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Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research

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https://www.readbyqxmd.com/read/28525292/comparison-of-adjacent-segment-degeneration-after-nonrigid-fixation-system-and-posterior-lumbar-interbody-fusion-for-single-level-lumbar-disc-herniation-a-new-method-of-mri-analysis-of-lumbar-nucleus-pulposus-volume
#1
Shaofeng Yang, Yanan Liu, Zhaohua Bao, Jun Zou, Huilin Yang
PURPOSE: To evaluate the influence of a nonrigid fixation system and posterior lumbar interbody fusion on adjacent intervertebral disc degeneration by using MRI analysis of lumbar nucleus pulposus volume for single-level lumbar disc herniation. MATERIALS AND METHODS: We selected 112 patients who underwent nonrigid fixation (17 men and 44 women) or posterior lumbar interbody fusion (13 men and 38 women) for this retrospective study. Based on the T2-weighted magnetic resonance imaging (MRI) scans taken preoperatively, and 6, 12, and 24 months after surgery, the nucleus pulposus in the upper segments of the operated level was considered an ellipsoid, and their volumes were measured respectively and then compared between the two groups...
May 19, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28525290/brief-commentary-on-the-article-a-novel-clinical-simulated-suture-education-for-basic-surgical-skill-suture-on-the-biological-tissue-fixed-on-standardized-patient-evaluated-with-objective-structured-assessment-of-technical-skill-osats-tools
#2
Meer M Chisthi
No abstract text is available yet for this article.
May 19, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28498785/laparoscopic-adrenalectomy-for-conn-s-syndrome-is-beneficial-to-patients-and-is-cost-effective-in-england
#3
Ioannis Christakis, John A Livesey, Gregory P Sadler, Radu Mihai
PURPOSE: Adrenalectomy has the potential to cure or improve the control of hypertension in patients with primary hyperaldosteronism due to unilateral adrenal adenoma (Conn's syndrome). This study assesses the patients' perception of, and costs associated with, laparoscopic adrenalectomy for Conn's syndrome. MATERIALS AND METHODS: Clinical, radiological, operative, and pathological data were collected on patients undergoing adrenalectomy for Conn's syndrome over 8-years period in a UK tertiary referral center...
May 12, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28485994/copious-irrigation-versus-suction-alone-during-laparoscopic-appendectomy-for-complicated-appendicitis-in-adults
#4
Fengbo Sun, He Wang, Fengjuan Zhang, Xinming Zhang, Zhiyuan Xing, Shenglin Zhang, Haifeng Zhang, Ye Wang
OBJECTIVE: The objective of this study was to determine whether copious irrigation of peritoneal cavity during laparoscopic appendectomy for complicated appendicitis effectively reduces the incidence of postoperative complications and improves the postoperative recovery in adults compared with suction alone. METHODS: In this prospective randomized trial, adult patients with complicated appendicitis were randomized to "irrigation and suction"(IS) group or "suction only"(SO) group...
May 9, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28485991/prevention-of-fat-embolism-in-fat-injection-for-gluteal-augmentation-anatomic-study-in-fresh-cadavers
#5
Guillermo Ramos-Gallardo, David Orozco-Rentería, Pablo Medina-Zamora, Eduardo Mota-Fonseca, Leonel García-Benavides, Jesus Cuenca-Pardo, Livia Contreras-Bulnes, Ana Rosa Ambriz-Plasencia, Jesus Aaron Curiel-Beltran
INTRODUCTION: Liposuction is a popular surgical procedure. As in any surgery, there are risks and complications, especially when combined with fat injection. Case reports of fat embolism have described a possible explanation as the puncture and tear of gluteal vessels during the procedure, especially when a deep injection is planned. METHODS: A total of 10 dissections were performed in five fresh cadavers. Each buttocks was divided into four quadrants. We focused on the location where the gluteal vessels enter the muscle and the diameter of the vessels...
May 9, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28481635/heterotopic-implantation-of-decellularized-pulmonary-artery-homografts-in-a-rodent-model-technique-description-and-preliminary-report
#6
Arben Dedja, Massimo A Padalino, Mila Della Barbera, Cosimo Rasola, Paola Pesce, Anna Milan, Michela Pozzobon, David Sacerdoti, Gaetano Thiene, Giovanni Stellin
PURPOSE: Despite a substantial amount of literature on tissue-guided regeneration, decellularization process, repopulation time points and stem cell turnover, more in-depth study on the argument is required. Currently, there are plenty of reports involving large animals, as well as clinical studies facing cardiac repair with decellularized homografts, but no exhaustive rodent models are described. The purpose of this study was to develop such a model in rats; preliminary results are also herein reported...
May 8, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28441066/continued-care-in-palliative-bowel-surgery-an-invited-brief-commentary-on-long-term-functional-outcome-after-internal-delorme-s-procedure-for-obstructed-defecation-syndrome-and-the-role-of-post-operative-rehabilitation
#7
Dorian A Bogdanovski, Zoltan H Nemeth
No abstract text is available yet for this article.
April 25, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28441065/the-effect-of-sterilization-methods-of-endoscopic-instruments-on-the-body-a-study-on-rat-model
#8
Adnan Hut, Dogan Yildirim, Turgut Donmez, Cihad Tatar, Semih Mirapoglu, Rukiye Nilgun Erdogan, Zumrut Mine Isık Saglam, Huseyin Kilincaslan
PURPOSE: Laparoscopy is widely used in many surgical areas for diagnosis and treatment. The need for sterilization of reusable instruments is an important issue. Ensuring patient safety, preventing infection, and protecting the functionality of the instruments are the most important points to be considered. We aimed to investigate two sterilization methods and their effects generated by their distribution into intra-abdominal tissues during insufflation. MATERIALS AND METHODS: 21 rats were used in the study...
April 25, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28418711/silibinin-improves-tnf-%C3%AE-and-m30-expression-and-histological-parameters-in-rat-kidneys-after-hepatic-ischemia-reperfusion
#9
Georgios Kyriakopoulos, Alexandra K Tsaroucha, Georgia Valsami, Maria Lambropoulou, Nikolaos Kostomitsopoulos, Eirini Christodoulou, Zacharias Kakazanis, Constantinos Anagnostopoulos, Christos Tsalikidis, Constantinos E Simopoulos
BACKGROUND: Remote kidney damage is a sequel of hepatic ischemia-reperfusion (I/R) injury. Silibinin is the main ingredient of the milk thistle plant seed extract with known antioxidant and hepatoprotective activity. Our study investigates the nephroprotective potential of intravenously administered silibinin, as a lyophilized SLB-hydoxypropyl-beta-cyclodextrin product, in hepatic I/R injury. MATERIAL AND METHODS: 63 Wistar rats were divided into three groups: Sham (virtual intervention); Control (45 min ischemia and reperfusion); and Silibinin (200 μL intravenous silibinin administration after 45 min of ischemia)...
April 18, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28414565/new-regenerative-vascular-grafts-for-hemodialysis-access-evaluation-of-a-preclinical-animal-model
#10
Karen Tatiana Valencia Rivero, Juliana Jaramillo Escobar, Sergio David Galvis Forero, Maria Clara Miranda Saldaña, Rocío Del Pilar López Panqueva, Néstor Fernando Sandoval Reyes, Juan Carlos Briceño Triana
The purpose of this study was to evaluate a suitable animal model for the in vivo evaluation of patency and vascular tissue regeneration in small intestinal submucosa (SIS) vascular grafts for hemodialysis access. First, a 4-mm U-shaped SIS vascular graft was implanted between the internal carotid artery (CA) and the external jugular vein (JV) in five sheep and six swine. The U-shape grafts remained functional for 53 ± 4 days in sheep and 32 ± 2 days in swine. The sheep model presented exaggerated inflammation, so the swine model was selected for the in vivo study...
April 17, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28402715/protective-effect-of-cordycepin-on-experimental-testicular-ischemia-reperfusion-injury-in-rats
#11
Mehmet Hanifi Okur, Serkan Arslan, Bahattin Aydogdu, Hikmet Zeytun, Erol Basuguy, Mehmet Serif Arslan, Ibrahim Ibiloglu, Ibrahim Kaplan
OBJECTIVE: To investigate the role of cordycepin in testicular ischemia/reperfusion injury in rats. MATERIALS AND METHODS: Forty Wistar albino rats were randomly divided into four groups, as follows: group one, control (C); group two, torsion and ischemia (I); group three: detorsion with ischemia-reperfusion (IR); and group four, detorsion/cordycepin. The rats were then analyzed macromorphologically and histopathologically, and blood tests were performed. Specifically, the total oxidant status (TOS) and total antioxidant status (TAS) were determined, and malondialdehyde (MDA), tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-1β levels were analyzed...
April 12, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28402702/comparison-of-the-tight-rope-technique-and-clavicular-hook-plate-for-the-treatment-of-rockwood-type-iii-acromioclavicular-joint-dislocation
#12
Leyi Cai, Te Wang, Di Lu, Wei Hu, Jianjun Hong, Hua Chen
AIM: Acromioclavicular joint dislocation is one of the most common shoulder problems and may lead to instability or degenerative changes. The aim of this study was to compare the clinical outcomes of the Tight Rope system and clavicular hook plate for Rockwood type III acromioclavicular joint dislocation in adults. MATERIALS AND METHODS: This was a prospective, randomized study in a hospital setting. From January 2012 to December 2014, 69 patients with type III injury were reviewed...
April 12, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28402690/reduction-of-abdominal-adhesions-with-elecrospun-fiber-membranes-in-rat-models
#13
Junsheng Li, Guanghui Ren, Weiyu Zhang
PURPOSE: The aim of this study was to assess the effects three electrospun fiber membranes on postoperative adhesion formation in rat surgical models. MATERIALS AND METHODS: The PEG-PHBV (polyethylene glycol and poly-β-hydroxybutyrate valerate), PLA(Polylactic acid) and CS-PEG(chitosan and polyethylene glycol) were used for submicrometric membranes fabrication by electrospinning. A total of 64 SD male rats were randomly divided into 4 groups, one control group and 3 treatment groups, each consisting of 16 rats...
April 12, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28387579/surgical-technique-laparoscopic-gastric-sleeve-resection-in-super-obese-patients
#14
M Ilic, S S Putnik
Laparoscopic gastric sleeve (LGS) resection in super-obese patients (BMI > 50 kg/m(2)) is a challenging procedure. We have developed a unique approach and technique for LGS with no buttress stapling and without oversewing. After 102 operations there have been no leaks and late complications.
April 7, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28375035/the-effects-of-intraoperative-esmolol-infusion-on-the-postoperative-pain-and-hemodynamic-stability-after-rhinoplasty
#15
Sepideh Vahabi, Yaser Rafieian, Abolfazl Abbas Zadeh
BACKGROUND: Esmolol an ultrashort acting cardioselective β1-adrenergic receptor antagonist), has been successfully employed for perioperative sympatholysis. In this study, we tested the hypothesis that perioperative esmolol administration resulted in decreased postoperative pain and improves the hemodynamic balance in patients with rhinoplasty. METHODS: In this clinical trial study, fifty-six patients (56) undergoing rhinoplasty surgery were randomly distributed into two groups (Group E and Group C)...
April 4, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28362517/long-term-functional-outcome-after-internal-delorme-s-procedure-for-obstructed-defecation-syndrome-and-the-role-of-postoperative-rehabilitation
#16
C A Leo, P Campennì, J D Hodgkinson, P Rossitti, F Digito, G De Carli, L D'Ambrosi, P Carducci, L Seriau, G Terrosu
PURPOSE: To evaluate long-term functional outcomes of Internal Delorme's Procedure (IDP) in patients refractory to conservative treatment for Obstructed Defecation Syndrome (ODS), and to compare those who received postoperative rehabilitation with those who did not. MATERIALS AND METHODS: All patients with ODS refractory to nonoperative therapy were identified across three regional pelvic floor referral hospitals, and IDP was performed. Postoperatively selected patients received biofeedback therapy...
March 31, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28362510/apoptosis-in-primary-hyperparathyroidism
#17
Oliwia Anna Segiet, Łukasz Mielańczyk, Adam Piecuch, Marek Michalski, Szczepan Tyczyński, Marlena Brzozowa-Zasada, Mariusz Deska, Romuald Wojnicz
Primary hyperparathyroidism (PHPT) is defined by inappropriate elevation of parathormone, caused by parathyroid hyperplasia, also known as multi-gland disease (MGD), parathyroid adenoma (PA), or parathyroid carcinoma (PC). Although several studies have already been conducted, there is a lack of a definite diagnostic marker, which could unambiguously distinguish MGD from PA or PC. The accurate and prompt diagnosis has the key meaning for effective treatment and follow-up. This review paper presents the role of apoptosis in PHPT...
March 31, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28362133/intestinal-epithelial-stem-cells-distinct-behavior-after-surgical-injury-and-teduglutide-administration
#18
Beatriz P Costa, Ana C Gonçalves, Ana M Abrantes, Raquel Alves, Paulo Matafome, Raquel Seiça, Ana B Sarmento-Ribeiro, M Filomena Botelho, Francisco Castro-Sousa
BACKGROUND: Previous studies suggest that intestinal epithelial stem cells (IESC), critical drivers of homeostasis and regeneration, include two subpopulations: crypt-based columnar and "position +4" stem cells, identified by Lgr5 and Bmi1 biomarkers, respectively. Teduglutide is an enterotrophic counterpart of glucagon-like peptide 2. This study aimed to investigate the response of putative IESC to surgical injury and teduglutide administration on an animal model of intestinal resection and anastomosis...
March 31, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28362132/identifying-patients-eligible-for-a-short-hospital-stay-after-stoma-closure
#19
Charles Sabbagh, Cyril Cosse, Lionel Rebibo, Hanane Hariz, Abdennaceur Dhahri, Jean Marc Regimbeau
INTRODUCTION: The implementation of enhanced recovery programmes after elective colorectal surgery has dramatically reduced the length of stay. The objective of this study was to assess the selection of good candidates for short post-operative stay (GCSS) in the context of stoma closure. METHODS: Between January 2011 and December 2014, 222 patients were included in the present retrospective, single-center study. The primary endpoint was the proportion of GCSS. We also identified factors associated with GCSS status and built a predictive score...
March 31, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28340320/protective-effects-of-alpha-lipoic-acid-on-methotrexate-induced-oxidative-lung-injury-in-rats
#20
Huseyin Arpag, Mehmet Gül, Yusuf Aydemir, Nurhan Atilla, Birgül Yiğitcan, Tugrul Cakir, Cemal Polat, Özer Þehirli, Muhammet Sayan
OBJECTIVE: Oxidative stress is one of the major causes of methotrexate induced lung injury (MILI). Alpha-lipoic acid (ALA), which occurs naturally in human food, has antioxidative and anti-inflammatory activities. The aim of this study was to research the potential protective role of ALA on MILI in rats. METHODS: Twenty one rats were randomly subdivided into three groups: control (group I), methotrexate (MTX) treated (group II), and MTX+ALA treated (group III). Lung injury was performed with a single dose of MTX (20 mg/kg) to groups 2 and 3...
March 24, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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