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Seminars in Ophthalmology

Gena M Damento, Nelson S Winkler, David O Hodge, Sunil S Khanna, Cheryl L Khanna
PURPOSE: To determine the effect of a glaucoma team care model on resource utilization and efficiency in glaucoma management. METHODS: Retrospective cohort study of 358 patients diagnosed and treated for glaucoma. Analysis included number of patient visits, diagnostic tests, and glaucoma procedures performed before (2005-2007) and after (2008-2010) implementation of a team care model in 2008. Patients not involved in the model served as controls. RESULTS: Number of patient visits did not change significantly after model implementation (p > ...
September 21, 2018: Seminars in Ophthalmology
Snježana Kaštelan, Antonela Gverović-Antunica, Goran Pelčić, Marta Gotovac, Irena Marković, Boris Kasun
BACKGROUND AND METHODS: Diabetes mellitus is the most prevalent endocrinedisease in developed countries. In people with diabetes in addition to visionloss caused by diabetic retinopathy transient visual disturbances may occurfrequently caused by refractive changes. These changes in refraction are associated with variations in blood glucose levelsbut the underlying mechanism is still not fully understood. A systematic reviewwith a comprehensive literature search was performed in order to clarify the underlyingmechanisms regarding the connection of glycaemic control and refractive shift...
September 10, 2018: Seminars in Ophthalmology
Sevil Karaman Erdur, Goktug Demirci, Funda Dikkaya, Mehmet Selim Kocabora, Mustafa Ozsutcu
BACKGROUND: To determine the agreement of central corneal thickness (CCT) measurements taken with ultrasonic pachymetry (USP), spectral domain optical coherence tomography (SD-OCT) and noncontact specular microscopy (NSM). METHODS: A prospective, observational, cross-sectional study was performed in the outpatient ophthalmology clinic. CCT was measured in a total of 147 eyes of 147 consecutive healthy patients with USP, NSM, and SD-OCT. Same examiner performed all examinations...
March 6, 2018: Seminars in Ophthalmology
Mehmet Murat Uzel, Serdar Ozates, Mustafa Koc, Ayse Guzin Taslipinar Uzel, Pelin Yılmazbaş
PURPOSE: To assess the effect of posterior capsular opacification (PCO) and Neodymium-doped:Yttrium Aluminium Garnet (Nd:YAG) laser capsulotomy on tilt and decentration of intraocular lens (IOL) at vertical and horizontal meridians. METHODS: The study included 64 eyes of 64 patients. IOL decentration and tilt were measured using a Scheimpflug camera before and 1 month after Nd:YAG capsulotomy. Corrected distance visual acuity (CDVA) and manifest refraction were also determined...
February 27, 2018: Seminars in Ophthalmology
Robert Kromer, Julian Ueberschaar, Marc Schargus, Vasyl Druchkiv, Andreas Frings
We analyzed and quantified the 100 most frequently cited papers in macular imaging using optical coherence tomography (OCT). The databases of the Institute for Scientific Information databases utilized for identification of articles in macular imaging using OCT over the last 25 years since the introduction of OCT in ophthalmology. All articles containing "optical coherence tomography" and "retina" without "glaucoma". The publication dates of the 100 most-cited articles ranged from 1991 to 2015, with the greatest number of articles published in the 2000s, while the total number of citations per article was greatest for articles published in the 1990s...
February 26, 2018: Seminars in Ophthalmology
Kamran Rahmatnejad, Jonathan S Myers, Megan E Falls, Sarah R Myers, Michael Waisbourd, Lisa A Hark
PURPOSE: To determine what metrics might impact satisfaction survey responses. METHODS: A 37-question survey was administered to 249 participants. Responses were correlated to demographics, clinical factors, weather conditions, and examination timing. RESULTS: Sample consists of 55.4% female and 73.9% white, and mean age was 65.1 years. Participants were assigned to: completely satisfied (77.9%) or not completely satisfied (22.1%) groups based on their rating of glaucoma specialist on a scale of 1-10, while 10 considered "completely satisfied" and less than 10 "not completely satisfied...
January 17, 2018: Seminars in Ophthalmology
Hidenaga Kobashi, Kazutaka Kamiya, Kimiya Shimizu
PURPOSE: To assess the relationship of forward and backward scattering and corneal higher-order aberrations (HOAs) with corrected distance visual acuity (CDVA) after penetrating keratoplasty (PK). METHODS: This retrospective study comprised 25 eyes of 25 consecutive patients who underwent PK using the VisuMax femtosecond laser system and age-matched 25 eyes of 25 healthy subjects. We quantitatively assessed objective scattering index (OSI) using the double-pass instrument (OQAS II, Visiometrics), corneal densitometry (CD) and corneal HOAs with the Scheimpflug rotating camera (Pentacam HR, Oculus) 1 year postoperatively...
January 16, 2018: Seminars in Ophthalmology
Jae Hui Kim, Young Suk Chang, Jong Woo Kim, Chul Gu Kim, Dong Won Lee
PURPOSE: To evaluate the incidence of early recurrent hemorrhage in submacular hemorrhage secondary to type 3 neovascularization or retinal angiomatous proliferation (RAP) and its influence on visual prognosis. METHODS: This retrospective study included 32 eyes with submacular hemorrhage secondary to type 3 neovascularization or RAP that underwent anti-vascular endothelial growth factor (VEGF) therapy. The eyes exhibiting an increase in the extent of hemorrhage within 6 months after hemorrhage development were included in the early recurrent hemorrhage group, and the remaining eyes were included in the non-early recurrent hemorrhage group...
2018: Seminars in Ophthalmology
Kohta Fujiwara, Miho Yasuda, Jun Hata, Yuji Oshima, Sawako Hashimoto, Takeshi Yoshitomi, Yutaka Kiyohara, Tatsuro Ishibashi, Toshiharu Ninomiya, Koh-Hei Sonoda
PURPOSE: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. METHODS: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings...
2018: Seminars in Ophthalmology
Onsiri Thanathanee, Rawipaparas Pulnitiporn, Orapin Anutarapongpan, Olan Suwan-Apichon, Chavakij Bhoomibunchoo
PURPOSE: To compare the bacterial cultures of the lower eyelid margins and lower fornices between ocular irrigations with and without eyelid margin cleaning before intraocular surgery. METHODS: A prospective study was carried out that included 102 eyes from 51 patients undergoing intraocular surgery between December 2016 and April 2017. In each patient, the surgical eye (control group) only received ocular irrigation and the opposite eye (study group) received ocular irrigation with eyelid margin cleaning...
2018: Seminars in Ophthalmology
Benjamin P Nicholson, Amrou M Ali Idris, Sophie J Bakri
PURPOSE: Retrospective cohort study to identify clinical characteristics associated with poor visual acuity in central serous chorioretinopathy (CSC). MATERIALS AND METHODS: Charts of patients in a tertiary referral clinic diagnosed with CSC over a 13-year period were reviewed. Multivariate logistic regression analyses were performed to assess the relationship between several clinical characteristics and final visual acuity. RESULTS: Of 353 subjects with CSC, 258 had a minimum of 2 clinical assessments and adequate follow-up...
2018: Seminars in Ophthalmology
Koushik Tripathy, Rohan Chawla, Shreyas Temkar, Pradeep Sagar, Seema Kashyap, Neelam Pushker, Yog Raj Sharma
Phthisis bulbi denotes end-stage eye disease characterized by shrinkage and disorganization of the eye with the resultant functional loss. The major factors associated with the pathogenesis of phthisis are hypotony, deranged blood-ocular barriers, and inflammation. Common causes include trauma, surgery, infection, inflammation, malignancy, retinal detachment, and vascular lesions. A phthisical globe shows a small squared off shape, opaque and thickened cornea, thickened sclera, neovascularization of iris, cataract, cyclitic membrane, ciliochoroidal detachment, and retinal detachment...
2018: Seminars in Ophthalmology
Aubrey L Gilbert, Bart Chwalisz, Robert Mallery
There are a number of surgical options for treatment of idiopathic intracranial hypertension (IIH) when it is refractory to medical treatment and weight loss. Optic nerve sheath fenestration (ONSF) is one of these options. Use of this procedure varies among centers due to experience with the procedure and concern for associated complications that can result in severe loss of vision. This review summarizes the literature concerning post-surgical complications of ONSF for IIH.
2018: Seminars in Ophthalmology
Aditi Gupta, Jennifer K Sun, Paolo S Silva
Intravitreous injections are presently the second most frequently performed ophthalmic procedure and the most common vitreoretinal procedure. In diabetic patients, intravitreous injections are frequently performed for the treatment of center-involved diabetic macular edema, proliferative diabetic retinopathy, or other co-existing retinal vascular disease. Diabetic patients may be at higher risk of adverse events compared to non-diabetic individuals, given frequent systemic comorbidities, such as cardiovascular and renal disease and increased susceptibility to infection...
2018: Seminars in Ophthalmology
Rishikesh Kumar Gupta, Inderjeet Kaur, Tapas C Nag, Jay Chhablani
The electron microscopy techniques were used in various fields as an analytical technique under in vitro conditions, which provides the sufficient resolution for better visualization and interpretation. This review gives a brief overview of the analytical application of transmission electron microscopy (TEM) and scanning electron microscopy (SEM) techniques and critical findings in different retinal pathologies. This review article aims to improvise understanding of retinal microstructures for clinicians which will help to improve the interpretation of the current advanced imaging techniques...
2018: Seminars in Ophthalmology
Yui Tobimatsu, Noriko Inada, Jun Shoji, Satoru Yamagami
PURPOSE: To retrospectively investigate the clinical characteristics of Moraxella keratitis. PATIENTS AND METHODS: We reviewed the medical records of 17 patients with Moraxella keratitis. Onset age, sex, predisposing factors, initial clinical presentations, culture and antimicrobial susceptibility testing, and management and outcome of medical treatment were investigated. RESULT: Moraxella keratitis was more common in patients older than 40 years of age, and its representative initial presentation was a round-shaped ulcer with endothelial plaque (70...
2018: Seminars in Ophthalmology
Muhammed Altinisik, Arif Koytak, Ahmet Elbay, Enes Toklu, Taha Sezer, Abdurrahim Kocyigit
PURPOSE: To analyze oxidative stress parameters in the aqueous humor with retinal vein occlusion. MATERIALS AND METHODS: A total of 56 patients who underwent cataract surgery were enrolled in this study. The eyes with retinal vein occlusion were included in the study group. Aqueous humor was sampled from all patients and analyzed by an automated measurement method. Total oxidant status (TOS), total antioxidant status (TAS), and oxidative stres index (OSI) were calculated...
2018: Seminars in Ophthalmology
Asmaa Mohamed Ibrahim, Sameh Mohamed Elgouhary, Moustafa Kamal Nassar, Ahmed Helmy El Batanony
OBJECTIVE: The aim of this study is to compare subfoveal choroidal thickness (SFCT) before and after uneventful phacoemulsification using enhanced depth imaging optical coherence tomography (EDI-OCT). BACKGROUND: Cataract is a major cause of visual impairment in the elderly. Cataract surgery is the most common ophthalmic surgery and is performed simultaneously with glaucoma or vitreous surgery in many cases. However, according to the results in epidemiology studies, cataract surgery is associated with the onset of age-related macular degeneration (AMD) and cataract surgery increases visual acuity in these patients without an increased risk of progression to exudative AMD...
2018: Seminars in Ophthalmology
Aparna Rao, Sarada Prasanna Sarangi, Debananda Padhy, Niranjan Raj, Gopinath Das
PURPOSE: To investigate and compare the visual field performance following three different types of visual field instruction strategies. METHOD: Ninety consecutive visual field-naïve glaucoma patients who can perform the test and understand instructions were imparted three forms of instructions prior to the visual field test. Patients with visual acuity <20/200, central corneal opacities, or anterior segment pathology and patients unable to understand general instructions/uncooperative were excluded...
2018: Seminars in Ophthalmology
Darija Jurišić, Mia Zorić Geber, Ivan Ćavar, Dobrila Karlica Utrobičić
This study aimed to investigate the influence of silicone oil on the retinal nerve fiber layer (RNFL) thickness in patients with primary rhegmatogenous retinal detachment who underwent vitreoretinal surgery. The study included 47 patients (eyes), who underwent a pars plana vitrectomy with the silicone oil tamponade. The control group included unoperated eye of all participants. Spectral-domain optical coherence tomography (SD-OCT) was used for the measurements of peripapilar and macular RNFL thickness. The average peripapillary RNFL thickness was significantly higher in the silicone oil filled eyes during endotamponade and after its removal...
2018: Seminars in Ophthalmology
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