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Rajani Sebastian, Carol B Thompson, Nae-Yuh Wang, Amy Wright, Aaron Meyer, Rhonda B Friedman, Argye E Hillis, Donna C Tippett
Background: Individuals with primary progressive aphasia (PPA) and their caregivers want to know what to expect so that they can plan support appropriately. The ability to predict decline in naming and semantic knowledge, and advise individuals with PPA and their caregivers regarding future planning, would be invaluable clinically. Aims: The aims of this study were to investigate patterns of decline in naming and semantic knowledge in each of the clinical variants of PPA (logopenic variant PPA, lvPPA; nonfluent agrammatic PPA, nfaPPA; and semantic variant PPA, svPPA) and to examine the effects of other variables on rate of decline...
2018: Aphasiology
Dirk-Bart den Ouden, Elena Galkina, Alexandra Basilakos, Julius Fridriksson
Background: Apraxia of Speech (AOS) has been associated with deviations in consonantal voice-onset-time (VOT), but studies of vowel acoustics have yielded conflicting results. However, a speech motor planning disorder that is not bound by phonological categories is expected to affect vowel as well as consonant articulations. Aims: We measured consonant VOTs and vowel formants produced by a large sample of stroke survivors, and assessed to what extent these variables and their dispersion are predictive of AOS presence and severity, based on a scale that uses clinical observations to rate gradient presence of AOS, aphasia, and dysarthria...
2018: Aphasiology
Charltien Long, Rajani Sebastian, Andreia V Faria, Argye E Hillis
Background: Functional neuroimaging techniques can provide a unique window into the neural basis of language recovery after a stroke. The functional neuroimaging literature on post-stroke language recovery is complex; multiple factors such as the time post-stroke, degree of initial impairment, nature of the task, and lesion location and size, influence recovery patterns. Some of these factors may not be applicable across different stroke participants, and therefore, influence recovery trajectories in vastly different manners across patients...
2018: Aphasiology
Jennifer DiLallo, Heidi Mettler, Gayle DeDe
Background: This study investigated whether individuals with aphasia (IWA) retain verb biases in expressive language. Verb biases refer to the likelihood that a given verb will occur in different sentence structures. We focused on the likelihood of verbs occurring in transitive and intransitive structures. Aims: The main goal of this study was to determine whether IWA and controls show similar verb biases or whether IWA show a preference for transitive or intransitive structures that supersedes individual verb biases...
2017: Aphasiology
Aaron M Meyer, Andreia V Faria, Donna C Tippett, Argye E Hillis, Rhonda B Friedman
Background: Structural imaging has not been used previously to predict the effect of treatment in primary progressive aphasia (PPA). Aims: This study examined relationships between baseline brain volume and the effects of phonological and orthographic treatments for anomia in PPA. It was predicted that lower baseline volume would be associated with lower post-treatment naming accuracy for treated items and smaller generalization effects. Methods & Procedures: Twenty-one individuals with PPA participated...
2017: Aphasiology
Angelica McCarron, Ashley Chavez, Miranda Babiak, Mitchel S Berger, Edward F Chang, Stephen M Wilson
BACKGROUND: Transient aphasias are common in the first few days after resective surgery to the language-dominant hemisphere. The specific speech and language deficits that occur are related to the location of the surgical site, and may include impairments in fluency, lexical access, repetition, and comprehension. The impact of these transient aphasias on connected speech production has not previously been investigated. AIMS: The goals of this study were to characterize the nature of connected speech deficits in the immediate post-surgical period, and to determine which deficits resolve completely within 1 month...
2017: Aphasiology
Stephanie A Yagata, Melodie Yen, Angelica McCarron, Alexa Bautista, Genevieve Lamair-Orosco, Stephen M Wilson
BACKGROUND: Aphasia following infarction of Wernicke's area typically resolves to some extent over time. The nature of this recovery process and its time course have not been characterized in detail, especially in the acute/subacute period. AIMS: The goal of this study was to document recovery after infarction of Wernicke's area in detail in the first 3 months after stroke. Specifically, we aimed to address two questions about language recovery. First, which impaired language domains improve over time, and which do not? Second, what is the time course of recovery? METHODS & PROCEDURES: We used quantitative analysis of connected speech and a brief aphasia battery to document language recovery in two individuals with aphasia following infarction of the posterior superior temporal gyrus...
2017: Aphasiology
Natalie Sullivan, Matthew Walenski, Tracy Love, Lewis P Shapiro
BACKGROUND: Individuals with agrammatic Broca's aphasia (IWBA) exhibit a delay in lexical activation in S-V-O word order sentences and delayed lexical reactivation in sentences that contain syntactic dependencies. This pattern is in contrast to neurologically unimpaired individuals who immediately evince lexical reactivation at the gap in sentences that contain syntactic dependencies. However, in the case of sentences that contain unaccusative verbs, neurologically unimpaired individuals also exhibit a delay in lexical reactivation...
2017: Aphasiology
Claire Cordella, Bradford C Dickerson, Megan Quimby, Yana Yunusova, Jordan R Green
BACKGROUND: Primary progressive aphasia (PPA) is a neurodegenerative aphasic syndrome with three distinct clinical variants: non-fluent (nfvPPA), logopenic (lvPPA), and semantic (svPPA). Speech (non-) fluency is a key diagnostic marker used to aid identification of the clinical variants, and researchers have been actively developing diagnostic tools to assess speech fluency. Current approaches reveal coarse differences in fluency between subgroups, but often fail to clearly differentiate nfvPPA from the variably fluent lvPPA...
2017: Aphasiology
Audrey Holland, Davida Fromm, Margaret Forbes, Brian MacWhinney
BACKGROUND: This work focuses on the twenty-six individuals who provided data to AphasiaBank on at least two occasions, with initial testing between 6 months and 5.8 years post-onset of aphasia. The data are archival in nature and were collected from the extensive database of aphasic discourse in AphasiaBank. AIMS: The aim is to furnish data on the nature of long-term changes in both the impairment of aphasia as measured by the Western Aphasia Battery-Revised (WAB-R) and its expression in spoken discourse...
2017: Aphasiology
Laura Mary McCarthy, Michelene Kalinyak-Fliszar, Francine Kohen, Nadine Martin
BACKGROUND: Deep dysphasia is a relatively rare subcategory of aphasia, characterised by word repetition impairment and a profound auditory-verbal short-term memory (STM) limitation. Repetition of words is better than nonwords (lexicality effect) and better for high-image than low-image words (imageability effect). Another related language impairment profile is phonological dysphasia, which includes all of the characteristics of deep dysphasia except for the occurrence of semantic errors in single word repetition...
2017: Aphasiology
Julia Schuchard, Michaela Nerantzini, Cynthia K Thompson
BACKGROUND: Implicit learning is a process of learning that occurs outside of conscious awareness and may be involved in implicit, exposure-based language training. However, research shows that implicit learning abilities are variable among individuals with aphasia, and it remains unknown whether individuals who show basic implicit learning abilities also benefit from implicit language training. AIMS: The aims of this series of experiments were to test implicit learning in individuals with agrammatic aphasia, examine the effects of a novel implicit language treatment, and investigate whether individuals with aphasia who show implicit learning ability also benefit from implicit treatment focused on passive sentence comprehension...
2017: Aphasiology
Natalie Sullivan, Matthew Walenski, Tracy Love, Lewis P Shapiro
BACKGROUND: It is well accepted that individuals with agrammatic Broca's aphasia have difficulty comprehending some sentences with filler-gap dependencies. While investigations of these difficulties have been conducted with several different sentence types (e.g., object relatives, Wh-questions), we explore sentences containing unaccusative verbs, which arguably have a single noun phrase (NP) that is base-generated in object position but then is displaced to surface subject position. Unaccusative verbs provide an ideal test case for a particular hypothesis about the comprehension disorder-the Intervener Hypothesis-that posits that the difficulty individuals with agrammatic Broca's aphasia have comprehending sentences containing filler-gap dependencies results from similarity-based interference caused by the presence of an intervening NP between the two elements of a syntactic chain...
2017: Aphasiology
Robyn L Tate, Michael Perdices, Ulrike Rosenkoetter, William Shadish, Sunita Vohra, David H Barlow, Robert Horner, Alan Kazdin, Thomas Kratochwill, Skye McDonald, Margaret Sampson, Larissa Shamseer, Leanne Togher, Richard Albin, Catherine Backman, Jacinta Douglas, Jonathan J Evans, David Gast, Rumen Manolov, Geoffrey Mitchell, Lyndsey Nickels, Jane Nikles, Tamara Ownsworth, Miranda Rose, Christopher H Schmid, Barbara Wilson
We developed a reporting guideline to provide authors with guidance about what should be reported when writing a paper for publication in a scientific journal using a particular type of research design: the single-case experimental design. This report describes the methods used to develop the Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016. As a result of 2 online surveys and a 2-day meeting of experts, the SCRIBE 2016 checklist was developed, which is a set of 26 items that authors need to address when writing about single-case research...
July 2, 2016: Aphasiology
Julia Carpenter, Leora R Cherney
BACKGROUND: Intensity of therapy is a critical factor influencing outcomes in aphasia. However, there are many barriers to increasing treatment intensity for those with acute/subacute aphasia including the demands of the inpatient medical facilities and the endurance of the participants. Nevertheless, with some modifications to its original procedures, evidence suggests that Constraint Induced Language Therapy (CILT) may yield positive outcomes when given in the early stages of recovery...
May 1, 2016: Aphasiology
Aaron M Meyer, Heidi R Getz, David M Brennan, Tang M Hu, Rhonda B Friedman
BACKGROUND: The efficacy of telerehabilitation-based treatment for anomia has been demonstrated in post-stroke aphasia, but the efficacy of this method of anomia treatment delivery has not been established within the context of degenerative illness. AIMS: The current study evaluated the feasibility and efficacy of a telerehabilitation-based approach to anomia treatment within the three subtypes of primary progressive aphasia (PPA). METHODS & PROCEDURES: Each of the three telerehabilitation participants represented a distinct subtype of PPA...
April 1, 2016: Aphasiology
Catherine A Off, Jenna R Griffin, Kristie A Spencer, Margaret Rogers
BACKGROUND: Although aphasia rehabilitation has been shown to be efficacious, many questions remain regarding how best to deliver treatment to maximize functional gains for persons with aphasia. Treatment delivery variables, such as intensity and dosage, are likely to influence both behavioral and structural changes during anomia treatment. While numerous protocols have concluded that treatment intensity positively impacts functional outcomes, few studies to date have examined the role that dose plays in patient outcomes for anomia treatment...
2016: Aphasiology
Honglei Wang, Cynthia K Thompson
BACKGROUND: English-speaking patients with Broca's aphasia and agrammatism evince difficulty with complex grammatical structures, including verbs and sentences. A few studies have found similar patterns among Chinese-speaking patients with broca's aphasia, despite structural differences between these two languages. However, no studies have explicitly examined verb properties, including the number and optionality of arguments (participant roles) selected by the verb, and only a few studies have examined sentence deficits among Chinese patients...
2016: Aphasiology
Stephen Kintz, Heather Harris Wright, Gerasimos Fergadiotis
BACKGROUND: Researchers have demonstrated that people with aphasia (PWA) have preserved semantic knowledge (Dell et al., 1997; Jefferies & Lambon Ralph, 2006). However, Antonucci (2014) demonstrated that some PWA have impaired access to certain types of knowledge more than others. Yet, all these studies used single concepts. It has not been demonstrated whether PWA have difficulty accessing certain types of features within a discourse sample. AIMS: The main goals of this study were to determine if semantic knowledge and two category types were used differently within discourse produced by participants with anomic aphasia and healthy controls...
2016: Aphasiology
Erin L Meier, Melody Lo, Swathi Kiran
BACKGROUND: Semantic and phonological processing deficits are often present in aphasia. The degree of interdependence between the deficits has been widely studied with variable findings. Semantic variables such as category and typicality have been found to influence semantic processing in healthy individuals and persons with aphasia but their influence on phonological processing is unknown. AIMS: This study examined the nature of semantic and phonological access in aphasia by comparing adults with aphasia to healthy control participants...
2016: Aphasiology
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