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Korean Journal of Ophthalmology: KJO

Jong Young Lee, Eun Kyoung Lee, Hye Jin Lee, Jinho Jeong, Sang Yoon Lee, Jin Young Kim
No abstract text is available yet for this article.
October 2018: Korean Journal of Ophthalmology: KJO
Jinhyun Kim, Seungwoo Lee
No abstract text is available yet for this article.
October 2018: Korean Journal of Ophthalmology: KJO
Seok Jin Hwang, Keun Hae Kim
No abstract text is available yet for this article.
October 2018: Korean Journal of Ophthalmology: KJO
Kai Ching Peter Leung, Philip Ko, Chun Ho Jonathan Ho, Tak Chuen Simon Ko
No abstract text is available yet for this article.
October 2018: Korean Journal of Ophthalmology: KJO
Junsung Lee, Unbyeol Goh, Ji Ho Park, Sang Woo Park, Hwan Heo
PURPOSE: To improve the treatment efficiency of optic nerve diseases by delivering therapeutic materials to the optic nerve directly. METHODS: We tried to optimize liposomal composition to deliver a payload to the optic nerve efficiently when it is injected intravitreally. After loading dexamethasone into this liposome, we tested the therapeutic effect of liposomes in this treatment using a murine model of ischemic optic neuropathy. RESULTS: Our optimized liposome can deliver its payload to the optic nerve more efficiently than other tested compositions...
October 2018: Korean Journal of Ophthalmology: KJO
Jae Hyuck Lee, Jae Yeun Lee, Jeong Hun Bae, Joon Mo Kim
PURPOSE: To compare posture-induced intraocular pressure (IOP) changes in vitrectomized eyes and normal eyes of patients who had vitrectomy in one eye. METHODS: A total of 31 patients older than 20 years of age who underwent vitrectomy were enrolled in the study. At least six months after vitrectomy, we measured IOP in both eyes using a rebound tonometer 10 minutes after the patient assumed sitting, supine, right lateral decubitus, and left lateral decubitus positions...
October 2018: Korean Journal of Ophthalmology: KJO
Jaehyuck Jo, Kyung Rim Sung, Yoon Jeon Kim
PURPOSE: To evaluate the outcome of Ahmed glaucoma valve (AGV) implantation in eyes with refractory secondary glaucoma following pars plana vitrectomy (PPV) and the associated prognostic factors. METHODS: A total of 146 eyes in 146 patients who underwent AGV implantation after PPV (followed up for ≥1 year) were included. AGV implantation was considered successful when the intraocular pressure (IOP) was 6 to 21 mmHg regardless of using IOP-lowering medication. The hazard ratios (HRs) associated with surgical failure were determined with Cox proportional analysis...
October 2018: Korean Journal of Ophthalmology: KJO
Hyun Jin Jeong, Hae Young Lopilly Park, Chan Kee Park
PURPOSE: To evaluate the long-term effects of early postoperative intraocular pressure (IOP) after Ahmed glaucoma valve (AGV) implantation on long-term surgical outcomes. METHODS: This retrospective, non-randomized study included 100 eyes of 100 patients who underwent AGV surgery. We divided the enrolled patients into four groups according to the presence of transient hypotony within the first postoperative week or the presence of a hypertensive phase during the first three postoperative months...
October 2018: Korean Journal of Ophthalmology: KJO
Woo Keun Song, Kyung Rim Sung, Joong Won Shin, Junki Kwon
PURPOSE: To identify the preoperative biometric factors, including subfoveal choroidal thickness (CT), associated with refractive outcome after cataract surgery in eyes with primary angle closure (PAC). METHODS: This study included 50 eyes of 50 PAC patients who underwent uneventful cataract surgery. Preoperatively, anterior segment parameters including anterior chamber depth (ACD) and lens vault were determined by anterior segment optical coherence tomography. Subfoveal CT was measured by spectral domain optical coherence tomography enhanced depth imaging before and at one month after surgery...
October 2018: Korean Journal of Ophthalmology: KJO
Jun Woo Park, Joo Eun Lee, Kang Yeun Pak
PURPOSE: To evaluate posterior vitreous structures using swept-source (SS) optical coherence tomography (OCT) with en face imaging. METHODS: We retrospectively reviewed OCT images of healthy individuals who did not have intra-ocular disease. We obtained high-definition horizontal and vertical line scans crossing the fovea and 3D scans using SS-OCT, with the 3D scan centered between the fovea and the optic-nerve head. An enhanced vitreous visualization function was used to highlight vitreous structures...
October 2018: Korean Journal of Ophthalmology: KJO
Min Ho Shin, Hyun Ji Kang, Seong Jae Kim, In Young Chung, Seong Wook Seo, Ji Myong Yoo, Jong Moon Park, Yong Seop Han
PURPOSE: To compare changes in anterior segment parameters after Nd:YAG laser capsulotomy in eyes that underwent either combined phacovitrectomy or cataract surgery. METHODS: This retrospective study enrolled 37 eyes of 35 patients with posterior capsular opacification treated with combined phacovitrectomy (group A), and 35 eyes of 32 patients with posterior capsular opacification treated with cataract surgery (group B). Anterior segment parameters, including anterior chamber depth (ACD), anterior chamber angle, and anterior chamber volume, were measured by a Pentacam before Nd:YAG laser capsulotomy and 1 hour, 1 day, 1 week, 1 month, and 3 months after this treatment...
October 2018: Korean Journal of Ophthalmology: KJO
Young Suk Chang, Jae Hui Kim, Jong Woo Kim, Chul Gu Kim, Dong Won Lee
PURPOSE: This study aimed to evaluate changes in visual acuity before and after the development of submacular hemorrhage secondary to neovascular age-related macular degeneration (AMD) and to compare the visual outcomes between patients with and without hemorrhage. METHODS: This retrospective observational study included 124 patients with neovascular AMD. Patients who developed a submacular hemorrhage involving the fovea were included in the hemorrhage group (n = 55)...
October 2018: Korean Journal of Ophthalmology: KJO
Gyu Nam Kim, Woong Sun Yoo, Mi Hwa Park, Jin Kwon Chung, Yong Seop Han, In Young Chung, Seong Wook Seo, Ji Myong Yoo, Seong Jae Kim
PURPOSE: To describe the clinical manifestations of herpes simplex keratitis (HSK) in a tertiary referral center in South Korea and to determine whether ascorbic acid treatment prevents recurrence of herpetic epithelial keratitis. METHODS: This retrospective cohort study included all consecutive patients with herpetic keratitis referred to our center from January 2010 to January 2015. Clinical features, ocular complications, and recurrences were recorded. RESULTS: In total, 149 eyes of the 133 patients (72 male and 61 female) were followed for an average of 24...
October 2018: Korean Journal of Ophthalmology: KJO
Sang Min Lee, Sok Joong Chung, Jong Seo Park, Helen Lew
PURPOSE: The lower eyelid serves important roles in tear distribution and drainage. The purpose of this study was to measure the tear meniscus height (TMH) with anterior segment optical coherence tomography after lower blepharoplasty. METHODS: A total of 52 eyes from 26 patients treated between July 2012 and June 2015 were included in the study. A transcutaneous or transconjunctival approach was performed, depending on whether (1) the supportive lower lid orbicularis oculi muscle was tightened, (2) the middle lamella was elongated, (3) minimal fat was removed or transpositioned, and (4) lateral canthal support was established...
October 2018: Korean Journal of Ophthalmology: KJO
Jeong Min Lee, Ji Sun Baek, Hye Sun Choi, Sung Joo Kim, Jae Woo Jang
PURPOSE: To analyze the clinical features of benign essential blepharospasm in Korean patients. METHODS: Patients diagnosed with benign essential blepharospasm in Kim's Eye Hospital from November 2014 to December 2016 were evaluated using a clinical examination and questionnaire. The questionnaire reviewed personal medical history, demographic factors, risk factors for blepharospasm development, and relieving and aggravating factors. RESULTS: Of the 101 patients enrolled, 78 (77...
October 2018: Korean Journal of Ophthalmology: KJO
Jae Byoung Chae, Chang Rae Rho, Jeong Ah Shin, Jungmook Lyu, Seungbum Kang
PURPOSE: Anti-vascular endothelial growth factor (VEGF) agents have been used for the last 10 years, but their safety profile, including cytotoxicity against various ocular cells such as retinal pigment epithelial (RPE) cells, remains a serious concern. Safety studies of VEGF agents conducted to date have primarily relied on healthy RPE cells. In this study, we assessed the safety of three anti-VEGF agents, namely, ranibizumab, bevacizumab, and aflibercept, on senescent RPE cells. METHODS: Senescent human induced pluripotent stem cell-derived RPE cells were generated by continuous replication and confirmed with senescence biomarkers...
August 2018: Korean Journal of Ophthalmology: KJO
Jung Yup Kim, Hae Rang Kim, Soo Jung Lee
PURPOSE: To compare the characteristics of patients with surgically overcorrected intermittent exotropia treated with alternate patching. METHODS: The medical records of 51 patients who underwent bilateral lateral rectus muscle recession for intermittent exotropia and required alternate patching to correct postoperative overcorrection were retrospectively reviewed. Patients with postoperative esodeviation ≥18 prism diopters (PD) were started on alternate patching on postoperative day 1, whereas those with postoperative esodeviation of 10 to 17 PD were started after 2 weeks...
August 2018: Korean Journal of Ophthalmology: KJO
Zhale Rajavi, Hamideh Sabbaghi, Narges Behradfar, Mehdi Yaseri, Mohammad Aghazadeh Amiri, Mohammad Faghihi
PURPOSE: To compare the macular retinal thickness of moderately to severely amblyopic eyes with non-amblyopic eyes as controls. METHODS: This case control study was conducted on 56 children aged 4 to 10 years old (64.3% female subjects). Twenty-eight children had unilateral amblyopia (28 amblyopic eyes as cases and 28 normal fellow eyes as internal controls) and 28 children had normal visual acuity in both eyes and were considered as external controls (n = 56 eyes)...
August 2018: Korean Journal of Ophthalmology: KJO
Heesuk Kim, Hong Kyu Kim, Jong Yun Yang, Sung Soo Kim
PURPOSE: This study investigated visual acuity (VA) values and differences depending on optical coherence tomography (OCT) findings in patients with acute central retinal artery occlusion (CRAO). METHODS: A retrospective chart review was performed on patients with acute CRAO who underwent macular and disc OCT. We evaluated changes in macular thickness and retinal nerve fiber layer (RNFL) thickness after acute CRAO onset based on OCT. We also determined the association of thickness changes with VA improvement...
August 2018: Korean Journal of Ophthalmology: KJO
Mahmut Kaya, Eyyup Karahan, Taylan Ozturk, Nilufer Kocak, Suleyman Kaynak
PURPOSE: To evaluate the effectiveness of intravitreal injection of ranibizumab (IVR) in treating diabetic macular edema (DME) with serous retinal detachment (SRD) based on spectral domain optical coherence tomography (SD-OCT) patterns. METHODS: One hundred thirty-four eyes of 134 patients with DME who underwent SD-OCT evaluation were included in this study. We retrospectively analyzed the medical records of patients who received IVR for the treatment of DME. Their eyes were classified into three groups according to the following SD-OCT features: SRD, diffuse retinal thickness and cystoid macular edema...
August 2018: Korean Journal of Ophthalmology: KJO
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