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Journal of Head Trauma Rehabilitation

Nils Berginström, Peter Nordström, Urban Ekman, Johan Eriksson, Lars Nyberg, Anna Nordström
OBJECTIVE: To examine the effects of monoaminergic stabilizer (-)-OSU6162 on brain activity, as measured by blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI), in patients in the chronic phase of traumatic brain injury suffering from fatigue. SETTING: Neurorehabilitation clinic. PARTICIPANTS: Patients with traumatic brain injury received either placebo (n = 24) or active treatment (n = 28). Healthy controls (n = 27) went through fMRI examination at one point and were used in sensitivity analysis on normalization of BOLD response...
September 18, 2018: Journal of Head Trauma Rehabilitation
Katharine A Stromberg, Amma A Agyemang, Kristin M Graham, William C Walker, Adam P Sima, Jennifer H Marwitz, Cynthia Harrison-Felix, Jeanne M Hoffman, Allen W Brown, Jeffrey S Kreutzer, Randall Merchant
OBJECTIVE: To build decision tree prediction models for long-term employment outcomes of individuals after moderate to severe closed traumatic brain injury (TBI) and assess model accuracy in an independent sample. SETTING: TBI Model Systems Centers. PARTICIPANTS: TBI Model Systems National Database participants injured between January 1997 and January 2017 with moderate to severe closed TBI. Sample sizes were 7867 (year 1 postinjury), 6783 (year 2 postinjury), and 4927 (year 5 postinjury)...
September 18, 2018: Journal of Head Trauma Rehabilitation
Kevin M Kelly, Alex Kiderman, Sam Akhavan, Matthew R Quigley, Edward D Snell, Erik Happ, Andrea S Synowiec, Eric R Miller, Melissa A Bauer, Liza P Oakes, Yakov Eydelman, Charles W Gallagher, Thomas Dinehart, John Howison Schroeder, Robin C Ashmore
OBJECTIVE: The purpose of the study was to test the ability of oculomotor, vestibular, and reaction time (OVRT) metrics to serve as a concussion assessment or diagnostic tool for general clinical use. SETTING AND PARTICIPANTS: Patients with concussion were high school-aged athletes clinically diagnosed in a hospital setting with a sports-related concussion (n = 50). Control subjects were previously recruited male and female high school student athletes from 3 local high schools (n = 170)...
September 18, 2018: Journal of Head Trauma Rehabilitation
Natalie Kreitzer, Rachel Ancona, Cheryl McCullumsmith, Brad G Kurowski, Brandon Foreman, Laura B Ngwenya, Opeolu Adeoye
OBJECTIVE: Following traumatic brain injury (TBI), depressive symptoms are common and may influence recovery. We performed a meta-analysis to estimate the benefit of antidepressants following TBI and compare the estimated effects between antidepressants and placebo. PARTICIPANTS: Multiple databases were searched to find prospective pharmacological treatment studies of major depressive disorder (MDD) in adults following TBI. MAIN MEASURES: Effect sizes for antidepressant medications in patients with TBI were calculated for within-subjects designs that examined change from baseline after receiving medical treatment and treatment/placebo designs that examined the differences between the antidepressants and placebo groups...
August 30, 2018: Journal of Head Trauma Rehabilitation
Eric B Elbogen, Paul A Dennis, Elizabeth E Van Voorhees, Shannon M Blakey, Jacqueline L Johnson, Sally C Johnson, H Ryan Wagner, Robert M Hamer, Jean C Beckham, Tom Manly, Aysenil Belger
OBJECTIVE: To investigate effects of cognitive rehabilitation with mobile technology and social support on veterans with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). PARTICIPANTS: There were 112 dyads, comprised by a veteran and a family member or friend (224 participants in total). DESIGN: Dyads were randomized to the following: (1) a novel intervention, Cognitive Applications for Life Management (CALM), involving goal management training plus mobile devices for cueing and training attentional control; or (2) Brain Health Training, involving psychoeducation plus mobile devices to train visual memory...
August 30, 2018: Journal of Head Trauma Rehabilitation
Joseph A Wszalek, Lyn S Turkstra
OBJECTIVE: To characterize comprehension of written legal language in adults with and without traumatic brain injury (TBI). PARTICIPANTS: Nineteen adults with moderate-to-severe TBI (11 females) and 21 adults without TBI (13 females), aged 24 to 64 years. METHODS: Participants completed a multiple-choice assessment of legal-language comprehension, with written stimuli either presented in their original legal form or manipulated to simplify syntax or use more frequently occurring words...
August 30, 2018: Journal of Head Trauma Rehabilitation
Kimberly Lever, Jin Peng, Jennifer P Lundine, Sarah Caupp, Krista K Wheeler, Eric A Sribnick, Henry Xiang
OBJECTIVE: To examine barriers and facilitators for follow-up care of children with traumatic brain injury (TBI). SETTING: Urban children's hospital. PARTICIPANTS: Caregivers of children (aged 2-18 years) discharged from an inpatient unit with a TBI diagnosis in 2014-2015. DESIGN: Survey of caregivers. MAIN MEASURES: Caregiver-reported barriers and facilitators to follow-up appointment attendance...
August 30, 2018: Journal of Head Trauma Rehabilitation
Brad G Kurowski, Jeffery N Epstein, David W Pruitt, Paul S Horn, Mekibib Altaye, Shari L Wade
OBJECTIVE: To characterize the benefits and optimal dose of long-acting methylphenidate for management of long-term attention problems after childhood traumatic brain injury (TBI). DESIGN: Phase 2, randomized, double-masked, placebo-controlled, dose-titration, crossover clinical trial. SETTING: Outpatient, clinical research. PARTICIPANTS: Twenty-six children aged 6 to 17 years who were at least 6 months post-TBI and met criteria for attention-deficit hyperactivity disorder (ADHD) at the time of enrollment...
August 30, 2018: Journal of Head Trauma Rehabilitation
Elizabeth L Inness, Michelle Sweeny, Olinda Habib Perez, Cynthia Danells, Tharshini Chandra, Evan Foster, Cristina Saverino, Paul Comper, Mark Bayley, George Mochizuki
OBJECTIVE: To characterize the prevalence of, and relationship between, self-reported balance disturbance and performance-based balance impairment in the general population with concussion. SETTING: Rehabilitation hospital outpatient concussion clinic. PARTICIPANTS: One hundred six individuals with concussion (49 males, mean age = 32.4; SD = 11.5 years), mean (SD) = 5 (1.8) days postinjury. DESIGN: Cross-sectional observational study...
August 30, 2018: Journal of Head Trauma Rehabilitation
Maegan D Sady, Christopher G Vaughan, Gerard A Gioia
OBJECTIVE: To introduce and evaluate a measure of momentary symptom response to cognitive activity, a core feature of concussion. SETTING: Concussion clinic at a large regional children's hospital. PARTICIPANTS: Individuals aged 5 to 18 years, comprising 3 clinical groups: uninjured (n = 590), recently concussed but clinically recovered (n = 160), and recently concussed but not yet recovered (n = 570). DESIGN: Participants completed pretest symptom ratings, underwent neurocognitive assessment and completion of questionnaires, and then completed posttest ratings...
August 30, 2018: Journal of Head Trauma Rehabilitation
Carly A Cermak, Shannon E Scratch, Nick P Reed, Kim Bradley, Keelia L Quinn de Launay, Deryk S Beal
OBJECTIVE: This scoping review synthesizes the scholarly literature on cognitive communication impairments in traumatic brain injury (TBI) sustained during childhood to identify gaps in research, and make recommendations that will further the field of cognitive communication in pediatric TBI. METHODS: MEDLINE, PsycINFO, CINAHL, and EMBASE were searched to identify peer-reviewed studies that examined cognitive communication impairments in children who sustained a TBI between 3 months to 18 years of age...
August 30, 2018: Journal of Head Trauma Rehabilitation
Hilary Bertisch, Gigi Satris, Nancy Temkin, Jason Barber, Geoffrey T Manley
OBJECTIVE: To determine differences in rehabilitation trajectories and return to work (RTW) and social outcomes in individuals with mild traumatic brain injury (mTBI) with and without significant psychiatric histories at index hospitalization. SETTING: Three level 1 trauma centers participating in the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) consortium. PARTICIPANTS: A total of 305 individuals with index mTBI enrolled in the TRACK-TBI pilot project...
August 2, 2018: Journal of Head Trauma Rehabilitation
Vivian Kwan, Nicoline Bihelek, Vicki Anderson, Keith Yeates
OBJECTIVES: To map the number and type of smartphone applications available for persons with traumatic brain injury (TBI), evaluate validity of app content, and investigate evidence for any claims made. METHODS: We searched iTunes and Google Play and also completed a web search. The purpose of each app and any claims were extracted, and a search for best available evidence was performed. RESULTS: Seventy apps met our inclusion criteria (35 related to assessment, 11 to education, 9 to treatment/management, 8 to impact sensors, and 7 to symptom tracking)...
July 24, 2018: Journal of Head Trauma Rehabilitation
Peter C Fino, Jennifer Wilhelm, Lucy Parrington, Samuel Stuart, James C Chesnutt, Laurie A King
OBJECTIVE: To examine whether horizontal head turns while seated or while walking, when instrumented with inertial sensors, were sensitive to the acute effects of concussion and whether horizontal head turns had utility for concussion management. SETTING: Applied field setting, athletic training room. PARTICIPANTS: Twenty-four collegiate athletes with sports-related concussion and 25 healthy control athletes. DESIGN: Case-control; longitudinal...
July 24, 2018: Journal of Head Trauma Rehabilitation
Susruta Manivannan, Mohammad Al-Amri, Mark Postans, Laura Jayne Westacott, William Gray, Malik Zaben
OBJECTIVE: To evaluate current evidence for the effectiveness of virtual reality (VR) interventions in improving neurocognitive performance in individuals who have sustained a traumatic brain injury (TBI). METHODS: A systematic literature search across multiple databases (PubMed, EMBASE, Web of Science) for articles of relevance. Studies were evaluated according to study design, patient cohort, VR intervention, neurocognitive parameters assessed, and outcome. VR interventions were evaluated qualitatively with respect to methodology and extent of immersion and quantitatively with respect to intervention duration...
July 24, 2018: Journal of Head Trauma Rehabilitation
Lemma Ebssa Regasa, Yll Agimi, Katharine C Stout
OBJECTIVE: To evaluate the prevalence of delayed traumatic brain injury (TBI) diagnosis and cause of injury that resulted in a TBI diagnosis after military deployment. DESIGN: Medical record notes were reviewed in 2016 from a random sample of 1150 US military service members who had their first-time deployment in 2011 and likely sustained a TBI. Location and cause of the injury were extracted from the progress note for analysis. PARTICIPANTS AND SETTING: Active-duty US military service members who received an International Classification of Diseases, Ninth Revision code for a TBI diagnosis in a military facility...
July 24, 2018: Journal of Head Trauma Rehabilitation
Michael J Ellis, Patrick J McDonald, Ashley Olson, James Koenig, Kelly Russell
OBJECTIVE: To examine the prevalence of cervical spine injuries among children and adolescents referred with suspected and diagnosed sports-related concussion (SRC); and evaluate the effect of cervical spine dysfunction (CSD) on physician-documented clinical recovery following SRC. SETTING: A multidisciplinary pediatric concussion program. PARTICIPANTS: A total of 266 patients (6-19 years) referred with suspected SRC. DESIGN: A retrospective cohort study...
July 24, 2018: Journal of Head Trauma Rehabilitation
Susan B Perry, Barbara Billek-Sawhney, Jason Woollard, Susan Little, Amy Szalinski
OBJECTIVE: To compare balance, mobility, and functional outcomes across 3 age groups of older adults with traumatic brain injury; to describe differences between those discharged to private residences versus institutional care. SETTING: Acute inpatient rehabilitation facility. PARTICIPANTS: One hundred adults, mean age of 78.6 ± 7.9 years (range = 65-95 years), with an admitting diagnosis of traumatic brain injury. DESIGN: Retrospective case series...
July 24, 2018: Journal of Head Trauma Rehabilitation
Justin N Chee, Carol Hawley, Judith L Charlton, Shawn Marshall, Ian Gillespie, Sjaan Koppel, Brenda Vrkljan, Debbie Ayotte, Mark J Rapoport
OBJECTIVE: To synthesize knowledge of the risk of motor vehicle collision (MVC) following a traumatic brain injury (TBI) and the associated risk of driving impairment, as measured by on-road tests, computerized simulators, and self-reported or state-recorded driving records. METHODS: Our international team searched 7 databases for studies published between 1990 and 2015 of people with TBI, controls, and data concerning either MVC or driving impairment. The included articles examined the risk of MVC among people with TBI; we excluded studies that examined the risk of having a TBI associated with being involved in an MVC...
July 24, 2018: Journal of Head Trauma Rehabilitation
Stefan Bogdanov, Naomi Brookes, Adrienne Epps, Sharon L Naismith, Arthur Teng, Suncica Lah
OBJECTIVES: To characterize the sleep disturbance in children with moderate or severe traumatic brain injury (TBI), and to identify associated factors. SETTING: An urban tertiary pediatric healthcare facility. PARTICIPANTS: Children aged 5 to 15 years with a moderate TBI (n = 21), severe TBI (n = 23), or an orthopedic injury (OI; n = 38) comparable in age, gender, and socioeconomic status. DESIGN: Cohort study. MEASURES: Primary: Sleep Disturbance Scale for Children (SDSC)...
July 24, 2018: Journal of Head Trauma Rehabilitation
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