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Archives of Gynecology and Obstetrics

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https://www.readbyqxmd.com/read/29159540/is-fertility-preservation-safe-for-adult-non-metastatic-gynecologic-rhabdomyosarcoma-patients-systematic-review-and-pooled-survival-analysis-of-137-patients
#1
REVIEW
Maha At Elsebaie, Zeinab Elsayed
PURPOSE: Recently, conservative approaches such as wide local excisions and neoadjuvant chemotherapy are being considered to select young adult females with gynecologic RMS who have strong desire to preserve fertility. This analysis aims to identify prognosticators affecting survival outcomes and defining potential candidacy for fertility-preservation. Another focus is to explore the role of chemotherapy in reducing the need for aggressive surgery and the role of radiotherapy in decreasing rates of local failure...
November 20, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29151230/intentional-placental-removal-on-suspicious-placenta-accreta-spectrum-still-prohibited
#2
Shigeki Matsubara, Hironori Takahashi
INTRODUCTION: Intentional placental removal for abnormally invasive placenta (AIP) is fundamentally abandoned at planned surgery for it. Whether this holds true even after recent introduction of various hemostatic procedures is unclear. MATERIALS AND METHODS: We discussed on this issue based on our own experiences and also on the recent reports on various hemostatic procedures. RESULTS: Studies directly answering this question have been lacking...
November 18, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29143937/reply-to-retained-placenta-accreta-with-marked-vascularity-uterine-artery-pseudoaneurysm-and-placental-polyp-overlapping-clinical-entities
#3
LETTER
Akihiro Takeda, Wataru Koike
No abstract text is available yet for this article.
November 16, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29143936/retained-placenta-accreta-with-marked-vascularity-uterine-artery-pseudoaneurysm-and-placental-polyp-overlapping-clinical-entities
#4
LETTER
Shigeki Matsubara, Hironori Takahashi, Tatsuya Suzuki
No abstract text is available yet for this article.
November 16, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29143102/diagnostic-performance-of-hpv-e6-e7-mrna-assay-for-detection-of-cervical-high-grade-intraepithelial-neoplasia-and-cancer-among-women-with-ascus-papanicolaou-smears
#5
Chenchen Ren, Yuanhang Zhu, Li Yang, Xiaoan Zhang, Ling Liu, Chunying Ren
PURPOSE: The aim of this study was to investigate the clinical performance of high risk (HR) HPV E6/E7 mRNA assay in detecting cervical high-grade intraepithelial neoplasia and cancer among women with atypical squamous cells of undetermined significance (ASCUS) Papanicolaou (Pap) smears. METHODS: A total of 160 patients with ASCUS who underwent HR-HPV DNA assay, HR-HPV E6/E7 mRNA assay and colposcopy biopsy at Third Affiliated Hospital of Zhengzhou University, China, from December 2015 to March 2017, were enrolled...
November 15, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29143101/candidate-biomarkers-in-the-cervical-vaginal-fluid-for-the-self-diagnosis-of-cervical-precancer
#6
REVIEW
Xaveer Van Ostade, Martin Dom, Wiebren Tjalma, Geert Van Raemdonck
PURPOSE: Despite improvement in vaccines against human papilloma virus (HPV), the causative agent of cervical cancer, screening women for cervical precancer will remain indispensable in the coming 30-40 years. A simple test that could be performed at home or at a doctor's practice and that informs the woman whether she is at risk would significantly help make a broader group of patients who aware that they need medical treatment. Cervical vaginal fluid (CVF) is a body fluid that is very well suited for such a test...
November 15, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29128980/reducing-the-spread-of-occult-uterine-sarcoma-at-the-time-of-minimally-invasive-gynecologic-surgery
#7
Marron Wong, Rudy Leon De Wilde, Keith Isaacson
PURPOSE: This review covers the most recent evidence to discuss the incidence of occult uterine sarcoma, whether morcellation increases tumor dissemination or mortality, and whether there is a difference between different types of morcellation. We will also discuss techniques to reduce the spread of an undiagnosed uterine sarcoma. METHOD: A comprehensive literature search was made in Pubmed, Medline, the Cochrane Library, and Google Scholar for articles related to the incidence of occult uterine sarcoma after morcellation...
November 11, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29116461/investigation-of-the-clinical-features-of-lower-uterine-segment-carcinoma-association-with-advanced-stage-disease-and-indication-of-poorer-prognosis
#8
Ai Miyoshi, Serika Kanao, Hirokazu Naoi, Hirofumi Otsuka, Takeshi Yokoi
PURPOSE: We retrospectively analyzed the differential clinical features and prognosis of endometrial carcinomas arising from the lower uterus, which are reported to have a poorer prognosis than those arising from the upper uterus. METHODS: 246 patients with endometrial carcinoma who underwent surgery were entered as subjects. RESULTS: Twenty-three were classified as having lower uterine segment carcinomas (LUSC); the remaining 223 were upper uterine segment carcinomas (UUSC)...
November 7, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29110117/successful-treatment-of-acute-promyelocytic-leukemia-in-pregnancy-with-single-agent-all-trans-retinoic-acid
#9
REVIEW
Cordula M Nellessen, Viktor Janzen, Karin Mayer, Giulia Giovannini, Ulrich Gembruch, Peter Brossart, Waltraut M Merz
PURPOSE: The diagnosis of acute promyelocytic leukemia (APL) in pregnancy is an uncommon, life-threatening emergency. Choice of treatment and management of complications are challenging. METHODS: We report the case of a patient with diagnosis of APL at gestational age (GA) 24 + 4. We describe the interdisciplinary management during pregnancy and delivery and provide a 2-year follow-up. Existing reports on APL in pregnancy are summarized. RESULTS: Single-agent induction therapy with all-trans retinoic acid (ATRA) was started and resulted in normalization of blood cell counts after 32 days...
November 6, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29103195/maternal-sepsis-in-the-era-of-genomic-medicine
#10
REVIEW
C Kouskouti, N Evangelatos, A Brand, F Kainer
PURPOSE: Maternal sepsis remains one of the leading causes of direct and indirect maternal mortality both in high- and low-income environments. In the last two decades, systems biology approaches, based on '-omics' technologies, have started revolutionizing the diagnosis and management of the septic syndrome. The scope of this narrative review is to present an overview of the basic '-omics' technologies, exemplified by cases relevant to maternal sepsis. METHODS: Narrative review of the new '-omics' technologies based on a detailed review of the literature...
November 4, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29103194/astragalus-polysaccharides-increase-the-sensitivity-of-skov3-cells-to-cisplatin
#11
Caihong Li, Li Hong, Cheng Liu, Jie Min, Ming Hu, Wenjun Guo
BACKGROUND: Multidrug resistance in malignant tumours hinders the treatment of tumours. Studies showed that astragalus polysaccharides (APS), one major active ingredient of astragalus, enhanced the sensitivity of non-small cell lung cancer and liver cancer cells to chemotherapeutic drug. However, the effect of APS on ovarian cancer is still unclear. In this study, we will examine the sensitizing effect of APS on SKOV3 cells to cisplatin and explore the possible mechanism. METHODS: MTT assay was employed to examine the viability of SKOV3 after treatment with APS and cisplatin...
November 4, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29101609/assessment-of-ovarian-function-after-chemotherapy-in-women-with-early-and-locally-advanced-breast-cancer-from-serbia
#12
Emina Malisic, Snezana Susnjar, Jelena Milovanovic, Natasa Todorovic-Rakovic, Vesna Kesic
PURPOSE: Among harmful effects of chemotherapy is the reduction of ovarian function. The aim was to determine the serum levels of FSH, LH, estradiol and AMH after chemotherapy followed by endocrine therapy in breast cancer patients. METHODS: The study included 40 premenopausal hormone receptor-positive breast cancer patients aged 33-50 years. Anthracycline-based chemotherapy received 14/40 while anthracycline-taxane combination received 26/40 of patients, followed by tamoxifen (30/40) or tamoxifen plus goserelin (10/40)...
November 3, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29101608/failed-manual-removal-of-the-placenta-after-vaginal-delivery
#13
Johanna Bjurström, Sally Collins, Jens Langhoff-Roos, Karin Sundberg, Annemette Jørgensen, Johannes J Duvekot, Lene Groenbeck
PURPOSE: A retained placenta after vaginal delivery where manual removal of placenta fails is a clinical challenge. We present six cases that illustrate the heterogeneity of the condition and discuss the etiology and terminology as well as the clinical management. METHODS: Members of the European Working group on Abnormally Invasive Placenta (EW-AIP) were invited to report all recent cases of retained placenta that were not antenatally suspected to be abnormally adherent or invasive, but could not be removed manually despite several attempts...
November 3, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29098421/what-is-the-accuracy-of-frozen-section-in-the-diagnosis-of-mucinous-ovarian-tumours-a-9-year-review-of-performance-in-a-greek-tertiary-referral-centre
#14
Anastasios Tranoulis, Nikolaos Thomakos, Maria Sotiropoulou, Alexandros Rodolakis
PURPOSE: This retrospective study aimed to evaluate the diagnostic accuracy of the intra-operative frozen sections (FS) of mucinous ovarian tumours (mOT). METHODS: Between 2007 and 2015, a total of 105 mucinous ovarian samples were collected during laparotomy. The intra-operative FS accuracy was evaluated and potential factors correlated with increased inaccuracy assessed using both univariate and multivariate analysis. RESULTS: The overall FS accuracy was 82...
November 2, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29086015/the-role-of-serum-adamts-1-and-aggrecan-on-polycystic-ovary-syndrome-in-adolescents-and-younger-aged-females
#15
Esra Nur Tola, Nadiye Dugan Koroglu, Serenat Eris Yalcin, Hilmi Baha Oral
PURPOSE: The aim of this study was to analyze serum a disintegrin-like and metalloproteinase with thrombospondin-type motifs-1 (ADAMTS-1) and aggrecan levels in adolescents and younger-aged females with polycystic ovary syndrome (PCOS) compared with ovulatory controls to determine whether these are potential markers for the prediction of PCOS diagnosis. We also aimed to determine whether they could predict the development of clinical implications associated with PCOS. METHOD: PCOS (n = 49) and ovulatory age-matched controls (n = 41) (mean age, 18...
October 31, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29082423/obstetric-and-perinatal-outcomes-in-subfertile-patients-who-conceived-following-low-technology-interventions-for-fertility-enhancement-a-comprehensive-review
#16
Stefano Palomba, Susanna Santagni, Jessica Daolio, Karen Gibbins, Francesco Antonino Battaglia, Giovanni Battista La Sala, Robert M Silver
PURPOSE: Low technology interventions for fertility enhancement (LTIFE) are strategies that avoid retrieval, handling, and manipulation of female gametes. The definition of LTIFE is yet to be widely accepted and clarified, but they are commonly used in milder cases of infertility and subfertility. Based on these considerations, the aim of the present study was comprehensively to review and investigate the obstetric and perinatal outcomes in subfertile patients who underwent LTIFE. METHODS: A literature search up to May 2017 was performed in IBSS, SocINDEX, Institute for Scientific Information, PubMed, Web of Science, and Google Scholar...
October 29, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29082422/antenatal-corticosteroids-administration-are-we-giving-them-at-the-right-time
#17
Tiffany Tuck Chin Wong, Janice Su Zhen Tung, Hester Chang Qi Lau, Shephali Tagore
OBJECTIVE: Antenatal corticosteroids before preterm births are considered to be most effective 48 h after and up to 1 week after the first dose. We aim to evaluate: (1) our practice of administration of antenatal corticosteroids in Singapore; (2) admission characteristics of women for discriminatory factors of spontaneous preterm delivery within 1 week. METHODS: This is a retrospective study in a tertiary obstetrics unit in Singapore. 3044 women who delivered live births (at term or preterm) from 1st November 2014 to 31st January 2015, who were at risk of spontaneous or induced preterm delivery, were included...
October 29, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29082421/does-ovarian-reserve-affect-outcomes-in-single-ideal-blastocyst-transfers-in-women-less-than-40%C3%A2-years-of-age
#18
Andrew Zakhari, Senem Ates, Talya Shaulov, Michael H Dahan
PURPOSE: There is much debate whether diminished ovarian reserve is purely a quantitative issue, or if quality as determined by pregnancy potential of the ensuing oocytes is also affected. The purpose of this study was to determine whether diminished ovarian reserve, as established by one of three ways described below, affects pregnancy outcomes of women under 40 years old undergoing a single ideal blastocyst transfer. MATERIALS AND METHODS: This was a retrospective cohort study, including 507 women undergoing an ideal quality single embryo transfer between August 2010 and March 2014...
October 29, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29080962/maternal-pre-pregnancy-obesity-and-the-risk-of-macrosomia-a-meta-analysis
#19
Rui-Xue Dai, Xiu-Jie He, Chuan-Lai Hu
PURPOSE: The aim of our meta-analysis was to explore whether pre-pregnancy obesity is regarded as an important risk factor for predicting macrosomia or not. METHODS: Three databases were systematically reviewed and reference lists of relevant articles were checked. Meta-analysis of published cohort studies comparing whether pre-pregnancy obesity was associated with macrosomia and adjusting for potential confounding factors. Calculations of pooled estimates were conducted in random-effect model...
October 28, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29075851/prehabilitation-in-gynecological-surgery-what-do-gynecologists-know-and-need-to-know
#20
Florian Ebner, Sebastian Viktor Waldemar Schulz, Amelie de Gregorio, Sophia Volz, Jürgen Michael Steinacker, Wolfgang Janni, Stephanie Otto
BACKGROUND/AIMS: The self-quantification of patients is extending beyond the daily routine. More and more patients ask about the 'optimal' physical condition for an elective surgery. As the hysterectomy is one of the most common surgeries, a literature review was conducted to answer the question for the optimal surgical self preparation (prehabilitation). METHODS: A literature review with the search terms 'physical activity' or 'physical exercise' or 'sport' or 'prehabilitation' and 'hysterectomy' was conducted in the National Library of Medicine database (PubMed) and Web of science...
October 26, 2017: Archives of Gynecology and Obstetrics
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