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Archives of Gynecology and Obstetrics

Jens Krugmann, Corinna Lang Schwarz, Balint Melcher, William Sterlacci, Agne Ozalinskaite, Johannes Lermann, Abbas Agaimy, Michael Vieth
BACKGROUND: Malignant ascites often develops in patients with ovarian cancer, but there is a lack of more detailed characterization of the different histological subtypes. METHODS: Ascites specimens from patients with ovarian cancer who were treated at Bayreuth Hospital from 2006 to 2015, with follow-up until December 2016, were reevaluated retrospectively. RESULTS: A total of 191 women (mean age 64 years, range 48-79) were included, of whom 180 (94...
November 10, 2018: Archives of Gynecology and Obstetrics
Yue He, Hui Zhao, Xing-Ming Li, Cheng-Hong Yin, Yu-Mei Wu
OBJECTIVE: The aim of this retrospective observational study was to analyze the clinical and pathological characteristics of small-cell neuroendocrine carcinoma of the gynecologic tract (SCNCGT). METHODS: Twenty patients with SCNCGT were enrolled and their clinic-pathological features were analyzed. All patients were treated at the Beijing Obstetrics and Gynecology Hospital, Capital Medical University, China, and were followed up until December 31, 2017. RESULTS: (1) Patient characteristics: The incidence of SCNCGT was 0...
November 8, 2018: Archives of Gynecology and Obstetrics
Tanja Nadine Stueber, Claire Rachel Weiss, Achim Woeckel, Sebastian Haeusler
BACKGROUND: To examine influences on the receptor status of a local cohort of patients with recurrent breast cancer after primary diagnosis of hormone receptor positive breast cancer. METHODS: We retrospectively analyzed 2078 female patients with primary hormone receptor positive breast cancer treated at the university hospital of Wuerzburg between 2000 and 2013. Main focus was on discordance in receptor status in recurrent disease. RESULTS: 196 patients with the primary diagnosis of hormone receptor positive breast cancer developed recurrent disease...
November 8, 2018: Archives of Gynecology and Obstetrics
Huiyan Hu, Jingjing Zhao, Wen Yu, Junwei Zhao, Zhewei Wang, Lin Jin, Yunyun Yu, Lingfei Han, Lu Wang, Huiting Zhu, Fang Li
OBJECTIVES: Cervical cancer is the most common malignant tumors in women leading to serious morbidity and mortality worldwide, especially among developing countries. A main cause of the disease is the high-risk human papillomavirus (HR-HPV) infection. HSIL usually progress to cervical cancer, and low-grade lesions, including LSIL and ASCUS, mostly turn to normal or benign lesions, but there are still a small number of patients who will progress to HSIL. Up to now there is no efficient biomarker clinically available to predict people with high risk to progress into HSIL...
November 2, 2018: Archives of Gynecology and Obstetrics
Sebastian Mayer, Severine Iborra, Donata Grimm, Lisa Steinsiek, Sven Mahner, Michaela Bossart, Linn Woelber, Pit Jacob Voss, Gerald Gitsch, Annette Hasenburg
OBJECTIVE: Sexual activity (SA) and functioning (SF) are important factors influencing quality of life (QoL). Anticancer treatment can cause or promote sexual dysfunctions. In this study we analyzed the SA, SF and QoL in patients after completion of treatment for breast cancer (BC) and ovarian cancer (OC). METHODS: In this retrospective multicenter study 396 BC patients and 93 OC patients aged between 18 and 70 years were surveyed at least 24 months after cancer diagnosis and compared to 60 healthy women...
November 1, 2018: Archives of Gynecology and Obstetrics
Jung Min Ryu, Yoon Seok Choi, Jin Young Bae
PURPOSE: The purpose of this study was to evaluate the effectiveness of intrauterine continuous running suture during cesarean section in pregnant women with placenta previa. METHODS: We enrolled 277 women and medical records were retrospectively reviewed. Pregnant women were grouped according to uterine bleeding control methods as follows: Group A, using intrauterine continuous running suture and Group B (control group) using figure-of-eight suture. RESULTS: Intrauterine continuous running sutures were used in 104 pregnant women...
November 1, 2018: Archives of Gynecology and Obstetrics
Thomas Kolben, Daniel Fischer, Ina Ruehl, Marie Franz, Anna Hester, Theresa Maria Kolben, Charlotte Deppe, Maria Delius, Klaus Friese, Sven Mahner, Uwe Hasbargen, Christoph Hübener
OBJECTIVE: To evaluate delayed interval deliveries in multiple gestations in regard of delayed interval and neonatal survival and to provide a protocol. METHODS: Data of multiple pregnancies with delayed interval delivery at a tertiary maternity unit between 2002 and 2017 were collected. Contraindications for evaluation of a delay of the delivery of the remaining child were: severe maternal blood loss, poor maternal general condition, preeclampsia, placental abruption, fetal distress, serious congenital malformations of the remaining child, chorioamnionitis, and premature rupture of membranes of the second fetus...
November 1, 2018: Archives of Gynecology and Obstetrics
Netanella Miller, Michel Pelleg, Nasrean Hag-Yahia, Yair Daykan, Yael Pasternak, Tal Biron-Shental
PURPOSE: Normal labor curves have not been assessed for women undergoing a trial of labor after cesarean delivery (TOLAC). This study examined labor patterns during TOLAC in relation to epidural analgesia use. METHODS: Retrospective cohort study of deliveries of women undergoing TOLAC at a single, academic, tertiary medical center. Length of first, second and third stages of labor was compared between 424 women undergoing TOLAC in the current labor with no previous vaginal delivery (VD) and 357 women with at least one previous VD and current TOLAC...
November 1, 2018: Archives of Gynecology and Obstetrics
Sarah Schott, Judith Heinzler, Nathalie Rippinger, Thomas Bruckner, Janina Brucker, Janine Hoffmann, Nadja Dornhöfer, Christine Dinkic, Stephan Seitz, Joachim Rom, Christof Sohn, Timm C Schott
BACKGROUND: Dental and cervical controls are two established screening programs in Germany. Compliance to orthodontic treatment in childhood is essential for dental health and one of the first health interventions that requires adherent behavior; therefore, it may be associated with participation in further screening programs in adulthood. However, it is not yet known whether early orthodontic treatment influences long-term screening adherence. METHODS: Using a questionnaire administered during a visit to a special dysplasia outpatient service, this case-control study evaluated women's personal history of orthodontic care, long-term satisfaction, and dental and gynecological screening adherence...
October 30, 2018: Archives of Gynecology and Obstetrics
Barbara Schmalfeldt, Christine Brambs, Alexander Burges, Ahmed El-Balat, Günter Emons, Daniel Fink, Christina Fotopoulou, Martina Gropp-Meier, Lars-Christian Hanker, Philipp Harter, Annette Hasenburg, Steffen Hauptmann, Felix Hilpert, Rainer Kimmig, Stefan Kommoss, Christian Kurzeder, Sven Mahner, Frederik Marmé, Doris Mayr, Werner Meier, Ivo Meinhold-Heerlein, Alexander Mustea, Olaf Ortmann, Gülten Oskay-Özcelik, Jacobus Pfisterer, Martin Pölcher, Ingo B Runnebaum, Willibald Schröder, Berno Tanner, Uwe Wagner, Pauline Wimberger, Jalid Sehouli
No abstract text is available yet for this article.
October 29, 2018: Archives of Gynecology and Obstetrics
Gaetano Valenti, Pietro Milone, Serena D'Amico, Lisa Maria Grazia Caldaci, Amerigo Vitagliano, Fabrizio Sapia, Michele Fichera
PURPOSE: Uterine fibroids (UFs) occur in 10% of pregnancies and may lead to severe maternal-fetal complications, mainly depending on UFs characteristics and the distance to the uterine cavity (UC). When symptomatic, UFs are managed medically. Nevertheless, in about 2% of cases, surgery becomes necessary. Entry into the UC should be avoided during myomectomy. Consequentially, pre-operative assessment of this risk could be beneficial. Ultrasonography (US) represents the gold standard for UFs assessment; however, scarce evidence has been produced to assess the role of magnetic resonance imaging (MRI)...
October 29, 2018: Archives of Gynecology and Obstetrics
Bernd Froessler, Tijana Gajic, Gustaaf Dekker, Nicolette A Hodyl
No abstract text is available yet for this article.
October 29, 2018: Archives of Gynecology and Obstetrics
Markus Schmidt, Maria Neophytou, Olaf Hars, Julia Freudenberg, Maritta Kühnert
PURPOSE: To provide real-world evidence using misoprostol vaginal insert (MVI) for induction of labor in nulliparous and parous women at two German Level I Centers in a prospective observational study. METHODS: Between 1 August 2014 and 1 October 2015, eligible pregnant women (≥ 36 + 0 weeks of gestation) requiring labor induction were treated with MVI. Endpoints included time to and mode of delivery rates of tocolysis use, tachysystole, uterine hypertonus or uterine hyperstimulation syndrome and newborn outcomes...
October 29, 2018: Archives of Gynecology and Obstetrics
Frederik A Stuebs, Carla E Schulmeyer, Grit Mehlhorn, Paul Gass, Sven Kehl, Simone K Renner, Stefan P Renner, Carol Geppert, Werner Adler, Arndt Hartmann, Matthias W Beckmann, Martin C Koch
PURPOSE: Colposcopy-directed biopsy is a cornerstone method for diagnosing cervical intraepithelial neoplasia. The aim of this study was to evaluate the accuracy of colposcopy-directed biopsy in comparison with definitive surgery. METHODS: The accuracy of colposcopy-directed biopsy was compared with the final histology in relation to different types of transformation zone (TZ), the patient's age, and the examiner's level of training. RESULTS: The overall accuracy of biopsy in comparison with definitive surgery was 71...
October 27, 2018: Archives of Gynecology and Obstetrics
Thomas Papathemelis, Sophia Scharl, Matthias Hipp, Anton Scharl, Matthias W Beckmann, Michael P Lux, Oliver Kölbl
PURPOSE: Vaginal brachytherapy reduces the risk of local recurrence and was shown to be equieffective in preventing vaginal vault recurrence, but less toxic compared to external-beam radiotherapy in a subset of high intermediate-risk endometrial cancer patients and is administered as single adjuvant treatment in those patients. Different radiotherapeutic approaches with various dosing schemes exist toward brachytherapy. The aim of this study was to compare the outcome and long-term quality of life after brachytherapy with two different high-dose-rate dosing schemes...
October 24, 2018: Archives of Gynecology and Obstetrics
Anne-Sophie Heimes, Marcus Schmidt, Joerg Jäkel, Katrin Almstedt, Susanne Gebhard, Veronika Weyer-Eiberich, Tania Elger, Slavomir Krajnak, Walburgis Brenner, Annette Hasenburg, Marco Johannes Battista
BACKGROUND: Tumor-infiltrating lymphocytes influence the prognosis of solid tumors, including ovarian cancer (OC). The immunoregulatory transcription factor (IRF4) is mainly expressed in plasma cells and regulates immunoglobulin class switch recombination as well as plasma cell differentiation. Therefore, we analyzed the impact of IRF4 expression in a consecutive cohort of OC patients. METHODS: IRF4 expression was evaluated by immunostaining. Differences in IRF4 expression among the subgroups of the established clinical-pathological features like age, histological subtype, tumor stage, histological grading, postoperative tumor burden, and completeness of chemotherapy were determined by χ2 test...
October 24, 2018: Archives of Gynecology and Obstetrics
Sophie Pils, Natalia Stepien, Christine Kurz, Kazem Nouri, Stephanie Springer, Marlene Hager, Regina Promberger, Johannes Ott
PURPOSE: To evaluate whether anti-Mullerian hormone, basal follicle-stimulating hormone, luteinizing hormone, estradiol, and female age would predict future outcomes in women with idiopathic recurrent miscarriage. METHODS: One hundred and sixteen women with idiopathic recurrent miscarriage were retrospectively included. Luteal support with or without a combined treatment regimen for idiopathic recurrent miscarriage was applied in a tertiary-care center in Vienna...
October 24, 2018: Archives of Gynecology and Obstetrics
Hironori Takahashi, Yosuke Baba, Rie Usui, Hirotada Suzuki, Kenji Horie, Hitoshi Yano, Akihide Ohkuchi, Shigeki Matsubara
AIMS: The aims of this study were to clarify: (i) the effectiveness of Matsubara-Yano uterine compression suture (MY) to achieve hemostasis in the presence of postpartum hemorrhage (PPH) during cesarean section, (ii) the type of PPH for which MY is effective, (iii) post-operative complications of MY, and (iv) outcomes of pregnancy after MY. METHODS: This retrospective observational study was performed using medical records of patients for whom MY had been performed between January 1, 2009 and December 31, 2017...
October 24, 2018: Archives of Gynecology and Obstetrics
Ibrahim A Abdelazim, Bassam Nusair, Shikanova Svetlana, Gulmira Zhurabekova
BACKGROUND: Iron deficiency (ID) and iron deficiency anemia (IDA) in pregnancy are global health issues, affecting around 30% of women in high-resourced countries, and increasing to over 50% of women in low-resourced countries. OBJECTIVES: Froessler et al. study published in Archives of Gynecology and Obstetrics (2018) 298: 75. , raised many queries and we would like to know the answers of those queries from the authors if possible...
October 22, 2018: Archives of Gynecology and Obstetrics
Xiao-Hui Jiang, Zou-Ying Yao, Xu He, Jian-Bo Zhang, Ke Xie, Jie Chen, Mei Cao, Jian Zhang, Shang-Mian Yie
PURPOSE: To examine the clinical significance of an autoantibody (AAb) against a novel tumor-associated antigen (TAA) derived from human DNA-topoisomerase I, termed as TOPO48 AAb, and peripheral blood survivin-expressing circulating cells (CCC) in patients with early stage endometrial cancer (EC). METHODS: Blood samples were collected from 80 patients with early stage EC and 80 age-matched healthy subjects. Plasma levels of the TOPO48 AAb were measured with a specific antibody capture enzyme-linked immunosorbent assay (ELISA) and blood survivin-expressing CCC assessed with a reverse transcription-polymerase chain reaction products based on a hybridization-enzyme-linked immunosorbent assay (RT-PCR-ELISA)...
October 19, 2018: Archives of Gynecology and Obstetrics
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