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Journal of Photochemistry and Photobiology. B, Biology

Ofentse Nobela, Ryan S Renslow, Dennis G Thomas, Sean M Colby, Sanyasi Sitha, Patrick Berka Njobeh, Louis du Preez, Fidele Tugizimana, Ntakadzeni Edwin Madala
Plants from the Asteraceae family are known to contain a wide spectrum of phytochemicals with various nutraceutical properties. One important phytochemical, chicoric acid (CA), is reported to exist in plants, such as Sonchus oleraceus and Bidens pilosa, as stereoisomers. These CA molecules occur either as the naturally abundant RR-chicoric acid (RR-CA), or the less abundant RS-chicoric acid (RS-CA), also known as meso-chicoric acid. To date, little is known about the biological activity of RS-CA, but there is evidence of its anti-human immunodeficiency virus (HIV) properties...
November 2, 2018: Journal of Photochemistry and Photobiology. B, Biology
Vahid Hoseinpour, Nasser Ghaemi
Nanobiotechnology is a promising and appearing field of nanotechnology. In recent years, the necessity of making biocompatible materials for different applications in various area such as health, medicine, water treatment and purification, etc. caused more attention to this area. Today, green synthesis of different nanoparticles (NPs) has been extensively studied. However, less attention has been paid to manganese as a high-performance metal in various applications such as medicine, biomedicine, biosensors, water treatment and purification, electronics, electrochemistry, photoelectronics, catalysis, and etc...
October 31, 2018: Journal of Photochemistry and Photobiology. B, Biology
Jaykumar Rangani, Ashok Panda, Monika Patel, Asish Kumar Parida
The facultative halophyte Salvadora persica L. grow in arid, semiarid and saline areas. In present study, drought induced alterations in growth, ion homeostasis, photosynthesis, chlorophyll fluorescence, ROS regulation and antioxidative defense components were analyzed in S. persica with an aim to elucidate the drought tolerance mechanisms. In response to drought, significant reductions in growth, photosynthesis, and photosynthetic pigments were observed in S. persica. However, leaf relative water content (RWC %) did not change significantly...
October 31, 2018: Journal of Photochemistry and Photobiology. B, Biology
N López-Marín, R Mulet, R Rodríguez
We have designed a systemic model to understand the effect of Photodynamic Therapy (PDT) on long time scales. The model takes into account cell necrosis due to oxygen reactive species, cell apoptosis through the caspase pathway and the competition between healthy and tumor cells. We attempted to describe the system using state of the art computational techniques (necrosis and apoptosis) and simple models that allow a deeper understanding of the long time scale processes involved (healing and tumor growth). We analyzed the influence of the surface and tumor depth on the effectiveness of different treatment plans and we proposed, for the set of parameters used in this work, an optimum timing between sessions of PDT...
October 30, 2018: Journal of Photochemistry and Photobiology. B, Biology
Risa Nishisaka-Nonaka, Kazuaki Mawatari, Tomomi Yamamoto, Mizuki Kojima, Takaaki Shimohata, Takashi Uebanso, Mutsumi Nakahashi, Takahiro Emoto, Masatake Akutagawa, Yohsuke Kinouchi, Takahiro Wada, Masayuki Okamoto, Hiroshi Ito, Ken-Ichi Yoshida, Tomo Daidoji, Takaaki Nakaya, Akira Takahashi
Influenza A viruses (IAVs) pose a serious global threat to humans and their livestock, especially poultry and pigs. This study aimed to investigate how to inactivate IAVs by using different ultraviolet-light-emitting diodes (UV-LEDs). We developed sterilization equipment with light-emitting diodes (LEDs) those peak wavelengths were 365 nm (UVA-LED), 310 nm (UVB-LED), and 280 nm (UVC-LED). These UV-LED irradiations decreased dose fluence-dependent plaque-forming units of IAV H1N1 subtype (A/Puerto Rico/8/1934) infected Madin-Darby canine kidney (MDCK) cells, but the inactivation efficiency of UVA-LED was significantly lower than UVB- and UVC-LED...
October 29, 2018: Journal of Photochemistry and Photobiology. B, Biology
Cheng Qian, Panshi Yan, Guangming Wan, Shenzhi Liang, Yi Dong, Jiong Wang
Drug administration by effective nano-carriers is an emerging and growing technology in the field of bio-medicine and particularly Age -related macular degeneration (AMD). This developed nanomaterials based methods with drug administration maximizes the biocompatibility and systemically increases drug delivery profile for the drugs. Herein, we described the effective drug molecules delivery profiles by the hydrothermally synthesized graphene quantum dots (GQDs) encapsulated with supramolecular β-cyclodextrin (β-CD) as a drug delivery system for AMD...
October 26, 2018: Journal of Photochemistry and Photobiology. B, Biology
S Bielfeldt, E Klette, M Rohr, B Herzog, J Grumelard, C Hanay, U Heinrich, P Hansen, D Kockott, J Lademann, C Mendrok-Edinger, S Peters, T Rudolph, T Schläger, H Tronnier, S Wiechers, L Zastrow, F Pflücker
In vitro standard methods are available and accepted worldwide to assess UVA protection of sunscreen products. Though, harmonisation of methods has made progress in the last decade, still two differing methods - one by FDA the other by ISO - are in use. In a multicentre study including 9 centres in Germany, 4 different commercial sunscreen products were assessed using both methods to discover their similarities and differences. UVA protection factor and Critical Wavelength were detected at various substrate type (sandblasted versus moulded PMMA plates), at different surface roughness of the plates as well as at different product application dose using two different irradiation spectra...
October 26, 2018: Journal of Photochemistry and Photobiology. B, Biology
Marina de M Silva, Taís S Macedo, Helena Mariana P Teixeira, Diogo Rodrigo M Moreira, Milena B P Soares, Ana Ligia da C Pereira, Vanessa de L Serafim, Francisco J B Mendonça-Júnior, Maria do Carmo A de Lima, Ricardo O de Moura, Edeildo F da Silva-Júnior, João Xavier de Araújo-Júnior, Maria Dayanne de A Dantas, Eduarda de O O Nascimento, Thamilla Maria S Maciel, Thiago Mendonça de Aquino, Isis M Figueiredo, Josué C C Santos
Acridines are considered an important class of compounds due to their wide variety of biological activities. In this work, we synthesized four acridine derivatives (1-4) and evaluated their biological activity against the Plasmodium falciparum W2 line, as well as studied the interaction with ctDNA and HSA using spectroscopic techniques and molecular docking. The acridine derivative 2 (IC50  = 0.90 ± 0.08 μM) was more effective against P. falciparum than primaquine (IC50  = 1.70 ± 0.10 μM) and similar to amsacrine (IC50  = 0...
October 19, 2018: Journal of Photochemistry and Photobiology. B, Biology
Feng Shao, AiJun Yang, Dong Mei Yu, Juan Wang, Xue Gong, Hong Xiao Tian
Bio-synthesis of nano-metal oxide particles is gaining lot of significance and recommended as promising substitute not only physical methods but also chemical methods. Here in, we demonstrate the nano-zinc oxide (nano-ZnO) particles were successfully prepared by an eco-friendly process using plant Barleria gibsoni (B. gibsoni) aqueous leaf extract. The water leaf extract of B. gibsoni responsible for not only reducing source but also protective agent. The prepared nano-ZnO particles were studied by UV-Vis diffuse reflectance (UV-DRS), Photoluminescence (PL), Fourier transform (FT-IR) infrared spectroscopy, X-ray diffraction spectroscopy (X-RD), transmission electron microscopy (TEM), thermal stability was studied by thermogravimetric and differential thermal (TG-DTA) analysis and particle size by zeta sizer, dynamic light scattering (DLS)...
October 18, 2018: Journal of Photochemistry and Photobiology. B, Biology
Yueyue Wu, Xinmei Huang, Min Yang, Jiong Xu, Zaoping Chen, Zhiyan Yu, Jun Liu
The current investigation was performed for the detailed analysis of protective effect of biofabricate berberine coated nano‑silver ameliorate (BBR-AgNPs) on acetaminophen (APAP) induced hepato-renal damages in diabetic rats by blood biochemistry, tissue biochemistry, histopathological and immunohistochemical analysis. The spherical shaped BBR-AgNPs were synthesized by the Biofabrication technique and its physico-chemical characterizations done by different spectroscopic (UV-vis spectrophotometer, XRD spectroscopy, FTIR spectroscopy EDAX & DLS analyses) and microscopic (FE-SEM) techniques...
October 17, 2018: Journal of Photochemistry and Photobiology. B, Biology
Abhijit Mukherjee, Suvranil Ghosh, Rudraditya Sarkar, Satyajit Samanta, Sudipta Ghosh, Mahadeb Pal, Adinath Majee, Sukanta Kumar Sen, Bula Singh
In the progress of small molecule as drug candidates, 4-hydroxycoumarin based compounds bearing a crucial place as potent antibiotic agents with appreciable safety in drug invention. Being synthetically and easily obtainable, 4-hydroxycoumarin related compounds with planar structure have been promoted predominantly as DNA targeting agent. Nevertheless, here we elucidate the synthesis, characterization and theoretical study of bio-active small molecule 4-hydroxy-3,4'-bichromenyl-2,2'-dione (4HBD). Then we have illuminated the binding interactions of 4HBD with calf thymus DNA (ctDNA), which is particularly designed for biological application...
October 13, 2018: Journal of Photochemistry and Photobiology. B, Biology
Alesandra Ricardo Nunes, Ana Livya Moreira Rodrigues, Dinalva Brito de Queiróz, Icaro Gusmão Pinto Vieira, João Francisco Câmara Neto, João Tavares Calixto Junior, Saulo Relison Tintino, Selene Maia de Morais, Henrique Douglas Melo Coutinho
Photooxidative damage affects cellular lipids, proteins and DNA in addition to being involved in the pathobiochemistry of erythema formation, premature skin aging, photodermatoses development and skin cancer. Phenolic compounds, flavonoids and hydroxycinnamic acid esters protect plant tissues against harmful UV-radiation. This study aimed to evaluate the sun protection factor of several Brazilian plant extracts in relation to UVB radiation absorption, which causes skin cancer, and to correlate the findings with their antioxidant activity, as well as with total phenol and flavonoid content...
October 13, 2018: Journal of Photochemistry and Photobiology. B, Biology
S Parveen, G Velmurugan, Ekkehard Sinn, P Venuvanalingam, S Govindarajan
A new class of triazine ligands (E)-2-(2-(6-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)hydrazono)propanoic acid hydrate (HL1.H2 O) and (Z)-2-(((E)-4-amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3(2H)ylidene)hydrazono)propanoic acid (H2 L2) has been synthesized by the condensation reaction of pyruvic acid with diaminoguanidine and triaminoguanidine respectively. The corresponding Schiff base cobalt complexes [Co(L1)2 ]. 2H2 O (1) and [Co(HL2)(L2)].H2 O (2) have also been synthesized and characterized by analytical, thermal, spectroscopic and diffraction studies...
October 12, 2018: Journal of Photochemistry and Photobiology. B, Biology
Dimakatso Mokoena, Sathish Sundar Dhilip Kumar, Nicolette N Houreld, Heidi Abrahamse
Wound healing is an essential process in which the separated or destroyed tissue attempts to restore itself into its normal state. In some instances, healing is prolonged and remains stagnant in the inflammatory phase, and is referred to as a chronic wound. At a cellular and molecular level, many factors are required during the process of successful wound healing, such as cytokines, polypeptide growth factors and components of the extracellular matrix (ECM). Transforming growth factor-beta (TGF-β) is considered as one of the essential growth factors in wound healing...
October 11, 2018: Journal of Photochemistry and Photobiology. B, Biology
Shahid Iqbal Farooqi, Nasima Arshad, Pervaiz Ali Channar, Fouzia Perveen, Aamer Saeed, Fayaz Ali Larik, Aneela Javeed
Two new 1,3,4-thiadiazole derivatives of ibuprofen and ciprofloxacin namely {(5-(1-(4-isobutylphenyl)ethyl)-1,3,4-thiadiazol-2-amine)} 1 and {(3-(5-amino-1,3,4-thiadiazol-2-yl)-1-cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one)} 2 were synthesized and characterized by spectroscopic and elemental analysis. DFT and molecular docking were done initially for theoretical binding possibilities of the investigated compounds. In vitro DNA binding investigations were carried out with UV-visible spectroscopic, fluorescence spectroscopic, cyclic voltammetric (CV) experiments under physiological conditions of the stomach (4...
October 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
Hussaini Majiya, Oluwapelumi O Adeyemi, Morgan Herod, Nicola J Stonehouse, Paul Millner
We recently reported the photodynamic inactivation (PDI) of bacteriophage MS2 with a photosensitiser- 5, 10, 15, 20-tetrakis (1-methyl-4-pyridinio) porphyrin- tetra- p-toluene sulfonate (TMPyP) in solution and concluded that the A-protein of the virus is the main target of inactivation. Here, we have extended these studies and carried out PDI of bacteriophage Qβ, bovine enterovirus 2 (BEV-2) and type 1 murine norovirus (MNV-1). The rate of inactivation observed was in the order MS2 > Qβ > MNV-1 > BEV-2...
October 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
Shruti Goyal, Saroj Kumar Amar, Ajeet Kumar Srivastav, Deepti Chopra, Manish Kumar Pal, Nidhi Arjaria, Ratan Singh Ray
No abstract text is available yet for this article.
October 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
P P Knox, E P Lukashev, V V Gorokhov, N Kh Seifullina, V Z Paschenko
The temperature dependence of the dark recombination rate in photooxidized bacteriochlorophyll (P) and photoreduced quinone acceptors (ubiquinones) QA and QB of photosynthetic reaction centers of purple bacteria Rhodobacter sphaeroides (Rb. sphaeroides) was studied. Photoinduced changes in the absorption were detected in the Qx absorption band of photooxidized bacteriochlorophyll at 600 nm and in the bands corresponding to the redox changes of ubiquinones at 335 and 420-450 nm. Kinetic analysis was used to evaluate the activation energy and the characteristic time of the transient process of relaxation accompanying electron stabilization at the final quinone acceptor...
October 5, 2018: Journal of Photochemistry and Photobiology. B, Biology
Camila Helena Ferreira Cuelho, Geórgia de Assis Dias Alves, Marina Ortiz Lovatto, Iuri França Bonilha, Fernanda Barbisan, Ivana Beatrice Manica da Cruz, Sara Marchesan Oliveira, Roselei Fachinetto, Gizele Scotti do Canto, Melânia Palermo Manfron
Ultraviolet B radiation represents 10% of the total UV radiation that reaches the Earth's surface, being the primary responsible for the biological effects related to skin cancer and photoaging. Ilex Paraguariensis A. St. Hil., known as Yerba mate (YM), is a native tree of South America whose polyphenols in its leaves are described to exhibit photochemoprotective effect and are employed in the treatment of cancer. Additionally, the polyphenols are used to prevent lipid peroxidation and reduce the UV-induced damage, which ultimately decreases the oxidative stress...
October 5, 2018: Journal of Photochemistry and Photobiology. B, Biology
Maki Kurata, Miyabi Hiyama, Takuma Narimatsu, Yuji Hazama, Takashi Ito, Yuhei Hayamizu, Xingping Qiu, Francoise M Winnik, Hidehumi Akiyama
Caged luciferin compounds of firefly luciferins have recently drawn much attention since firefly bioluminescence, in which D-luciferin acts as a substrate, is widely used in noninvasive gene-expression imaging, studies of in vivo cell trafficking, and the detection of enzyme activity. The objectives of this study are the development of new caged luciferins and the quantitative determination of the photophysical parameters of their photo-decomposition. We synthesized 7-(diethylaminocoumarin)-4-(yl)methyl caged D-luciferin (DEACM-caged D-luciferin) and quantitatively characterized its absorption spectrum, bioluminescence, and photoproducts using chiral HPLC chromatography, as a function of light-irradiation time...
October 5, 2018: Journal of Photochemistry and Photobiology. B, Biology
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