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Journal of Korean Medical Science

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https://www.readbyqxmd.com/read/28480667/letter-to-the-editor-central-nervous-system-involvement-in-relapsing-polychondritis-a-rare-and-difficult-diagnosis-a-case-report
#1
LETTER
Julien Le Marec, Stéphanie Jobard, Adrien Bigot, Benjamin Terrier, Jean Philippe Cottier, Frédéric Bastides, Elisabeth Diot
No abstract text is available yet for this article.
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480666/avoiding-inappropriate-authorship
#2
EDITORIAL
Sung Tae Hong
No abstract text is available yet for this article.
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480665/dend-syndrome-with-heterozygous-kcnj11-mutation-successfully-treated-with-sulfonylurea
#3
Ja Hyang Cho, Eungu Kang, Beom Hee Lee, Gu Hwan Kim, Jin Ho Choi, Han Wook Yoo
Permanent neonatal diabetes mellitus (PNDM) is caused by mutations in the ATP-sensitive potassium channel (KATP channel) subunits. Developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome is the most severe form of PNDM and is characterized by various neurologic features. We report on a patient with DEND syndrome following initial misdiagnosis with type 1 DM, who was successfully switched from insulin to sulfonylurea therapy. A 50-day-old male presented with fever and seizure, complicated by persistent hyperglycemia...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480664/clinical-and-genetic-features-of-coxiella-burnetii-in-a-patient-with-an-acute-febrile-illness-in-korea
#4
Seung Hun Lee, Jung Yeon Heo, Hae Kyung Lee, Yeong Seon Lee, Hye Won Jeong, Seon Do Hwang
Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis of acute Q fever was confirmed by seroconversion using indirect immunofluorescence antibody assays. Phylogenetic analysis demonstrated high sequence similarity (99.6%-100%) with C. burnetii 16S rRNA sequences identified from the reservoir...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480663/correlations-between-tumor-to-background-ratio-on-breast-specific-gamma-imaging-and-prognostic-factors-in-breast-cancer
#5
Soo Jin Lee, Yun Young Choi, Chanwoo Kim, Min Sung Chung
The purpose of this study was to investigate the correlations between tumor-to-background ratio (TBR) obtained from breast-specific gamma imaging (BSGI) and the prognostic factors of breast cancer. Sixty-seven patients with invasive ductal carcinoma who underwent preoperative BSGI were enrolled. The BSGI images were visually scored from 1 to 5 according to a breast imaging reporting and data system (BIRADS). The TBR results obtained from positive BSGI images were compared according to the following prognostic factors: tumor size; axillary lymph node metastasis; nuclear grade (NG); histologic grade (HG); subtype; Ki-67; and the expression profile of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480662/impact-of-neurointensivist-co-management-on-the-clinical-outcomes-of-patients-admitted-to-a-neurosurgical-intensive-care-unit
#6
Jeong Am Ryu, Jeong Hoon Yang, Chi Ryang Chung, Gee Young Suh, Seung Chyul Hong
Limited data are available on improved outcomes after initiation of neurointensivist co-management in neurosurgical intensive care units (NSICUs) in Korea. We evaluated the impact of a newly appointed neurointensivist on the outcomes of neurosurgical patients admitted to an intensive care unit (ICU). This retrospective observational study involved neurosurgical patients admitted to the NSICU at Samsung Medical Center between March 2013 and May 2016. Neurointensivist co-management was initiated in October 1 2014...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480661/a-randomized-placebo-controlled-double-blind-multi-center-therapeutic-confirmatory-study-to-evaluate-the-safety-and-efficacy-of-avanafil-in-korean-patients-with-erectile-dysfunction
#7
Hyun Jun Park, Sae Woong Kim, Je Jong Kim, Sung Won Lee, Jae Seung Paick, Tae Young Ahn, Kwangsung Park, Jong Kwan Park, Nam Cheol Park
A multi-center, randomized, double-blind, placebo-controlled study was conducted with 158 subjects who were randomized to placebo or avanafil 50, 100, and 200 mg on demand for 8 weeks to evaluate the safety, tolerability, and efficacy of avanafil in the treatment of erectile dysfunction (ED) in Korean men. The primary outcome was the erectile function (EF) domain score of the International Index of Erectile Function (IIEF) questionnaire. Secondary outcomes included changes in the scores of IIEF questions 3 and 4 (IIEF Q3, Q4) from baseline, changes in all domain scores in the IIEF from baseline, Sexual Encounter Profile questions 2-5 (SEP2-5), the Global Efficacy Assessment Question (GEAQ), and the number of subjects whose EF domain score at the 8th week visit was ≥ 26...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480660/antibiotic-prophylaxis-in-radical-prostatectomy-comparison-of-2-day-and-more-than-2-day-prophylaxis
#8
Bosung Shin, Ho Seok Chung, Eu Chang Hwang, Seung Il Jung, Dong Deuk Kwon
The efficacy of antibiotic prophylaxis in radical prostatectomy (RP) remains to be established. We retrospectively compared the occurrence of perioperative infections after RP between the 2 different antibiotic protocols. This study involved 428 cases of laparoscopic radical prostatectomy (LRP). After excluding patients who had no perioperative urine culture data, 313 consecutive patients who underwent LRP for prostate carcinoma were classified into 2 groups according to the duration of antimicrobial prophylaxis...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480659/daily-mean-temperature-and-urolithiasis-presentation-in-six-cities-in-korea-time-series-analysis
#9
Byung Hoon Chi, In Ho Chang, Se Young Choi, Dong Churl Suh, Chong Won Chang, Yun Jung Choi, Seo Yeon Lee
Seasonal variation in urinary stone presentation is well described in the literature. However, previous studies have some limitations. To explore overall cumulative exposure-response and the heterogeneity in the relationships between daily meteorological factors and urolithiasis incidence in 6 major Korean cities, we analyzed data on 687,833 urolithiasis patients from 2009 to 2013 for 6 large cities in Korea: Seoul, Incheon, Daejeon, Gwangju, Daegu, and Busan. Using a time-series design and distributing lag nonlinear methods, we estimated the relative risk (RR) of mean daily urolithiasis incidence (MDUI) associated with mean daily meteorological factors, including the cumulative RR for a 20-day period...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480658/effects-of-combination-therapy-of-alendronate-and-hormonal-therapy-on-bone-mineral-density-in-postmenopausal-korean-women-multicenter-randomized-controlled-clinical-trial
#10
Byung Koo Yoon, Dong Yun Lee, Man Chul Park, Soo Hyun Cho, Hyoung Moo Park, Young Min Choi
This study evaluated the effects of combination treatment with alendronate (ALEN) and hormone therapy (HT) on bone mineral density (BMD) in postmenopausal Korean women. This multicenter, randomized, controlled clinical trial enrolled 344 postmenopausal women with low BMD. The women received HT (0.625 mg/day of conjugated equine estrogen and 2.5 mg/day of medroxyprogesterone acetate) alone or in combination with ALEN (10 mg/day) for 1 year. Changes in BMD and biochemical markers of bone turnover were evaluated...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480657/urinary-glucose-screening-for-early-detection-of-asymptomatic-type-2-diabetes-in-jeonbuk-province-korean-schoolchildren
#11
Min Sun Kim, Dae Yeol Lee
This study aimed to investigate the prevalence of glucosuria and the characteristics of diabetes in schoolchildren as detected by a school urine glucose screening program implemented from 2010 to 2013 in the Jeonbuk province area of Korea. A total of 110 children without known diabetes were analyzed. They were checked with an oral glucose tolerance test (OGTT) with other laboratory tests and their clinical data were collected. A total of 707,238 schoolchildren from a school population of 1,064,999 were screened for glucosuria...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480656/breastfeeding-and-red-meat-intake-are-associated-with-iron-status-in-healthy-korean-weaning-age-infants
#12
Jeana Hong, Ju Young Chang, Sue Shin, Sohee Oh
The present study investigated risk factors for iron deficiency (ID) and iron deficiency anemia (IDA) during late infancy, including feeding type and complementary feeding (CF) practice. Healthy term Korean infants (8-15 months) were weighed, and questionnaires regarding delivery, feeding, and weaning were completed by their caregivers. We also examined levels of hemoglobin, serum iron/total iron-binding capacity, serum ferritin, and mean corpuscular volume (MCV). Among 619 infants, ID and IDA were present in 174 infants (28...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480655/effects-of-adrenal-androgen-levels-on-bone-age-advancement-in-prepubertal-children-using-the-ewha-birth-and-growth-cohort-study
#13
Jung Hyun Kwon, Hye Ah Lee, Young Ju Kim, Hwayoung Lee, Eun Ae Park, Su Jin Cho, Hye Sun Gwak, Eunhee Ha, Hyesook Park, Hae Soon Kim
Bone age (BA) advancement in prepubertal children may be associated with earlier onset of puberty and obesity. This study aimed to define the effects of adrenal androgen levels on the advancement of BA in prepubertal children, independent of obesity. During July and August 2011, we examined BA in 200 prepubertal children aged 7-9 years who were part of the Ewha Birth & Growth Cohort Study. BA was assessed by the Greulich-Pyle method. An index of BA advancement was calculated as the ratio of BA to chronological age (CA) (BA/CA), and this ratio was classified into 3 tertiles...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480654/vitamin-d-status-and-bone-mineral-density-in-children-with-inflammatory-bowel-disease-compared-to-those-with-functional-abdominal-pain
#14
Jenny Sohn, Eun Jae Chang, Hye Ran Yang
Low vitamin D has been implicated in reduced bone mineral density (BMD) in children with inflammatory bowel disease (IBD). Our study aimed to evaluate differences in serum 25-hydroxyvitamin D (25[OH]D) and total body less head (TBLH) BMD z-scores in children with Crohn's disease (CD), ulcerative colitis (UC), and those with abdominal pain-related functional gastrointestinal disorder (AP-FGID) as the control group. We also examined the correlation between serum 25(OH)D and TBLH BMD z-score, and factors that affect each of these parameters...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480653/the-rate-of-drug-resistant-tuberculosis-in-korean-children-and-adolescents-since-2007
#15
Hyun Jung Kim, Hyung Ho Yoon, Byung Wook Eun, Youngmin Ahn, Sungweon Ryoo, Hee Jin Kim
The incidence of drug-resistant tuberculosis (DR-TB) in pediatric populations is a critical indicator of national TB management and treatment strategies. Limited data exist regarding the rate of pediatric DR-TB. In this study, we aimed to analyze the status of DR-TB in Korean children from 2007 to 2013. We analyzed specimens submitted to the Korean Institute of Tuberculosis using Mycobacterium tuberculosis culture and drug susceptibility tests (DSTs) from January 2007 through December 2013. Specimens from patients ≤ 19 years of age were included...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480652/obesity-is-inversely-related-to-hydrogen-producing-small-intestinal-bacterial-overgrowth-in-non-constipation-irritable-bowel-syndrome
#16
Seung Eun Jung, Nam Seok Joo, Kyung Sun Han, Kyu Nam Kim
There have been inconsistent findings on the association of obesity and non-constipation irritable bowel syndrome (IBS). Small intestinal bacterial overgrowth (SIBO) with hydrogen (H₂) gas forming-microflora causes non-constipation IBS. But, the effect of H₂ producing SIBO on obesity in non-constipation IBS patients has not been studied yet. The aim of this study was to investigate the association between obesity and SIBO in non-constipation IBS patients. We reviewed the charts of patients who showed IBS symptoms along with the documented results of their lactulose hydrogen breath test (LHBT) for SIBO...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480651/the-perioperative-management-of-antithrombotic-therapies-using-enoxaparin
#17
Hun Gyu Hwang, So My Koo, Soo Taek Uh, Yang Ki Kim
Oral anticoagulant therapy is frequently and increasingly prescribed for patients at risk of arterial or venous thromboembolism (VTE). Although elective surgical or invasive procedures have necessitated temporary interruption of anticoagulants, managing these patients has been performed empirically and been poorly investigated. This study was designed to evaluate the adequacy of perioperative anticoagulation using enoxaparin. This was a retrospective, single-center study that evaluated the efficacy and safety of therapeutic-dose enoxaparin for bridging therapy in patients on long-term warfarin at Soonchunhyang University Hospital in Korea between August 2009 and July 2011...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480650/comparison-of-drug-eluting-balloon-followed-by-bare-metal-stent-with-drug-eluting-stent-for-treatment-of-de-novo-lesions-randomized-controlled-single-center-clinical-trial
#18
In Ho Chae, Chang Hwan Yoon, Jin Joo Park, Il Young Oh, Jung Won Suh, Young Seok Cho, Tae Jin Youn, Dong Ju Choi
The combined use of a drug-eluting balloon (DEB) and a bare metal stent (BMS) for the treatment of de novo non-small vessel coronary artery diseases (CAD) remains to be evaluated. We investigated the efficacy of a sequential treatment using a DEB together with a BMS implantation in comparison to a zotarolimus-eluting stent (ZES). This study was a prospective, randomized, open-label study. We designed it to demonstrate the non-inferiority of a sequential treatment using a DEB first followed by a BMS (DEB + BMS) compared with the use of a ZES...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480649/regional-difference-of-causative-pollen-in-children-with-allergic-rhinitis
#19
Myongsoon Sung, Sung Won Kim, Jeong Hee Kim, Dae Hyun Lim
The aim of this study was to investigate role of common pollen in Korean school-aged children with allergic rhinitis (AR) in 5 provinces (Incheon Metropolitan City-Gyeonggi Province, Chungcheongbuk-do, Gwangju Metropolitan City, Busan Metropolitan City, and Jeju Special Self-Governing Province), using a questionnaire and skin prick test, and to assess the differences among the residential regions. Among the enrolled 14,678 total children, 1,641 (22.0%) had AR. The sensitization rate to pollen (38.7%) was the second highest among examined allergens and significant differences were in the sensitization rates to trees, weeds, and grasses among the 5 provinces (P < 0...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28480648/korean-patients-undergoing-deceased-donor-liver-transplantation-for-alcoholic-liver-disease-have-non-inferior-survival-outcomes-than-for-hepatitis-b-virus-a-real-world-experience-without-minimum-abstinence-before-transplantation
#20
Suk Kyun Hong, Nam Joon Yi, Hyo Sin Kim, Sung Woo Ahn, Kyung Chul Yoon, Hyeyoung Kim, Kwang Woong Lee, Kyung Suk Suh
Few studies have compared outcomes in patients undergoing liver transplantation (LT) for hepatitis B virus (HBV) and alcoholic liver disease (ALD) in Asian countries in which living donor LT (LDLT) is dominant, where HBV is endemic and where there are no strict regulations on pre-transplant abstinence for ALD. This study compared post-LT outcomes of deceased donor LT (DDLT) in patients with ALD and HBV. Data from 220 patients who underwent primary DDLT at Seoul National University Hospital from January 2010 to December 2014, including 107 with HBV and 38 with ALD, were retrospectively analyzed...
June 2017: Journal of Korean Medical Science
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