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Obstetrics and Gynecology Clinics of North America

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https://www.readbyqxmd.com/read/29747739/medical-disorders-in-pregnancy
#1
EDITORIAL
Erika Peterson, Judith U Hibbard
No abstract text is available yet for this article.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747738/team-based-care-of-pregnant-women-with-challenging-medical-disorders
#2
EDITORIAL
William F Rayburn
No abstract text is available yet for this article.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747737/thromboprophylaxis-in-pregnancy
#3
REVIEW
Diana Kolettis, Sabrina Craigo
Venous thromboembolism is a leading cause of maternal morbidity and mortality worldwide. Identifying women who are at greatest risk for venous thromboembolism, and managing their pregnancies with appropriate thromboprophylaxis is essential to decreasing this life-threatening condition. Those at greatest risk are patients with thrombophilias, a personal or family history of venous thromboembolism, and those undergoing cesarean delivery. Current international guidelines on thromboprophylaxis vary in details, but all strategies rely on risk factor identification and thromboprophylaxis for the highest risk patients...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747736/infections-in-pregnancy-and-the-role-of-vaccines
#4
REVIEW
Kimberly B Fortner, Claudia Nieuwoudt, Callie F Reeder, Geeta K Swamy
Pregnant women are at risk for infection and may have significant morbidity or mortality. Influenza, pertussis, zika, and cytomegalovirus produce mild or asymptomatic illness in the mother, but have profound implications for her fetus. Maternal immunization can prevent or mitigate infections in pregnant women and their infants. The Advisory Committee of Immunization Practices recommends 2 vaccines during pregnancy: inactivated influenza, and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis during pregnancy...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747735/seizures-in-pregnancy
#5
REVIEW
Kassie J Bollig, Daniel L Jackson
Seizures are among the most serious neurologic complications encountered in pregnancy. This review provides a foundation for the initial diagnosis, evaluation, classification, and management of seizures during pregnancy.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747734/hypertensive-disorders-in-pregnancy
#6
REVIEW
Amelia L M Sutton, Lorie M Harper, Alan T N Tita
Hypertensive disorders of pregnancy are a heterogeneous group of conditions that include chronic hypertension, gestational hypertension, preeclampsia, and preeclampsia superimposed on chronic hypertension. These disorders account for a significant proportion of perinatal morbidity and mortality nearly 10% of all maternal deaths in the United States. Given the substantial health burden of hypertensive disorders in pregnancy, there is increasing interest in optimizing management of these conditions. This article summarizes the diagnosis and management of each of the disorders in the spectrum of hypertension in pregnancy and highlights recent updates in the field...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747733/pregestational-diabetes-in-pregnancy
#7
REVIEW
Ronan Sugrue, Chloe Zera
Diabetes is a common chronic condition in women of reproductive age. Preconception care is crucial to reducing the risk of adverse maternal and fetal outcomes, such as hypertensive disorders, abnormal fetal growth, traumatic delivery and stillbirth, associated with poor glycemic control. Insulin is the preferred medication to optimize glucose control in women with pregestational diabetes. Frequent dose adjustments are needed during pregnancy to achieve glycemic goals, and team-based multidisciplinary care may help...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747732/gestational-diabetes-underpinning-principles-surveillance-and-management
#8
REVIEW
Jeffrey M Denney, Kristen H Quinn
Gestational diabetes mellitus (GDM) is carbohydrate intolerance resulting in hyperglycemia with onset during pregnancy. The article aims to provide clinicians with a working framework to minimize maternal and neonatal morbidity. Landmark historical and recent data are reviewed and presented to provide clinicians with a quick, easy reference for recognition and management of GDM. Data presented tie in insights with underlying pathophysiologic processes leading to GDM. Screening and diagnostic thresholds are discussed along with management upon diagnosis...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747731/new-insights-in-peripartum-cardiomyopathy
#9
REVIEW
Meredith O Cruz, Joan Briller, Judith U Hibbard
Significant progress in understanding the pathophysiology of peripartum cardiomyopathy, especially hormonal and genetic mechanisms, has been made. Specific criteria should be used for diagnosis, but the disease remains a diagnosis of exclusion. Both long-term and recurrent pregnancy prognoses depend on recovery of cardiac function. Data from large registries and randomized controlled trials of evidence-based therapeutics hold promise for future improved clinical outcomes.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747730/maternal-congenital-heart-disease-in-pregnancy
#10
REVIEW
Megan E Foeller, Timothy M Foeller, Maurice Druzin
Congenital heart disease comprises most maternal cardiac diseases in pregnancy and is an important cause of maternal, fetal, and neonatal morbidity and mortality worldwide. Pregnancy is often considered a high-risk state for individuals with structural heart disease as a consequence of a limited ability to adapt to the major hemodynamic changes associated with pregnancy. Preconception counseling and evaluation are of utmost importance, as pregnancy is contraindicated in certain cardiac conditions. Pregnancy can be safely accomplished in most individuals with careful risk assessment before conception and multidisciplinary care throughout pregnancy and the postpartum period...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747729/maternal-genetic-disorders-in-pregnancy
#11
REVIEW
Sarah Harris, Neeta L Vora
The life expectancy and quality of life of women with genetic disorders continues to improve, resulting in more women reaching reproductive age and desiring fertility. It is becoming increasingly important that obstetricians become familiar with common genetic disorders and their associated risks in pregnancy. The authors review pregnancy in women with various genetic disorders, including review of pregnancy outcomes, management recommendations, and genetic risk assessment. Most data on pregnancies in women with genetic conditions are based on case reports and literature reviews...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747728/management-of-obstructive-sleep-apnea-in-pregnancy
#12
REVIEW
Jennifer E Dominguez, Linda Street, Judette Louis
The spectrum of sleep-disordered breathing (SDB) ranges from mild snoring to obstructive sleep apnea, the most severe form of SDB. Current recommendations are to treat these women with continuous positive airway pressure despite limited data. SDB in early and mid-pregnancy is associated with preeclampsia and gestational diabetes. Pregnant women with a diagnosis of obstructive sleep apnea at delivery were at significantly increased risk of having cardiomyopathy, congestive heart failure, pulmonary embolism, and in-hospital death...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747727/pregnancy-in-women-with-obesity
#13
REVIEW
Cara D Dolin, Michelle A Kominiarek
Pregnancy in women with obesity is an important public health problem with short- and long-term implications for maternal and child health. Obesity complicates almost all aspects of pregnancy. Given the growing prevalence of obesity in women, obstetric providers need to understand the risks associated with obesity in pregnancy and the unique aspects of management for women with obesity. Empathic and patient-centered care, along with knowledge, can optimize outcomes for women and children.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747726/opioid-use-disorders-and-pregnancy
#14
REVIEW
Amanda J Johnson, Cresta W Jones
Opioid use disorder presents an increased risk of complications in pregnancy, particularly when untreated. To optimize outcomes, medication-assisted treatment using methadone or buprenorphine as a part of a comprehensive care model is recommended. Neonatal abstinence syndrome and poor fetal growth remain significant complications of this disorder despite maternal treatment.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747725/cancer-in-pregnancy
#15
REVIEW
Anna McCormick, Erika Peterson
This article reviews some of the more common types of cancer that may be encountered during pregnancy. It reviews the unique challenges with the diagnosis and treatment of breast, cervical, hematologic, and colon cancers in pregnant patients.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747724/maternal-mortality-in-the-twenty-first-century
#16
REVIEW
John A Ozimek, Sarah J Kilpatrick
Maternal mortality plagues much of the world. There were 303,000 maternal deaths in 2015 representing an overall global maternal mortality ratio of 216 maternal deaths per 100,000 live births. In the United States, the maternal mortality ratio had been decreasing until 1987, remained stable until 1999, and then began to increase. Racial disparities exist in the rates of maternal mortality in the United States with maternal death affecting a higher proportion of black women compared with white women. To reduce maternal mortality, national organizations in the United States have called for standardized review of cases of maternal morbidity and mortality...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29428290/reproductive-genetics
#17
EDITORIAL
Lorraine Dugoff
No abstract text is available yet for this article.
March 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29428289/update-on-reproductive-genetics-what-an-obstetrician-gynecologist-needs-to-know
#18
EDITORIAL
William F Rayburn
No abstract text is available yet for this article.
March 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29428288/ethnicity-based-carrier-screening
#19
REVIEW
Jennifer R King, Susan Klugman
Ethnicity-based carrier screening for single-gene disorders is an integral part of preconception and prenatal care. The role of ethnicity-based carrier screening has expanded over time with advancing technology. Patients and providers should understand the benefits and limitations of their screening options and engage in appropriate pretest and posttest counseling. The future management of single-gene disorders is changing and a time may be approaching when ethnicity-based carrier screening will be replaced with expanded carrier screening...
March 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29428287/whole-exome-sequencing-applications-in-prenatal-genetics
#20
REVIEW
Angie C Jelin, Neeta Vora
Prenatal whole exome sequencing (WES) has the potential to increase the ability to provide more diagnostic capabilities in fetuses with sonographic abnormalities, which would then improve the ability to counsel families. It is also often the first step in improving the path toward informed diagnosis and treatment, which is especially important in the era of advancing in utero fetal therapy. This article discusses the current literature regarding prenatal WES, clinical indications for WES, challenges with interpretation/counseling (variants of unknown significance), research priorities, ethical issues, and potential future advances...
March 2018: Obstetrics and Gynecology Clinics of North America
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