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Journal of Biological Regulators and Homeostatic Agents

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https://www.readbyqxmd.com/read/30656927/effect-of-cholecalciferol-on-cd3-cd25-t-cells-in-patients-with-severe-sepsis
#1
LETTER
G H Li, D H Ren, S Yu, J Chen, K Fang, Z H Li, L Cai, Z L Shi, J Y Zhang, J I Ma
Non-adherence in patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs) may lead to increased disease activity and symptoms, poorer quality of life and increased costs related to the disease treatment. The aim of this study is to determine the level of adherence to the treatment protocols of a chronic disease such as rheumatoid arthritis in the Albanian population and to investigate the predictors of adherence to medication. This is a single-center cross-sectional study in which included 125 patients diagnosed with RA recruited from the University Hospital "Mother Teresa" in Tirana, Albania from January to December 2013...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30656926/medication-adherence-among-albanian-patients-with-rheumatoid-arthritis
#2
LETTER
S Këlliçi, J Mihani, M Miraçi, M Fida, T Backa
Non-adherence in patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs) may lead to increased disease activity and symptoms, poorer quality of life and increased costs related to the disease treatment. The aim of this study is to determine the level of adherence to the treatment protocols of a chronic disease such as rheumatoid arthritis in the Albanian population and to investigate the predictors of adherence to medication. This is a single-center cross-sectional study in which included 125 patients diagnosed with RA recruited from the University Hospital "Mother Teresa" in Tirana, Albania from January to December 2013...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30656925/effect-of-glucagon-like-peptide-1-on-autophagy-of-islet-%C3%AE-cells-in-type-2-diabetic-mice-with-high-fat-diet
#3
LETTER
C Jin, L Yu, S Fang
The aim of this study was to investigate the effect of glucagon-like peptide-1 (GLP-1) on islet β-cell autophagy in mice with type 2 diabetes induced by high-fat diet and low-dose streptozotocin (STZ). Twenty-four 6-week-old male C57BL/6J mice were divided into four groups: group A (control group; 8-week low-fat diet and 8-week normal saline treatment), group B (8-week high fat diet and streptozotocin intervention as well as 8-week normal saline treatment), group C (8-week high fat diet and streptozotocin intervention as well as 2-week GLP-1 intervention), and D (8-week high fat diet and streptozotocin intervention as well as 8-week GLP-1 intervention), with six mice in each group...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30656924/mechanism-of-platelet-rich-plasma-in-promoting-bone-defect-repair
#4
LETTER
J Hu, Y Zeng, C Shen, H Sun, X Lian
The aim of work was to study the mechanism of platelet-rich plasma (PRP) in promoting the repair of lacunar bone defects in the lower extremities of rabbits. PRP was first prepared, and PRP and artificial bone were mixed into PRP gel at a ratio of 2:1. Forty-nine healthy New Zealand white rabbits were selected, and unified standard PRP was prepared using the blood collected from one of these rabbits. The other rabbits were randomly divided into two groups, a PRP group (the bone defect area was filled with PRP gel) and an artificial group (the bone defect area was filled with only artificial bone)...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30656923/delayed-enhancement-320-row-volume-multidetector-computed-tomography-for-the-assessment-of-reperfused-acute-and-old-myocardial-infarction-in-a-porcine-model
#5
LETTER
D L Guo, Z W Gong, T Zhang, L Xue, J L Tong, X Q Li
The aim of this work was to describe the rehabilitation of a superior monoedentulia by positioning a conometric connection implant and a prosthetic crown using CAD/CAM technique. Surgical steps are explained and the biological aspects of this particular morse conometrical connection are evaluated, with particular attention to the possibility of removing the crown by means of an innovative attachment hole in the abutment. This type of monoedentulia can now be solved by implant-prosthetic replacement, and the dentist must choose the most suitable implant for each individual case, the most favorable connection and the most appropriate prosthetic material with regard to bone and soft tissue biology...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30656922/implant-conometric-connection-through-innovative-prosthetic-abutment-biological-clinical-surgical-and-prosthetic-aspects
#6
LETTER
L Giannetti, E Spinas, A Murri Dello Diago, U Consolo, L Generali
The aim of this work was to describe the rehabilitation of a superior monoedentulia by positioning a conometric connection implant and a prosthetic crown using CAD/CAM technique. Surgical steps are explained and the biological aspects of this particular morse conometrical connection are evaluated, with particular attention to the possibility of removing the crown by means of an innovative attachment hole in the abutment. This type of monoedentulia can now be solved by implant-prosthetic replacement, and the dentist must choose the most suitable implant for each individual case, the most favorable connection and the most appropriate prosthetic material with regard to bone and soft tissue biology...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30656901/interleukin-1-family-cytokines-and-mast-cells-activation-and-inhibition
#7
EDITORIAL
C E Gallenga, F Pandolfi, Al Caraffa, S K Kritas, G Ronconi, E Toniato, S Martinotti, P Conti
Activated mast cells (MCs) secrete a number of compounds including pro-inflammatory and anti-inflammatory cytokines. MCs are a potential source of cytokines and chemokines which participate in allergic reactions and inflammation. MCs can be activated by IgE through its receptor FceRI, but also by Toll-like receptors and/or interleukin (IL)-1. MCs can be a target for both pro-inflammatory and anti-inflammatory cytokines. IL-1 activates MCs to release inflammatory chemical mediators, and cytokines/chemokines, an effect which can be potentially inhibited by IL-37...
January 18, 2019: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30556383/analysis-of-changes-in-hepatic-gene-expression-and-tissue-architecture-of-heart-and-kidney-in-association-with-diet-induced-obesity-in-rattus-norvegicus
#8
LETTER
T Batool, T Akhtar, A Asghar, M B Khawar, N Sheikh
Obesity is an epidemic issue associated with low-grade inflammation and in most of the cases with poor iron condition that influences nearly every community. The present research experiment was designed to inspect the consequences of obesity on the micro architecture of heart and kidney tissues as well as on the expression of mRNA of some hepatic genes like Hepcidin, Transferrin and TNF-α in association with their role in iron regulation and proinflammatory responses in the body. Two tentative groups of Rattus norvegicus (each supplied with different proportions of fat in their food) and one control group were analysed...
December 17, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30518201/short-term-effects-of-a-dietary-supplement-on-lower-urinary-tract-symptoms
#9
LETTER
V Cosentino, A Militello, G Lauria
Benign prostatic hyperplasia (BPH) is one of the most common conditions affecting men over 40 years of age, typically manifesting itself with lower urinary tract symptoms (LUTS). Recently, research interest has focused in discovering a viable nutraceutical alternative to the drugs that are currently the first line of treatment for BPH. The aim of this study was to investigate the efficacy and safety of a dietary supplement containing curcumin, beta-sitosterol and oligomeric proanthocyanidins in a group of BPH/LUTS patients...
December 6, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30378391/differential-expression-of-cyp2j2-gene-and-protein-in-camelus-dromedarius
#10
LETTER
S Kamel, M Ibrahim, E T Awad, H M A El-Hindi, S A Abdel-Aziz
CYP2J2 is a member of the cytochrome P450 superfamily. It had been described in different mammalian species; however, no studies have described this gene in Camelus dromedarius. CYP2J2 is an epoxygenase enzyme which oxidizes various fatty acids, mainly arachidonic acid, via NADPH-dependent epoxidation to generate epoxyeicosatrienoic acids (EETs). It is a multi-functional enzyme that plays crucial roles in inflammation, cancer, drug metabolism, and embryo development. It controls the water re-absorption in the kidney and maintains the blood pressure and glucose homeostasis...
October 31, 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644305/targeting-vegf-a-in-cartilage-repair-and-regeneration-state-of-the-art-and-perspectives
#11
G Vadalà, F Russo, M Musumeci, A Giacalone, R Papalia, V Denaro
Osteoarthritis (OA) is the most common joint disorders in western populations, and is characterized by a progressive degradation of articular cartilage (AC) leading to loss of joint function. Methods to cure, delay or prevent the onset of OA and/or improve AC repair strategies have high clinical and socioeconomic impact. Possible innovative strategies envisioned for early OA treatments or cartilage repair include the implantation/injection of mesenchymal progenitors (MPs)-based constructs or cell-free bioactive scaffolds/hydrogel coupled with the controlled recruitment and instruction of resident MPs or AC...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644304/treatment-of-vancouver-b1-c-periprosthetic-hip-fractures-with-periprosthetic-polyaxial-locking-plate-system-a-3-year-follow-up
#12
A Castelli, S M P Rossi, L Rocca, E Jannelli, F Benazzo
The incidence of periprosthetic fractures after primary knee and hip arthroplasty is around 2.5% and is increasing after revision surgery up to 4%. Management of these fractures is often particularly demanding and expensive. The primary aim of the presented study is to describe our experience in using a precontoured periarticular polyaxial standard plating system in a cohort of patients with homogeneous fracture type (Vancouver B1, C), comparing our experience with other surgical solutions. In stable implants, the primary strategies aim for fracture stabilization, leaving the original prosthesis in place...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644303/total-hip-arthroplasty-in-rapidly-progressive-osteoarthritis-of-the-hip-clinical-and-radiological-outcome-of-a-consecutive-series-of-patients
#13
T Chompoosang, R D'Apolito, C Lacagnina, G Peretti, L Zagra
Rapidly progressive osteoarthritis (RPOA) is an uncommon subset of osteoarthritis (OA) characterized by rapid joint degeneration and destruction. The treatment of choice for these patients has traditionally been total hip arthroplasty (THA) because nonoperative treatments modalities are not effective. RPOA can lead to acetabular bone loss and consequently intraoperative technical difficulties making joint reconstruction in such patients a challenge for the surgeon. The purpose of this study was to determine the clinical and radiological results of patients suffering from RPOA and treated with hybrid or cementless THA at a single institution...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644302/evaluation-of-the-use-of-autologous-micro-fragmented-adipose-tissue-in-the-treatment-of-knee-osteoarthritis-preliminary-results-of-a-randomized-controlled-trial
#14
G M Perretti, M Ulivi, L De Girolamo, V Meroni, M D Lombardo, L Mangiavini
Articular cartilage injuries are still unsolved due to the limited intrinsic healing potential of this tissue. Unlike other tissues, inflammation in the synovial joint causes perpetual damage and progressively leads to the development of osteoarthritis. Previous in vitro and in vivo studies have demonstrated the efficacy of mesenchymal stem cells isolated from adipose tissue in modulating inflammation. In this study, we analyzed the role of these cells in modifying the pathological microenvironment present in knee osteoarthritis...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644301/hydatid-cyst-in-the-spine-the-alliance-between-surgeon-and-infectivologist-is-winning-a-case-report
#15
F Cuzzocrea, E Jannelli, A Ivone, R Vanelli, M Ghiara, A Fioruzzi, E Brunetti, F Benazzo
Hydatid Cyst is a protozoal disease, whose spinal localization may be cause of pain and severe inability due to neurological symptoms and instability. Treatment combines the difficulties to eradicate the cyst with the spine regional constraints. The case of a 45-year-old woman is reported, affected by hydatid cyst in the spine, submitted to combination of medical treatment and surgery (double approach gross total excision and reconstruction) and followed up for 6 years. The treatment strategy allowed an excellent quality of life without pain and neurological symptoms at the latest follow-up...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644300/how-to-obtain-better-results-choice-of-implant-or-surgical-technique-a-new-surgical-technique-with-an-extramedullary-referenced-cutting-guide-and-a-blended-alignment-method
#16
S M P Rossi, M Ghiara, A Castelli, A Ivone, E Jannelli, F Benazzo
Measured resection and ligament balancing techniques are the most used in TKA; both require, in the majority of knee arthroplasty systems, a femoral intramedullary canal referencing for the distal femoral cut. Fat embolism, activation of coagulation and bleeding may occur from the reamed canal; this can be avoided with different solutions such as navigation, patient specific instruments or the use of an extramedullary device. The FuZionTM tensor was created as a blended method with the purpose to overcome the downsides of both techniques by fusing them...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644299/the-biomolecular-interactions-between-endothelium-and-bone-cells-an-overview
#17
C Carulli, M Innocenti, F Lazzarini, M Villano, G Pasta, M L Brandi, M Innocenti
Bone turnover is a complex set of different molecules pathways and it is strictly connected with bone vasculature. It includes every bone process concerning bone modelling and remodelling such us skeletal growth and healing process. A fundamental component of this bone architecture is played by the endothelium, that acts in a paracrine fashion on other bone stromal cells via humoral factors, growth factors and chemokines/cytokines. The alteration of those biochemical interactions between endothelium, vasculature and bone tissue may cause various pathological manifestations...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644298/transiliosacral-fixation-using-the-o-arm2%C3%A2-and-stealthstation%C3%A2-navigation-system
#18
F Liuzza, L Capasso, M Florio, F Mocini, G Masci, G Cazzato, G Ciolli, N Silluzio, G Maccauro
Pelvic fractures are quite uncommon, they represent only 2-8% of all fractures. Osteosynthesis with percutaneous trans-Iliosacral screw is recognized as one of the standard procedures for the treatment of unstable posterior pelvic ring lesions. Because of the high number of complications associated with the conservative treatment of these kind of lesions such as pain, limb heterometry, difficulty in walking and sexual disability, percutaneous fixation with trans-iliosacral screw has found wide use and has become very popular among orthopedic surgeons...
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644297/mueller-weiss-disease-review-of-the-literature
#19
C Perisano, T Greco, R Vitiello, G Maccauro, F Liuzza, F C Tamburelli, F Forconi
Müller-Weiss (MW) disease is a spontaneous osteonecrosis of the tarsal navicular bone in adults. It is a rare cause of chronic medial midfoot pain and deformity characterized by the collapse of the dorso-lateral part of the navicular, progressive navicular fragmentation and talonavicular joint destruction. This study provides a review of the literature about the epidemiology, etio-pathogenesis, clinical, radiological findings and therapeutic alternatives.
November 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/30644296/secondary-femur-fracture-following-treatment-with-anterograde-nailing-the-state-of-the-art
#20
G Cazzato, G Masci, F Liuzza, L Capasso, M Florio, C Perisano, R Vitiello, G Ciolli, G Maccauro
Cephalomedullary nailing (CMN) currently represents the best surgical technique for the treatment of intertrochanteric hip fractures. Although the success of CMN in terms of functional recovery and fracture healing, in clinical practice there are many complications. Later femur fracture following treatment of trochanteric fracture with CMN is not a very frequent complication but, when it occurs, its treatment is the most complex, because of the increase of peri-operative mortality. There are studies in literature, which have demonstrated that the incidence of this complication is about 0...
November 2018: Journal of Biological Regulators and Homeostatic Agents
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