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Acta Radiologica

Ying Kan, Wei Wang, Jie Liu, Jigang Yang, Zhenchang Wang
Background Fever of unknown origin (FUO) and inflammation of unknown origin (IUO) are challenging medical problems. Previous studies have shown that 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) plays an important role in the diagnosis of FUO, but few studies have explored this diagnostic technique in relation to IUO. Purpose To systematically review and perform a meta-analysis of published data on the diagnostic performance of PET/CT in the diagnosis of FUO and IUO...
September 11, 2018: Acta Radiologica
Yaqi Shen, Frank L Goerner, Johannes T Heverhagen, Christopher Snyder, Daoyu Hu, Xiaoming Li, Val M Runge
Background The availability of data in the medical literature for the T2 relaxivities of the Gd-based contrast agents (GBCAs) is limited. A comprehensive comparison between the agents available commercially (other than in Europe) is lacking, with no data available that most closely reflect the clinic, which is in human whole blood at body temperature. Purpose To complement the existing literature by determining T2 relaxivity data for eight GBCAs in vitro. Material and Methods The relaxivities of eight GBCAs diluted in human whole blood at 1...
September 11, 2018: Acta Radiologica
Yao Li, Xiangyang Wang, Kaixia Jiang, Jiaoxiang Chen, Yan Lin, Yaosen Wu
Background Percutaneous kyphoplasty (PKP) has been widely used to osteoporotic vertebral compression fractures (OVCFs). No previous investigations have reported the incidence and risk factors of facet joint violation (FJV) caused by PKP. Purpose To determine the incidence and risk factors of FJV following PKP in patients with OVCFs. Material and Methods We reviewed a total of 153 patients who underwent bilateral PKP. Postoperative computed tomography (CT) scans were assessed to determine the degree of FJV owing to invasion by a puncture trocar...
September 11, 2018: Acta Radiologica
Ulrik Carling, Bård Røsok, Pål-Dag Line, Eric J Dorenberg
Background Treatment outcome for hepatocellular carcinoma (HCC) is related to tumor burden and liver function. Grading systems assessing liver function need validation in different clinical settings. Purpose To evaluate drug-eluting embolic transarterial chemoembolization (DEE-TACE) in Child-Pugh A HCC with respect to albumin-bilirubin (ALBI) and platelet-albumin-bilirubin (P-ALBI) grade. Material and Methods Forty-nine patients with Child-Pugh class A, diagnosed with HCC and allocated to DEE-TACE treatment, were retrospectively analyzed regarding tumor and treatment characteristics, radiological response (mRECIST) one month post treatment, overall survival (OS), and adverse events (AEs; CTCAE, grades ≥3) with respect to ALBI and P-ALBI grade...
September 11, 2018: Acta Radiologica
Shu Min Tao, Fan Zhou, U Joseph Schoepf, Addison A Johnson, Zhu Xiao Lin, Chang Sheng Zhou, Guang Ming Lu, Long Jiang Zhang
Background As abdominal computed tomography (CT) radiation dose can be higher compared with other organ systems, monitoring the radiation exposure from this exam type is especially important. Purpose To evaluate the effect of abdominal contrast-enhanced CT (CE-CT) on levels of DNA double-strand breaks (DSBs) in peripheral blood lymphocytes. Material and Methods This study was performed in two parts: (i) an in vitro study: venous blood samples from 12 volunteers were divided into four groups. Samples in group A did not undergo radiation exposure, while groups B, C, and D received one CT scan with 1-3 times the radiation dose equivalent to abdominal CE-CT scan, respectively; and (ii) an in vivo study: blood was taken before CT and 5 min after CT in 30 patients...
September 10, 2018: Acta Radiologica
Jill Abrigo, Lin Shi, Yishan Luo, Qianyun Chen, Winnie Chiu Wing Chu, Vincent Chung Tong Mok
Background One significant barrier to incorporate Alzheimer's disease (AD) imaging biomarkers into diagnostic criteria is the lack of standardized methods for biomarker quantification. The European Alzheimer's Disease Consortium-Alzheimer's Disease Neuroimaging Initiative (EADC-ADNI) Harmonization Protocol project provides the most authoritative guideline for hippocampal definition and has produced a manually segmented reference dataset for validation of automated methods. Purpose To validate automated hippocampal volumetry using AccuBrain™, against the EADC-ADNI dataset, and assess its diagnostic performance for differentiating AD and normal aging in an independent cohort...
September 5, 2018: Acta Radiologica
Isabelle De Kock, Louke Delrue, Clarisse Lecluyse, Pieter Hindryckx, Martine De Vos, Geert Villeirs
Background Assessment of Crohn's disease (CD) activity is important to identify patients with active inflammation for therapy management. Quantitative analysis can provide objective measurement of disease presence. Purpose To evaluate the feasibility of quantitative analysis of contrast-enhanced dual-energy computed tomography (DECT) data in detection of small bowel inflammation in patients with CD with an emphasis on iodine quantification. Material and Methods DECT enterography was prospectively performed in 20 patients with active CD and in 20 healthy individuals, as the control group...
September 5, 2018: Acta Radiologica
Dong Kyu Kim, Jong Yun Won, Sung Yoon Park
Background Usefulness of ultrasound (US)-guided mass targeting and computed tomography (CT)-guided ice-ball monitoring in percutaneous cryoablation (PCA) for renal cell carcinoma (RCC) is still uncertain. Purpose To assess radiation dose and short-term outcomes of PCA for RCC using US-guided targeting and CT-guided ice-ball monitoring. Material and Methods Thirty-nine consecutive patients who underwent PCA for biopsy-proven RCC were included. Mass targeting was performed with US and ice-ball was monitored with CT guidance...
August 27, 2018: Acta Radiologica
Jens Goronzy, Sophia Blum, Albrecht Hartmann, Verena Plodeck, Lea Franken, Klaus-Peter Günther, Falk Thielemann
Background Appropriate three-dimensional imaging of the hip joint is a substantial prerequisite for planning and performing surgical correction of deformities. Although surgeons still use computed tomography (CT), modern and fast acquisition techniques of volumetric imaging using magnetic resonance imaging (MRI) for pelvic measurements enable similar resolution. Purpose This study was designed to determine if already described measures of acetabular morphology are comparable in both techniques and if assessment can be performed with equal intra-observer and inter-observer reliability...
August 27, 2018: Acta Radiologica
Ji Zhang, Weizhong Tian, Xinhua Bu, Xiulan Wang, Fangzheng Tian, Linyun Wu
Background Patients with uterine cervical cancer suffer high mortality. Accurate detection of a residual tumor by magnetic resonance imaging (MRI) during and after directed brachytherapy (BCT) is crucial for the success of cancer treatment and is a significant predictor of patient survival. Purpose To determine the diagnostic significance of MRI in detecting residual tumor tissue after BCT. Material and Methods The Web of Knowledge, Cochrane Library, and PubMed were systematically searched (January 1997 to December 2016) for post-brachytherapy MRI studies that measured residual tumors in patients with uterine cervical cancer...
August 27, 2018: Acta Radiologica
Christoph G Lisson, Catharina S Lisson, Sebastian Kleiner, Marc Regier, Meinrad Beer, Stefan A Schmidt
Background Iterative scatter correction (ISC) is a new technique applicable to plain radiography; comparable to iterative reconstruction for computed tomography, it promises dose reduction and image quality improvement. ISC for bedside chest X-rays has been applied and evaluated for some time and has recently been commercially offered for plain skeletal radiography. Purpose To analyze the potential of ISC for plain skeletal radiography with regard to image quality improvement, dose reduction, and replacement for an antiscatter grid...
August 27, 2018: Acta Radiologica
Malwina Kaniewska, Johannes Maria de Beus, Frank Ahlhelm, Alexander Mameghani, Karim Eid, Rahel A Kubik-Huch, Suzanne E Anderson
Background Whole spine localizers (WS-loc) of magnetic resonance imaging (MRI) are performed for enumeration of the vertebrae but they can be also used for the evaluation of the spine. Purpose To assess the accuracy of fracture detection using WS-locs of MRI and compare the findings with standard high-resolution short tau inversion recovery (STIR) sequences, and to determine whether the review of WS-locs is useful and if additional information can be gained by assessing the thoracic spine section of the WS-locs...
August 24, 2018: Acta Radiologica
Stine Hangaard, Jesper Sörensson Gade, Philip Hansen, Janus Damm Nybing, Henrik Gudbergsen, Henning Bliddal, Mikael Boesen
Background Reduction in gadolinium (Gd) contrast agents is wanted due to the uncertainty of the potential side effects. Purpose To investigate whether it is possible to reduce the contrast dose from conventional double dose to single dose when increasing the field strength from 1.5-T to 3-T for separating early cartilage degeneration from healthy cartilage, assessed by delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC). Material and Methods Nine patients with knee osteoarthritis (OA), Kellgren-Lawrence grade (KLG) 1-4, were recruited from an ongoing weight loss cohort study...
August 24, 2018: Acta Radiologica
Weipeng Zheng, Fangtian Xu, Haoyi Chen, Ning Wang, Wende Xiao, YingJie Liang, Shifeng Wen
Background Diffusion tensor imaging (DTI) provides information about water molecule diffusion in spinal cord. Purpose This study was aimed to investigate DTI changes in the different stages of compressive spinal cord induced by water-absorbing material implantation. Material and Methods The spinal cord compression was administered over the fourth cervical vertebral level in rat. Rat models were divided into five subgroups according to compression stages: sham group, group A: three-day compression rat models; group B: 12-day compression rat models; group C: 20-day compression rat models; group D: 60-day compression rat models...
August 24, 2018: Acta Radiologica
Mingming Miao, Xiangtao Lin, Zhonghe Zhang, Hui Zhao
Background The studies that described the dimensions of the normal fetal thoracic spinal canal and spinal cord on magnetic resonance imaging (MRI) are scarce. Purpose To determine the normal appearance of the fetal spinal canal and spinal cord at T12 across different gestational ages using 3.0-T MRI. Material and Methods The spines of 43 normal human fetuses, aged 15-40 weeks, were scanned by 3.0-T MRI. All specimens were scanned using a GE 3.0-T MRI scanner. Imaging of the T12 vertebrae was performed in the coronal, sagittal, and axial planes...
August 24, 2018: Acta Radiologica
Jie He, Hao Fang, Xiaona Li
Background Sex-related differences of vertebral bone marrow fat in relation to varying bone densities have not yet been evaluated although some studies have reported an inverse association of bone marrow fat and bone mineral density (BMD). Purpose To evaluate the relationship between bone marrow fat and BMD and to demonstrate the sex-related differences of the vertebral bone marrow fat in normal adults with varying bone densities. Material and Methods A total of 123 normal adult volunteers were enrolled in this study...
August 21, 2018: Acta Radiologica
Tao Yuan, Guoli Ren, Guanmin Quan, Yawu Liu
Background Evaluating the acute ischemic volume on diffusion-weighted imaging (DWI) in the middle cerebral artery (MCA) territory would predict outcome. Purpose To investigate the correlations between maximum area with restricted diffusion (MaxA), the orthogonal diameters (OD) as well as lesion volume on DWI, and to explore the role of MaxA and OD on predicting unfavorable outcome after an acute MCA ischemic stroke. Material and Methods Sixty consecutive adult patients, including modified Rankin Scale score (mRS) ≤2 (n = 31) and mRS > 2 (n = 29) groups, were retrospectively enrolled...
August 21, 2018: Acta Radiologica
Jeong Ah Hwang, Young Kon Kim, Ji Hye Min, Kyoung Doo Song, Insuk Sohn, Hyeon Seon Ahn
Background Liver magnetic resonance imaging (MRI) provides reliable diagnostic performance for detecting liver metastasis but is costly and time-consuming. Purpose To compare the diagnostic performance of non-contrast liver MRI to whole MRI using gadoxetic acid for detecting liver metastasis in patients with colorectal cancer (CRC). Material and Methods We included 175 patients with histologically confirmed 401 liver metastases and 73 benign liver lesions. A non-contrast MRI (T1-weighted, T2-weighted, and diffusion-weighted images) with or without multidetector computed tomography (MDCT) and a whole MRI (gadoxetic acid-enhanced and non-contrast MRI) were analyzed independently by two observers to detect liver metastasis using receiver operating characteristic analysis...
August 21, 2018: Acta Radiologica
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