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Journal of Critical Care

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https://www.readbyqxmd.com/read/28641231/association-between-timing-of-intubation-and-outcome-in-critically-ill-patients-a-secondary-analysis-of-the-icon-audit
#1
Philippe R Bauer, Ognjen Gajic, Rahul Nanchal, Rahul Kashyap, Ignacio Martin-Loeches, Yasser Sakr, Stephan M Jakob, Bruno François, Xavier Wittebole, Richard G Wunderink, Jean-Louis Vincent
PURPOSE: The optimal timing of endotracheal intubation in critically ill patients requiring invasive mechanical ventilation remains undefined. MATERIAL AND METHODS: In a secondary analysis of the large, prospective ICON database, we used a piecewise proportional hazards model to compare outcomes in patients who underwent intubation early (within two days after intensive care unit [ICU] admission) or later. RESULTS: After excluding 5340 patients already intubated on admission or with therapeutic limitation, 4729 patients were analyzed, of whom 4074 never underwent intubation...
June 16, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28637588/is-artificial-neural-network-an-ideal-modelling-technique
#2
LETTER
Sabri Özden, Baris Saylam, Mesut Tez
No abstract text is available yet for this article.
June 16, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28629868/reply-about-letter-regarding-prevalence-of-graduated-compression-stocking-associated-pressure-injuries-in-surgical-intensive-care-units
#3
LETTER
Jonathan K Aboagye, Deborah B Hobson, Brandyn D Lau, Dauryne L Shaffer, Peggy S Kraus, Michael B Streiff, Elliott R Haut
No abstract text is available yet for this article.
June 10, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28625544/sepseast-bridging-between-east-and-west
#4
EDITORIAL
Zsolt Molnar
No abstract text is available yet for this article.
June 9, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28622641/u-s-drug-shortages-for-medications-used-in-adult-critical-care-2001-2016
#5
Maryann Mazer-Amirshahi, Munish Goyal, Suleman A Umar, Erin R Fox, Mark Zocchi, Kristy L Hawley, Jesse M Pines
PURPOSE: We describe trends in U.S. shortages impacting critical care drugs from 2001 to 2016. MATERIALS AND METHODS: Shortages within the scope of critical care were identified using data from the University of Utah Drug Information Services. Shortage characteristics were described using standard descriptive statistics and regression analysis. RESULTS: Of 1969 shortages reported, 1004 (51%) were for drugs used in critical care. New shortages fell from 2001 to 2004, then increased, peaking in 2011 (116)...
June 9, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28614762/intra-abdominal-hypertension-and-abdominal-compartment-syndrome-in-pediatrics-a-review
#6
REVIEW
Farah Chedly Thabet, Janeth Chiaka Ejike
PURPOSE: To consolidate pediatric intensivists' understanding of the pathophysiology, definition, incidence, monitoring, and management of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS); and to highlight the characteristics related to the pediatric population. METHODS: This is a narrative review article that utilized a systematic search of the medical literature published in the English language between January 1990 and august 2016. Studies were identified by conducting a comprehensive search of Pub Med databases...
June 7, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28599990/evaluation-of-the-feasibility-of-average-volume-assured-pressure-support-ventilation-in-the-treatment-of-acute-hypercapnic-respiratory-failure-associated-with-chronic-obstructive-pulmonary-disease-a-pilot-study
#7
LETTER
https://www.readbyqxmd.com/read/28601350/response-to-the-letter-to-the-editor
#8
E M J Durlinger, A M E Spoelstra-de Man, Y M Smulders
No abstract text is available yet for this article.
June 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28599198/hypoalbuminemia-systemic-inflammatory-response-syndrome-and-functional-outcome-in-intracerebral-hemorrhage
#9
Mario Di Napoli, Réza Behrouz, Christopher H Topel, Vivek Misra, Fulvio Pomero, Alessia Giraudo, Paolo Pennati, Luca Masotti, Floris H B M Schreuder, Julie Staals, Catharina J M Klijn, Craig J Smith, Adrian R Parry-Jones, Mark A Slevin, Brian Silver, Joshua Z Willey, Mahmoud R Azarpazhooh, Jaime Masjuán Vallejo, Hipólito Nzwalo, Aurel Popa-Wagner, Daniel A Godoy
PURPOSE: Hypoalbuminemia and systemic inflammatory response syndrome (SIRS) are reported in critically-ill patients, but their relationship is unclear. We sought to determine the association of admission serum albumin and SIRS with outcomes in patients with intracerebral hemorrhage (ICH). METHODS: We used a multicenter, multinational registry of ICH patients to select patients in whom SIRS parameters and serum albumin levels had been determined on admission. Hypoalbuminemia was defined as the lowest standardized quartile of albumin; SIRS according to standard criteria...
June 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28595082/a-retrospective-analysis-of-the-effectiveness-of-antipsychotics-in-the-treatment-of-icu-delirium
#10
Cory B Weaver, Sandra L Kane-Gill, Scott R Gunn, Levent Kirisci, Pamela L Smithburger
PURPOSE: Conflicting data exists on the efficacy of antipsychotics for treatment of intensive care unit (ICU) delirium. The purpose of this study was to compare time to delirium resolution for ICU patients who were managed with and without antipsychotics. MATERIALS AND METHODS: This retrospective cohort evaluation included patients admitted to 12 ICUs at 5 sites over 5 weeks diagnosed with delirium. The primary outcome was time to delirium resolution. Secondary outcomes included ICU length of stay (LOS), mortality, discharge disposition and delirium redevelopment...
June 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28592360/clinical-study-of-a-new-modified-early-warning-system-scoring-system-some-lingering-doubts
#11
Xianshi Zhou, Ye Ye, Guanghua Tang
No abstract text is available yet for this article.
June 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28591679/serial-blood-lactate-measurements-and-its-prognostic-significance-in-intensive-care-unit-management-of-aneurysmal-subarachnoid-hemorrhage-patients
#12
Tomoya Okazaki, Toru Hifumi, Kenya Kawakita, Hajime Shishido, Daisuke Ogawa, Masanobu Okauchi, Atsushi Shindo, Masahiko Kawanishi, Shigeaki Inoue, Takashi Tamiya, Yasuhiro Kuroda
PURPOSE: This study assesses the behavior of serial blood lactate measurements during intensive care unit (ICU) stay to identify prognostic factors of unfavorable neurological outcomes (UO) in patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS: We retrospectively reviewed all patients who were consecutively hospitalized with SAH between 2009 and 2016. Arterial blood lactate levels were routinely obtained on admission and every 6h in the ICU. Univariate/multivariate analyses were performed to identify independent predictors of UO (modified Rankin scale of 3-6 upon hospital discharge)...
June 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28595083/therapeutic-effect-of-beta-blocker-in-patients-with-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#13
Zaifeng Chen, Linjun Tang, Xinlong Xu, Xiaojie Wei, Lutong Wen, Qingsong Xie
OBJECTIVE: β-Blocker exposure has been shown to reduce mortality in traumatic brain injury (TBI); however, the efficacy of β-blockers remains inconclusive. Therefore, a meta-analysis was conducted in this paper to evaluate the safety and efficacy of β-blocker therapy on patients with TBI. METHODS: The electronic databases were systemically retrieved from construction to February 2017. The odds ratio (OR), mean difference (MD) and 95% confidence intervals (CI) were determined...
May 31, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28599199/the-haemodynamic-effects-of-bolus-versus-slower-infusion-of-intravenous-crystalloid-in-healthy-volunteers
#14
Ida F Ukor, Andrew K Hilton, Michael J Bailey, Rinaldo Bellomo
PURPOSE: This pilot study aimed to characterise the haemodynamic effect of 1L of IV normal saline (NS) administered as a rapid versus slow infusion on cardiac output (CO), heart rate (HR), systemic blood pressures, and carotid blood flow in six healthy volunteers. MATERIALS AND METHODS: Six healthy male volunteers aged 18-65years were randomized to receive 1L NS given over 30min or 120min. On a subsequent study session the alternate fluid regimen was administered...
May 30, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28599200/assessment-of-mechanically-ventilated-patients-intoxicated-with-organophosphates-by-a-novel-surface-electromyographic-index
#15
María Bernarda Salazar Sánchez, Alher Mauricio Hernández Valdivieso, Miguel Ángel Mañanas Villanueva
PURPOSE: We present a new electromyographic index, named Engagement of Respiratory Muscle (ERM), for assessing the level of participation of respiratory muscles during spontaneous breathing test in patients poisoned with organophosphorus compound. METHODS: Diaphragm and sternocleidomastoid muscles activity was recorded by surface electromyography during spontaneous breathing test. A population of 23 patients poisoned with organophosphates and mechanically ventilated, and a control group of 28 healthy subjects were analyzed...
May 29, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28583415/the-pseudo-normalization-of-the-ratio-index-of-the-venous-to-arterial-co2-tension-difference-to-the-arterial-central-venous-o2-difference-in-hypoxemia
#16
LETTER
Huaiwu He, Dawei Liu
No abstract text is available yet for this article.
May 29, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28583414/mortality-length-of-stay-bloodstream-and-respiratory-viral-infections-in-a-pediatric-intensive-care-unit-comment-on-data-sparsity
#17
LETTER
Erfan Ayubi, Saeid Safiri
No abstract text is available yet for this article.
May 28, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28591678/treatment-outcomes-after-implementation-of-an-adapted-who-protocol-for-severe-sepsis-and-septic-shock-in-haiti
#18
Alfred Papali, T Eoin West, Avelino C Verceles, Marc E Augustin, L Nathalie Colas, Carl H Jean-Francois, Devang M Patel, Nevins W Todd, Michael T McCurdy
PURPOSE: The World Health Organization (WHO) has developed a simplified algorithm specific to resource-limited settings for the treatment of severe sepsis emphasizing early fluids and antibiotics. However, this protocol's clinical effectiveness is unknown. We describe patient outcomes before and after implementation of an adapted WHO severe sepsis protocol at a community hospital in Haiti. MATERIALS AND METHODS: Using a before-and-after study design, we retrospectively enrolled 99 adult Emergency Department patients with severe sepsis from January through March 2012...
May 27, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28601043/pediatric-intermediate-care-and-pediatric-intensive-care-units-picu-metrics-and-an-analysis-of-patients-that-use-both
#19
Andrew S Geneslaw, Haomiao Jia, Adam R Lucas, Michael S D Agus, Jeffrey D Edwards
PURPOSE: To examine how intermediate care units (IMCUs) are used in relation to pediatric intensive care units (PICUs), characterize PICU patients that utilize IMCUs, and estimate the impact of IMCUs on PICU metrics. MATERIALS & METHODS: Retrospective study of PICU patients discharged from 108 hospitals from 2009 to 2011. Patients admitted from or discharged to IMCUs were characterized. We explored the relationships between having an IMCU and several PICU metrics: physical length-of-stay (LOS), medical LOS, discharge wait time, admission severity of illness, unplanned PICU admissions from wards, and early PICU readmissions...
May 26, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28577477/is-gut-feeling-by-medical-staff-better-than-validated-scores-in-estimation-of-mortality-in-a-medical-intensive-care-unit-the-prospective-feeling-on-icu-study
#20
Anne Radtke, Roman Pfister, Kathrin Kuhr, Matthias Kochanek, Guido Michels
PURPOSE: The aim of the FEELING-ON-ICU study was to compare mortality estimations of critically ill patients based on 'gut feeling' of medical staff and by Acute Physiology And Chronic Health Evaluation (APACHE) II, Simplified Acute Physiology Score (SAPS) II and Sequential Organ Failure Assessment (SOFA). MATERIALS AND METHODS: Medical staff estimated patients' mortality risks via questionnaires. APACHE II, SAPS II and SOFA were calculated retrospectively from records...
May 25, 2017: Journal of Critical Care
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