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Seminars in Ophthalmology

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https://www.readbyqxmd.com/read/28402713/optical-biometry-derived-axial-length-measurements-following-intravitreal-anti-vascular-endothelial-growth-factor-treatment-for-macular-edema
#1
George D Kymionis, Athanassios Giarmoukakis, Ioanna K Apostolidi, Styliani V Blazaki, Konstantinos I Tsoulnaras, Joanna Moschandrea, Sofia Panagopoulou, Miltiadis K Tsilimbaris
PURPOSE: To evaluate axial length (AL) alterations in patients with macular disease over the course of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment. METHODS: In this prospective, comparative study, 33 patients with macular edema underwent unilaterally intravitreal anti-VEGF therapy and were followed for two months; the contralateral eyes were considered as controls. Central retinal thickness (CRT) was measured with spectral-domain optical coherence tomography and AL with an IOL-Master optical biometer...
April 12, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28394663/evaluation-of-choroidal-and-retinal-thickness-changes-in-parkinson-s-disease-using-spectral-domain-optical-coherence-tomography
#2
Marilita M Moschos, Irini P Chatziralli
PURPOSE: The purpose of this study was to evaluate retinal and choroidal thickness in patients with Parkinson's disease (PD) using spectral domain-optical coherence tomography (SD-OCT). MATERIAL AND METHODS: Participants in our study were 31 PD patients and 25 age-matched healthy controls. All participants underwent best-corrected visual acuity (BCVA) measurement, slit-lamp biomicroscopy, dilated fundoscopy, and SD-OCT. Macular and retinal nerve fiber layer (RNFL) thickness and choroidal thickness in all quadrants were recorded...
April 10, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28353369/cystoid-macular-edema-in-retinitis-pigmentosa-with-intermediate-uveitis-responded-well-to-oral-and-posterior-subtenon-steroid
#3
Koushik Tripathy
No abstract text is available yet for this article.
March 29, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28340314/ocular-manifestations-in-children-with-juvenile-onset-systemic-lupus-erythematosus
#4
Ghada Gawdat, Dina El-Fayoumi, Huda Marzouk, Yomna Farag
PURPOSE: To study the ocular manifestations of juvenile systemic lupus erythematosus (JSLE), including the ocular side-effects of the systemic medications used. METHODS: A descriptive cross-sectional study on 40 children diagnosed with JSLE was conducted. Ophthalmological and laboratory investigations as well as a calculation of the Systemic Lupus Disease Activity Index 2000 (SLEDAI-2K) were performed. RESULTS: Forty consecutive children, 32 females and 8 males, with JSLE were examined...
March 24, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28328294/microbiological-characteristics-and-clinical-outcomes-of-acinetobacter-spp-endophthalmitis-with-the-first-reported-case-of-acinetobacter-haemolyticus-endophthalmitis
#5
Mahima Jhingan, Divya Balakrishnan, Padmaja Kumari Rani, Mudit Tyagi, Joveeta Joseph
AIM: To present the microbiological details and clinical outcomes of Acinetobacter spp. endophthalmitis with the first reported case of A. haemolyticus. METHODS: A retrospective study of microbiologically proven Acinetobacter spp. endophthalmitis was carried out from 2010 to 2015. The data collected included age, type of endophthalmitis, best-corrected visual acuity (BCVA), species involved, and antibiotic susceptibility pattern. The primary outcomes measured were anatomical outcomes in terms of globe integrity and functional outcome as BCVA at last follow-up...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28328288/the-role-of-mf-erg-in-the-diagnosis-and-treatment-of-age-related-macular-degeneration-electrophysiological-features-of-amd
#6
Marilita M Moschos, Eirini Nitoda
INTRODUCTION: Age-related macular cegeneration (AMD) is the leading cause of visual dysfunction worldwide, affecting 9-25% of individuals between 65 and 75 years old. METHODS: We have reviewed the published articles investigating the role of multifocal electroretinogram (mf-ERG) in the diagnosis and treatment of AMD. RESULTS: Visual evoked potentials have revealed decreased amplitudes and higher latencies in patients with AMD, while the degeneration of photoreceptors and abnormalities of retinal pigment epithelium can be identified by electro-oculogram recordings...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28328282/frequency-of-erectile-dysfunction-in-males-with-central-serous-chorioretinopathy
#7
Ayse Balkarli, Muhammet Kazim Erol, Soner Yalcinkaya, Rumeysa Selvinaz Erol
OBJECTIVES: To evaluate the frequency of sexual dysfunction and associated factors in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: Fifty-eight CSCR patients who met the inclusion criteria and 99 age- and sex-matched healthy controls were prospectively investigated for sexual dysfunction and associated factors. All participants were investigated using the Beck Depression Inventory (BDI), Beck Anxiety Scale (BAS), and the15-question Index of Erectile Function-15 (IIEF-15) and by extensive examination of CSCR, associated factors, and confounding factors...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28296517/therapeutic-algorithm-for-congenital-ptosis-repair-with-levator-resection-and-frontalis-suspension-results-and-literature-review
#8
Riccardo Gazzola, Elena Piozzi, Luca Vaienti, Franz Wilhelm Baruffaldi Preis
BACKGROUND: Several treatments have been described for the treatment of congenital ptosis, but there are few studies that analyze the effectiveness of a therapeutic approach rather than a single technique. AIMS: In this study, we aim to evaluate the effectiveness of our therapeutic algorithm, which relies on levator muscle resection and frontalis suspension with silicone rods, polytetrafluoroethylene (PTFE), or autologous fascia lata. METHODS: We retrospectively analyzed all patients affected by congenital ptosis who underwent corrective surgery at a single department between January 1998 and January 2016...
March 15, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28287858/the-effect-of-pterygium-and-pterygium-surgery-on-corneal-biomechanics
#9
Mustafa Koç, Fuat Yavrum, Mehmet Murat Uzel, Emre Aydemir, Kemal Özülken, Pelin Yılmazbaş
PURPOSE: To evaluate the effect of pterygium and pterygium surgery on corneal biomechanics by ocular response analyzer (ORA, Reichert, USA). METHODS: This study considered 68 eyes (from 34 patients with a mean age of 21.2±7.1 years) with unilateral nasal, primary pterygium (horizontal length <4 mm), and having undergone pterygium excision and conjunctival autografting. Pterygium length and area were measured from a photograph of the anterior segment using Image J program...
March 13, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28272966/factors-to-be-considered-when-performing-cataract-surgery-in-patients-unable-to-recline-flat
#10
Aniko Rentka, Adam Kemeny-Beke
PURPOSE: Although phacoemulsification is routinely performed with the patient in a supine position, certain locomotor deformities and other severe ailments can lead to the inability of the patient to recline flat. METHODS: The present article surveys publications and summarizes our own experience regarding positioning techniques during cataract surgery on patients unable to adopt a supine position. RESULTS: The successful and effective performance of cataract surgery by phacoemulsification depend on the comfortable positioning of both the patient and the surgeon...
March 8, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28272971/the-influence-of-parental-myopia-on-children-s-myopia-in-different-generations-of-parent-offspring-pairs-in-south-korea
#11
Hyunmin Ahn, Il Suk Lyu, Tyler Hyungtaek Rim
PURPOSE: To compare the heritabilities of myopia and high myopia across three different generations in Korea. METHODS: Parent-offspring pairs of different age groups were included: two parents and their offspring aged 10-19 ("young families"), two parents and their offspring aged 20-29 ("middle-aged families"), and two parents and their offspring aged 30-45 ("older families") were selected from the 2008-2012 Korea National Health and Nutrition Examination Survey...
February 28, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28357886/clinical-appraisal-and-retinal-imaging-in-posterior-microphthalmos
#12
Kemal Tekin, Mehmet Yasin Teke, Mehmet Citirik
PURPOSE: To report a critical case series of five patients with posterior microphthalmos and the review of their clinical findings with the analyses of retinal imaging. METHOD: Case series. Complete ophthalmological examinations including optical coherence tomography (OCT) were evaluated. RESULTS: All patients had decreased visual acuity with high hyperopic refraction. Dilated fundus examination demonstrated that elevated papillomacular retinal folds with anterior segment were unremarkable...
February 15, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28165850/the-histopathological-findings-of-patients-who-underwent-blepharoplasty-due-to-dermatochalasis
#13
Ali Karnaz, Yasemin Aslan Katircioglu, Evin Singar Ozdemir, Pınar Celebli, Sema Hucumenoglu, Firdevs Ornek
PURPOSE: To assess changes in lymphatic vessels, collagen, and elastic fiber structure in excised tissues with dermatochalasis (DC). METHODS: In this prospective histopathological study, 70 upper eyelid skins of 35 patients operated on for dermatochalasis were compared with 10 eyelid skins of 10 patients operated on for other diagnoses. In histopathological examination, the two groups of patients were compared with respect to number of lymphatic vessels, largest lymphatic vessel diameter, number of elastic fibers, number of macrophages, edema between collagen fibers, and depth of stromal collagen bed...
February 6, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28060586/evidence-based-treatment-of-diabetic-macular-edema
#14
REVIEW
Rasha Barham, Hala El Rami, Jennifer K Sun, Paolo S Silva
Diabetes mellitus is a chronic disease that affects 415 million people worldwide. Despite treatment advances, diabetic eye disease remains a leading cause of vision loss worldwide. Diabetic macular edema (DME) is a common cause of vision loss in diabetic patients. The pathophysiology is complex and involves multiple pathways that ultimately lead to central retinal thickening and, if untreated, visual loss. First-line treatment of DME has evolved from focal/grid laser established by the Early Treatment of Diabetic Retinopathy Study (ETDRS) to intravitreous pharmacologic therapy...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27929728/editorial-retraction
#15
(no author information available yet)
No abstract text is available yet for this article.
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27929707/systemic-mineralocorticoid-antagonists-in-the-treatment-of-central-serous-chorioretinopathy
#16
REVIEW
Dong Yang, Dean Eliott
Central serous chorioretinopathy (CSCR) is a challenging disease characterized by subretinal serous fluid accumulation. The complex pathogenesis is still not fully understood, but is thought to be multifactorial and involves exogenous and endogenous factors affecting the choroid and retinal pigment epithelium. The involvement of corticosteroids is undisputed, while the contribution of mineralocorticoid pathways is under investigation. This review addresses the proposed pathogenesis models and the evidence for systemic treatment of CSCR with mineralocorticoid antagonists...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27805468/vision-testing-in-the-evaluation-of-concussion
#17
REVIEW
Cinthi Pillai, John W Gittinger
Traumatic brain injury results from an acute impact to the head causing brain dysfunction. Concussion is a form of mild traumatic brain injury. There are significant short- and long-term sequelae of concussion, and early diagnosis and management are key to recovery. Visual system symptoms and signs are common following concussion and have been shown to be a useful feature of concussion testing. Neuro-ophthalmic findings include abnormalities in the pupillary light reflex, accommodation, convergence, extraocular motility, steroacuity, as well as pursuit and saccades...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27805464/a-review-of-the-course-and-treatment-of-non-infectious-uveitis-during-pregnancy
#18
REVIEW
Lindsay A Grotting, George N Papaliodis
Inflammatory conditions such as autoimmune uveitis often occur in women of childbearing age. During pregnancy, women may experience exacerbations of their disease in the first trimester. In the later stages of pregnancy, however, the uveitis tends to remain less active. The management of uveitis during pregnancy is a challenging task, forcing the physician to re-evaluate the patient's current therapy and offer alternative options that pose the least risk to the patient and fetus. This article will review treatments widely used for uveitis, including corticosteroid therapy, anti-metabolites, calcineurin inhibitors, and biologic therapy...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27792450/attributes-associated-with-adherence-to-glaucoma-medical-therapy-and-its-effects-on-glaucoma-outcomes-an-evidence-based-review-and-potential-strategies-to-improve-adherence
#19
REVIEW
Arun Joseph, Louis R Pasquale
The treatment paradigm in glaucoma classically starts with exhausting all medical therapy prior to proceeding with laser or incisional surgery, although laser-first and surgery-first strategies have been explored in randomized clinical trials. Although glaucoma drops are proven to work well to lower intraocular pressure, slow the conversion from ocular hypertension, and slow the progression of disease in early open angle glaucoma, adherence to treatment is likely optimum in the randomized clinical trials that support these claims...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27792412/the-role-of-vitrectomy-in-the-management-of-fungal-endophthalmitis
#20
REVIEW
Yewlin E Chee, Dean Eliott
Fungal endophthalmitis is an important cause of vision loss worldwide with a large body of literature describing the treatment of the disease. The evidence supporting the use of pars plana vitrectomy in the management of fungal endophthalmitis is largely comprised of case reports and case series and demonstrates the important role of vitrectomy surgery. Vitrectomy can improve the likelihood of establishing the diagnosis, enhance the treatment of infection by removing fungal elements in the vitreous, aid in the removal of other inoculated intraocular structures, and is an important tool in the management of vision-threatening post-infectious sequelae like retinal detachment and epiretinal membrane...
2017: Seminars in Ophthalmology
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