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Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research

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https://www.readbyqxmd.com/read/30215538/comparative-outcomes-of-preoperative-chemoradiotherapy-and-selective-postoperative-chemoradiotherapy-in-clinical-stage-t3n0-low-and-mid-rectal-cancer
#1
Yu Lin, Huiming Lin, Zongbin Xu, Sunzhi Zhou, Pan Chi
Purpose/aim: Preoperative chemoradiotherapy (pre-CRT) and total mesorectal excision (TME) have become the standard of care for patients with locally advanced rectal cancer (LARC). Nevertheless, it is a controversial issue whether pre-CRT in cT3N0M0 patients would result in potential overtreatment. MATERIALS AND METHODS: In total, 183 clinical stage IIA rectal cancer patients treated with and without pre-CRT between 2011 and 2014 were retrospectively analyzed. Capecitabine/FOLFOX/CAPOX chemotherapy was co-administered with preoperative radiotherapy...
September 14, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30212251/perioperative-efficiency-vs-quality-of-care-do-we-always-have-to-choose
#2
Mikhail Chernov, Angela Vick, Sujatha Ramachandran, Shamantha Reddy, Galina Leyvi, Ellise Delphin
INTRODUCTION: ATTEMPTS to enforce optimization practices for operating room (OR) efficiency are often interpreted as a "pressure for production" which threatens patient safety. The aim of this study is to assess if and how improvements in OR efficiency affect patient safety and thus the quality of care. METHODS: In an attempt to optimize OR efficiency, a new OR management approach "Integrated Practice Improvement Solutions" (IPIS) was developed at the Weiler Division of Montefiore Medical Center in 2011...
September 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30212232/the-clearance-of-high-risk-human-papillomavirus-is-sooner-after-thin-loop-electrosurgical-excision-procedure-t-leep
#3
Wenying Zhang, Xiaodi Gong, Qiongwei Wu, Yu Liu, Guoying Lao, Jinyin Xiao, Longtao Yang, Ping Liu, Chengbin Ma
Purpose/aim of the study: To investigate high-risk human papillomavirus (HPV) infection clearance following thin loop electrosurgical excision procedure (t-LEEP) among patients with cervical benign lesion. MATERIALS AND METHODS: This retrospective study analyzed clinical data from patients with cervical benign lesion and HPV infection, who had undergone t-LEEP (T-Group), compared with patients with HPV infection undergone no treatment (NT-Group). Both groups attended regular follow-up between January 2008 and January 2012...
September 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30212230/anterior-iliac-spine-avulsion-fracture-treatment-options-in-young-athletes
#4
Iñigo Anduaga, Roberto Seijas, Albert Pérez-Bellmunt, Oriol Casasayas, Pedro Alvarez
PURPOSE: The aim of this research is to perform a literature review of the treatments available for the anterior iliac spines avulsion fracture on the young subjects. MATERIAL AND METHODS: We performed a systematic literature search for studies on spines avulsion fractures in young subjects from January 1, 2013, to February 2018; abstracts were screened by a single reviewer. For those studies meeting the eligibility criteria, full-text articles were obtained. RESULTS: From 112 studies found only six articles were included in this systematic review...
September 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30212225/black-race-and-body-mass-index-are-risk-factors-for-rhabdomyolysis-and-acute-kidney-injury-in-trauma
#5
Areg Grigorian, Viktor Gabriel, Ninh T Nguyen, Brian R Smith, Sebastian Schubl, Boris Borazjani, Victor Joe, Jeffry Nahmias
PURPOSE: Obesity has been shown in a single-center study to be a risk factor for rhabdomyolysis. More recently, sickle cell trait, known to be more prevalent in blacks, has been shown to be a risk factor for rhabdomyolysis. We hypothesized that in trauma patients, black race and a higher body mass index (BMI) are associated with risk for rhabdomyolysis and acute kidney injury (AKI). MATERIALS AND METHODS: The National Trauma Data Bank (NTDB) was queried (2013-2015) to identify patients age ≥18 years and grouped by BMI: normal (18...
September 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30204031/research-on-the-effects-of-levetiracetam-in-spinal-cord-injury-model-in-rats-an-experimental-study
#6
Egemen Nursoy, Mustafa Ogden, Bulent Bakar, Gungor Çagdaş Dincel, Uçler Kisa, Mehmet Faik Ozveren
PURPOSE: Despite advances in spinal biomechanic research, surgical techniques, and rehabilitation processes, no significant improvement has been identified in the treatment of spinal cord injury (SCI) and neurological recovery. AIM OF THE STUDY: This study was designed to investigate the potential therapeutic effects of methylprednisolone and levetiracetam on SCI. MATERIALS AND METHODS: In this study, 42 male Wistar Albino rats, each weighing 300-350 g, were separated into three main groups: control group, acute and subacute stage groups...
September 11, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30089423/-is-ct-scan-more-accurate-than-endoscopy-in-identifying-distance-from-the-anal-verge-for-left-sided-colon-cancer-a-comparative-cohort-analysis
#7
Renato Costi, Matteo Ricco', Giulio Negrini, Philippe Wind, Vincenzo Violi, Alban Zarzavadjian Le Bian
PURPOSES: Accurately localizing colorectal cancer during surgery may be challenging due to intraoperative limitations. In the present study, localization of left-sided colon cancer (LCC) by CT scan is compared to colonoscopy. MATERIAL AND METHODS: Consecutive patients with LCC located by colonoscopy and CT scan and undergoing left-hemicolectomy were included. Tumor distance from the anal verge (TDAV) was calculated by both CT-scan and colonoscopy, and then compared, using as reference TDAV measured intraoperatively...
August 8, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29144187/indispensable-points-for-research-on-antiadhesion-materials
#8
Katsunori Takagi
To prevent postoperative abdominal adhesions, many new antiadhesion materials have been developed all over the world. Few studies have analyzed the thickness of antiadhesive materials, but it is an important factor in maximizing adhesion prevention. The aspect of material thickness will needed for the future studies. However, few materials proceeded further than animal experimentation. Comparison tests between the newly developed antiadhesion materials and products already on the market will make it easier to conduct clinical trials...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28829651/experiences-with-osteoligamentoplasty-according-to-weiss-for-the-treatment-of-scapholunate-dissociation
#9
W Petersen, J Rothenberger, H E Schaller, A Rahmanian-Schwarz, M Held
BACKGROUND: In post-traumatic, dynamic, or static scapholunate (SL) instability, an SL ligament reconstruction is advisable to avoid long-term complications. However, a sufficient primary reconstruction is best achieved in acute injuries. For chronic SL dissociation, there is still no satisfying standard surgical technique. In this context, we evaluated the clinical outcome of Weiss's osteoligamentoplasty as a treatment option. METHODS: Over a three-year period, 16 patients with chronic and symptomatic SL dissociation Grade-II and III, without the signs of osteoarthrosis were, surgically treated using a bone-retinaculum-bone autograft from the distal radius...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28737441/irrigation-during-laparoscopic-appendectomy-for-complicated-appendicitis-time-to-review-current-guidelines
#10
Alessandro Pasculli, Valentina Ferraro, Angela Gurrado, Mario Testini
No abstract text is available yet for this article.
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28636498/a-novel-clinical-simulated-suture-education-for-basic-surgical-skill-suture-on-the-biological-tissue-fixed-on-standardized-patient-evaluated-with-objective-structured-assessment-of-technical-skill-osats-tools
#11
Zhanlong Shen, Fan Yang, Pengji Gao, Li Zeng, Guanchao Jiang, Shan Wang, Yingjiang Ye, Fengxue Zhu
BACKGROUND: Clinical-simulated training has shown benefit in the education of medical students. However, the role of clinical simulation for surgical basic skill training such as suturing techniques remains unclear. MATERIALS AND METHODS: Forty-two medical students were asked to perform specific suturing tasks at three stations with the different settings within four minutes (Station 1: Synthetic suture pad fixed on the bench, Station 2: Synthetic suture pad fixed on the standardized patient, Station 3: Pig skin fixed on the standardized patient); the OSATS (Objective Structured Assessment of Technical Skill) tool was used to evaluate the performance of students...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28598704/cancer-metastasis-to-the-peritoneum-bad-luck-or-dysregulated-biology
#12
Marc D Basson
No abstract text is available yet for this article.
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28557569/the-global-end-diastolic-volume-gedv-could-be-more-appropiate-to-fluid-management-than-central-venous-pressure-cvp-during-closed-hyperthermic-intrabdominal-chemotherapy-with-co-2-circulation
#13
Francisco Javier Redondo, David Padilla, Pedro Villarejo, Victor Baladron, Patricia Faba, Sergio Sánchez, José Ramón Muñoz-Rodríguez, Natalia Bejarano
BACKGROUND: Closed hyperthermic intraperitoneal chemotherapy (HIPEC) may increase abdominal pressure and effects of hemodynamic changes due to maintenance hyperthermia. Our aim was to analyze the safety and effectiveness of our closed technique with CO2 circulation in management fluid status and hemodynamic parameters by means of cardiac preload control measured by Global End Diastolic Values (GEDV) and a gas exchanger. MATERIAL AND METHODS: A Pilot Clinical Study that included 18 advanced ovarian cancer patients undergoing citoreductive surgery and HIPEC...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28541819/model-of-disc-degeneration-in-rat-tail-induced-through-a-vascular-isolation-of-vertebral-endplates
#14
Héctor Fernández-Susavila, Juan Pablo Pardo-Seco, Ramón Iglesias-Rey, Tomás Sobrino, Francisco Campos, Máximo Alberto Díez-Ulloa
Back pain is a major health problem. The degenerative cascade of the spine begins in the intervertebral disc, due to an impairment in the blood supply through the vertebral endplates. Our objective was to develop a novel disc degeneration model based on these premises, akin to the process in humans, in contrast to other proposed models (puncture, enzyme injection, aberrant loads,…) Material and methods: 37 Sprague-Dawley rats, 2 arms: (a) histological (n = 17, one died), en- bloc sections, Van Gieson staining, (Nisimura-Mochida criteria) and also collagen VI staining (tissue oxidative stress), four animals were euthanized every 2 weeks (2-8); and (b) imaging (n = 20, six wound sloughs), MRI 9...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28541751/a-novel-experimental-model-of-colorectal-endometriosis
#15
Anastasia Prodromidou, Vasilios Pergialiotis, Kitty Pavlakis, Laskarina Maria Korou, Maximos Frountzas, Dimitrios Dimitroulis, Georgios Vaos, Despina N Perrea
PURPOSE: Endometriosis is a disease that affects 6-10% of the female population, mainly women of reproductive age, and causes a variety of cyclic symptoms. Deep infiltrating endometriosis and in particular bowel involvement presents a challenge for modern surgery. To date, there are no experimental animal models in this field, demonstrating experimental induction of endometriosis directly attached to surface of the colon imitating human colorectal endometriosis; hence, the implementation of novel pharmaceutical and surgical strategies for the management of colorectal endometriosis is mainly limited to clinical studies...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28541718/colorectal-cancer-cells-adhere-to-traumatized-peritoneal-tissue-in-clusters-an-experimental-study
#16
Peter Falk, Andreas Jonsson, Torbjörn Swartling, Marie-Lois Ivarsson
Purpose/Aim: Colorectal malignity is one of the most common forms of cancer. The finding of free intraperitoneal colorectal cancer cells during surgery has been shown to be associated with poor outcome. The aim of this study was to develop an experimental model designed to investigate adhesion of colorectal cancer cells to the peritoneal surface. MATERIALS AND METHODS: Two human experimental models were developed, the first using cultured mesothelial cells and the second consisting of an ex vivo model of peritoneal tissue...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28525292/comparison-of-adjacent-segment-degeneration-after-nonrigid-fixation-system-and-posterior-lumbar-interbody-fusion-for-single-level-lumbar-disc-herniation-a-new-method-of-mri-analysis-of-lumbar-nucleus-pulposus-volume
#17
Shaofeng Yang, Yanan Liu, Zhaohua Bao, Jun Zou, Huilin Yang
PURPOSE: To evaluate the influence of a nonrigid fixation system and posterior lumbar interbody fusion on adjacent intervertebral disc degeneration by using MRI analysis of lumbar nucleus pulposus volume for single-level lumbar disc herniation. MATERIALS AND METHODS: We selected 112 patients who underwent nonrigid fixation (17 men and 44 women) or posterior lumbar interbody fusion (13 men and 38 women) for this retrospective study. Based on the T2-weighted magnetic resonance imaging (MRI) scans taken preoperatively, and 6, 12, and 24 months after surgery, the nucleus pulposus in the upper segments of the operated level was considered an ellipsoid, and their volumes were measured respectively and then compared between the two groups...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28525290/brief-commentary-on-the-article-a-novel-clinical-simulated-suture-education-for-basic-surgical-skill-suture-on-the-biological-tissue-fixed-on-standardized-patient-evaluated-with-objective-structured-assessment-of-technical-skill-osats-tools
#18
Meer M Chisthi
No abstract text is available yet for this article.
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28498785/laparoscopic-adrenalectomy-for-conn-s-syndrome-is-beneficial-to-patients-and-is-cost-effective-in-england
#19
Ioannis Christakis, John A Livesey, Gregory P Sadler, Radu Mihai
PURPOSE: Adrenalectomy has the potential to cure or improve the control of hypertension in patients with primary hyperaldosteronism due to unilateral adrenal adenoma (Conn's syndrome). This study assesses the patients' perception of, and costs associated with, laparoscopic adrenalectomy for Conn's syndrome. MATERIALS AND METHODS: Clinical, radiological, operative, and pathological data were collected on patients undergoing adrenalectomy for Conn's syndrome over 8-years period in a UK tertiary referral center...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28485994/copious-irrigation-versus-suction-alone-during-laparoscopic-appendectomy-for-complicated-appendicitis-in-adults
#20
Fengbo Sun, He Wang, Fengjuan Zhang, Xinming Zhang, Zhiyuan Xing, Shenglin Zhang, Haifeng Zhang, Ye Wang
OBJECTIVE: The objective of this study was to determine whether copious irrigation of peritoneal cavity during laparoscopic appendectomy for complicated appendicitis effectively reduces the incidence of postoperative complications and improves the postoperative recovery in adults compared with suction alone. METHODS: In this prospective randomized trial, adult patients with complicated appendicitis were randomized to "irrigation and suction"(IS) group or "suction only"(SO) group...
August 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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