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Journal of Clinical Epidemiology

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https://www.readbyqxmd.com/read/28214550/improving-the-reporting-of-randomized-pilot-and-feasibility-trials
#1
Peter Craig
No abstract text is available yet for this article.
February 15, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28188899/trends-in-studies-of-pharmacologic-interventions-published-in-high-impact-medical-journals-2004-2013
#2
Laura L Hester, Charles Poole, Elizabeth A Suarez, Jane S Der, Olivia G Anderson, Kathryn G Almon, Avanti V Shirke, M Alan Brookhart
No abstract text is available yet for this article.
February 7, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28188898/rating-of-included-trials-on-the-efficacy-effectiveness-spectrum-rites-development-of-a-new-tool-for-systematic-reviews
#3
L Susan Wieland, Brian M Berman, Douglas G Altman, Jürgen Barth, Lex M Bouter, Christopher R D'Adamo, Klaus Linde, David Moher, C Daniel Mullins, Shaun Treweek, Sean Tunis, Danielle A van der Windt, Merrick Zwarenstein, Claudia Witt
BACKGROUND: Randomized trials may be designed to provide evidence more strongly related to efficacy or effectiveness of an intervention. When systematic reviews are used to inform clinical or policy decisions, it is important to know the efficacy-effectiveness nature of the included trials. OBJECTIVE: To develop a tool to characterize randomized trials included in a systematic review on an efficacy-effectiveness continuum. METHODS: We extracted rating domains and descriptors from existing tools, and used a modified Delphi procedure to condense the domains and develop a new tool...
February 7, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28188897/unmasking-survival-biases-in-observational-treatment-studies-of-influenza-patients
#4
Martin Wolkewitz, Martin Schumacher
BACKGROUND: Several observational studies reported that Oseltamivir (Tamiflu) reduced mortality in infected and hospitalized patients. Due to the restriction of observation to hospital stay and time-dependent treatment assignment, such findings were prone to common types of survival bias (length, time-dependent and competing risk bias). METHODS: British hospital data from the FLU-CIN study group were used which included 1391 patients with confirmed pandemic influenza A/H1N1 2009 infection...
February 7, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28167144/-bootstrap-imputation-with-a-disease-probability-model-minimized-bias-from-misclassification-due-to-administrative-database-codes
#5
Carl van Walraven
OBJECTIVE: Diagnostic codes used in administrative databases cause bias due to misclassification of patient disease status. It is unclear which methods minimize this bias. STUDY DESIGN: Serum creatinine measures were used to determine severe renal failure status in 50,074 hospitalized patients. The true prevalence of severe renal failure and its association with covariates were measured. These were compared to results for which renal failure status was determined using surrogate measures including: i) diagnostic codes; ii) categorization of probability estimates of renal failure determined from a previously validated model; or iii) bootstrap methods imputation of disease status using model-derived probability estimates...
February 3, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28161452/odds-ratios-are-not-conditional-risk-ratios
#6
Anders Huitfeldt
No abstract text is available yet for this article.
February 1, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28147235/systematic-reviews-of-therapeutic-interventions-frequently-consider-patient-important-outcomes
#7
Hayet Ameur, Philippe Ravaud, Florence Fayard, Carolina Riveros, Agnes Dechartres
OBJECTIVE: To determine whether recently published and ongoing systematic reviews of therapeutic interventions assess patient-important outcomes. STUDY DESIGN AND SETTING: For this methodological review, we searched MEDLINE via PubMed for recently published systematic reviews and PROSPERO for ongoing systematic reviews. We selected systematic reviews with meta-analyses of randomized controlled trials. We extracted all outcomes defined in the Methods section and categorized them...
January 29, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28137672/multiple-imputation-was-a-valid-approach-to-estimate-absolute-risk-from-a-prediction-model-based-on-case-cohort-data
#8
Kristin Mühlenbruch, Olga Kuxhaus, Romina di Giuseppe, Heiner Boeing, Cornelia Weikert, Matthias B Schulze
OBJECTIVE: To compare weighting methods for Cox regression and multiple imputation (MI) in a case-cohort study in the context of risk prediction modelling. STUDY DESIGN AND SETTING: Based on the European Prospective Investigation into Cancer and Nutrition Potsdam study (EPIC-Potsdam), we estimated risk scores to predict incident type 2 diabetes using full cohort data and case-cohort data assuming missing information on waist circumference outside the case-cohort (∼90%) ...
January 27, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28137671/understanding-pragmatism-and-precis-2
#9
Merrick Zwarenstein, Shaun Treweek, Kirsty Loudon
No abstract text is available yet for this article.
January 27, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28126599/complex-self-management-interventions-in-chronic-disease-unravelled-a-review-of-lessons-learned-from-an-individual-patient-data-meta-analysis
#10
REVIEW
Nini H Jonkman, Rolf H H Groenwold, Jaap C A Trappenburg, Arno W Hoes, Marieke J Schuurmans
OBJECTIVES: Meta-analyses using individual patient data (IPD) rather than aggregated data are increasingly applied to analyze sources of heterogeneity between trials and have only recently been applied to unravel multicomponent, complex interventions. This study reflects on methodological challenges encountered in two IPD meta-analyses on self-management interventions in patients with heart failure or chronic obstructive pulmonary disease. STUDY DESIGN AND SETTING: Critical reflection on prior IPD meta-analyses and discussion of literature...
January 23, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28126598/reporting-of-data-monitoring-boards-in-publications-of-randomized-clinical-trials-is-often-deficient-acttion-systematic-review
#11
Jennifer S Gewandter, Rachel A Kitt, Matthew R Hunsinger, Joseph Poku, Jacqueline Lozano, Jenna Chaudari, Scott Evans, Robert A Gross, Michael P McDermott, Michael C Rowbotham, Dennis C Turk, Robert H Dworkin
OBJECTIVE: To examine whether primary reports of randomized clinical trials (RCTs) in six high-impact, general medical journals reported (1) whether or not a Data Monitoring Committee/Data and Safety Monitoring Board (DMC/DSMB) was used and (2) the composition of the responsibilities of the reported DSMB/DMCs. STUDY DESIGN AND SETTING: Systematic review of RCTs published in 2014 in Annals of Internal Medicine, BMJ, NEJM, JAMA, JAMA Internal Medicine, and Lancet...
January 23, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28115256/requesting-a-unique-personal-identifier-or-providing-a-souvenir-incentive-did-not-affect-overall-consent-to-health-record-linkage-evidence-from-an-rct-nested-within-a-cohort
#12
Michael Y Ni, Tom K Li, Rex W H Hui, Ian McDowell, Gabriel M Leung
OBJECTIVE: It is unclear if unique personal identifiers should be requested from participants for health record linkage: this permits high-quality data linkage but at the potential cost of lower consent rates due to privacy concerns. STUDY DESIGN AND SETTING: Drawing from a sampling frame based on the FAMILY Cohort, using a 2 × 2 factorial design, we randomly assigned 1,200 participants to (1) request for Hong Kong Identity Card number (HKID) or no request and (2) receiving a souvenir incentive (valued at USD4) or no incentive...
January 20, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28108353/rasch-analysis-supported-the-construct-validity-of-self-report-measures-of-activity-and-participation-derived-from-patient-ratings-of-the-icf-low-back-pain-core-set
#13
Karl S Bagraith, Jenny Strong, Pamela J Meredith, Steven M McPhail
OBJECTIVE: To investigate whether measures of activity limitations and participation restrictions with sound internal construct validity could be derived from patient ratings of the International Classification of Functioning, Disability and Health Low Back Pain Core Set (LBP-CS). STUDY DESIGN AND SETTING: The LBP-CS Self-Report Checklist (LBP-CS-SRC) was developed to permit patients to self-rate their functioning according to an extended set of activity and participation categories from the LBP-CS...
January 17, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28108352/commentary-on-epc-methods-an-exploration-of-the-use-of-text-mining-software-in-systematic-reviews
#14
Robin Paynter, Lionel L Bañez, Eileen Erinoff, Jennifer Matsuura, Shannon Potter
No abstract text is available yet for this article.
January 17, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28108351/response-to-letter-to-the-editor-by-a-huitfeldt-re-odds-ratios-deconstructed-a-new-way-to-understand-and-explain-odds-ratios-as-conditional-risk-ratios
#15
Fred M Hoppe, Daniel J Hoppe, Stephen D Walter
No abstract text is available yet for this article.
January 17, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28104463/moving-from-outcomes-to-values-to-deliver-high-quality-health-care
#16
Logan Trenaman, Nick Bansback
No abstract text is available yet for this article.
January 16, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28104462/questionnaires-used-to-assess-barriers-of-clinical-guideline-use-among-physicians-are-not-comprehensive-reliable-or-valid-a-scoping-review
#17
REVIEW
Melina L Willson, Robin Wm Vernooij, Anna R Gagliardi
OBJECTIVE: This study described the number and characteristics of questionnaires used to assess barriers of guideline use among physicians. STUDY DESIGN: A scoping review was conducted. MEDLINE and EMBASE were searched from 2005 to June 2016. English language studies that administered a questionnaire to assess barriers of guideline use among practicing physicians were eligible. Summary statistics were used to report study and questionnaire characteristics. Questionnaire content was assessed with a checklist of 57 known barriers...
January 16, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28093263/-cross-sectional-stepped-wedge-designs-always-reduce-the-required-sample-size-when-there-is-no-time-effect
#18
LETTER
Xin Zhou, Xiaomei Liao, Donna Spiegelman
No abstract text is available yet for this article.
January 16, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28093264/consort-guidelines-for-non-inferiority-trials-going-beyond-the-absolute-risk-difference
#19
Walter Palmas
No abstract text is available yet for this article.
January 13, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28093262/the-anchor-based-minimal-important-change-mic-based-on-roc-analysis-or-predictive-modeling-may-need-to-be-adjusted-for-the-proportion-of-improved-patients
#20
Berend Terluin, Iris Eekhout, Caroline B Terwee
OBJECTIVES: Patients have their individual minimal important changes (iMICs) as their personal benchmarks to determine whether a perceived health-related quality of life (HRQOL) change constitutes a (minimally) important change for them. We denote the mean iMIC in a group of patients as the "genuine MIC" (gMIC). The aims of this paper are (1) to examine the relationship between the gMIC and the anchor-based minimal important change (MIC), determined by receiver operating characteristics (ROC) analysis or by predictive modeling; (2) to examine the impact of the proportion of improved patients on these MICs; and (3) to explore the possibility to adjust the MIC for the influence of the proportion of improved patients...
January 13, 2017: Journal of Clinical Epidemiology
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