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Natalie Sullivan, Matthew Walenski, Tracy Love, Lewis P Shapiro
BACKGROUND: It is well accepted that individuals with agrammatic Broca's aphasia have difficulty comprehending some sentences with filler-gap dependencies. While investigations of these difficulties have been conducted with several different sentence types (e.g., object relatives, Wh-questions), we explore sentences containing unaccusative verbs, which arguably have a single noun phrase (NP) that is base-generated in object position but then is displaced to surface subject position. Unaccusative verbs provide an ideal test case for a particular hypothesis about the comprehension disorder-the Intervener Hypothesis-that posits that the difficulty individuals with agrammatic Broca's aphasia have comprehending sentences containing filler-gap dependencies results from similarity-based interference caused by the presence of an intervening NP between the two elements of a syntactic chain...
2017: Aphasiology
Robyn L Tate, Michael Perdices, Ulrike Rosenkoetter, William Shadish, Sunita Vohra, David H Barlow, Robert Horner, Alan Kazdin, Thomas Kratochwill, Skye McDonald, Margaret Sampson, Larissa Shamseer, Leanne Togher, Richard Albin, Catherine Backman, Jacinta Douglas, Jonathan J Evans, David Gast, Rumen Manolov, Geoffrey Mitchell, Lyndsey Nickels, Jane Nikles, Tamara Ownsworth, Miranda Rose, Christopher H Schmid, Barbara Wilson
We developed a reporting guideline to provide authors with guidance about what should be reported when writing a paper for publication in a scientific journal using a particular type of research design: the single-case experimental design. This report describes the methods used to develop the Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016. As a result of 2 online surveys and a 2-day meeting of experts, the SCRIBE 2016 checklist was developed, which is a set of 26 items that authors need to address when writing about single-case research...
July 2, 2016: Aphasiology
Julia Carpenter, Leora R Cherney
BACKGROUND: Intensity of therapy is a critical factor influencing outcomes in aphasia. However, there are many barriers to increasing treatment intensity for those with acute/subacute aphasia including the demands of the inpatient medical facilities and the endurance of the participants. Nevertheless, with some modifications to its original procedures, evidence suggests that Constraint Induced Language Therapy (CILT) may yield positive outcomes when given in the early stages of recovery...
May 1, 2016: Aphasiology
Aaron M Meyer, Heidi R Getz, David M Brennan, Tang M Hu, Rhonda B Friedman
BACKGROUND: The efficacy of telerehabilitation-based treatment for anomia has been demonstrated in post-stroke aphasia, but the efficacy of this method of anomia treatment delivery has not been established within the context of degenerative illness. AIMS: The current study evaluated the feasibility and efficacy of a telerehabilitation-based approach to anomia treatment within the three subtypes of primary progressive aphasia (PPA). METHODS & PROCEDURES: Each of the three telerehabilitation participants represented a distinct subtype of PPA...
April 1, 2016: Aphasiology
Catherine A Off, Jenna R Griffin, Kristie A Spencer, Margaret Rogers
BACKGROUND: Although aphasia rehabilitation has been shown to be efficacious, many questions remain regarding how best to deliver treatment to maximize functional gains for persons with aphasia. Treatment delivery variables, such as intensity and dosage, are likely to influence both behavioral and structural changes during anomia treatment. While numerous protocols have concluded that treatment intensity positively impacts functional outcomes, few studies to date have examined the role that dose plays in patient outcomes for anomia treatment...
2016: Aphasiology
Honglei Wang, Cynthia K Thompson
BACKGROUND: English-speaking patients with Broca's aphasia and agrammatism evince difficulty with complex grammatical structures, including verbs and sentences. A few studies have found similar patterns among Chinese-speaking patients with broca's aphasia, despite structural differences between these two languages. However, no studies have explicitly examined verb properties, including the number and optionality of arguments (participant roles) selected by the verb, and only a few studies have examined sentence deficits among Chinese patients...
2016: Aphasiology
Stephen Kintz, Heather Harris Wright, Gerasimos Fergadiotis
BACKGROUND: Researchers have demonstrated that people with aphasia (PWA) have preserved semantic knowledge (Dell et al., 1997; Jefferies & Lambon Ralph, 2006). However, Antonucci (2014) demonstrated that some PWA have impaired access to certain types of knowledge more than others. Yet, all these studies used single concepts. It has not been demonstrated whether PWA have difficulty accessing certain types of features within a discourse sample. AIMS: The main goals of this study were to determine if semantic knowledge and two category types were used differently within discourse produced by participants with anomic aphasia and healthy controls...
2016: Aphasiology
Erin L Meier, Melody Lo, Swathi Kiran
BACKGROUND: Semantic and phonological processing deficits are often present in aphasia. The degree of interdependence between the deficits has been widely studied with variable findings. Semantic variables such as category and typicality have been found to influence semantic processing in healthy individuals and persons with aphasia but their influence on phonological processing is unknown. AIMS: This study examined the nature of semantic and phonological access in aphasia by comparing adults with aphasia to healthy control participants...
2016: Aphasiology
Tepanta R D Fossett, Malcolm R McNeil, Sheila R Pratt, Connie A Tompkins, Linda I Shuster
BACKGROUND: Although many speech errors can be generated at either a linguistic or motoric level of production, phonetically well-formed sound-level serial-order errors are generally assumed to result from disruption of phonologic encoding (PE) processes. An influential model of PE (Dell, 1986; Dell, Burger & Svec, 1997) predicts that speaking rate should affect the relative proportion of these serial-order sound errors (anticipations, perseverations, exchanges). These predictions have been extended to, and have special relevance for persons with aphasia (PWA) because of the increased frequency with which speech errors occur and because their localization within the functional linguistic architecture may help in diagnosis and treatment...
2016: Aphasiology
Swathi Kiran, Carrie Des Roches, Sarah Villard, Yorghos Tripodis
BACKGROUND: While it is well understood that individuals with aphasia have difficulty with discourse comprehension, very few studies have examined the nature of discourse comprehension deficits in aphasia and the potential for improvement in discourse comprehension after rehabilitation. To address the first goal, we previously developed the Test of Syntactic Effects on Discourse Comprehension (TSEDC), which provides a measure of the extent to which a participant's sentence comprehension ability aids in comprehending passages (Levy et al...
November 1, 2015: Aphasiology
Madeleine Pritchard, Lucy Dipper, Gary Morgan, Naomi Cocks
Background: Conveying instructions is an everyday use of language, and gestures are likely to be a key feature of this. Although co-speech iconic gestures are tightly integrated with language, and people with aphasia (PWA) produce procedural discourses impaired at a linguistic level, no previous studies have investigated how PWA use co-speech iconic gestures in these contexts. Aims: This study investigated how PWA communicated meaning using gesture and language in procedural discourses, compared with neurologically healthy people (NHP)...
July 3, 2015: Aphasiology
Suzanne Beeke, Firle Beckley, Fiona Johnson, Claudia Heilemann, Susan Edwards, Jane Maxim, Wendy Best
Background: A recent review of interaction (or conversation)-focused therapy highlighted the potential of programmes targeting the person with aphasia (PWA) directly. However, it noted the key limitations of current work in this field to be a reliance on single case analyses and qualitative evidence of change, a situation that is not unusual when a complex behavioural intervention is in the early stages of development and evaluation. Aims: This article aims to evaluate an intervention that targeted a PWA and their conversation partner (CP), a dyad, as equals in a novel conversation therapy for agrammatic aphasia, using both quantitative and qualitative evidence of change...
March 4, 2015: Aphasiology
Ellyn A Riley, Cynthia K Thompson
BACKGROUND: Individuals with acquired phonological dyslexia experience difficulty associating written letters with corresponding sounds, especially in pseudowords. Previous studies have shown that reading can be improved in these individuals by training letter-sound correspondence, practicing phonological skills, or using combined approaches. However, generalization to untrained items is typically limited. AIMS: We investigated whether principles of phonological complexity can be applied to training letter-sound correspondence reading in acquired phonological dyslexia to improve generalization to untrained words...
February 1, 2015: Aphasiology
Jiyeon Lee, Cynthia K Thompson
BACKGROUND: Phonological priming has been shown to facilitate naming in individuals with aphasia as well as healthy speakers, resulting in faster naming latencies. However, the mechanisms of phonological facilitation (PF) in aphasia remain unclear. AIMS: Within discrete vs. interactive models of lexical access, this study examined whether PF occurs via the sub-lexical or lexical route during noun and verb naming in agrammatic and anomic aphasia. METHODS AND PROCEDURES: Thirteen participants with agrammatic aphasia and 10 participants with anomic aphasia and their young and age-matched controls (n=20/each) were tested...
2015: Aphasiology
Aaron M Meyer, Sarah F Snider, Carol B Eckmann, Rhonda B Friedman
BACKGROUND: Treatment studies for anomia in PPA have rarely compared multiple treatments in the same individual, and few anomia treatment studies have included participants with the logopenic variant of PPA (lvPPA). AIMS: The goals of this study were to evaluate two types of treatment for anomia in a bilingual participant (ND) with lvPPA, and to examine possible cross-language transfer of treatment effects. METHODS & PROCEDURES: ND is a Norwegian-English bilingual woman with lvPPA who began this study at the age of 69...
2015: Aphasiology
Sam-Po Law, Anthony Pak-Hin Kong, Loretta Wing-Shan Lai, Christy Lai
BACKGROUND: Differences in processing nouns and verbs have been investigated intensely in psycholinguistics and neuropsychology in past decades. However, the majority of studies examining retrieval of these word classes have involved tasks of single word stimuli or responses. While the results have provided rich information for addressing issues about grammatical class distinctions, it is unclear whether they have adequate ecological validity for understanding lexical retrieval in connected speech which characterizes daily verbal communication...
January 2015: Aphasiology
Marian C Brady, Myzoon Ali, Chrysovalantis Fyndanis, Maria Kambanaros, Kleanthes K Grohmann, Anne-Charlotte Laska, Carlos Hernández-Sacristán, Spyridoula Varlokosta
No abstract text is available yet for this article.
November 2, 2014: Aphasiology
Cynthia K Thompson, Jennifer E Mack
BACKGROUND: Grammatical impairments are commonly observed in the agrammatic subtype of primary progressive aphasia (PPA-G), whereas grammatical processing is relatively preserved in logopenic (PPA-L) and semantic (PPA-S) subtypes. AIMS: We review research on grammatical deficits in PPA and associated neural mechanisms, with discussion focused on production and comprehension of four aspects of morphosyntactic structure: grammatical morphology, functional categories, verbs and verb argument structure, and complex syntactic structures...
September 2014: Aphasiology
Murray Grossman
BACKGROUND: Primary progressive aphasia (PPA) is a progressive disorder of language that is increasingly recognised as an important presentation of a specific spectrum of neurodegenerative conditions. AIMS: In an era of etiologically specific treatments for neurodegenerative conditions, it is crucial to establish the histopathologic basis for PPA. In this review, I discuss biomarkers for identifying the pathology underlying PPA. MAIN CONTRIBUTION: Clinical syndromes suggest a probabilistic association between a specific PPA variant and an underlying pathology, but there are also many exceptions...
September 2014: Aphasiology
Andreia V Faria, Rajani Sebastian, Melissa Newhart, Susumu Mori, Argye E Hillis
BACKGROUND: Three variants of primary progressive aphasia (PPA), distinguished by language performance and supportive patterns of atrophy on imaging, have different clinical courses and the prognoses for specific functions. For example, semantic variant PPA alone is distinguished by impaired word comprehension. However, sometimes individuals with high education show normal performance on word comprehension tests early on, making classification difficult. Furthermore, as the condition progresses, individuals with other variants develop word comprehension deficits and other behavioral symptoms, making distinctions between variants less clear...
August 2014: Aphasiology
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