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Cleveland Clinic Journal of Medicine

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https://www.readbyqxmd.com/read/27861117/fibromuscular-dysplasia-advances-in-understanding-and-management
#1
REVIEW
Ellen K Brinza, Heather L Gornik
Several key findings in recent years have reshaped our understanding of fibromuscular dysplasia (FMD), an uncommon nonatherosclerotic disease of medium-sized arteries that affects mainly women. While the true prevalence of this disease remains unknown, studies suggest that more people may be affected than previously reported. Better understanding of the clinical manifestations and natural history of FMD and advances in diagnostic imaging have altered the clinical approach to managing patients with this uncommon vascular disease...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27861116/pcsk9-inhibition-a-promise-fulfilled
#2
REVIEW
Khendi White, Chaitra Mohan, Michael Rocco
The association of reduced proprotein convertase subtilisin/kexin type 9 (PCSK9) activity with reduced cardiovascular disease (CVD) events--and the need for add-ons to statin therapy to achieve treatment goals--has led to the rapid development and US Food and Drug Administration (FDA) approval of monoclonal antibody therapies to inhibit PCSK9. Now that PCSK9 inhibitors are approved by the FDA for use in certain patients, data from ongoing long-term clinical trials addressing tolerability, safety, and proof of additional reduction in CVD events are eagerly awaited...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27861115/leadless-cardiac-pacing-what-primary-care-providers-and-non-ep-cardiologists-should-know
#3
REVIEW
Erich L Kiehl, Daniel J Cantillon
Over the last 50 years, the use of transvenous pacemakers has been constrained by long-term complications that affect more than 1 in 10 patients, largely attributable to the endovascular leads and surgical pocket. Leadless cardiac pacing involves a self-contained pacemaker deployed directly into the heart without a lead or incisional access. The procedure has shown promise, eliminating pocket-related complications. Other advantages include postprocedural shoulder mobility and the ability to drive, shower, and bathe...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27861114/bioresorbable-stents-the-future-of-interventional-cardiology
#4
REVIEW
Stephen G Ellis, Haris Riaz
The introduction of stents has drastically reduced target-lesion restenosis rates associated with percutaneous coronary angioplasty. Bare-metal stents were the first introduced, followed by drug-eluting stents, both of which had significant impacts on the complication rates. Stents, however, have resulted in the emergence of stent thrombosis and stent restenosis, which can cause life-threatening cardiac complications. Three new technological approaches are being investigated to overcome these complications: stents coated with bioresorbable polymers, stents without polymers, and completely bioresorbable stents...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27861113/transcatheter-mitral-valve-replacement-a-frontier-in-cardiac-intervention
#5
REVIEW
Amar Krishnaswamy, Stephanie Mick, Jose Navia, A Marc Gillinov, E Murat Tuzcu, Samir R Kapadia
As transcatheter aortic valve replacement (TAVR) has become routine, device manufacturers and investigational cardiologists have set their sights on the mitral valve. Although transcatheter mitral valve replacement (TMVR) poses several technical challenges, they appear to be surmountable, and work is proceeding. Here we review the various devices being developed and preliminary results of trials in humans.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27861112/cardiovascular-disease-innovations-in-devices-and-techniques
#6
Maan A Fares
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824542/in-reply-menopausal-hormone-therapy
#7
LETTER
Laura Dorr Lipold, Pelin Batur, Risa Kagan
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824541/to-the-editor-menopausal-hormone-therapy
#8
LETTER
Holly L Thacker
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824540/plexiform-neurofibroma
#9
Satvinder Singh Bakshi
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824539/bilateral-earlobe-creases-and-coronary-artery-disease
#10
Abhishek Sharma, Chukwudi Obiagwu, Ekaterina Sikorskaya
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824538/left-ventricular-thrombosis-can-still-complicate-acute-myocardial-infarction
#11
Muhammad Umer Tariq, Ali M Tariq, Carmela D Tan, E Rene Rodriguez, Venu Menon
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824537/breaking-the-pain-contract-a-better-controlled-substance-agreement-for-patients-on-chronic-opioid-therapy
#12
REVIEW
Daniel G Tobin, Kristine Keough Forte, Summer Johnson McGee
"Pain contracts" for patients receiving long-term opioid therapy, though well-intentioned, often stigmatize the patient and erode trust between patient and physician. This article discusses how to improve these agreements to promote adherence, safety, trust, and shared decision-making.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824536/influenza-still-more-important-than-zika-virus-in-2016-2017
#13
REVIEW
Sherif Beniameen Mossad
Influenza kills and hospitalizes many people every year. Although the 2015-2016 influenza season was relatively mild, we should remain vigilant in our efforts to reduce the impact of future epidemics or pandemics by implementing universal influenza vaccination and early initiation of antiviral therapy for suspected cases. We don't expect influenza vaccine to prevent all cases of influenza, since immune response varies depending on age, underlying diseases, and immunosuppression.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824535/update-on-the-management-of-intestinal-failure
#14
REVIEW
Shishira Bharadwaj, Parul Tandon, John M Rivas, Anne Furman, Lisa Moccia, Ashley Ratliff, Abdullah Shatnawei, Ezra Steiger, Donald F Kirby
Intestinal failure is a serious complication of conditions such as inflammatory bowel disease, mesenteric ischemia, and radiation enteritis--and of extensive bowel resection performed because of these diseases. Imbalances of fluids and electrolytes and poor nutritional status manifest as chronic diarrhea or increased ostomy output. Prompt referral to a center specializing in intestinal rehabilitation is key to achieving nutritional homeostasis and, in some cases, can help the patient return to oral food intake...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824534/serotonin-syndrome-preventing-recognizing-and-treating-it
#15
REVIEW
Robert Z Wang, Vishal Vashistha, Sukhdeep Kaur, Nathan W Houchens
As the use of serotonergic agents to treat depression has increased, so too has the incidence of serotonin syndrome. We identify the common agents implicated in serotonin syndrome and the clinical tools to diagnose, manage, and prevent serotonergic toxicity.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824533/benefits-and-challenges-of-caring-for-international-patients
#16
REVIEW
Kelly A Cawcutt, John W Wilson
Increasing numbers of international patients are receiving care at US medical centers, entailing various challenges and benefits to all involved. Despite the potential challenges, the collective experiences can transform healthcare providers and their institutions into better physicians, better medical centers, and overall better members of a global society with increased awareness of the global human experience.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824532/seeking-medical-care-abroad-a-challenge-to-empathy
#17
EDITORIAL
Nizar N Zein
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27824531/the-peacock-and-the-doctor
#18
EDITORIAL
Brian F Mandell
No abstract text is available yet for this article.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27726834/correction-anemia-of-chronic-kidney-disease
#19
James F Simon, Georges Nakhoul
The article "Anemia of chronic kidney disease: Treat it, but not too aggressively" by Drs. Georges Nakhoul and James F. Simon (Cleve Clin J Med 2016; 83:613-624) contained a typographical error. In Table 2, the target ferritin level in chronic kidney disease is given as greater than 100 ng/dL, and for end-stage renal disease 200 to 1,200 ng/dL. Ferritin levels are measured in ng/mL, not ng/dL.
October 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27726833/in-reply-obstructive-sleep-apnea
#20
Mahesh B Manne, Gregory Rutecki
No abstract text is available yet for this article.
October 2016: Cleveland Clinic Journal of Medicine
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