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Journal of Korean Medical Science

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https://www.readbyqxmd.com/read/28776356/the-author-s-response-the-bacterial-etiology-of-otitis-media-and-specimen-collection
#1
LETTER
Sang Hoon Kim, Seung Geun Yeo
No abstract text is available yet for this article.
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776355/letter-to-the-editor-the-bacterial-etiology-of-otitis-media-and-specimen-collection
#2
LETTER
Ertugrul Guclu, Oguz Karabay
No abstract text is available yet for this article.
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776354/multidisciplinary-approach-to-refractory-upper-gastrointestinal-bleeding-case-series-of-angiographic-embolization
#3
Ko Eun Lee, Ki Nam Shim, Chung Hyun Tae, Min Sun Ryu, Sun Young Choi, Chang Mo Moon, Seong Eun Kim, Hey Kyung Jung, Sung Ae Jung
Although medical and endoscopic hemostasis is now considered as the first-line therapy for nonvariceal upper gastrointestinal (UGI) bleeding, refractory bleeding still occurs in 5%-10% of the patients. In these patients, transcatheter arterial embolization (TAE) or surgery is required, but research on embolization for unmanageable UGI bleeding in Korea is scanty. We reviewed the medical records of 518 patients who underwent endoscopic hemostasis during 4 years. Among these subjects, 8 patients who required embolization due to failure of endoscopic hemostasis were enrolled...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776353/autotransplantation-of-the-heart-for-recurrent-inflammatory-myofibroblastic-tumor
#4
Hyun Oh Park, Jun Ho Yang, Sung Hwan Kim, Seong Ho Moon, Joung Hun Byun, Jun Young Choi, Chung Eun Lee, Jung Wook Yang, Jong Woo Kim
We report a rare case of dyspnea caused by a cardiac tumor in a 53-year-old woman. The patient had undergone a cardiac tumor (inflammatory myofibroblastic tumor, 6.2 × 4.2 × 3.3 cm) resection at our institute 13 months earlier. We performed preoperative evaluations which revealed a cardiac tumor originating from the posterior wall of the left atrium. Cardiac autotransplantation surgery (cardiac explantation, ex vivo tumor resection, cardiac reconstruction, and cardiac reimplantation) was successfully performed for the complete resection of the recurrent tumor without major postoperative complications...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776352/role-of-the-abcb1-drug-transporter-polymorphisms-in-the-pharmacokinetics-of-oseltamivir-in-humans-a-preliminary-report
#5
Yu Jung Cha, Jong Lyul Ghim
Oseltamivir is a substrate of P-glycoprotein, an efflux drug transporter encoded by ABCB1. The objective of this study was to assess the role of ABCB1 (c.1236C>T, c.2677G>T/A, and c.3435C>T) polymorphisms in the pharmacokinetics of oseltamivir and its active metabolite, oseltamivir carboxylate in humans. Nineteen healthy male subjects were enrolled, and their ABCB1 polymorphisms were evaluated. After the oral administration of 75 mg oseltamivir, the plasma concentrations of oseltamivir and oseltamivir carboxylate were measured...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776351/the-utility-of-preliminary-patient-evaluation-in-a-febrile-respiratory-infectious-disease-unit-outside-the-emergency-department
#6
Jun Sik Kang, Byung Woo Jhun, Hee Yoon, Seong Mi Lim, Eunsil Ko, Joo Hyun Park, Sung Yeon Hwang, Se Uk Lee, Tae Rim Lee, Won Chul Cha, Tae Gun Shin, Min Seob Sim, Ik Joon Jo
A febrile respiratory infectious disease unit (FRIDU) with a negative pressure ventilation system was constructed outside the emergency department (ED) of the Samsung Medical Center in 2015, to screen for patients with contagious diseases requiring isolation. We evaluated the utility of the FRIDU during 1 year of operation. We analyzed 1,562 patients who were hospitalized after FRIDU screening between August 2015 and July 2016. The level of isolation recommended during their screening at the FRIDU was compared with the level deemed appropriate given their final diagnosis...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776350/comparison-of-baseline-characteristics-between-community-based-and-hospital-based-suicidal-ideators-and-its-implications-for-tailoring-strategies-for-suicide-prevention-korean-cohort-for-the-model-predicting-a-suicide-and-suicide-related-behavior
#7
C Hyung Keun Park, Jae Won Lee, Sang Yeol Lee, Jungjoon Moon, Se Hoon Shim, Jong Woo Paik, Shin Gyeom Kim, Seong Jin Cho, Min Hyuk Kim, Seokho Kim, Jae Hyun Park, Sungeun You, Hong Jin Jeon, Yong Min Ahn
In this cross-sectional study, we aimed to identify distinguishing factors between populations with suicidal ideation recruited from hospitals and communities to make an efficient allocation of limited anti-suicidal resources according to group differences. We analyzed the baseline data from 120 individuals in a community-based cohort (CC) and 137 individuals in a hospital-based cohort (HC) with suicidal ideation obtained from the Korean Cohort for the Model Predicting a Suicide and Suicide-related Behavior (K-COMPASS) study...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776349/lack-of-retirement-preparation-is-associated-with-increased-depressive-symptoms-in-the-elderly-findings-from-the-korean-retirement-and-income-panel-study
#8
Yeong Jun Ju, Woorim Kim, Sang Ah Lee, Joo Eun Lee, Hyojung Yoon, Eun Cheol Park
The aim of this study was to investigate the relationship between retirement preparation and depressive symptoms among Koreans 50 years of age or older. We used data from the 2009 to 2013 Korean Retirement and Income Panel Study (KReIS), which included data from the 365 baseline participants of 50 years of age or older. Our sample included only newly retired participants who worked in 2009, but had retired in the 2011 and 2013. To monitor the change in depressive symptoms according to retirement preparation, we used repeated measurement data...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776348/effect-of-individual-and-district-level-socioeconomic-disparities-on-cognitive-decline-in-community-dwelling-elderly-in-seoul
#9
Geon Ha Kim, Hye Ah Lee, Hyesook Park, Dong Young Lee, Inho Jo, Seong Hye Choi, Kyoung Gyu Choi, Jee Hyang Jeong
This study was to investigate the effects of individual and district-level socioeconomic status (SES) on the development of cognitive impairment among the elderly. A 3-year retrospective observational analysis (2010-2013) was conducted which included 136,217 community-dwelling healthy elderly who participated in the Seoul Dementia Management Project. Cognitive impairment was defined as 1.5 standard deviations below the norms on the Mini-mental status examination. In the individual lower SES group, the cumulative incidence rate (CIR) of cognitive impairment was 8...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776347/the-anti-inflammatory-effects-of-oral-formulated-tacrolimus-in-mice-with-experimental-autoimmune-encephalomyelitis
#10
Myung Jin Kim, Jung Joon Sung, Seung Hyun Kim, Jeong Min Kim, Gye Sun Jeon, Seog Kyun Mun, Suk Won Ahn
Multiple sclerosis (MS) is a T-lymphocyte-mediated autoimmune disease that is characterized by inflammation in the central nervous system (CNS). Although many disease-modifying therapies (DMTs) are presumed effective in patients with MS, studies on the efficacy and safety of DMTs for preventing MS relapse are limited. Therefore, we tested the immunosuppressive anti-inflammatory effects of oral-formulated tacrolimus (FK506) on MS in a mouse model of experimental autoimmune encephalomyelitis (EAE). The mice were randomly divided into 3 experimental groups: an untreated EAE group, a low-dose tacrolimus-treated EAE group, and a high-dose tacrolimus-treated EAE group...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776346/chronological-trends-in-clinical-and-urinary-metabolic-features-over-20-years-in-korean-urolithiasis-patients
#11
Ho Won Kang, Sung Pil Seo, Yun Sok Ha, Won Tae Kim, Yong June Kim, Seok Joong Yun, Wun Jae Kim, Sang Cheol Lee
Urolithiasis is common and is becoming more prevalent worldwide. This study assessed the chronological trends in clinical and urinary metabolic features over 20 years in Korean urolithiasis patients. We performed a retrospective analysis of 4,076 patients treated at our clinic from 1996 to 2015. Urinary metabolic data and stone analysis data were available for 1,421 and 723 patients (34.9% and 17.7%), respectively. Patients were categorized into 4 groups according to the date of initial diagnosis: group 1 (1996-2000, n = 897), group 2 (2001-2005, n = 1,018), group 3 (2006-2010, n = 1,043), and group 4 (2011-2015, n = 1,118)...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776345/influence-of-daytime-or-nighttime-dosing-with-solifenacin-for-overactive-bladder-with-nocturia-impact-on-nocturia-and-sleep-quality
#12
Taekmin Kwon, Tae Hee Oh, Seong Choi, Won Yeol Cho, Kweonsik Min, Jeong Zoo Lee, Kyung Hyun Moon
We compared changes in nocturia and sleep-related parameters between daytime and nighttime solifenacin dosing in patents with overactive bladder (OAB) and nocturia. We comparatively analyzed the data of a 12-week prospective, open-label, multicenter, randomized study. All 127 patients who presented to 5 centers in Korea for the treatment of OAB with nocturia between January 2011 and December 2013 were enrolled in this study. The patients were divided into 2 groups by medication timing: group 1, daytime (n = 62); and group 2, nighttime (n = 65)...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776344/validation-of-a-paper-and-pencil-test-battery-for-the-diagnosis-of-minimal-hepatic-encephalopathy-in-korea
#13
Jae Yoon Jeong, Dae Won Jun, Daiseg Bai, Ji Yean Kim, Joo Hyun Sohn, Sang Bong Ahn, Sang Gyune Kim, Tae Yeob Kim, Hyoung Su Kim, Soung Won Jeong, Yong Kyun Cho, Do Seon Song, Hee Yeon Kim, Young Kul Jung, Eileen L Yoon
The aim of this study was to validate a new paper and pencil test battery to diagnose minimal hepatic encephalopathy (MHE) in Korea. A new paper and pencil test battery was composed of number connection test-A (NCT-A), number connection test-B (NCT-B), digit span test (DST), and symbol digit modality test (SDMT). The norm of the new test was based on 315 healthy individuals between the ages of 20 and 70 years old. Another 63 healthy subjects (n = 31) and cirrhosis patients (n = 32) were included as a validation cohort...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776343/carbohydrate-intake-exhibited-a-positive-association-with-the-risk-of-metabolic-syndrome-in-both-semi-quantitative-food-frequency-questionnaires-and-24-hour-recall-in-women
#14
Jaeouk Ahn, Nam Soo Kim, Byung Kook Lee, Sunmin Park
We compared the usual nutrient intake in both the semi-quantitative food frequency questionnaire (SQFFQ) and 24-hour recall methods and determined the association between metabolic syndrome (MetS) risk and nutrient intake calculated by both methods in Korea National Health and Nutrition Examination Survey (KNHANES; 2012-2014) data. Adjusted odds ratios for MetS were calculated according to the intake of macronutrients, measured by the 2 methods in 10,286 adults, while controlling for covariates associated with MetS...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776342/could-vitamin-e-prevent-contrast-induced-acute-kidney-injury-a-systematic-review-and-meta-analysis
#15
Myung Hyun Cho, Soo Nyung Kim, Hye Won Park, Sochung Chung, Kyo Sun Kim
Several clinical studies have proposed a protective role for vitamin E (α-tocopherol) against contrast-induced acute kidney injury (CIAKI). The aim of study was to assess the effects of vitamin E for the prevention of CIAKI. A systematic review and meta-analysis was conducted using MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. Randomized controlled trials (RCTs) reporting the effects of vitamin E on CIAKI development and measurements of renal function were included. Four trials including 623 participants were analyzed in the meta-analysis...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776341/risk-of-stroke-in-elderly-dialysis-patients
#16
Seung Seok Han, Dong Ryeol Ryu, Kwon Wook Joo, Chun Soo Lim, Yong Lim Kim, Shin Wook Kang, Yon Su Kim, Dong Ki Kim
Despite the current knowledge about the risk of stroke and its related factors in general population, this issue in elderly patients receiving dialysis remains unresolved. Firstly, to compare the risk of stroke between hemodialysis (HD) and peritoneal dialysis (PD), data on 13,065 incident dialysis patients (aged ≥ 65 years; 10,675 in HD and 2,390 in PD) were retrieved from the Korean Health Insurance dataset. Secondly, to identify the risk factors of stroke amongst various clinical and laboratory parameters in HD, 980 elderly patients were retrospectively analyzed using an independent prospective cohort from 31 dialysis centers...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776340/abcg2-polymorphism-is-associated-with-hyperuricemia-in-a-study-of-a-community-based-korean-cohort
#17
Chang Nam Son, So Young Bang, Sang Hyon Kim, Yoon Kyoung Sung, Sang Cheol Bae, Jae Bum Jun
The purpose of the present study was to find novel loci associated with hyperuricemia using data from a genome-wide association study (GWAS) conducted on healthy Koreans. We conducted a GWAS using data from a community-based cohort study where 3,647 subjects aged 40-89 were recruited by the Korea National Institute of Health (KNIH). The community-based cohort consisted of subjects who did not suffer from any of 6 major diseases (hypertension, hyperlipidemia, diabetes, heart diseases, brain diseases, and cancers)...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776339/trends-in-malignancies-among-korean-patients-infected-with-human-immunodeficiency-virus-in-the-highly-active-antiretroviral-therapy-era
#18
Shinwon Lee, Sun Hee Lee, Jeong Eun Lee, Jin Suk Kang, Seung Geun Lee, Joo Seop Chung, Ihm Soo Kwak
Since the introduction of highly active antiretroviral therapy, the life span of people with human immunodeficiency virus (HIV) or AIDS (PWHA) has been extended significantly. Therefore, the importance of non-AIDS-defining cancers (NADCs), as well as AIDS-defining cancers (ADCs) has increased. There is little information concerning the epidemiology of malignancies in PWHA in Korea. A descriptive epidemiologic study was conducted at a tertiary care hospital in Korea. PWHA who visited Pusan National University Hospital from January 2000 to October 2014 were included...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776338/epidemiology-and-clinical-characteristics-of-zika-virus-infections-imported-into-korea-from-march-to-october-2016
#19
Doran Yoon, Seung Hwan Shin, Hee Chang Jang, Eu Suk Kim, Eun Hee Song, Song Mi Moon, So Youn Shin, Pyeong Gyun Choe, Jung Joon Sung, Eun Hwa Choi, Myoung Don Oh, Youngmee Jee, Nam Joong Kim
Zika is a re-emerging, mosquito-borne viral infection, which has been recently shown to cause microcephaly and Guillain-Barré syndrome. Since 2015 the number of infected patients has increased significantly in South America. The purpose of this study was to identify the epidemiologic and clinical characteristics of patients with Zika virus (ZIKV) infections in Korea. Patients who had visited areas of risk and tested positive in the ZIKV reverse transcriptase polymerase chain reaction (RT-PCR) in blood, urine, or saliva specimens were included...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28776337/changes-in-the-serotype-distribution-among-antibiotic-resistant-carriage-streptococcus-pneumoniae-isolates-in-children-after-the-introduction-of-the-extended-valency-pneumococcal-conjugate-vaccine
#20
Joon Kee Lee, Ki Wook Yun, Eun Hwa Choi, Sun Jung Kim, Seong Yeon Lee, Hoan Jong Lee
This study investigated the serotype distribution and antimicrobial resistance of 3,820 nasopharyngeal Streptococcus pneumoniae isolates from infants and children who presented with respiratory symptoms at Seoul National University Children's Hospital from July 2010 to June 2015 after the introduction of the extended-valency pneumococcal conjugate vaccines (PCVs). Serotypes and antimicrobial susceptibility were determined using the Quellung reaction and E-test, respectively. S. pneumoniae was isolated from 397 (10...
September 2017: Journal of Korean Medical Science
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