journal
MENU ▼
Read by QxMD icon Read
search

Journal of Veterinary Internal Medicine

journal
https://www.readbyqxmd.com/read/28627123/pharmacokinetics-and-relative-bioavailability-of-orally-administered-innovator-formulated-itraconazole-capsules-and-solution-in-healthy-dogs
#1
A E Hasbach, D K Langlois, E J Rosser, M G Papich
BACKGROUND: Itraconazole is commonly used for treatment of systemic and cutaneous mycoses in veterinary medicine. Two formulations, capsule and solution, are used interchangeably in dogs. However, marked differences in bioavailability have been reported in other species. Similar investigations have not been performed in dogs. OBJECTIVE: To determine and compare pharmacokinetics of itraconazole in dogs after oral administration of commercially available capsule and solution formulations intended for use in humans...
June 19, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28626960/whole-blood-taurine-concentrations-in-cats-with-intestinal-disease
#2
A Kathrani, A J Fascetti, J A Larsen, C Maunder, E J Hall
BACKGROUND: Increased delivery of taurine-conjugated bile acids to the distal bowel can lead to dysbiosis resulting in colitis in mouse models of inflammatory bowel disease. A similar situation also could occur in cats with intestinal disease and might therefore result in decreased whole-body taurine concentration. HYPOTHESIS/OBJECTIVES: To determine whether whole-blood taurine concentrations are decreased at the time of diagnosis in cats with intestinal disease and to correlate concentrations with clinical and laboratory variables...
June 19, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28626958/letter-to-the-editor
#3
LETTER
P R Fox, M D Kittleson, C Basso, G Thiene
No abstract text is available yet for this article.
June 19, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28626919/letter-to-the-editor
#4
LETTER
T Ishikawa, N Makita, H Aoki, Y Saida
No abstract text is available yet for this article.
June 19, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28626891/evaluation-of-serum-3-bromotyrosine-concentrations-in-dogs-with-steroid-responsive-diarrhea-and-food-responsive-diarrhea
#5
P Sattasathuchana, K Allenspach, R Lopes, J S Suchodolski, J M Steiner
BACKGROUND: The clinical usefulness of serum 3-BrY concentrations for subclassifying dogs with food-responsive diarrhea (FRD) and steroid-responsive diarrhea (SRD) has not been studied. HYPOTHESIS/OBJECTIVES: To compare serum 3-BrY concentrations in dogs with FRD, dogs with SRD, and healthy control dogs. ANIMALS: 38 dogs with FRD, 14 dogs with SRD, and 46 healthy dogs. METHODS: Prospective study. Measurement of 3-BrY concentration in serum samples was performed by gas chromatography/mass spectrometry...
June 19, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28625019/efficacy-of-azithromycin-and-compounded-atovaquone-for-treatment-of-babesia-gibsoni-in-dogs
#6
S K Kirk, J K Levy, P C Crawford
BACKGROUND: Approximately one-third of dogs confiscated during dogfighting investigations are infected with Babesia gibsoni. Traditional management of B. gibsoni with polymerase chain reaction (PCR)-screening, treatment with commercially available azithromycin and atovaquone, and PCR testing after 60 and 90 days is costly and impractical for large numbers of dogs at a time. HYPOTHESIS/OBJECTIVES: To assess the efficacy of an alternative protocol in which commercial atovaquone was replaced by compounded medication and PCR monitoring was initiated at 30 days after the end of treatment to decrease the total management time...
June 17, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28617995/investigation-of-an-n-terminal-prohormone-of-brain-natriuretic-peptide-point-of-care-elisa-in-clinically-normal-cats-and-cats-with-cardiac-disease
#7
A N Harris, S S Beatty, A H Estrada, B Winter, M Bohannon, I Sosa, J Hanscom, C A Mainville, A E Gallagher
BACKGROUND: N-terminal prohormone of brain natriuretic peptide (NT-proBNP) concentrations may be increased in cats with various cardiac disorders. The point-of-care (POC) ELISA assay uses the same biologic reagents as the quantitative NT-proBNP ELISA. Previous studies have evaluated the sensitivity and specificity of the POC ELISA in cats with cardiac disease. OBJECTIVES: To prospectively evaluate the diagnostic utility of the POC ELISA in a select population of cats...
June 15, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28612380/breed-coat-color-and-hair-length-as-risk-factors-for-hyperthyroidism-in-cats
#8
V J Crossley, A Debnath, Y M Chang, R C Fowkes, J Elliott, H M Syme
BACKGROUND: Hyperthyroidism is very common in older cats, but the etiopathogenesis is poorly understood. Decreased risk of hyperthyroidism has been reported in certain colorpoint breeds, and this observation previously has been hypothesized to result from relatively greater tyrosine availability for thyroid hormone production because of limited ability to convert tyrosine to melanin pigment. However, studies investigating a potential link between coat pigmentation and risk of hyperthyroidism are limited...
June 13, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28608635/cardiac-and-metabolic-variables-in-obese-dogs
#9
M Tropf, O L Nelson, P M Lee, H Y Weng
BACKGROUND: The etiology of obesity-related cardiac dysfunction (ORCD) is linked to metabolic syndrome in people. Studies have indicated that obese dogs have components of metabolic syndrome, warranting evaluation for ORCD in obese dogs. OBJECTIVES: To evaluate cardiac structure and function and metabolic variables in obese dogs compared to ideal weight dogs. ANIMALS: Forty-six healthy, small-breed (<25 pounds), obese dogs (n = 29) compared to ideal weight dogs (n = 17)...
June 13, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28608577/use-of-a-granulocyte-immunofluorescence-assay-designed-for-humans-for-detection-of-antineutrophil-cytoplasmic-antibodies-in-dogs-with-chronic-enteropathies
#10
J Florey, A Viall, S Streu, V DiMuro, A Riddle, J Kirk, L Perazzotti, K Affeldt, R Wagner, S Vaden, T Harris, K Allenspach
BACKGROUND: Perinuclear antineutrophil cytoplasmic antibodies (pANCA) previously have been shown to be serum markers in dogs with chronic enteropathies, with dogs that have food-responsive disease (FRD) having higher frequencies of seropositivity than dogs with steroid-responsive disease (SRD). The indirect immunofluorescence (IIF) assay used in previous publications is time-consuming to perform, with low interobserver agreement. HYPOTHESIS/OBJECTIVES: We hypothesized that a commercially available granulocyte IIF assay designed for humans could be used to detect perinuclear antineutrophil cytoplasmic antibodies in dogs...
June 13, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28602021/evaluation-of-mollicutes-microorganisms-in-respiratory-disease-of-cattle-and-their-relationship-to-clinical-signs
#11
G Tortorelli, N Carrillo Gaeta, B L Mendonça Ribeiro, L Miranda Marques, J Timenetsky, L Gregory
BACKGROUND: Bovine respiratory disease (BRD) is an important problem in cattle production that is responsible for economic losses in dairy herds. Mycoplasma spp. are described as an important etiological agent of BRD. HYPOTHESIS: To evaluate the occurrence of the most important mycoplasmas in the lower respiratory tract of healthy and BRD cattle in relationship to clinical signs of BRD. ANIMALS: Sixty young dairy cattle were classified as healthy (n = 32) or cattle showing clinical signs of BRD (n = 28)...
June 10, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28573754/mitral-regurgitation-severity-and-left-ventricular-systolic-dimension-predict-survival-in-young-cavalier-king-charles-spaniels
#12
M J Reimann, J E Møller, J Häggström, T Martinussen, S S C Zatrazemi, L Svanholm, L B M Nielsen, H D Pedersen, L H Olsen
BACKGROUND: Development and progression of myxomatous mitral valve disease (MMVD) in dogs are difficult to predict. Identification at a young age of dogs at high risk of adverse outcome in the future is desirable. HYPOTHESIS/OBJECTIVES: To study the predictive value of selected clinical and echocardiographic characteristics associated with MMVD obtained at a young age for prediction of long-term cardiac and all-cause mortality in Cavalier King Charles Spaniels (CKCS)...
June 1, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28568169/effect-of-dexamethasone-and-fluticasone-on-airway-hyperresponsiveness-in-horses-with-inflammatory-airway-disease
#13
R Léguillette, T Tohver, S L Bond, J A Nicol, K J McDonald
BACKGROUND: Airway hyperresponsiveness (AWHR), expressed as hypersensitivity (PC75 RL ) or hyperreactivity (slope of the histamine dose-response curve), is a feature of inflammatory airway disease (IAD) or mild equine asthma in horses. Glucocorticoids are used empirically to treat IAD. OBJECTIVES: To determine whether dexamethasone (DEX) (0.05 mg/kg IM q24h) and inhaled fluticasone (FLUT) (3,000 μg q12h) administered by inhalation are effective in decreasing AWHR, lung inflammation, and clinical signs in horses with IAD...
May 31, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28561898/validation-of-a-point-of-care-quantitative-equine-igg-turbidimetric-immunoassay-and-comparison-of-igg-concentrations-measured-with-radial-immunodiffusion-and-a-point-of-care-igg-elisa
#14
S Ujvari, C C Schwarzwald, N Fouché, J Howard, A Schoster
BACKGROUND: Point-of-care (POC) diagnostic tests with good sensitivity and specificity are needed for diagnosing failure of transfer of passive immunity (FTPI) in foals. Turbidimetric immunoassays (TIA) have these characteristics and provide quantitative results. A commercially available TIA-based POC test (POC-TIA) has not been validated in horses. OBJECTIVE: To validate a POC-TIA and compare results of POC-TIA, a POC-ELISA, and radial immunodiffusion (RID). ANIMALS: Heparinized blood samples (n = 127) from 48 hospitalized foals (<12 hour to 48 days)...
May 31, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28558145/prevalence-of-vector-borne-pathogens-in-southern-california-dogs-with-clinical-and-laboratory-abnormalities-consistent-with-immune-mediated-disease
#15
L Kidd, B Qurollo, M Lappin, K Richter, J R Hart, S Hill, C Osmond, E B Breitschwerdt
BACKGROUND: Studies investigating the prevalence of vector-borne pathogens in southern California dogs are limited. Occult infections might be misdiagnosed as idiopathic immune-mediated disease. HYPOTHESIS/OBJECTIVES: (1) To determine the prevalence of vector-borne pathogens in southern California dogs with compatible clinical findings using PCR and serologic panels and (2) to determine whether testing convalescent samples and repeating PCR on acute samples using the same and different gene targets enhance detection...
May 30, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28557061/classification-of-involuntary-movements-in-dogs-myoclonus-and-myotonia
#16
REVIEW
M Lowrie, L Garosi
Myoclonus is a sudden brief, involuntary muscle jerk. Of all the movement disorders, myoclonus is the most difficult to encapsulate into any simple framework. On the one hand, a classification system is required that is clinically useful to aid in guiding diagnosis and treatment. On the other hand, there is need for a system that organizes current knowledge regarding biological mechanisms to guide scientific research. These 2 needs are distinct, making it challenging to develop a robust classification system suitable for all purposes...
May 30, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28557000/clinical-trials-in-veterinary-medicine-a-new-era-brings-new-challenges
#17
M A Oyama, S S Ellenberg, P A Shaw
Randomized clinical trials (RCTs) are among the most rigorous ways to determine the causal relationship between an intervention and important clinical outcome. Their use in veterinary medicine has become increasingly common, and as is often the case, with progress comes new challenges. Randomized clinical trials yield important answers, but results from these studies can be unhelpful or even misleading unless the study design and reporting are carried out with care. Herein, we offer some perspective on several emerging challenges associated with RCTs, including use of composite endpoints, the reporting of different forms of risk, analysis in the presence of missing data, and issues of reporting and safety assessment...
May 30, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28556535/mineral-composition-of-uroliths-obtained-from-sheep-and-goats-with-obstructive-urolithiasis
#18
M L Jones, P M Gibbons, A J Roussel, B J Dominguez
BACKGROUND: Knowledge of the mineral composition of the causative urolith is important to develop preventative strategies. Advances in analytic techniques have led to detection of urolith components not previously recognized. HYPOTHESIS/OBJECTIVES: The objectives of this study were to characterize uroliths in sheep and goats structurally and clinically. We hypothesized that amorphous magnesium calcium phosphate (AMCP) would be a naturally occurring urolith type in sheep and goats...
May 29, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28556454/genetics-of-hereditary-ataxia-in-scottish-terriers
#19
G Urkasemsin, D M Nielsen, A Singleton, S Arepalli, D Hernandez, C Agler, N J Olby
BACKGROUND: Scottish Terriers have a high incidence of juvenile onset hereditary ataxia primarily affecting the Purkinje neuron of the cerebellar cortex and causing slowly progressive cerebellar dysfunction. OBJECTIVE: To identify chromosomal regions associated with hereditary ataxia in Scottish Terriers. ANIMALS: One hundred and fifty-three Scottish Terriers were recruited through the Scottish Terrier Club of America. MATERIALS AND METHODS: Prospective study...
May 29, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28556471/putative-cerebral-microbleeds-in-dogs-undergoing-magnetic-resonance-imaging-of-the-head-a-retrospective-study-of-demographics-clinical-associations-and-relationship-to-case-outcome
#20
S C Kerwin, J M Levine, C M Budke, J F Griffin, C E Boudreau
BACKGROUND: Cerebral microbleeds (CMBs) are focal intraparenchymal signal voids on gradient-echo magnetic resonance imaging (MRI), corresponding to regions of chronic hemorrhage. In humans, they are associated with systemic disease and shorter survival times. Although similar findings have been identified in dogs, their epidemiology and clinical correlations have not been investigated. OBJECTIVE: To determine epidemiological features, clinical associations, and associations with outcome for putative CMB-like foci (putative microbleeds [pMBs]) identified by T2*-weighted MRI in dogs...
May 27, 2017: Journal of Veterinary Internal Medicine
journal
journal
29590
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"