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Journal of Korean Medical Science

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https://www.readbyqxmd.com/read/28378565/a-case-of-cap-polyposis-with-epidermal-nevus-in-an-infant
#1
Soon Chul Kim, Myoung Jae Kang, Yeon Jun Jeong, Pyoung Han Hwang
Cap polyposis is extremely rare in children. We report a case of an 11-month-old male infant who visited our hospital because of rectal prolapse and small amount of hematochezia lasting several days. He also had an epidermal nevus in the sacral area. Colonoscopy showed erythematous, multilobulated, circumferential, polypoid lesions with mucoid discharge from the rectum. He was diagnosed with cap polyposis by endoscopy and histologic examination. He was treated with surgical resection, and was closely followed up...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378564/factors-influencing-the-gross-motor-outcome-of-intensive-therapy-in-children-with-cerebral-palsy-and-developmental-delay
#2
Bo Young Hong, Leechan Jo, Joon Sung Kim, Seong Hoon Lim, Jung Min Bae
The study was designed to identify factors influencing the short term effect of intensive therapy on gross motor function in children with cerebral palsy or developmental delay. Retrospectively, total Gross Motor Function Measure-88 (GMFM-88) scores measured during the first and last weeks of intensive therapy were analyzed (n = 103). Good and poor responder groups were defined as those in the top and bottom 25% in terms of score difference, respectively. The GMFM-88 score increased to 4.67 ± 3.93 after 8 weeks of intensive therapy (P < 0...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378563/mean-hand-grip-strength-and-cut-off-value-for-sarcopenia-in-korean-adults-using-knhanes-vi
#3
Jun Il Yoo, Hana Choi, Yong Chan Ha
The purpose of this study was to report age- and gender-specific distribution of the hand grip strength (HGS) using data from the Korea National Health and Nutrition Examination Survey (KNHANES) VI-3 (2015) survey and determine cut-off values for low muscle strength of HGS of Koreans. Of a total of 7,380 participants, 4,553 were subjected to measurements of HGS, including 1,997 men and 2,556 women with a mean age of 49.3 years (range, 19-80 years). The mean ages of men and women were 49.0 and 49.5 years, respectively...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378562/early-rehabilitation-in-elderly-after-arthroplasty-versus-internal-fixation-for-unstable-intertrochanteric-fractures-of-femur-systematic-review-and-meta-analysis
#4
Jun Il Yoo, Yong Chan Ha, Jae Young Lim, Hyun Kang, Byung Ho Yoon, Hyunho Kim
The purpose of this study was to compare the outcomes focusing on the functional outcome and clinical results of replacement arthroplasty (AP) vs. internal fixation (IF) for the treatment of unstable intertrochanteric femoral fracture in elderly. Systematic review and meta-analysis were performed on 10 available clinical studies (2 randomized controlled trials and 8 comparative studies). Subgroup analysis was performed by type of methodological quality. Partial weight bearing time in AP group was earlier than that in IF group (SMD = -0...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378561/comparison-of-objective-and-subjective-changes-induced-by-multiple-pinhole-glasses-and-single-pinhole-glasses
#5
Won Soo Kim, In Ki Park, Young Kee Park, Yeoun Sook Chun
Multiple-pinhole (MPH) glasses are currently sold in many countries with unproven advertisements; however, their objective and subjective effects have not been investigated. Therefore, to investigate the effects of MPH glasses excluding the single-pinhole (SPH) effect, we compared the visual functional changes, reading speed, and ocular discomfort after reading caused by MPH and SPH glasses. Healthy 36 participants with a mean age of 33.1 years underwent examinations of pupil size, visual acuity (VA), depth of focus (DOF), and near point accommodation (NPA); tests for visual field (VF), contrast sensitivity (CS), stereopsis, and reading speed; and a survey of ocular discomfort after reading...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378560/what-kind-of-stress-is-associated-with-depression-anxiety-and-suicidal-ideation-in-korean-employees
#6
Young Chul Shin, Daeun Lee, Jinmi Seol, Se Won Lim
Various types of stress affect mental health in the form of mood disorders, anxiety disorders, and suicidal ideation. Recently, the increasing suicide rate in the working-age population has become a major mental health concern in Korea. Thus, we investigated what kind of stress influence depression, anxiety, and suicidal ideation in Korean employees. The study participants were 189,965 employees who attended health screenings and responded to the Center for Epidemiologic Study-Depression Scale, the Beck Anxiety Inventory, and a questionnaire on the major causes of stress and suicidal ideation...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378559/mortality-in-schizophrenia-and-other-psychoses-data-from-the-south-korea-national-health-insurance-cohort-2002-2013
#7
Woorim Kim, Suk Yong Jang, Sung Youn Chun, Tae Hoon Lee, Kyu Tae Han, Eun Cheol Park
Individuals with psychoses show excess mortality, which is a major public health concern. This study examined all-cause and suicide mortality rates in Korean patients diagnosed with schizophrenia, mood disorder, or mental and behavioral disorder due to psychoactive substance use and to compare this with that of the general population. Data were from the National Health Insurance cohort, 2002 to 2013. A total of 107,190 cases aged 15 years or over were included. Mortality rates per 100,000 person years (PY) were obtained...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378558/common-causes-of-postmenopausal-bleeding-in-korean-women-10-year-outcomes-from-a-single-medical-center
#8
Min Kyoung Kim, Yeon Soo Jung, Seung Joo Chon, Bo Hyon Yun, Sihyun Cho, Young Sik Choi, Byung Seok Lee, Seok Kyo Seo
The common causes of postmenopausal bleeding (PMB), according to the data from the western world, are atrophy, hormone replacement therapy (HRT), endometrial cancer, etc. We conducted a retrospective study to assess whether the causes of PMB in Korean postmenopausal women are similar to those already known. This retrospective study used 10-year medical records (March 2005 to December 2014) of 792 PMB women in the Yonsei University Health System. The data were divided into 2 categories by 5-year intervals to compare the differences between the 2 periods...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378557/reference-values-for-the-revised-anti-m%C3%A3-llerian-hormone-generation-ii-assay-infertile-population-based-study
#9
Joong Yeup Lee, Soyeon Ahn, Jung Ryeol Lee, Byung Chul Jee, Chung Hyon Kim, Soyeon Seo, Chang Suk Suh, Seok Hyun Kim
Anti-Müllerian hormone (AMH) is now accepted as an important clinical marker of ovarian reserve and is increasingly measured as an initial evaluation at infertility clinics. The aim of this study was to establish reference values for the revised second generation (Gen II) assay using population-based data. In this population-based cohort study, AMH data from unselected infertile women aged 25-45 years from June 2013 to June 2014 (n = 15,801) were collected. The AMH values were measured using the revised Gen II assay...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378556/rna-seq-for-gene-expression-profiling-of-human-necrotizing-enterocolitis-a-pilot-study
#10
Kyuwhan Jung, Insong Koh, Jeong Hyun Kim, Hyun Sub Cheong, Taejin Park, So Hyun Nam, Soo Min Jung, Cherry Ann Sio, Su Yeong Kim, Euiseok Jung, Byoungkook Lee, Hye Rim Kim, Eun Shin, Sung Eun Jung, Chang Won Choi, Beyong Il Kim, Eunyoung Jung, Hyoung Doo Shin
Necrotizing enterocolitis (NEC) characterized by inflammatory intestinal necrosis is a major cause of mortality and morbidity in newborns. Deep RNA sequencing (RNA-Seq) has recently emerged as a powerful technology enabling better quantification of gene expression than microarrays with a lower background signal. A total of 10 transcriptomes from 5 pairs of NEC lesions and adjacent normal tissues obtained from preterm infants with NEC were analyzed. As a result, a total of 65 genes (57 down-regulated and 8 up-regulated) revealed significantly different expression levels in the NEC lesion compared to the adjacent normal region, based on a significance at fold change ≥ 1...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378555/a-single-center-analysis-of-the-positivity-of-hepatitis-b-antibody-after-neonatal-vaccination-program-in-korea
#11
Yong Joo Kim, Peipei Li, Jong Myeon Hong, Keun Ho Ryu, Eunwoo Nam, Mi Soo Chang
The antibody to hepatitis B surface antigen (anti-HBs) seropositivity rate after 3 doses of hepatitis B virus (HBV) vaccination during infancy period is known to be higher than 90%. However, a considerable number of vaccines do not form protective anti-HBs or chronologic decrease of anti-HBs. We retrospectively collected data of HBV serologic test results in 20,738 individuals from 2000 to 2015. After exclusion criteria were applied, 19,072 individuals were included. We analyzed the anti-HBs seropositivity rate, anti-HBs disappearance rate, anti-HBs positive seroconversion rate after receiving a booster vaccine, and the difference in anti-HBs positivity between the 2 groups; group A (born before 2005, while both recombinant vaccines and plasma-derived vaccines were used) and group B (born after 2005, when only recombinant vaccines were used by national regulation)...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378554/reference-values-and-utility-of-serum-total-immunoglobulin-e-for-predicting-atopy-and-allergic-diseases-in-korean-schoolchildren
#12
Hye Young Kim, Jaehee Choi, Kangmo Ahn, Myung Il Hahm, So Yeon Lee, Woo Kyung Kim, Yoomi Chae, Yong Mean Park, Man Yong Han, Kee Jae Lee, Ho Jang Kwon, Seonwoo Kim, Heejin Yoo, Jihyun Kim
The present study aimed to investigate the distribution of total serum immunoglobulin E (IgE) levels in Korean schoolchildren and to evaluate its utility in the prediction of atopy and allergic diseases. A nationwide, cross-sectional survey was conducted in first grade students from randomly selected elementary and middle schools. Total IgE levels were measured by ImmunoCAP. Skin prick tests were performed for 18 common inhalant allergens to determine the presence of atopy. Children aged 12-13 years and parents of children aged 6-7 years were asked to complete questionnaire assessing allergic diseases...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378553/link-between-serum-pepsinogen-concentrations-and-upper-gastrointestinal-endoscopic-findings
#13
Sang Pyo Lee, Sun Young Lee, Jeong Hwan Kim, In Kyung Sung, Hyung Seok Park, Chan Sup Shim
The serum pepsinogen (PG) assay findings are correlated with the status of Helicobacter pylori infection, but there are controversies on the link with upper gastrointestinal (UGI) endoscopic findings. The aim of this study was to determine the significance of a serum PG assay for correlating with endoscopic findings in H. pylori-seroprevalent adult population. Korean adults who visited for a health check-up were included consecutively. Subjects after gastrectomy or H. pylori eradication were excluded. After completing the serum PG assay and anti-H...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378552/the-definition-of-past-tuberculosis-affects-the-magnitude-of-association-between-pulmonary-tuberculosis-and-respiratory-dysfunction-korea-national-health-and-nutrition-examination-survey-2008-2012
#14
Chang Jin Choi, Whan Seok Choi, Sook Young Lee, Kyung Soo Kim
Tuberculosis (TB) is associated with an increased risk of chronic lung impairment. The aim of this study was to compare the clinical characteristics and lung functions according to definition of past TB. We used the population-based, Korea National Health and Nutrition Examination Survey (KNHANES) (2008-2012) to analyze 13,522 subjects age 40 years or older who underwent spirometry and chest X-ray (CXR). Subjects with TB lesions on CXR (with or without a history of TB) were older, more likely to be male, ever smokers, and of low socioeconomic status than subjects with only a history of TB or without evidence of TB...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378551/changes-in-urinary-angiotensinogen-associated-with-deterioration-of-kidney-function-in-patients-with-type-2-diabetes-mellitus
#15
Min Jin Lee, Sang Soo Kim, In Joo Kim, Sang Heon Song, Eun Heui Kim, Ji Yeong Seo, Jong Ho Kim, Sungsu Kim, Yun Kyung Jeon, Bo Hyun Kim, Yong Ki Kim
Urinary angiotensinogen (AGT) is potentially a specific biomarker for the status of the intrarenal renin-angiotensin system (RAS) in patients with diabetes mellitus. We explored whether changes in urinary AGT excretion levels were associated with the deterioration of kidney function in type 2 diabetes patients with preserved kidney function. Urinary baseline AGT levels were measured in 118 type 2 diabetic patients who were not taking RAS blockers and who had estimated glomerular filtration rates (eGFRs) ≥ 60 mL/min/1...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378550/discrepancies-in-clinic-and-ambulatory-blood-pressure-in-korean-chronic-kidney-disease-patients
#16
Yun Kyu Oh, Ho Jun Chin, Shin Young Ahn, Jung Nam An, Jung Pyo Lee, Chun Soo Lim, Kook Hwan Oh
Blood pressure (BP) control is considered the most important treatment for preventing chronic kidney disease (CKD) progression and associated cardiovascular complications. However, clinic BP is insufficient to diagnose hypertension (HT) and to monitor overall BP control because it does not correlate well with ambulatory blood pressure monitoring (ABPM). We enrolled 387 hypertensive CKD patients (stages G1-G4, 58.4% male with median age 61 years) from 3 hospitals in Korea. HT of clinic BP and ABPM was classified as ≥ 140/90 and ≥ 130/80 mmHg, respectively...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378549/myxoid-and-sarcomatoid-variants-of-adrenocortical-carcinoma-analysis-of-rare-variants-in-single-tertiary-care-center
#17
Tae Yon Sung, Yun Mi Choi, Won Gu Kim, Yu Mi Lee, Tae Yong Kim, Young Kee Shong, Won Bae Kim, Dong Eun Song
The aim of this study is to describe rare variants of adrenocortical carcinoma (ACC) and to compare the prognosis with that of conventional ACC. We retrospectively reviewed 8 cases of myxoid variant, 1 sarcomatoid variant, and 14 cases of conventional ACC, who underwent surgical resection at the Asan Medical Center between 1996 and 2014. An analysis of the clinicopathological characteristics, including the Weiss score, Ki-67 labeling index, and reticulin framework assessment is presented. The mean age of patients with myxoid/sarcomatoid ACC was 45 years; 4 out of 9 patients were women...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378548/effect-of-coenzyme-q10-on-radiation-nephropathy-in-rats
#18
Yongkan Ki, Wontaek Kim, Yong Ho Kim, Donghyun Kim, Jin Sook Bae, Dahl Park, Hosang Jeon, Ju Hye Lee, Jayoung Lee, Jiho Nam
The kidney is one of the most radiosensitive organs in the abdominal cavity and is the dose-limiting structure in cancer patients receiving abdominal or total body irradiation. In the present study, the effect of coenzyme Q10 (CoQ10) on radiation nephropathy was evaluated in rats. A total of 72 rats were equally randomized into 4 groups: Control, CoQ10, irradiation with 10 Gy (RT) + placebo, or RT + CoQ10. The 2 RT groups received single 10 Gy of abdominal irradiation. The 2 CoQ10 groups were supplemented daily with 1 mL of soybean oil containing 10 mg/kg of CoQ10...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378547/deficiencies-of-circulating-mucosal-associated-invariant-t-cells-and-natural-killer-t-cells-in-patients-with-multiple-trauma
#19
Young Goun Jo, Hyun Jung Choi, Jung Chul Kim, Young Nan Cho, Jeong Hwa Kang, Hye Mi Jin, Seung Jung Kee, Yong Wook Park
Mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells are known to play important roles in autoimmunity, infectious diseases and cancers. However, little is known about the roles of these invariant T cells in multiple trauma. The purposes of this study were to examine MAIT and NKT cell levels in patients with multiple trauma and to investigate potential relationships between these cell levels and clinical parameters. The study cohort was composed of 14 patients with multiple trauma and 22 non-injured healthy controls (HCs)...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28378546/clinical-and-epidemiologic-characteristics-of-spreaders-of-middle-east-respiratory-syndrome-coronavirus-during-the-2015-outbreak-in-korea
#20
Chang Kyung Kang, Kyoung Ho Song, Pyoeng Gyun Choe, Wan Beom Park, Ji Hwan Bang, Eu Suk Kim, Sang Won Park, Hong Bin Kim, Nam Joong Kim, Sung Il Cho, Jong Koo Lee, Myoung Don Oh
Nosocomial transmission is an important characteristic of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. Risk factors for transmission of MERS-CoV in healthcare settings are not well defined. During the Korean outbreak in 2015, 186 patients had laboratory-confirmed MERS-CoV infection. Those suspected as a source of viral transmission were categorized into the spreader groups (super-spreader [n = 5] and usual-spreader [n = 10]) and compared to the non-spreader group (n = 171). Body temperature of ≥ 38...
May 2017: Journal of Korean Medical Science
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