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Digestive Diseases

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https://www.readbyqxmd.com/read/29791895/effect-of-postprandial-administration-of-esomeprazole-on-reflux-symptoms-in-gastroesophageal-reflux-disease-a-randomized-controlled-trial
#1
Doron Boltin, Ibrahim Zvidi, Maria Raskin, Hen Kayless, Hemda Schmilovitz-Weiss, Rachel Gingold-Belfer, Yaron Niv, Ram Dickman
BACKGROUND: Esomeprazole is commonly administered with food; however, clinical data to support this practice are lacking. We aimed to determine the effect of postprandial ingestion of esomeprazole on reflux symptoms among patients with gastroesophageal reflux disease (GERD). METHODS: Consecutive patients with GERD adequately controlled with esomeprazole 40 mg daily, entered a 2-week lead-in period during which esomeprazole was administered 30 min before breakfast...
May 23, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29791893/reply-to-the-letter-by-dr-antonio-ponzetto-regarding-the-role-of-history-of-gastro-duodenal-ulcer-in-patients-with-upper-gastrointestinal-bleeding
#2
Yusaku Takatori, Motohiko Kato
No abstract text is available yet for this article.
May 23, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29791892/containing-the-costs-of-recurrent-gastro-duodenal-ulcer-bleeding
#3
Antonio Ponzetto, Natale Figura, Alessia Ciancio
No abstract text is available yet for this article.
May 23, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29763924/absence-of-complications-after-endoscopic-mucosal-biopsy
#4
Brian Johnson, Marc D Basson
BACKGROUND: There is no clarity with regard to the occurrence of serious complications from EGD-driven mucosal biopsy. This is important for considering both clinically indicated procedures and mucosal sampling for research. METHODS: We sought to quantify rates of serious complications from esophagogastroduodenoscopy (EGD) with biopsy. We studied 13,233 patients undergoing outpatient EGD with biopsy over 5 years in 2 North Dakota community hospitals, based on the reasoning that serious complications would cause hospitalization within 30 days...
May 15, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29763907/beyond-irritable-bowel-syndrome-the-efficacy-of-the-low-fodmap-diet-for-improving-symptoms-in-inflammatory-bowel-diseases-and-celiac-disease
#5
Anna Testa, Nicola Imperatore, Antonio Rispo, Matilde Rea, Raffaella Tortora, Olga Maria Nardone, Lucia Lucci, Grazia Accarino, Nicola Caporaso, Fabiana Castiglione
BACKGROUND AND AIM: To evaluate the usefulness of a low FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) diet on patients with irritable bowel syndrome (IBS), non-active inflammatory bowel diseases (IBD), and celiac disease (CD) on a gluten-free diet (GFD). METHODS: Dietetic interventional prospective study. IBS, IBD, and CD subjects were evaluated to check if they fulfilled the Rome III criteria. Each subject was educated to follow a low FODMAP diet after being evaluated by filling out questionnaires that assessed the quality of life (QoL) and symptoms experienced (IBS-SSS and SF-36), and was reevaluated after 1 and 3 months...
May 15, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29739003/hsi-newsletter-01-2018
#6
(no author information available yet)
No abstract text is available yet for this article.
May 8, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29698967/motorized-spiral-enteroscopy-for-occult-bleeding
#7
Laura Mans, Marianna Arvanitakis, Horst Neuhaus, Jacques Devière
Small-bowel disorders remain a diagnostic and therapeutic challenge due to intestinal length. Their management was revolutionized by the emergence of deep enteroscopy. In comparison with video capsule endoscopy, deep enteroscopy allows diagnostic and therapeutic interventions. Spiral enteroscopy (Spirus Medical Endo-Ease Overtube) achieves progression by gentle push and manual clockwise rotation inducing pleating of the small bowel on the endoscope. It has the advantage of shorter examination time and more stability during withdrawal but requires two operators...
April 26, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29698947/real-time-elastography-noninvasive-diagnostic-tool-in-the-evaluation-of-liver-stiffness-in-patients-with-chronic-viral-hepatitis-correlation-with-histological-examination
#8
Davide Ippolito, Valentina Schiavone, Cammillo Roberto Talei Franzesi, Alessandra Silvia Casiraghi, Silvia Girolama Drago, Luca Riva, Sandro Sironi
PURPOSE: To determine the value of real-time elastography (RTE) in the assessment of liver stiffness in patients with chronic viral hepatitis, correlating RTE data with the extent of fibrosis based on biopsy findings (Ishak score). METHODS: We evaluated 98 patients (45-75 years) with chronic viral hepatitis (51 HCV, 47 HBV) by using ultrasonography (US) study combined with RTE analysis. In the RTE images, relative tissue stiffness is expressed, according to color scale, with soft areas represented in green/red colors and hard areas in blue...
April 26, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29680836/endoscopic-duodenal-mucosal-resurfacing-for-the-treatment-of-type-2-diabetes
#9
Alia Hadefi, Vincent Huberty, Arnaud Lemmers, Marianna Arvanitakis, David Maggs, Guido Costamagna, Jacques Devière
Type 2 diabetes is a pandemic disease with an incidence that has risen steadily over recent decades. Experimental evidence in animals has demonstrated that intestinal bypass surgery of the upper small intestine, particularly the duodenum, has an important role in glucose homoeostasis. Furthermore, Roux-en-Y bypass performed as bariatric surgery has shown to correct hyperglycaemia from the first postoperative days in obese diabetic patients. Therefore, on the basis of these considerations, duodenal mucosal resurfacing was studied in type 2 diabetes patients as a minimally invasive procedure that could offer an alternative treatment for these patients...
April 20, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29672305/the-prognostic-prediction-role-of-preoperative-serum-albumin-level-in-patients-with-intahepatic-cholangiocarcinoma-following-hepatectomy
#10
Junyi Shen, Tianfu Wen, Chuan Li, Lvnan Yan, Bo Li, Jiayin Yang
BACKGROUND: There is little information regarding the role of preoperative serum albumin (ALB) in intrahepatic cholangiocarcinoma (ICC) patients who underwent liver resection. METHODS: Clinicopathological characteristics and survival rate of 91 ICC patients who underwent surgery between 2009 and 2013 were included in this study. The optimal cut-off for ALB were determined by plotting the receiver operating characteristics curves of ALB in predicting overall survival (OS) and utilizing the Youden index...
April 19, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29669354/effectiveness-and-safety-of-pylera%C3%A2-in-patients-infected-by-helicobacter-pylori-a-multicenter-retrospective-real-life-study
#11
Antonio Tursi, Marilisa Franceschi, Leonardo Allegretta, Edoardo Savarino, Rudi De Bastiani, Walter Elisei, Gianluca Baldassarre, Antonio Ferronato, Serena Scida, Chiara Miraglia, Antonio Penna, Claudio Licci, Giovanni Luca Rizzo, Giuseppe Pranzo, Claudio Cassieri, Giovanni Brandimarte, Marcello Picchio, Francesco Di Mario
BACKGROUND: Our aims were to assess the real life effectiveness and safety of the new bismuth-containing quadruple therapy in a large population of patients infected by Helicobacter pylori. METHODS: Consecutive dyspeptic H. pylori-positive patients were enrolled, both naïve for treatment and already unsuccessfully treated. Patients were treated with Pylera® 3 capsules 4 times/daily plus omeprazole 20 mg or esomeprazole 40 mg 2 times/daily for 10 days. Eradication was confirmed using a urea-breath test (at least 30 days after the end of the treatment)...
April 17, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29342468/the-role-of-history-of-gastro-duodenal-ulcer-in-patients-with-upper-gastrointestinal-bleeding
#12
Yusaku Takatori, Motohiko Kato, Yukie Sunata, Yuichiro Hirai, Yoko Kubosawa, Keichiro Abe, Yoshiaki Takada, Tetsu Hirata, Shigeo Banno, Michiko Wada, Satoshi Kinoshita, Hideki Mori, Kaoru Takabayashi, Miho Kikuchi, Masahiro Kikuchi, Masayuki Suzuki, Toshio Uraoka
BACKGROUND: Some scoring systems have been introduced to predict the need for performing urgent endoscopy in patients with upper gastrointestinal bleeding (UGIB). However, in an emergency situation, this intervention is insufficient and cannot easily provide the required treatment. AIM: To identify new risk factors that can predict the need for endoscopic intervention (EI) in UGIB patients. METHODS: This is a retrospective cross-sectional study...
January 17, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29514146/multiparametric-evaluation-predicts-different-mid-term-outcomes-in-crohn-s-disease
#13
Lucrezia Laterza, Anna Chiara Piscaglia, Laura Maria Minordi, Iolanda Scoleri, Luigi Larosa, Andrea Poscia, Fabio Ingravalle, Arianna Amato, Sergio Alfieri, Alessandro Armuzzi, Giovanni Cammarota, Antonio Gasbarrini, Franco Scaldaferri
AIM: To evaluate if a single and/or combined (clinical, endoscopic and radiological) assessment could predict clinical outcomes in Crohn's disease (CD). METHODS: We prospectively evaluated 57 CD cases who underwent both a colonoscopy and a CT-enterography (CTE). Harvey-Bradshaw Index (HBi), SES-CD (and/or Rutgeerts score) and the radiological disease activity were defined to stratify patients according to clinical, endoscopic and radiological disease activity respectively...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29495004/a-comparative-study-of-albumin-bilirubin-score-with-child-pugh-score-model-for-end-stage-liver-disease-score-and-indocyanine-green-r15-in-predicting-posthepatectomy-liver-failure-for-hepatocellular-carcinoma-patients
#14
Heng Zou, Xin Yang, Qing-Long Li, Qing-Xiang Zhou, Li Xiong, Yu Wen
BACKGROUND: The albumin-bilirubin (ALBI) grade is a newly proposed model for assessing the hepatic function. This study aimed to compare the value of the ALBI score with Child-Pugh score, model for end-stage liver disease (MELD) score and indocyanine green (ICG) R15 in predicting posthepatectomy liver failure (PHLF). METHODS: Patients undergoing curative resection for hepatocellular carcinoma (HCC) between January 2014 and June 2017 were enrolled. The values of the Child-Pugh score, MELD score, ICG R15 and ALBI score in predicting PHLF were evaluated...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29466790/elevated-faecal-calprotectin-levels-are-a-reliable-non-invasive-screening-tool-for-small-bowel-crohn-s-disease-in-patients-undergoing-capsule-endoscopy
#15
Hamid Yousuf, Umair Aleem, Roisin Egan, Pardeep Maheshwari, Jafaar Mohamad, Deidre McNamara
BACKGROUND: Approximately 10% of Crohn's disease (CD) patients have this disease affecting the small bowel (SB) beyond the reach of Ileo-colonoscopy. Capsule endoscopy (SBCE) is the recommended investigation for SB disease. An accurate and inexpensive biomarker would help identify at-risk patients. AIM: To examine the efficacy of faecal calprotectin (FC) and C-reactive protein (CRP) as predictors of SBCE findings in suspected and known CD. METHODS: A prospective observational study...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29421816/b1a-lymphocytes-cd19-cd5-deficiency-in-patients-with-crohn-s-disease-and-its-relation-with-disease-severity
#16
Rafael Gil-Borras, Carlos García-Ballesteros, Carmen Benet-Campos, Ignacio Catalán-Serra, Francisca López-Chuliá, Carmen Cuéllar, Juan Carlos Andreu-Ballester
BACKGROUND/AIMS: B1a cells (CD19+CD5+) are considered elements of the innate immune system. The aim of this study was to evaluate the frequency of B1a cells in the peripheral blood of patients with Crohn's disease (CD) and its relation with disease severity. METHODS: In this prospective study, a total of 128 subjects (64 CD patients and 64 healthy controls) were studied. B1a cells in peripheral blood, CD Activity Index, and Simple Endoscopic Score of B1a cells were studied...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29353268/non-invasive-diagnostic-criteria-for-hepatocellular-carcinoma-in-hepatitis-b-virus-endemic-areas-is-cirrhosis-indispensable
#17
Xiao-Wen Huang, Bing Liao, Yang Huang, Jin-Yu Liang, Quan-Yuan Shan, Shun-Li Shen, Xiao-Yan Xie, Ming-de Lu, Li-da Chen, Wei Wang
AIM: To confirm whether cirrhosis is indispensable for the non-invasive diagnostic criteria for hepatocellular carcinoma (HCC) in hepatitis B virus (HBV)-endemic areas. METHODS: Between January 2014 and December 2014, a total of 409 patients with pathologically proven focal liver lesions who underwent contrast-enhanced ultrasound (CEUS) were recruited from our institution. Clinical liver cirrhosis, HBV/HCV infection and HCC-typical vascular pattern of the targeted lesion on CEUS were evaluated...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29342455/endoscopic-full-thickness-resection-of-a-colonic-lateral-spreading-tumor
#18
Ana-Maria Bucalau, Arnaud Lemmers, Marianna Arvanitakis, Daniel Blero, Horst Neuhaus
The Full-Thickness Resection Device (FTRD; Ovesco Endoscopy, Tübingen, Germany) combines endoscopic full-thickness resection (EFTR) of gastrointestinal lesions with closure and cutting of the tissue in one integrated procedure. It provides en-bloc resection with an integral wall specimen for histopathological evaluation. This resection technique is partially filling of the gaps between the current procedures of choice in endoscopy (endoscopic mucosal resection and endoscopic submucosal dissection) and surgery...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29339645/multi-matrix-system-mesalazine-plus-rectal-mesalazine-in-the-treatment-of-mild-to-moderately-active-ulcerative-proctitis
#19
Antonio Cuomo, Dolores Sgambato, Mauro Valeriano D'Auria, Agnese Miranda, Emanuele Ferrante, Marco Romano
BACKGROUND: Mesalazine 1 g suppository/die is used for mild to moderately active ulcerative proctitis (UP). Whether addiction of Multi Matrix System (MMX) mesalazine increases the remission rate of UP and prevents proximal extension of disease is unknown. METHODS: This is a retrospective study on 116 outpatients with UP who had been treated with one of the following regimens: (1) MMX mesalazine 1.2 g/die plus mesalazine suppositories for 8 ± 2 weeks and, subsequently, MMX mesalazine 1...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29332096/higher-thrombin-antithrombin-iii-complex-levels-may-indicate-severe-acute-pancreatitis
#20
Sami Fidan, Murat Erkut, Arif Mansur Cosar, Yasar Yogun, Asım Örem, Mehmet Sönmez, Mehmet Arslan
AIM: Coagulation disorders may develop in association with severe acute pancreatitis (AP). Plasma thrombin-antithrombin III complex (TAT) levels are one of the principal markers of coagulation disorder. The purpose of this study was to evaluate TAT and other hemostatic parameters in patients with AP and to examine whether or not these parameters indicate the severity of AP. METHOD: Forty-six patients with AP (14 severe, 32 non-severe) and a 30-member healthy control group were recruited...
2018: Digestive Diseases
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