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Functional Neurology

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https://www.readbyqxmd.com/read/27900929/main-effects-and-interactions-of-cerebral-hemispheres-gender-and-age-in-the-calculation-of-volumes-and-asymmetries-of-selected-structures-of-episodic-memory
#1
Rocio Ramirez-Carmona, Haydee Guadalupe Garcia-Lazaro, Brenda Dominguez-Corrales, Erika Aguilar-Castañeda, Ernesto Roldan-Valadez
The aim of this study was to clarify the influence of anatomical (cerebral hemisphere) and demographic (age and gender) variables on the gray matter (GM) volumes and volumetric asymmetry indices (VAIs) of selected structures involved in episodic memory. A cross-sectional study was performed in 47 healthy volunteers. Neuropsychological evaluation revealed similar IQs across the sample. Using SPM-based software, brain segmentation, labeling and volume measurements of the hippocampus, amygdala, middle temporal gyrus and parahippocampal gyrus were performed in each cerebral hemisphere...
November 30, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27781973/magnetic-resonance-imaging-and-positron-emission-tomography-in-the-diagnosis-of-neurodegenerative-dementias
#2
A Del Sole, S Malaspina, Alberto Magenta Biasina
Neuroimaging, both with magnetic resonance imaging (MRI) and positron emission tomography (PET), has gained a pivotal role in the diagnosis of primary neurodegenerative diseases. These two techniques are used as biomarkers of both pathology and progression of Alzheimer's disease (AD) and to differentiate AD from other neurodegenerative diseases. MRI is able to identify structural changes including patterns of atrophy characterizing neurodegenerative diseases, and to distinguish these from other causes of cognitive impairment, e...
October 26, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27781972/connectivity-measures-in-the-poffenberger-paradigm-indicate-hemispheric-asymmetries
#3
N Erbil, Suha Yagcioglu
The Poffenberger paradigm is a well-known measure of interhemispheric transfer delays, calculated on the basis of the crossed vs uncrossed reaction time difference (CUD). However, the proper interpretation of CUD is extensively debated in the literature. In this study we used connectivity measures in an attempt to interpret CUD from the perspective of functional connectivity. Accordingly, we tried to define functional couplings in the Poffenberger paradigm; we used a simple choice version of the paradigm, and included a stimulation only (SO) condition for comparison...
October 26, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27781971/impact-of-cerebellar-atrophy-on-cortical-gray-matter-and-cerebellar-peduncles-as-assessed-by-voxel-based-morphometry-and-high-angular-resolution-diffusion-imaging
#4
Michael Dayan, G Olivito, M Molinari, Mara Cercignani, Marco Bozzali, M Leggio
In recent years the cerebellum has been attributed amore important role in higher-level functions than previously believed. We examined a cohort of patients suffering from cerebellar atrophy resulting in ataxia, with two main objectives: first to investigate which regions of the cerebrum were affected by the cerebellar degeneration, and second to assess whether diffusion magnetic resonance imaging (dMRI) metrics within the medial (MCP) and superior cerebellar peduncle (SCP) - namely fractional anisotropy (FA) and radial diffusivity (RD) - could be used as a biomarker in patients with this condition...
October 26, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27666410/incidence-and-predictors-of-stroke-during-the-index-event-in-an-ethnically-diverse-takotsubo-cardiomyopathy-population
#5
A Dias, E Franco, S Janzer, Nikoloz Koshkelashvili, V Bhalla, Manolo Rubio, Sarah Amanullah, Kathy Hebert, Vincent M Figueredo
Takotsubo cardiomyopathy (TTS) is a peculiar clinical condition often affecting postmenopausal women after a stressful trigger. The underlying mechanisms have not been completely elucidated but several hypotheses have been advanced, with catecholamine cardiotoxicity, microvascular dysfunction and coronary artery spasm each suggested to play a role. The incidence of stroke after TTS appears to range from 0% to 7.7%, and interestingly TTS has been described as both a cause and a complication of stroke. We sought to assess the incidence and predictors of stroke during the index event (peri-index event stroke) in a heterogeneous TTS population...
September 26, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27428291/new-test-of-odor-pleasantness-in-parkinson-s-disease
#6
Kristyna Pospichalova, Jan Vodicka, Ales Kopal
The New Test of Odor Pleasantness (NTOP) evaluates the hedonicity of olfactory stimulants. The aim of this study was to compare results of the NTOP, the Sniffin' Sticks test, and the Odorized Marker Test (OMT) in patients with Parkinson's disease (PD). The study sample comprised 30 PD patients (mean age 71±7.36 years) and the control group made up of 31 non-PD subjects (mean age 68±12.39 years). Sociodemographic data, medical history and tests of cognitive function were investigated. Olfaction was evaluated using the NTOP, Sniffin' Sticks test and OMT...
July 18, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27428290/robot-assisted-gait-training-versus-treadmill-training-in-patients-with-parkinson-s-disease-a-kinematic-evaluation-with-gait-profile-score
#7
M Galli, V Cimolin, M F De Pandis, D Le Pera, I Sova, G Albertini, F Stocchi, M Franceschini
The purpose of this study was to quantitatively compare the effects, on walking performance, of end-effector robotic rehabilitation locomotor training versus intensive training with a treadmill in Parkinson's disease (PD). Fifty patients with PD were randomly divided into two groups: 25 were assigned to the robot-assisted therapy group (RG) and 25 to the intensive treadmill therapy group (IG). They were evaluated with clinical examination and 3D quantitative gait analysis [gait profile score (GPS) and its constituent gait variable scores (GVSs) were calculated from gait analysis data] at the beginning (T0) and at the end (T1) of the treatment...
July 18, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27428289/spectrum-of-cognitive-disorders-in-idiopathic-normal-pressure-hydrocephalus
#8
Marta Picascia, B Minafra, Roberta Zangaglia, L Gracardi, N G Pozzi, E Sinforiani, Claudio Pacchetti
Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by ventricular dilation accompanied by a progressive triad of a gait disturbance, "dementia" and incontinence. We retrospectively evaluated cognitive profile, and its relationship with disease variables, in 64 iNPH patients. The iNPH group performed significantly worse than the control group on all neuropsychological tests, except for verbal memory (within the normal range). The patients were subdivided into four groups: group 1 (42%: global cognitive impairment); group 2 (24%: frontosubcortical dysfunction); group 3 (17%: isolated deficit of a single cognitive domain); group 4 (17%: no cognitive impairment)...
July 18, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27428288/women-with-epilepsy-clinically-relevant-issues
#9
S Bangar, Abhishek Shastri, Hany El-Sayeh, Andrea E Cavanna
Women with epilepsy (WWE) face specific challenges throughout their lifespan due to the effects of seizures and antiepileptic drugs on hormonal function, potentially affecting both sexual and reproductive health. This review article addresses the most common issues of practical relevance to clinicians treating WWE: epidemiology and clinical presentations (including catamenial epilepsy), contraception, reproductive and sexual dysfunction, pregnancy, lactation, menopause-related issues (including bone health), and mental health aspects...
July 18, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678213/what-is-cluster-headache-fact-sheet-for-patients-and-their-families-a-publication-to-mark-cluster-headache-day-2016
#10
Paolo Rossi, J Whelan, A Craven, E Ruiz De La Torre
No abstract text is available yet for this article.
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678212/post-stroke-spasticity-as-a-condition-a-new-perspective-on-patient-evaluation
#11
LETTER
A Baricich, A Picelli, F Molteni, E Guanziroli, Andrea Santamato
No abstract text is available yet for this article.
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678211/frailty-and-resilience-in-an-older-population-the-role-of-resilience-during-rehabilitation-after-orthopedic-surgery-in-geriatric-patients-with-multiple-comorbidities
#12
G A A Rebagliati, L Sciumè, P Iannello, A Mottini, A Antonietti, V A Caserta, V Gattoronchieri, Lorenzo Panella, Camilla Callegari
Hip fracture is common in the elderly and it is usually associated with comorbidities and physiological changes which may have an impact on functioning and quality of life. The concept of resilience may explain why this impact varies among patients. The aim of this open, prospective cohort study was to explore the relationships between resilience, frailty and quality of life in orthopedic rehabilitation patients, and also to assess whether these factors might affect rehabilitation outcome. Eighty-one patients, older than 60 years, underwent a multidisciplinary assessment at the beginning and at the end of the rehabilitation period following orthopedic surgery to the lower limb...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678210/robot-assisted-gait-training-versus-treadmill-training-in-patients-with-parkinson-s-disease-a-kinematic-evaluation-with-gait-profile-score
#13
M Galli, V Cimolin, M F De Pandis, D Le Pera, I Sova, G Albertini, F Stocchi, M Franceschini
The purpose of this study was to quantitatively compare the effects, on walking performance, of end-effector robotic rehabilitation locomotor training versus intensive training with a treadmill in Parkinson's disease (PD). Fifty patients with PD were randomly divided into two groups: 25 were assigned to the robot-assisted therapy group (RG) and 25 to the intensive treadmill therapy group (IG). They were evaluated with clinical examination and 3D quantitative gait analysis [gait profile score (GPS) and its constituent gait variable scores (GVSs) were calculated from gait analysis data] at the beginning (T0) and at the end (T1) of the treatment...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678209/incidence-and-predictors-of-stroke-during-the-index-event-in-an-ethnically-diverse-takotsubo-cardiomyopathy-population
#14
A Dias, E Franco, S Janzer, Nikoloz Koshkelashvili, V Bhalla, Manolo Rubio, Sarah Amanullah, Kathy Hebert, Vincent M Figueredo
Takotsubo cardiomyopathy (TTS) is a peculiar clinical condition often affecting postmenopausal women after a stressful trigger. The underlying mechanisms have not been completely elucidated but several hypotheses have been advanced, with catecholamine cardiotoxicity, microvascular dysfunction and coronary artery spasm each suggested to play a role. The incidence of stroke after TTS appears to range from 0% to 7.7%, and interestingly TTS has been described as both a cause and a complication of stroke. We sought to assess the incidence and predictors of stroke during the index event (peri-index event stroke) in a heterogeneous TTS population...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678208/new-test-of-odor-pleasantness-in-parkinson-s-disease
#15
Kristyna Pospichalova, Jan Vodicka, Ales Kopal
The New Test of Odor Pleasantness (NTOP) evaluates the hedonicity of olfactory stimulants. The aim of this study was to compare results of the NTOP, the Sniffin' Sticks test, and the Odorized Marker Test (OMT) in patients with Parkinson's disease (PD). The study sample comprised 30 PD patients (mean age 71±7.36 years) and the control group made up of 31 non-PD subjects (mean age 68±12.39 years). Sociodemographic data, medical history and tests of cognitive function were investigated. Olfaction was evaluated using the NTOP, Sniffin' Sticks test and OMT...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678207/spectrum-of-cognitive-disorders-in-idiopathic-normal-pressure-hydrocephalus
#16
Marta Picascia, B Minafra, Roberta Zangaglia, L Gracardi, N G Pozzi, E Sinforiani, Claudio Pacchetti
Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by ventricular dilation accompanied by a progressive triad of a gait disturbance, "dementia" and incontinence. We retrospectively evaluated cognitive profile, and its relationship with disease variables, in 64 iNPH patients. The iNPH group performed significantly worse than the control group on all neuropsychological tests, except for verbal memory (within the normal range). The patients were subdivided into four groups: group 1 (42%: global cognitive impairment); group 2 (24%: frontosubcortical dysfunction); group 3 (17%: isolated deficit of a single cognitive domain); group 4 (17%: no cognitive impairment)...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678206/clinical-and-genetic-investigation-of-a-brazilian-family-with-huntington-s-disease
#17
L A Agostinho, M Spitz, J S Pereira, C L A Paiva
The aim of this study was to investigate a Brazilian family carrying full penetrance alleles for Huntington's disease (HD) in order to correlate each member's genetic and clinical features. To this end, the following scales were administered in each patient: the Beck Depression Inventory, the Mini-Mental State Examination (MMSE) and the Unified Huntington's Disease Rating Scale (UHDRS). The patterns of CAG and CCG polymorphic regions in the HTT gene were determined, the disease burden score was calculated, and genotypes were correlated with phenotypes within this family...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678205/women-with-epilepsy-clinically-relevant-issues
#18
S Bangar, Abhishek Shastri, Hany El-Sayeh, Andrea E Cavanna
Women with epilepsy (WWE) face specific challenges throughout their lifespan due to the effects of seizures and antiepileptic drugs on hormonal function, potentially affecting both sexual and reproductive health. This review article addresses the most common issues of practical relevance to clinicians treating WWE: epidemiology and clinical presentations (including catamenial epilepsy), contraception, reproductive and sexual dysfunction, pregnancy, lactation, menopause-related issues (including bone health), and mental health aspects...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27678204/women-with-epilepsy
#19
EDITORIAL
A Sharma, F Boller, M Koubeissi
No abstract text is available yet for this article.
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27358225/clinical-effects-of-non-invasive-cerebellar-magnetic-stimulation-treatment-combined-with-neuromotor-rehabilitation-in-traumatic-brain-injury-a-single-case-study
#20
Alex Martino Cinnera, S Bonnì, M Iosa, V Ponzo, A Fusco, Carlo Caltagirone, Giacomo Koch
Multimodal treatments are emerging as effective approaches for motor recovery in traumatic brain injury (TBI). Various evidence has demonstrated that repetitive transcranial magnetic stimulation (rTMS) may improve outcomes in people with motor disorders. Behavioral gains from rTMS protocols may be maximized when brain stimulation is coupled with carefully designed occupational/physical therapy. We present the case of a 25-year-old man with chronic TBI (a bilateral corticosubcortical parieto-occipital lesion) who underwent three weeks of cerebellar intermittent theta burst stimulation (iTBS), a form of rTMS, combined with neurorehabilitation treatment...
April 2016: Functional Neurology
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