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European Journal of Clinical Nutrition

Simona Bertoli, Andrea Foppiani, Ramona De Amicis, Alessandro Leone, Chiara Mastella, Michela Bassano, Ester Giaquinto, Giovanni Baranello, Alberto Battezzati
Spinal muscular atrophy (SMA) is a neuromuscular disease associated with nutritional status derangement and altered body composition. New drugs are changing the natural history of the disease, so now more than ever is important to focus on the correct assessment of nutritional status in SMA. We implemented a standardization process for the anthropometric measurement as part of our ongoing longitudinal study of growth patterns in SMA patients. It features a procedural manual, included in this communication, observers training and reliability assessment, of which we publish the values obtained in our pilot study...
January 15, 2019: European Journal of Clinical Nutrition
Sven Knüppel, Matthias Clemens, Johanna Conrad, Sylvia Gastell, Karin B Michels, Michael Leitzmann, Lilian Krist, Tobias Pischon, Gerard Krause, Wolfgang Ahrens, Nina Ebert, Karl-Heinz Jöckel, Alexander Kluttig, Nadia Obi, Rudolf Kaaks, Wolfgang Lieb, Sabine Schipf, Hermann Brenner, Thorsten Heuer, Ulrich Harttig, Jakob Linseisen, Ute Nöthlings, Heiner Boeing
BACKGROUND/OBJECTIVES: The aim of the study was to describe a novel dietary assessment strategy based on two instruments complemented by information from an external population applied to estimate usual food intake in the large-scale multicenter German National Cohort (GNC). As proof of concept, we applied the assessment strategy to data from a pretest study (2012-2013) to assess the feasibility of the novel assessment strategy. SUBJECTS/METHODS: First, the consumption probability for each individual was modeled using three 24 h food lists (24h-FLs) and frequencies from one food frequency questionnaire (FFQ)...
January 15, 2019: European Journal of Clinical Nutrition
Joaquim Calvo-Lerma, Paula Crespo-Escobar, Sandra Martínez-Barona, Victoria Fornés-Ferrer, Ester Donat, Carmen Ribes-Koninckx
BACKGROUND/OBJECTIVES: Gluten-free diet is the lifelong therapy for patients with coeliac disease. A wide range of gluten-free products (GFP) is available, which mimics the characteristics of their gluten-containing counterparts (GCC). The aim of this study was to compare the macronutrient and dietary fibre composition of GFP and GCC currently available in Spain. SUBJECTS/METHODS: A cross-sectional study analysing the nutritional differences between 621 GFP and 600 GCC based on labelling information was conducted...
January 15, 2019: European Journal of Clinical Nutrition
Jie Zeng, Kun Wang, Fayin Ye, Lin Lei, Yun Zhou, Jia Chen, Guohua Zhao, Hui Chang
Epidemiological studies focusing on the association between folate and breast cancer risk reported inconsistent findings. We conducted a systematic search of the literature using PubMed and EMBASE databases. A total of 23 prospective studies involving 41,516 cases and 1,171,048 individuals were included for meta-analysis. Folate intake may decrease the risk of oestrogen receptor (ER) negative (-) and ER-/progesterone receptor (PR)- breast cancer, with pooled risk ratios (RRs) of 0.88 [95% confidence interval (CI): 0...
January 15, 2019: European Journal of Clinical Nutrition
Rajeevalochana Parthasarathy, Elizabeth Oei, Stanley L Fan
BACKGROUND/OBJECTIVES: Bioimpedance analysis is often routinely performed in any dialysis unit to guide fluid management but can provide a reproduceable assessment of fat and muscle mass. We wished to determine the clinical significance of low muscle or high fat mass and the determinants that influence their change. SUBJECTS/METHODS: We performed retrospective analysis of 824 patients on peritoneal dialysis who underwent routine repeated bioimpedance analysis measurements using the body composition monitor (BCM)...
January 15, 2019: European Journal of Clinical Nutrition
Saeed Chashmniam, Seyed Reza Mirhafez, Maryam Dehabeh, Mitra Hariri, Mohsen Azimi Nezhad, B Fatemeh Nobakht M Gh
BACKGROUND/OBJECTIVES: Curcumin, a natural polyphenol compound in the spice turmeric, has been found to have potent anti-oxidative and anti-inflammatory activity. Curcumin may treat non-alcoholic fatty liver disease (NAFLD) through its beneficial effects on biomarkers of oxidative stress (OS) and inflammation, which are considered as two feature of this disease. However, the effects of curcumin on NAFLD have been remained poorly understood. This investigation evaluated the effects of administrating curcumin on metabolic status in NAFLD patients...
January 15, 2019: European Journal of Clinical Nutrition
Dorothy Marie Meyer, Christina Brei, Lynne Stecher, Daniela Much, Stefanie Brunner, Hans Hauner
BACKGROUND/OBJECTIVES: Limited research suggests that exposure to long-chain PUFAs (LCPUFAs) during perinatal development can influence adipose tissue expansion later in life. In previous analyses, we observed that maternal LCPUFAs in late gestation promote offspring gestational growth, whereas breast milk n-3 LCPUFAS promote adipogenesis in infants up to 1 year. This follow-up analysis examines these relationships in offspring up to 5 years. SUBJECTS/METHODS: In this observational study of 169 children, relationships between n-3, n-6 LCPUFAs, and the n-6/n-3 LCPUFA ratio in maternal blood at 32 weeks' gestation, cord blood, and breast milk, and anthropometry in offspring from 2 to 5 years were investigated...
January 14, 2019: European Journal of Clinical Nutrition
Carlos A Reyes-Torres, Lilia Castillo-Martínez, Roberto Reyes-Guerrero, Aniela G Ramos-Vázquez, Mónica Zavala-Solares, Lorena Cassis-Nosthas, Aurora E Serralde-Zúñiga
BACKGROUND/OBJECTIVES: Oropharyngeal dysphagia (OD) is a common problem in elderly population that negatively affects the oral intake and body composition resulting in clinical complications as malnutrition and dehydration. The aim of this study was to design, implement, and evaluate the effect of texture-modified foods and thickened drinks diet, with nectar or pudding viscosity and controlled bolus volume in older adults with OD on body composition and oral intake. SUBJECTS/METHODS: Randomized clinical trial, simple blind...
January 14, 2019: European Journal of Clinical Nutrition
Felipe V C Machado, Lorena P Schneider, Jéssica Fonseca, Letícia F Belo, Camila Bonomo, Andrea A Morita, Karina C Furlanetto, Josiane M Felcar, Antenor Rodrigues, Frits M E Franssen, Martijn A Spruit, Fabio Pitta, Nidia A Hernandes
BACKGROUND/OBJECTIVES: Abnormal body composition is an independent determinant of COPD outcomes. To date, it is already known that patient stratification into body composition phenotypes are associated with important outcomes, such as exercise capacity and inflammation, but there are no data comparing physical activity and muscle strength among these phenotypes. Thus, the aim of this study was to compare clinical characteristics and physical function in patients with COPD stratified into body composition phenotypes...
January 14, 2019: European Journal of Clinical Nutrition
Jelena Meinilä, Mia-Maria Perälä, Hannu Kautiainen, Satu Männistö, Noora Kanerva, Nitin Shivappa, James R Hébert, Patricia Iozzo, Maria Angela Guzzardi, Johan G Eriksson
BACKGROUND: Telomeres are repeats of DNA that contain the sequence TTAGGG at the ends of each chromosome, and their function is to protect DNA from damage. Little evidence exists regarding the relationship between dietary patterns and telomere length, especially derived applying longitudinal design. The aim was to study if overall dietary pattern is associated with leukocyte telomere length (LTL) or faster telomere attrition or both. METHODS: The setting was longitudinal and observational...
January 14, 2019: European Journal of Clinical Nutrition
Saeede Saadati, Behzad Hatami, Zahra Yari, Mohammad Amin Shahrbaf, Sareh Eghtesad, Asieh Mansour, Hossein Poustchi, Mehdi Hedayati, Morteza Aghajanpoor-Pasha, Amir Sadeghi, Azita Hekmatdoost
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a major global health problem. The most common cause of death in these patients is due to cardiovascular disorders. The aim of this study was to examine the effects of curcumin supplementation on cardiovascular risk factors in patients with NAFLD. METHODS AND MATERIALS: In this randomized, placebo-controlled, clinical trial, fifty two patients with NAFLD were randomly assigned to receive life style recommendations plus either 1500 mg curcumin or placebo for 12 weeks...
January 4, 2019: European Journal of Clinical Nutrition
Hirohito Muramatsu, Tetsuro Okamoto, Tomoko Kubo, Midori Matsuki, Sonomi Iwata, Akemi Fujiwara, Naoya Miyajima, Hidetoshi Inomata, Tomokazu Hoshi, Yoshiro Goto
BACKGROUND/OBJECTIVES: This historical control study examined the differences in the incidence of postoperative pneumonia between patients administered liquid and semi-solid nutrients after percutaneous endoscopic gastrostomy (PEG). SUBJECTS/METHODS: The medical records of adult patients who underwent PEG between March 1999 and March 2014 were investigated. The patients were administered either liquid or semi-solid nutrient and examined for gastroesophageal reflux via radiography after PEG...
January 4, 2019: European Journal of Clinical Nutrition
Debora M Silva, Nayara P Queiroz, Ana Tereza V S Freitas, Marisa Passarelli, Flávia Campos Corgosinho, Maria do Rosário G Peixoto
BACKGROUND: Advanced glycation end products (AGEs) are elevated in patients with renal failure and may potentially affect skeletal muscle. The aim of this study was to evaluate whether serum concentrations of AGEs are associated with muscle strength in hemodialysis (HD) patients, since this association is not clear in the literature. METHODS: This research has a cross-sectional design and included 96 patients on hemodialysis treatment (20-69 years). Serum AGEs (ELISA), three-day dietary records, anthropometric and bioimpedance variables and handgrip strength (HGS) were analysed...
January 3, 2019: European Journal of Clinical Nutrition
Yue Yue Zhang, Li Jie Gu, Juan Huang, Min Chao Cai, Hong Lei Yu, Wei Zhang, Jin Fang Bao, Wei Jie Yuan
BACKGROUND/OBJECTIVES: Long-lived proteins and organelles, such as mitochondria and the sarcoplasmic reticulum, are degraded by autophagy. However, the specific role of autophagy in chronic kidney disease (CKD) muscle atrophy is still undefined. SUBJECTS/METHODS: This was a cross-sectional study with 20 subjects and 11 controls. Autophagy induction was studied in human skeletal muscle biopsies from CKD patients and controls by comparing the cross-sectional areas of muscle fibers, protein, and mRNA expression of autophagy-related genes and the appearance of autophagosomes...
January 3, 2019: European Journal of Clinical Nutrition
Cheng Chi, Nicholas Buys, Cheng Li, Jing Sun, Chenghong Yin
BACKGROUND/OBJECTIVES: Prebiotics are increasingly recognized as an effective measure to promote health and prevent adverse health outcomes in preterm infants. We aimed to systematically review the randomized controlled trials (RCTs) in this area. SUBJECTS/METHODS: Relevant studies from January 2000 to June 2018 were searched and selected from PubMed, Medline, Scopus, and the Cochrane Library. RCTs were included if they involved preterm infant participants, included a prebiotic intervention group, measured incidence of sepsis, feeding intolerance, mortality, time to full enteral feeding, necrotizing enterocolitis (NEC), length of hospital stay, and stool frequency as outcomes...
December 19, 2018: European Journal of Clinical Nutrition
Seungho Ryu, Nitin Shivappa, Nicola Veronese, Minsoo Kang, Joshua R Mann, James R Hébert, Michael D Wirth, Paul D Loprinzi
OBJECTIVE: The objective of this study was to evaluate secular trends in Dietary Inflammatory Index (DII) scores in the United States between 1999 and 2014. METHODS: Data from adults over 19 years from the 1999 to 2014 National Health and Nutrition Examination Survey (N = 39,191) were used. DII scores, at each 2-year cycle, were evaluated from a 24-h recall, including 26 food parameters for DII calculation. Analyses were conducted in 2018. RESULTS: For the entire sample, there was a quadratic trend (Ptrend  < 0...
December 12, 2018: European Journal of Clinical Nutrition
Rachael M Taylor, Roger Smith, Clare E Collins, Tiffany-Jane Evans, Alexis J Hure
BACKGROUND: It is hypothesised that epigenetic mechanisms including DNA methylation may underlie the relationship between early-life nutrition and child cognitive outcomes. This study aimed to identify dietary patterns associated with the intake of one-carbon metabolism nutrients in children aged 2-3 years. METHODS: A validated 120-item semi-quantitative food frequency questionnaires at 2-3 years of age were used to estimate the intake of one-carbon metabolism nutrients (methionine, folate, choline and vitamins B2, B6, B12) and to quantify mean number of serves consumed of the food groups specified by the Australian Guide to Healthy Eating (AGHE)...
December 11, 2018: European Journal of Clinical Nutrition
Michael F Aktas, Anja Mähler, Michael Hamm, Gabriele Perger, Frank Simon, Joachim Westenhöfer, Friedrich C Luft, Michael Boschmann
Obesity, metabolic syndrome, and type-2 diabetes mellitus are common in Muslim patients living in Germany, most of whom are of Turkish origin. Lifestyle interventions must be tailored to religion and ethnicity. We tested the body weight-reducing effect of a 30% calorie-reduced intake diet, adjusted to individual energy expenditure, eating habits, and food preferences in a Turkish-background cohort. Eighty subjects were randomized to activity advice only or to a step-count device to monitor and document physical activity before and after the 12-week intervention...
December 11, 2018: European Journal of Clinical Nutrition
Klaas R Westerterp
No abstract text is available yet for this article.
December 6, 2018: European Journal of Clinical Nutrition
Elizabeth A Lundeen, Jennifer N Lind, Kristie E N Clarke, Nancy J Aburto, Cholpon Imanalieva, Tursun Mamyrbaeva, Asel Ismailova, Arnold Timmer, Ralph D Whitehead, Larissa Praslova, Galina Samohleb, Muktar Minbaev, O Yaw Addo, Mary K Serdula
BACKGROUND/OBJECTIVES: In 2009, the Ministry of Health of Kyrgyzstan launched a national Infant and Young Child Nutrition (IYCN) program which included point-of-use fortification of foods with micronutrient powders (MNP) containing iron, vitamin A, and other micronutrients. Caretakers of children aged 6-23 months were given 30 sachets of MNP every 2 months. Micronutrient surveys were conducted in 2009 and 2013. The objective of the study was to compare the prevalence of anemia and deficiencies of iron and vitamin A among children aged 6-29 months prior to the MNP program (2009) with those after full implementation (2013)...
December 6, 2018: European Journal of Clinical Nutrition
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