Dalia Omran, Rania A Zayed, Mohammed M Nabeel, Lamiaa Mobarak, Zeinab Zakaria, Azza Farid, Mohamed Hassany, Sameh Saif, Muhammad Mostafa, Omar Khalid Saad, Ayman Yosry
Stage of liver fibrosis is critical for treatment decision and prediction of outcomes in chronic hepatitis C (CHC) patients. We evaluated the diagnostic accuracy of transient elastography (TE)-Fibroscan and noninvasive serum markers tests in the assessment of liver fibrosis in CHC patients, in reference to liver biopsy. One-hundred treatment-naive CHC patients were subjected to liver biopsy, TE-FibroScan, and eight serum biomarkers tests; AST/ALT ratio (AAR), AST to platelet ratio index (APRI), age-platelet index (AP index), fibrosis quotient (FibroQ), fibrosis 4 index (FIB-4), cirrhosis discriminant score (CDS), King score, and Goteborg University Cirrhosis Index (GUCI)...
April 9, 2018: Viral Immunology