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Journal of Biological Regulators and Homeostatic Agents

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https://www.readbyqxmd.com/read/29687695/correlation-between-the-reflux-finding-score-and-the-gerd-impact-scale-in-patients-with-gastroesophageal-reflux-disease
#1
M Bianchetti, S Peralta, R Nicita, S E Aragona, G Ciprandi
Gastroesophageal reflux disease (GERD) is a very common disorder. As there is no gold standard diagnostic tool, patient-based strategy is adopted in clinical practice. In this regard, there are questionnaires able to easily and rapidly assess symptom severity directly by the patient. The GERD Impact Scale (GIS) and the Reflux Symptom Index (RSI) have been validated as diagnostic tools in routine clinical care. The present study aimed to correlate RIS values with GIS scores in a large cohort of GERD patients visited at gastroenterological clinics...
April 26, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29687694/emerging-from-gastroesophageal-reflux-emerge-an-italian-survey-ii-the-viewpoint-of-the-patient
#2
M Bianchetti, S Peralta, R Nicita, S E Aragona, G Ciprandi
Gastroesophageal reflux disease (GERD) is a very common disease, as about a quarter of the Western population has GERD symptoms at least weekly and GERD is the most frequent reason for outpatient gastroenterology consultation. GERD treatment is based on proton pump inhibitor (PPI) use, but PPI may be ineffective in some patients and potentially unsafe if administered for very long time. A new medical compound (Marial®) has been introduced on the Italian market. This product contains magnesium alginate and a phytopolymer: it may be able to repair ulcer/erosion, protect mucosal tissue, and contrast acid contents...
April 26, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29687693/emerging-from-gastroesophageal-reflux-emerge-an-italian-survey-i-the-viewpoint-of-the-gastroenterologist
#3
M Bianchetti, S Peralta, R Nicita, S E Aragona, G Ciprandi
Gastroesophageal reflux disease (GERD) is defined as a “disease that develops when the reflux of stomach contents induces troublesome symptoms and/or complications”. From a therapeutic point of view, many options have been proposed, including proton pump inhibitors (PPI), antihistamines (H2- receptor antagonists), antacid chemical compounds, antireflux barrier (using alginates), prokinetics, inhibitors of gastric sphincters, protection of mucosal tissue, neuromodulators, nociceptor antagonists, lifestyle modification, and surgery...
April 26, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29687692/gastric-reflux-the-therapeutical-role-of-marial%C3%A2
#4
S E Aragona, G Mereghetti, G Ciprandi
The worldwide relevance of gastroesophageal reflux disease (GERD) has had a considerable increase in recent years. The guidelines for the diagnosis and treatment of GERD are well consolidated and continuously updated. Recently, the extra-esophageal manifestations of reflux have been considered from a multidisciplinary point of view, so the symptoms of the laryngo-pharyngeal reflux (LPR) have been precisely defined. At present, a new Medical Compound (Marial®) has the indication for the treatment of both GERD and LPR...
April 26, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29577711/il-1-haplotype-analysis-in-periodontal-disease
#5
A Ballini, S Cantore, A Dedola, L Santacroce, L Laino, M Cicciù, F Mastrangelo
Numerous studies have established statistical associations of the IL-1 gene cluster polymorphisms with various inflammatory diseases. Deriving from that, the present study was intended to determine whether single-nucleotide polymorphisms (SNPs) in these gene are also associated with periodontal disease in a Linkage disequilibrium analysis. This investigation also created two haplotype blocks, both consisting of two different SNPs. Recent theoretical analyses indicate that research with an interpretation of periodontal disease as a complex, oligogenic disorder, with IL-1 genetic variation contributes an important but not exclusive influence on disease risk...
March 26, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29577710/etiological-periodontal-treatment-with-and-without-low-level-laser-therapy-on-il-1%C3%AE-level-in-gingival-crevicular-fluid-an-in-vivo-multicentric-pilot-study
#6
F Mastrangelo, A Dedola, F Cattoni, F Ferrini, F Bova, M Tatullo, E Gherlone, L Lo Muzio
Cytokine proteins may have important roles during different human physiological and pathological processes. In the oral cavity, the bone loss and periodontal tissue pathology was related to inflammatory process activation. The aim of the present study was to assess the effects of etiological periodontal therapy with and without the use of Low Level Laser Therapy (LLLT) on clinical periodontal parameters and interleukin (IL)-1β level in gingival crevicular fluid (GCF) from chronic periodontitis (CP) patients...
March 26, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29542876/is-static-friction-affected-by-aging-and-amount-of-elastomeric-ligatures-in-orthodontic-sliding-mechanics-an-in-vitro-investigation
#7
M Portelli, A Lucchese, A Lo Giudice, A Militi, P Spinuzza, A M Bellocchio, R Nucera, S Croce, G Ghilardi, M Manuelli
In straight-wire mechanics, friction can significantly influence the forces expressed by wires. The aim of this study is to assess whether the aging and the sum of elastomeric ligatures affect the static friction during orthodontic space closure. A 0.017x 0.025-in SS was drawn throughout a 3-bracket experimental model and engaged with elastomeric ligatures. Before performing the test, the ligatures were soaked in artificial saliva for 48 hours (Group 1), 2 weeks (Group 2) and 4 weeks (Group 3); brand-new ligatures were also tested as control group (Group 4)...
March 15, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720335/iatrogenic-traumatic-optic-neuropathy-report-of-an-injury-occurring-during-a-choanal-atresia-correction-surgery-treatment
#8
D Bertossi, D Marchioni, M Manuelli, U Tacchino, G Giampaoli, I Dall'Acqua, D De Santis, G Ricciardi, L Lanaro, N Kumar, R Nocini, P F Nocini
We report the case of a 36-year-old adult male patient who came to our attention for the evaluation of a possible iatrogenic injury suffered during the surgical correction of congenital choanal atresia. This case report retraces the patient's medical history and the events lapsed in the peri-operative time analyzing if any malpractice has occurred in causing the amaurosis.
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720334/comparison-of-linear-transverse-measures-between-plaster-and-resin-printed-digital-models
#9
M Manuelli, L Huanca Ghislanzoni, M Farronato, A Martintoni, M Marcolina, A Lucchese
The aim of this study was to test for dimensional variations between plaster models recorded with alginate impression and printed 3D physical replicas from an .stl file digitized with an intra-oral scanner. Eighty arches (maxillary and mandibular) from 40 different patients were analyzed. Classic alginate impressions and digital recordings with an intraoral scanner were taken on the same day, for both arches of each patient. Digital recordings were then printed into resin models. The linear intercanine (IC) and intermolar (IM) distances were measured with a manual electronic caliper and then compared...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720333/short-term-in-vivo-evaluation-of-cellular-dna-damage-induced-by-fixed-orthodontic-appliances
#10
D De Santis, P Pancera, U Luciano, F Gelpi, G Causarano, D Formentini, M Marchiori, L Lanaro, S Sinigaglia, D Bertossi, P Faccioni, P F Nocini
Metal ions accumulate inside the epithelial cells of the oral mucosa and damage the DNA. The aim of this study was to analyze whether DNA damage and/or apoptosis also occurs after a short-term exposure to the metals of fixed orthodontic appliances. 23 subjects were enrolled in the test group and 8 patients in the control group. Analyses performed on samples of oral mucosa were cell count, cellular viability, quantification of intracellular metal concentration, comet and micronuclei tests and quantification of intracellular Glutathione (GSH)...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720332/standard-and-low-dose-cone-beam-computer-tomography-protocol-for-orthognatodontic-diagnosis-a-comparative-evaluation
#11
M Portelli, A Militi, A Lo Giudice, R Lo Giudice, R Fastuca, I Ielo, V Mongelli, G Lo Giudice, A Martintoni, M Manuelli, A Lucchese, R Nucera
Considering the diagnostic capability offered by cone-beam computed tomography (CBCT), nowadays orthodontists often use this exam for treatment planning, especially in cases of impacted teeth, maxillary ipoplasia, orthognathic surgery etc. The aim of this study was to compare the radiation doses related to a conventional CBCT setting and that of a low dose protocol, usable in orthodontic practice. The absorbed organ doses were measured using an anthropomorphic phantom loaded with thermo-luminescent dosimeters related to sensitive organs (brain, bone marrow, salivary glands, thyroid, esophagus, oral mucosa, extrathoracic airways, lymph nodes)...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720331/in-vitro-effects-of-fluoride-based-and-desensitizing-toothpastes-on-dentine-permeability
#12
A Lucchese, A Bertacci, S Zanna, S Chersoni, M Manuelli, A Visone, D Moro, G Valdrè
This study aims to evaluate the effectiveness in reducing dentine permeability of three different toothpastes comparing with a sodium fluoride one. Dentine permeability was measured by a fluid filtration system. Dentin discs were randomized in four experimental groups and treated with different commercial toothpastes, as it follows. Group A: Sensodyne® Rapid, with strontium acetate; group B: Elmex Sensitive ProfessionalTM, with arginine and 450 ppm monofluoro-phosphate; group C: Colgate Total Advanced®, with 1450 ppm NaF; group D: AZ Pro-Expert®, with 1100 ppm SnF2...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720330/cervical-vertebrae-maturation-a-blinded-trial-study
#13
A Lucchese, G Caldara, L Montebugnoli, G Ghilardi, F Toma, A Deregibus, M Manuelli
This blinded trial was conducted to analyze possible correlations between the cervical vertebrae maturation method (CVM) and the mineralization of mandibular teeth as described by Demirjian et al. (TMS). Panoramic and cephalometric radiographs of 500 orthodontic patients were analyzed by two blinded operators. TMS was utilized to analyze mineralization of second molar, second and first premolar and canine on the left side of the mandible; CVM stage was also evaluated. A blinded statistician performed statistical correlations and multiple regression analysis...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720329/effect-of-dental-care-on-the-oral-health-of-sj%C3%A3-gren%C3%A2-s-syndrome-patients
#14
A Lucchese, M Portelli, M Marcolina, P F Nocini, G Caldara, D Bertossi, C Lucchese, U Tacchino, M Manuelli
Sjögren’s syndrome (SS) is a chronic, systemic autoimmune disease affecting the exocrine glands, particularly the salivary and lacrimal glands. Xerostomia is a major feature of this syndrome and greatly affects patient quality of life. The most typical clinical signs associated with hyposalivation are dysgeusia and dysosmia, dental caries, candidiasis, periodontal disease, gland inflammation, mucositis and oral ulcers. The aims are to investigate on Plaque Index (PI) and Gingival Index (GI) before and after dental care of SS patients...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720328/evaluation-of-bacterial-flora-composition-on-teeth-and-periodontal-tissues-in-patients-in-treatment-with-rapid-palatal-expander
#15
D De Santis, P Pancera, U Luciano, F Gelpi, G Causarano, D Formentini, M Marchiori, M L Lanaro, G Puddu, S Sinigaglia, D Bertossi, P Faccioni, P F Nocini
Patients in treatment with rapid palatal expander (RPE) require professional assistance and more meticulous instructions on oral hygiene, since this appliance predisposes to gingivitis and caries. The aim of this work is to analyse the variability of the oral microbial flora found in patients in treatment with RPE with occlusal acrylic splint. It was also investigated whether the association of an antimicrobial mouthwash was useful during orthodontic treatment or whether regular and specific home oral hygiene manoeuvres were sufficient to maintain a good plaque control...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720327/effects-of-clear-aligners-on-sleep-bruxism-randomized-controlled-trial
#16
T Castroflorio, A Bargellini, A Lucchese, M Manuelli, F Casasco, G Cugliari, I Cioffi, A Deregibus
The possible effects on sleep bruxism (SB) of clear aligners in orthodontics are unknown. This study was conducted to analyze the effects of clear aligners on SB. Sixty subjects needing orthodontic treatment and affected by SB (33 m, 27 f, 20±;5 years) were enrolled in the study and randomly assigned to one of the following three groups: 20 were given clear aligners (CAT) (12 m, 8 f, 19±5 years), 20 occlusal splint (MOS) (9 m, 11 f, 22±5 years) and 20 a placebo splint (PMS) (12 m, 8 f, 24±3 years). All groups were followed for 6 consecutive months and monitored for SB with a portable electromyographic-electrocardiographic (EMG-ECG) device (Bruxoff®, OT Bioelettronica, Torino, Italy)...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720326/piezoelectric-surgery-inserts-vs-conventional-burst-a-clinical-investigation
#17
D Bertossi, R Nocini, U Luciano, P Galzignato, G Ricciardi, A Lucchese, U Tacchino, D Donadello, L Lanaro, A Gualdi, D De Santis, G Giampaoli, P F Nocini
Piezosurgery is a new technique that can be used to cut mineralized structures without damaging adjacent soft tissues. This device has a lot of advantages: reduced surgical time, blood loss, and inferior alveolar nerve injury in bimaxillary osteotomy. Fifty patients underwent different surgical operations (orthognathic surgery, traumatic surgery, reconstructive surgery, aesthetic procedures) with 7 different kind of piezosurgery inserts in a period of 8 months. The same two surgeons performed all the procedures...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720325/histological-evaluation-of-periodontal-ligament-in-human-after-orthodontic-treatment-with-piezosurgery-and-monolateral-tooth-dislocation-and-ligament-distraction-technique-a-first-morphologic-and-histologic-evaluation
#18
D Bertossi, P F Galzignato, G Conti, U Luciano, A Gualdi, C Corega, P Faccioni, D Donadello, L Lanaro, E Grendene, A Sbarbati, D De Santis, R Nocini, P F Nocini
Traditional orthodontic tooth movement is based on the concept that application of a protracted force causes alveolar bone remodelling and adaptive changes in periodontal and dental tissues. Thus, if orthodontic tooth movement is described as a biological bone reaction to orthodontic forces mediated by the periodontal ligament (PDL), this event involves a series of sophisticated signal transduction processes that allows the PDL compression with specific histologic and biomolecular modifications. However, the preservation of the integrity of the PDL is generally difficult to achieve when it is associated with a long duration of orthodontic treatment...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720324/effects-of-stannous-fluoride-on-eroded-enamel-permeability
#19
A Bertacci, A Lucchese, S Chersoni, S Zanna, M Manuelli, G Valdrè
This study aimed to evaluate the effect in vitro of a single application of a stannous fluoride- (SnF2-) containing toothpaste on eroded enamel. Forty-eight teeth were subjected to three acid treatments: 15% hydrochloric acid for 120 s (HA group); 1% citric acid (pH=4) for 180 s (CA group); 37% phosphoric acid for 30 s (PA group). They were brushed with an electric toothbrush with pressure control and 1 g of SnF2 (1100 ppm) toothpaste for 2 min. Polyether replicas of buccal enamel surfaces were obtained at baseline, after acid exposure and after brushing, gold sputtered and inspected by SEM for fluid droplets presence...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29685027/clinical-course-of-severe-colitis-a-comparison-between-crohn%C3%A2-s-disease-and-ulcerative-colitis
#20
E Sinagra, A Orlando, A Scalisi, F Mocciaro, V Criscuoli, L Oliva, S Maisano, M Giunta, F La Seta, G Solina, A G Rizzo, A Leone, G Tomasello, F Cappello, M Cottone
Few data are available about the clinical course of severe colonic Crohn’s disease (CD). The aim of this study is to describe the clinical course of severe Crohn’s colitis in a patient cohort with isolated colonic or ileocolonic CD, and to compare it with the clinical course of patients with severe ulcerative colitis (UC). Thirty-four patients with severe Crohn’s colitis were prospectively identified in our cohort of 593 consecutive hospitalized patients through evaluation of the Crohn’s Disease Activity Index score and the Harvey-Bradshaw Index...
March 2018: Journal of Biological Regulators and Homeostatic Agents
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