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Neurophysiologie Clinique, Clinical Neurophysiology

Laure Peter-Derex, Hélène Catenoix, Hélène Bastuji, Florian Chouchou
OBJECTIVE: Differential diagnosis between sleep-related epileptic seizures and NREM parasomnia remains challenging. Pathophysiological markers to differentiate both conditions are needed. Activation of autonomic system is present in arousal reactions and epileptic seizures. Our study investigated whether cardiac reactivity differed between arousal disorders and sleep-related seizures. METHODS: Nocturnal recordings of 50 patients (10 in each group: frontal lobe epilepsy [FLE], temporal lobe epilepsy [TLE], nocturnal terror [NT], confusional arousal [CA], normal arousals [NA]) were retrospectively selected...
September 15, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Frederic Viseux, Franck Barbier, Philippe Villeneuve, Antoine Lemaire, Pascal Charpentier, Sebastien Leteneur
The purpose of the study was to evaluate the effect of an additional thickness placed under the toes (TUT) on the CoP measures and to determine the optimum thickness required to maximize the postural control performance. Four conditions were compared: TUT 0 (control), 0.8, 3, and 6mm and four variables were computed from the CoP displacements. These results suggest that the lowest TUT could contribute to changing balance control, and may have clinical interest. This brings perspectives in the management of patients with risk of falling or with chronic pain syndromes, complementing validated therapeutic strategies...
September 5, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Prashanth R J Vas, Kalliopi Pafili, Nikolaos Papanas
No abstract text is available yet for this article.
September 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Vasilios K Kimiskidis, Sotirios Papayiannopoulos, Kyriaki Sotirakoglou, Haralambos Karakasis, Zoe Katsarou, Dimitrios A Kazis, Vasileios Papaliagkas, Stylianos Gatzonis, Alexandros Papadimitriou, Georgios Hadjigeorgiou, Sevasti Bostanjopoulou
Mutations in the α-synuclein gene are a rare cause of Parkinson's disease. We investigated, by single-pulse TMS, the cortical excitability profile of nine α-synuclein patients in comparison with 24 idiopathic PD patients, subdivided into "akinetic" (n=17) and "tremor-dominant" (n=7) subgroups. The comparative assessment of rest motor threshold, active MEP and Silent Period Input/Output curves indicated that the cortical excitability of α-Synuclein patients is similar to patients with the "akinetic" form of PD...
September 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Farhad Gholami, Saeed Nikookheslat, Yaghoub Salekzamani, Normand Boule, Afshar Jafari
OBJECTIVE: Peripheral neuropathy (PN) is one of the long-term complications of diabetes. Few studies have investigated the role of regular exercise on diabetic PN. We examined the effect of aerobic training on nerve conduction velocity and action potential amplitude in the lower limbs of men with type 2 diabetes and PN. METHODS: In a randomized controlled study, 24 volunteers diagnosed with diabetic PN were randomly assigned to exercise or control groups. Aerobic training consisted of 20-45min walking or running at 50-70% of heart rate reserve for three sessions per week over 12weeks...
September 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Clémence Lopez, Cherhazad Hemimou, Bernard Golse, Laurence Vaivre-Douret
OBJECTIVES: Children with developmental coordination disorder (DCD) are particularly affected by handwriting disorders, which remain poorly understood and are not clearly defined. The aim of our study is to provide a better understanding of handwriting disorders, and specifically of dysgraphia in children with DCD. METHODS: Sixty-five children with DCD (5-15 years), enrolled according to DSM-5, were assessed with handwriting testing and standardized assessments of neuropsychological, neurovisual, MRI and neuropsychomotor functions, with special attention paid to muscular tone examination...
September 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Valquíria Aparecida da Silva, Ricardo Galhardoni, Manoel Jacobsen Teixeira, Daniel Ciampi de Andrade
INTRODUCTION: Heterotopic conditioned pain modulation (CPM) has provided potentially useful clinical information such as response to medication in neuropathic pain or the prediction of pain after surgical procedures. Despite these advances, several methodological aspects of CPM remain to be determined, such as the impact of the conditioning stimulus (CS) type upon CPM, if its evoked-pain intensity is controlled for [measured on a visual analogue scale (VAS: 0-100mm)]. OBJECTIVES: To explore potential differential effects of CPM using three distinct CS (having similar evoked-pain intensity) in the same individuals...
June 25, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Simon Podnar, Leja Dolenc Grošelj
OBJECTIVE: Both myopathic and neuropathic tongue protruder muscle changes have been demonstrated to occur in obstructive sleep apnea (OSA) patients using different methods. We tried to elucidate this dilemma using quantitative electromyographic (EMG) methods. METHODS: In a group of consecutive patients with suspected OSA a full overnight polysomnography (PSG) and quantitative needle EMG of the tongue protruder, biceps brachii and vastus lateralis muscles were performed...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Hasan Hodaj, Jean-François Payen, Jean-Pascal Lefaucheur
OBJECTIVE: To show that repetitive transcranial magnetic stimulation (rTMS) delivered at high frequency over the motor cortex can improve patients with chronic pain syndrome even if this procedure does not provide an analgesic response. CASE REPORT: A 77-year-old woman presented with drug-resistant chronic neuropathic pain affecting both lower limbs due to segmental spine compression at T9-T10 level. She underwent an rTMS protocol with an induction phase of 12 rTMS sessions during three weeks and a maintenance phase of 3 additional rTMS sessions for 5 weeks...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Jean-Paul Nguyen, Sylvie Raoul, Hubert Desal, Romain Bourcier, Emmanuelle Kuhn, Véronique Dixneuf, Philippe Damier, Jean-Pascal Lefaucheur, Julien Nizard
This pilot study aimed at assessing the effect of transcutaneous electrical nerve stimulation (TENS) of the occipital nerve (ON) to treat chronic refractory headache secondary to intracranial endovascular procedures (iEVP) in 4 patients. The duration of ON-TENS therapy was only 1 month (n=2) or longer than 4 months (n=2). Overall, pain intensity decreased from 7.8 (on a 0-10 scale) at baseline to 0.8 at 6 months after ON-TENS therapy initiation (-90%), while drug treatment was reduced from 34.3 to 0.8 (-98%) on the medication quantification scale...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Nathalie André-Obadia, Julie Zyss, Martine Gavaret, Jean-Pascal Lefaucheur, Eric Azabou, Sébastien Boulogne, Jean-Michel Guérit, Aileen McGonigal, Philippe Merle, Véronique Mutschler, Lionel Naccache, Cécile Sabourdy, Agnès Trébuchon, Louise Tyvaert, Laurent Vercueil, Benjamin Rohaut, Arnaud Delval
Predicting the outcome of a comatose or poorly responsive patient is a major issue for intensive care unit teams, in order to give the most accurate information to the family and to choose the best therapeutic option. However, determining the level of cortical activity in patients with disorders of consciousness is a real challenge. Reliable criteria are required to help clinicians in the decision-making process, especially in the acute phase of coma. In this paper, we propose recommendations for recording and interpreting electroencephalography and evoked potentials in comatose patients based on the literature and the clinical experience of a group of neurophysiologists trained in the management of comatose patients...
June 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Jonathan Monin, Estelle Pruvost-Robieux, Nicolas Huiban, Angela Marchi, Benoit Crepon, Dominique Dubourdieu, Eric Perrier, Martine Gavaret
INTRODUCTION: In France, a systematic EEG is performed during initial examination in military aircrew applicants, which may provide an estimation of the prevalence of benign epileptiform variants in healthy adults. METHODS: We analyzed standard EEG (21 scalp electrodes, 20minutes, 400Hz sampling rate) of military aircrew applicants examined in the French Main Aeromedical Center in 2016. EEGs were analyzed using both bipolar and referential montages. The collected data were EEG abnormalities and benign epileptiform variants...
June 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Meral E Kızıltan, Oya Öztürk, Ayşegül Gündüz
OBJECTIVE: Threatening stimuli encountered in peripersonal space (PPS) are processed differently from those encountered in extrapersonal space (EPS). This phenomenon is attributed to tonic top-down modulation. We hypothesized that prepulse inhibition (PPI) of a reflex, which has a protective function, may change according to whether the conditioning stimulus appears in PPS or EPS. We aimed to compare the strength of the PPI according to whether stimulation was delivered in PPS or EPS...
June 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Meral E Kızıltan, Ayşegül Gündüz
No abstract text is available yet for this article.
June 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Martine Gavaret, Samar S Ayache, Veit Mylius, Alaa Mhalla, Moussa A Chalah, Jean-Pascal Lefaucheur
OBJECTIVES: Paired associative stimulation (PAS) can modulate motor excitability and consists of delivering repeated pairs of peripheral sensory stimulation combined with transcranial magnetic stimulation (TMS) over the contralateral motor cortex. Our objective was to evaluate the effect of a PAS protocol using a painful stimulation. METHODS: Ten healthy volunteers underwent pain-PAS protocol consisting of 90 pairs of nociceptive stimulus over the right hand followed by an image-guided navigated TMS of the contralateral motor cortex, delivered at 0...
May 9, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Daniele Coraci, Silvia Giovannini, Claudia Loreti, Luca Padua
No abstract text is available yet for this article.
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Eman M Khedr, Noha Abo El-Fetoh, Dina H El-Hammady, Abeer M Ghandour, Khaled Osama, Ahmed F Zaki, Ayman Gamea
OBJECTIVE: Recovery from acute Bell's palsy (BP) is variable and there are few predictors of response. We evaluated the usefulness of a range of neurophysiological parameters to predict outcome in BP. METHODS: Fifty-nine patients (age: 33.7±15.4 years) with acute unilateral BP were recruited within 3-7 days of onset. They were evaluated with electroneurography, facial nerve excitability, and the blink reflex. House-Brackmann (HB) clinical scores were obtained at the same time and three months later...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Philippe Vignaud, Marine Mondino, Emmanuel Poulet, Ulrich Palm, Jérôme Brunelin
Recent studies have shown heterogeneous results regarding the influence of intensity and duration of motor transcranial direct current stimulation (tDCS) on cortical excitability. In this pilot crossover study including 14 healthy participants, we compared the effects of a single session of anodal-tDCS set with two commonly used durations (20 and 30minutes) and intensities (1 and 2mA) on short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF). Regardless of the current intensity, 20minutes of tDCS increased SICI (3ms inter-stimulus interval ISI) and decreased ICF (7ms ISI); 30minutes of tDCS did not affect cortical excitability...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Simon Podnar
OBJECTIVE: Although ultrasonographic (US) visualization of peripheral nerves is becoming more and more frequently used, there are few studies on its actual contribution to the diagnosis and management of patients with peripheral nerve disorders. METHODS: The electronic records of consecutive patients referred to our US laboratory over an eight-month period were retrospectively analyzed. The contribution of US examination to patient management was evaluated. RESULTS: Two hundred and thirty one consecutive patients (43% men) were analyzed...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Laura Säisänen, Petro Julkunen, Timo Lakka, Virpi Lindi, Mervi Könönen, Sara Määttä
OBJECTIVES: We characterized the maturation of the excitability of the motor cortex and corticospinal tract from childhood to adulthood using electric field (EF) navigated TMS and correlated the results with manual dexterity. METHODS: Both hemispheres of healthy right-handed children (6-9 years, n=10), preadolescents (10-12 years, n=13), adolescents (14-17 years, n=12) and young adults (22-34 years, n=12) of both genders were examined. The optimal cortical representation site and resting motor threshold (rMT) were determined for the abductor pollicis brevis muscle...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
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