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Journal of Cardiology

Hiroki Oe, Nobuhisa Watanabe, Toru Miyoshi, Kazuhiro Osawa, Teiji Akagi, Susumu Kanazawa, Hiroshi Ito
BACKGROUND: Management of adult congenital heart disease (ACHD) patients requires understanding of its complex morphology and functional features. An innovative imaging technique has been developed to display a virtual multi-planar reconstruction obtained from contrast-enhanced multidetector-computed tomography (MDCT) corresponding to the same cross-sectional image from transthoracic echocardiography (TTE). The aim of this study is to assess the usefulness of this imaging technology in ACHD patients...
June 18, 2018: Journal of Cardiology
Junji Moriya
There is accumulating evidence that vascular inflammation plays critical roles in pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive immune responses are important for initiation and progression of atherosclerosis, which mainly consist of monocytes, macrophages, neutrophils, T lymphocytes, and B lymphocytes. Moreover, inflammatory biomarkers such as high-sensitivity C-reactive protein and interleukin-6 are known to predict future cardiovascular events, as well as conventional low-density or high-density lipoprotein cholesterol...
June 12, 2018: Journal of Cardiology
Daisuke Kitano, Tadateru Takayama, Mitsumasa Sudo, Takaaki Kogo, Keisuke Kojima, Naotaka Akutsu, Toshihiko Nishida, Hironori Haruta, Daisuke Fukamachi, Taro Kawano, Takashi Kanai, Takafumi Hiro, Satoshi Saito, Atsushi Hirayma
BACKGROUND: Coronary artery vasospasm (CS) can be identified as either a diffuse type or focal type; however, the difference in endothelial characteristics between these spasm types remains unclear. The features of coronary intima associated with diffuse spasm and focal spasm using coronary angioscopy (CAS) were evaluated and the optical coherence tomography (OCT) findings were compared. METHODS: CAS and/or OCT observational analysis was performed in 55 patients (mean age: 61...
June 10, 2018: Journal of Cardiology
Satoshi Akagi, Hiromi Matsubara, Kazufumi Nakamura, Hiroshi Ito
Treatment goals in pulmonary arterial hypertension (PAH) include improved quality of life and exercise capacity as well as improved life prognosis. In our experience, only remarkable reductions in pulmonary arterial pressure (PAP) improve long-term survival. Lowering PAP could contribute to reverse remodeling by reducing hemodynamic stress. Proper and prompt use of PAH-specific drugs lowers PAP in patients with PAH. Upfront combination therapy with different PAH-specific drugs and quickly establishing high-dose epoprostenol lowers PAP sufficiently to improve prognosis in patients with PAH...
June 10, 2018: Journal of Cardiology
Masaya Shinohara, Tadashi Fujino, Shinntaro Yao, Kensuke Yano, Katsuya Akitsu, Hideki Koike, Toshio Kinoshita, Hitomi Yuzawa, Takeya Suzuki, Kenzaburo Kobayashi, Takanori Ikeda
BACKGROUND: Physicians estimate the frailty in elderly patients with atrial fibrillation (AF) to aid in the decision making with respect to oral anticoagulant (OAC) therapy. There are limited data on the safety of OAC therapy in non-severe frail elderly patients. We evaluated the risk factors of bleeding among non-severe frail octogenarians with AF taking OACs. METHODS: Among 430 consecutive AF patients aged 80 years and over with non-severe frailty, we enrolled 346 patients [167 men, 83...
June 10, 2018: Journal of Cardiology
Giuseppe Lippi, Gianfranco Cervellin
No abstract text is available yet for this article.
June 9, 2018: Journal of Cardiology
Ryota Kosaki, Yoshino Minoura, Kunihiro Ogura, Yosuke Oishi, Lisa Tanaka, Ken Arai, Kosuke Nomura, Koshiro Sakai, Teruo Sekimoto, Tenjin Nisikura, Hiroaki Tsujita, Seita Kondo, Shigeto Tsukamoto, Yuji Hamazaki, Youichi Kobayashi
BACKGROUND: Plasma levels of atherothrombosis-related markers such as endothelial biomarkers have been reported to predict the risk of first acute coronary syndrome (ACS) events. Percutaneous coronary intervention (PCI) by balloon angioplasty and stenting established as a treatment for ACS enabled early discharge and early clinic care. The procedure of PCI, however, may itself be associated with arterial injury with endothelial dysfunction. The clinical significance of those biomarkers for second events in patients after PCI has not yet been completely understood to identify patients who need strict follow-up...
June 7, 2018: Journal of Cardiology
Shuhei Tsuji, Satoshi Koyama, Ryoji Taniguchi, Takako Fujiwara, Hisayoshi Fujiwara, Yukihito Sato
BACKGROUND: Loss of skeletal muscle mass and low nutritional status are major complications of severe chronic heart failure (CHF) and have been associated with poor prognosis. This study aimed to identify the nutritional status of outpatients with CHF based on their body composition, such as skeletal muscle index (SMI) and serum amino acid concentration. METHODS: We compared the body composition data and results of blood samples, including the serum amino acid concentration, of patients with CHF and those of controls...
June 6, 2018: Journal of Cardiology
Tomoyuki Fujita, Satsuki Fukushima, Naonori Kawamoto, Junjiro Kobayashi
No abstract text is available yet for this article.
June 1, 2018: Journal of Cardiology
Anton Tomšič, Yasmine L Hiemstra, Fabienne M A van Hout, Thomas J van Brakel, Michel I M Versteegh, Nina Ajmone Marsan, Robert J M Klautz, Meindert Palmen
BACKGROUND: In asymptomatic patients with severe degenerative mitral valve regurgitation (MR), early surgery is often performed in experienced centers. The patient- and valve-related results and the quality of life after surgery in these patients remain insufficiently explored. METHODS: Between 1/2000 and 12/2015, 83 asymptomatic patients (mean age 56.6±12.6 years, 21 female) without any complications related to long-lasting MR underwent early surgery. Follow-up clinical and echocardiographic data and health-related quality of life assessment (SF-36) were studied and matched to the general population...
May 31, 2018: Journal of Cardiology
Hitoshi Mori, Ritsushi Kato, Yoshifumi Ikeda, Koji Goto, Sayaka Tanaka, So Asano, Yuichiro Shiki, Takahiko Nagase, Mai Tahara, Shiro Iwanaga, Toshihiro Muramatsu, Kazuo Matsumoto
BACKGROUND: Detailed substrate mapping is important for catheter ablation. However, the influence of the electrode spacing of the mapping catheter on the substrate map has not been well clarified. The aim of this study was to investigate the influence of the electrode spacing of the mapping catheter on the voltage of the substrate map. METHODS: Protocol 1: We recorded the local atrial potentials of the left atrium (LA) using the ablation catheter during sinus rhythm in six atrial fibrillation (AF) patients...
May 30, 2018: Journal of Cardiology
Hiroaki Yokoyama, Hirofumi Tomita
No abstract text is available yet for this article.
May 29, 2018: Journal of Cardiology
Giuseppe D Sanna, Eleonora Gabrielli, Elena De Vito, Giuseppe Nusdeo, Domenico Prisco, Guido Parodi
It has been documented that physical activity may increase the risk of atrial fibrillation (AF) in active or former competitive athletes. Different mechanisms are involved and responsible for the development of the arrhythmia, such as structural changes of the left atrium, influences of autonomic nervous system with enhanced vagal tone, and the use of prohibited substances with arrhythmogenic effects. Difficulties in the management of AF in athletes may derive from the low compliance to antiarrhythmic therapy and the selection of the most appropriate strategy for thromboembolic risk prevention...
May 28, 2018: Journal of Cardiology
Katsuhiko Imai
No abstract text is available yet for this article.
May 25, 2018: Journal of Cardiology
Takanori Yamaguchi, Takeshi Tsuchiya, Akira Fukui, Yuki Kawano, Toyokazu Otsubo, Yuya Takahashi, Kei Hirota, Kenta Murotani, Kenichi Eshima, Naohiko Takahashi
BACKGROUND: Low-voltage zones (LVZs), as measured by electroanatomic mapping, are thought to be associated with fibrosis. We reported the efficacy of atrial fibrillation (AF) ablation aiming to homogenize left atrial (LA) LVZ. The purpose of this study was to evaluate the impact of LVZ extension outcomes after LVZ homogenization in patients with nonparoxysmal AF. METHODS: This prospective observational cohort study included 172 patients with nonparoxysmal AF undergoing their initial ablation...
May 25, 2018: Journal of Cardiology
Toshiaki Sakai, Osamu Nishiyama, Masayuki Onodera, Shigekatsu Matsuda, Shinobu Wakisawa, Motoyuki Nakamura, Yoshihiro Morino, Tomonori Itoh
BACKGROUND: The purposes of this study were to create a new flow-chart of prehospital electrocardiography (ECG)-transmission, evaluate its predictive ability for ST-elevation myocardial infarction (STEMI) and shorten door-to-balloon time (DTBT). METHOD AND RESULTS: The new transmission flow-chart was created using symptoms from previous medical records of STEMI patients. A total of 4090 consecutive patients transferred emergently to our hospital were divided into two groups: those in ambulances with an ECG-transmission device with the new flow-chart (ECGT-FC) and those transferred without an ECG-transmission device (non-ECGT) groups...
May 24, 2018: Journal of Cardiology
Ian Jun Yan Wee, Nicholas Syn, Andrew M T L Choong
The caval-aortic path is a novel access route for endovascular aortic interventions in aortic interventions, particularly for patients unsuitable for traditional access routes including femoral, subclavian, transapical, and aortic. A systematic review was conducted as per the PRISMA guidelines utilizing three electronic databases: Medline, Embase, and Cochrane database. There were 10 studies identified, including 7 retrospective studies, 1 prospective cohort study, and 2 case reports. Data on 209 patients (mean age 79...
May 24, 2018: Journal of Cardiology
Masa-Aki Kawashiri, Hayato Tada, Akihiro Nomura, Masakazu Yamagishi
Cardiovascular diseases and their risk factors are inheritable. Single nucleotide polymorphisms in the human genome are found in around 1 in 1000 base pairs, and this may affect the genetic variety of individuals. During meiosis, any genetic information is randomized and is independent of other characteristics. In a Mendelian randomization study (MRS), a genetic variant associated with biomarker is used as a proxy for the biomarker, and the outcomes are compared between the groups harboring the effect alleles and a group with the reference allele...
May 22, 2018: Journal of Cardiology
Seung Hun Lee, Myung Ho Jeong, Ju Han Kim, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Shung Chull Chae, In Whan Seong, Jong Sun Park, Jei Keon Chae, Seung Ho Hur, Kwang-Soo Cha, Hyo-Soo Kim, Hyeon Cheol Gwon, Ki Bae Seung, Seung Woon Rha
BACKGROUND: Ventricular tachycardia or fibrillation (VT/VF) is a major cause of sudden cardiac death after acute myocardial infarction (AMI). This study aims to investigate the clinical characteristics and outcomes of VT/VF, to identify the variables associated with VT/VF, and to construct a new scoring system. METHODS: Patients with relatively preserved left ventricular ejection fraction (LVEF) (≥40%) included in the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were enrolled in this study...
May 17, 2018: Journal of Cardiology
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