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Journal of Photochemistry and Photobiology. B, Biology

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https://www.readbyqxmd.com/read/29777941/characterization-of-the-binding-of-a-novel-antitumor-drug-ibrutinib-with-human-serum-albumin-insights-from-spectroscopic-calorimetric-and-docking-studies
#1
Bin Tang, Peixiao Tang, Jiawei He, Hongqin Yang, Hui Li
Ibrutinib (IBR) is a novel Bruton's tyrosine kinase inhibitor and shows good efficacy for several B-cell malignancies. In the current study, the molecular mechanism of the interaction between IBR and the transport protein human serum albumin (HSA) was ascertained by spectroscopic, calorimetric, and docking studies. Detailed investigations on affinity parameter, binding model, conformational change, and site selectivity were implemented by receptor-based and ligand-based analysis. An unusual fluorescence co-quenching (mutual quenching) was observed in the binding of IBR to HSA, followed by a static mechanism...
May 16, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29778886/perspectives-of-uv-nowcasting-to-monitor-personal-pro-health-outdoor-activities
#2
Janusz W Krzyścin, Aleksandra Lesiak, Joanna Narbutt, Piotr Sobolewski, Jakub Guzikowski
Nowcasting model for online monitoring of personal outdoor behaviour is proposed. It is envisaged that it will provide an effective e-tool used by smartphone users. The model could estimate maximum duration of safe (without erythema risk) outdoor activity. Moreover, there are options to estimate duration of sunbathing to get adequate amount of vitamin D3 and doses necessary for the antipsoriatic heliotherapy. The application requires information of starting time of sunbathing and the user's phototype. At the beginning the user will be informed of the approximate duration of sunbathing required to get the minimum erythemal dose, adequate amount of vitamin D3 , and the dose necessary for the antipsoriatic heliotherapy...
May 14, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29777942/photomodulation-multiple-sessions-as-a-promising-preventive-therapy-for-medication-related-osteonecrosis-of-the-jaws-after-tooth-extraction-in-rats
#3
Cristian Statkievicz, Luan Felipe Toro, João Martins de Mello-Neto, Daniela Pereira de Sá, Cláudio Aparecido Casatti, João Paulo Mardegan Issa, Luciano Tavares Angelo Cintra, Juliano Milanezi de Almeida, Maria José Hitomi Nagata, Valdir Gouveia Garcia, Leticia Helena Theodoro, Edilson Ervolino
The aim of this study was to evaluate the effects of photobiomodulation (PBM) with multiple sessions of low-level laser on the alveolar repair process of rats with major risk factors for medication-related osteonecrosis of the jaws (MRONJ). Senile rats received 0.45 mL of vehicle (VEH and VEH-PBM) or 0.45 mL of 100 μg/kg zoledronate (ZOL and ZOL-PBM) administrated intraperitoneally every two days during seven weeks. After three weeks of initiation of drug treatment the first lower left molar was extracted...
May 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29763757/synthesis-and-characterization-of-phytochemical-fabricated-zinc-oxide-nanoparticles-with-enhanced-antibacterial-and-catalytic-applications
#4
Jawad Ali, Rabia Irshad, Baoshan Li, Kamran Tahir, Aftab Ahmad, Muhammad Shakeel, Naeem Ullah Khan, Zia Ul Haq Khan
A "green route" to fabricate nanoparticles has emerged as a revolutionary approach. The reported work presents a green approach to synthesize ZnO nanoparticles using Conyza canadensis plant leaves extract. The synthesis of ZnO was conducted at two different temperatures i.e. 30 °C and 80 °C. ZnO nanoparticles prepared at 80 °C were smaller in size and exhibited spherical morphology. The prepared nanomaterials were examined for the reduction of organic dyes i.e. methylene blue and methyl orange...
May 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29777940/curcumin-attenuates-cerebral-ischemia-injury-in-sprague-dawley-rats-and-pc12-cells-by-suppressing-overactivated-autophagy
#5
Yan Zhang, Ming Fang, Yameng Sun, Ting Zhang, Nan Shi, Jinfeng Li, Lei Jin, Kangyong Liu, Jianliang Fu
The present study assessed whether the protective effects of curcumin against cerebral ischemia injury were due to the suppression of overactivated autophagy. Curcumin is a well-known natural polyphenolic compound that effectively counteracts oxidation, inflammation, and various types of cancer. Several studies have demonstrated the protective effects of curcumin against ischemia-reperfusion injury in tissues from the lungs, cardiomyocytes, and liver. The present study employed brain injury models induced by middle cerebral artery occlusion (MCAO) in rats and PC12 oxygen-glucose-deprived (OGD) cells...
May 7, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29763760/multispectroscopic-and-bioimaging-approach-for-the-interaction-of-rhodamine-6g-capped-gold-nanoparticles-with-bovine-serum-albumin
#6
N Manjubaashini, Mookkandi Palsamy Kesavan, Jegathalaprathaban Rajesh, T Daniel Thangadurai
Binding interaction of Bovine Serum Albumin (BSA) with newly prepared rhodamine 6G-capped gold nanoparticles (Rh6G-Au NPs) under physiological conditions (pH 7.2) was investigated by a wide range of photophysical techniques. Rh6G-Au NPs caused the static quenching of the intrinsic fluorescence of BSA that resulted from the formation of ground-state complex between BSA and Rh6G-Au NPs. The binding constant from fluorescence quenching method (Ka  = 1.04 × 104  L mol-1 ; LoD = 14.0 μM) is in accordance with apparent association constant (Kapp  = 1...
May 7, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29763759/an-eco-benign-synthesis-of-agnps-using-aqueous-extract-of-longan-fruit-peel-antiproliferative-response-against-human-breast-cancer-cell-line-mcf-7-antioxidant-and-photocatalytic-deprivation-of-methylene-blue
#7
Arif Ullah Khan, Qipeng Yuan, Zia Ul Haq Khan, Aftab Ahmad, Faheem Ullah Khan, Kamran Tahir, Muhammad Shakeel, Sadeeq Ullah
Plants mediated synthesis of noble metal nanoparticles is encountered as a clean, environment friendly, lucrative and benign loom. The current study consists of clean and green synthesis of Silver nanoparticles (AgNPs). Phytoconstituents from Longan (Euphorbia longana Lam.) fruit peel were used to reduce Ag+ into AgNPs. Different analytical techniques i.e. UV-vis Spectroscopy, X-ray diffraction spectroscopy (XRD), electron dispersive X-ray (EDX), High-resolution transmission electron microscopy (HRTEM) and Fourier transform infrared spectroscopy (FTIR) were used to analyze the synthesized AgNPs...
May 7, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29763756/tobramycin-mediated-silver-nanospheres-graphene-oxide-composite-for-synergistic-therapy-of-bacterial-infection
#8
Sadeeq Ullah, Aftab Ahmad, Fazli Subhan, Aminullah Jan, Muslim Raza, Arif Ullah Khan, Aziz-Ur Rahman, Usman Ali Khan, Muhammad Tariq, Qipeng Yuan
Graphene-based materials have attracted a significant attention in constructing hybrid systems for drug delivery with enhanced antimicrobial activities. In our work, we demonstrated the formation of silver nanoparticles (AgNPs) on graphene oxide (GO) using tobramycin (TOB), an aminoglycoside antibiotic, as reducing and decorating agent. The TOB decorated GO AgNPs (TOB-GO-Ag) composite was used as an antibacterial agent against multi-drug resistant Gram-negative E-coli (BL21 DE3). The reversal of surface potential from -30 mV (GO) to +20 mV confirms the successful reduction of GO by TOB...
May 7, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29778887/biological-potential-of-oxo-vanadium-salicylediene-amino-acid-complexes-as-cytotoxic-antimicrobial-antioxidant-and-dna-interaction
#9
Mohamed Shaker S Adam, Hany Elsawy
New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes are synthesized and characterized. They are synthesized from the reaction of sodium salicylaldehyde-5-sulfonate, some amino acids, alanine (VOHL1), leucine (VOHL2) or glycine (VOHL3) in an aqueous media, and leucine (VOHLpy1) or tryptophan (VOHLpy2) in pyridine with vanadyl acetylacetonate. The complexes are characterized by EA, TGA, IR, UV-Visible and mass spectra, conductivity and magnetic measurements. The biological activity of the VO-complexes shows that VOHL1, VOHL2 and VOHL3 exhibit anti-proliferative effect and may be used as anticancer drugs...
May 4, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29778020/eosin-y-sensitized-core-shell-tio-2-zno-nano-structured-photoanodes-for-dye-sensitized-solar-cell-applications
#10
V S Manikandan, Akshaya K Palai, Smita Mohanty, Sanjay K Nayak
In the current investigation, TiO2 and TiO2 -ZnO (core-shell) spherical nanoparticles were synthesized by simple combined hydrolysis and refluxing method. A TiO2 core nanomaterial on the shell material of ZnO was synthesized by utilizing variable ratios of ZnO. The structural characterization of TiO2 -ZnO core/shell nanoparticles were done by XRD analysis. The spherical structured morphology of the TiO2 -ZnO has been confirmed through field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) studies...
May 3, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29775919/effectiveness-of-a-flow-based-device-using-riboflavin-photochemistry-in-damaging-blood-borne-viral-nucleic-acids
#11
Liguo Zhu, Hongli Tong, Shufang Wang, Yang Yu, Zhong Liu, Changqing Li, Deqing Wang
BACKGROUND: Effectiveness of a flow-based treatment device using riboflavin photochemistry was demonstrated by cytopathic effect method using indicator viruses. However, inactivation efficacy against real blood-borne viruses needs to be evaluated, especially at nucleic acid level. MATERIAL AND METHODS: Special plasma samples with varying concentrations of blood-borne virus were selected using a strict blood selection procedure and were treated with device treatment (DT)...
May 3, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29754050/sargassum-wightii-synthesized-zno-nanoparticles-from-antibacterial-and-insecticidal-activity-to-immunostimulatory-effects-on-the-green-tiger-shrimp-penaeus-semisulcatus
#12
Ramachandran Ishwarya, Baskaralingam Vaseeharan, Suganya Subbaiah, Abdul Khudus Nazar, Marimuthu Govindarajan, Naiyf S Alharbi, Shine Kadaikunnan, Jamal M Khaled, Mohammed N Al-Anbr
The green synthesis of metal nanoparticles using phytochemical from marine seaweeds is a fast-growing research field in nanotechnology. Here, the biosynthesis of zinc oxide nanoparticles was achieved using the hot water extract of Sargassum wightii. The hot water extract prepared from S. wightii (H Sw) and ZnO NPs were studied by UV-visible and FTIR spectroscopy, SEM and XRD. Then, both products were evaluated for antibiofilm activity towards aquatic pathogens. The nanoparticles' immunostimulating potential on green tiger prawns, Penaeus semisulcatus was studied through immersion and dietary administration...
May 3, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29754049/bioluminescent-and-structural-features-of-native-folded-gaussia-luciferase
#13
Marina D Larionova, Svetlana V Markova, Eugene S Vysotski
The secreted luciferases responsible for light emission of marine copepods have gained popularity for being used in noninvasive imaging of intracellular events. The secreted luciferase of copepod Gaussia princeps is a one-subunit protein catalyzing coelenterazine oxidation to emit blue light. It consists of the N-terminal variable part that bears a signal peptide for secretion and the C-terminal catalytic domain containing ten highly conserved Cys residues supposing the existence of up to five SS bonds. Despite wide application of Gaussia luciferase in biomedical research, its biochemical properties are still insufficiently studied due to the general problem of obtaining the proper folded Cys-rich proteins in bacterial cells...
May 3, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29754048/selective-and-sensitive-fluorescent-sensor-for-pd-2-using-coumarin-460-for-real-time-and-biological-applications
#14
Bosco Christin Maria Arputham Ashwin, Gandhi Sivaraman, Thambusamy Stalin, Rathinam Yuvakkumar, Paulpandian Muthu Mareeswaran
The efficient fluorescent property of coumarin 460 (C460) is utilized to sense the Pd2+ selectively and sensitively. Fabrication of a sensor strip using commercial adhesive tape is achieved and the detection of Pd2+ is attempted using a handy UV torch. The naked eye detection in solution state using UV chamber is also attempted. The calculated high binding constant values support the strong stable complex formation of Pd2+ with C460. The detection limit up to 2.5 × 10-7  M is achieved using fluorescence spectrometer, which is considerably low from the WHO's recommendation...
May 3, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29751263/synthesis-of-zno-nanoparticles-decorated-spindle-shaped-graphene-oxide-for-application-in-synergistic-antibacterial-activity
#15
Linlin Zhong, Huifang Liu, Monica Samal, Kyusik Yun
A novel spindle-shaped graphene oxide (GO) was performed by the self-assembly of graphene oxide in the DMF. Loading uniform ZnO nanoparticles on spindle-shaped GO is used to study antibacterial property. In the ZnO/GO composites, spindle-shaped GO possessed special structure that was crumpled together with a length of ~1.0 μm and a mean diameter of 100 nm, and spherical ZnO particles with a diameter of 50 nm were fully characterized by field-emission scanning electron microscope (FE-SEM), a high-resolution transmission electron microscope (HR-TEM) and X-ray diffraction (XRD)...
May 3, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29751261/comparative-analysis-of-salt-stress-duration-and-intensity-on-the-chloroplast-ultrastructure-and-photosynthetic-apparatus-in-thellungiella-salsuginea
#16
Rahma Goussi, Arafet Manaa, Walid Derbali, Simone Cantamessa, Chedly Abdelly, Roberto Barbato
Salinity is one of the most important abiotic stress affecting plant growth and productivity worldwide. Photosynthesis, together with cell growth, is among the primary process affected by salinity. Here, we report the effects of salt stress on photosynthesis in the model halophyte Thellungiella salsuginea. Plants were grown in hydroponic system and then treated for 2 weeks with different NaCl concentrations (0, 100, 200 and 400 mM). Leaf analysis using both photonic and transmission electron microscopes showed some changes in mesophyll cell organization, including shape and dimension...
May 2, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29763758/probe-of-zrtio-2-thin-films-with-tio-2-zro-2-binary-oxides-deposited-by-dip-coating-technique
#17
Zohra N Kayani, Anum Kamran, Zeb Saddiqe, Saira Riaz, Shahzad Naseem
Zirconium Titanium dioxide (TiO2 : Zr) thin films were synthesized on glass substrates by the dip coating technique. The structural, optical, magnetic, photo-catalytic and antibacterial properties were explored for the films synthesized with zirconium concentration 10, 15, 20, 25 and 30 at.%. X-ray diffraction (XRD) revealed that the thin films contain anatase-rutile-brookite TiO2 and cubic-ZrO2 phases. Moreover, it was noticed that ZrO2 retarded the anatase-to-rutile transformation at high Zr doping percentage...
May 1, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29747146/verteporfin-mediated-sequence-dependent-combination-therapy-against-ovarian-cancer-cell-line
#18
S Sibel Erdem, Vildan Akgul Obeidin, Turkan Yigitbasi, S Serranur Tumer, Pakize Yigit
Ovarian Cancer is one of the deadliest gynecological cancer showing high resistance to chemotherapy. Non-overlapping and synergistic combination therapies are the best option to overcome this multi-pathological silent disease. Cationic peptides (CPs) with high targeting feature and ability to pass through cell membrane induce apoptosis via disruption of cancer cell membrane. Photodynamic Therapy (PDT) is a noninvasive clinically approved treatment modality combining light activated photosensitizer, light and oxygen...
May 1, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29734113/biogenic-synthesis-characterization-of-gold-and-silver-nanoparticles-from-coleus-forskohlii-and-their-clinical-importance
#19
Manikandan Dhayalan, Michael Immanuel Jesse Denison, Manikandan Ayyar, N N Gandhi, Kathiravan Krishnan, Baykal Abdulhadi
In modern era, the great interest and demand among chemists and researchers for metal nanoparticles is increasing in the application of biomedical fields, textiles, cosmetics and various sectors. Consequently, the present study reports an eco-friendly, cost-effective, rapid and easy method to produce environment-friendly metal nanoparticles to prevent exhaustion of metal resources. In this context, gold and silver metal nanoparticles were green synthesized using the Root Extract of Coleous forskohlii (RECo) as capping and reducing agent...
May 1, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29758545/protection-against-uv-induced-oxidative-stress-and-dna-damage-by-amazon-moss-extracts
#20
A S Fernandes, J L Mazzei, H Evangelista, M R C Marques, E R A Ferraz, I Felzenszwalb
Amazon mosses, such as Holomitriopsis laevifolia and Leucobryum sp. are naturally exposed to high levels of solar ultraviolet (UV) radiation. Theoretically, under environmental stress conditions these mosses have developed protective chemical and metabolic strategies against UV damage, by way of biosynthesis of secondary metabolites, such as flavonoids. The present paper aimed to evaluate the free-radical scavenging activity, and the photoprotective, mutagenic and photomutagenic potencies of the methanolic (ME), aqueous (AE), hydroalcoholic (HE), ethanolic (EE) extracts of H...
April 27, 2018: Journal of Photochemistry and Photobiology. B, Biology
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