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Journal of Korean Medical Science

Sung Woo Lee, Ho Jun Chin
No abstract text is available yet for this article.
October 15, 2018: Journal of Korean Medical Science
Dong Seop Jeong, Woosik Han, Young Tak Lee, Wook Sung Kim, Jinyoung Song, I-Seok Kang, Pyo Won Park
Background: This study aimed to review the long-term clinical outcomes and graft patency of coronary artery bypass grafting (CABG) using arterial grafts in patients with Kawasaki disease (KD) affecting the coronary artery. Methods: Twenty patients with KD who underwent CABG from January 2002 to June 2014 were enrolled. There were 4 male (20%) and 16 female (80%) patients with ages at operation ranging from 2 to 42 years (median, 17.5 years). Our routine operative strategy was off-pump CABG with arterial grafts...
October 15, 2018: Journal of Korean Medical Science
Jae Ri Kim, Kyoung-Bun Lee, Wooil Kwon, Eunjung Kim, Sun-Whe Kim, Jin-Young Jang
Background: Intraductal papillary neoplasm of the bile duct (IPNB) is a recently defined entity and its clinical characteristics and classifications have yet to be established. We aimed to clarify the clinical features of IPNB and determine the optimal morphological classification criteria. Methods: From 2003 to 2016, 112 patients with IPNB who underwent surgery were included in the analysis. After pathologic reexamination by a specialized biliary-pancreas pathologist, previously suggested morphological and anatomical classifications were compared using the clinicopathologic characteristics of IPNB...
October 15, 2018: Journal of Korean Medical Science
Sung-Eun Kim, Eun Sun Jang, Moran Ki, Geum-Youn Gwak, Kyung-Ah Kim, Gi-Ae Kim, Do Young Kim, Dong Joon Kim, Man Woo Kim, Yun Soo Kim, Young Seok Kim, In Hee Kim, Chang Wook Kim, Ho Dong Kim, Hyung Joon Kim, Neung Hwa Park, Soon Koo Baik, Jeong Ill Suh, Byung-Cheol Song, Il Han Song, Jong Eun Yeon, Byung Seok Lee, Youn Jae Lee, Young Kul Jung, Woo Jin Chung, Sung Bum Cho, Eun-Young Cho, Hyun Chin Cho, Gab Jin Cheon, Hee Bok Chae, DaeHee Choi, Sung-Kyu Choi, Hwa Young Choi, Won Young Tak, Jeong Heo, Sook-Hyang Jeong
Background: Hepatitis B virus (HBV) infection leads to hepatic and extrahepatic manifestations including chronic kidney disease (CKD). However, the association between HBV and CKD is not clear. This study investigated the association between chronic HBV infection and CKD in a nationwide multicenter study. Methods: A total of 265,086 subjects who underwent health-check examinations in 33 hospitals from January 2015 to December 2015 were enrolled. HBV surface antigen (HBsAg) positive cases (n = 10,048), and age- and gender-matched HBsAg negative controls (n = 40,192) were identified...
October 15, 2018: Journal of Korean Medical Science
Tae Hee Lee, Joo-Hee Hwang, Woo Kon Lee, Min-Kyoung Shin, Hye Ryun Woo, Kyung Min Chung, Chang-Seop Lee
Pathogenic gram-negatives that produce 16S ribosomal RNA methyltransferases (16S RMTases) have already been distributed all over the world. To investigate the predominance of aminoglycoside resistance associated with 16S RMTases in Korea, we collected a total of 222 amikacin resistant Gram-negative clinical isolates from patient specimens between 1999 and 2015 from three hospital banks across Korea. ArmA and rmtB were the predominant 16S RMTase genes responsible for aminoglycoside-resistant isolates circulating in Korean community settings although only one rmtA -producing isolate was detected in 2006...
October 15, 2018: Journal of Korean Medical Science
Cho Ryok Kang, Ji Hwan Bang, Sung-Il Cho
Background: It is important that patients with human immunodeficiency virus (HIV) remain under medical care to improve their health and to reduce the potential for HIV transmission. We explored factors associated with missed visits for HIV medical care according to age group. Methods: Data were derived from a city-wide, cross-sectional survey of 812 HIV-infected adults in Seoul. Multiple logistic analyses were used to explore predictors of missed visits. Results: Of the 775 subjects, 99...
October 15, 2018: Journal of Korean Medical Science
Jong-Ik Park
No abstract text is available yet for this article.
October 8, 2018: Journal of Korean Medical Science
Jun Ah Lee
No abstract text is available yet for this article.
October 8, 2018: Journal of Korean Medical Science
So-Jung Park, Eun Jeong Nam, Yoon Jung Chang, Yong-Jae Lee, Hyun Jung Jho
Background: Establishing and designating specialized hospice palliative care units (HPCUs) has been an important part of national policy to promote hospice palliative care in Korea in the recent decade. However, few studies have sought to identify patterns and barriers for utilizing HPCU over the period of national policy implementation. We aimed to investigate factors related with utilizing HPCU for terminal cancer patients after consultation with a palliative care team (PCT). Methods: We reviewed medical records for 1,028 terminal cancer patients who were referred to the PCT of the National Cancer Center in 2010 and 2014...
October 8, 2018: Journal of Korean Medical Science
Hee Won Cho, Ji Won Lee, Youngeun Ma, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo
Background: By estimating the survival rates and exploring prognostic factors in pediatric patients with relapsed or progressed solid tumors, our purpose was to generate background data for future studies. Methods: We reviewed the medical records of 258 patients with solid tumors who experienced relapse/progression and received subsequent salvage treatment between 1996 and 2016. Results: A total of 60 patients remained progression-free during first-line salvage treatment, while the remaining 198 patients experienced relapse/progression again; 149 underwent second-line salvage treatment...
October 8, 2018: Journal of Korean Medical Science
Seonjin Woo, Sang Won Lee, Kwanghun Lee, Wan Seok Seo, Jonghun Lee, Hee-Cheol Kim, Seunghee Won
Background: The suicide rate in Korea has been the highest among the Organization for Economic Cooperation and Development countries since 2003. However, there is a lack of in-depth data regarding the characteristics of suicide attempters. Understanding the intent of suicide attempters will help improve the effectiveness of suicide prevention strategies. Therefore, to provide a resource for developing the necessary interventions, this study aimed to examine the differences in suicide-related and clinical variables according to the strength of suicidal intent...
October 8, 2018: Journal of Korean Medical Science
Yong-Soon Cho, Shi Hyang Lee, Hyeong-Seok Lim, Kyun-Seop Bae
Background: In type 2 diabetes mellitus therapy, fixed-dose combination (FDC) can offer not only benefits in glucose control via the combined use of agents, but also increase patient compliance. The aim of this study was to assess the pharmacokinetic equivalence of the high dose of the FDC tablet (gemigliptin/metformin sustained release [SR] 50/1,000 mg) and a corresponding co-administered dose of individual tablets. Methods: This study was randomized, open-label, single dose, two treatments, two-period, crossover study, which included 24 healthy subjects...
October 8, 2018: Journal of Korean Medical Science
Daedo Park, Sungsin Cho, Ahram Han, Chanjoong Choi, Sanghyun Ahn, Sang-Il Min, Jongwon Ha, Seung-Kee Min
Background: Limb salvage surgery with vascular reconstruction is currently considered as the standard treatment for extremity soft tissue sarcoma (STS), showing equivalent oncologic outcome compared with amputation. In this retrospective study, the surgical and functional outcomes after arterial or venous reconstruction in limb salvage surgery for STS were analyzed. Methods: Consecutive patients who underwent vascular resection and reconstruction as part of limb salvage surgery for extremity STS from July 2009 to June 2015 were included in this study...
October 1, 2018: Journal of Korean Medical Science
Aqeela Zahra, Jae-Hyun Park
Background: Exposure to secondhand smoke (SHS) is one of the biggest health hazards. Quantifying the related burden of disease (BOD) is a powerful tool for making evidence-based policies. This study calculated the BOD due to SHS at sub-national level using the most recent statistics of Korea. Methods: SHS related diseases were selected by the systematic review of previous studies. Population attributable fraction (PAF) was calculated by using the standard formula using prevalence of exposure derived from Community Health Survey (CHS) 2013...
October 1, 2018: Journal of Korean Medical Science
Jin-Hong Yoo
Carbapenem-resistant Enterobacteriaceae (CRE) are now spread worldwide. In Korea, the number of CRE isolation is rapidly increasing, and impending endemicity is a concern. To cope well with CRE, thorough infection control, such as active surveillance, early detection, strict contact precaution, cleaning the environment, and antibiotic stewardship is very important. Therapeutic options include polymyxin, tigecycline, fosfomycin or the combination of them with carbapenem, which is currently the mainstay of treatment...
October 1, 2018: Journal of Korean Medical Science
Seok Woo Hong, Hyun Sik Gong, Jung Wee Park, Young Hak Roh, Goo Hyun Baek
Background: The Quick Disabilities of the Arm, Shoulder, and Hand questionnaire (QuickDASH) is one of the most widely used questionnaires for assessing functional ability of the patients with upper extremity diseases. Carpal tunnel syndrome (CTS) is the most common neuropathic disease in the upper extremities. The aim of this study was to verify the validity, reliability, and responsiveness of Korean version of QuickDASH questionnaire (K-QuickDASH) in the patients with CTS. Methods: In total, 83 subjects who underwent open carpal tunnel release (CTR) operation were selected...
October 1, 2018: Journal of Korean Medical Science
Seong Cheol Kim, Sejun Park, Sang Hoon Song, Kun Suk Kim, Sungchan Park
Background: To investigate the clinicopathological characteristics of urinary bladder tumors, a rare malignancy, in patients 20 years or younger. Methods: Using a retrospective chart review among patients who received bladder surgery at 2 institutions between July 1996 and January 2013, we analyzed the clinicopathological characteristics of urinary bladder tumors in 21 pediatric patients (male:female = 4.25:1.00; mean age, 12.1 years). Results: Pathology revealed 9 urothelial tumors, 6 rhabdomyosarcomas, 1 low-grade leiomyosarcoma, 1 large cell neuroendocrine carcinoma, 1 inflammatory myofibroblastic tumor, and 3 cases of chronic inflammation without tumors (including 1 xanthogranulomatous inflammation)...
October 1, 2018: Journal of Korean Medical Science
Won Jin Lee
No abstract text is available yet for this article.
September 24, 2018: Journal of Korean Medical Science
Young-Hoon Yoon, Jung-Youn Kim, Sung-Hyuk Choi
Background: According to domestic studies, patients visiting the emergency departments (ED) with acute toxic exposure comprise 0.68%-5.5% of all ED patients, with various causes and motives. The purpose of this study is to investigate the clinical and social characteristics of patients with toxic exposure visiting the ED. Methods: This study spanned a period of five years, from January 1, 2009 to December 31, 2013. The data were extracted using the National Emergency Department Information System (NEDIS) and The Korea Health Insurance Review and Assessment Service (HIRA)...
September 24, 2018: Journal of Korean Medical Science
So-Ryoung Lee, Youngjin Cho, Myung-Jin Cha, Eue-Keun Choi, Jeong-Wook Seo, Seil Oh
Background: Although ganglionated plexi (GPs) are important in the pathogenesis of arrhythmia, their patterns of atrial innervation have remained unclear. We investigated patterns of GP innervation to cardiac atria and the neuroanatomical interconnections among GPs in an animal model. Methods: Atrial innervation by GPs was evaluated in 10 mongrel dogs using a retrograde neuronal tracer (cholera toxin subunit B [CTB] conjugated with fluorescent dyes). In Experiment 1, CTB was injected into the atria...
September 24, 2018: Journal of Korean Medical Science
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