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Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus

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https://www.readbyqxmd.com/read/29757360/decision-analysis-supports-the-use-of-drain-amylase-based-enhanced-recovery-method-after-esophagectomy
#1
B Jiang, V P Ho, J Ginsberg, S J Fu, Y Perry, L Argote-Greene, P A Linden, C W Towe
Postesophagectomy anastomotic leak is a common postsurgical complication. The current standard method of detecting leak is esophagram usually late in the postoperative period. Perianastomotic drain amylase level had shown promising results in early detection anastomosis leak. Previous studies have shown that postoperative day 4 amylase level is more specific and sensitive than esophagram. The purpose of this study is to determine if implementing a drain amylase-based screening method for anastomotic leak can reduce length of stay and hospital cost relative to a traditional esophagram-based pathway...
May 10, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29757356/developing-a-diagnostic-understanding-of-gerd-phenotypes-through-the-analysis-of-levels-of-mucosal-injury-immune-activation-and-psychological-comorbidity
#2
C Zhong, K Liu, K Wang, H Liu, H Su, J Wu, L Duan
Patients with gastroesophageal reflux disease (GERD) can present with typical or atypical symptoms. The aim of this study is to explore the underlying physiological and psychological mechanisms that lead to different symptomatic manifestations of GERD. A total of 238 patients diagnosed with GERD underwent gastroscopy, 24 h multichannel intraluminal impedance-pH (MII-pH) monitoring, and psychological assessment with questionnaires. Patient symptoms were used to classify GERD into phenotypes of typical reflux syndrome (TRS, n = 87), reflux chest pain syndrome (RCS, n = 98), and extraesophageal syndromes (EES, n = 53)...
May 10, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29757350/implementation-of-guidelines-in-eosinophilic-esophagitis-at-an-academic-pediatric-practice
#3
Brendan R Harris, Emily Hon, Sandeep K Gupta
Guidelines for eosinophilic esophagitis (EoE) require high-dose PPI (HD-PPI) trial to evaluate for PPI-responsive esophageal eosinophilia (PPI-REE) prior to EoE diagnosis and dedicated therapy. This involves a second esophagogastroduodenoscopy (EGD) to assess for PPI-REE. This study is to evaluate adherence to current guidelines in evaluation of PPI-REE and EoE. Retrospective review of new patients treated with HD-PPI after an index EGD showing >15 eos/hpf in esophageal biopsies. One hundred and eighty patients had an index EGD with esophageal eosinophilia of >15 eos/hpf...
May 10, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29718161/outcome-of-long-benign-esophageal-strictures-undergoing-endoscopictherapy-a-tertiary-center-experience
#4
M Pang, M J Bartel, E C Brand, B Brahmbhatt, K Patel, C R Simons-Linares, H C Wolfsen, M Raimondo, M B Wallace, T A Woodward
Complex benign esophageal strictures are defined by length (≥2 cm), small diameter, and stricture angulation or tortuosity. The long-term course of complex esophageal strictures based on length is currently unclear. We suspect that the esophageal stricture length might impact the effectiveness of endoscopic dilation therapy. We performed a retrospective study of all benign esophageal strictures of 2 cm or longer treated at a single center between July 1, 2010, and May 31, 2014. Primary outcomes were changed in dysphagia score at the end of follow-up compared to first dilation at our facility and the need for gastrostomy placement or esophagectomy during follow-up...
May 1, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29718160/safety-and-feasibility-of-robotic-assisted-ivor-lewis-esophagectomy
#5
K Meredith, J Huston, O Andacoglu, R Shridhar
Esophagectomy is associated with substantial morbidity. Robotic surgery allows complex resections to be performed with potential benefits over conventional techniques. We applied this technology to transthoracic esophagectomy to assess safety, feasibility, and reliability of this technology. A retrospective cohort study of all patients undergoing robotic-assisted Ivor-Lewis esophagectomy (RAIL) from 2009 to 2014 was conducted. Clinicopathologic factors and surgical outcomes were recorded and compared. All statistical tests were two-sided and a P-value of <0...
May 1, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29701761/size-of-recurrent-laryngeal-nerve-as-a-new-risk-factor-for-postoperative-vocal-cord-paralysis
#6
Y Saito, H Takeuchi, K Fukuda, K Suda, R Nakamura, N Wada, H Kawakubo, Y Kitagawa
Recurrent laryngeal nerve paralysis (RLNP) is a frequent and serious complication following esophageal cancer surgery. Therefore, this study aims to evaluate the correlation between recurrent laryngeal nerve (RLN) size and RLNP. This was a retrospective study of esophageal cancer patients who underwent thoracoscopic esophagectomy from January 2012 to December 2014. Eighty-four patients were included in the primary analysis. Diameter of the RLN was measured using the digital video recording of surgical procedures by the ratio between scissor and RLN...
April 26, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29701760/optical-techniques-for-perfusion-monitoring-of-the-gastric-tube-after-esophagectomy-a-review-of-technologies-and-thresholds
#7
S M Jansen, D M de Bruin, M I van Berge Henegouwen, S D Strackee, D P Veelo, T G van Leeuwen, S S Gisbertz
Anastomotic leakage is one of the most severe complications after esophageal resection with gastric tube reconstruction. Impaired perfusion of the gastric fundus is seen as the main contributing factor for this complication. Optical modalities show potential in recognizing compromised perfusion in real time, when ischemia is still reversible. This review provides an overview of optical techniques with the aim to evaluate the (1) quantitative measurement of change in perfusion in gastric tube reconstruction and (2) to test which parameters are the most predictive for anastomotic leakage...
April 26, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29668913/defining-pneumonia-after-esophagectomy-for-cancer-validation-of-the-uniform-pneumonia-score-in-a-high-volume-center-in-north-america
#8
M F J Seesing, A Wirsching, P S N van Rossum, T J Weijs, J P Ruurda, R van Hillegersberg, D E Low
Surgery is a central component of multimodality therapy for esophageal and gastroesophageal junction cancer. Pneumonia is a common sequela of esophagectomy, leading to an increase in intensive care unit stay, hospital stay, readmission rates, and postoperative mortality. Developing strategies to reduce pneumonia after esophagectomy is hampered by the absence of a standardized methodology for defining pneumonia. This study aims to validate the Uniform Pneumonia Score (UPS) in a high volume center in the USA...
April 14, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29668925/postoperative-pain-management-after-esophagectomy-a-systematic-review-and-meta-analysis
#9
E Visser, M Marsman, P S N van Rossum, E Cheong, K Al-Naimi, W A van Klei, J P Ruurda, R van Hillegersberg
No abstract text is available yet for this article.
April 13, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29668909/effect-of-ephedrine-on-gastric-conduit-perfusion-measured-by-laser-speckle-contrast-imaging-after-esophagectomy-a-prospective-in-vivo-cohort-study
#10
S M Jansen, D M de Bruin, M I van Berge Henegouwen, P R Bloemen, S D Strackee, D P Veelo, T G van Leeuwen, S S Gisbertz
Compromised perfusion due to ligation of arteries and veins in esophagectomy with gastric tube reconstruction often (5-20%) results in necrosis and anastomotic leakage, which relate to high morbidity and mortality (3-4%). Ephedrine is used widely in anesthesia to treat intraoperative hypotension and may improve perfusion by the increase of cardiac output and mean arterial pressure (MAP). This study tests the effect of ephedrine on perfusion of the future anastomotic site of the gastric conduit, measured by laser speckle contrast imaging (LSCI)...
April 13, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29668906/learning-curve-for-robotic-esophagectomy-and-dissection-of-bilateral-recurrent-laryngeal-nerve-nodes-for-esophageal-cancer
#11
S Y Park, D J Kim, D R Kang, S J Haam
No abstract text is available yet for this article.
April 13, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29635420/validation-of-a-biomarker-panel-in-barrett-s-esophagus-to-predict-progression-to-esophageal-adenocarcinoma
#12
S Eluri, E Klaver, L C Duits, S A Jackson, J J Bergman, N J Shaheen
In a prior study, baseline mutational load (ML) predicted progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) in Barrett's esophagus (BE) with an area under the curve (AUC) of 0.95. We aimed to validate the test characteristics of this predictive biomarker panel using crude DNA lysates in a larger well-characterized cohort. We performed a nested case-control study of BE patients from three tertiary referral centers in the Netherlands. Cases had baseline nondysplastic BE (NDBE) and developed HGD/EAC ≥ 2 years later...
April 3, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29635398/the-predictive-value-of-new-onset-atrial-fibrillation-on-postoperative-morbidity-after-esophagectomy
#13
M F J Seesing, J C G Scheijmans, A S Borggreve, R van Hillegersberg, J P Ruurda
New-onset atrial fibrillation (AF) is frequently observed following esophagectomy and may predict other complications. The aim of the current study was to determine the association between, and the possible predictive value of, new-onset AF and infectious complications following esophagectomy. Consecutive patients who underwent elective esophagectomy with curative intent for esophageal cancer between 2004 and 2016 in the University Medical Center Utrecht were included from a prospective database. The date of diagnosis of the complications included in the current analysis was retrospectively collected from the computerized medical record...
April 3, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29617746/thoracoabdominal-pressure-gradient-and-gastroesophageal-reflux-insights-from-lung-transplant-candidates
#14
T Masuda, S K Mittal, B Kovacs, M Smith, R Walia, J Huang, R M Bremner
Advanced lung disease is associated with gastroesophageal reflux disease (GERD). The thoracoabdominal pressure gradient (TAPG) facilitates gastroesophageal reflux, but the effects of TAPG on gastroesophageal reflux in patients with pulmonary disease have not been well defined. Patients diagnosed with end-stage lung disease are expected to have the most extreme derangement in respiratory mechanics. The aim of this study is to explore the relationship between TAPG and reflux in lung transplant (LTx) candidates...
March 31, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29617744/natural-history-of-eosinophilic-esophagitis-a-systematic-review-of-epidemiology-and-disease-course
#15
N J Shaheen, V Mukkada, C S Eichinger, H Schofield, L Todorova, G W Falk
Eosinophilic esophagitis is a chronic immune-mediated esophageal disorder. For its timely diagnosis, clinicians must recognize common symptoms, and understand differences in symptoms across patient groups. The aim of this study is to systematically review the epidemiology and natural history of eosinophilic esophagitis. The MEDLINE, Embase, and Cochrane databases were searched from 1974 to February 2017 for studies describing the epidemiology and natural history of eosinophilic esophagitis. Congress abstracts from 2014 to 2016 were also searched...
March 31, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29617798/inpatient-burden-of-esophageal-cancer-and-analysis-of-factors-affecting-in-hospital-mortality-and-length-of-stay
#16
S Sarvepalli, S K Garg, S S Sarvepalli, M P Parikh, V Wadhwa, S Jang, P N Thota, M R Sanaka
Esophageal cancer (EC) continues to be a major source of morbidity and mortality in the United States. However, there has been a relative dearth of research into hospital utilization in patients with EC. This study examines temporal trends in hospital admissions, length of stay (LOS), mortality, and costs associated with EC. In addition, we also analyzed factors associated with inpatient mortality and LOS. We interrogated National Inpatient Sample (NIS), a large registry of inpatient data, to retrieve information about various demographic and factors associated with hospital stay in patients who were admitted for EC between the years 1998 and 2013 in the United States...
March 28, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29617752/muscle-layer-thickness-affects-the-peroral-endoscopic-myotomy-procedure-complexity
#17
D Watanabe, S Tanaka, R Ariyoshi, H Abe, F Kawara, T Toyonaga
Esophageal motility disorders can cause severe dysphagia, regurgitation, and/or noncardiac chest pain due to a lack of coordinated esophageal motility function. However, the clinical significance of esophageal muscle layer thickness remains unclear. The aims of this study are to elucidate the clinical significance of esophageal muscle layer thickness in patients with esophageal motility disorders who undergo peroral endoscopic myotomy (POEM), and to identify predictors of a longer POEM procedure time. Seventy-four consecutive patients with esophageal motility disorders who underwent POEM procedures at Kobe University Hospital from April 2015 to December 2016 were prospectively recruited into this study...
March 28, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29617747/reply-to-letter-obesity-and-esophagectomy-for-esophageal-cancer-is-it-only-the-high-bmi-that-defines-prognosis
#18
O Mc Cormack, V Mengardo, F Pucetti, A Chaudry, W H Allum
No abstract text is available yet for this article.
March 28, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29617733/reflux-after-esophagectomy-with-gastric-conduit-reconstruction-in-the-posterior-mediastinum-for-esophageal-cancer-original-questionnaire-and-eortc-qlq-c30-survey
#19
Y Nakahara, M Yamasaki, Y Miyazaki, K Tanaka, T Makino, T Takahashi, Y Kurokawa, K Nakajima, S Takiguchi, M Mori, Y Doki
Reflux following an esophagectomy with gastric conduit reconstruction in the posterior mediastinum is a clinically significant problem. In this study, we investigated the frequency and impact of reflux on the quality of life (QOL) among 158 patients who underwent an esophagectomy for esophageal cancer using an original questionnaire and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Version 3.0 (EORTC QLQ-C30). Reflux frequency was assessed using the original questionnaire...
March 28, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29584815/erratum
#20
(no author information available yet)
No abstract text is available yet for this article.
March 23, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
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