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International Journal of Geriatric Psychiatry

Breno S Diniz, Susan Fisher-Hoch, Joseph McCormick
OBJECTIVE: Depressive symptoms are common among older adults with obesity and diabetes. Nonetheless, the mechanisms for this association are not clear but may involve changes in the insulin cascade signaling. We aimed to investigate the association, and potential mediators, between obesity, insulin resistance, and depressive symptoms among older adults from a homogenous cohort of Mexican-Americans. METHODS: We included a total of 500 Mexican-American older adults assessed in the Cameron County Health Study...
September 18, 2017: International Journal of Geriatric Psychiatry
Song Lin, Huaqi Zhang, Aiguo Ma
OBJECTIVE: Several studies have shown that gout is associated with depression symptoms. In this study, a systematic review and meta-analysis was performed to explore the relationship between gout and depression. METHODS: Published articles were identified through a comprehensive review of PUBMED and EMBASE. Data from studies reporting relative risks, odds ratios, or hazard ratios comparing the risk of depression among participants who had gout versus those without gout were analyzed...
September 18, 2017: International Journal of Geriatric Psychiatry
Matthew J Hollocks, Rebecca L Brookes, Robin G Morris, Hugh S Markus
OBJECTIVE: While there are several cognitive screening tests available for the detection of cortical dementias such as Alzheimer's disease (AD), these are rarely designed to be sensitive to vascular cognitive impairment (VCI). The Brief Memory and Executive Test (BMET) is a screening measure designed to be sensitive to the cognitive profile of both VCI and AD. This study investigated the ability of the BMET to detect AD, and to differentiate between VCI and AD. METHODS: This study included 150 patients, with either SVD, both with (n = 48) and without VCI (n = 51), or AD (N = 51) and 51 healthy controls...
September 7, 2017: International Journal of Geriatric Psychiatry
Angelina R Sutin, Yannick Stephan, Martina Luchetti, Antonio Terracciano
OBJECTIVE: Behavioral and psychological symptoms of dementia (BPSD) are among the most challenging aspects of Alzheimer disease for patients and their families. Previous studies have found associations between informant-reported retrospective personality and BPSD; we test whether prospective, self-reported personality predicts who will experience these symptoms. METHODS: Deceased participants from the Health and Retirement Study who had evidence of cognitive impairment at the end of life (N = 1988) were selected to examine whether self-reported five-factor model personality traits, measured up to 8 years before death, were associated with proxy-reported BPSD...
September 4, 2017: International Journal of Geriatric Psychiatry
Ryota Sakurai, Kenji Ishii, Naoko Sakuma, Masashi Yasunaga, Hiroyuki Suzuki, Yoh Murayama, Mariko Nishi, Hayato Uchida, Shoji Shinkai, Yoshinori Fujiwara
OBJECTIVES: A growing body of literature indicates that social engagements, such as intergenerational programs, are effective strategies to improve a range of cognitive abilities. The present study examined whether the intergenerational program-REPRINTS-prevents age-related hippocampal atrophy. METHODS: After comprehensive baseline assessment, participants were allowed to decide whether to participate in the REPRINTS intervention or in the control group, which required only completion of assessments...
August 31, 2017: International Journal of Geriatric Psychiatry
Naaheed Mukadam, Fatima Jichi, David Green, Gill Livingston
OBJECTIVES: We wished to clarify the link between bilingualism and cognitive decline, and examine whether improved executive function due to bilingualism may be a factor in preventing cognitive decline. METHODS: We used the Australian Longitudinal Study of Ageing which collected data on 2087 participants aged over 65 over 20 years. We compared baseline demographics, health, and social characteristics between bilingual and non-bilingual participants. We used linear mixed models analysis to explore the effect of bilingualism on MMSE score over time and linear regression to explore the effect of bilingualism on baseline MMSE scores, controlling for pre-specified potential confounders...
August 31, 2017: International Journal of Geriatric Psychiatry
Madeleine Liljegren, Maria Landqvist Waldö, Elisabet Englund
OBJECTIVE: To investigate the prevalence of physical aggression among patients with dementia of different types and to analyze potential differences in clinical traits, in terms of singular or repetitive behavior and occurrence in early or late stage of the disease. We also aimed at examining against whom the physical aggression was exerted. METHODS: We included 281 cases with a neuropathological dementia diagnosis from the brain bank at the Department of Pathology, Lund University, for this retrospective medical records review...
August 31, 2017: International Journal of Geriatric Psychiatry
Miharu Nakanishi, Kaori Endo, Kayo Hirooka, Eva Granvik, Lennart Minthon, Katarina Nägga, Atsushi Nishida
Little is known about the effectiveness of a psychosocial behaviour management programme on home-dwelling people with dementia. We developed a Behaviour Analytics & Support Enhancement (BASE) programme for care managers and professional caregivers of home care services in Japan. We investigated the effects of BASE on challenging behaviour of home-dwelling people with dementia. METHODS: A cluster-randomized controlled trial was conducted with home care providers from 3 different districts in Tokyo...
August 31, 2017: International Journal of Geriatric Psychiatry
Raúl López-Antón, Juan Ramón Barrada, Javier Santabárbara, Mar Posadas-de Miguel, Luís Agüera, Carmen Burillo, Manuel Franco, Jorge López-Álvarez, Pilar Mesa, Roberto Petidier, Miguel Ángel Quintanilla, Bernabé Robles-Del Olmo, Tirso Ventura, Maya Semrau, Norman Sartorius, Antonio Lobo
OBJECTIVE: The IDEAL Schedule was developed for staging "care needs" in patients with dementia. We here aim to validate the Spanish version, further test its psychometric properties and explore a latent construct for "care needs". METHODS: A multicenter study was done in 8 dementia care facilities across Spain. Patients referred with a reliable ICD-10 diagnosis of dementia (n = 151) were assessed with the IDEAL Schedule by pairs of raters. Inter-rater reliability (intra-class correlation [ICC] coefficients), internal consistency (Cronbach's alpha), and factor analysis were calculated...
August 31, 2017: International Journal of Geriatric Psychiatry
Kazuki Uemura, Hyuma Makizako, Sangyoon Lee, Takehiko Doi, Songchul Lee, Kota Tsutsumimoto, Hiroyuki Shimada
BACKGROUND: It remains unclear what kinds of behavior prevent the development of geriatric depression. This study aimed to elucidate behavioral predictors of increased depressive symptoms in older adults focusing on gender differences. METHODS: A total of 3106 community-dwelling older people aged older than or equal to 65 years without depressive symptoms at baseline participated. The 15-item Geriatric Depression Scale was used to assess depressive symptoms with a score of 6 or more at baseline and 15 month follow-up...
August 25, 2017: International Journal of Geriatric Psychiatry
Hilde Verbeek, Angela Worden, Mark Wilberforce, Christian Brand, Sue Tucker, Michele Abendstern, David Challis
OBJECTIVE: Integrated community mental health teams (CMHTs) are a key component of specialist old age psychiatry services internationally. However, in England, significant shifts in policy, including a focus on dementia and age inclusive services, have influenced provision. This study portrays teams in 2009 against which subsequent service provision may be compared. METHODS: A bespoke national postal survey of CMHT managers collected data on teams' structure, composition, organisation, working practices, case management, and liaison activities...
August 23, 2017: International Journal of Geriatric Psychiatry
Wei Zhang, Wo Wang, Li Kuang
BACKGROUND: The aim of this study is to evaluate whether lower serum levels of insulin-like growth factor 1 (IGF-1) in the acute phase of ischemic stroke are associated with higher risk of post-stroke depression (PSD) over a 1-year period. METHODS: The subjects were first-ever acute ischemic stroke (AIS) patients who were hospitalized from July 1, 2014 to August 31, 2015. The study also included 120 age-matched and sex-matched healthy controls from the same geographical area...
August 23, 2017: International Journal of Geriatric Psychiatry
Yonghai Dong, Xiaodan Chen, Yun Liu, Yan Shu, Ting Chen, Lei Xu, Meng Li, Xihong Guan
OBJECTIVE: Whether low-serum vitamin E increases the risk of Alzheimer disease (AD) in older people remains inconclusive. This meta-analysis aims to synthesize evidence-based case-control studies to evaluate the association between serum vitamin E and the risk of AD. METHODS: Potentially relevant studies were selected through PubMed, Embase, Wanfang, Chongqing VIP, and China National Knowledge Infrastructure databases by using the core terms Vitamin E/alpha-tocopherol and Alzheime's disease/senile dementia/AD in the titles, abstracts, and keywords of the articles...
August 23, 2017: International Journal of Geriatric Psychiatry
Yu-Jung Wei, Linda Simoni-Wastila, Jennifer S Albrecht, Ting-Ying Huang, Patience Moyo, Bilal Khokhar, Ilene Harris, Patricia Langenberg, Giora Netzer, Susan W Lehmann
The effect of treating comorbid depression to achieve optimal management of chronic obstructive pulmonary disease (COPD) has not yet empirically tested. We examined the association between antidepressant treatment and use of and adherence to COPD maintenance medications among patients with new-onset COPD and comorbid depression. METHODS: Using 2006-2012 Medicare data, this retrospective cohort study identified patients with newly diagnosed COPD and new-onset major depression. Two exposures-antidepressant use (versus non-use) and adherence measured by proportion of days covered (PDC) (PDC ≥0...
August 22, 2017: International Journal of Geriatric Psychiatry
Marco Túlio Gualberto Cintra, Rafaela Teixeira Ávila, Thayana Oliveira Soares, Luciana Cristina Matos Cunha, Katia Daniela Silveira, Edgar Nunes de Moraes, Kaique Roger Simas, Renato Bragança Fernandes, Denise Utsch Gonçalves, Nilton Alves de Rezende, Maria Aparecida Camargos Bicalho
OBJECTIVE: To compare the results of neuropsychological tests, evoked potentials N200 and P300 and polymorphisms of ApoE and BDNF rs6265 between patients with normal cognition and those with mild cognitive impairment (MCI) and Alzheimer's dementia (AD). METHODS: This is a cross-sectional study of elderly individuals with normal cognition and those with MCI and AD, who were submitted to evoked potential tests (N200 and P300) by means of hearing stimuli based on the auditory oddball paradigm...
August 22, 2017: International Journal of Geriatric Psychiatry
Fan Yang, Piers Dawes, Iracema Leroi, Brenda Gannon
OBJECTIVE: Knowledge is limited about the standardised instruments used to collect resource use and quality of life data alongside trials of dementia interventions. This review aimed to identify the trials using such instruments in order to guide the design of future trial-based cost-effectiveness studies. METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement, this review examined all original, peer-reviewed research in major databases and general searches published until June 2017, including randomised clinical trials, pilot studies, or feasibility studies about interventions for older adults with dementia or cognitive impairment...
August 10, 2017: International Journal of Geriatric Psychiatry
Daniel C Mograbi, Robin G Morris, Helenice Charchat Fichman, Camila Assis Faria, Maria Angélica Sanchez, Pricila C C Ribeiro, Roberto Alves Lourenço
OBJECTIVE: Previous studies have indicated that dementia and depression have a considerable impact on the functional capacity of older adults, also influencing awareness about ability. The purpose of the current study was to investigate the impact of dementia, depression and awareness on activities of daily living (ADL) in a sample from a middle-income country. METHODS: The current study explored impairments in basic, instrumental and advanced ADL using a factorial design comparing four groups: people with dementia and depression, people with dementia without depression, older adults with depression but no dementia and healthy older adults...
August 8, 2017: International Journal of Geriatric Psychiatry
Nicola Veronese, Ai Koyanagi, Brendon Stubbs, Marco Solmi, Michele Fornaro, Brisa F Fernandes, Christoph Muller, Trevor Thompson, André F Carvalho, Stefania Maggi
OBJECTIVE: Aspirin exhibits anti-atherosclerotic and anti-inflammatory properties-two potential risk factors for depression. The relationship between aspirin use and depression, however, remains unclear. We investigated whether the aspirin use is associated with a decreased incidence of depressive symptoms in a large North American cohort. METHODS: Data from the Osteoarthritis Initiative dataset, a multicenter, longitudinal study on community-dwelling adults was analyzed...
August 6, 2017: International Journal of Geriatric Psychiatry
Karen L Fortuna, Matthew C Lohman, Martha L Bruce, Stephen J Bartels
OBJECTIVE: The objective of the study was to compare the predictive utility of three commonly used functioning measures for people with serious mental illness in the prediction of independent living status. METHODS: We conducted a secondary data analysis from the Helping Older People Experience Success study with adults aged 50 years and older with a diagnosis of bipolar disorder, schizoaffective disorder, schizophrenia, or major depressive disorder (N = 183)...
August 4, 2017: International Journal of Geriatric Psychiatry
Sahdia Parveen, Heather Blakey, Jan R Oyebode
OBJECTIVES: The Alzheimer's Society has culturally adapted an Information Programme for South Asian families (IPSAF) who support an individual living with dementia. The objectives of this evaluation were to establish whether IPSAF had an immediate and medium-term impact on those who attended and how it impacted on the wider family and the person with dementia. METHODS: An inclusive, pluralistic approach was adopted. Seven focus groups were conducted with 42 participants, and 37 participated in a pre-post knowledge quiz...
August 2, 2017: International Journal of Geriatric Psychiatry
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