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Lasers in Medical Science

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https://www.readbyqxmd.com/read/29790013/effect-of-photobiomodulation-670-nm-associated-with-vitamin-a-on-the-inflammatory-phase-of-wound-healing
#1
A N Otterço, P Brassolatti, A L M Andrade, L R S Avó, P S Bossini, N A E Parizotto
Wound healing is a complex biological process with specific phases. Photobiomodulation (PBM) decreases the inflammatory infiltrate, stimulating fibroblast proliferation and angiogenesis, and therefore, is indicated for wound healing. Vitamin A is used to reverse the inhibitory effects on wound healing and accelerate the healthy granulation tissue. The study aimed to evaluate the effect of topical vitamin A and PBM (GaAlAs) in inflammatory phase of cutaneous wounds. Forty Wistar male rats were separated into four groups: (1) control (CG); (2) laser group (LG) GaAlAs, 670 nm, 30 mW, energy per point of 0...
May 22, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29790012/evaluation-of-a-nanocomposite-of-peg-curcumin-gold-nanoparticles-as-a-near-infrared-photothermal-agent-an-in-vitro-and-animal-model-investigation
#2
F Rahimi-Moghaddam, N Azarpira, N Sattarahmady
Hyperthermia is a promising alternative modality for the conventional cancer treatments. Nanoparticle-mediated photothermal therapy (PTT) has been widely applied for hyperthermia cancer therapy by a near-infrared light irradiation. Some special nanoparticles can convert light energy into heat and destroy the tumor cells. Inspired from the photothermal efficacy of the gold nanoparticles, here we synthesized, characterized, and applied novel photothermal polyethylene glycol-curcumin-gold nanoparticles (PEG-Cur-Au NPs) in cancer PTT...
May 22, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29777405/ability-of-blue-laser-imaging-with-magnifying-endoscopy-for-the-diagnosis-of-gastric-intestinal-metaplasia
#3
Honglei Chen, Yanan Liu, Yi Lu, Xutao Lin, Qiuning Wu, Jiacheng Sun, Chujun Li
We aimed to determine the utility of blue laser imaging (BLI) with magnifying endoscopy (BLI-ME) for the prediction and diagnosis of gastric intestinal metaplasia (GIM). Participants, aged between 40 and 75 years, undergoing gastroscopy from January to April 2017 were included in this study. The ability of BLI-ME and white light endoscopy (WLE) to detect GIM was assessed by comparing the endoscopic findings with the histological findings. The correlation between the grades of light blue crest (LBC) appearance and histology grade of GIM was calculated...
May 18, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29766330/laser-reduction-of-specific-microorganisms-in-the-periodontal-pocket-using-er-yag-and-nd-yag-lasers-a-randomized-controlled-clinical-study
#4
K Grzech-Leśniak, A Sculean, Boris Gašpirc
The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned into one of three treatment groups of 20 patients. The first group received scaling and root planing by hand instruments (SRP group), the second group received Er:YAG laser treatment alone (Er group), and the third group received combined treatment with Nd:YAG and Er:YAG lasers (NdErNd group)...
May 15, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29744754/less-is-more-similar-efficacy-in-three-sessions-and-seven-sessions-of-pulsed-dye-laser-treatment-in-infantile-port-wine-stain-patients
#5
Jiafang Zhu, Wenxin Yu, Tianyou Wang, Yijie Chen, Dongze Lyu, Lei Chang, Gang Ma, Xiaoxi Lin
Port-wine stains (PWS) affect 0.3 to 0.5% of newborns and pulsed dye laser (PDL) remains the treatment of choice. However, no reliable study regarding the benefits of more frequent has been conducted. We designed the present study to evaluate whether more frequent PDL treatments in infantile patients would achieve further lightening of erythema. We prospectively investigated 20 infants with PWS. Two adjacent sites were both treated for a 12-week duration and randomly allocated to be treated for seven sessions at 2-week intervals or three sessions at 6-week intervals...
May 10, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29744752/indocyanine-green-mediated-photobiomodulation-on-human-osteoblast-cells
#6
Gamze Bölükbaşı Ateş, Ayşe Ak, Bora Garipcan, Murat Gülsoy
Photobiomodulation (PBM) and photodynamic therapy (PDT) share similar mechanisms but have opposite aims. Increased levels of reactive oxygen species (ROS) in the target tissue in response to light combined photosensitizer (PS) application may lead to cell proliferation or oxidative damage depending on the ROS amount. The purpose of the present study is to investigate the effect of indocyanine green (ICG)-mediated PBM on osteoblast cells by measuring cell viability, proliferation, alkaline phosphatase (ALP) activity, mineralization, and gene expressions of three phenotypic osteoblast markers...
May 9, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29744751/bactericide-effect-of-methylene-blue-associated-with-low-level-laser-therapy-in-escherichia-coli-bacteria-isolated-from-pressure-ulcers
#7
Thais Ferreira Gomes, Matheus Masalskiene Pedrosa, Ana Claudia Laforga de Toledo, Veridiana Wanshi Arnoni, Mirian Dos Santos Monteiro, Davi Cury Piai, Silvia Helena Zacarias Sylvestre, Bruno Ferreira
The present study analyzed the bactericidal effect of methylene blue associated with low-level lasers on Escherichia coli isolated from a pressure ulcer. Microbiological material from a pressure ulcer was isolated using an aseptic swab, and antimicrobial activity was verified using the diffusion disc method. Methylene blue was used at concentrations of 0.001 and 0.005%, and low-level lasers of 670, 830, and 904 nm, with the energy densities of 4, 8, 10, and 14 J/cm2 , were tested on three plates each and combined with methylene blue of each concentration...
May 9, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29736759/in-vitro-impact-of-laser-irradiation-on-platelet-aggregation
#8
Eman A Shakir, Nabaa A Rasheed Naji
The review of blood optical and rheological parameters plays an important role in many medical routine diagnosis and therapeutic applications and is the best way to understand the mechanism of action of low-level laser irradiation on biological tissues. The aim of this study was to investigate the in vitro effect of laser radiation on platelet count and aggregation. Blood samples were obtained from 30 healthy volunteers; each sample was divided into four aliquots, one of them was considered as a control while the other three were exposed to three different laser doses...
May 7, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29732522/a-split-face-study-comparison-of-picosecond-alexandrite-laser-and-q-switched-nd-yag-laser-in-the-treatment-of-melasma-in-asians
#9
Mei-Ching Lee, Ying-Fang Lin, Sindy Hu, Yau-Li Huang, Shyue-Luen Chang, Chun-Yu Cheng, Chun-Shin Chang
To evaluate efficacy and safety of picosecond 755 nm alexandrite laser as compared to 1064 nm QS-Nd:YAG laser for melasma treatment in Asians. Twelve patients received 4 sessions of treatments at 1-month interval in a split-face manner. The right side of each patient's face received 755 nm picosecond laser, and the other side received 1064 nm QS-Nd:YAG laser. Zoom handpiece of 755 nm picosecond laser at fluence of 0.88-1.18 J/cm2 was applied. The treatment protocol used for 1064 nm QS-Nd:YAG laser was 8 mm spot size at fluence of 2...
May 7, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29732521/ten-year-follow-up-after-combined-coronary-artery-bypass-grafting-and-transmyocardial-laser-revascularization-in-patients-with-disseminated-coronary-atherosclerosis
#10
Janusz Konstanty-Kalandyk, Jacek Piątek, Anna Kędziora, Krzysztof Bartuś, Rafał Drwila, Tomasz Darocha, Grzegorz Filip, Bogusław Kapelak, Bryan HyoChan Song, Jerzy Sadowski
Coronary artery disease involving heavily calcified lesions has been associated with worse short- and long-term outcomes including increased mortality. This paper aims to evaluate long-term survival benefit when CABG + transmyocardial laser revascularization (TMLR) are performed on the hearts of patients with disseminated coronary atherosclerosis (DCA). This novel retrospective study was conducted between 1997 and 2002 and followed 86 patients with ischemic heart disease and severe DCA who underwent TMLR using a Holmium:YAG laser and/or CABG...
May 7, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29730821/evaluation-of-the-low-level-laser-therapy-application-parameters-for-skin-burn-treatment-in-experimental-model-a-systematic-review
#11
Patricia Brassolatti, Ana Laura Martins de Andrade, Paulo Sérgio Bossini, Albaiza Nicoletti Otterço, Nivaldo Antônio Parizotto
Burn is defined as a traumatic injury of thermal origin, which affects the organic tissue. Low-level laser therapy (LLLT) has gained great prominence as a treatment in this type of injury; however, the application parameters are still controversial in the literature. The aims of this study were to review the literature studies that use LLLT as a treatment in burns conducted in an experimental model, discuss the main parameters used, and highlight the benefits found in order to choose an appropriate therapeutic window to be applied in this type of injury...
May 5, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29728943/detection-of-white-spot-lesions-by-segmenting-laser-speckle-images-using-computer-vision-methods
#12
Luciano G Gavinho, Sidnei A Araujo, Sandra K Bussadori, João V P Silva, Alessandro M Deana
This paper aims to develop a method for laser speckle image segmentation of tooth surfaces for diagnosis of early stages caries. The method, applied directly to a raw image obtained by digital photography, is based on the difference between the speckle pattern of a carious lesion tooth surface area and that of a sound area. Each image is divided into blocks which are identified in a working matrix by their χ2 distance between block histograms of the analyzed image and the reference histograms previously obtained by K-means from healthy (h_Sound) and lesioned (h_Decay) areas, separately...
May 5, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29728942/evaluation-of-bone-repair-after-application-of-a-norbixin-membrane-scaffold-with-and-without-laser-photobiomodulation-%C3%AE-780-nm
#13
Adrielle Martins Monteiro Alves, Lílian Melo de Miranda Fortaleza, Antonio Luiz Martins Maia Filho, Danniel Cabral Leão Ferreira, Charllyton Luis Sena da Costa, Vicente Galber Freitas Viana, José Zilton Lima Verde Santos, Rauirys Alencar de Oliveira, Gustavo Oliveira de Meira Gusmão, Luís Eduardo Silva Soares
Biocompatible membranes are widely used in medicine to stimulate bone repair. Several studies have demonstrated that laser photobiomodulation (PBM) also stimulates osteoblast proliferation and osteogenesis at the fracture site, leading to a greater deposition of bone mass and accelerating the process of bone consolidation. This work assessed the therapeutic effect of 780-nm laser PBM and a polystyrene membrane coated with norbixin and collagen (PSNC) on bone healing in rats with calvarial bone defect. Histological staining, Raman spectroscopy, and scanning electron microscopy (SEM) were used to evaluate the bone repair process...
May 4, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29725946/spectrophotometric-photodynamic-diagnosis-of-prostate-cancer-cells-excreted-in-voided-urine-using-5-aminolevulinic-acid
#14
Yasushi Nakai, Makito Miyake, Satoshi Anai, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Sayuri Onisi, Nobumichi Tanaka, Kiyohide Fujimoto
To evaluate the feasibility of photodynamic diagnosis using 5-aminolevulinic acid (PDD-ALA) for detection of prostate cancer (PCa) cells in urine samples after prostate massage in patients who were suspected to have PCa. One hundred and eighty-nine patients with abnormal digital rectal examination and/or an elevated prostate-specific antigen (PSA) level who underwent initial prostate biopsy were recruited. After prostate massage, the first 60 mL of voided urine was collected. For PDD-ALA, 50 mL was used. The rest of collected urine was used for polymerase chain reaction (PCR) of PSA and glyceraldehyde 3-phosphate dehydrogenase (GAPDH)...
May 4, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29725945/low-level-laser-irradiation-modifies-the-effect-of-hyperglycemia-on-adhesion-molecule-levels
#15
Krzysztof Góralczyk, Justyna Szymańska, Łukasz Gryko, Jacek Fisz, Danuta Rość
Endothelium plays a key role in maintaining vascular homeostasis by secreting active factors involved in many biological processes such as hemostasis, angiogenesis, and inflammation. Hyperglycemia in diabetic patients causes dysfunction of endothelial cells. Soluble fractions of adhesion molecules like sE-selectin and vascular cell adhesion molecule (sVCAM) are considered as markers of endothelial damage. The low-level laser therapy (LLLT) effectively supports the conventional treatment of vascular complications in diabetes, for example hard-to-heal wounds in patients with diabetic foot syndrome...
May 3, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29725944/optical-coherence-tomography-to-evaluate-variance-in-the-extent-of-carious-lesions-in-depth
#16
Kyung-Jin Park, Hartmut Schneider, Dirk Ziebolz, Felix Krause, Rainer Haak
Evaluation of variance in the extent of carious lesions in depth at smooth surfaces within the same ICDAS code group using optical coherence tomography (OCT) in vitro and in vivo. (1) Verification/validation of OCT to assess non-cavitated caries: 13 human molars with ICDAS code 2 at smooth surfaces were imaged using OCT and light microscopy. Regions of interest (ROI) were categorized according to the depth of carious lesions. Agreement between histology and OCT was determined by unweighted Cohen's Kappa and Wilcoxon test...
May 3, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29717386/low-level-laser-irradiation-induces-a-transcriptional-myotube-like-profile-in-c2c12-myoblasts
#17
Juarez H Ferreira, Sarah S Cury, Ivan J Vechetti-Júnior, Geysson J Fernandez, Leonardo N Moraes, Carlos A B Alves, Paula P Freire, Carlos E A Freitas, Maeli Dal-Pai-Silva, Robson F Carvalho
Low-level laser irradiation (LLLI) has been used as a non-invasive method to improve muscular regeneration capability. However, the molecular mechanisms by which LLLI exerts these effects remain largely unknown. Here, we described global gene expression profiling analysis in C2C12 myoblasts after LLLI that identified 514 differentially expressed genes (DEG). Gene ontology and pathway analysis of the DEG revealed transcripts among categories related to cell cycle, ribosome biogenesis, response to stress, cell migration, and cell proliferation...
May 2, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29713842/effects-of-low-level-laser-therapy-on-soft-and-hard-tissue-healing-after-endodontic-surgery
#18
Revnak Metin, Ufuk Tatli, Burcu Evlice
The aim of this prospective study was to examine possible benefits of low-level laser therapy (LLLT) on soft and hard tissue healing after endodontic surgery. Seventy-six endo-surgery cases on maxillary incisors were included. The patients were assigned randomly into control and laser groups. In the laser group, gallium-aluminum-arsenide (GaAlAs) diode laser irradiation (810 nm, 129 mW, 3.87 J/cm2 ) was performed immediately after surgery and daily for postoperative 7 days from buccal and palatal surfaces (5 min for each side)...
April 30, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29713841/comparative-study-using-fractional-carbon-dioxide-laser-versus-glycolic-acid-peel-in-treatment-of-pseudo-acanthosis-nigricans
#19
N S Zaki, R F Hilal, R M Essam
Pseudo-acanthosis nigricans is a common dermatological disorder that is usually difficult to treat secondary to maceration of the skin from excessive sweating, obesity, or associated with endocrine disorders. Fractional photothermolysis and chemical peeling have been reported to improve the condition. To determine whether fractional CO2 laser resurfacing or glycolic acid peel is more effective and safe option for therapy. Twenty Egyptian patients were included in the study where each patient was subjected to three sessions of both fractional CO2 on the right side of the neck and glycolic acid peel 70% on the left side of the neck...
April 30, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29707756/comment-on-photobiomodulation-delays-the-onset-of-skeletal-muscle-fatigue-in-a-dose-dependent-manner
#20
LETTER
Thiago De Marchi
No abstract text is available yet for this article.
April 30, 2018: Lasers in Medical Science
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