH)D) insufficiency plays a role in occurring of various disease has led to a rise in requests of dosages and to an increase of health-care costs. 25(OH)D insufficiency is associated with increased risk of cardiovascular disease and hypertension in many studies. Animal studies demonstrated that 25(OH)D insufficiency activates renin angiotensin system but corresponding humans data are limited. The aim of the study was to document relationship between 25(OH)D, blood pressure, and renin angiotensin system in hypertensive subjects...
December 18, 2017: Journal of Human Hypertension
Laura Hinz, Daniele Pacaud, Gregory Kline
Congenital adrenal hyperplasia (CAH) is often considered a pediatric endocrinology condition, but we present two cases of young adults who presented with hypertension. An 18-year-old woman was found to have hypertension and hypokalemia when she presented for gonadectomy for 46, XY gonadal dysgenesis. She was subsequently found to have low cortisol, elevated progesterone, and elevated aldosterone. Genetic testing confirmed 17-alpha hydroxylase deficiency (17OHD). Her case was unique in that 17OHD usually presents with hypoaldosteronism...
December 18, 2017: Journal of Human Hypertension
Mujibur Rahman, M Mostafa Zaman, Jessica Yasmine Islam, Jalil Chowdhury, Ham Nazmul Ahsan, Ridwanur Rahman, Mahtabuddin Hassan, Zakir Hossain, Billal Alam, Rubina Yasmin
In Bangladesh, morbidity and mortality due to non-communicable diseases (NCDs) has increased over the last few decades. Hypertension is an important risk factor for NCDs, specifically cardiovascular disease. The objective of this study was to assess prevalence and risk factors for hypertension and pre-hypertension among adults in Bangladesh. Data for this analysis were collected during the national NCD Risk Factor Survey of Bangladesh conducted in 2010 from a representative sample of men and women, aged 25 years or above...
December 11, 2017: Journal of Human Hypertension
Paula Moreira da Costa, Arthur Fernandes Cortez, Fabio de Souza, Gabriel de Souza Mares, Bruno Dussoni Moreira Dos Santos, Elizabeth Silaid Muxfeldt
Moderately increased albuminuria, defined as urinary albumin excretion rate (UAER) between 30 and 300-mg/24-h is a well-known cardiovascular risk factor, especially in diabetic and hypertensive patients. This study aim to analyze the prognostic value of baseline UAER in a still understudied group, patients with resistant hypertension (RHT). This is a prospective observational study, which had enrolled 1048 outpatients with RHT, who were submitted to a clinical-laboratory assessment and ambulatory blood pressure monitoring (ABPM) during the follow-up...
December 11, 2017: Journal of Human Hypertension
Kalyani B Sonawane, Ashish A Deshmukh, Mark S Segal
No abstract text is available yet for this article.
December 11, 2017: Journal of Human Hypertension
Stacy W Baird, Zhezhen Jin, Kazue Okajima, Cesare Russo, Joseph E Schwartz, Mitchell S V Elkind, Tatjana Rundek, Shunichi Homma, Ralph L Sacco, Marco R Di Tullio
Epidemiologic studies assessing the relationship between blood pressure (BP), body mass, and cardiovascular events have primarily been based on office BP measurements, and few data are available in the elderly. The aim of the present study was to evaluate the relationship between body mass index (BMI) and BP values obtained by ambulatory blood pressure monitoring (ABPM) as compared to office BP measurements, and the effect of anti-hypertensive treatment on the relationship. The study population consisted of 813 subjects participating in the cardiovascular abnormalities and brain lesions (CABL) study who underwent 24-h ABPM...
December 4, 2017: Journal of Human Hypertension
Maria W Skrzypkowska, Monika E Ryba-Stanisławowska, Bartosz Słomiński, Piotr G Gutknecht, Janusz Siebert, Jolanta M Myśliwska
Populations of CD34- and VEGFR2-expressing cells are responsible for regeneration of damaged endothelium and vascular remodelling. As their quantity and activity changes during cardiovascular diseases, they are potentially useful markers of cardiovascular health. The aim of our study was to investigate changes of various CD34+ and CD34+ VEGFR2+ populations in subjects with newly recognised hypertension and to evaluate whether observed alterations are influenced by clinical parameters and angiotensin II. Circulating CD34+ and CD34+ VEGFR2+ cells were analysed in peripheral blood samples by flow cytometry...
November 30, 2017: Journal of Human Hypertension
Daniel A Duprez, Natalia Florea, Sue Duval, Catherine Koukol, Jay N Cohn
Pharmacotherapy to protect the arteries may be appropriate for individuals with high-normal blood pressure who are at risk for future cardiovascular disease (CVD). Nebivolol (NEB) in contrast to atenolol (ATE) may have a beneficial effect on endothelial function and may be more effective than ATE in preventing CVD. Sixty subjects with preHTN or borderline BP and abnormal small artery elasticity (SAE) underwent evaluation with 10 tests, including large and small artery elasticity, resting and treadmill exercise BP, carotid intimal-media thickness, retinal vascular photography, micro-albuminuria, electrocardiography, echocardiography, and plasma B-type natriuretic peptide level...
November 28, 2017: Journal of Human Hypertension
Fu-Liang Zhang, Zhen-Ni Guo, Ying-Qi Xing, Yan-Hua Wu, Hao-Yuan Liu, Yi Yang
Hypertension has been recognized as a major risk factor for cardiovascular disease. We aimed to analyze the current prevalence, awareness, treatment, and control of hypertension in northeast China. This cross-sectional survey adopted the multistage stratified random cluster sampling method to obtain a representative sample of adults aged 40 years or older in the general population of northeast China. Hypertension was defined as a systolic blood pressure (SBP) ≥ 140 mm Hg, or diastolic blood pressure (DBP) ≥ 90 mm Hg, or self-reported use of antihypertensive medications in the last 2 weeks irrespective of BP...
November 27, 2017: Journal of Human Hypertension
Mandeep Singh, Atul Kotwal, Chetan Mittal, S Ram Babu, Sahul Bharti, C Venkata S Ram
While elevated blood pressure is a recognized risk factor for cardiovascular disease, the prevalence of hypertension still remains unclear for most populations. A door-to-door survey was conducted using modified WHO STEPS questionnaire in a group of villages under the Thavanampalle Mandal of Chittoor District in the state of Andhra Pradesh of South India. Data were collated and analyzed for 16,636 individuals (62.3% females and 37.7% males) above 15 years of age. Overall, prevalence of hypertension (as per JNC-7 classification) was found to be 27...
November 27, 2017: Journal of Human Hypertension
Fabio Fantini, Srilakshmi M Adhyapak, Kiron Varghese, Mary Varghese, Tinku Thomas
No abstract text is available yet for this article.
November 27, 2017: Journal of Human Hypertension
Mariana Arruda, Emanuela Mello Ribeiro Cavalari, Marcela Pessoa de Paula, Felipe Fernandes Cordeiro de Morais, Guilherme Furtado Bilro, Maria Caroline Alves Coelho, Nathalie Anne de Oliveira E Silva de Morais, Diana Choeri, Aline Moraes, Leonardo Vieira Neto
There are limited data regarding the frequency of hypertension in nonfunctioning adrenal incidentaloma (NFAI). Our objectives were to investigate rates of hypertension and resistant hypertension in NFAI patients, and compare them to a control group without adrenal adenoma. We also aimed to evaluate the relationship between cortisol levels after 1 mg-dexamethasone suppression test (DST) and hypertension in NFAI patients. We selected 40 patients with NFAI and 40 control patients over the age of 18 without adrenal lesions on abdominal imaging...
November 24, 2017: Journal of Human Hypertension
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