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Research in Developmental Disabilities

Peter Mazonson, Mark Kane, Kelin Colberg, Heather Harris, Heather Brown, Andrew Mohr, Chris Santas, Adrian Sandler
BACKGROUND: Although cord blood (CB) stem cell research is being conducted for treatment of cerebral palsy (CP), little is known about children with CP and stored CB. AIMS: To compare demographic and clinical characteristics of children with CP and stored CB to children with CP identified in a population-based study. METHODS AND PROCEDURES: The Longitudinal Umbilical Stem cell monitoring and Treatment REsearch (LUSTRE®) Registry recruited children from the largest US private CB bank...
July 12, 2018: Research in Developmental Disabilities
Gary N Siperstein, Avery B Albert, Holly E Jacobs, Karen J Osborne, Jeffrey E Stokes
BACKGROUND AND AIMS: The use of the word retard ("the r-word") among adolescents sheds light on societal views about individuals with intellectual disability and the need to address the colloquial use of this word and its underlying stigma. Schools provide an important platform for intervening to promote social change among youth. The present study examined the impact of a schoolwide social inclusion program on students' bystander behavior against the use of the r-word. METHODS AND PROCEDURES: 1233 students from 5 high schools were surveyed about the prevalence of the r-word in their school, the contexts in which it is used, and their bystander behavior in response to the word...
July 9, 2018: Research in Developmental Disabilities
Leigh Ann Tipton-Fisler, Geovanna Rodriguez, Sasha M Zeedyk, Jan Blacher
BACKGROUND: It is known that children with disabilities, especially adolescents with autism spectrum disorder (ASD), are at increased risk for victimization. However, little is known about the impact of victimization over time. AIMS: Primary aims included identifying to what extent risk factors (i.e., internalizing behavior problems and conflict in friendship) related to bullying victimization over time. METHODS AND PROCEDURES: In-depth interviews conducted separately with 15-year-olds with autism spectrum disorder (ASD), intellectual disability (ID), or typical development (TD) and their mothers investigated the experiences of victimization in a two-year follow up to an earlier study at adolescent age 13...
July 9, 2018: Research in Developmental Disabilities
Ka-Yan Leung, Henry Ho-Lung Chan, Mei-Po Leung
AIMS: This pilot study investigated perceptual and electrophysiological characteristics of dyslexic children, and evaluated the immediate and prolonged effect of visual perceptual training on these characteristics in these children. METHODS AND PROCEDURES: Seven dyslexic children and seven controls aged 7-8 years were recruited and completed this study. All dyslexic children completed 10-weeks of visual perceptual training. The visual perceptual skills were assessed and binocular visual evoked potentials (VEP) were recorded with two different pattern stimulations initially (Baseline), 3 months after the first assessment (Evaluation I) and 6 months after first assessment (Evaluation II)...
July 6, 2018: Research in Developmental Disabilities
Jo Van Herwegen, Maria Ashworth, Olympia Palikara
BACKGROUND: The current study examined parents' views about their child's educational provision for children with Williams syndrome (WS), Down syndrome (DS), and Autism Spectrum Disorders (ASD). AIMS: This cross-syndrome comparison explored the specific and general difficulties that parents of children with neurodevelopmental disorders experience about their child's educational provision. METHODS AND PROCEDURES: Parents of children aged 4-18;11 years old, including 99 with WS, 88 with DS, and 82 with ASD completed a survey...
July 5, 2018: Research in Developmental Disabilities
Utsana Tonmukayakul, Sophy T F Shih, Helen Bourke-Taylor, Christine Imms, Dinah Reddihough, Liz Cox, Rob Carter
BACKGROUND: Cerebral palsy (CP) and its associated conditions can pose a significant economic burden on families, the health care system and the general economy. The boundary for inclusion of costs in research can vary substantially across studies. AIMS: To summarize the evidence for burden of disease for CP including the impacts on the health system, the community and carers. METHODS: Literature was identified from Ovid Medline, Embase, CINHAL, PsyInfo, Econlit, Health Economic Evaluation Database (HEED) and NHS Economic Evaluation Database (NHS EED) in the Cochrane Library...
June 28, 2018: Research in Developmental Disabilities
Kimberly J Vannest, Corey Peltier, April Haas
Single Case Experimental Design is a discipline grounded in applied behavior analysis where the needs of individual clients and the application of scientific inquiry are fundamental tenets. These two principles remain tantamount in the conduct of research using this methodology and the expansion of the method into evidence-based practice determinations. Although recommendations for quality indicators are widespread, implementation is not. Concurrent to the rise of quality indicators is an increasing interest in analysis methodology...
June 27, 2018: Research in Developmental Disabilities
Rory O'Sullivan, Frances Horgan, Tim O'Brien, Helen French
AIM: To systematically review the natural history of crouch gait in bilateral cerebral palsy (CP) in the absence of surgical intervention and to review any relationship between clinical variables and progression of knee crouch. METHODS: Relevant literature was identified by searching article databases (PubMed, CINAHL, EMBASE, and Web of Science). Included studies reported on participants with bilateral CP who had 3-dimensional gait analysis on at least two occasions with no surgical interventions between analyses...
June 26, 2018: Research in Developmental Disabilities
Brian Reichow, Erin E Barton, Daniel M Maggin
Systematic reviews and meta-analyses can be a useful method for synthesizing evidence across multiple studies to draw conclusions about a research base. An important aspect of rigorous systematic reviews is an assessment of the study methods and potential biases impacting results or interpretations and conclusions of the primary studies. Single-case design (SCD) research has been a primary mechanism for identifying evidence-based practices across disciplines, but primarily in behavioral fields and special education...
June 26, 2018: Research in Developmental Disabilities
Milena Milićević, Goran Nedović
BACKGROUND: Children with cerebral palsy (CP) are at increased risk of reduced participation. Parental evaluation of child's participation is often the decision-making factor in the process of special education and/or rehabilitation. AIMS: Examine and compare home and community participation of children with CP and typical development (TD) and the associations between their parents' desire for change and participation dimensions in both settings. METHODS AND PROCEDURES: This cross-sectional study included a convenience sample of 110 children with CP (55% males; mean age 12...
June 26, 2018: Research in Developmental Disabilities
Swati M Surkar, Rashelle M Hoffman, Brenda Davies, Regina Harbourne, Max J Kurz
BACKGROUND: Action-planning and execution deficits in children with hemiplegic cerebral palsy (HCP) are potentially due to deficits in the integration of sensory information, such as vision, with motor output. AIMS: To determine differences in anticipatory visual patterns in children with HCP compared to typically developing (TD) children, and to assess visuomotor coordination in children with HCP. METHODS AND PROCEDURES: We included 13 children with HCP (Age = 6...
June 22, 2018: Research in Developmental Disabilities
Jennifer B Ganz
No abstract text is available yet for this article.
June 21, 2018: Research in Developmental Disabilities
Ellen Van Den Heuvel, Evi Jonkers, Ellen Rombouts, Eric Manders, Inge Zink, Ann Swillen
BACKGROUND: Development of cognitive skills and social responsiveness are areas of concern in children with 22q11.2 deletion syndrome (22q11DS). It remains unclear if the cognitive and social profiles and trajectories are syndrome-specific or similar to those of children with idiopathic intellectual disabilities (IID) with or without comorbid autism spectrum disorder (ASD). AIMS AND METHODS: In this exploratory study, we examined and compared five broad cognitive abilities (BCAs) and the social responsiveness in primary school-aged children with 22q11DS (age 6-13, n = 21) and IQ-matched peers with IID (n = 21)...
June 20, 2018: Research in Developmental Disabilities
Stephen R Hooper, Deborah Hatton, John Sideris, Kelly Sullivan, Peter A Ornstein, Donald B Bailey
BACKGROUND: Executive functions (EF) have been identified as impaired in FXS, but few studies have examined their developmental trajectories. AIMS: The primary aim of this longitudinal study was to examine the development of EF in young males with FXS compared to Mental Age (MA)-matched controls. METHODS AND PROCEDURES: The sample comprised 56 boys with FXS (ages 7-13 years), and 48 MA-matched typical boys (ages 4-8 years). EF tasks included measures of inhibitory control, working memory, cognitive flexibility/set-shifting, problem solving/planning, and processing speed...
June 20, 2018: Research in Developmental Disabilities
Dario Maglione, Marcella Caputi, Benedetta Moretti, Simona Scaini
BACKGROUND: In the last years, several studies focused on the role of Gene-Environment interactions (GxE) in influencing psychopathological outcomes among maltreated children and adolescents. These studies analysed the effect of different genetic variations. AIMS: The aim of the present review is to provide an overview of studies investigating GxE effects among maltreated children and adolescents. METHODS AND PROCEDURES: A systematic literature review was performed by using the following keywords: "Child maltreatment" and "GxE", "Child maltreatment" and "Psychopathology", "Gene-Environment interaction", "Gene-environment correlation", "GxE and psychopathology", "Childhood trauma" and "Psychiatric symptoms", "Early adverse life events", "Early life stress", "Antisocial behaviour", "Depression", "Internalizing symptoms", through the following electronic databases: PubMed, Scopus and PsycINFO, from 2006 to 2017, finding a total of 31 papers...
June 20, 2018: Research in Developmental Disabilities
Kemi E Wright, Bonnie J Furzer, Melissa K Licari, Ashleigh L Thornton, James A Dimmock, Louise H Naylor, Siobhan L Reid, Stephanie R Kwan, Ben Jackson
Children with low movement proficiency have been identified as having poorer physiological and psychosocial outcomes; however, the varied measurement approaches used to assess these outcomes have varied resulting in conflicting evidence regarding the presence and magnitude of differences compared to Typically Developing (TD) children. Additionally, there has been limited research into the role of parental support for physical activity (PA) in this group. We compared children with varying levels of movement proficiency on physiological characteristics and self-perceptions regarding PA...
June 16, 2018: Research in Developmental Disabilities
Pamela Heaton, Wai Fung Tsang, Kelly Jakubowski, Daniel Mullensiefen, Rory Allen
Deficits in auditory short-term memory have been widely reported in children with Specific Language Impairment (SLI), and recent evidence suggests that children with Autism Spectrum Disorder and co-morbid language impairment (ALI) experience similar difficulties. Music, like language relies on auditory memory and the aim of the study was to extend work investigating the impact of auditory short-term memory impairments to musical perception in children with neurodevelopmental disorders. Groups of children with SLI and ALI were matched on chronological age (CA), receptive vocabulary, non-verbal intelligence and digit span, and compared with CA matched typically developing (TD) controls, on tests of pitch and temporal acuity within a voluntary musical imagery paradigm...
June 15, 2018: Research in Developmental Disabilities
Anke M Klein, Esther O Houtkamp, Elske Salemink, Jeanine M D Baartmans, Mike Rinck, Mariët J van der Molen
BACKGROUND: Social anxiety and depressive symptoms are relatively common in adolescents with Mild to Borderline Intellectual Disabilities (MBID). Unfortunately, there are only a few studies that focus on examining processes underlying social anxiety and depression in these adolescents. AIMS: The aim was to examine the differences between self- and peer-rated likability in relation to social anxiety and depression in the classroom environment. METHODS AND PROCEDURES: 631 normative non-clinical adolescents with MBID completed questionnaires to measure social anxiety, depression, and the estimation of their own likability by peers...
June 13, 2018: Research in Developmental Disabilities
Heather C Karras, Danita N Morin, Kamaldeep Gill, Sara Izadi-Najafabadi, Jill G Zwicker
BACKGROUND: Although Developmental Coordination Disorder (DCD) is primarily a motor disorder, it can also impact emotional and psychosocial functioning of children with this condition. Evidence suggests that children with DCD experience lower quality of life than their peers, but few studies have explicitly examined the health-related quality of life (HRQOL) of these children. AIMS: To: (1) describe HRQOL of children with DCD compared to typically-developing children; (2) compare HRQOL from the perspectives of children with DCD and their parents; and (3) explore predictors of HRQOL for children with DCD...
June 12, 2018: Research in Developmental Disabilities
Ayelet Harel-Gadassi, Edwa Friedlander, Maya Yaari, Benjamin Bar-Oz, Smadar Eventov-Friedman, David Mankuta, Nurit Yirmiya
The aim of this study is to examine the effect of age correction on the developmental assessment scores of preterm infants, using for the first time, the Mullen scales of early learning (MSEL) test. Participants included 110 preterm infants (born at a gestational age of ≤ 34 weeks) at ages 1, 4, 8, 12, 18, 24 and 36 months. The corrected age-based MSEL composite score and each of the five MSEL scale scores were significantly higher than chronological age-based scores at all ages. These corrected scores were significantly higher than the chronological scores regardless of gestational age whether weight was, or adequate or small for gestational age...
June 12, 2018: Research in Developmental Disabilities
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