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Neurophysiologie Clinique, Clinical Neurophysiology

Valquíria Aparecida da Silva, Ricardo Galhardoni, Manoel Jacobsen Teixeira, Daniel Ciampi de Andrade
INTRODUCTION: Heterotopic conditioned pain modulation (CPM) has provided potentially useful clinical information such as response to medication in neuropathic pain or the prediction of pain after surgical procedures. Despite these advances, several methodological aspects of CPM remain to be determined, such as the impact of the conditioning stimulus (CS) type upon CPM, if its evoked-pain intensity is controlled for [measured on a visual analogue scale (VAS: 0-100mm)]. OBJECTIVES: To explore potential differential effects of CPM using three distinct CS (having similar evoked-pain intensity) in the same individuals...
June 25, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Simon Podnar, Leja Dolenc Grošelj
OBJECTIVE: Both myopathic and neuropathic tongue protruder muscle changes have been demonstrated to occur in obstructive sleep apnea (OSA) patients using different methods. We tried to elucidate this dilemma using quantitative electromyographic (EMG) methods. METHODS: In a group of consecutive patients with suspected OSA a full overnight polysomnography (PSG) and quantitative needle EMG of the tongue protruder, biceps brachii and vastus lateralis muscles were performed...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Hasan Hodaj, Jean-François Payen, Jean-Pascal Lefaucheur
OBJECTIVE: To show that repetitive transcranial magnetic stimulation (rTMS) delivered at high frequency over the motor cortex can improve patients with chronic pain syndrome even if this procedure does not provide an analgesic response. CASE REPORT: A 77-year-old woman presented with drug-resistant chronic neuropathic pain affecting both lower limbs due to segmental spine compression at T9-T10 level. She underwent an rTMS protocol with an induction phase of 12 rTMS sessions during three weeks and a maintenance phase of 3 additional rTMS sessions for 5 weeks...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Jean-Paul Nguyen, Sylvie Raoul, Hubert Desal, Romain Bourcier, Emmanuelle Kuhn, Véronique Dixneuf, Philippe Damier, Jean-Pascal Lefaucheur, Julien Nizard
This pilot study aimed at assessing the effect of transcutaneous electrical nerve stimulation (TENS) of the occipital nerve (ON) to treat chronic refractory headache secondary to intracranial endovascular procedures (iEVP) in 4 patients. The duration of ON-TENS therapy was only 1 month (n=2) or longer than 4 months (n=2). Overall, pain intensity decreased from 7.8 (on a 0-10 scale) at baseline to 0.8 at 6 months after ON-TENS therapy initiation (-90%), while drug treatment was reduced from 34.3 to 0.8 (-98%) on the medication quantification scale...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Prashanth R J Vas, Kalliopi Pafili, Nikolaos Papanas
No abstract text is available yet for this article.
May 10, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Martine Gavaret, Samar S Ayache, Veit Mylius, Alaa Mhalla, Moussa A Chalah, Jean-Pascal Lefaucheur
OBJECTIVES: Paired associative stimulation (PAS) can modulate motor excitability and consists of delivering repeated pairs of peripheral sensory stimulation combined with transcranial magnetic stimulation (TMS) over the contralateral motor cortex. Our objective was to evaluate the effect of a PAS protocol using a painful stimulation. METHODS: Ten healthy volunteers underwent pain-PAS protocol consisting of 90 pairs of nociceptive stimulus over the right hand followed by an image-guided navigated TMS of the contralateral motor cortex, delivered at 0...
May 9, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Vasilios K Kimiskidis, Sotirios Papayiannopoulos, Kyriaki Sotirakoglou, Haralambos Karakasis, Zoe Katsarou, Dimitrios A Kazis, Vasileios Papaliagkas, Stylianos Gatzonis, Alexandros Papadimitriou, Georgios Hadjigeorgiou, Sevasti Bostanjopoulou
Mutations in the α-synuclein gene are a rare cause of Parkinson's disease. We investigated, by single-pulse TMS, the cortical excitability profile of nine α-synuclein patients in comparison with 24 idiopathic PD patients, subdivided into "akinetic" (n=17) and "tremor-dominant" (n=7) subgroups. The comparative assessment of rest motor threshold, active MEP and Silent Period Input/Output curves indicated that the cortical excitability of α-Synuclein patients is similar to patients with the "akinetic" form of PD...
May 2, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Nathalie André-Obadia, Julie Zyss, Martine Gavaret, Jean-Pascal Lefaucheur, Eric Azabou, Sébastien Boulogne, Jean-Michel Guérit, Aileen McGonigal, Philippe Merle, Véronique Mutschler, Lionel Naccache, Cécile Sabourdy, Agnès Trébuchon, Louise Tyvaert, Laurent Vercueil, Benjamin Rohaut, Arnaud Delval
Predicting the outcome of a comatose or poorly responsive patient is a major issue for intensive care unit teams, in order to give the most accurate information to the family and to choose the best therapeutic option. However, determining the level of cortical activity in patients with disorders of consciousness is a real challenge. Reliable criteria are required to help clinicians in the decision-making process, especially in the acute phase of coma. In this paper, we propose recommendations for recording and interpreting electroencephalography and evoked potentials in comatose patients based on the literature and the clinical experience of a group of neurophysiologists trained in the management of comatose patients...
June 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Jonathan Monin, Estelle Pruvost-Robieux, Nicolas Huiban, Angela Marchi, Benoit Crepon, Dominique Dubourdieu, Eric Perrier, Martine Gavaret
INTRODUCTION: In France, a systematic EEG is performed during initial examination in military aircrew applicants, which may provide an estimation of the prevalence of benign epileptiform variants in healthy adults. METHODS: We analyzed standard EEG (21 scalp electrodes, 20minutes, 400Hz sampling rate) of military aircrew applicants examined in the French Main Aeromedical Center in 2016. EEGs were analyzed using both bipolar and referential montages. The collected data were EEG abnormalities and benign epileptiform variants...
June 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Meral E Kızıltan, Oya Öztürk, Ayşegül Gündüz
OBJECTIVE: Threatening stimuli encountered in peripersonal space (PPS) are processed differently from those encountered in extrapersonal space (EPS). This phenomenon is attributed to tonic top-down modulation. We hypothesized that prepulse inhibition (PPI) of a reflex, which has a protective function, may change according to whether the conditioning stimulus appears in PPS or EPS. We aimed to compare the strength of the PPI according to whether stimulation was delivered in PPS or EPS...
April 6, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Daniele Coraci, Silvia Giovannini, Claudia Loreti, Luca Padua
No abstract text is available yet for this article.
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Eman M Khedr, Noha Abo El-Fetoh, Dina H El-Hammady, Abeer M Ghandour, Khaled Osama, Ahmed F Zaki, Ayman Gamea
OBJECTIVE: Recovery from acute Bell's palsy (BP) is variable and there are few predictors of response. We evaluated the usefulness of a range of neurophysiological parameters to predict outcome in BP. METHODS: Fifty-nine patients (age: 33.7±15.4 years) with acute unilateral BP were recruited within 3-7 days of onset. They were evaluated with electroneurography, facial nerve excitability, and the blink reflex. House-Brackmann (HB) clinical scores were obtained at the same time and three months later...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Philippe Vignaud, Marine Mondino, Emmanuel Poulet, Ulrich Palm, Jérôme Brunelin
Recent studies have shown heterogeneous results regarding the influence of intensity and duration of motor transcranial direct current stimulation (tDCS) on cortical excitability. In this pilot crossover study including 14 healthy participants, we compared the effects of a single session of anodal-tDCS set with two commonly used durations (20 and 30minutes) and intensities (1 and 2mA) on short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF). Regardless of the current intensity, 20minutes of tDCS increased SICI (3ms inter-stimulus interval ISI) and decreased ICF (7ms ISI); 30minutes of tDCS did not affect cortical excitability...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Simon Podnar
OBJECTIVE: Although ultrasonographic (US) visualization of peripheral nerves is becoming more and more frequently used, there are few studies on its actual contribution to the diagnosis and management of patients with peripheral nerve disorders. METHODS: The electronic records of consecutive patients referred to our US laboratory over an eight-month period were retrospectively analyzed. The contribution of US examination to patient management was evaluated. RESULTS: Two hundred and thirty one consecutive patients (43% men) were analyzed...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Laura Säisänen, Petro Julkunen, Timo Lakka, Virpi Lindi, Mervi Könönen, Sara Määttä
OBJECTIVES: We characterized the maturation of the excitability of the motor cortex and corticospinal tract from childhood to adulthood using electric field (EF) navigated TMS and correlated the results with manual dexterity. METHODS: Both hemispheres of healthy right-handed children (6-9 years, n=10), preadolescents (10-12 years, n=13), adolescents (14-17 years, n=12) and young adults (22-34 years, n=12) of both genders were examined. The optimal cortical representation site and resting motor threshold (rMT) were determined for the abductor pollicis brevis muscle...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Anne Pavy-LeTraon, Christine Brefel-Courbon, Julia Dupouy, Fabienne Ory-Magne, Olivier Rascol, Jean-Michel Senard
OBJECTIVES: It can be difficult to differentiate multiple system atrophy (MSA) with predominant parkinsonism (MSA-P), a very disabling but rare disease, from Parkinson's disease (PD). Autonomic dysfunction, particularly cardiovascular autonomic neuropathy (CAN), is classically more pronounced in MSA. We investigated whether testing for CAN combined with sweat function assessment was helpful to differentiate patients with MSA from those with PD. METHODS: In this retrospective study, 62 patients with MSA-P and 96 with PD, comparable in age, BMI and sex ratio with disease duration of 4...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Pedro Calderón, Paul Deltenre, Ida Stany, Jean-Paul Kaleeta Maalu, Magali Stevens, Jean Lamoureux, Michel Bellemans, Sylvie Dujardin, Philippe Van der Linden, Bernard Dachy
OBJECTIVE: To study the effect of clonidine administrated as a co-analgesic during scoliosis surgery, on the neuromonitoring of spinal motor pathways. METHODS: Using standardized intraoperative monitoring, we compared the time course of peripherally and transcranially electrically evoked motor potentials (TcEMEPs) before and after injection of a single bolus of clonidine in children under total intravenous anesthesia (TIVA). MEP data were obtained from 9 patients and somatosensory evoked potentials (SSEPs) were obtained from 2 patients...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Filippo Zappasodi, Gabriella Musumeci, Riccardo Navarra, Vincenzo Di Lazzaro, Massimo Caulo, Antonino Uncini
OBJECTIVE: To assess the safety and effects on motor cortex excitability of five cathodal-tDCS sessions (charge density 342.9C/m2 ) delivered over the dominant motor cortex with a return electrode over the ipsilateral shoulder at increasing time intervals in 25hours. METHODS: Safety was operatively defined as absence of serious adverse events related to tDCS including brain tissue alterations documentable by magnetic resonance imaging and spectroscopy. Effects on motor cortex excitability were evaluated by motor evoked potential (MEP) amplitude...
April 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Paul Fourcade, Simon Bouisset, Serge Le Bozec, Sahel Memari
AIM: This paper examines the postural adjustments that occur after the end of a voluntary movement (consecutive postural adjustments, CPAs). Its aim is to reinforce the theory that CPAs are necessary to counterbalance the destabilizing effect of a voluntary movement. In addition, we compared the main features of CPAs with those of anticipatory postural adjustments (APAs) in order to gather evidence that could afford new insights into postural programming. METHODS: Nine healthy adults were invited to adopt a sitting position to perform nine pointing movements at decreasing velocities...
March 29, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Farhad Gholami, Saeed Nikookheslat, Yaghoub Salekzamani, Normand Boule, Afshar Jafari
OBJECTIVE: Peripheral neuropathy (PN) is one of the long-term complications of diabetes. Few studies have investigated the role of regular exercise on diabetic PN. We examined the effect of aerobic training on nerve conduction velocity and action potential amplitude in the lower limbs of men with type 2 diabetes and PN. METHODS: In a randomized controlled study, 24 volunteers diagnosed with diabetic PN were randomly assigned to exercise or control groups. Aerobic training consisted of 20-45min walking or running at 50-70% of heart rate reserve for three sessions per week over 12weeks...
March 29, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
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