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Journal of Geriatric Psychiatry and Neurology

Elja van der Wolf, Susan A H van Hooren, Wim Waterink, Lilian Lechner
BACKGROUND: The gerontopsychiatric population consists of nursing home residents with combined psychiatric and physical disabilities. A validated measure to assess well-being among this population is currently not available. This article is a first step toward the development of a well-being instrument for the gerontopsychiatric population. METHODS: Potential measurement items were gathered and selected with the help of both gerontopsychiatric residents and care professionals...
May 2018: Journal of Geriatric Psychiatry and Neurology
Elizabeth Y Wang, Craig Meyer, Glenn D Graham, Mary A Whooley
BACKGROUND: Uncertainty surrounds which screening test to use in older patients with poststroke depression, in whom symptoms of depression are more complex and often occur in conjunction with other comorbidities. We evaluated screening tests for depression among a cohort of older ambulatory individuals with comorbid ischemic heart disease and prior stroke. METHODS: We administered 4 depression screening instruments to 148 participants with ischemic heart disease and self-reported stroke from The Heart and Soul Study...
May 2018: Journal of Geriatric Psychiatry and Neurology
Silvio Peluso, Anna De Rosa, Natascia De Lucia, Antonella Antenora, Maddalena Illario, Marcello Esposito, Giuseppe De Michele
Animal-assisted therapy (AAT) includes a set of nonpharmacological interventions aimed at improving human health through the use of trained or untrained animals. In recent decades, AAT has been trialed for different neurological and psychiatric disorders. In patients with dementia, interaction with animals seems to have a positive influence on aggressiveness and anxiety and to ameliorate quality of life and relationship skills. In psychiatric patients, AAT seems to increase motivation and self-esteem, improve prosocial conduct, and decrease behavioral problems...
May 2018: Journal of Geriatric Psychiatry and Neurology
Patrick M Flanigan, Mitra A Khosravi, James B Leverenz, Babak Tousi
OBJECTIVE: Dementia with Lewy bodies (DLB) is frequently misdiagnosed for Alzheimer dementia (AD), especially in its earlier stages. We characterized color vision impairment (CVI) in patients with DLB versus patients with AD to determine its usefulness in improving accuracy of early diagnosis. METHODS: We retrospectively reviewed charts of patients with AD, DLB, and patients with mild cognitive impairment suspected to be in the prodromal phase of DLB (pro-DLB) or prodromal phase of AD (pro-AD)...
March 2018: Journal of Geriatric Psychiatry and Neurology
Nathália R S Kimura, Maria Alice T Baptista, Raquel L Santos, Maria da Gloria Portugal, Aud Johannenssen, Maria L Barca, Knut Engedal, Jerson Laks, José Pedro Simões, Valeska Marinho Rodrigues, Marcia C N Dourado
BACKGROUND: Quality of life (QoL) is a growing area of interest in dementia research. This study aims to investigate the caregivers' perspective about the QoL of people with young-onset Alzheimer disease (YOAD) and late-onset Alzheimer disease (LOAD). We also aim to investigate factors that might be associated to caregivers' perspective in YOAD and LOAD. METHODS: We included 110 people with Alzheimer disease (PwAD; 53 YOAD) and their primary caregivers. The PwAD completed assessments about their QoL and cognition...
March 2018: Journal of Geriatric Psychiatry and Neurology
(no author information available yet)
Narayan SW, Jamieson HA, Nishtala PS. Evaluation of the National Minimum Data Set for Neurological Conditions in Older Adults. Journal of Geriatric Psychiatry and Neurology. 2017; 30(6):331-336. doi: 10.1177/0891988717732154 In the above-referenced article, the corresponding author's qualifications were incorrectly listed as BPharm, MPharm, PG DipClinPharm, PhD which is an overlap of another author's qualifications. The online and print versions have been updated to reflect the correct qualification of the corresponding author as BPharm, MPharmPrac...
March 2018: Journal of Geriatric Psychiatry and Neurology
Juliana Hack, Daphne Eschbach, Rene Aigner, Ludwig Oberkircher, Steffen Ruchholtz, Christopher Bliemel, Benjamin Buecking
OBJECTIVE: The aim of this study was to identify factors that are associated with cognitive decline in the long-term follow-up after hip fractures in previously nondemented patients. METHODS: A consecutive series of 402 patients with hip fractures admitted to our university hospital were analyzed. After exclusion of all patients with preexisting dementia, 266 patients were included, of which 188 could be examined 6 months after surgery. Additional to several demographic data, cognitive ability was assessed using the Mini-Mental State Examination (MMSE)...
March 2018: Journal of Geriatric Psychiatry and Neurology
Martine Paquette, Yascara Grisel Luna Saavedra, Judes Poirier, Louise Théroux, Doris Dea, Alexis Baass, Robert Dufour
BACKGROUND: Hypercholesterolemia is a major risk factor for the late-onset form of Alzheimer disease (AD). Loss-of-function (LOF) mutations of PCSK9 and PCSK9 inhibitors lower low-density lipoprotein cholesterol (LDL-C) and have been associated with a reduced risk of cardiovascular disease. The aim of this study was to examine the effect of PCSK9 LOF variants on risk and age of onset of AD. METHODS: A total of 878 participants (410 controls and 468 AD cases) from the Quebec Founder Population were included in the study...
March 2018: Journal of Geriatric Psychiatry and Neurology
Xin Xu, Cheuk Ni Kan, Tien Yin Wong, Ching-Yu Cheng, M Kamran Ikram, Christopher Li-Hsian Chen, Narayanaswamy Venketasubramanian
OBJECTIVE: Sleep disturbances were found to be associated with more behavioral and psychological symptoms (BPS) in early patients with Alzheimer's disease (AD). However, data on preclinical stages of dementia are lacking. Hence, the present study sought to investigate the association between sleep disturbances and BPS in dementia-free elderly with varying severity of cognitive impairment in an Asian sample. METHODS: Community-living elderly were recruited and administered a comprehensive cognitive battery (vascular dementia battery [VDB]) and the Neuropsychiatric Inventory to assess symptoms of sleep disturbances and BPS...
March 2018: Journal of Geriatric Psychiatry and Neurology
Manuel E Machado-Duque, Juan Pablo Castaño-Montoya, Diego A Medina-Morales, Alejandro Castro-Rodríguez, Alexandra González-Montoya, Jorge E Machado-Alba
BACKGROUND/OBJECTIVE: To determine the association between the use of anticholinergic drugs and the risk of falls with hip fracture in a population older than 60 years. METHODS: A case-control study in patients older than 60 years with a diagnosis of hip fracture. All drugs dispensed during the previous 30 days were identified. Sociodemographic, clinical, pharmacological (drugs according to the Anticholinergic Risk Scale [ARS]), and polypharmacy variables were analyzed...
March 2018: Journal of Geriatric Psychiatry and Neurology
Martinus P G Broen, A F G Leentjens, J T Hinkle, A J H Moonen, M L Kuijf, N M Fischer, K Perepezko, A Bakker, G M Pontone
OBJECTIVE: The aim of this work was to investigate marker profiles for proposed anxiety subtypes in Parkinson disease (PD). METHODS: We used the persistent anxiety, episodic anxiety, and avoidance behavior subscales of the Parkinson Anxiety Scale as dependent variables in multivariable linear regression analyses using a cross-sectional data set of 311 patients with PD. Independent variables consisted of a range of demographic, psychiatric, and disease-specific markers...
March 2018: Journal of Geriatric Psychiatry and Neurology
Elias Ghossoub, Rita Khoury
OBJECTIVES: First to explore the prevalence of criminal behavior committed by the non-institutionalized geriatric American population. Second to determine the correlates of criminal behavior among this population. METHODS: We used data of the non-institutionalized adults aged ≥65 years in the National Survey on Drug Use and Health from 2008 through 2014. We compared socio-demographic and mental health profiles of arrestees to non-arrestees and lawbreakers to non-lawbreakers and then determined the correlates of being arrested and breaking the law through regression analyses...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Takahisa Tsukada, Izumi Sato, Norihiro Matsuoka, Takumi Imai, Yuko Doi, Masaru Arai, Yosuke Fujii, Toshiyuki Matsunaga, Koji Kawakami
BACKGROUND: Antipsychotics are commonly used for managing behavioral and psychological symptoms of dementia among elderly patients with dementia receiving antidementia drugs (ADDs). However, the use of antipsychotics among these patients has not been investigated since 3 ADDs were approved in 2011 in Japan. METHOD: We conducted a descriptive study using pharmacy prescription data and identified patients aged ≥65 years who were newly prescribed donepezil, memantine, rivastigmine, and galantamine between January 1, 2012, and September 30, 2014...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Annette Hand, Lloyd L Oates, William K Gray, Richard W Walker
BACKGROUND: In the United Kingdom, people with Parkinson disease (PD) and atypical parkinsonism will require more support with their care needs as the condition progresses. There are few data on the nature of care input required and the amount of informal and formal care needed by people with PD to enable them to remain within their own home. METHOD: All people with moderate to advanced stage (Hoehn and Yahr III-V) idiopathic PD and atypical parkinsonism under the care of the Northumbria Healthcare NHS Foundation Trust PD service and living in their own home were invited to take part in The Northumbria Care Needs Project, a 10-year prospective longitudinal study...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Katrina Kalantar, Sara C LaHue, Joseph L DeRisi, Hannah A Sample, Caitlin A Contag, Scott A Josephson, Michael R Wilson, Vanja C Douglas
OBJECTIVE: To identify differences in gene expression between patients with in-hospital delirium from a known etiology (urinary tract infection [UTI]) and patients with delirium from an unknown etiology, as well as from nondelirious patients. METHODS: Thirty patients with delirium (8 with UTI) and 21 nondelirious patients (11 with UTI) were included in this prospective case-control study. Transcriptomic profiles from messenger RNA sequencing of peripheral blood were analyzed for gene expression and disease-specific pathway enrichment patterns, correcting for systemic inflammatory response syndrome...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Peijun Chen, Peter D Guarino, Maurice W Dysken, Muralidhar Pallaki, Sanjay Asthana, Maria D Llorente, Susan Love, Julia E Vertrees, Gerard D Schellenberg, Mary Sano
OBJECTIVES: To assess the prevalence of neuropsychiatric symptoms (NPS) in mild-to-moderate Alzheimer disease (AD) and their association with caregiver burden. METHODS: Secondary analyses of baseline data from the Trial of Vitamin E and Memantine in Alzheimer's Disease (TEAM-AD) (N=613). Neuropsychiatric Inventory were used to measure severity of NPS and caregiver activity survey to measure caregiver burden. RESULTS: A total of 87% of patients displayed at least 1 NPS; 70% displayed clinically meaningful NPS...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Abdullah Agit, Cafer Balci, Burcu Balam Yavuz, Eylem Cankurtaran, Mehmet Emin Kuyumcu, Meltem Halil, Servet Arıogul, Mustafa Cankurtaran
BACKGROUND: Pain is one of the most frequent symptoms in older adults. It severely impairs quality of life, increases delirium risk, and may lead to progression of dementia. Assessment of pain performed by taking anamnesis from the patient is not reliable in patients with dementia due to cooperation and communication problems. The aim of this study was to assess pain and its consequences in patients with dementia. METHODS: Seventy-five nursing home residents with dementia were enrolled...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Roseanne D Dobkin, Alejandro Interian, John Logan Durland, Michael A Gara, Matthew A Menza
High rates of depression are observed in Parkinson's disease, and limited access to care complicates management. The purpose of this pilot project was to evaluate the feasibility and impact of a personalized cognitive-behavioral telemedicine program for depression in Parkinson's disease (dPD). Thirty-four individuals with dPD and their carepartners participated in this pilot study. A 10-module self-help workbook, tailored to the unique needs of the dPD population, was created to be used as either a stand-alone intervention, with minimal therapist support, or a supplement to formal telephone-administered cognitive-behavioral therapy sessions...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Francisca S Rodriguez, Alexander Pabst, Tobias Luck, Hans-Helmut König, Matthias C Angermeyer, A Veronica Witte, Arno Villringer, Steffi G Riedel-Heller
Lack of social support has shown to be a major risk factor for poor health, mortality, and dementia. We analyzed what factors drive the likelihood of having restricted social networks and to what extent those factors then influence the risk of developing dementia. Our results from the Leipzig Longitudinal Study of the Aged (LEILA75+) indicate that older age (odds ratio [OR]: 1.04) and living with other people (OR: 2.12) was associated with a greater likelihood of having a restricted social network. A better cognitive status (OR: 0...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
Sarah Pillemer, George D Papandonatos, Cara Crook, Brian R Ott, Geoffrey Tremont
OBJECTIVE: This study aimed to compare the sensitivity and specificity of a modified version of the Minnesota Cognitive Acuity Screen (MCAS-m), by adding learning and recognition memory components, to the original version MCAS to distinguish amnestic mild cognitive impairment (aMCI) from healthy controls (HCs). METHODS/DESIGN: A total of 30 individuals with aMCI and 30 HCs underwent neuropsychological testing, neurologic examination, laboratory, and brain imaging tests...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
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