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Journal of Head Trauma Rehabilitation

Reidar P Lystad, Cate M Cameron, Rebecca J Mitchell
OBJECTIVE: To quantify and describe excess mortality attributable to traumatic brain injury (TBI) during the 12 months after hospitalization. DESIGN: Population-based matched cohort study using linked hospital and mortality data. SETTING: Australia. PARTICIPANTS: Individuals 18 years and older who were hospitalized with a principal diagnosis of TBI in 2009 (n = 6929) and matched noninjured individuals randomly selected from the electoral roll (n = 6929)...
November 8, 2018: Journal of Head Trauma Rehabilitation
Sean C Rose, Keith O Yeates, Darren R Fuerst, Patrick M Ercole, Joseph T Nguyen, Natalie M Pizzimenti
OBJECTIVE: To determine the association of repetitive subconcussive head impacts with functional outcomes in primary and high school tackle football players. SETTING: Youth football fields and an outpatient sports neurology clinic. PARTICIPANTS: A total of 112 primary school (n = 55, age 9-12 years) and high school (n = 57, age 15-18 years) football players. DESIGN: A prospective cohort study. MAIN MEASURES: Helmet-based sensors were used to record head impacts during practices and games during the 2016 football season...
October 12, 2018: Journal of Head Trauma Rehabilitation
Katharine A Stromberg, Amma A Agyemang, Kristin M Graham, William C Walker, Adam P Sima, Jennifer H Marwitz, Cynthia Harrison-Felix, Jeanne M Hoffman, Allen W Brown, Jeffrey S Kreutzer, Randall Merchant
OBJECTIVE: To build decision tree prediction models for long-term employment outcomes of individuals after moderate to severe closed traumatic brain injury (TBI) and assess model accuracy in an independent sample. SETTING: TBI Model Systems Centers. PARTICIPANTS: TBI Model Systems National Database participants injured between January 1997 and January 2017 with moderate to severe closed TBI. Sample sizes were 7867 (year 1 postinjury), 6783 (year 2 postinjury), and 4927 (year 5 postinjury)...
September 27, 2018: Journal of Head Trauma Rehabilitation
Nils Berginström, Peter Nordström, Urban Ekman, Johan Eriksson, Lars Nyberg, Anna Nordström
OBJECTIVE: To examine the effects of monoaminergic stabilizer (-)-OSU6162 on brain activity, as measured by blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI), in patients in the chronic phase of traumatic brain injury suffering from fatigue. SETTING: Neurorehabilitation clinic. PARTICIPANTS: Patients with traumatic brain injury received either placebo (n = 24) or active treatment (n = 28). Healthy controls (n = 27) went through fMRI examination at one point and were used in sensitivity analysis on normalization of BOLD response...
September 18, 2018: Journal of Head Trauma Rehabilitation
Kevin M Kelly, Alex Kiderman, Sam Akhavan, Matthew R Quigley, Edward D Snell, Erik Happ, Andrea S Synowiec, Eric R Miller, Melissa A Bauer, Liza P Oakes, Yakov Eydelman, Charles W Gallagher, Thomas Dinehart, John Howison Schroeder, Robin C Ashmore
OBJECTIVE: The purpose of the study was to test the ability of oculomotor, vestibular, and reaction time (OVRT) metrics to serve as a concussion assessment or diagnostic tool for general clinical use. SETTING AND PARTICIPANTS: Patients with concussion were high school-aged athletes clinically diagnosed in a hospital setting with a sports-related concussion (n = 50). Control subjects were previously recruited male and female high school student athletes from 3 local high schools (n = 170)...
September 18, 2018: Journal of Head Trauma Rehabilitation
Natalie Kreitzer, Rachel Ancona, Cheryl McCullumsmith, Brad G Kurowski, Brandon Foreman, Laura B Ngwenya, Opeolu Adeoye
OBJECTIVE: Following traumatic brain injury (TBI), depressive symptoms are common and may influence recovery. We performed a meta-analysis to estimate the benefit of antidepressants following TBI and compare the estimated effects between antidepressants and placebo. PARTICIPANTS: Multiple databases were searched to find prospective pharmacological treatment studies of major depressive disorder (MDD) in adults following TBI. MAIN MEASURES: Effect sizes for antidepressant medications in patients with TBI were calculated for within-subjects designs that examined change from baseline after receiving medical treatment and treatment/placebo designs that examined the differences between the antidepressants and placebo groups...
August 30, 2018: Journal of Head Trauma Rehabilitation
Eric B Elbogen, Paul A Dennis, Elizabeth E Van Voorhees, Shannon M Blakey, Jacqueline L Johnson, Sally C Johnson, H Ryan Wagner, Robert M Hamer, Jean C Beckham, Tom Manly, Aysenil Belger
OBJECTIVE: To investigate effects of cognitive rehabilitation with mobile technology and social support on veterans with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). PARTICIPANTS: There were 112 dyads, comprised by a veteran and a family member or friend (224 participants in total). DESIGN: Dyads were randomized to the following: (1) a novel intervention, Cognitive Applications for Life Management (CALM), involving goal management training plus mobile devices for cueing and training attentional control; or (2) Brain Health Training, involving psychoeducation plus mobile devices to train visual memory...
August 30, 2018: Journal of Head Trauma Rehabilitation
Joseph A Wszalek, Lyn S Turkstra
OBJECTIVE: To characterize comprehension of written legal language in adults with and without traumatic brain injury (TBI). PARTICIPANTS: Nineteen adults with moderate-to-severe TBI (11 females) and 21 adults without TBI (13 females), aged 24 to 64 years. METHODS: Participants completed a multiple-choice assessment of legal-language comprehension, with written stimuli either presented in their original legal form or manipulated to simplify syntax or use more frequently occurring words...
August 30, 2018: Journal of Head Trauma Rehabilitation
Kimberly Lever, Jin Peng, Jennifer P Lundine, Sarah Caupp, Krista K Wheeler, Eric A Sribnick, Henry Xiang
OBJECTIVE: To examine barriers and facilitators for follow-up care of children with traumatic brain injury (TBI). SETTING: Urban children's hospital. PARTICIPANTS: Caregivers of children (aged 2-18 years) discharged from an inpatient unit with a TBI diagnosis in 2014-2015. DESIGN: Survey of caregivers. MAIN MEASURES: Caregiver-reported barriers and facilitators to follow-up appointment attendance...
August 30, 2018: Journal of Head Trauma Rehabilitation
Brad G Kurowski, Jeffery N Epstein, David W Pruitt, Paul S Horn, Mekibib Altaye, Shari L Wade
OBJECTIVE: To characterize the benefits and optimal dose of long-acting methylphenidate for management of long-term attention problems after childhood traumatic brain injury (TBI). DESIGN: Phase 2, randomized, double-masked, placebo-controlled, dose-titration, crossover clinical trial. SETTING: Outpatient, clinical research. PARTICIPANTS: Twenty-six children aged 6 to 17 years who were at least 6 months post-TBI and met criteria for attention-deficit hyperactivity disorder (ADHD) at the time of enrollment...
August 30, 2018: Journal of Head Trauma Rehabilitation
Elizabeth L Inness, Michelle Sweeny, Olinda Habib Perez, Cynthia Danells, Tharshini Chandra, Evan Foster, Cristina Saverino, Paul Comper, Mark Bayley, George Mochizuki
OBJECTIVE: To characterize the prevalence of, and relationship between, self-reported balance disturbance and performance-based balance impairment in the general population with concussion. SETTING: Rehabilitation hospital outpatient concussion clinic. PARTICIPANTS: One hundred six individuals with concussion (49 males, mean age = 32.4; SD = 11.5 years), mean (SD) = 5 (1.8) days postinjury. DESIGN: Cross-sectional observational study...
August 30, 2018: Journal of Head Trauma Rehabilitation
Maegan D Sady, Christopher G Vaughan, Gerard A Gioia
OBJECTIVE: To introduce and evaluate a measure of momentary symptom response to cognitive activity, a core feature of concussion. SETTING: Concussion clinic at a large regional children's hospital. PARTICIPANTS: Individuals aged 5 to 18 years, comprising 3 clinical groups: uninjured (n = 590), recently concussed but clinically recovered (n = 160), and recently concussed but not yet recovered (n = 570). DESIGN: Participants completed pretest symptom ratings, underwent neurocognitive assessment and completion of questionnaires, and then completed posttest ratings...
August 30, 2018: Journal of Head Trauma Rehabilitation
Carly A Cermak, Shannon E Scratch, Nick P Reed, Kim Bradley, Keelia L Quinn de Launay, Deryk S Beal
OBJECTIVE: This scoping review synthesizes the scholarly literature on cognitive communication impairments in traumatic brain injury (TBI) sustained during childhood to identify gaps in research, and make recommendations that will further the field of cognitive communication in pediatric TBI. METHODS: MEDLINE, PsycINFO, CINAHL, and EMBASE were searched to identify peer-reviewed studies that examined cognitive communication impairments in children who sustained a TBI between 3 months to 18 years of age...
August 30, 2018: Journal of Head Trauma Rehabilitation
Bhavna Singichetti, Julie C Leonard, Alyssa R Janezic, Hongmei Li, Honggang Yi, Jingzhen Yang
OBJECTIVE: To examine the effect of state youth traumatic brain injury (TBI) legislation on pediatric emergency department (ED) utilization for sports and recreation-related mild TBIs (mTBIs). PARTICIPANTS: ED visits by children ages 5 to 18 years between 2006 and 2014 in the Pediatric Health Information System database (N = 452 900). DESIGN: Retrospective analysis. MAIN MEASURES: Rates of ED visits, and injury comparison groups (mTBI, moderate to severe TBI, minor head injury, and long bone fracture)...
November 2018: Journal of Head Trauma Rehabilitation
Brian L Edlow, Joseph J Fins
OBJECTIVE: To propose a practical ethical framework for how task-based functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) may be used in the intensive care unit (ICU) to identify covert consciousness in patients with acute severe traumatic brain injury (TBI). METHODS: We present 2 clinical scenarios in which investigational task-based fMRI and EEG were performed in critically ill patients with acute severe TBI who appeared unconscious on the bedside behavioral assessment...
November 2018: Journal of Head Trauma Rehabilitation
Marcel P Dijkers, Jennifer H Marwitz, Cynthia Harrison-Felix
The Traumatic Brain Injury Model Systems Center (TBIMSC) program was established by the National Institute on Disability, Independent Living, and Rehabilitation Research in 1987, with the goal of conducting research to improve the care and outcomes for individuals with moderate-to-severe traumatic brain injury (TBI). This article provides an update on TBIMSC research program activities since 2010 when a similar article was published. It includes (1) discussion of TBIMSC program management and infrastructure; (2) detail on the management, data quality, access, use, and knowledge translation of the TBIMSC National Database, with more than 16 000 participants with follow-up out to 25 years postinjury to date; (3) an overview of the TBIMSC site-specific studies and collaborative module research; (4) highlights of several collaborative initiatives between the TBIMSCs and other federal, advocacy, and research stakeholders; (5) an overview of the vast knowledge translation occurring through the TBIMSC program; and (6) discussion of issues that impact on the data collection methods for and contents of the TBIMSC National Database...
November 2018: Journal of Head Trauma Rehabilitation
Preeti Sunderaraman, Stephanie Cosentino, Karen Lindgren, Angela James, Maria Schultheis
OBJECTIVE: Primarily, to investigate the association between informant report and objective performance on specific financial capacity (FC) tasks by adults with chronic, moderate to severe acquired brain injury, and to examine the nature of misestimates by the informants. DESIGN: Cross-sectional design. SETTING: A postacute, community-based rehabilitation center. PARTICIPANTS: Data were obtained from 22 chronic acquired brain injury (CABI) adults, mean age of 46...
November 2018: Journal of Head Trauma Rehabilitation
Alexandra L Clark, Scott F Sorg, Kelsey Holiday, Erin D Bigler, Katherine J Bangen, Nicole D Evangelista, Mark W Bondi, Dawn M Schiehser, Lisa Delano-Wood
OBJECTIVE: Fatigue is a complex, multidimensional phenomenon that commonly occurs following traumatic brain injury (TBI). The thalamus-a structure vulnerable to both primary and secondary injuries in TBI-is thought to play a pivotal role in the manifestation of fatigue. We explored how neuroimaging markers of local and global thalamic morphometry relate to the subjective experience of fatigue post-TBI. METHODS: Sixty-three Veterans with a history of mild TBI underwent structural magnetic resonance imaging and completed questionnaires related to fatigue and psychiatric symptoms...
November 2018: Journal of Head Trauma Rehabilitation
Bilal Khokhar, Linda Simoni-Wastila, Julia F Slejko, Eleanor Perfetto, Min Zhan, Gordon S Smith
OBJECTIVE: To assess the relationship between posttraumatic brain injury statin use and (1) mortality and (2) the incidence of associated morbidities, including stroke, depression, and Alzheimer's disease and related dementias following injury. SETTING AND PARTICIPANTS: Nested cohort of all Medicare beneficiaries 65 years of age and older who survived a traumatic brain injury (TBI) hospitalization during 2006 through 2010. The final sample comprised 100 515 beneficiaries...
November 2018: Journal of Head Trauma Rehabilitation
William Lynch
No abstract text is available yet for this article.
September 2018: Journal of Head Trauma Rehabilitation
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