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Epidemiology and Infection

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https://www.readbyqxmd.com/read/28100289/hepatitis-b-virus-in-drug-users-in-france-prevalence-and-vaccination-history-anrs-coquelicot-survey-2011-2013
#1
C Brouard, J Pillonel, P Sogni, A Chollet, J V Lazarus, X Pascal, F Barin, M Jauffret-Roustide
People who use drugs (PWUD) are a key population for hepatitis B virus (HBV) vaccination and screening. We aimed to estimate the seroprevalence of HBs antigen (HBsAg) and self-reported HBV vaccination history in French PWUD attending harm reduction centres using data from the ANRS-Coquelicot multicentre survey conducted in 2011-2013 in 1718 PWUD. Self-fingerprick blood samples were collected on dried blood spots to detect the presence of HBsAg. HBsAg seroprevalence was estimated at 1·4% [95% confidence interval (CI) 0·8-2·5]...
January 19, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28100286/disease-burden-of-hepatitis-e-in-a-rural-population-in-china-a-community-based-survey
#2
H Jiang, S Huang, Y Zhao, Y Wang, C Yang, J Cai, Z Wang, J Zhang, X Zhang, H Jin
This study aimed to estimate the disease burden of hepatitis E in a rural region in China. A total of 489 hepatitis E cases were reported according to a community-based survey in an active hepatitis surveillance system between 2008 and 2015, the questionnaire and record-review methods were constructed to evaluate the economic and health burden of hepatitis E virus infections from societal perspectives. All costs were converted to US$ in 2015. The age-standardized cumulative incidence rate was 107·9/100 000, and the median age-standardized annual incidence rate was 16·5/100 000...
January 19, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28095930/quantitative-risk-assessment-of-the-introduction-of-rabies-into-japan-through-the-importation-of-dogs-and-cats-worldwide
#3
N C L Kwan, K Sugiura, Y Hosoi, A Yamada, E L Snary
Japan has been free from rabies since 1958. A strict import regimen has been adopted since 2004 consisting of identification of an animal with microchip, two-time rabies vaccination, neutralizing antibody titration test and a waiting period of 180 days. The present study aims to quantitatively assess the risk of rabies introduction into Japan through the international importation of dogs and cats and hence provide evidence-based recommendations to strengthen the current rabies prevention system. A stochastic scenario tree model was developed and simulations were run using @RISK...
January 18, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28095926/epidemiology-of-parainfluenza-infection-in-england-and-wales-1998-2013-any-evidence-of-change
#4
H Zhao, R J Harris, J Ellis, M Donati, R G Pebody
Human parainfluenza virus (HPIV) infections are one of the commonest causes of upper and lower respiratory tract infections. In order to determine if there have been any recent changes in HPIV epidemiology in England and Wales, laboratory surveillance data between 1998 and 2013 were analysed. The UK national laboratory surveillance database, LabBase, and the newly established laboratory-based virological surveillance system, the Respiratory DataMart System (RDMS), were used. Descriptive analysis was performed to examine the distribution of cases by year, age, sex and serotype, and to examine the overall temporal trend using the χ 2 test...
January 18, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091347/changes-in-the-seroprevalence-of-cysticercosis-in-suspected-patients-in-chandigarh-india-between-1998-and-2014-analysis-of-17-years-of-data
#5
L J Robertson, H Joshi, K S Utaaker, A Kumar, S Chaudhary, K Goyal, R Sehgal
Changes in seroprevalence of cysticercosis diagnosed in Chandigarh, India between 1998 and 2014 were investigated by extraction and analysis of data from records held at the Postgraduate Institute of Medical Education and Research in Chandigarh. Among the total number of samples for which cysticercosis had been suspected during this period (N = 9650), 1716 (17·8%) were seropositive. Adults were more likely to be seropositive than children, and women were more likely to be seropositive than men. In addition to there being fewer patients with suspicion of cysticercosis over the data analysis period, the proportion of patients seropositive also reduced significantly...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091341/correlation-between-infectious-disease-and-soil-radiation-in-japan-an-exploratory-study-using-national-sentinel-surveillance-data
#6
S Inaida, T Tsuda, S Matsuno
We investigated the relationship between epidemics and soil radiation through an exploratory study using sentinel surveillance data (individuals aged <20 years) during the last three epidemic seasons of influenza and norovirus in Japan. We used a spatial analysis method of a geographical information system (GIS). We mapped the epidemic spreading patterns from sentinel incidence rates. We calculated the average soil radiation [dm (μGy/h)] for each sentinel site using data on uranium, thorium, and potassium oxide in the soil and examined the incidence rate in units of 0·01 μGy/h...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091339/association-of-cigarette-smoking-with-a-past-history-and-incidence-of-herpes-zoster-in-the-general-japanese-population-the-shez-study
#7
J Ban, Y Takao, Y Okuno, Y Mori, H Asada, K Yamanishi, H Iso
Few studies have examined the impact of cigarette smoking on the risk for herpes zoster. The Shozu Herpes Zoster (SHEZ) Study is a community-based prospective cohort study over 3 years in Japan aiming to clarify the incidence and predictive and immunological factors for herpes zoster. We investigated the associations of smoking status with past history and incidence of herpes zoster. A total of 12 351 participants provided valid information on smoking status and past history of herpes zoster at baseline survey...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091338/molecular-epidemiological-analysis-to-assess-the-influence-of-pet-ownership-in-the-biodiversity-of-staphylococcus-aureus-and-mrsa-in-dog-and-non-dog-owning-healthy-households
#8
J C VAN Balen, T Landers, E Nutt, A Dent, A E Hoet
It has been suggested that zoonotic transmission of Staphylococcus aureus (SA) and methicillin-resistant S. aureus (MRSA) can occur between owners and their pets within the same household. However, the influence that pet-ownership could have in the biodiversity of SA/MRSA strains circulating among owners is not fully understood. The objective of this study was to perform a molecular epidemiological analysis to evaluate and compare the biodiversity of SA/MRSA strains in dog-owning and non-dog-owning healthy households within the same community...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091337/assessing-the-social-and-environmental-determinants-of-pertussis-epidemics-in-queensland-australia-a-bayesian-spatio-temporal-analysis
#9
X Huang, S Lambert, C Lau, R J Soares Magalhaes, J Marquess, M Rajmokan, G Milinovich, W Hu
Pertussis epidemics have displayed substantial spatial heterogeneity in countries with high socioeconomic conditions and high vaccine coverage. This study aims to investigate the relationship between pertussis risk and socio-environmental factors on the spatio-temporal variation underlying pertussis infection. We obtained daily case numbers of pertussis notifications from Queensland Health, Australia by postal area, for the period January 2006 to December 2012. A Bayesian spatio-temporal model was used to quantify the relationship between monthly pertussis incidence and socio-environmental factors...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091336/who-are-the-patients-that-default-tuberculosis-treatment-space-matters
#10
C Nunes, R Duarte, A M Veiga, B Taylor
The goals of this article are: (i) to understand how individual characteristics affect the likelihood of patients defaulting their pulmonary tuberculosis (PTB) treatment regimens; (ii) to quantify the predictive capacity of these risk factors; and (iii) to quantify and map spatial variation in the risk of defaulting. We used logistic regression models and generalized additive models with a spatial component to determine the odds of default across continental Portugal. We focused on new PTB cases, diagnosed between 2000 and 2013, and included some individual information (sex, age, residence area, alcohol abuse, intravenous drug use, homelessness, HIV, imprisonment status)...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28091335/high-prevalence-of-hpv-infection-in-the-remote-villages-of-french-guiana-an-epidemiological-study
#11
A Adenis, V Dufit, M Douine, F Corlin, G Ayhan, F Najioullah, V Molinie, P Brousse, G Carles, V Lacoste, R Cesaire, M Nacher
Cervical cancer is the second most frequent cancer in women in French Guiana. Studies have shown that populations living in the remote areas of the interior have early sexual debut and that multiple sexual partnerships are common. The objective of the present study was thus to determine the prevalence of human papillomavirus (HPV) infection in these areas. A study was conducted in women aged 20-65 years with previous sexual activity. Women were included on a voluntary basis after using local media and leaders to inform them of the visit of the team...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065212/hospital-acquired-listeriosis-linked-to-a-persistently-contaminated-milkshake-machine
#12
E Mazengia, V Kawakami, K Rietberg, M Kay, P Wyman, C Skilton, A Aberra, J Boonyaratanakornkit, A P Limaye, S A Pergam, E Whimbey, R J Olsen-Scribner, J S Duchin
One case of hospital-acquired listeriosis was linked to milkshakes produced in a commercial-grade shake freezer machine. This machine was found to be contaminated with a strain of Listeria monocytogenes epidemiologically and molecularly linked to a contaminated pasteurized, dairy-based ice cream product at the same hospital a year earlier, despite repeated cleaning and sanitizing. Healthcare facilities should be aware of the potential for prolonged Listeria contamination of food service equipment. In addition, healthcare providers should consider counselling persons who have an increased risk for Listeria infections regarding foods that have caused Listeria infections...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065210/prevalence-of-tuberculosis-infection-in-healthcare-workers-of-the-public-hospital-network-in-medell%C3%A3-n-colombia-a-bayesian-approach
#13
J Ochoa, A L León, I C Ramírez, C M Lopera, E Bernal, M P Arbeláez
A latent tuberculosis infection (LTBI) prevalence survey was conducted using tuberculin skin test (TST) and Quantiferon test (QFT) in 1218 healthcare workers (HCWs) in Medellín, Colombia. In order to improve the prevalence estimates, a latent class model was built using a Bayesian approach with informative priors on the sensitivity and specificity of the TST. The proportion of concordant results (TST+,QFT+) was 41% and the discordant results contributed 27%. The marginal estimate of the prevalence P(LTBI+) was 62·1% [95% credible interval (CrI) 53·0-68·2]...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065205/australia-s-national-notifiable-diseases-surveillance-system-1991-2011-expanding-adapting-and-improving
#14
K B Gibney, A C Cheng, R Hall, K Leder
We reviewed key attributes (flexibility, data quality and timeliness) of Australia's National Notifiable Diseases Surveillance System (NNDSS) over its first 21 years. Cases notified to NNDSS from 1991 to 2011 were examined by jurisdiction (six states and two territories) and sub-period to describe changes in the number of notifiable diseases, proportion of cases diagnosed using PCR tests, data quality (focusing on data completeness), and notification delays. The number of notifiable diseases increased from 37 to 65...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065204/risk-factors-for-pertussis-in-adults-and-teenagers-in-england
#15
A Wensley, G J Hughes, H Campbell, G Amirthalingam, N Andrews, N Young, L Coole
Pertussis is a vaccine-preventable respiratory infection caused by Bordetella pertussis which can be fatal in infants. Although high vaccine coverage led to prolonged disease control in England, a national outbreak of pertussis in 2011 led to the largest increase in over two decades, including a marked increase in cases aged ⩾15 years. A case-control study in four regions of England was undertaken to investigate risk factors for pertussis in adolescents and adults, specifically employment type and professional and household contact with children...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065202/using-positive-deviance-in-the-prevention-and-control-of-mrsa-infections-in-a-colombian-hospital-a-time-series-analysis
#16
N M Olarte Escobar, I A Valderrama Márquez, J Avila Quiroga, T Goretty Trujillo, F González, M I Garzón Aguilar, J Escobar-Pérez
Positive Deviance (PD) is a process to achieve a social and cultural change. This strategy has been used for the control of methicillin-resistant Staphylococcus aureus (MRSA) infection in some health institutions in the United States, but has rarely been adopted in institutions from developing countries where resources are limited. We describe our experience of PD in the control of healthcare-associated infections (HAIs) due to MRSA in a Colombian hospital with the aim of reducing HAI rates through a cultural change in processes...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065199/long-term-effectiveness-of-plasma-derived-hepatitis-b-vaccine-22-28-years-after-immunization-in-a-hepatitis-b-virus-endemic-rural-area-is-an-adult-booster-dose-needed
#17
H Li, G J Li, Q Y Chen, Z L Fang, X Y Wang, C Tan, Q L Yang, F Z Wang, F Wang, S Zhang, S L Bi, L P Shen
Longan County is considered a highly endemic area for hepatitis B virus (HBV). The plasma-derived vaccine has been used in newborns in this area since 1987. A cross-sectional survey was conducted to evaluate the long-term effectiveness of this vaccine. In total, 1634 participants born during 1987-1993 and who had received a series of plasma-derived HB vaccinations at ages 0, 1, and 6 months were enrolled. Serological HBV markers were detected and compared with previous survey data. Overall the prevalence of hepatitis B surface antigen (HBsAg) in all participants was 3·79%; 3·47% of subjects who had received the first dose within 24 h were HBsAg positive, and 8·41% of subjects who had received a delayed first dose were also HBsAg positive...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065193/incidence-of-surgical-site-infections-cannot-be-derived-reliably-from-point-prevalence-survey-data-in-dutch-hospitals
#18
A P Meijs, J A Ferreira, S C DE Greeff, M C Vos, M B G Koek
Thorough studies on whether point prevalence surveys of healthcare-associated infections (HAIs) can be used to reliably estimate incidence of surgical site infections (SSIs) are scarce. We examined this topic using surveillance data of 58 hospitals that participated in two Dutch national surveillances; HAI prevalence and SSI incidence surveillance, respectively. First, we simulated daily prevalences of SSIs from incidence data. Subsequently, Rhame & Sudderth's formula was used to estimate SSI incidence from prevalence...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065185/predictors-of-immunodeficiency-related-death-in-a-cohort-of-low-income-people-living-with-hiv-a-competing-risks-survival-analysis
#19
M F P M Albuquerque, D N Alves, C C Bresani Salvi, J D L Batista, R A A Ximenes, D B Miranda-Filho, H R L Melo, M Maruza, U R Montarroyos
We conducted a survival analysis with competing risks to estimate the mortality rate and predictive factors for immunodeficiency-related death in people living with HIV/AIDS (PLWH) in northeast Brazil. A cohort with 2372 PLWH was enrolled between July 2007 and June 2010 and monitored until 31 December 2012 at two healthcare centres. The event of interest was immunodeficiency-related death, which was defined based on the Coding Causes of Death in HIV Protocol (CoDe). The predictor variables were: sociodemographic characteristics, illicit drugs, tobacco, alcohol, nutritional status, antiretroviral therapy, anaemia and CD4 cell count at baseline; and treatment or chemoprophylaxis for tuberculosis (TB) during follow-up...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065171/zoonotic-diseases-in-south-american-camelids-in-england-and-wales
#20
K Halsby, D F Twomey, C Featherstone, A Foster, A Walsh, K Hewitt, D Morgan
The number of South American camelids (SACs) in England and Wales is increasing and with this comes a risk of new and emerging infections. Although classified as livestock, these animals are also treated as pets and may be in regular contact with humans. This paper reviews zoonotic diseases that have been identified in SACs in England and Wales, and which pose a potential risk to human health. We also highlight the importance of surveillance continuing to capture information on infections in SACs for the protection of both public and animal health...
January 9, 2017: Epidemiology and Infection
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