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Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research

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https://www.readbyqxmd.com/read/29469636/total-colpectomy-increases-the-risk-of-postoperative-hydronephrosis-in-vaginal-cancer-patients
#1
Octavian Constantin Neagoe, Mihaela Ionica, Dorin Nicolae Agapie
PURPOSE: Due to the rarity of vaginal cancer, surgical treatment results, and postoperative complications have been poorly described in the literature. The aim of this study was to improve current knowledge about the incidence of hydronephrosis following the surgical treatment of vaginal cancer. MATERIALS AND METHODS: 32 patients with vaginal cancer of the middle and upper third were matched with 32 cervical cancer patients (stages I and II) for comparison of long-term urological postoperative complications...
February 22, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29469635/in-the-experimental-model-of-acute-mesenteric-ischemia-the-correlation-of-blood-diagnostic-parameters-with-the-duration-of-ischemia-and-their-effects-on-choice-of-treatment
#2
Mikail Cakir, Dogan Yildirim, Fatma Sarac, Turgut Donmez, Semih Mirapoglu, Adnan Hut, Fazilet Erozgen, Omer Faruk Ozer, Melih Ozgun Gecer, Leyla Zeynep Tigrel, Oguzhan Tas
Purpose/Aim: Acute mesenteric ischemia is a syndrome characterized by sudden onset abdominal pain followed by intestinal necrosis. Morbidity and mortality increase with delayed diagnosis. Even with the latest radiological diagnostic methods, early diagnosis and initiation of treatment can be delayed. Using an experimental model, here we aim to determine the relationship between the laboratory parameters used to detect acute mesenteric ischemia and the duration of irreversible ischemia. MATERIALS AND METHODS: A total of 30 male Wistar albino rats were divided into five groups, all of which underwent general anesthesia: (i) Superior mesenteric artery (SMA) dissection with laparotomy was performed, and blood samples and intestinal segment samples were taken after 2 hr (Sham group); (ii) volvulus of one-third of the small intestines was performed manually by laparotomy, and blood samples and intestinal segment samples were taken after 2 hr (Volvulus group); (iii) SMA was ligated with laparotomy, and blood samples and intestinal segment samples were taken after 2 hr (SMA+ligated 2-hr group); (iv) SMA was ligated with laparotomy, and blood samples and intestinal segment samples were taken after 4 hr (SMA+ligated 4-hr group); and (v) SMA was ligated with laparotomy, and blood samples and intestinal segment samples were taken after 6 hr (SMA+ligated 6-hr group)...
February 22, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29469632/hybrid-reconstruction-of-the-aortic-arch-using-a-double-branched-stent-graft-in-a-canine-model
#3
Fan Qiao, Cunhua Su, Qingqi Han, Mengwei Tan, Jun Wang, Yang Liu, Fanglin Lu, Lin Han, Zhiyun Xu
PURPOSE: To report the results of a hybrid approach to aortic arch repair using an innovative unibody double-branched stent graft in a canine model. MATERIALS AND METHODS: The stent-graft system consists of two parts: the main body and two branches for reconstruction of the supra-arch branches. There is a 2-cm-long suturing portion at the proximal end of the main body. Twenty adult German sheep dogs underwent a hybrid surgical treatment to place the stent-grafts into the proximal descending aorta and the supra-arch branches...
February 22, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29469618/elastic-tpu-mesh-as-abdominal-wall-inlay-significantly-reduces-defect-size-in-a-minipig-model
#4
D Heise, R Eickhoff, A Kroh, M Binnebösel, U Klinge, C D Klink, U P Neumann, A Lambertz
BACKGROUND: The open abdomen with mesh implantation, followed by early reoperation with fascial closure, is a modern surgical approach in difficult clinical situations such as severe abdominal sepsis. As early fascial closure is not possible in many cases, mesh-mediated fascial traction is helpful for conditioning of a minimized ventral hernia after open abdomen. The aim of this study was to evaluate the clinical utilization of an innovative elastic thermoplastic polyurethane mesh (TPU) as an abdominal wall inlay in a minipig model...
February 22, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29442525/comparative-analysis-of-mesenchymal-stem-cells-from-bone-marrow-adipose-tissue-and-dental-pulp-as-sources-of-cell-therapy-for-zone-of-stasis-burns
#5
Ozan Luay Abbas, Orhan Özatik, Zeynep Burçin Gönen, Serdal Öğüt, Fikriye Yasemin Özatik, Hasan Salkın, Ahmet Musmul
INTRODUCTION: The implantation of mesenchymal stem cells (MSCs) has been shown to exert benefits for the survival of the zone-of-stasis. However, the clinical experience indicates the importance of selecting the right source and type of stem cells. Therefore, we planned the current study to perform a quantitative comparison of MSCs isolated from three different sources to provide information useful in selection of the optimal source and to see whether critical mechanisms are conserved between different populations...
February 14, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29431531/effect-of-human-placental-extract-treatment-on-random-pattern-skin-flap-survival-in-rats
#6
Jung Woo Kwon, Seung Eun Hong, So Ra Kang, Bo Young Park
BACKGROUND: Human placental extract (HPE), prepared from the placentas of healthy, postpartum females, displays various physiological activities, including antioxidative properties. In this study, a dorsal skin flap model was used to investigate the effect of HPE on flap viability in rats. MATERIALS AND METHODS: Forty male Sprague-Dawley rats underwent random-pattern skin flap surgeries. The animals were randomly divided among a control group and three treatment groups (localized injection (LI), 10 mg/kg/d localized HPE injections; low-dose treatment (LT), 10 mg/kg/d systemic HPE injections; high-dose treatment (HT), 40 mg/kg/d systemic HPE injections)...
February 12, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29420097/hemostatic-comparison-of-a-polysaccharide-powder-and-a-gelatin-powder
#7
Rahul K Singh, Bernhard Baumgartner, Jason R Mantei, Rhea N Parreno, Paul J Sanders, Kevin M Lewis, John J Barry
Purpose/Aim: Powdered hemostats have been widely adopted for their ease-of-use; however, their efficacy has been limited resulting in applications restricted to low-level bleeds. This study investigates the use of bovine-derived gelatin particles (BGP) as a standalone hemostatic powder and compare BGP to commercially available microporous polysaccharide hemospheres (MPH). MATERIALS AND METHODS: The powders were investigated for their hemostatic efficacy in a heparinized pre-clinical bleeding model limited to grade 1 and 2 bleeds on a validated intraoperative bleeding scale, which represents the accepted, clinical use of hemostatic powders...
February 8, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29420085/reactive-oxygen-species-play-a-biphasic-role-in-brain-ischemia
#8
Jiping Yang, Jinchong Qi, Baoxin Xiu, Bei Yang, Caihong Niu, Hua Yang
OBJECTIVE: Reactive oxygen species (ROS) are the essential mechanism involving in the ischemic process. Due to their complex characteristics, the precise effects of ROS on post-ischemic neurons remain uncertain. This study aimed to investigate the potential role of ROS in brain ischemia. METHODS: Dynamic ROS levels in the perifocal cortex were evaluated after right middle cerebral artery occlusion (MCAO) of SD rats. Furthermore the role of ROS was assessed following delayed treatment with the ROS scavenger dimethylthiourea (DMTU) after brain ischemia...
February 8, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29420082/invited-brief-commentary-sentinel-lymph-node-status-is-a-main-prognostic-parameter-needful-for-the-correct-staging-of-patients-with-melanoma-thicker-than-4-mm-single-institutional-experience-and-literature-meta-analysis
#9
John T Vetto
No abstract text is available yet for this article.
February 8, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29400574/comparison-of-posterolateral-fusion-and-posterior-lumbar-interbody-fusion-in-the-treatment-of-lumbar-spondylolithesis-a-meta-analysis
#10
Ying-Chun Chen, Lin Zhang, Er-Nan Li, Li-Xiang Ding, Gen-Ai Zhang, Yu Hou, Wei Yuan
AIM: Both posterior lumbar interbody fusion (PLIF) and posterolateral fusion (PLF) are the frequently-used techniques to treat lumbar spondylolithesis. The aim of this meta-analysis is to compare the safety and effectiveness between these two methods. MATERIALS AND METHODS: The multiple databases were used to search for the relevant studies, and full-text articles involved in the comparison between PLIF and PLF were reviewed. Review Manager 5.0 was adopted to estimate the effects of the results among selected articles...
February 5, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29393725/effects-of-laparascopic-hernia-repair-by-pirs-percutan-internal-ring-suturing-technique-on-testicular-artery-blood-supply
#11
Akgun Oral, Leyla Karaca, Ali Ahiskalioglu, Abdullah Yildiz, Murat Yigiter, Mehmet Emin Celikkaya, Temirlan Chyndolotov, Ahmet Bedii Salman
PURPOSE: Percutaneous internal ring suturing technique (PIRS) is a minimally invasive technique in pediatric inguinal hernia repair. In the present study, a negative effect on testicular blood flow using PIRS technique has been investigated. METHODS: Forty male patients were included in the study prospectively. Two groups were formed as conventional open surgery (Group I) and PIRS technique (Group II). The resistive index (RI) value of the testicular artery was measured prospectively by using SMI (superb micro-vascular imaging) software with the color doppler ultrasound technique preoperatively and postoperatively at the first month...
February 2, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29393721/rockwood-type-iii-acromioclavicular-joint-dislocation-are-we-still-fighting
#12
Roberto Seijas, Andrea Sallent, Oscar Ares
No abstract text is available yet for this article.
February 2, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29388858/a-purification-technique-for-adipose-derived-stromal-cell-cultures-leads-to-a-more-regenerative-cell-population
#13
Renee F Conway, Kevin M Okarski, John A Szivek
It has been demonstrated that adipose-derived stromal cells (ASCs) are a regenerative cell population with potential uses for bone and cartilage regeneration. However, the biomarker expression and heterogeneity of the population has not been thoroughly characterized. By analyzing biomarker expression, we aimed to understand the composition of ASC populations extracted using a common extraction technique in comparison to ASC populations given an additional purification step. Human adipose tissue samples were collected, and ASCs were extracted from these samples using a common, published extraction technique (primary extraction)...
February 1, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29388856/comparison-of-lidocaine-and-atropine-on-fentanyl-induced-cough-a-randomized-controlled-study
#14
Muhammet Emin Naldan, Zakir Arslan, Ayşenur Ay, Ahmet Murat Yayık
OBJECTIVE OF THE STUDY: Fentanyl and atropine are drugs used for analgesia during induction and for premedication, respectively. The aim of this study was to observe the effect of atropine used for premedication on cough developing in association with fentanyl use during anesthesia induction. METHODS: This was a single-blind, prospective, multi-arm, parallel, randomized clinical trial involving 120 patients between ages 3 and 15 years undergoing general anesthesia...
February 1, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29381439/efficacy-of-corticosteroid-injection-for-treatment-of-trigger-finger-a-meta-analysis-of-randomized-controlled-trials
#15
Shiwei Ma, Chunbo Wang, Jiang Li, Zhiyu Zhang, Yao Yu, Feng Lv
PURPOSE: To determine the efficacy and safety of corticosteroid injection for trigger finger by performing a meta-analysis of all relevant studies. METHODS: PubMed, EMBASE, and Cochrane Library databases were searched for randomized controlled trials (RCTs) comparing corticosteroid injection with other treatments for trigger finger. Pooled summary estimates for outcomes, including success rate, relapse rate, visual analogue score (VAS) and complications, were calculated as standardized mean difference (SMD) or relative risk (RR) either on a fixed- or random-effect model via Stata 12...
January 30, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29381437/diagnosis-and-treatment-of-75-patients-with-idiopathic-lobular-granulomatous-mastitis
#16
Jieqing Li
Idiopathic granulomatous lobular matitis (IGLM) is a rare non-specific inflammatory disease of the breast. Although IGLM is completely benign, it is easily confused with cancer due to progressive breast lump with firmly unilateral and discrete mass, nipple retraction and sinus formation. Patients with IGLM are usually associated with inflammation of the overlying skin. This study aimed to investigate the clinical characteristics of IGLM, treatment options and prognosis. From January 2010 to February 2015, 75 IGLM patients in our hospital were included, with an average age of 35...
January 30, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29381413/effectivity-of-biophysical-barriers-in-peridural-fibrosis-commentary-on-the-published-paper-by%C3%A2-%C3%A2-in-the-journal-of-investigative-surgery
#17
Panagiotis Korovessis
No abstract text is available yet for this article.
January 30, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29370551/tumor-biological-aspects-of-a-large-scale-retrospective-study-the-role-of-tumor-cell-heterogeneity-inflammation-and-aging-in-survival
#18
Ferenc Sipos, Györgyi Műzes
No abstract text is available yet for this article.
January 25, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29370544/evaluation-criteria-and-surgical-technique-for-transoral-access-to-the-thyroid-gland-experimental-study
#19
Alexander M Shulutko, Vasiliy I Semikov, Elkhan G Osmanov, Sergey E Gryaznov, Anna V Gorbacheva, Alla R Patalova, Gaukhar T Mansurova, Airazat M Kazaryan
BACKGROUND: The development of endoscopic techniques motivated surgeons to search for alternative and more cosmetic approaches for thyroid and parathyroid surgery. Several variations of transoral access to the anterior neck areas were applied in recent years. One of them is a premandibular access proposed by Nakajo et al, it is performed through the oral vestibule by creating the working space by means of the lifting method. MATERIALS AND METHODS: Nineteen unfixed human cadavers were used to develop the endoscopic access to the thyroid gland and surgical techniques of its resection...
January 25, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29359990/dexmedetomidine-and-magnesium-sulfate-a-good-combination-treatment-for-acute-lung-injury
#20
Abdulmenap Güzel, Erdal Doğan, Gül Türkçü, Mahir Kuyumcu, İbrahim Kaplan, Feyzi Çelik, Zeynep Baysal Yıldırım
OBJECTIVES: In this study, we aimed to investigate the therapeutic effects of magnesium sulfate (MgSO4) and dexmedetomidine (dex) in a model of acute lung injury (ALI). We determined whether concomitant administration decreased the inflammatory effects of hydrochloric acid (HCl)-induced ALI in a synergistic manner. MATERIALS AND METHODS: In this study, 42 Sprague-Dawley rats were randomized into six groups: Group S (saline), Group SV (saline + mechanical ventilation), Group HCl (HCl), Group Dex (Dex), Group Mag (MgSO4), and Group DM (Dex + MgSO4)...
January 23, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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