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Animal Genetics

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https://www.readbyqxmd.com/read/29034492/transcriptome-analyses-reveal-genes-and-pathways-associated-with-fatty-acid-composition-traits-in-pigs
#1
J Zhang, L Cui, J Ma, C Chen, B Yang, L Huang
Fatty acid composition is associated with meat quality in pigs as well as with obesity- and diabetes-related traits in humans. Liver and muscle are important tissues for fatty acid metabolism. In this study, we evaluated correlations between liver and muscle transcriptomes and fatty acid composition traits in muscle and abdominal fat tissues in 335 F2 pigs from a White Duroc × Erhualian F2 pig resource population. Transcripts significantly correlated with fatty acid composition traits were enriched for genes involved in the categories of triglyceride catabolic process, mitochondrial function, hematological and immune system, and disease such as Type II diabetes...
October 16, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29034488/exploiting-whole-genome-sequence-data-to-fine-map-and-characterize-candidate-genes-within-a-quantitative-trait-loci-region-affecting-androstenone-on-porcine-chromosome-5
#2
M van Son, R Agarwal, M P Kent, H Grove, E Grindflek, S Lien
Male piglets are routinely castrated to eliminate boar taint. However, this treatment is undesirable, and alternative approaches, including genetic strategies to reduce boar taint, are demanded. Androstenone is one of the causative agents of boar taint, and a QTL region affecting this pheromone has previously been reported on SSC5: 22.6-24.8 Mb in Duroc. The QTL region is one of the few reported for androstenone that does not simultaneously affect levels of other sex steroids. The main objective of this study was to fine map this QTL...
October 16, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023847/buffalo-srebp1-molecular-cloning-expression-and-association-analysis-with-milk-production-traits
#3
Tingxian Deng, Chunying Pang, Xiaoya Ma, Anqin Duan, Shasha Liang, Xingrong Lu, Xianwei Liang
No abstract text is available yet for this article.
October 12, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29024003/molecular-characterization-of-the-llama-fgf5-gene-and-identification-of-putative-loss-of-function-mutations
#4
M S Daverio, L Vidal-Rioja, E N Frank, F Di Rocco
Llama, the most numerous domestic camelid in Argentina, has good fiber-production ability. Although a few genes related to other productive traits have been characterized, the molecular genetic basis of fiber growth control in camelids is still poorly understood. Fibroblast growth factor 5 (FGF5) is a secreted signaling protein that controls hair growth in humans and other mammals. Mutations in the FGF5 gene have been associated with long-hair phenotypes in several species. Here, we sequenced the llama FGF5 gene, which consists of three exons encoding 813 bp...
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023911/genomic-diversity-and-population-structure-of-mexican-and-spanish-bovine-lidia-breed
#5
P G Eusebi, O Cortés, S Dunner, J Cañón
The Lidia bovine breed is distinguished for its low genetic exchangeability given its selection on aggressive behavior, its management uniqueness and its subdivided structure. In this study, we present a comprehensive genome-wide analysis of genetic diversity, population structure and admixture of 468 animals from Mexican and Spanish Lidia breed populations and 64 samples belonging to 10 Spanish native and American-creole breeds using 37 148 single nucleotide polymorphisms. We found similar average inbreeding values in the Lidia breed, with different distributions within groups; variability of inbreeding values among Spanish lineages was significant and no differences were found among the Mexican sub-populations...
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023809/a-nucleotide-substitution-in-exon-8-of-the-glucosylceramidase-beta-gene-is-associated-with-gaucher-disease-in-sheep
#6
Huitong Zhou, Yunsheng Zhang, Robert Suter, Hua Gong, Qian Fang, Ping Zhou, Jon G H Hickford
No abstract text is available yet for this article.
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023802/a-novel-12-bp-indel-polymorphism-within-the-gdf9-gene-is-significantly-associated-with-litter-size-and-growth-traits-in-goats
#7
Xinyu Wang, Qing Yang, Ke Wang, Sihuan Zhang, Chuanying Pan, Hong Chen, Lei Qu, Hailong Yan, Xianyong Lan
No abstract text is available yet for this article.
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023800/to-pace-or-not-to-pace-a-pilot-study-of-four-and-five-gaited-icelandic-horses-homozygous-for-the-dmrt3-gait-keeper-mutation
#8
K Jäderkvist Fegraeus, I Hirschberg, T Árnason, L Andersson, B D Velie, L S Andersson, G Lindgren
The Icelandic horse is a breed known mainly for its ability to perform the ambling four-beat gait 'tölt' and the lateral two-beat gait pace. The natural ability of the breed to perform these alternative gaits is highly desired by breeders. Therefore, the discovery that a nonsense mutation (C>A) in the DMRT3 gene was the main genetic factor for horses' ability to perform gaits in addition to walk, trot and canter was of great interest. Although several studies have demonstrated that homozygosity for the DMRT3 mutation is important for the ability to pace, only about 70% of the homozygous mutant (AA) Icelandic horses are reported to pace...
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28983931/two-brown-coat-colour-associated-tyrp1-variants-b-c-and-b-d-occur-in-leonberger-dogs
#9
Anna Letko, Cord Drögemüller
No abstract text is available yet for this article.
October 5, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28983925/a-genome-wide-significant-association-on-chromosome-2-for-footrot-resistance-susceptibility-in-swiss-white-alpine-sheep
#10
A Niggeler, J Tetens, A Stäuble, A Steiner, C Drögemüller
Footrot is one of the most important causes of lameness in global sheep populations and is characterized by a bacterial infection of the interdigital skin. As a multifactorial disease, its clinical representation depends not only on pathogen factors and environmental components but also on the individual resistance/susceptibility of the host. A genetic component has been shown in previous studies; however, so far no causative genetic variant influencing the risk of developing footrot has been identified. In this study, we genotyped 373 Swiss White Alpine sheep, using the ovine high-density 600k SNP chip, in order to run a DNA-based comparison of individuals with known clinical footrot status...
October 5, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28929497/genetic-diversity-and-paternal-origin-of-domestic-donkeys
#11
H Han, N Chen, J Jordana, C Li, T Sun, X Xia, X Zhao, C Ji, S Shen, J Yu, F Ainhoa, H Chen, C Lei, R Dang
Numerous studies have been conducted to investigate genetic diversity, origins and domestication of donkey using autosomal microsatellites and the mitochondrial genome, whereas the male-specific region of the Y chromosome of modern donkeys is largely uncharacterized. In the current study, 14 published equine Y chromosome-specific microsatellites (Y-STR) were investigated in 395 male donkey samples from China, Egypt, Spain and Peru using fluorescent labeled microsatellite markers. The results showed that seven Y-STRs-EcaYP9, EcaYM2, EcaYE2, EcaYE3, EcaYNO1, EcaYNO2 and EcaYNO4-were male specific and polymorphic, showing two to eight alleles in the donkeys studied...
September 19, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28901559/single-nucleotide-polymorphisms-for-dna-typing-in-the-domestic-horse
#12
H M Holl, J Vanhnasy, R E Everts, K Hoefs-Martin, D Cook, S A Brooks, M L Carpenter, C D Bustamante, C Lafayette
Genetic markers are important resources for individual identification and parentage assessment. Although short tandem repeats (STRs) have been the traditional DNA marker, technological advances have led to single nucleotide polymorphisms (SNPs) becoming an attractive alternative. SNPs can be highly multiplexed and automatically scored, which allows for easier standardization and sharing among laboratories. Equine parentage is currently assessed using STRs. We obtained a publicly available SNP dataset of 729 horses representing 32 diverse breeds...
September 13, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28872253/genome-wide-scans-between-two-honeybee-populations-reveal-putative-signatures-of-human-mediated-selection
#13
M Parejo, D Wragg, D Henriques, A Vignal, M Neuditschko
Human-mediated selection has left signatures in the genomes of many domesticated animals, including the European dark honeybee, Apis mellifera mellifera, which has been selected by apiculturists for centuries. Using whole-genome sequence information, we investigated selection signatures in spatially separated honeybee subpopulations (Switzerland, n = 39 and France, n = 17). Three different test statistics were calculated in windows of 2 kb (fixation index, cross-population extended haplotype homozygosity and cross-population composite likelihood ratio) and combined into a recently developed composite selection score...
September 4, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28872195/goat-domestication-and-breeding-a-jigsaw-of-historical-biological-and-molecular-data-with-missing-pieces
#14
REVIEW
M Amills, J Capote, G Tosser-Klopp
Domestic goats (Capra hircus) are spread across the five continents with a census of 1 billion individuals. The worldwide population of goats descends from a limited number of bezoars (Capra aegagrus) domesticated 10 000 YBP (years before the present) in the Fertile Crescent. The extraordinary adaptability and hardiness of goats favoured their rapid spread over the Old World, reaching the Iberian Peninsula and Southern Africa 7000 YBP and 2000 YBP respectively. Molecular studies have revealed one major mitochondrial haplogroup A and five less frequent haplogroups B, C, D, F and G...
September 4, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28872194/association-of-polymorphisms-in-the-5-regulatory-region-of-lepr-gene-with-meat-quality-traits-in-berkshire-pigs
#15
Jun-Mo Kim, Jong-Eun Park, Si-Woo Lee, Eun-Seok Cho, Bong-Hwan Choi, Hwa-Chun Park, Kyung-Tai Lee, Tae-Hun Kim
No abstract text is available yet for this article.
September 4, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28868799/low-mitochondrial-diversity-in-native-italian-pig-breeds-is-consistent-with-the-occurrence-of-strong-population-bottlenecks
#16
Joanna Kubejko, Marcel Amills, Fabio Pilla, Mariasilvia D'Andrea, Alex Clop
No abstract text is available yet for this article.
September 4, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28857209/a-genome-wide-association-study-suggests-new-candidate-genes-for-milk-production-traits-in-chinese-holstein-cattle
#17
S J Yue, Y Q Zhao, X R Gu, B Yin, Y L Jiang, Z H Wang, K R Shi
A genome-wide association study (GWAS) was conducted on 15 milk production traits in Chinese Holstein. The experimental population consisted of 445 cattle, each genotyped by the GGP (GeneSeek genomic profiling)-BovineLD V3 SNP chip, which had 26 151 public SNPs in its manifest file. After data cleaning, 20 326 SNPs were retained for the GWAS. The phenotypes were estimated breeding values of traits, provided by a public dairy herd improvement program center that had been collected once a month for 3 years...
August 30, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28856769/dermatosparaxis-in-white-dorper-sheep-confirmation-of-a-causative-nonsense-mutation-in-adamts2
#18
Sara Joller, Inês Berenguer Veiga, Cord Drögemüller
No abstract text is available yet for this article.
August 30, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28856698/splicing-site-disruption-in-the-kit-gene-as-strong-candidate-for-white-dominant-phenotype-in-an-italian-trotter
#19
Stefano Capomaccio, Marco Milanesi, Cristina Nocelli, Andrea Giontella, Andrea Verini-Supplizi, Michele Branca, Maurizio Silvestrelli, Katia Cappelli
No abstract text is available yet for this article.
August 30, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28856693/mitochondrial-dna-variation-in-ukrainian-wild-boars
#20
Joanna Kubejko, Alex Clop, Viktor Balatsky, Konstantin Pochernyaev, Shahin Eghbalsaied, Marcel Amills
No abstract text is available yet for this article.
August 30, 2017: Animal Genetics
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