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Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research

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https://www.readbyqxmd.com/read/30587050/percutaneous-endoscopic-necrosectomy-pen-combined-with-percutaneous-catheter-drainage-pcd-and-irrigation-for-the-treatment-of-clinically-relevant-pancreatic-fistula-after-pancreatoduodenectomy
#1
Jian Lin, Biqing Ni, Guozhong Liu
PURPOSE: This study aimed to evaluate the efficacy of percutaneous endoscopic necrosectomy (PEN) combined with percutaneous catheter drainage (PCD) and irrigation versus PCD for the treatment of clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreatoduodenectomy (PD). MATERIALS AND METHODS: A total of 34 consecutive patients who suffered from CR-POPF after PD were enrolled in this retrospective cohort study. 12 patients received PEN combined with PCD and irrigation, and 22 patients received PCD...
December 26, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30587049/application-of-pelnac%C3%A2-artificial-dermis-combined-with-vsd-in-the-repair-of-limb-wounds
#2
Zhengan Hao
No abstract text is available yet for this article.
December 26, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30574822/embryogenesis-of-ectopic-bronchogenic-cysts-keep-it-simple
#3
COMMENT
Petros Mirilas
No abstract text is available yet for this article.
December 21, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30574821/do-pelvic-organ-prolapse-quantification-examination-ba-and-d-guide-the-selection-of-operation-for-severe-pelvic-organ-prolapse
#4
Chunbo Li, Huimin Shu, Zhiyuan Dai
PURPOSE: To determine whether the preoperative Ba and D point could help to guide the choice of surgical procedure for POP. MATERIALS AND METHODS: This prospective cohort study included 250 subjects with anterior/apical defect from January 2012 to June 2015. All subjects underwent a complete preoperative evaluation and completed 12 months of follow-up. Based on the connection of preoperative Ba and D point of Pelvic Organ Prolapse Quantification (POP-Q), patients were assigned two groups: 137 patients who underwent anterior vaginal repair with mesh (AVM) and 113 patients who underwent AVM combined with sacrospinous ligament fixation (SSLF)...
December 21, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30574819/cd24-as-a-novel-predictive-biomarker-in-patients-with-hepatocellular-carcinoma-friend-or-foe
#5
COMMENT
Nikolaos Machairas, Diamantis I Tsilimigras, Demetrios Moris
No abstract text is available yet for this article.
December 21, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30543135/clinicopathological-and-prognostic-value-of-plasma-cd24-level-in-hepatocellular-carcinoma
#6
Abuduaiheti Maimaitiming, Xing Zhou, Xianxiong Ma, Yongming Huang, Qingbo Wang, Rui Deng, Yahui Ren, Xinqun Chai, Pei Zhang
PURPOSE: CD24 is overexpressed in hepatocellular carcinoma (HCC) tumor tissues and in the highly metastatic HCC cell lines. However, plasma CD24 level in HCC patients and the correlation of plasma CD24 level with clinicopathological factors and prognosis of HCC patients still remain unclear. MATERIALS AND METHODS: Enzyme-linked immunosorbent assay was used to detect plasma CD24 level in 86 HCC patients, 35 healthy subjects, 26 patients with liver cirrhosis and 23 patients with chronic hepatitis...
December 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30543132/perihilar-hepatectomy-for-hepatolithiasis-with-compressed-hilar-bile-duct-induced-by-perihilar-hyperplasia-of-liver
#7
Guangyu Chen, Feng Tian, Xin Zhao, Yan Chen, Tao Peng, Jingchi Cui, Dajiang Li, Yu He, Shuguang Wang
BACKGROUND: Stone recurrence is a major problem limiting the effects of surgical treatment for hepatolithiasis. It was showed that hyperplasia of perihilar liver may compress the hepatic portal and cause deficient bile flow because of compressed hilar bile duct, thereby leading to the formation of bile stasis and precipitating stone recurrence. This retrospective study aimed to evaluate the efficiency of perihilar hepatectomy for hepatolithiasis with compressed hilar bile duct induced by perihilar hyperplasia of liver...
December 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30543131/long-term-management-of-vascular-access-ports-in-nonhuman-primates-used-in-preclinical-efficacy-and-tolerability-studies
#8
Lucas A Mutch, Samuel T Klinker, Jody J Janecek, Melanie N Niewinski, Rachael M Z Lee, Melanie L Graham
Vascular access ports (VAPs) are an essential tool for long-term vascular access in preclinical studies and disease modeling in non-human primates (NHPs). We retrospectively reviewed central (inferior vena cava, IVC) and portal VAP implantation with the maintenance at our center from 15 January 2010 to 31 January 2018. In total, 209 VAPs were implanted for long-term drug administration and sampling. Patency was >95% at 6 months and >80% at 1 year for IVC VAPs and >90% at 6 months and >85% at 1 year for portal VAPs...
December 13, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30516078/comparative-analysis-for-five-fixations-of-pauwels-i-by-the-biomechanical-finite-element-method
#9
Matthew Jian-Qiao Peng, Hai-Yan Chen, XiangYang Ju, Yong Hu, Ashraf Ayoub, Balvinder Khambay, ZiQing Liu, Bo Bai
BACKGROUND: Little is known about how biomechanics govern the five fixtures such as DHS, MLS, DHS + LS, LP, and HA are accepted as common therapeutic techniques. AIMS AND OBJECTIVES: A series of numerical models for a femoral neck fracture of Pauwels-I will be constructed by innovative approach of finite element in order to determine the most optimized option in comparison with biomechanical performance. METHOD: Twenty sets of computer tomography scanned femora were imported onto Mimics to extract 3 D models; these specimens were transferred to Geomagic-Studio for a simulative osteotomy and kyrtograph; then, they underwent UG to fit simulative solid models; 5 sorts of fixture were then expressed by Pro-Engineer virtually...
December 5, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30499737/beneficial-effect-of-u-74389-g-and-sildenafil-in-an-experimental-model-of-flap-ischemia-reperfusion-injury-in-swine-histological-and-biochemical-evaluation-of-the-model
#10
Stavros-Loukas Karamatsoukis, Eleni-Andriana Trigka, Marianna Stasinopoulou, Antigoni Stavridou, Argyro Zacharioudaki, Kalliopi Tsarea, Maria Karamperi, Theodoros Pittaras, Othon Papadopoulos, Efstratios Patsouris, Nikolaos Nikiteas, Georgios C Zografos, Apostolos E Papalois
PURPOSE OF THE STUDY: Tissue reconstruction after burns, tumor excisions, infections or injuries is a frequent surgical challenge to avoid Ischemia-reperfusion injury. Lazaroids and sildenafil, through their mechanisms of action, have been studied for their protective effects on various organs subjected to IRI. In this study, we aimed to evaluate the therapeutic potential of U-74389G and sildenafil in a swine model of ischemia and reperfusion injury of latissimus dorsi flap. MATERIALS AND METHODS: Forty-two Landrace male pigs, weighing 28-35 kg, were equally (n = 6) randomized into the following groups: (a) Group I: control, (b) Group II: administration of U-74389G after ischemia, (c) Group III: administration of sildenafil after ischemia, (d) Group IV: administration of U-74389G and sildenafil after ischemia, (e) Group V: administration of U-74389G prior to ischemia, (f) Group VI: administration of sildenafil prior to ischemia, and (g) Group VII: administration of U-74389G and sildenafil prior to ischemia...
November 30, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30461324/intraoperative-vaginal-perforation-during-various-mid-urethral-sling-procedures-treating-female-stress-urinary-incontinence
#11
Peng-Hu Lian, Zhi-Gang Ji, Han-Zhong Li, He Xiao, Wei-Gang Yan, Zhong-Ming Huang
BACKGROUND: Incidence of intraoperative vaginal perforation is generally considered to be low but varies among different procedures. Vaginal perforation could not only prolong the surgeries and aggravate surgical trauma but also result in postoperative discomfort or even a second surgery. METHOD: Vaginal perforation, vaginal epithelial perforation, vaginal wall perforation, vaginal penetration, urinary incontinence were searched in PubMed, Cochrane, Embase database to identify the qualified clinical trial and relevant literature sources were also searched...
November 21, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30457408/current-status-of-liver-transplantation-using-marginal-grafts
#12
Amr Badawy, Toshimi Kaido, Shinji Uemoto
The use of marginal liver grafts has become an inevitable option because of the continuous increase in the number of patients awaiting liver transplantation and the severe shortage of suitable donors. Recently, several approaches have been adapted to expand the donor pool and improve the outcome of marginal grafts in both deceased and living donor liver transplantation. Accordingly, this review discusses the various types of marginal grafts in both deceased and living donor liver transplantation, their outcome and the up-to-date innovations or strategies to extend the donor pool and improve the patient and graft survival post-transplant...
November 20, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30457404/sirolimus-in-liver-transplant-recipients-with-hepatocellular-carcinoma
#13
Sam Grigg, Paul Gow, Neville Yeomans
No abstract text is available yet for this article.
November 20, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430890/association-of-frailty-with-delayed-recovery-of-gastrointestinal-function-after-elective-colorectal-cancer-resections
#14
Wenbin Gong, Xing Qi
Frailty is characterized by a state of vulnerability to poor resolution of homoeostasis after a stressor event and is a consequence of age-related decline in many physiological systems during a lifetime. To access the association between frailty and delayed recovery of gastrointestinal function in patients undergoing elective colorectal cancer resections, 241 patients who had undergone elective colorectal cancer resections from July 2015 to August 2017 were investigated. The association of frailty with delayed recovery of gastrointestinal function, length of stay (LOS), and whether or not to transfer into intensive care unit (ICU) were analyzed...
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430888/effects-of-isolated-impaired-fasting-glucose-on-brain-injury-during-cardiac-surgery-under-cardiopulmonary-bypass
#15
Tao Zhou, Suining Li, Daokang Xiang, Lufang Gao
OBJECTIVE: To evaluate the effects of isolated impaired fasting glucose (IIFG) on brain injury in patients undergoing cardiopulmonary bypass (CPB) surgery. METHODS: Patients with rheumatic heart valve disease who underwent elective mitral valve replacement were included and divided into control and IIFG groups. Pre-, intra-, and postoperative blood glucose levels, serum insulin levels, insulin resistance index (HOMA-IR), lactic acid levels, and neuron-specific enolase (NSE) and S100B levels were measured...
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430887/a-novel-method-of-damage-control-for-multiple-discontinuous-intestinal-injuries-with-hemorrhagic-shock-a-controlled-experiment
#16
Weihang Wu, Zhicong Cai, Nan Lin, Weijin Yang, Jie Hong, Li Lin, Zhixiong Lin, Junchuan Song, Yongchao Fang, Chen Lin, Hongwen Zhang, Dongsheng Chen, Yu Wang
AIM: In this study, we examined the effects of branched silicon tube (BST) and temporary closed circle (TCC) in a Beagle dog model of multiple transection of small intestine and discontinuities suspected intestinal necrosis with hemorrhagic shock. MATERIALS AND METHODS: Ten male Beagle dogs were randomly divided into two groups. Hemorrhagic shock was induced by bleeding. Intestine was severed. Suspected intestinal necrotic model by ligating the mesenteric vessels was established, with a small tertiary mesenteric vessel reserved...
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430886/pediatric-bronchogenic-cysts-a-case-series-of-six-patients-highlighting-diagnosis-and-management
#17
Jason E Cohn, Kimberly Rethy, Rajeev Prasad, Judy Mae Pascasio, Katie Annunzio, Seth Zwillenberg
PURPOSE: To present six cases of bronchogenic cysts while highlighting the diagnosis and management of this anomaly. MATERIALS AND METHODS: A retrospective chart review was conducted using our institution's Pathology database. The database was queried for "bronchogenic cyst." From 2006 through 2017, six unusual cases were identified. RESULTS: The six cases of bronchogenic cysts were located in the neck (two cases), chest wall, mediastinum (two cases), and thyroid...
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430880/response-to-letter-to-editor-re-comparison-of-the-2-tight-rope-technique-and-clavicular-hook-plate-for-the-treatment-of-rockwood-3-type-iii-acromioclavicular-joint-dislocation
#18
Hua Chen
No abstract text is available yet for this article.
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430878/the-efficacy-of-recombinant-platelet-derived-growth-factor-on-beta-tricalcium-phosphate-to-regenerate-femoral-critical-sized-segmental-defects-longitudinal-in-vivo-micro-ct-study-in-a-rat-model
#19
Mohammed Badwelan, Mohammed Alkindi, Sundar Ramalingam, Nasser Nooh, Khalid Al Hezaimi
BACKGROUND AND OBJECTIVES: Beta-tricalcium phosphate (beta-TCP) has been used for bone regeneration. The objective of this study was to assess longitudinally, the regeneration of critical sized segmental defects (CSSD) in rat femur using beta-TCP with or without recombinant platelet-derived growth factor (PDGF) through in vivo micro-computed tomography (micro-CT). MATERIALS AND METHODS: Following ethical approval unilateral femoral CSSD measuring 5 mm was surgically created, under general anesthesia, in 30 male Wistar-Albino rats (aged 12-18 months; weighing 450-500 g)...
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/30430869/research-on-the-effects-of-levetirasetam-in-spinal-cord-injury-model
#20
Panagiotis G Korovessis
No abstract text is available yet for this article.
November 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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