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Hematology/oncology Clinics of North America

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https://www.readbyqxmd.com/read/29729790/pain-a-complex-challenge
#1
EDITORIAL
Janet L Abrahm
No abstract text is available yet for this article.
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729789/erratum
#2
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729788/pain-syndromes-and-management-in-adult-hematopoietic-stem-cell-transplantation
#3
REVIEW
Joseph D Ma, Areej R El-Jawahri, Thomas W LeBlanc, Eric J Roeland
Pain is a significant physical symptom that can be observed across the spectrum of hematopoietic stem cell transplant (HSCT) care. Pain assessment should include evaluation of the physical and functional components of pain. Management varies based on the type of HSCT-specific pain syndrome. Future directions for management of pain syndromes include the early integration of palliative care. The purpose of this review is to summarize various pain syndromes and management approaches in adult HSCT patients.
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729787/key-components-of-pain-management-for-children-and-adults-with-sickle-cell-disease
#4
REVIEW
Amanda M Brandow, Michael R DeBaun
Sickle cell disease pain manifests as severe acute pain episodes and a debilitating chronic pain syndrome. Acute pain episodes are the most common reason for health care use; however, acute pain episodes are also frequently managed at home. Chronic pain syndrome develops in 30% to 40% of individuals with sickle cell disease, with an increasing incidence and severity with age. We review the critical aspects of pain management that are integral to the comprehensive approach to sickle cell disease pain and are rooted in the biopsychosocial model...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729786/oncology-acupuncture-for-chronic-pain-in-cancer-survivors-a-reflection-on-the-american-society-of-clinical-oncology-chronic-pain-guideline
#5
REVIEW
Weidong Lu, David S Rosenthal
Chronic pain syndromes associated with cancer treatment are common but difficult to manage. The American Society of Clinical Oncology recently published a practice guideline to address the unmet needs of cancer survivors, Management of Chronic Pain in Survivors of Adult Cancers, which stresses the importance of implementing integrative therapies including acupuncture. This review focuses on randomized clinical trials of acupuncture for chronic pain in cancer survivors, including its use in chemotherapy-induced peripheral neuropathy, aromatase inhibitor-associated arthralgia, and post neck dissection pain, and provides future directions of oncology acupuncture research in cancer survivorship...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729785/spiritual-considerations
#6
REVIEW
Christina M Puchalski, Stephen D W King, Betty R Ferrell
Spiritual issues play a prominent role for patients with cancer. Studies have demonstrated a positive connection between a patient's spirituality and health outcomes, including quality of life, depression and anxiety, hopefulness, and the ability to cope with illness. Spiritual or existential distress is prominent in patients with cancer. Models are described that identify ways for clinicians to identify or diagnose spiritual or existential distress, and to attend to that distress. It is critical that all clinicians assess for spiritual distress as part of a routine distress assessment, identify appropriate treatment strategies, and work closely with trained spiritual care professionals...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729784/mindfulness-based-interventions-for-hematology-and-oncology-patients-with-pain
#7
REVIEW
Denise Hess
Pain is a reality for approximately half of all of patients with cancer and can negatively affect patient cognitive and emotional states, resulting in "total pain." Total pain may not respond to pharmacologic interventions and may pave the way for the onset of suffering, where suffering is defined as physical pain accompanied by negative cognitive interpretations. Mindfulness-based interventions provide an alternate interpretive framework for both pain and suffering and may lessen a patient's experience of pain...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729783/psychological-treatment
#8
REVIEW
Thomas B Strouse, Brenda Bursch
Psychological approaches to pain management have been demonstrated to be effective for individuals newly diagnosed with cancer, in remission, and/or with progressive or terminal disease. Modalities that have been demonstrated to be most effective are cognitive behavioral approaches that include relaxation skills and/or hypnotherapy.
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729782/rehabilitation-medicine-approaches-to-pain-management
#9
REVIEW
Andrea L Cheville, Sean R Smith, Jeffrey R Basford
Rehabilitation medicine offers strategies that reduce musculoskeletal pain, targeted approaches to alleviate movement-related pain, and interventions to optimize patients' function despite the persistence of pain. These approaches fall into four categories: modulating nociception, stabilizing and unloading painful structures, influencing pain perception, and alleviating soft tissue musculotendinous pain. Incorporating these interventions into individualized, comprehensive pain management programs offers the potential to empower patients and limit pain associated with mobility and required daily activities...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729781/radiation-for-treatment-of-painful-bone-metastases
#10
REVIEW
Ron Shiloh, Monica Krishnan
Several variables may be considered when deciding on optimal modality of radiation therapy for each cancer patient with bone pain, including prognosis, tumor histology, location and extent of metastases, and association with cord compression. Hypofractionated external beam radiation therapy is as effective as a multiple fraction radiotherapy course in most cases, although retreatment rates are higher after a single dose of radiation. Stereotactic body radiation may be used in cases of oligometastatic disease, repeat irradiation, and radiation-resistant tumors...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729780/mechanisms-of-and-adjuvants-for-bone-pain
#11
REVIEW
Nicholas Figura, Joshua Smith, Hsiang-Hsuan Michael Yu
Metastatic bone pain is a complex, poorly understood process. Understanding the unique mechanisms causing cancer-induced bone pain may lead to potential therapeutic targets. This article discusses the effects of osteoclast overstimulation within the tumor microenvironment; the role of inflammatory factors at the tumor-nociceptor interface; the development of structural instability, causing mechanical nerve damage; and, ultimately, the neuroplastic changes in the setting of sustained pain. Several adjuvant therapies are available to attenuate metastatic bone pain...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729779/interventional-anesthetic-methods-for-pain-in-hematology-oncology-patients
#12
REVIEW
Holly Careskey, Sanjeet Narang
This article reviews anesthetic interventional approaches to the management of pain in hematology and oncology patients. It includes a discussion of single interventions including peripheral nerve blocks, plexus injections, and sympathetic nerve neurolysis, and continuous infusion therapy through implantable devices, such as intrathecal pumps, epidural port-a-caths, and tunneled catheters. The primary objective is to inform members of hematology and oncology care teams regarding the variety of interventional options for patients with cancer-related pain for whom medical pain management methods have not been effective...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729778/cancer-related-neuropathic-pain-review-and-selective-topics
#13
REVIEW
Mellar P Davis
Neuropathic pain is the result of neuroplastic and neuroinflammatory changes from trauma or diseases that damage the somatosensory system. Cancer-related neuropathic pain is caused by treatment, cancer, or paraneoplastic reactions to cancer. Approximately 30% of patients with cancer have neuropathic pain, mostly mixed nociceptive and neuropathic pain. History, physical examination, quantitative sensory testing, skin punch biopsies, and functional MRIs help to divide pain into phenotypes that may facilitate analgesic choices...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729777/methadone-maximizing-safety-and-efficacy-for-pain-control-in-patients-with-cancer
#14
REVIEW
Mary Lynn McPherson, Ryan C Costantino, Alexandra L McPherson
Methadone is a valuable opioid in the management of patients who have cancer with pain. Methadone is a mu-, kappa-, and delta-opioid agonist, and an N-methyl-D-aspartate receptor antagonist. These mechanisms of action make methadone an attractive option for complex pain syndromes. It is critically important that providers consider a patient's risk status before beginning methadone. Careful consideration must be given to dosing methadone in both opioid-naïve and opioid-tolerant patients, with vigilant monitoring for therapeutic effectiveness and potential toxicity until the patient achieves steady state...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729776/safe-opioid-use-management-of-opioid-related-adverse-effects-and-aberrant-behaviors
#15
REVIEW
Joseph Arthur, David Hui
Opioids are highly effective for cancer pain but are associated with multiple adverse effects and risk of addiction. This article provides a synopsis on the management of various opioid-related adverse effects and strategies to minimize aberrant opioid use in patients who have cancer. Many adverse effects can be effectively managed. Some patients on chronic opioid therapy may demonstrate aberrant behaviors suggestive of opioid misuse or diversion. Through intensive education, longitudinal monitoring, early identification, and timely management, clinicians can optimize the risk to benefit ratio to support safe opioid use...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729775/cancer-pain-syndromes
#16
REVIEW
Russell K Portenoy, Ebtesam Ahmed
Patients with cancer experience many acute and chronic pain syndromes, the identification of which may be helpful in the assessment and treatment of pain. Syndromes are defined by the relationship with the cancer, the pain pathophysiology, and the clinical characteristics of the pain. The most common pain syndromes are directly related to the tumor; bone pain syndromes are most common. Neuropathic pain syndromes may involve cancer-related injury at any level of the peripheral nervous system. Treatment-related pain syndromes may follow any type of antineoplastic therapy...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729774/complex-cancer-pain-assessment
#17
REVIEW
Regina M Fink, Jeannine M Brant
Pain is widespread, multidimensional, and one of the most distressing symptoms patients with cancer face. Pain assessment is the foundation to optimal pain management. Despite evidence-based practice guidelines, inadequate pain assessment is a barrier. Patients should be routinely screened for pain at each encounter. If new, worsening, or persistent pain is present, a comprehensive pain assessment and reassessment should be regularly performed and documented to communicate the pain problem. Patient self-report of pain is the gold standard even in those who are nonverbal or cognitively impaired...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29458738/thalassemia
#18
EDITORIAL
Ali T Taher
No abstract text is available yet for this article.
April 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29458737/erratum
#19
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29458736/emerging-therapies
#20
REVIEW
Amaliris Guerra, Khaled M Musallam, Ali T Taher, Stefano Rivella
At present, the only definitive cure for β-thalassemia is a bone marrow transplant (BMT); however, HLA-blood-matched donors are scarcely available. Current therapies undergoing clinical investigation with most potential for therapeutic benefit are the β-globin gene transfer of patient-specific hematopoietic stem cells followed by autologous BMT. Other emerging therapies deliver exogenous regulators of several key modulators of erythropoiesis or iron homeostasis. This review focuses on current approaches for the treatment of hemoglobinopathies caused by disruptions of β-globin...
April 2018: Hematology/oncology Clinics of North America
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