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Journal of Geriatric Psychiatry and Neurology

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https://www.readbyqxmd.com/read/28077010/positive-aspects-of-caregiving-questionnaire
#1
Ibrahim Abdollahpour, Saharnaz Nedjat, Maryam Noroozian, Yahya Salimi, Reza Majdzadeh
OBJECTIVE: The potential role of positive aspects of caregiving in enhancing caregivers' health is an important issue. The aim of this study was to develop and validate Positive Aspects of Caregiving Questionnaire (PACQ) in caregivers of patients with dementia in Iran. METHODS: Content validation process was used to content valid development. Cronbach α and intraclass correlation coefficient (ICC) were calculated as reliability indices. We used exploratory factor analysis to extract potential latent factors and evaluate the factor structure of PACQ...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28077009/cognitive-decline-body-mass-index-and-waist-circumference-in-community-dwelling-elderly-participants
#2
Jorge Mario Rodríguez-Fernández, Emily Danies, José Martínez-Ortega, William C Chen
OBJECTIVE: The aim of this study was to explore the association of body mass index (BMI), waist circumference (WC), and BMI and WC changes over time with cognitive decline in a nationally representative sample. METHODS: A total of 5239 participants (≥65 years) were followed for 3 years as part of the National Health and Aging Trends Study. Cox proportional hazard regression was applied to model the risk of cognitive decline. RESULTS: BMI, after adjusting for WC and main confounders, was associated with reduced risk of cognitive decline (hazard ratio [HR] 0...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28073327/nonmotor-symptoms-in-parkinson-disease
#3
Rosanna Palmeri, Viviana Lo Buono, Francesco Corallo, Maria Foti, Giuseppe Di Lorenzo, Placido Bramanti, Silvia Marino
Parkinson disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor symptoms. Nonmotor symptoms include cognitive deficits and impairment in emotions recognition ability associated with loss of dopaminergic neurons in the substantia nigra and with alteration in frontostriatal circuits. In this review, we analyzed the studies on social cognition ability in patients with PD. We searched on PubMed and Web of Science databases and screening references of included studied and review articles for additional citations...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28073326/hierarchical-decline-of-the-initiative-and-performance-of-complex-activities-of-daily-living-in-dementia
#4
Clarissa M Giebel, Caroline Sutcliffe, David Challis
OBJECTIVES: While basic activities of daily living hierarchically decline in dementia, little is known about the decline of individual instrumental activities of daily living (IADLs). The objective of this study was to assess initiative and performance deficits in IADLs in dementia. METHODS: A total of 581 carers completed the revised Interview for Deterioration in Daily Living Activities in Dementia 2 to rate their relative's everyday functioning. RESULTS: Initiating and performing IADLs deteriorated hierarchically, while people with dementia were consistently most impaired in initiating using the computer and managing finances...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28073325/the-moderating-role-of-insulin-like-growth-factor-1-in-the-relationship-between-cognitive-and-aerobic-endurance-change
#5
Jason R Anderson, Dayana Calvo, Ellen Glickman, John Gunstad, Mary Beth Spitznagel
BACKGROUND: Improvements in cognition often accompany fitness improvements in older adults, and research suggests insulin-like growth factor 1 (IGF-1) may influence this association. No prior work has examined this in mild cognitive impairment (MCI). We predicted that IGF-1 would moderate the relationship between cognition and aerobic endurance improvement, such that greater baseline IGF-1 would accompany a stronger relationship between cognition and aerobic endurance change. METHOD: Twenty-seven individuals with MCI completed assessments of aerobic endurance (2-minute step test [2MST]) and global cognition (Modified Mini-Mental State [3MS]) before and after a 6-month period of twice-weekly exercise...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28067106/retrospective-neuropsychological-profile-of-patients-with-parkinson-disease-prior-to-developing-visual-hallucinations
#6
Alana J Muller, Claire O'Callaghan, Courtney C Walton, James M Shine, Simon J G Lewis
Visual hallucinations (VH) are a common feature of Parkinson disease (PD); however, the cognitive profile preceding the onset of VH has not yet been established. The present study investigated longitudinal neuropsychological performance of patients with PD who developed VH during follow-up compared to a group who did not develop VH. The patient groups were matched for demographic and disease severity variables at their baseline assessments. Patients who developed VH displayed impaired performance at baseline on measures of psychomotor speed, executive functioning, reaction time, and attention compared to patients who did not develop VH...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28248559/pharmacological-and-nonpharmacological-treatment-for-apathy-in-alzheimer-disease-a-systematic-review-across-modalities
#7
Christos Theleritis, Kostas Siarkos, Everina Katirtzoglou, Antonios Politis
OBJECTIVE: Apathy is one of the most frequent neuropsychiatric symptoms encountered in Alzheimer disease (AD). Early diagnosis and timely treatment of apathy in AD seem to be of great importance, since apathy has been associated with poor disease outcome, reduced daily functioning, and caregiver distress. DESIGN: Within this context, we conducted an extensive electronic search from the databases included in the National Library of Medicine as well as PsychInfo and Google Scholar for studies that have investigated the effect of pharmacological and nonpharmacological treatments of apathy in AD...
January 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28248558/efficacy-of-vitamin-b-supplementation-on-cognition-in-elderly-patients-with-cognitive-related-diseases
#8
Dong-Mei Zhang, Jian-Xin Ye, Jun-Shan Mu, Xiao-Ping Cui
Increase in serum homocysteine is shown to be a potential risk factor for cognitive impairment. Evidence suggests that vitamin B supplementation may reduce cognitive decline by lowering the homocysteine levels. The current meta-analysis evaluated the efficacy of folic acid along with vitamin B12 and/or B6 in lowering homocysteine, thereby attenuating cognitive decline in elderly patients with Alzheimer disease or dementia. Randomized controlled trials (RCTs) comparing the efficacy of folate and B vitamin supplementation in patients with cognitive decline secondary to Alzheimer disease or dementia were identified using the keywords, "homocysteine, hyper-homocysteinemia, B vitamin, vitamin B6, B12, folic acid, cognitive, Alzheimer's disease, and dementia...
January 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28248557/the-parkinson-s-active-living-pal-program
#9
London C Butterfield, Cynthia R Cimino, Robert Salazar, Juan Sanchez-Ramos, Dawn Bowers, Michael S Okun
BACKGROUND: Apathy, one of the most common neuropsychiatric symptoms in Parkinson's disease (PD), has been associated with reduced daily functioning, cognition, treatment compliance, quality of life, and increased caregiver burden and distress, among other outcomes. OBJECTIVES: The purpose of the present study was to develop and gather pilot data on the feasibility, acceptability, and efficacy of the Parkinson's Active Living (PAL) program, to our knowledge, the first behavioral treatment specifically designed to target apathy in patients with PD...
January 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27837199/problem-gambling-in-a-sample-of-older-adult-casino-gamblers
#10
Mark van der Maas, Robert E Mann, John McCready, Flora I Matheson, Nigel E Turner, Hayley A Hamilton, Tracy Schrans, Anca Ialomiteanu
As older adults continue to make up a greater proportion of the Canadian population, it becomes more important to understand the implications that their leisure activities have for their physical and mental health. Gambling, in particular, is a form of leisure that is becoming more widely available and has important implications for the mental health and financial well-being of older adults. This study examines a large sample (2103) of casino-going Ontarian adults over the age of 55 and identifies those features of their gambling participation that are associated with problem gambling...
January 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27647793/preoperative-cognitive-performance-dominates-risk-for-delirium-among-older-adults
#11
Richard N Jones, Edward R Marcantonio, Jane S Saczynski, Douglas Tommet, Alden L Gross, Thomas G Travison, David C Alsop, Eva M Schmitt, Tamara G Fong, Sevdenur Cizginer, Mouhsin M Shafi, Alvaro Pascual-Leone, Sharon K Inouye
BACKGROUND: Cognitive impairment is a well-recognized risk factor for delirium. Our goal was to determine whether the level of cognitive performance across the nondemented cognitive ability spectrum is correlated with delirium risk and to gauge the importance of cognition relative to other known risk factors for delirium. METHODS: The Successful Aging after Elective Surgery study enrolled 566 adults aged ≥70 years scheduled for major surgery. Patients were assessed preoperatively and daily during hospitalization for the occurrence of delirium using the Confusion Assessment Method...
September 19, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27647792/risk-factors-for-cognitive-impairment-in-fragile-x-associated-tremor-ataxia-syndrome
#12
Andreea L Seritan, Kyoungmi Kim, Ian Benjamin, Ioana Seritan, Randi J Hagerman
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disease with motor, psychiatric, and cognitive manifestations that occurs in carriers of the fragile X mental retardation 1 (FMR1) gene premutations. This was a retrospective chart review of 196 individuals (127 men and 69 women) with FXTAS. Forty-six (23%) participants were cognitively impaired, of whom 19 (10%) had dementia. Risk factors for dementia were examined (CGG repeat size; alcohol, benzodiazepine, and opioid use; diabetes; hyperlipidemia; hypertension; hypothyroidism; obesity; sleep apnea; surgeries with general anesthesia; depression; family history of dementia)...
September 19, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27647791/the-frontal-assessment-battery-normative-performance-in-a-large-sample-of-older-community-dwelling-hospital-outpatient-or-general-practitioner-attenders
#13
Robert F Coen, Kevin McCarroll, Miriam Casey, Helene McNulty, Eamon Laird, Anne M Molloy, M Ward, J J Strain, Leane Hoey, Catherine Hughes, Conal J Cunningham
BACKGROUND: The Frontal Assessment Battery (FAB) is a short battery designed to assess frontal executive functioning, but data for interpretation of performance are limited. OBJECTIVES: The Trinity, Ulster, Department of Agriculture (TUDA) study provided the opportunity to derive performance data from a large sample of community-dwelling hospital outpatient or general practitioner (GP) attenders. METHODS: Normative analysis based on 2508 TUDA participants meeting these criteria: Mini-Mental State Examination (MMSE) >26/30, not depressed (Center for Epidemiologic Studies Depression <16) or anxious (Hospital Anxiety and Depression Scale <8), no history of stroke, or transient ischemic attack...
September 19, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27647790/office-based-assessment-of-at-risk-driving-in-older-adults-with-and-without-cognitive-impairment
#14
Robert A Stern, Linda M Abularach, Daniel R Seichepine, Michael L Alosco, Brandon E Gavett, Yorghos Tripodis
BACKGROUND: A multitest approach is optimal for the identification of at-risk driving among older adults. This study examined the predictive validity of a combination of office-based screening tests for on-road driving performance in older adults with and without mild cognitive impairment (MCI)/dementia. METHODS: Forty-four normal control, 20 participants with MCI, and 20 participants with dementia completed a battery of office-based assessments. On-road driving evaluation classified participants as not at-risk (n = 65) or at-risk drivers (n = 19)...
September 19, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27647789/convergent-validity-concurrent-validity-and-diagnostic-accuracy-of-the-interrai-depression-rating-scale
#15
Katherine Penny, Alex Barron, Ann-Marie Higgins, Susan Gee, Matthew Croucher, Gary Cheung
AIMS: Depression Rating Scale (DRS) is one of the clinical outcome measures of the International Resident Assessment Instrument (interRAI) assessment. The primary aim of this study is to investigate the diagnostic accuracy and concurrent validity of the 3-day assessment window version of the DRS. METHODS: The performance of DRS was compared with a gold standard clinical diagnosis of depression in 92 patients (age ≥65) who had interRAI version 9.1 Home Care assessment completed within 30 days of discharge from psychogeriatric inpatient care or memory clinic assessment...
September 19, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27647788/person-based-versus-generalized-impulsivity-disinhibition-in-frontotemporal-dementia-and-alzheimer-disease
#16
Pongsatorn Paholpak, Andrew R Carr, Joseph P Barsuglia, Robin J Barrows, Elvira Jimenez, Grace J Lee, Mario F Mendez
BACKGROUND: While much disinhibition in dementia results from generalized impulsivity, in behavioral variant frontotemporal dementia (bvFTD) disinhibition may also result from impaired social cognition. OBJECTIVE: To deconstruct disinhibition and its neural correlates in bvFTD vs. early-onset Alzheimer's disease (eAD). METHODS: Caregivers of 16 bvFTD and 21 matched-eAD patients completed the Frontal Systems Behavior Scale disinhibition items...
September 19, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27502303/update-on-vascular-dementia
#17
Ayesha Khan, Raj N Kalaria, Anne Corbett, Clive Ballard
Vascular dementia (VaD) is a major contributor to the dementia syndrome and is described as having problems with reasoning, planning, judgment, and memory caused by impaired blood flow to the brain and damage to the blood vessels resulting from events such as stroke. There are a variety of etiologies that contribute to the development of vascular cognitive impairment and VaD, and these are often associated with other dementia-related pathologies such as Alzheimer disease. The diagnosis of VaD is difficult due to the number and types of lesions and their locations in the brain...
September 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27502302/frontotemporal-dementia-an-updated-clinician-s-guide
#18
Tor Atle Rosness, Knut Engedal, Zeina Chemali
Today, frontotemporal dementia (FTD) remains one of the most common forms of early-onset dementia, that is, before the age of 65, thus posing several diagnostic challenges to clinicians since symptoms are often mistaken for psychiatric or neurological diseases causing a delay in correct diagnosis, and the majority of patients with FTD present with symptoms at ages between 50 and 60. Genetic components are established risk factors for FTD, but the influence of lifestyle, comorbidity, and environmental factors on the risk of FTD is still unclear...
September 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27502301/parkinson-disease-and-dementia
#19
Sara Garcia-Ptacek, Milica G Kramberger
Dementia is a frequent complication of Parkinson disease (PD) with a yearly incidence of around 10% of patients with PD. Lewy body pathology is the most important factor in the development of Parkinson disease dementia (PDD) and there is evidence for a synergistic effect with β-amyloid. The clinical phenotype in PDD extends beyond the dysexecutive syndrome that is often present in early PD and encompasses deficits in recognition memory, attention, and visual perception. Sleep disturbances, hallucinations, neuroleptic sensitivity, and fluctuations are often present...
September 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/27502300/imaging-in-dementia-with-lewy-bodies-an-overview
#20
Rosie Watson, Sean J Colloby
Dementia with Lewy bodies (DLB) while common in older age can present a diagnostic challenge to clinicians and is often misdiagnosed as Alzheimer disease (AD). Imaging studies have improved our understanding of the neurobiological changes in DLB during life and how they differ from AD. This has led to significant advances in the development of new techniques, such as dopaminergic imaging, which can aid the clinical diagnosis. Other functional imaging methods also show promise in helping to assess the influence of differing pathologies in DLB, most notably, AD-related and vascular pathology during life...
September 2016: Journal of Geriatric Psychiatry and Neurology
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