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https://www.readbyqxmd.com/read/28338667/primary-photodynamic-therapy-with-verteporfin-for-small-pigmented-posterior-pole-choroidal-melanoma
#1
I D Fabian, A W Stacey, V Papastefanou, L Al Harby, A K Arora, M S Sagoo, V M L Cohen
PurposeThe purpose of the study was to investigate the outcomes of primary photodynamic therapy (PDT) for small pigmented posterior pole choroidal melanoma.Patients and methodsProspective interventional consecutive case series of 15 patients with small pigmented posterior pole choroidal melanoma, who were treated with three sessions of PDT and followed-up thereafter. Risk factors for failure were assessed and outcome measures at presentation were compared to those at last follow-up visit.ResultsTumor control was achieved in 12 (80%) patients in a median follow-up time of 15 months (mean 14, range 8-18)...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28338666/the-association-of-maternal-factors-with-epibulbar-dermoid-of-newborn-a-retrospective-matched-case-control-study
#2
S Wu, Y Fan, D Wu, J Hong, J Xu
PurposeTo determine the association of maternal factors and exposure during pregnancy with the incidence in newborns of epibulbar dermoid (ED), a congenital ocular surface benign tumor.Patients and methodsThis is a retrospective, paired case-control study in which 121 children with ED (case group) and 121 children without ED (control group) were recruited. Questionnaire-based interviews with mothers of participants were performed and maternal medical records during pregnancy were reviewed. The questionnaire investigated basic information, personal history, environmental exposure, exposure to maternal diseases, symptoms and corresponding medical treatments during pregnancy, and parental socioeconomic status...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28338665/vessel-diameter-study-intravitreal-vs-posterior-subtenon-triamcinolone-acetonide-injection-for-diabetic-macular-edema
#3
M M Kurt, O Çekiç, Ç Akpolat, M Aslankurt, M Elçioğlu
PurposeTo detect and compare the vessel diameter effect of intravitreal vs subtenon injection of triamcinolone for diabetic macular edema (DME).MethodsSixty patients with DME who underwent triamcinolone injection either intravitreally (N=30) or under the tenon capsule (N=30) were included. Non-injected fellow eyes served as control. The main outcome measures were central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), and artery-vein ratio (AVR).ResultsIn the intravitreal group, pre-injection mean CRAE (147...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28338664/characteristics-of-non-vitreoretinal-ocular-injury-in-child-maltreatment-a-systematic-review
#4
T Betts, S Ahmed, S Maguire, P Watts
PurposeTo identify the spectrum of non-vitreoretinal ocular injury due to child maltreatment.MethodsAll language search of MEDLINE, PsychINFO, EMBASE, AMED, Web of Science, and CINAHL databases, 1950-2015, was conducted. INCLUSION CRITERIA: explicit confirmation of injury aetiology, age <18 years, examination conducted by an ophthalmologist. Exclusion: post-mortem data, organic diseases, review articles. Standardised critical appraisal and narrative synthesis was conducted of included publications by two independent reviewers...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28338663/prevalence-and-associated-factors-of-blepharoptosis-in-korean-adult-population-the-korea-national-health-and-nutrition-examination-survey-2008-2011
#5
M H Kim, J Cho, D Zhao, K I Woo, Y-D Kim, S Kim, S W Yang
PurposeThis study aimed to evaluate the prevalence and associated factors of involutional blepharoptosis in a nationwide representative sample in Korea.MethodsCross-sectional study 20 941 Korean men and women 40 years of age and older who participated in last 2 years (2008 and 2009) of the 4th wave of the Korean National Health and Nutrition Examination Survey (KNHANES) IV and the first 2 years (2010 and 2011) of KNHANES V. Ocular examinations were performed by ophthalmologists trained in procedure and grading methods, and blepharoptosis was defined as a marginal reflex distance <2 mm on either eye...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28304389/manifestation-and-grading-of-ocular-involvement-in-patients-with-tessier-number-10-clefts
#6
C Shao, W Lu, J Li, J Chen, Q Yao, X Fan, Y Fu
PurposeThe objective of this study is to evaluate and grade the extent and severity of ocular involvement in Tessier number 10 cleft.Patients and methodsA retrospective, noncomparative, interventional case series was conducted between January 2006 and December 2015. Clinical data were reviewed from 59 patients (85 eyes) with Tessier number 10 clefts. Detailed medical history and ophthalmic examination of patients with a confirmed diagnosis of Tessier number 10 cleft were recorded on an itemized data collection form...
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28304388/pirfenidone-inhibits-post-traumatic-proliferative-vitreoretinopathy
#7
B N M K Khanum, R Guha, V P Sur, S Nandi, S K Basak, A Konar, S Hazra
PurposeThe purpose of the study was to evaluate the efficacy and safety of intravitreal pirfenidone for inhibition of proliferative vitreoretinopathy (PVR) in a model of penetrating ocular injury.Patients and methodsPenetrating trauma was induced on the retina of rabbit and treated either with 0.1 ml of phosphate-buffered saline (PBS) or 0.1 ml of 0.5% pirfenidone, and development of PVR was evaluated clinically and graded after 1 month. Histopathology and immunohistochemistry with transforming growth factor beta (TGFβ), alpha smooth muscle actin (αSMA), and collagen-1 were performed to assess the fibrotic changes...
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28304387/extubation-following-dacryocystorhinostomy-an-alternative-technique
#8
M Galea, F Shams, E Saxby, E Newcott, V Chadha, E Kemp
No abstract text is available yet for this article.
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28304386/effect-of-pregnancy-in-myopia-progression-the-sun-cohort
#9
A Fernández-Montero, M Bes-Rastrollo, J Moreno-Montañés, L Moreno-Galarraga, M Á Martínez-González
PurposePrevious studies have suggested that pregnancy may induce myopia progression. However, no longitudinal study with a large sample size and long-term follow-up has assessed this association. Our objective was to investigate whether pregnancy was related to mid- or long-term myopic refraction changes.Patients and methodsA prospective study was conducted in a Mediterranean cohort. The study included 10 401 women (20-50 years old) from the SUN Project. SUN project is a multipurpose, prospective, and dynamic cohort of university graduates conducted in Spain...
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28304385/local-ocular-surface-parameters-in-patients-with-systemic-celiac-disease
#10
M M Uzel, M Citirik, M Kekilli, P Cicek
PurposeThis was a collaborative study from the Ophthalmology and Gastroenterology departments of a tertiary care hospital, designed to investigate the local ocular surface parameters in patients with celiac disease (CD).MethodsFifty-six eyes of 28 patients with CD and 58 eyes of 29 healthy adult subjects serving as controls were evaluated. The Schirmer test, tear-film break-up time, and conjunctival impression cytology were performed in addition to a complete ophthalmological examination. Impression cytology specimens of each group were graded and scored in the range 0-3...
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28304384/the-contribution-of-ophthalmology-journals-to-undergraduate-medical-education
#11
I Barai, V A Nowak
No abstract text is available yet for this article.
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28304383/treatment-patterns-of-ranibizumab-intravitreal-injection-and-dexamethasone-intravitreal-implant-for-retinal-vein-occlusion-in-the-usa
#12
D Călugăru, M Călugăru
No abstract text is available yet for this article.
March 17, 2017: Eye
https://www.readbyqxmd.com/read/28282068/surgical-treatment-and-optical-coherence-tomographic-evaluation-for-accidental-laser-induced-full-thickness-macular-holes
#13
Y Qi, Y Wang, Q You, F Tsai, W Liu
PurposeTo report OCT appearance and surgical outcomes of full-thickness macular holes (MHs) accidentally caused by laser devices.Patients and methodsThis retrospective case series included 11 eyes of 11 patients with laser-induced MHs treated by pars plana vitrectomy, internal limiting membrane (ILM) peeling, and gas or silicone oil tamponade. Evaluations included a full ophthalmic examination, macular spectral-domain optical coherence tomography (SD-OCT), and fundus photography. Main outcome measures is MH closure and final visual acuity; the secondary outcome was the changes of retinal pigment epithelium and photoreceptor layer evaluated by sequential post-operative SD-OCT images...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282067/evaluation-of-dry-eye-and-meibomian-gland-dysfunction-with-meibography-in-vitiligo
#14
M Palamar, P Kiyat, I Ertam, A Yagci
PurposeTo evaluate the dry eye and meibomian gland dysfunction (MGD) of vitiligo patients with meibography.MethodsTwenty eyes of 20 vitiligo patients (Group 1) and 20 eyes of 20 healthy individuals (Group 2) were enrolled. All subjects had undergone a comprehensive ophthalmic examination including corneal and conjunctival fluorescein staining (Oxford scale scoring), tear film break-up time (T-BUT), Schirmer 1 test, Ocular Surface Disease Index (OSDI) score assessment, and upper and lower eyelid meibography using infrared captures of a biomicroscope (Topcon, SL-D701, IJssel, The Netherlands)...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282066/medically-unexplained-visual-loss-in-children-and-young-people-an-observational-single-site-study-of-incidence-and-outcomes
#15
M C Daniel, A Coughtrey, I Heyman, A H Dahlmann-Noor
PurposeTo determine the incidence of medically unexplained visual loss (MUVL) in children in an open access children's eye casualty.Patients and methodsWe collated demographic and clinical data of consecutive patients younger than 16 years who presented to the children's eye casualty at Moorfields Eye Hospital over a 12-month period and were diagnosed with MUVL or suspected MUVL. We reviewed the clinical records at least 3 months after initial presentation. We calculated the incidence using the number of 'new patient' attendances over the same period as denominator (n=2397)...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282065/fundus-autofluorescence-imaging-systematic-review-of-test-accuracy-for-the-diagnosis-and-monitoring-of-retinal-conditions
#16
REVIEW
G K Frampton, N Kalita, L Payne, J L Colquitt, E Loveman, S M Downes, A J Lotery
We conducted a systematic review of the accuracy of fundus autofluorescence (FAF) imaging for diagnosing and monitoring retinal conditions. Searches in November 2014 identified English language references. Sources included MEDLINE, EMBASE, the Cochrane Library, Web of Science, and MEDION databases; reference lists of retrieved studies; and internet pages of relevant organisations, meetings, and trial registries. For inclusion, studies had to report FAF imaging accuracy quantitatively. Studies were critically appraised using QUADAS risk of bias criteria...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282064/predicting-the-risk-of-parafoveal-scotoma-in-myopic-normal-tension-glaucoma-role-of-optic-disc-tilt-and-rotation
#17
M S Sung, H Heo, Y S Ji, S W Park
PurposeThe purpose of the study was to evaluate the factors associated with development of parafoveal scotoma in early myopic normal tension glaucoma (NTG).Patients and methodsNinety-nine myopic NTG patients with mean deviation (MD) >-6.0 decibels (dB) were enrolled. Parafoveal scotoma was defined as a visual field (VF) defect within 10° of fixation with at least one point at P<1% lying at the four innermost central points. Systemic factors, optic disc characteristics including tilt ratio, rotation degree, β-zone parapapillary atrophy, disc hemorrhage, and peripapillary retinal nerve fiber layer and macular ganglion cell-inner plexiform layer (mGCIPL) thickness parameters using optical coherence tomography were evaluated...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282063/lower-urinary-cotinine-level-is-associated-with-a-trend-toward-more-myopic-refractive-errors-in-korean-adolescents
#18
G E Nam, B E Hwang, Y-C Lee, J-S Paik, S-W Yang, Y-H Chun, K Han, Y G Park, S H Park
PurposeTo investigate the association between urinary cotinine levels as an objective biological marker for exposure to nicotine and refractive status.Patients and methodsThis cross-sectional study analyzed data from the Korea National Health and Nutrition Examination Survey between 2008 and 2011. A total of 1139 Korean adolescents aged 12-18 years were enrolled. Urinary cotinine concentrations and other potential risk factors for myopia were examined. Correlation analyses and multivariate regression analysis were performed to investigate the association between urinary cotinine level and refractive error...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282062/prevalence-of-age-related-macular-degeneration-in-an-elderly-uk-caucasian-population-the-bridlington-eye-assessment-project-a-cross-sectional-study
#19
C Wilde, A Poostchi, R L Mehta, H K MacNab, J G Hillman, S A Vernon, W M Amoaku
ImportanceThere is paucity of data on prevalence and disease asymmetry of age-related macular degeneration (AMD), particularly the earlier stages, in the UK population.Objective and PurposeTo determine the prevalence of age-related macular degeneration in an elderly Caucasian UK population.DesignCross-sectional population study, 2002-2006.ParticipantsResidents in the study area of Bridlington aged 65 years and older.MethodsFull-ophthalmic examination was undertaken in 3549 participants, of eligible 6319 Caucasian population (response rate of 56%)...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28282061/hydroxychloroquine-retinopathy
#20
REVIEW
I H Yusuf, S Sharma, R Luqmani, S M Downes
Hydroxychloroquine (HCQ; Plaquenil) is used increasingly in the management of a variety of autoimmune disorders, with well established roles in dermatology and rheumatology and emerging roles in oncology. Hydroxychloroquine has demonstrated a survival benefit in patients with systemic lupus erythematosus; some clinicians advocate its use in all such patients. However, Hydroxychloroquine and chloroquine (CQ) have been associated with irreversible visual loss due to retinal toxicity. Hydroxychloroquine retinal toxicity is far more common than previously considered; an overall prevalence of 7...
March 10, 2017: Eye
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