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Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]

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https://www.readbyqxmd.com/read/28631018/personalized-radiotherapy-for-invasive-breast-cancer-in-2017-national-s3-guidelines-and-degro-and-ago-recommendations
#1
EDITORIAL
Frederik Wenz, Wilfried Budach
No abstract text is available yet for this article.
June 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28631017/proton-therapy-of-iris-melanoma-with-50%C3%A2-cge-influence-of-target-volume-on-clinical-outcome
#2
Aline I Riechardt, Bettina Karle, Dino Cordini, Jens Heufelder, Volker Budach, Antonia M Joussen, Johannes Gollrad
PURPOSE: The aim of this study was to evaluate local tumour control, incidence of radiation-induced glaucoma and associated interventions of sector-based and whole anterior segment proton beam therapy (PBT) for the treatment of iris melanoma. PATIENTS AND METHODS: We retrospectively analysed the data of 77 patients with iris melanoma who underwent PBT applied as 50 CGE in four daily fractions. Of the patients, 47 received PBT with a circular-shaped collimator and 30 with a conformal sector-shaped target volume...
June 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28623436/high-dose-rate-brachytherapy-as-salvage-modality-for-locally-recurrent-prostate-cancer-after-definitive-radiotherapy-a%C3%A2-systematic-review
#3
REVIEW
Georgios Chatzikonstantinou, Nikolaos Zamboglou, Claus Rödel, Eleni Zoga, Iosif Strouthos, Saeed Ahmed Butt, Nikolaos Tselis
PURPOSE: To review the current status of interstitial high-dose-rate brachytherapy as a salvage modality (sHDR BRT) for locally recurrent prostate cancer after definitive radiotherapy (RT). MATERIALS AND METHODS: A literature search was performed in PubMed using "high-dose-rate, brachytherapy, prostate cancer, salvage" as search terms. In all, 51 search results published between 2000 and 2016 were identified. Data tables were generated and summary descriptions created...
June 16, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28620751/impact-of-a-rectal-and-bladder-preparation-protocol-on-prostate-cancer-outcome-in-patients-treated-with-external-beam-radiotherapy
#4
A Maggio, D Gabriele, E Garibaldi, S Bresciani, E Delmastro, A Di Dia, A Miranti, M Poli, T Varetto, M Stasi, P Gabriele
PURPOSE AND OBJECTIVE: To test the hypothesis that a rectal and bladder preparation protocol is associated with an increase in prostate cancer specific survival (PCSS), clinical disease free survival (CDFS) and biochemical disease free survival (BDFS). PATIENTS AND METHODS: From 1999 to 2012, 1080 prostate cancer (PCa) patients were treated with three-dimensional conformal radiotherapy (3DCRT). Of these patients, 761 were treated with an empty rectum and comfortably full bladder (RBP) preparation protocol, while for 319 patients no rectal/bladder preparation (NRBP) protocol was adopted...
June 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28620750/high-precision-radiotherapy-for-meningiomas-long-term-results-and-patient-reported-outcome-pro
#5
Kerstin A Kessel, Hanna Fischer, Markus Oechnser, Claus Zimmer, Bernhard Meyer, Stephanie E Combs
OBJECTIVE: To evaluate long-term outcome after high-precision radiotherapy (RT) of meningioma patients in terms of survival and side effects. METHODS: We analyzed 275 meningioma cases: 147 low-grade and 43 high-grade meningiomas (WHO II: n = 40, III: n = 3). In all, 85 patients had no pathologically confirmed histology but were determined as low-grade based on multimodal imaging. Surgery was performed in 183 cases. RT was delivered as either radiosurgery (RS, n = 16), fractionated stereotactic radiotherapy (FSRT, n = 241), or intensity-modulated radiation therapy (IMRT, n = 18)...
June 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28616822/a%C3%A2-comparison-of-swallowing-dysfunction-after-three-dimensional-conformal-and-intensity-modulated-radiotherapy-a%C3%A2-systematic-review-by-the-italian-head-and-neck-radiotherapy-study-group
#6
REVIEW
Stefano Ursino, Elisa D'Angelo, Rosario Mazzola, Anna Merlotti, Riccardo Morganti, Agostino Cristaudo, Fabiola Paiar, Daniela Musio, Daniela Alterio, Almalina Bacigalupo, Elvio Grazioso Russi, Frank Lohr
PURPOSE: Dysphagia is one of the most important treatment-related side effects in head and neck cancer (HNC), as it can lead to severe life-threating complications such as aspiration pneumonia and malnutrition. Intensity-modulated radiotherapy (IMRT) could reduce swallowing dysfunction by producing a concave dose distribution and reducing doses to the swallowing-related organs at risk (SWOARs). The aim of this study was to review the current literature in order to compare swallowing outcomes between IMRT and three-dimensional conformal radiotherapy (3DCRT)...
June 14, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28616821/re-irradiation-after-gross-total-resection-of-recurrent-glioblastoma-spatial-pattern-of-recurrence-and-a-review-of-the-literature-as-a-basis-for-target-volume-definition
#7
Christoph Straube, Greeshma Elpula, Jens Gempt, Julia Gerhardt, Stefanie Bette, Claus Zimmer, Friederike Schmidt-Graf, Bernhard Meyer, Stephanie E Combs
BACKGROUND: Currently, patients with gross total resection (GTR) of recurrent glioblastoma (rGBM) undergo adjuvant chemotherapy or are followed up until progression. Re-irradiation, as one of the most effective treatments in macroscopic rGBM, is withheld in this situation, as uncertainties about the pattern of re-recurrence, the target volume, and also the efficacy of early re-irradiation after GTR exist. METHODS: Imaging and clinical data from 26 consecutive patients with GTR of rGBM were analyzed...
June 14, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28612083/does-combination-therapy-with-tamsulosin-and-trospium-chloride-improve-lower-urinary-tract-symptoms-after-seeds-brachytherapy-for-prostate-cancer-compared-with-tamsulosin-alone-a%C3%A2-prospective-randomized-controlled-trial
#8
Miao Yan, Peng Xue, Kunpeng Wang, Guojun Gao, Wei Zhang, Fanghu Sun
OBJECTIVE: To compare the efficacy of combination therapy with an alpha-blocker and an anticholinergic to monotherapy with an alpha blocker on lower urinary tract symptoms (LUTS) following brachytherapy in prostate cancer patients. MATERIAL AND METHODS: A total of 124 patients that had been clinically diagnosed with localized prostate cancer and underwent prostate brachytherapy were enrolled in the present study. Patients were randomized and allocated to two groups, including 60 to the combination group (tamsulosin 0...
June 13, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28608305/quality-assurance-of-the-preopanc-trial-2012-003181-40-for-preoperative-radiochemotherapy-in-pancreatic-cancer-the-dummy-run
#9
Eva Versteijne, Eelco Lens, Astrid van der Horst, Arjan Bel, Jorrit Visser, Cornelis J A Punt, Mustafa Suker, Casper H J van Eijck, Geertjan van Tienhoven
BACKGROUND: The Dutch Pancreatic Cancer Group initiated the national, multicentre, controlled PREOPANC trial, randomising between preoperative radiochemotherapy and direct explorative laparotomy for patients with (borderline) resectable pancreatic cancer. The aim of this dummy run is to evaluate compliance with the radiotherapy protocol of this trial, and the quality of delineation and radiation plans. METHODS: Eleven radiation oncology departments open for accrual of patients in the PREOPANC trial were provided with all necessary information of a selected 'dummy' patient...
June 12, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28573476/single-vs-multiple-fraction-regimens-for-palliative-radiotherapy-treatment-of-multiple-myeloma-a-prospective-randomised-study
#10
Milda Rudzianskiene, Arturas Inciura, Rolandas Gerbutavicius, Viktoras Rudzianskas, Andrius Macas, Renata Simoliuniene, Ruta Dambrauskiene, Greta Emilia Kiavialaitis, Elona Juozaityte
PURPOSE: To compare the impact of a single fraction (8 Gy × 1 fraction) and multifraction (3 Gy × 10 fractions) radiotherapy regimens on pain relief, recalcification and the quality of life (QoL) in patients with bone destructions due to multiple myeloma (MM). PATIENTS AND METHODS: In all, 101 patients were included in a randomised prospective clinical trial: 58 patients were included in the control arm (3 Gy × 10 fractions) and 43 patients into the experimental arm (8 Gy × 1 fraction)...
June 1, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28573475/patient-reported-symptoms-during-radiotherapy-clinically-relevant-symptom-burden-in-patients-treated-with-palliative-and-curative-intent
#11
Philipp Körner, Katja Ehrmann, Johann Hartmannsgruber, Michaela Metz, Sabrina Steigerwald, Michael Flentje, Birgitt van Oorschot
BACKGROUND: The benefits of patient-reported symptom assessment combined with integrated palliative care are well documented. This study assessed the symptom burden of palliative and curative-intent radiation oncology patients. PATIENTS AND METHODS: Prior to first consultation and at the end of RT, all adult cancer patients planned to receive fractionated percutaneous radiotherapy (RT) were asked to answer the Edmonton Symptom Assessment Scale (ESAS; nine symptoms from 0 = no symptoms to 10 = worst possible symptoms)...
June 1, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28567504/a%C3%A2-clinical-example-of-extreme-dose-exposure-for-an-implanted-cardioverter-defibrillator-beyond-the-degro-guidelines
#12
Yoana Hristova, Janett Köhn, Stefanie Preuß, Claus Rödel, Panagiotis Balermpas
INTRODUCTION: Considering that the number of malignant diseases in patients over 65 years of age is increasing, it often occurs that patients who carry a cardiac implanted electronic device must undergo radiotherapy. Ionizing radiation can disturb the function of the implantable cardioverter-defibrillator (ICD). As a result of this, an update of the DEGRO/DKG guidelines for radiotherapy of this patient group has been published. METHODS: We report the case of a patient with an ICD and T‑lymphoblastic lymphoma with cardiac involvement, who received i...
May 31, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28567503/planning-benchmark-study-for-sbrt-of-early-stage-nsclc-results-of-the-degro-working-group-stereotactic-radiotherapy
#13
Christos Moustakis, Oliver Blanck, Fatemeh Ebrahimi Tazehmahalleh, Mark Ka Heng Chan, Iris Ernst, Thomas Krieger, Marciana-Nona Duma, Markus Oechsner, Ute Ganswindt, Christian Heinz, Horst Alheit, Hilbert Blank, Ursula Nestle, Rolf Wiehle, Christine Kornhuber, Christian Ostheimer, Cordula Petersen, Gerhard Pollul, Wolfgang Baus, Georg Altenstein, Eric Beckers, Katrin Jurianz, Florian Sterzing, Matthias Kretschmer, Heinrich Seegenschmiedt, Torsten Maass, Stefan Droege, Ulrich Wolf, Juergen Schoeffler, Uwe Haverkamp, Hans Theodor Eich, Matthias Guckenberger
PURPOSE: The aim was to evaluate stereotactic body radiation therapy (SBRT) treatment planning variability for early stage nonsmall cell lung cancer (NSCLC) with respect to the published guidelines of the Stereotactic Radiotherapy Working Group of the German Society for Radiation Oncology (DEGRO). MATERIALS AND METHODS: Planning computed tomography (CT) scan and the structure sets (planning target volume, PTV; organs at risk, OARs) of 3 patients with early stage NSCLC were sent to 22 radiotherapy departments with SBRT experience: each department was asked to prepare a treatment plan according to the DEGRO guidelines...
May 31, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28540428/erratum-to-combined-p16-and-p53-expression-in-cervical-cancer-of-unknown-primary-and-other-prognostic-parameters
#14
Müjdat Yildirim, Jens Müller von der Grün, Ria Winkelmann, Emmanouil Fokas, Franz Rödel, Hanns Ackermann, Claus Rödel, Panagiotis Balermpas
No abstract text is available yet for this article.
May 24, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28526916/-salvage-radiotherapy-with-antiandrogen-therapy-after-prostatectomy-significant-overall-survival-benefit-compared-to-radiotherapy-alone
#15
Gregor Goldner
No abstract text is available yet for this article.
May 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28523338/-how-long-should-we-wait-upon-completion-of-chemoradiotherapy-before-assessment-of-tumor-response-in-anal-cancer
#16
Daniel Martin, Claus Rödel, Emmanouil Fokas
No abstract text is available yet for this article.
May 18, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28516198/-local-consolidative-therapy-improves-progression-free-survival-in-patients-with-oligometastatic-nsclc-results-of-a-randomized-phase%C3%A2-ii-study
#17
Tobias Finazzi, Matthias Guckenberger
No abstract text is available yet for this article.
May 17, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28500491/hyperfractionated-accelerated-radiation-therapy-plus-cetuximab-plus-cisplatin-chemotherapy-in-locally-advanced-inoperable-squamous-cell-carcinoma-of-the-head-and-neck-final-5%C3%A2-year-results-of-a-phase%C3%A2-ii-study
#18
Thomas Kuhnt, Andreas Schreiber, Anett Pirnasch, Matthias G Hautmann, Peter Hass, Frank P Sieker, Rita Engenhart-Cabillic, Michael Richter, Kathrin Dellas, Jürgen Dunst
BACKGROUND: Cetuximab (CET) is a potent inhibitor of the epidermal growth factor receptor and has been shown to have activity in squamous cell carcinoma of the head and neck (SCCHN). We conducted a single-arm phase II trial of a combination therapy comprising cisplatin (CIS), CET and hyperfractionated accelerated radiotherapy (HART). PATIENTS AND METHODS: Patients with UICC stage III or IVA/B, M0 SCCHN were enrolled and treated with an initial dose of CET (400 mg/m(2)) and then with a weekly dosage of 250 mg/m(2) during HART...
May 12, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28500490/effects-of-definitive-and-salvage-radiotherapy-on-the-distribution-of-lymphocyte-subpopulations-in-prostate-cancer-patients
#19
Eva K Sage, Thomas E Schmid, Hans Geinitz, Mathias Gehrmann, Michael Sedelmayr, Marciana N Duma, Stephanie E Combs, Gabriele Multhoff
BACKGROUND: Radiotherapy (RT) is an established treatment for patients with primary and recurrent prostate cancer. Herein, the effects of definitive and salvage RT on the composition of lymphocyte subpopulations were investigated in patients with prostate cancer to study potential immune effects. PATIENTS AND METHODS: A total of 33 prostate cancer patients were treated with definitive (n = 10) or salvage RT (n = 23) after biochemical relapse. The absolute number of lymphocytes and the distribution of lymphocyte subpopulations were analyzed by multiparameter flow cytometry before RT, at the end of RT, and in the follow-up period...
May 12, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28492995/general-health-status-of-long-term-cervical-cancer-survivors-after-radiotherapy
#20
Lee Sung Uk, Kim Young Ae, Yoon Young-Ho, Kim Yeon-Joo, Lim Myong Cheol, Park Sang-Yoon, Seo Sang-Soo, Park Ji Eun, Kim Joo-Young
PURPOSE: To evaluate the global health status of long-term cervical cancer survivors (LCCS) who survived for more than 4 years after curative radiation treatment (RT). PATIENTS AND METHODS: Medical records of 562 women treated with RT in our institution between 2003 and 2010 were reviewed. Excluding 259 women who died of disease or were lost to follow-up, disease status and late morbidities were evaluated in 303 LCCS. Quality of life (QoL) was analyzed in 168 LCCS using a questionnaire from the European Organization for the Research and Treatment of Cancer, and the results were compared with an age-matched healthy Korean female population...
May 10, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
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