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Animal Genetics

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https://www.readbyqxmd.com/read/29230835/genetic-contributions-to-precocity-traits-in-racing-thoroughbreds
#1
G Farries, P A McGettigan, K F Gough, B A McGivney, D E MacHugh, L M Katz, E W Hill
Adaptation to early training and racing (i.e. precocity), which is highly variable in racing Thoroughbreds, has implications for the selection and training of horses. We hypothesised that precocity in Thoroughbred racehorses is heritable. Age at first sprint training session (work day), age at first race and age at best race were used as phenotypes to quantify precocity. Using high-density SNP array data, additive SNP heritability (hSNP2) was estimated to be 0.17, 0.14 and 0.17 for the three traits respectively...
December 12, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29194688/the-genetic-diversity-and-population-structures-of-indigenous-pig-breeds-in-zhejiang-province-revealed-by-ggrs-sequencing
#2
J Chen, J Peng, Q Xiao, Y Pan, X Zhang, L J Lo, N Xu
Chinese indigenous pigs in Zhejiang Province are well known for their high fecundity. In order to verify breed subdivision at the genomic level, we investigated genetic diversity and population structure of seven breeds and made comparisons with three Western pig breeds using next-generation sequencing data. Parameters obtained from allelic richness and proportion of polymorphic markers indicated that the genetic diversity of the Chinese indigenous pigs was higher than that of the Western pigs, with the highest and lowest values found in the Chaluand and the Landrace pigs respectively...
December 1, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29194674/a-whole-genome-sequence-association-study-for-puberty-in-a-large-duroc%C3%A2-%C3%A3-%C3%A2-erhualian-f2-population
#3
W S Xin, F Zhang, G R Yan, W W Xu, S J Xiao, Z Y Zhang, L S Huang
A large proportion of gilts and sows are culled from reproduction populations because of anestrus and pubertal reproductive failure. Selecting early onset of puberty gilts has a favorable effect on sows' reproductivity. However, age at puberty is hard to be routinely measured in commercial herds. With molecular genetic predictors, identifying individuals that have a propensity for early onset of puberty can be simplified. We previously performed genome scanning and a genome-wide association study for puberty in an F2 resource population using 183 microsatellites and 62 125 SNPs respectively...
December 1, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29168191/genetic-variants-in-il15-promoter-affect-transcription-activity-and-intramuscular-fat-deposition-in-longissimus-dorsi-muscle-of-pigs
#4
D He, Z Jiang, Y Tian, H Han, M Xia, W Wei, L Zhang, J Chen
Intramuscular fat (IMF) content is a key aspect of pork quality. Elucidation of intramuscular adipocyte regulation mechanisms is important for improving IMF content. Intramuscular adipocytes are dispersed among muscle fibers, so they are inclined to be affected by muscle-derived factors. Interleukin-15 is a major muscle-secreted factor. In this study, the genetic and physiological impacts of IL15 on adipogenesis is investigated. The promoter region of IL15 was scanned by comparative sequencing using two DNA pools of high- and low-IMF individuals...
November 22, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29076225/association-of-genetic-variants-and-expression-levels-of-porcine-fabp4-and-fabp5-genes
#5
M Ballester, A Puig-Oliveras, A Castelló, M Revilla, A I Fernández, J M Folch
The FABP4 and FABP5 genes, coding for fatty acid transport proteins, have long been studied as positional candidate genes for SSC4 QTL affecting fat deposition and composition traits in pigs. Polymorphisms in these genes, FABP4:g.2634_2635insC and FABP5:g.3000T>G, have previously been associated with fatness traits in an Iberian by Landrace cross (IBMAP). The aim of the present work was to evaluate the functional implication of these genetic variants. For this purpose, FABP4 and FABP5 mRNA expression levels in 114 BC1_LD animals (25% Iberian × 75% Landrace) were analyzed using real-time quantitative PCR in backfat and muscle...
October 27, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29076177/genome-wide-association-analysis-of-residual-feed-intake-in-junmu-no-1-white-pigs
#6
C Bai, Y Pan, D Wang, F Cai, S Yan, Z Zhao, B Sun
Residual feed intake (RFI) is a measure of feed efficiency. Pigs with low RFI have reduced feed costs without compromising their growth. For marker-assisted selection, it is helpful to identify genes or genetic markers associated with RFI in animals with improved feed efficiency at an early age. Using Illumina's PorcineSNP60 BeadChip, we performed a pilot genome-wide association study of 217 Junmu No. 1 white male pigs phenotyped for RFI. Two-step and one-step methods were used separately to identify associated SNPs...
October 27, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29076162/rate-of-bovine-heteropaternal-superfecundation-in-the-irish-national-herd-twins-with-different-sires
#7
Matthew C McClure, Jennifer C McClure, John McCarthy
No abstract text is available yet for this article.
October 27, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29044715/bayesian-genome-wide-association-analysis-for-body-weight-in-farmed-atlantic-salmon-salmo-salar-l
#8
G M Yoshida, J P Lhorente, R Carvalheiro, J M Yáñez
We performed a genome-wide association study to detect markers associated with growth traits in Atlantic salmon. The analyzed traits included body weight at tagging (BWT) and body weight at 25 months (BW25M). Genotypes of 4662 animals were imputed from the 50K SNP chip to the 200K SNP chip using fimpute software. The markers were simultaneously modeled using Bayes C to identify genomic regions associated with the traits. We identified windows explaining a maximum of 3.71% and 3.61% of the genetic variance for BWT and BW25M respectively...
October 17, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29034492/transcriptome-analyses-reveal-genes-and-pathways-associated-with-fatty-acid-composition-traits-in-pigs
#9
J Zhang, L Cui, J Ma, C Chen, B Yang, L Huang
Fatty acid composition is associated with meat quality in pigs as well as with obesity- and diabetes-related traits in humans. Liver and muscle are important tissues for fatty acid metabolism. In this study, we evaluated correlations between liver and muscle transcriptomes and fatty acid composition traits in muscle and abdominal fat tissues in 335 F2 pigs from a White Duroc × Erhualian F2 pig resource population. Transcripts significantly correlated with fatty acid composition traits were enriched for genes involved in the categories of triglyceride catabolic process, mitochondrial function, hematological and immune system, and disease such as Type II diabetes...
October 16, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29034488/exploiting-whole-genome-sequence-data-to-fine-map-and-characterize-candidate-genes-within-a-quantitative-trait-loci-region-affecting-androstenone-on-porcine-chromosome-5
#10
M van Son, R Agarwal, M P Kent, H Grove, E Grindflek, S Lien
Male piglets are routinely castrated to eliminate boar taint. However, this treatment is undesirable, and alternative approaches, including genetic strategies to reduce boar taint, are demanded. Androstenone is one of the causative agents of boar taint, and a QTL region affecting this pheromone has previously been reported on SSC5: 22.6-24.8 Mb in Duroc. The QTL region is one of the few reported for androstenone that does not simultaneously affect levels of other sex steroids. The main objective of this study was to fine map this QTL...
October 16, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023847/buffalo-srebp1-molecular-cloning-expression-and-association-analysis-with-milk-production-traits
#11
Tingxian Deng, Chunying Pang, Xiaoya Ma, Anqin Duan, Shasha Liang, Xingrong Lu, Xianwei Liang
No abstract text is available yet for this article.
October 12, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29024003/molecular-characterization-of-the-llama-fgf5-gene-and-identification-of-putative-loss-of-function-mutations
#12
M S Daverio, L Vidal-Rioja, E N Frank, F Di Rocco
Llama, the most numerous domestic camelid in Argentina, has good fiber-production ability. Although a few genes related to other productive traits have been characterized, the molecular genetic basis of fiber growth control in camelids is still poorly understood. Fibroblast growth factor 5 (FGF5) is a secreted signaling protein that controls hair growth in humans and other mammals. Mutations in the FGF5 gene have been associated with long-hair phenotypes in several species. Here, we sequenced the llama FGF5 gene, which consists of three exons encoding 813 bp...
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023911/genomic-diversity-and-population-structure-of-mexican-and-spanish-bovine-lidia-breed
#13
P G Eusebi, O Cortés, S Dunner, J Cañón
The Lidia bovine breed is distinguished for its low genetic exchangeability given its selection on aggressive behavior, its management uniqueness and its subdivided structure. In this study, we present a comprehensive genome-wide analysis of genetic diversity, population structure and admixture of 468 animals from Mexican and Spanish Lidia breed populations and 64 samples belonging to 10 Spanish native and American-creole breeds using 37 148 single nucleotide polymorphisms. We found similar average inbreeding values in the Lidia breed, with different distributions within groups; variability of inbreeding values among Spanish lineages was significant and no differences were found among the Mexican sub-populations...
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023809/a-nucleotide-substitution-in-exon-8-of-the-glucosylceramidase-beta-gene-is-associated-with-gaucher-disease-in-sheep
#14
Huitong Zhou, Yunsheng Zhang, Robert Suter, Hua Gong, Qian Fang, Ping Zhou, Jon G H Hickford
No abstract text is available yet for this article.
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023802/a-novel-12-bp-indel-polymorphism-within-the-gdf9-gene-is-significantly-associated-with-litter-size-and-growth-traits-in-goats
#15
Xinyu Wang, Qing Yang, Ke Wang, Sihuan Zhang, Chuanying Pan, Hong Chen, Lei Qu, Hailong Yan, Xianyong Lan
No abstract text is available yet for this article.
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/29023800/to-pace-or-not-to-pace-a-pilot-study-of-four-and-five-gaited-icelandic-horses-homozygous-for-the-dmrt3-gait-keeper-mutation
#16
K Jäderkvist Fegraeus, I Hirschberg, T Árnason, L Andersson, B D Velie, L S Andersson, G Lindgren
The Icelandic horse is a breed known mainly for its ability to perform the ambling four-beat gait 'tölt' and the lateral two-beat gait pace. The natural ability of the breed to perform these alternative gaits is highly desired by breeders. Therefore, the discovery that a nonsense mutation (C>A) in the DMRT3 gene was the main genetic factor for horses' ability to perform gaits in addition to walk, trot and canter was of great interest. Although several studies have demonstrated that homozygosity for the DMRT3 mutation is important for the ability to pace, only about 70% of the homozygous mutant (AA) Icelandic horses are reported to pace...
October 11, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28983931/two-brown-coat-colour-associated-tyrp1-variants-b-c-and-b-d-occur-in-leonberger-dogs
#17
Anna Letko, Cord Drögemüller
No abstract text is available yet for this article.
October 5, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28983925/a-genome-wide-significant-association-on-chromosome-2-for-footrot-resistance-susceptibility-in-swiss-white-alpine-sheep
#18
A Niggeler, J Tetens, A Stäuble, A Steiner, C Drögemüller
Footrot is one of the most important causes of lameness in global sheep populations and is characterized by a bacterial infection of the interdigital skin. As a multifactorial disease, its clinical representation depends not only on pathogen factors and environmental components but also on the individual resistance/susceptibility of the host. A genetic component has been shown in previous studies; however, so far no causative genetic variant influencing the risk of developing footrot has been identified. In this study, we genotyped 373 Swiss White Alpine sheep, using the ovine high-density 600k SNP chip, in order to run a DNA-based comparison of individuals with known clinical footrot status...
October 5, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28929497/genetic-diversity-and-paternal-origin-of-domestic-donkeys
#19
H Han, N Chen, J Jordana, C Li, T Sun, X Xia, X Zhao, C Ji, S Shen, J Yu, F Ainhoa, H Chen, C Lei, R Dang
Numerous studies have been conducted to investigate genetic diversity, origins and domestication of donkey using autosomal microsatellites and the mitochondrial genome, whereas the male-specific region of the Y chromosome of modern donkeys is largely uncharacterized. In the current study, 14 published equine Y chromosome-specific microsatellites (Y-STR) were investigated in 395 male donkey samples from China, Egypt, Spain and Peru using fluorescent labeled microsatellite markers. The results showed that seven Y-STRs-EcaYP9, EcaYM2, EcaYE2, EcaYE3, EcaYNO1, EcaYNO2 and EcaYNO4-were male specific and polymorphic, showing two to eight alleles in the donkeys studied...
September 19, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28905510/corrigendum
#20
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Animal Genetics
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