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Cleveland Clinic Journal of Medicine

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https://www.readbyqxmd.com/read/29328903/dysmorphic-red-blood-cell-formation
#1
José Lucas Daza, Marcelo De Rosa, Graciela De Rosa
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328902/hypothermia-and-severe-first-degree-heart-block
#2
Kevin Bryan Uy Lo, Alison Nelson
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328901/a-50-year-old-woman-with-new-onset-seizure
#3
John R Queen, Samantha Bogner
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328900/detecting-and-managing-device-leads-inadvertently-placed-in-the-left-ventricle
#4
REVIEW
Richard G Trohman, Parikshit S Sharma
Inadvertent malpositioning of a cardiac implantable electronic device lead into the left ventricle is a rare complication of transvenous pacing and defibrillation. Rapid identification of lead position is critical during implantation and just after the procedure, with immediate correction required if malpositioning is detected. If lead misplacement is discovered late after implantation, the lead should be surgically removed or chronic anticoagulation with warfarin should be instituted.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328899/preventing-cardiovascular-disease-in-older-adults-one-size-does-not-fit-all
#5
REVIEW
Ariela R Orkaby, Oyere Onuma, Saadia Qazi, J Michael Gaziano, Jane A Driver
Frailty and cardiovascular disease are highly interconnected and increase in prevalence with age. Identifying frailty allows for a personalized cardiovascular risk prescription and individualized management of hypertension, hyperlipidemia, diabetes, and lifestyle in the aging population.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328898/idiopathic-hypercalciuria-can-we-prevent-stones-and-protect-bones
#6
REVIEW
Laura E Ryan, Steven W Ing
Idiopathic hypercalciuria increases the risk of urinary stones and osteoporosis. The aim of this review is to delineate our current understanding of idiopathic hypercalciuria in the context of bone health, specifically its definition, causes, epidemiology, laboratory evaluation, and potential treatments.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328897/high-users-of-healthcare-strategies-to-improve-care-reduce-costs
#7
REVIEW
Neil Siekman, Rick Hilger
A minority of patients consume a disproportionate amount of healthcare, especially in the emergency department. These "high users" are a small but complex group whose expenses are driven largely by low socioeconomic status, mental illness, and drug abuse; lack of social services also contributes. Several promising efforts aimed at improving quality and reducing healthcare costs for high users include care management organizations, patient care plans, and better discharge summaries.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328896/do-cardiac-risk-stratification-indexes-accurately-estimate-perioperative-risk-in-noncardiac-surgery-patients
#8
Rohan Mandaliya, Geno Merli
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328895/what-is-the-hepatitis-b-vaccination-regimen-in-chronic-kidney-disease
#9
Kheng Yong Ong, Hong Yun Wong, Giat Yeng Khee
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328894/frailty-and-cardiovascular-disease-a-two-way-street
#10
EDITORIAL
Emer Joyce
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328893/quality-in-urine-microscopy-the-eyes-of-the-beholder
#11
EDITORIAL
James F Simon, Arani Nanavati
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29328892/a-new-year-s-transition-and-looking-forward
#12
EDITORIAL
Brian F Mandell
No abstract text is available yet for this article.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281610/aortic-replacement-in-cardiac-surgery
#13
REVIEW
Eric E Roselli
The number of aorta procedures performed annually in the United States has grown substantially during the past decade. Cleveland Clinic is a leader in research on the risk of aortic dissection in patients with a bicuspid or tricuspid aortic valve and associated aneurysm, which has led to changes in the recommendations of when to operate. Safety and efficacy data support more proactive treatment for most patients with thoracic aortic aneurysm and/or dissection with a growing emphasis on the need to provide life-long care to patients with aortic conditions...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281609/improving-the-safety-and-efficacy-of-robotically-assisted-mitral-valve-surgery
#14
REVIEW
Stephanie Mick
To improve outcomes with robotically assisted mitral valve surgery, Cleveland Clinic conducted a study evaluating outcomes in 1,000 consecutive cases. Primary areas of interest were to determine whether increased surgical experience with robotic techniques improved outcomes and to identify opportunities that could improve procedural processes. Results showed that these surgeries were effective and safe in terms of improvements in procedure time, transfusion rates, stroke risk, number of mitral valve replacements, and number of conversions to sternotomy...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281608/a-new-generation-of-drug-eluting-stents-indications-and-outcomes-of-bioresorbable-vascular-scaffolds
#15
REVIEW
Ron Waksman
Drug-eluting stents (DES) are increasingly being used as a less invasive alternative to coronary artery bypass grafting. Early generation DES had durable polymers that provided acceptable efficacy outcomes but had high rates of stent thrombosis leading to myocardial infarction and death. Second-generation DES have improved outcomes by reducing stent thrombosis and recurrent stenosis. Newer DES with biodegradable polymers have similar efficacy as second-generation DES, but have higher rates of stent thrombosis...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281607/cabg-a-continuing-evolution
#16
REVIEW
Faisal Bakaeen
Use of coronary artery bypass grafting (CABG) has had a resurgence, as clinical trial data emerged showing that it remains the standard of care for patients with complex lesions. Debate exists regarding various factors, including endoscopic vs open vein-graft harvesting, single vs bilateral mammary artery grafts, radial artery vs saphenous vein grafts, right internal mammary artery vs radial artery grafts, and on-pump vs off-pump surgery. More recent developments include minimally invasive approaches, robotics, and hybrid revascularization, which are changing the risk-benefit ratio for this patient population...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281606/expanding-indications-for-tavr-the-preferred-procedure-in-intermediate-risk-patients
#17
REVIEW
David L Brown
Transcatheter aortic valve replacement (TAVR) has steadily replaced surgical aortic valve replacement (SAVR) in symptomatic patients with severe aortic stenosis, primarily those at high risk for surgical complications. As TAVR use increases, spurred by technological advances in valve design and patient preferences for the less-invasive procedure, studies have provided data supporting the efficacy and safety of TAVR. Recently, TAVR has expanded to intermediate-risk patients, increasing the potential patient population...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281605/trends-in-cardiovascular-risk-profiles
#18
REVIEW
Samir Kapadia
Outcomes for patients with coronary artery disease (CAD) have improved in the past 20 years likely due to advances in clinical care such as angiotensin-converting enzyme inhibitors, antiplatelet agents, and reduced time to cardiac cauterization procedures. But how have the risk factors for CAD changed in the past 2 decades? Analysis of nearly 4,000 patients with ST-elevation myocardial infarction (STEMI) at a tertiary care center found that patients presenting with acute STEMI are younger and more obese than in the past...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29281604/results-of-the-glagov-trial
#19
REVIEW
Steven E Nissen, Stephen J Nicholls
Statins therapy reduces atheroma in proportion to the reduction of low-density lipoprotein cholesterol (LDL-C). Proprotein convertase subtilisin--kexin type 9 (PCSK9) inhibitors are a new class of injectable human monoclonal antibodies shown to lower LDL-C when added to statin therapy. In a randomized, double-blind, placebo-controlled study, 968 patients with symptomatic coronary artery disease were treated with statins alone or combined with the PCSK9 inhibitor, evolocumab, and assessed for change in percent, total volume, and regression of coronary atheroma...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29257739/lung-transplant-candidates-for-referral-and-the-waiting-list
#20
REVIEW
Kenneth R McCurry, Marie M Budev
For patients with end-stage lung diseases, lung transplant may significantly extend survival and improve quality of life. Identifying patients that are likely to benefit from a lung transplant is essential to positive outcomes and to maximizing life expectancy for each patient. Prompt referral to and communication with an experienced lung transplant center allows for timely completion of the formal evaluation of candidacy and placement on the organ transplant waiting list. This article summarizes the selection criteria for lung transplant candidates, including when physicians should refer patients to transplant centers for evaluation and placement on the lung transplant waiting list...
December 2017: Cleveland Clinic Journal of Medicine
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