journal
MENU ▼
Read by QxMD icon Read
search

Gynecological Endocrinology

journal
https://www.readbyqxmd.com/read/28102095/significance-of-the-ionized-calcium-measurement-to-assess-calcium-status-in-osteopenic-osteoporosis-postmenopausal-outpatients
#1
Letizia Guiducci, Silvia Maffei, Laura Sabatino, Luc Zyw, Debora Battaglia, Alessandro Vannucci, Pietro Di Cecco, Cristina Vassalle
INTRODUCTION: Evaluation of calcium status is important in the osteoporotic risk assessment. Although guidelines indicate total calcium (tCa) as first-line measurement, directly measured ionized calcium (m-iCa), considered as the gold standard, is more and more often required. Aim of this study is to evaluate the agreement between m-iCa, tCa and iCa calculated from a formula based on total calcium and albumin (c-iCa) in osteopenic/osteoporotic postmenopausal outpatients. METHODS: A total of 140 postmenopausal outpatients, 41 osteopenic (OPN) and 99 osteoporotic (OP) were enrolled...
January 19, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28102091/obesity-related-insulin-resistance-in-adolescents-a-systematic-review-and-meta-analysis-of-observational-studies
#2
P Thota, F R Perez-Lopez, V A Benites-Zapata, V Pasupuleti, A V Hernandez
Insulin resistance is common among obese adolescents; however, the extent of this problem is not clear. We conducted a systematic review of PubMed-Medline, CINAHL, The Web of Science, EMBASE and Scopus for observational studies evaluating components defining insulin resistance (insulin, C-peptide and homeostatic model assessment-insulin resistance [HOMA-IR]) in obese adolescents (12-18 years) versus non-obese adolescents. Our systematic review and meta-analysis followed the PRISMA guidelines. Data were combined using a random-effects model and summary statistics were calculated using the mean differences (MDs)...
January 19, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28102088/hyperandrogenism-in-a-postmenopausal-woman-a-rare-case-of-ectopic-adrenal-cortical-gland
#3
Antonella Guarino, Luisa Di Benedetto, Valentina Giovanale, Gian Luca Rampioni Vinciguerra, Antonella Stoppacciaro, Filippo Bellati, Donatella Caserta
Most frequent causes of androgenic manifestation are Cushing's syndrome, PCO, benign and malignant androgen-secreting non adrenal tumors and iatrogenic hirsutism. Hyperplasia or neoplasms of ectopic adrenocortical gland are rare. We report a case of a 63-year old female with hirsutism and alopecia. Laboratory data highlighted increased levels of androgens. Diagnostic imaging revealed normal morphology of adrenocortical gland and ovaries. In view of the clinical picture and suspected diagnosis of extra-adrenal cause, she underwent bilateral salpingo-oophorectomy...
January 19, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28084847/prescribing-exercise-for-prevention-and-treatment-of-gestational-diabetes-review-of-suggested-recommendations
#4
Cristina Bianchi, Lorella Battini, Michele Aragona, Cristina Lencioni, Serena Ottanelli, Matilde Romano, Maria Calabrese, Ilaria Cuccuru, Alessandra De Bellis, Mary Liana Mori, Anna Leopardi, Gigliola Sabbatini, Pietro Bottone, Roberto Miccoli, Giuseppe Trojano, Maria Giovanna Salerno, Stefano Del Prato, Alessandra Bertolotto
Exercise has been proved to be safe during pregnancy and to offer benefits for both mother and fetus; moreover, physical activity may represent a useful tool for gestational diabetes prevention and treatment. Therefore, all women in uncomplicated pregnancy should be encouraged to engage in physical activity as part of a healthy lifestyle. However, exercise in pregnancy needs a careful medical evaluation to exclude medical or obstetric contraindications to exercise, and an appropriate prescription considering frequency, intensity, type and duration of exercise, to carefully balance between potential benefits and potential harmful effects...
January 13, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28084176/obesity-is-associated-with-a-higher-prevalence-of-musculoskeletal-pain-in-middle-aged-women
#5
Juan Enrique Blümel, Eugenio Arteaga, Edward Mezones-Holguín, María Cristina Zúñiga, Silvina Witis, María Soledad Vallejo, Konstantino Tserotas, Hugo Sánchez, William Onatra, Eliana Ojeda, Desiree Mostajo, Alvaro Monterrosa, Selva Lima, Mabel Martino, Jose Alberto Hernández-Bueno, Gustavo Gómez, María Teresa Espinoza, Daniel Flores, Peter Chedraui, Andrés Calle, Luz María Bravo, Zully Benítez, Ascanio Bencosme, Germán Barón
Musculoskeletal pain (MSP) has been recently linked with high plasma leptin levels. Our objective was to study if obese women, who have higher leptin levels, could have a higher frequency of MSP. We studied 6079 Latin-American women, 40-59 years old. Their epidemiological data were recorded and the Menopause Rating Scale (MRS), Golberg Anxiety and Depression Scale and Insomnia Scale were applied. MSP was defined as a score ≥2 on MRS11. Women with MSP were slightly older, had fewer years of schooling and were more sedentary...
January 13, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28084114/results-of-a-5-year-contraceptive-trial-in-parous-and-nulliparous-women-with-a-new-lng-ius
#6
Dirk Wildemeersch, Norman D Goldstuck, Geert Jackers
OBJECTIVE: To report on the contraceptive performance and continuation of a new T-shaped LNG-IUS, releasing 20 μg of levonorgestrel/day, in both parous and nulliparous nulliparous women after 5 years of use. MATERIALS AND METHODS: An observational prospective contraceptive study conducted in parous and nulliparous women up to 48 years of age. RESULTS: The study was conducted in a sample size of 356 women of whom 67.1% were parous and 32...
January 13, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28084098/mtnr1a-and-mtnr1b-gene-polymorphisms-in-women-with-gestational-diabetes
#7
Maciej Tarnowski, Damian Malinowski, Krzysztof Safranow, Violetta Dziedziejko, Andrzej Pawlik
Gestational diabetes mellitus (GDM) is glucose intolerance detected during pregnancy. The MTNR1B gene is the genetic locus associated with type 2 diabetes, that may affect insulin secretion and pancreatic glucose sensing. In this study, we examined the association between MTNR1A (rs2119882) and MTNR1B (rs10830963, rs4753426) gene polymorphisms and the risk of GDM. According to the results of their oral glucose tolerance test (OGTT), the women were divided into two groups: 204 pregnant women with GDM and 207 pregnant women with normal glucose tolerance (NGT)...
January 13, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28079409/promoting-awareness-of-neonatal-menstruation
#8
Paola Bianchi, Giuseppe Benagiano, Ivo Brosens
Neonatal uterine bleeding (NUB) has been carefully studied in the past through case reports, small series, clinical cohort studies, pathology investigations of fetal and neonatal. Following a historical recount, this review summarizes biological mechanisms conditioning NUB, starting from the persistence till birth of an 'ontogenetic progesterone resistance' (OPR), causing decreased responsiveness of target tissues to bioavailable progesterone. Several pregnancy-related conditions, such as preeclampsia, fetal growth restriction, prematurity, post-maturity and even Rhesus or ABO incompatibility, influence the occurrence of NUB...
January 12, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28079402/sexual-dysfunction-in-premenopausal-women-could-be-related-to-hormonal-profile
#9
Fabiene Bernardes Castro Vale, Bruna Barbosa Coimbra, Gerson Pereira Lopes, Selmo Geber
Female sexual dysfunction (FSD) is a public health problem that affects women's quality of life. Although the relationship between some hormones and the FSD has been described, it is not well established for all hormones. Therefore, the aim of our study was to evaluate the association between hormonal dysfunction and sexual dysfunction in premenopausal women. We performed a cross-sectional study with 60 patients with regular menstrual cycles, with age ranging from 18 to 44 years, with previous diagnosis of FSD...
January 12, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28051891/the-relationship-between-thyroid-function-and-metabolic-changes-in-chinese-women-with-polycystic-ovary-syndrome
#10
Dongmei Yin, Xiangyan Ruan, Xuanxuan Tian, Juan Du, Yue Zhao, Yamei Cui, Yanglu Li, Alfred O Mueck
OBJECTIVES: Aim was to evaluate endocrine, metabolic and thyroid parameters which could help to explore the relationship between thyroid function and metabolic changes in Chinese polycystic ovary syndrome (PCOS) patients. METHODS: Within a prospective study in PCOS patients compared with healthy women, thyroid parameters were assessed, as well as changes of endocrine, metabolic and clinical characteristics. RESULTS: 144 PCOS patients and 48 normo-ovulatory women matched by age as controls were included...
January 4, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28051885/elevated-serum-interferon-%C3%AE-inducible-protein-10-in-women-with-polycystic-ovary-syndrome
#11
Hongli Deng, Zhibo Li, Guang Liu, Xianhua Li, Yong Chen, Yong Zhang, Yifan Sun, Jinjian Fu
BACKGROUND: Interferon γ-induced protein 10 kDa (IP10/CXCL10) is a chemokine related to endocrine disorders; however, the serum concentrations of IP10 in women with polycystic ovary syndrome (PCOS) have not yet been reported. Therefore, we investigated whether IP10 is increased in PCOS patients and its potential clinical value in PCOS patients. METHODS: For this research, the serum IP10, glucose, insulin, high sensitivity C-reactive protein (hs-CRP), follicle-stimulating hormone (FSH), luteinizing hormone (LH) and total testosterone (TT) concentrations were measured in 60 women with PCOS and healthy controls...
January 4, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28042738/mir-520-promotes-dna-damage-induced-trophoblast-cell-apoptosis-by-targeting-parp1-in-recurrent-spontaneous-abortion-rsa
#12
Xiujuan Dong, Long Yang, Hui Wang
The establishment and maintenance of successful pregnancy mainly depends on trophoblast cells. Their dysfunction has been implicated in recurrent spontaneous abortion (RSA), a major complication of pregnancy. However, the underlying mechanisms of trophoblasts dysfunction remain unclear. DNA-damage-induced cell apoptosis has been reported to play a vital role in cell death. In this study, we identified a novel microRNA (miR-520) in RSA progression via regulating trophoblast cell apoptosis. Microarray analysis showed that miR-520 was highly expressed in villus of RSA patients...
December 31, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28019139/individual-luteolysis-post-gnrh-agonist-trigger-in-gnrh-antagonist-protocols
#13
B Lawrenz, F Ruiz, N Engelmann, H M Fatemi
Over the past few years, the use of Gonadotropin-releasing-hormone (GnRH)-agonist for final oocyte maturation in GnRH-antagonist-protocols in stimulated IVF/ICSI cycles has gained worldwide acceptance, as this approach reduces significantly the risk for development of ovarian hyperstimulation syndrome (OHSS). Final oocyte maturation with GnRH-agonist leads to sever luteolysis, which cannot be counterbalanced using standard luteal phase support with purely progesterone (P4) application and therefore administration of hCG or high doses of P4 is considered to be essential to prevent/counteract luteolysis...
December 26, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28010150/repeated-doses-of-gnrh-antagonist-at-midcycle-in-artificial-frozen-embryo-transfer-cycles-may-not-affect-pregnancy-outcomes
#14
Katherine L Palmerola, Jennifer Y Hsu, Lisa C Grossman, Mark V Sauer, Roger A Lobo
No significant differences in outcomes have been found between protocols of endometrial preparation for frozen embryo transfer (FET), though gonadotropin releasing hormone (GnRH) antagonists may have detrimental effects on the endometrium. We conducted a retrospective cohort noninferiority study at a single academic center of women receiving multiple doses of mid-cycle GnRH antagonist (GAnt) to those receiving GnRH agonist (GAg) to determine if there are detrimental effects of GnRH antagonists. 1047 FET cycles were identified, detailed data was available in 840 cycles: 610 GAg and 230 GAnt cycles...
December 23, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28010148/bone-health-of-the-ovahimba-people-of-north-western-namibia-in-the-context-of-urbanization-and-a-change-of-the-sociocultural-environment
#15
Anneke Wilhelm, Peyman Hadji, Mark Münzel, Hanna Daniel, Stephan Flache, Peter Nyarango, Peter Herbert Kann
The prevalence of osteoporosis in Sub-Saharan African (SSA) countries is low, however, as urbanization takes root, it is predicted that bone health will decrease dramatically. The bone health of the semi-nomadic Ovahimba people of Namibia was investigated in the context of urbanization and changes of the sociocultural environment. Furthermore, data on bone health in SSA countries is scarce; there exists no ethnic-specific reference group for people of black origin. Included in the study were 98 urban and rural living Ovahimba people...
December 23, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28010141/differential-expression-of-visfatin-leptin-stromal-cell-derived-factor-1%C3%AE-endothelial-nitric-oxide-synthase-and-vascular-endothelial-growth-factor-in-human-leiomyomas
#16
Bo Sun Joo, Min Jung Park, Chang-Woon Kim, Kyu Sup Lee, Jong Kil Joo
AIM: This study was aimed to understand expressions of the visfatin, leptin, stromal cell derived factor (SDF)-1α, endothelial nitric oxide synthase (eNOS), and vascular endothelial growth factor (VEGF) in human uterine leiomyomas (UL) and normal myometrium. METHOD: This study investigated expression of visfatin, leptin, SDF-1α, eNOS and VEGF in 23 uterine leiomyoma patients and 10 normal myometrium by RT-PCR and western blot. Messenger RNA transcripts of SDF-1α, eNOS, VEGF and hypoxia inducible factor-1α (HIF-1α) were analyzed according to the size of UL by real-time PCR...
December 23, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28010139/association-of-serum-leptin-with-bone-mineral-density-in-postmenopausal-osteoporotic-females
#17
Saba Tariq, Mukhtiar Baig, Sundus Tariq, Muhammad Shahzad
OBJECTIVE: Present study was designed to find out whether leptin is a predictor of bone mass density (BMD) in premenopausal women (PMW) and postmenopausal osteoporotic women (PMOPW) or it has no association with BMD. METHODS: One hundred and ninety two women (98 PMOPW and 94 PMW) were recruited for this study. The control group was BMI matched with osteoporotic subjects. BMD assessment was done on calcaneus by peripheral ultrasound bone densitometry and T scores were determined...
December 23, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27960599/association-of-betatrophin-with-metabolic-characteristics-in-overweight-obese-and-lean-women-with-pcos
#18
Linxia Li, Feng Zhang, Jingjing Cui, Yu Shi, Jiangdong Xiang, Xuejiao Wang, Naisi Zhao, Qingwu Yan, Andrew S Greenberg, Yongde Peng, Xiaoying Ding
As a new hormone, betatrophin has gained attention as a potential new target to combat insulin resistance (IR) and diabetes. Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among women of the reproductive age with long term sequelae which include IR and metabolic syndrome. The aim of this study is to evaluate the circulating plasma betatrophin levels in overweight/obese or lean women with or without PCOS and also to elucidate possible correlations with anthropometric and metabolic parameters...
December 14, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27960568/altered-expression-of-hormone-receptor-integrin-%C3%AE-3-and-pinopode-in-the-endometrium-of-luteal-phase-defect-women
#19
Shuangge Liu, Teng Hua, Xiaoyan Xin, Rui Shi, Shuqi Chi, Hongbo Wang
OBJECTIVE: To invistigate estrogen receptor (ER), progesterone receptor (PR), integrin β3, and pinopode expression in luteal phase deficiency (LPD) women. METHODS: There were 52 nulligravidas consecutive infertile patients undergoing a routine assistant reproduction consultation included in this study. An endometrial biopsy sample was randomly obtained between days 4 and 10 of the luteal phase. Endometrial morphology was examined with scanning electron microscopy...
December 14, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27922279/clinical-experience-with-an-ovarian-stimulation-protocol-for-intrauterine-insemination-adopting-a-gonadotropin-releasing-hormone-antagonist-at-low-dose
#20
Adalisa Ponzano, Enrica Concetta Colangelo, Lucia Di Biase, Federica Romani, Gian Mario Tiboni
Studies testing the effectiveness of GnRH antagonists in controlled ovarian stimulation (COS) for intrauterine insemination (IUI) have provided controversial results. The present study was undertaken to evaluate, whether the use of a half of the conventional dose of the GnRH antagonist cetrorelix can be effective in increasing the successful rate of IUI cycles. Patients started COS with human menopausal gonadotropin (hMG) on day three of the menstrual cycle. Cetrorelix was started when at least one follicle of ≥14 mm, was detected at the ultrasound scan, according to the flexible multiple daily dose protocol, and continued until the trigger day with recombinant hCG...
December 6, 2016: Gynecological Endocrinology
journal
journal
29894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"