Read by QxMD icon Read

Animal Genetics

Salvatore Mastrangelo, Andrea Criscione, Gianluca Sottile, Baldassare Portolano, Donata Marletta, Salvatore Bordonaro
No abstract text is available yet for this article.
January 15, 2019: Animal Genetics
Yuri Tani Utsunomiya, Rafaela Beatriz Pintor Torrecilha, Marco Milanesi, Silvana de Cássia Paulan, Adam Taiti Harth Utsunomiya, José Fernando Garcia
No abstract text is available yet for this article.
January 15, 2019: Animal Genetics
J Henkel, C Lafayette, S A Brooks, K Martin, L Patterson-Rosa, D Cook, V Jagannathan, T Leeb
White spotting phenotypes in horses are highly valued in some breeds. They are quite variable and may range from the common white markings up to completely white horses. EDNRB, KIT, MITF, PAX3 and TRPM1 represent known candidate genes for white spotting phenotypes in horses. For the present study, we investigated an American Paint Horse family segregating a phenotype involving white spotting and blue eyes. Six of eight horses with the white-spotting phenotype were deaf. We obtained whole-genome sequence data from an affected horse and specifically searched for structural variants in the known candidate genes...
January 15, 2019: Animal Genetics
D A S Duarte, C J Newbold, E Detmann, F F Silva, P H F Freitas, R Veroneze, M S Duarte
Genome-wide association studies (GWASes) have been performed to search for genomic regions associated with residual feed intake (RFI); however inconsistent results have been obtained. A meta-analysis may improve these results by decreasing the false-positive rate. Additionally, pathway analysis is a powerful tool that complements GWASes, as it enables identification of gene sets involved in the same pathway that explain the studied phenotype. Because there are no reports on GWAS pathways-based meta-analyses for RFI in beef cattle, we used several GWAS results to search for significant pathways that may explain the genetic mechanism underlying this trait...
January 15, 2019: Animal Genetics
S Kanthaswamy, R F Oldt, M Montes, A Falak
Almost half of all US households own a dog (Canis familiaris). Though these household pets can attack humans and other animals, they are also frequently victims of cruelty, neglect and theft. In human-oriented investigations, the tendency of domestic dogs to leave behind physical traces (such as hair) can serve as valuable links between crime scenes and suspects/victims. This demonstrated utility of canine biological evidence has created demand for genotyping marker sets for canine forensic genetic testing...
December 28, 2018: Animal Genetics
C Oget, B Servin, I Palhière
After domestication 11 000 years ago in Asia Minor, the goat followed human migration to Europe and Asia. It was then introduced in Africa and is now raised all over the world. In this study, we exploited a dataset composed of 54 000 SNPs (Illumina goat DNA chip) to analyze the genetic diversity of 223 individuals belonging to eight French breeds (Alpine, Angora, Corse, Fossés, Poitevine, Provençale, Pyrénées and Saanen). Analyses carried out included individual-based approaches (principal component analysis and population structure) and population-based approaches (phylogenetic tree constructions)...
December 13, 2018: Animal Genetics
Estelle R Bastounes, Halie M Rando, Jennifer L Johnson, Lyudmila N Trut, Benjamin N Sacks, Carlos A Driscoll, Bridgett vonHoldt, Anna V Kukekova
No abstract text is available yet for this article.
December 10, 2018: Animal Genetics
V Jagannathan, V Gerber, S Rieder, J Tetens, G Thaller, C Drögemüller, T Leeb
Whole-genome sequencing studies are vital to gain a thorough understanding of genomic variation. Here, we summarize the results of a whole-genome sequencing study comprising 88 horses and ponies from diverse breeds at 19.1× average coverage. The paired-end reads were mapped to the current EquCab3.0 horse reference genome assembly, and we identified approximately 23.5 million single nucleotide variants and 2.3 million short indel variants. Our dataset included at least 7 million variants that were not previously reported...
December 7, 2018: Animal Genetics
Laura Barrientos, Arianna Maiolini, Annakatrin Häni, Vidhya Jagannathan, Tosso Leeb
No abstract text is available yet for this article.
December 7, 2018: Animal Genetics
S Hofstetter, F Seefried, I M Häfliger, V Jagannathan, T Leeb, C Drögemüller
Recently, the Swiss breeding association reported an increasing number of white-spotted cattle in the Brown Swiss breed, which is normally solid brown coloured. A total of 60 Brown Swiss cattle with variably sized white abdominal spots, facial markings and depigmented claws were collected for this study. A genome-wide association study using 40k SNP genotypes of 20 cases and 1619 controls enabled us to identify an associated genome region on chromosome 22 containing the MITF gene, encoding the melanogenesis associated transcription factor...
December 2, 2018: Animal Genetics
W Park, K Srikanth, D Lim, M Park, T Hur, S Kemp, T Dessie, M S Kim, S-R Lee, M F W Te Pas, J-M Kim, J-E Park
Ethiopia is an ecologically diverse country; the low altitude regions are hot and humid whereas the high altitude regions are cooler. In this study we analyzed the transcriptome response of high altitude (Addis Ababa) and low altitude (Awash) chickens to heat stress conditions that are prevalent in the low altitude regions. The chickens were free ranged for 20 h in an enclosure in Awash, and then the heart, breast muscle and spleen tissues were collected at 6:00 am, 12:00 noon and 6:00 pm to follow a daily circadian cycle...
November 25, 2018: Animal Genetics
N Sevane, R Martínez, M W Bruford
Enhancing climate resilience and sustainable production for animals in harsh environments are important goals for the livestock industry given the predicted impacts of climate change. Rapid adaptation to extreme climatic conditions has already been imposed on livestock species, including those exported after Columbus's arrival in the Americas. We compared the methylomes of two Creole cattle breeds living in tropical environments with their putative Spanish ancestors to understand the epigenetic mechanisms underlying rapid adaptation of a domestic species to a new and more physiologically challenging environment...
November 22, 2018: Animal Genetics
E Salmela, J Niskanen, M Arumilli, J Donner, H Lohi, M K Hytönen
Curly fur is a common phenotype in many dog breeds, known to result from a missense variant (c.451C>T) in exon 2 of the keratin 71 (KRT71) gene. During screening for this variant across various breeds, we found that Curly Coated Retrievers (CCRs) fixed with the trait did not carry the known variant. By analysis of whole-genome sequencing data of one CCR we identified a novel genetic cause for curly fur. We found a novel structural variant in exon 7 of the KRT71 gene (c.1266_1273delinsACA) that was predicted to result in a frameshift and stop loss, therefore significantly affecting the structure of the protein, if translated...
November 19, 2018: Animal Genetics
A Bauer, S Hadji Rasouliha, M T Brunner, V Jagannathan, I Bucher, J Bannoehr, K Varjonen, R Bond, K Bergvall, M M Welle, P Roosje, T Leeb
Major characteristics of coat variation in dogs can be explained by variants in only a few genes. Until now, only one missense variant in the KRT71 gene, p.Arg151Trp, has been reported to cause curly hair in dogs. However, this variant does not explain the curly coat in all breeds as the mutant 151 Trp allele, for example, is absent in Curly Coated Retrievers. We sequenced the genome of a Curly Coated Retriever at 22× coverage and searched for variants in the KRT71 gene. Only one protein-changing variant was present in a homozygous state in the Curly Coated Retriever and absent or present in a heterozygous state in 221 control dogs from different dog breeds...
November 15, 2018: Animal Genetics
R Liu, M Zheng, J Wang, H Cui, Q Li, J Liu, G Zhao, J Wen
Improvements in living standards have resulted in consumers having higher expectations for chicken meat quality. This is particularly true in Asia, where there is high consumer preference for local breeds. Nothing is presently known about the effectiveness of using genomic selection (GS) strategies in chickens to genetically improve meat quality traits that cannot be measured in living potential parents. In this study, 724 Beijing-You chickens were used as a training population; all were genotyped using Illumina 60K SNP chips, and intramuscular fat content in breast muscle (IMFbr ) was measured...
November 15, 2018: Animal Genetics
R D Houston, D J Macqueen
Atlantic salmon (Salmo salar L.) is among the most iconic and economically important fish species and was the first member of Salmonidae to have a high-quality reference genome assembly published. Advances in genomics have become increasingly central to the genetic improvement of farmed Atlantic salmon as well as conservation of wild salmon stocks. The salmon genome has also been pivotal in shaping our understanding of the evolutionary and functional consequences arising from an ancestral whole-genome duplication event characterising all Salmonidae members...
November 14, 2018: Animal Genetics
H Zhao, A Fuller, W Thongda, H Mohammed, J Abernathy, B Beck, E Peatman
White bass (Morone chrysops), striped bass and their interspecific hybrid are important game fishes, whereas the hybrid striped bass is an important aquaculture species in the US. Numerous state, federal and private hatcheries, therefore, rear these species for stocking purposes as well as for food fish. Although striped bass populations (both wild and domesticated) have been extensively evaluated, relatively little effort has been directed toward the study and improvement of white bass. In this study, we developed SNP resources to examine the genetic relationships among a long-term domesticated white bass line and five potential founder stocks for selective breeding collected from drainages in Arkansas, Texas and Alabama...
November 14, 2018: Animal Genetics
X Xia, K Qu, G Zhang, Y Jia, Z Ma, X Zhao, Y Huang, H Chen, B Huang, C Lei
Complete mitochondrial DNA D-loop sequences of 1105 individuals were used to assess the diversity of maternal lineages of cattle populations in China. In total, 250 taurine and 88 zebu haplotypes were identified. Five main haplogroups-T1a, T2, T3, T4 and T5-were identified in Bos taurus, whereas Bos indicus harbored two haplogroups-I1 and I2. Our results suggest that the distribution of T1a in Asia was concentrated mainly in the northeast region (northeast China, Korea and Japan); haplogroups T2, T3 and T4 were predominant in Chinese cattle; and T5 was sporadically detected in Mongolian and Pingwu cattle...
November 13, 2018: Animal Genetics
Samantha K Beeson, Robert J Schaefer, Victor C Mason, Molly E McCue
No abstract text is available yet for this article.
November 13, 2018: Animal Genetics
X Xia, Y Yao, C Li, F Zhang, K Qu, H Chen, B Huang, C Lei
With its vast territory and complex natural environment, China boasts rich cattle genetic resources. To gain the further insight into the genetic diversity and paternal origins of Chinese cattle, we analyzed the polymorphism of Y-SNPs (UTY19 and ZFY10) and Y-STRs (INRA189 and BM861) in 34 Chinese cattle breeds/populations, including 606 males representative of 24 cattle breeds/populations collected in this study as well as previously published data for 302 bulls. Combined genotypic data identified 14 Y-chromosome haplotypes that represented three haplogroups...
November 13, 2018: Animal Genetics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"