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Journal of Cranio-maxillo-facial Surgery

Suzana Dvojakovska, Danica Popovic-Monevska, Aleksandar Grcev, Goran Pancevski, Alberto Benedetti, Vladimir Popovski, Aleksandar Dimovski, Aleksandar Stamatoski
The advancements in epigenetics of oral squamous cell carcinoma (OSCC), are made in regard to DNA hypermethylation of MGMT, DAPK, ECAD (E-cadherin) and p16, as an important component of oral carcinogenesis and new potential biomarkers in molecular diagnostic strategies. The objective of the study was to evaluate the methylation status of the proposed genes and their possible role in the tumor genesis and diagnosis of OSCC. MATERIALS AND METHODS: From sixty surgically treated and molecularly analyzed patients, we obtained three groups of bioptical materials: tumor, normal contralateral and healthy tissues...
July 29, 2018: Journal of Cranio-maxillo-facial Surgery
Gerhard K P Bittermann, Adrianus P de Ruiter, Arnold Jn Bittermann, Aebele B Mink van de Molen, Robert Jj van Es, Ron Koole, Antoine Jwp Rosenberg
OBJECTIVE: To evaluate midfacial growth and dental arch relationships in patients treated for bilateral cleft lip and palate (BCLP). MATERIALS AND METHODS: Data were collected from all patients with BCLP treated at our hospital between 2004 and 2014, with or without premaxillary osteotomy (PO). Dental casts for pre-secondary alveolar bone grafting with PO (SABG + PO) and end-point dental casts were analyzed using the BAURU yardstick scoring system. Pre-SABG + PO, post-SABG + PO, and end-point SABG + PO lateral cephalograms were analyzed...
July 26, 2018: Journal of Cranio-maxillo-facial Surgery
Nicolas Graillon, Nathalie Degardin, Jean Marc Foletti, Magali Seiler, Marine Alessandrini, Audrey Gallucci
BACKGROUND: Secondary alveolar bone grafting in patients with clefts lip and palate is usually performed with iliac crest bone harvesting, however using bone substitute allow to avoid harvesting morbidity. The purpose of our study was to assess if the use of a bioactive glass ceramic is an acceptable alternative to iliac crest bone harvesting in alveolar clefts treatment. METHODS: A prospective study including all patients who have benefited of alveolar grafting by GlassBONE™ (Noraker, France), a synthetic resorbable bioactive glass 45S5 ceramic was conducted...
July 26, 2018: Journal of Cranio-maxillo-facial Surgery
Anup Singh, Rajeev Kumar, David Victor Kumar Irugu, Rakesh Kumar, Prem Sagar
BACKGROUND: The arcuate eminence (AE) is a bony prominence on the middle fossa plate of the temporal bone, hypothesized to be variably associated with superior semicircular canal (SSC) relief, temporal lobe sulcus, and subjacent air cells. We present various morphometric parameters of the AE, as seen using a middle fossa approach. MATERIALS AND METHODS: The study used 18 formalin-preserved cadaveric human temporal bones. Various morphological and morphometric parameters pertaining to topographic orientation of the AE in relation to surrounding landmarks used in a middle mossa approach were noted, before and after microdissection of the AE under a Leica M320 F12 microscope, using otologic microdrills and suction irrigation...
July 25, 2018: Journal of Cranio-maxillo-facial Surgery
Niels Christian Pausch, Christoph Paul Kuhnt, Dirk Halama
INTRODUCTION: For treatment of lagophthalmos, metallic weight implants can be inserted in the upper eyelid to aid eyelid closure. Rigid and flexible implants are available. The objective of this study was to investigate the effect of implant type and patient variables on the survival of lid load implants. MATERIALS AND METHODS: Forty-four patients with lagophthalmos were recruited to undergo upper-eyelid weight implantation. The predictor variable was type of implant inserted (rigid or flexible)...
July 25, 2018: Journal of Cranio-maxillo-facial Surgery
Elizabeth T Niezen, Rudolf R M Bos, Baucke van Minnen, Uwe Eckelt, Frank Tavassol, Pieter U Dijkstra
PURPOSE: To explore differences in patient, fracture, accident and treatment characteristics between patients treated for a mandibular condyle fracture in the University Centres of Dresden and Groningen, as an explanation for differences treatment results. MATERIALS AND METHODS: Patients' fracture, accident and treatment characteristics were obtained from the medical records of Dresden and Groningen from January 1, 2008, to August 31, 2011, and were analysed using logistic regression analysis...
July 24, 2018: Journal of Cranio-maxillo-facial Surgery
Daniele Gibelli, Valentina Pucciarelli, Pasquale Poppa, Marco Cummaudo, Claudia Dolci, Cristina Cattaneo, Chiarella Sforza
Laser scanner devices are acquiring a growing importance in facial anatomy. Most studies have analysed facial scans obtained through two simultaneous captures, whereas the same result can be obtained by consecutive three-dimensional (3D) scans. However, this latter procedure has not yet been validated. Fourteen volunteers underwent face image capture through stereophotogrammetry (VECTRA M3) and three consecutive facial scans through a laser scanner (Konica Minolta Vi910). The concordance between 14 linear distances, 12 angles, facial surface area and volume measurements was verified by the Bland-Altman test and calculation of absolute and relative technical errors of measurement (TEM/rTEM)...
July 24, 2018: Journal of Cranio-maxillo-facial Surgery
Sven Holger Baum, Christopher Mohr
PURPOSE: The aim of this study was to examine the indications and results of autologous dermis-fat grafts in the reconstruction of maxillofacial soft-tissue defects. MATERIALS AND METHODS: A total of 93 patients with dermis-fat graft reconstruction due to a soft tissue defect in the head and neck region were enrolled in this retrospective clinical study between March 2002 and January 2017. They were classified into the subgroups 'parotid surgery', 'orbital surgery', and 'facial surgery'...
July 24, 2018: Journal of Cranio-maxillo-facial Surgery
Juho Suojanen, Sanna Järvinen, Karoliina Vm Kotaniemi, Justus Reunanen, Tuula Palotie, Patricia Stoor, Junnu Leikola
Individually designed osteotomies and milled or printed patient-specific osteosynthesis materials are rapidly becoming a standard in maxillofacial reconstructive surgery. The benefits of using patient-specific implants (PSIs) in orthognathic surgery are especially clear in complex cases, and for this reason they are rapidly becoming common practice. We have earlier reported the benefits related to the use of PSIs as reposition and fixation system in Le Fort I osteotomy. The aim of this study was to compare complications associated with fixation with PSIs (31 patients) versus conventional mini-plates (37 patients) in Le Fort I osteotomy...
July 23, 2018: Journal of Cranio-maxillo-facial Surgery
Jeroen Van Hevele, Erik Nout, Thomas Claeys, Joeri Meyns, Jan Scheerlinck, Constantinus Politis
This study evaluated the impact of class III correction by elastic traction on four miniplates and the failure rate of bone-anchored miniplates in nonsyndromic patients. A total of 218 patients (112 males and 106 females; average 11.4 years), treated by 38 orthodontists, received four miniplates (total 872 miniplates) from 2008 to 2016 at three maxillofacial centers in two countries. Factors affecting the success and failure of the miniplates were retrospectively examined and skeletal changes on cephalometric radiographs examined for 52 patients...
July 20, 2018: Journal of Cranio-maxillo-facial Surgery
Frank Halling, Paul Heymann, Thomas Ziebart, Andreas Neff
PURPOSE: To analyze the prescribing patterns of analgesics by dentists in Germany during an investigation period of five years in comparison to analgesic prescriptions by physicians and in relation to international prescribing data. MATERIALS AND METHODS: We analyzed nationwide data of all prescriptions of analgesics and antiphlogistics (except strong opioids) on the basis of the annual reports of the German statutory health insurances from 2012 to 2016. The types of analgesics, the number of prescriptions and the prescribed 'defined daily doses' (DDD) itemized by dentists and physicians were analyzed...
July 17, 2018: Journal of Cranio-maxillo-facial Surgery
Gesche Frohwitter, Stephan Wimmer, Carolin Goetz, Jochen Weitz, Michael Ulbig, Karsten U Kortuem, Julia Dangelmaier, Lucas Ritschl, Christian Doll, Oliver Ristow, Marco R Kesting, Steffen Koerdt
INTRODUCTION: Treatment decisions for fractures of the orbital floor are based on clinical appearance, ophthalmological examination, and computed tomography (CT) scans. In extensive fractures, decisions are easily made between conservative and surgical treatment. However, objective parameters are rare in inconclusive cases. MATERIALS AND METHODS: Our retrospective study included 106 patients with unilateral isolated orbital floor fractures. Correlations between preoperative ophthalmological examinations and specific CT parameters were performed...
July 11, 2018: Journal of Cranio-maxillo-facial Surgery
Andreas Naros, Annekathrin Brocks, Susanne Kluba, Siegmar Reinert, Michael Krimmel
PURPOSE: Cleft lip and/or palate (CLP) is the most common congenital craniofacial anomaly. Multiple operations, long-lasting supplementary treatments, as well as impaired functional and esthetic outcome might have a negative impact on patients' social-emotional functioning and self-esteem, resulting in a lower health-related quality of life (HRQoL). PATIENTS AND METHODS: This cross-sectional study aimed to evaluated CLP patients' HRQoL from preschool age (4 years) until adolescence (18 years) using the age-specific German KINDLR questionnaire...
July 11, 2018: Journal of Cranio-maxillo-facial Surgery
C Mourouzis, O Schoinohoriti, C Krasadakis, G Rallis
BACKGROUND: Maxillofacial fractures have been recognized as high risk trauma for concomitant cervical spine or spinal cord injury. OBJECTIVE: To investigate the incidence of concomitant cervical spine fractures (CSF) in patients with maxillofacial trauma and elucidate their relationship, guiding diagnosis and pointing their implications in maxillofacial trauma repair. MATERIAL AND METHODS: An analysis of 432 patients with maxillofacial fractures, treated at the Department of Oral and Maxillofacial Surgery of the "KAT" General Hospital of Attica during a three-year-long period, was conducted to investigate concomitant CSF...
July 11, 2018: Journal of Cranio-maxillo-facial Surgery
Stefanos Kanatsios, Omar Breik, George Dimitroulis
PURPOSE: The aim of this study was to determine the long-term outcomes following TMJ replacement using the stock Zimmer-Biomet TMJ device. In particular, investigated whether the titanium condylar implant and number of screws used to fixate it to the mandibular ramus had any impact on outcomes. METHODS: Subjects who underwent surgical implantation of a stock Zimmer-Biomet TMJ prosthesis were identified for this retrospective study. All patients received a titanium condylar component secured with four or five screws and ultra-high molecular weight polyethylene (UHMWPE) fossa with no metal reinforcement...
July 11, 2018: Journal of Cranio-maxillo-facial Surgery
Michael Schwaiger, Jürgen Wallner, Mauro Pau, Matthias Feichtinger, Tomislav Zrnc, Wolfgang Zemann, Philipp Metzler
The innovative TriLock Bridging Plate System (Medartis AG, Switzerland) was developed to reduce common complications related to conventional mandibular reconstruction plates. The novelties regarding the plating system concern the cross-strut structure in the centerpiece, the bendable side elements and the reduction of the plate's thickness to 2.0 mm 4 different models are available, which cover lateral and central segmental mandibular defects. The plating system has only been introduced at selected maxillofacial units so far and clinical assessment is still lacking...
July 7, 2018: Journal of Cranio-maxillo-facial Surgery
Camilla Baserga, Olindo Massarelli, Alessandro Remigio Bolzoni, Diego Sergio Rossi, Giada Anna Beltramini, Alessandro Baj, Aldo Bruno Giannì
PURPOSE: The osteogenic potential of vascularized periosteum has been described in a few cases in the literature, and many different factors have been pointed out as plausible. Our aim was to review the literature in order to give a complete overview of this topic and to report on our clinical experience. PATIENTS & METHODS: Our experience includes three patients who underwent maxillectomy and FFF reconstruction. A progressive reduction in mouth opening was noticed in the months after surgery, and CT scans showed calcified tissue around the pedicle...
July 5, 2018: Journal of Cranio-maxillo-facial Surgery
Xuzhuo Chen, Yexin Wang, Yi Mao, Zhihang Zhou, Jisi Zheng, Jinze Zhen, Yating Qiu, Shanyong Zhang, Haiyi Qin, Chi Yang
PURPOSE: This work aims to evaluate the biomechanical behavior of Chinese customized three-dimensional (3D)-printing total temporomandibular joint (TMJ) prostheses by means of finite element analysis. METHODS: A 3D model was established by Mimics 18.0, then output in a stereolithography (STL) format. Two models were established to investigate the strain behaviors of an intact mandible and a one-side implanted mandible respectively. Hypermesh and LS-DYNA software were used to establish computer-aided engineering finite element models...
July 5, 2018: Journal of Cranio-maxillo-facial Surgery
Eloá Cristina Passucci Ambrosio, Chiarella Sforza, Márcio De Menezes, Cleide Felício Carvalho Carrara, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira
This study aimed to use new three-dimensional (3D) anthropometric analyses to verify the post-surgical effects on the maxillary segments of children with unilateral cleft lip and palate. The sample was composed by digitized dental models of 60 children with unilateral complete cleft lip and alveolus (UCLA) and complete unilateral cleft lip and palate (UCLP). The impressions were taken before cheiloplasty (T1), after cheiloplasty (T2), and after palatoplasty (T3). The 3D anthropometric analyses of digitized dental casts were obtained through a specific software...
June 30, 2018: Journal of Cranio-maxillo-facial Surgery
Marieke M van de Meent, Sarina E C Pichardo, Myra F Rodrigues, Berit M Verbist, J P Richard van Merkesteyn
Diffuse sclerosing osteomyelitis (DSO) of the mandible is a poorly understood chronic disease. It is assumed to be a form of chronic osteomyelitis. Other forms of chronic osteomyelitis are chronic suppurative osteomyelitis (CSO) and osteoradionecrosis (ORN). This study aimed to investigate radiographic characteristics of DSO and compare these findings with the radiographic characteristics of CSO and ORN in order to radiographically distinguish these three diseases. In this retrospective study, 33 patients were clinically diagnosed with DSO (13), CSO (6), or ORN (14)...
June 30, 2018: Journal of Cranio-maxillo-facial Surgery
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