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Journal of Gastroenterology and Hepatology

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https://www.readbyqxmd.com/read/29791723/functional-and-morphological-recovery-is-incomplete-after-acute-and-acute-recurrent-pancreatitis-in-children
#1
Srikanth Puttaiah Kadyada, Babu Ram Thapa, Karanvir Kaushal, Rama Walia, S V Rana, Narendra Dhaka, Sadhna B Lal, Rajendra Prasad, Subhamoy Das, Rajini Thakur, Kishore Kamal
OBJECTIVE: There is lack of data on functional and morphological recovery after an attack of acute pancreatitis (AP) or acute recurrent pancreatitis (ARP) in children. This study aims to evaluate the functional impairment and morphological changes in the pancreas after recovery. METHODS: All consecutive patients presenting with AP (n=61) or ARP (n=35), as per standard diagnostic criteria were enrolled. After 2 months of pancreatitis, fecal elastase-1(μg/g) and 2-hour oral glucose tolerance test to calculate oral disposition index (DIo )mmol/L-1 (beta cell function) were done...
May 23, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29791059/the-use-of-high-resolution-colonic-manometry-to-establish-etiology-and-direct-treatment-in-patients-with-constipation-case-series-with-correlation-to-histology
#2
Yuwei Li, Jiying Cong, Fei Fei, Zhao Zhang, Yongjun Yu, Chen Xu, Xipeng Zhang, Shiwu Zhang
BACKGROUND AND AIM: Different clinical treatments are available to treat patients with constipation. We aimed to study the etiology and direct treatment in a case series of patients with constipation by the use of high-resolution colonic manometry (HRCM). METHODS: HRCM was used to record the colorectal peristaltic contractions of the entire colon in patients. Based on the results of HRCM, 151 patients with constipation were classified into groups and received different clinical treatment such as a total or subtotal colectomy, local excision, or conservative treatment...
May 23, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29791048/long-term-course-of-inflammatory-bowel-disease-after-the-great-east-japan-earthquake
#3
Teruko Miyazawa, Hisashi Shiga, Yoshitaka Kinouchi, Seiichi Takahashi, Gen Tominaga, Hiroki Takahashi, Sho Takagi, Nobuya Obana, Tatsuya Kikuchi, Shinya Omori, Yuichirou Sato, Shuichiro Takahashi, Ken Umemura, Katsuya Endo, Yoichi Kakuta, Masaki Matsuura, Tomoya Kimura, Masatake Kuroha, Tooru Shimosegawa
BACKGROUND AND AIM: This study analyzed inflammatory bowel disease activity for two years after the Great East Japan Earthquake. METHODS: We compared the relapse rates of patients with ulcerative colitis or Crohn's disease 1 and 2 years after the earthquake with rates immediately after the earthquake. To evaluate continuous disease courses, we also performed multivariate time-to-event analyses from the time of the earthquake to the onset of additional treatments...
May 23, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29767452/adenoma-of-colorectal-laterally-spreading-tumor-non-granular-type-with-biological-phenotypic-features-similar-to-cancer
#4
Kengo Nagai, Yoshito Hayashi, Keiichiro Honma, Akihiko Sakatani, Shunsuke Yoshii, Tetsuji Fujinaga, Akira Maekawa, Yoshiki Tsujii, Satoshi Hiyama, Shinichiro Shinzaki, Kenji Watabe, Hideki Iijima, Masahiko Tsujii, Tsunekazu Mizushima, Eiichi Morii, Tetsuo Takehara
BACKGROUND AND AIM: Colorectal laterally spreading tumors (LST) are morphologically subdivided into granular (LST-G) and non-granular (LST-NG) categories. We aimed to elucidate the differences in oncogenic characteristics between the two types. METHODS: LST resected by endoscopic submucosal dissection and surgery from March 2009 to May 2017 were examined for p53-positivity, Ki-67 labeling index (LI), microvessel density, degree of fibrosis, intensities of inducible nitric oxide synthase (iNOS) and nitrotyrosine (NT), and expression of acid mucins...
May 16, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29767442/hepatobiliary-and-pancreatic-intrahepatic-cholangiocarcinoma-with-distant-cutaneous-metastases-to-the-face
#5
M K Kang, E J Goo, S B Kim, K H Kim, T N Kim
No abstract text is available yet for this article.
May 16, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29761833/hepatobiliary-and-pancreatic-pancreatic-cancer-with-elevated-serum-igg4-level-due-to-multiple-myeloma-mimicking-localized-autoimmune-pancreatitis
#6
S Kato, M Kuwatani, K Kawakubo, R Sugiura, K Hirata, S Tanikawa, T Mitsuhashi, S Shiratori, N Sakamoto
No abstract text is available yet for this article.
May 15, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29744928/parasutterella-in-associated-with-irritable-bowel-syndrome-and-intestinal-chronic-inflammation
#7
Yan-Jie Chen, Hao Wu, Sheng-Di Wu, Nan Lu, Yi-Ting Wang, Hai-Ning Liu, Ling Dong, Tao-Tao Liu, Xi-Zhong Shen
BACKGROUND AND AIM: Irritable bowel syndrome (IBS) is a highly prevalent chronic functional gastrointestinal disorder. Recent studies have showed increasing important role of gut microbiota in the pathophysiological changes of IBS. Our study aims to elaborate the association between intestinal flora with the genesis and the development of IBS. METHODS: Illumina high-throughput sequencing technology was applied to investigate microbial communities of IBS patients and healthy donors...
May 9, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29744922/substitutions-in-interferon-sensitivity-determining-region-and-hepatocarcinogenesis-after-hepatitis-c-virus-eradication
#8
Satoshi Yasuda, Masatoshi Ishigami, Yoji Ishizu, Teiji Kuzuya, Takashi Honda, Kazuhiko Hayashi, Hidenori Toyoda, Takashi Kumada, Yoshiki Hirooka, Hidemi Goto
BACKGROUND AND AIM: Amino acid substitutions in the interferon sensitivity determining region (ISDR) within the NS5A region are known to be associated with responsiveness to interferon (IFN) based therapy. Additionally, previous studies reported that the ISDR was related to the development of hepatocellular carcinoma (HCC) in patients infected with hepatitis C virus (HCV). However, the association between substitutions in the ISDR and the development of HCC in patients who achieved sustained virological response (SVR) is unclear...
May 9, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29737582/wisteria-floribunda-agglutinin-positive-human-mac-2-binding-protein-in-decompensated-cirrhosis
#9
Haruki Uojima, Hisashi Hidaka, Yoshiaki Tanaka, Tomoyoshi Inoue, Mie Onoue, Naohisa Wada, Kousuke Kubota, Takahide Nakazawa, Akitaka Shibuya, Tomoaki Fujikawa, Tsuyoshi Nakayama, Hiroki Yamanoue, Ji Hyun Sung, Makoto Kako, Wasaburo Koizumi
BACKGROUND AND AIM: An assay for Wisteria floribunda agglutinin-positive human Mac-2 binding protein (WFA+ -M2BP) has been reported as a useful non-invasive marker for the evaluation of the staging of fibrosis in several chronic liver diseases. However, available data on the effect of WFA+ -M2BP level in decompensated cirrhosis patients was limited. It is important that these investigations can validate the diagnostic utility of WFA+ -M2BP in the full range of patients with liver cirrhosis...
May 8, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29737561/cryoglobulinemia-is-associated-with-advanced-liver-fibrosis-in-chronic-hepatitis-c-patients
#10
Batbold Batsaikhan, Ching-I Huang, Ming-Lun Yeh, Chung-Feng Huang, Po-Cheng Liang, Ming-Yen Hsieh, Jee-Fu Huang, Ming-Lung Yu, Wan-Long Chuang, Jin-Ching Lee, Pei-Lun Lee, Chia-Yen Dai
BACKGROUND AND AIM: The prevalence of mixed cryoglobulinemia (MC) is 15-50% in chronic hepatitis C (CHC) patients and these patients are in an increased risk of liver fibrosis and cirrhosis, but it is controversial. We aimed to reveal the prevalence of MC in Asian population and to determine the relationship between presence of serum cryoglobulinemia and liver fibrosis in CHC patients with or without liver biopsy. METHODS: Totally 2255 treatment naïve patients retrospectively enrolled in our study...
May 8, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29736946/accuracy-of-liver-stiffness-spleen-stiffness-and-ls-spleen-diameter-to-platelet-ratio-score-in-detection-of-esophageal-varices-systemic-review-and-meta-analysis
#11
Wuttiporn Manatsathit, Hrishikesh Samant, Saurabh Kapur, Thammasin Ingviya, Mohammad Esmadi, Karn Wijarnpreecha, Timothy McCashland
BACKGROUND: There is increasing evidence of non-invasive measurement using elastography such liver stiffness (LS), spleen stiffness (SS), and LS-spleen diameter to platelet ratio score (LSPS) for detection of esophageal varices (EV); however, data regarding comparison between these three parameters are limited. METHODS: We performed a systemic review and meta-analysis of studies evaluating performance of LS, SS, and LSPS for detection of EV and high risk/clinically significant EV (HREV)...
May 8, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29707809/hepatobiliary-and-pancreatic-nivolumab-related-cholangiopathy
#12
C Hamoir, M de Vos, F Clinckart, G Nicaise, M Komuta, N Lanthier
No abstract text is available yet for this article.
April 29, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29697855/consensus-and-contentious-statements-on-the-use-of-probiotics-in-clinical-practice-a-south-east-asian-gastro-neuro-motility-association-working-team-report
#13
REVIEW
Kok-Ann Gwee, Warren Wei-Rhen Lee, Khoon Lin Ling, Choon Jin Ooi, Seng Hock Quak, Yock Young Dan, Kewin Tien-Ho Siah, James Guoxian Huang, Andrew Seng Boon Chua, Ida Normiha Hilmi, R A Raja Affendi, Christina Ong, Marcellus Simadibrata, Murdani Abdullah, Jose D Sollano, Somchai Leelakusolvong, Sutep Gonlachanvit, Yeong Yeh Lee, Jane D Ricaforte-Campos, Yee Kian Yin, Kuck-Meng Chong, Chong Yuen Wong
The concept of consuming microorganisms in the treatment of a medical condition and in health maintenance has gained much traction, giving rise to an abundance of medical claims, and of health supplements. We identified relevant clinical questions on the therapeutic use of probiotics and reviewed the literature in irritable bowel syndrome, inflammatory bowel disease, impaired intestinal immunity, liver disease, intestinal infections and common childhood digestive disorders. Statements were developed to address these clinical questions...
April 26, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29697158/safety-and-efficacy-of-antibiotics-among-acutely-decompensated-cirrhosis-patients
#14
Shahid Habib, Nehali Patel, Sandeep Yarlagadda, Chiu-Hsieh Hsu, Sarah Patel, Lindsey Schader, Courtney Walker, Innocent Twesigye
BACKGROUND AND AIM: Infection is a leading precipitant of acute-on-chronic liver failure. We aim to determine the safety and efficacy of antibiotics within acute-on-chronic liver failure. METHODS: Retrospective study of 457 acute-on-chronic liver failure patients, admitted to the University of Arizona Health Network between January 1 and December 31, 2014. Eligibility criteria were: at least 18 years of age and six months follow-up, data available to calculate systemic inflammatory response syndrome, and acute-on-chronic liver failure...
April 26, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29697157/the-association-between-pancreatic-fat-and-incidence-of-metabolic-syndrome-a-5-year-japanese-cohort-study
#15
Hajime Yamazaki, Shinichi Tauchi, Miho Kimachi, Mitsuru Dohke, Nagisa Hanawa, Yoshihisa Kodama, Akio Katanuma, Yosuke Yamamoto, Shingo Fukuma, Shunichi Fukuhara
BACKGROUND AND AIM: Previous cross-sectional studies showed that pancreatic fat was associated with metabolic syndrome. However, no longitudinal study has evaluated whether people with high pancreatic fat are likely to develop future metabolic syndrome. We investigated the association between baseline pancreatic fat and metabolic syndrome incidence. METHODS: In 2008-2009, 320 participants without metabolic syndrome underwent health checks, which included unenhanced computed tomography (CT), and were followed up annually for 4-5 years...
April 26, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29691909/hepatobiliary-and-pancreatic-segmental-arterial-mediolysis-of-pancreaticoduodenal-artery-accompanied-by-acute-pancreatitis-and-duodenal-obstruction
#16
Y Shiraishi, K Imai, Y-I Yamashita, Y Nakao, S Nakagawa, H Okabe, H Nitta, A Chikamoto, H Baba
No abstract text is available yet for this article.
April 24, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29691905/hepatobiliary-and-pancreatic-obliterative-portal-venopathy-found-in-castleman-disease-variant-of-poems-syndrome
#17
L Zhang, H Gao, Y Feng, G Wang, X Zhang, Z Li
No abstract text is available yet for this article.
April 24, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29691898/gastrointestinal-ct-and-pet-ct-imaging-of-splenic-littoral-cell-angiosarcoma
#18
B D Nguyen
No abstract text is available yet for this article.
April 24, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29691897/hepatobiliary-and-pancreatic-rare-hepatic-vascular-tumor-presenting-with-hypertrophic-osteoarthropathy
#19
H Caterson, K Liu
No abstract text is available yet for this article.
April 24, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29672926/insights-into-the-etiology-associated-gene-regulatory-networks-in-hepatocellular-carcinoma-from-the-cancer-genome-atlas
#20
Veerabrahma Pratap Seshachalam, Karthik Sekar, Kam M Hui
BACKGROUND AND AIM: Hepatitis B virus, hepatitis C virus, alcoholic consumption and non-alcoholic fatty liver are the major known risk factors for Hepatocellular carcinoma (HCC). There have been very few studies comparing the underlying biological mechanisms associated with the different etiologies of HCC. In this study, we hypothesized the existence of different regulatory networks associated with different liver disease etiologies involved in hepatocarcinogenesis. METHODS: Using upstream regulatory analysis tool in ingenuity pathway analysis software, URs were predicted using differential expressed genes for HCC to facilitate the interrogation of global gene regulation...
April 19, 2018: Journal of Gastroenterology and Hepatology
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