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Journal of Cranio-maxillo-facial Surgery

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https://www.readbyqxmd.com/read/29439841/investigation-of-cancer-associated-fibroblasts-and-p62-expression-in-oral-cancer-before-and-after-chemotherapy
#1
Lizhong Liang, Haiji Luo, Qifen He, Yingying You, Yunping Fan, Jun Liang
PURPOSE: The aim of this study is to investigate the expression of the autophagy protein p62 in oral squamous cell carcinoma (OSCC) cells before and after chemotherapy. We also detected cancer-associated fibroblasts (CAFs) in these OSCC samples to explore the roles of p62 and CAFs in chemotherapy. MATERIALS AND METHODS: Immunohistochemistry was used to analyze the expression of p62 and α-SMA in 26 paired OSCC samples before and after chemotherapy. The relationships between clinicopathological features, clinical outcome and the expression of these proteins were analyzed...
January 12, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29454604/cytotoxic-and-inflammatory-effects-of-alendronate-and-zolendronate-on-human-osteoblasts-gingival-fibroblasts-and-osteosarcoma-cells
#2
Yahya Açil, Mia Leena Arndt, Aydin Gülses, Henning Wieker, Hendrik Naujokat, Mustafa Ayna, Jörg Wiltfang
OBJECTIVE: The aim of this paper was to assess the effects of zoledronate (ZOL) and alendronate (FOS) on apoptotic behavior and gene expression of pro- and inflammatory cytokines of three cell types (human osteoblasts, human gingival fibroblasts and human osteogenic sarcoma cell lines) during a period of 4 weeks. MATERIAL AND METHODS: Cell viability and proliferation was assessed via cell proliferation test (MTT), fluorescence diacetate analysis (FDA). Expression of inflammatory cytokines was investigated by using polymerase chain reaction...
January 10, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29395994/alveolar-corticotomies-for-accelerated-orthodontics-a-systematic-review
#3
REVIEW
A P S Gil, O L Haas, I Méndez-Manjón, J Masiá-Gridilla, A Valls-Ontañón, F Hernández-Alfaro, R Guijarro-Martínez
INTRODUCTION: It has been suggested that alveolar corticotomies may accelerate tooth movement, broaden the scope of malocclusion types that can be treated orthodontically, decrease the need for extractions, and support long-term stability. Several techniques have been proposed, although the indications, ideal design and technical characteristics, potential complications, and objective clinician and patient satisfaction remain unclear. This systematic review aimed to provide scientific support to validate alveolar corticotomies as a reliable approach to accelerated orthodontics...
January 8, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29395993/a-worldwide-comparison-of-the-management-of-surgical-treatment-of-advanced-oral-cancer
#4
Katinka Kansy, Andreas Albert Mueller, Thomas Mücke, Friederike Koersgen, Klaus Dietrich Wolff, Hans-Florian Zeilhofer, Frank Hölzle, Winnie Pradel, Matthias Schneider, Andreas Kolk, Ralf Smeets, Julio Acero, Piet Haers, G E Ghali, Jürgen Hoffmann
INTRODUCTION: Microvascular surgery following tumor resection has become an important field of oral and maxillofacial surgery (OMFS). Following the results from management of T1/T2 floor-of-mouth and tongue squamous cell carcinoma (SCC) in German-speaking countries, Europe, and worldwide, this paper presents specific concepts for the management of resection and reconstruction of T3/T4 SCC of the maxillary and mandibular alveolar process and tongue. METHODS: The DÖSAK questionnaire was distributed in three different phases to a growing number of maxillofacial units worldwide...
January 8, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29398208/histo-morphologic-characteristics-of-intra-osseous-implants-of-we43-mg-alloys-with-and-without-heat-treatment-in-an-in%C3%A2-vivo-cranial-bone-sheep-model
#5
Andrea Torroni, Chongchen Xiang, Lukasz Witek, Eduardo D Rodriguez, Roberto L Flores, Nikhil Gupta, Paulo G Coelho
WE43 Mg alloy, composed of Mg, Yttrium, Rare Earth elements, and Zirconium, has proved to be a suitable candidate for production of resorbable osteosynthesis implants in both clinical and experimental settings. In a previous study we tested biocompatibility and degradation properties of untreated (as-cast) and artificially aged (T-5) WE43 Mg-alloys as subperiosteal implants on a maxillofacial sheep model. Both the alloy compositions showed excellent biocompatibility, however, with respect to degradation rate, the as-cast form showed increased degradability compared with the T-5...
January 4, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29395995/national-trends-in-tongue-reduction-surgery-for-macroglossia-in-children
#6
Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Andrew R Scott
OBJECTIVES: To examine the frequency of partial glossectomy performed for the indication of macroglossia in children within the United States, assessing for differences in rates of intervention across various demographics. To identify potential morbidities associated with partial glossectomy in this population and determine how such factors may influence length of stay and cost of admission following tongue reduction surgery. STUDY DESIGN: Retrospective cross-sectional study...
January 4, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29395991/effect-of-different-doses-and-durations-of-teriparatide-therapy-on%C3%A2-resolution-of-medication-related-osteonecrosis-of-the-jaw-a%C3%A2-randomized-controlled-preclinical-study-in-rats
#7
Mohammad Zandi, Arash Dehghan, Najmeh Zandipoor, Payam Amini, Shideh Doulati
OBJECTIVE: To evaluate the effects of different doses and durations of teriparatide therapy on MRONJ resolution in rats. SUBJECTS AND METHODS: A total of 120 rats that had been affected with MRONJ (after six weekly zoledronate injections and tooth extraction) were randomly divided into eight subgroups: 2, 10, and 20 μg/kg/day teriparatide were administered to L4, M4, and H4 for 4 weeks, and to L8, M8, and H8 for 8 weeks, respectively. C4 and C8 received saline for 4 and 8 weeks, respectively...
December 30, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29426585/location-of-the-euryon-in-scaphocephalic-vs-non-scaphocephalic-controls-a-novel-assessment-of-cranial-vault-remodeling-outcomes
#8
Ryan Winters, Sherard A Tatum
We describe a novel measurement of cranial morphology in pre- and post-operative scaphocephalic patients to complement the cephalic index. This will better describe restoration of normal skull and head shape, further defining the nuances of the corrected skull. In this retrospective comparative study the location of the euryon on the skull was statistically significantly different in preoperative scaphocephalic patients versus non-scaphocephalic controls. This difference was resolved with surgical cranial vault remodeling, indicating restoration of a normal skull profile...
December 29, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29395992/bioabsorbable-plates-versus-metal-miniplate-systems-for-use-in-endoscope-assisted-open-reduction-and-internal-fixation-of-mandibular-subcondylar-fractures
#9
Dong-Yul Kim, Iel-Yong Sung, Yeong-Cheol Cho, Eun-Ji Park, Jang-Ho Son
PURPOSE: To compare bioabsorbable plates with metal miniplate systems for use in endoscope-assisted open reduction and internal fixation (EAORIF) of mandibular subcondylar fractures. MATERIALS AND METHODS: This retrospective cohort study included patients with mandibular subcondylar fractures treated with EAORIF using bioabsorbable unsintered hydroxyapatite/poly l-lactide composite plates or titanium miniplate systems. The outcome variables included preoperative fracture conditions, postoperative stability during fracture healing, and complications during the follow-up period...
December 29, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29317142/volumetric-mandibular-change-after-angle-ostectomy-and-outer-cortex-grinding
#10
Jingyi Zhao, Guodong Song, Xianlei Zong, Xiaonan Yang, Le Du, Xiaoshuang Guo, Chenzhi Lai, Zuoliang Qi, Xiaolei Jin
BACKGROUND: Mandibular angle ostectomy is one of the most common surgical procedures for facial contouring in Asian women. However, some patients complain about mandibular angle hypertrophy recurrence after surgery. The present study evaluated volumetric change of the mandible after angle ostectomy and outer cortex grinding. METHODS: Twenty-four patients who underwent bilateral mandibular angle ostectomy and outer cortex grinding from 2013 to 2016 were enrolled...
December 29, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29311017/reanimation-of-the-paralyzed-lids-by-cross-face-nerve-graft-and-platysma-transfer
#11
Federico Biglioli, Matteo Zago, Fabiana Allevi, Daniela Ciprandi, Giovanni Dell'Aversana Orabona, Valentina Pucciarelli, Dimitri Rabbiosi, Ilaria Pacifici, Filippo Tarabbia, Chiarella Sforza
Alterations of facial muscles may critically humper patients' quality of life. One of the worst conditions is the reduction or abolition of eye blinking. To prevent these adverse effects, surgical rehabilitation of eyelid function is the current treatment choice. In the present paper, we present a modification of the technique devised by Nassif to recover lids from long-standing paralysis. In our modification, the upper lid is rehabilitated by a platisma graft innervated by the contralateral facial nerve branches using a cross-face sural nerve graft...
December 27, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29325889/early-cell-response-of-osteogenic-cells-on-differently-modified-implant-surfaces-sequences-of-cell-proliferation-adherence-and-differentiation
#12
Sebastian Blatt, Andreas Max Pabst, Eik Schiegnitz, Marco Hosang, Thomas Ziebart, Christian Walter, Bilal Al-Nawas, Marcus Oliver Klein
OBJECTIVES: Osseointegration of dental implants is a crucial prerequisite for long-term survival. Therefore, surface modifications are needed to interact with the extracellular environment and to trigger osteogenic cell responses such as cell proliferation, adherence, and differentiation. The purpose of this study was to investigate different surface modifications in vitro over 2 weeks. MATERIALS AND METHODS: Commercially available cells from a human osteogenic cell line (HHOB-c) were cultivated on the following surfaces: titanium with smooth surfaces (polished titanium (P), machined titanium (M), polyetheretherketone (Peek)), titanium with rough and hydrophilised surfaces (acid etched titanium (A), sandblasted acid etched titanium (SA and SA2), sandblasted acid etched hydrophilised (SAH), titanium plasma painted titanium (TPS)), titanium with calcium phosphate-containing surfaces (titanium plasma painted calcium phosphate modified titanium (TPS-CaP), sandblasted calcium phosphate modified titanium (S-CaP), sandblasted acid etched calcium phosphate modified titanium (SA-CaP)), and zirconium-oxide (yttrium amplified zirconium (Z), yttrium amplified Ca2+ delivering zirconium (Z-Ca))...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29325888/computed-exophthalmometry-is-an-accurate-and-reproducible-method-for-the-measuring-of-eyeballs-protrusion
#13
Daria S Afanasyeva, Marina B Gushchina, Maxim Y Gerasimov, Sergey A Borzenok
PURPOSE: The aim of this study was to assess reproducibility of the repeated measurements from proposed computed exophthalmometry and to make a comparison with the Hertel exophthalmometer. METHODS: Computed tomography scans of patients with pathological (group 1) and intact orbits (group 2) were included in this retrospective study. In both groups, a single investigator measured a difference of eyeballs' protrusion using the proposed method of computed exophthalmometry...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29311022/three-dimensional-titanium-miniplates-for-fixation-of-subcondylar-mandibular-fractures-comparison-of-five-designs-using-patient-specific-finite-element-analysis
#14
Mhd Hassan Albogha, Yoshihide Mori, Ichiro Takahashi
PURPOSE: The purpose of the current study is to compare the performance of five designs of three-dimensional titanium miniplates (lambda, strut, delta, rhombic and trapezoid) for fixation of subcondylar mandibular fracture. MATERIALS AND METHODS: Three-dimensional models were constructed for the five miniplates with their screws and integrated into a virtually fractured mandible that was derived from a computed tomographic image of living human. Patient-specific finite element models were analyzed to compare the performances of the miniplates...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29311021/squamous-odontogenic-tumor-and-squamous-odontogenic-tumor-like-proliferations-in-odontogenic-cysts-an-updated-analysis-of-170-cases-reported-in-the-literature
#15
REVIEW
Bruno Ramos Chrcanovic, Ricardo Santiago Gomez
PURPOSE: To integrate the available data published on squamous odontogenic tumors (SOT) and squamous odontogenic tumor-like proliferations in odontogenic cysts (SOT-LPOC) into a comprehensive analysis of their clinical/radiologic features. MATERIALS AND METHODS: An electronic search was undertaken in January 2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm a definite diagnosis. RESULTS: A total of 74 publications reporting 110 SOTs (102 central, 8 peripheral) and 60 SOT-LPOC were included...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29311019/the-ideal-ear-position-in-caucasian-females
#16
P Niclas Broer, Aung Thiha, Denis Ehrl, Sammy Sinno, Sabrina Juran, Caroline Szpalski, Reuben Ng, Milomir Ninkovic, Lukas Prantl, Paul I Heidekrueger
PURPOSE: Ear position contributes significantly to facial appearance. However, while objective measurements remain the foundation for esthetic evaluations, little is known about how an ear should ideally be positioned regarding its rotational axis. This study aimed to further evaluate whether there exists a universally applicable ideal ear axis, and how sociodemographic factors impact such preferences. MATERIALS AND METHODS: An interactive online survey was designed, enabling participants to change the axis of a female model's ear in terms of its forward and backward rotation...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29398209/comparison-of-preseptal-and-retroseptal-transconjunctival-approaches-in-patients-with-isolated-fractures-of-the-orbital-floor
#17
Salem Barcic, Michael Blumer, Harald Essig, Paul Schumann, Daniel B Wiedemeier, Martin Rücker, Thomas Gander
Transconjunctival approach has become a standard procedure to access fractures of orbit and the infraorbital rim. The transconjunctival incision can be performed pre- or retroseptally. Both approaches have been described combined with modifications such as transcaruncular or detachment of the lateral canthus for wider exposure of the orbital walls and rim. Particularly concerning aesthetics, the transconjunctival approach shows advantages compared to the transcutaneous incisions, such as the transciliary and infraorbital access...
December 24, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29311018/melanoma-associated-antigen-a11-reduces-erlotinib-and-afatinib-efficacy-in-head-and-neck-cancer
#18
Stefan Hartmann, Leonie Zwick, Katja Maurus, Andreas R Fuchs, Roman C Brands, Axel Seher, Alexander C Kübler, Urs D A Müller-Richter
Melanoma-associated antigen A (MAGE-A) proteins are members of the cancer/testis antigens (CTA), and the expression of these proteins is almost exclusively limited to malignant cells, making them an attractive treatment target. MAGE-A expression is correlated with poor overall survival in several cancers, including head and neck squamous cell carcinoma (HNSCC). Among others, MAGE-A11 was found to be associated with resistance to different antineoplastic and targeted compounds, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs)...
December 24, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29325886/comparison-analysis-of-orbital-shape-and-volume-in-unilateral-fractured-orbits
#19
Johanna Nilsson, Johan Nysjö, Anders-Petter Carlsson, Andreas Thor
Facial fractures often result in changes of the orbital volume. These changes can be measured in three-dimensional (3D) computed tomography (CT) scans for preoperative planning and postoperative evaluation. The aim of this study was to analyze the orbital volume and shape before and after surgical treatment of unilateral orbital fractures using semi-automatic image segmentation and registration techniques. The orbital volume in 21 patients was assessed by a semi-automatic model-based segmentation method. The fractured orbit was compared relative to the contralateral orbit...
December 21, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29311020/is-the-routine-practice-of-antibiotic-prescription-and-microbial-culture-and-antibiotic-sensitivity-testing-justified-in-primary-maxillofacial-space-infection-patients-a-prospective-randomized-clinical-study
#20
Saroj Kumari, Sujata Mohanty, Pankaj Sharma, Jitender Dabas, Sanchaita Kohli, Cathrine Diana
PURPOSE: The purpose of this prospective, randomized, comparative clinical study was to compare treatment outcome of removal of foci and incision and drainage, with or without oral antibiotic therapy, in the management of single primary maxillofacial space infection with a known focus. MATERIALS AND METHODS: A total of 40 patients with single primary maxillofacial space infection with a known infectious focus were divided into two groups, one treated with incision and drainage only, and the other with incision and drainage along with oral antibiotics...
December 20, 2017: Journal of Cranio-maxillo-facial Surgery
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