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Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]

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https://www.readbyqxmd.com/read/30649567/icru-report-91-on-prescribing-recording-and-reporting-of-stereotactic-treatments-with-small-photon-beams-statement-from-the-degro-dgmp-working-group-stereotactic-radiotherapy-and-radiosurgery
#1
REVIEW
Lotte Wilke, Nicolaus Andratschke, Oliver Blanck, Thomas B Brunner, Stephanie E Combs, Anca-Ligia Grosu, Christos Moustakis, Daniela Schmitt, Wolfgang W Baus, Matthias Guckenberger
The International Commission on Radiation Units and Measurements (ICRU) report 91 with the title "prescribing, recording, and reporting of stereotactic treatments with small photon beams" was published in 2017. This extensive publication covers different relevant aspects of stereotactic radiotherapy such as small field dosimetry, accuracy requirements for volume definition and planning algorithms, and the precise application of treatment by means of image guidance. Finally, recommendations for prescribing, recording and reporting are given...
January 16, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30610356/predicting-tumor-responses-and-patient-survival-in-chemoradiotherapy-treated-patients-with-non-small-cell-lung-cancer-using-dynamic-contrast-enhanced-integrated-magnetic-resonance-positron-emission-tomography
#2
Yu-Sen Huang, Jenny Ling-Yu Chen, Jo-Yu Chen, Yee-Fan Lee, Jei-Yie Huang, Sung-Hsin Kuo, Ruoh-Fang Yen, Yeun-Chung Chang
PURPOSE: We investigated whether radiologic parameters by dynamic contrast-enhanced (DCE) integrated magnetic resonance-positron-emission tomography (MR-PET) predicts tumor response to treatment and survival in non-metastatic non-small-cell lung cancer (NSCLC) patients receiving chemoradiotherapy (CRT). METHODS: Patients underwent DCE integrated MR-PET imaging 1 week before CRT. The following parameters were analyzed: primary tumor size, gross tumor volume, maximal standardized uptake value (SUVmax ), total lesion glycolysis (TLG), apparent diffusion coefficient (ADC), volume transfer constant (Ktrans ), reverse reflux rate constant (kep ), extracellular extravascular volume fraction (ve ), blood plasma volume fraction (vp ), and initial area under the time-concentration curve defined over the first 60 s post-enhancement (iAUC60 )...
January 4, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30610355/is-there-a-patient-population-with-squamous-cell-carcinoma-of-the-head-and-neck-region-who-might-benefit-from-de-intensification-of-postoperative-radiotherapy-a-monocentric-retrospective-analysis-of-a-previously-defined-low-risk-patient-population-treated-with
#3
Yonca Onbasi, Sebastian Lettmaier, Markus Hecht, Sabine Semrau, Heinrich Iro, Marco Kesting, Rainer Fietkau, Marlen Haderlein
PURPOSE: The aim of this retrospective study was to evaluate the clinical outcome of a previously defined low-risk patient population with completely resected (R0) squamous cell carcinoma of the oral cavity, oropharynx, larynx (pT1-3, pN0-pN2b), hypopharynx (pT1-2, pN0-pN1), and the indication for postoperative radio(chemo)therapy. PATIENTS AND METHODS: According to predefined criteria, 99 patients with head and neck squamous cell carcinoma (SCC) who were treated at our institution from January 1, 2005 to December 31, 2014, were available for analysis...
January 4, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30610354/comparison-of-68-ga-psma-ligand-pet-ct-versus-conventional-cross-sectional-imaging-for-target-volume-delineation-for-metastasis-directed-radiotherapy-for-metachronous-lymph-node-metastases-from-prostate-cancer
#4
Daniel Walacides, Astrid Meier, Anne Caroline Knöchelmann, Daniele Meinecke, Thorsten Derlin, Frank M Bengel, Tobias L Ross, Hans-Jürgen Wester, Katja Derlin, Markus A Kuczyk, Christoph A J von Klot, Hans Christiansen, Christoph Henkenberens
PURPOSE: To assess the differences in the target volume (TV) delineation of metachronous lymph node metastases between 68  Ga-PSMA ligand PET/CT and conventional imaging in a comparative retrospective contouring study. PATIENTS AND METHODS: Twenty-five patients with biochemical prostate cancer recurrence after primary prostatectomy underwent 68  Ga-PSMA ligand PET/CT in addition to conventional imaging techniques such as CT and/or MR imaging for restaging. All patients were diagnosed with at least one lymph node metastasis...
January 4, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30610353/comment-to-impact-of-postmastectomy-radiotherapy-on-the-outcomes-of-breast-cancer-patients-with-t1-2-n1-disease-an-individual-patient-data-analysis-of-three-clinical-trials
#5
LETTER
Christiane Matuschek, David Krug, Rainer J Klement, René Baumann
No abstract text is available yet for this article.
January 4, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30607453/hyperthermic-chest-wall-re-irradiation-in-recurrent-breast-cancer-a-prospective-observational-study
#6
C De-Colle, N Weidner, V Heinrich, S Brucker, M Hahn, K MacMillan, U Lamprecht, S Gaupp, O Voigt, D Zips
PURPOSE: To prospectively investigate the role of re-irradiation (re-RT) combined with hyperthermia (HT) in a contemporary cohort of patients affected by recurrent breast cancer (RBC). METHODS: Within the prospective registry HT03, patients with resected RBC and previous irradiation were included. Re-RT was applied to the recurrence region with doses of 50-50.4 Gy, with a boost up to 60-60.4 Gy to the microscopically or macroscopically positive resection margins (R1/R2) region...
January 3, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30603857/a-comparison-of-a-brachytherapy-and-an-external-beam-radiotherapy-boost-in-breast-conserving-therapy-for-breast-cancer-local-and-any-recurrences
#7
Isabelle Kindts, Karolien Verhoeven, Annouschka Laenen, Melissa Christiaens, Hilde Janssen, Aline Van der Vorst, Erik Van Limbergen, Caroline Weltens
PURPOSE: Adding a tumour bed boost to whole-breast irradiation in breast-conserving therapy reduces local recurrence rates. The purpose of the present study was to investigate whether the boost technique influences the magnitude of the effect. METHODS: Patients treated with breast-conserving therapy for invasive breast cancer between 2000 and 2007 were included in the analysis. Three groups were considered according to the applied boost technique: electrons, brachytherapy or photons...
January 2, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30564845/low-dose-radiotherapy-mayday-mayday-we-ve-been-hit
#8
EDITORIAL
Oliver J Ott, Oliver Micke, Ralph Mücke, Marcus Niewald, Franz Rödel, Ulrich Schäfer, M H Seegenschmiedt, Meritxell Arenas, Benjamin Frey, Udo S Gaipl
No abstract text is available yet for this article.
December 18, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30564844/-risk-of-second-malignancies-after-platinum-based-chemotherapy-of-testicular-cancer
#9
David Utz, Arndt-Christian Müller
No abstract text is available yet for this article.
December 18, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30552450/-stereotactic-body-radiation-therapy-is-superior-to-sorafenib-in-terms-of-survival-in-patients-with-hepatocellular-carcinoma
#10
Ping Jiang, Jürgen Dunst
No abstract text is available yet for this article.
December 14, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30539195/-genetic-risk-factors-for-a-second-neoplasm-in-children-who-have-survived-a-first-malignant-disease
#11
Martin G Sauer
No abstract text is available yet for this article.
December 11, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30523417/ct-based-dose-recalculations-in-head-and-neck-cancer-radiotherapy-comparison-of-daily-dose-recalculations-to-less-time-consuming-approaches
#12
Simon Wagenblast, Severin Kampfer, Kai J Borm, Stephanie E Combs, Steffi U Pigorsch, Marciana-Nona Duma
BACKGROUND: The goal of this study was to investigate if daily dose recalculations are necessary or if less time-consuming approaches can be used to identify dose differences to the planned dose in patients with head and neck cancers (H&N). METHODS: For 12 H&N patients treated with helical tomotherapy, daily dose calculations were performed retrospectively. Four different summation doses (SuDo) were calculated: DayDo (daily dose calculation), MVCTx2, MVCTx5, and MVCTx10 (dose calculations every second, fifth, and tenth fraction)...
December 6, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30519730/institutional-patient-accrual-volume-and-the-treatment-quality-of-i%C3%A2-125-prostate-seed-implantation-in-a-japanese-nationwide-prospective-cohort-study
#13
Katsumasa Nakamura, Saiji Ohga, Atsunori Yorozu, Shiro Saito, Takashi Kikuchi, Takushi Dokiya, Masanori Fukushima, Hidetoshi Yamanaka
PURPOSE: It is unclear whether experience at high-volume institute improves the treatment quality of prostate seed implantation. The aim of this study was to evaluate the effect of institutional experience on postimplant dosimetric parameters in a nationwide prospective cohort study. METHODS: From July 2005 to June 2007, 2354 patients were registered in the Japanese Prostate Cancer Outcome Study of Permanent I‑125 Seed Implantation (J-POPS), and 1126 patients treated with seed implantation alone were evaluated...
December 5, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30498845/palliative-care-in-everyday-practice-of-radiation-oncologists-results-from-a-web-based-survey-among-medical-members-of-the-german-society-for-radiation-oncology-degro
#14
Janina Fels, Steffi Pigorsch, Hilke Vorwerk, Rita Engenhart-Cabillic, Birgitt van Oorschot
PURPOSE: Little is known about the attitudes of radiation oncologists towards palliative care, about their competences in this field, and about the collaboration with palliative care specialists. Our aim was to close this gap and understand more about the importance of an additional qualification in palliative care. METHODS: Medical members of the German Society for Radiation Oncology (DEGRO) were electronically surveyed during November-December 2016. RESULTS: The survey was emailed successfully to 1110 addressees, whereas a total of 205 questionnaires were eligible for analysis (response rate 18...
November 29, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30478670/impact-of-androgen-deprivation-therapy-on-apparent-diffusion-coefficient-and-t2w-mri-for-histogram-and-texture-analysis-with-respect-to-focal-radiotherapy-of-prostate-cancer
#15
M Daniel, P Kuess, P Andrzejewski, T Nyholm, T Helbich, S Polanec, F Dragschitz, G Goldner, D Georg, P Baltzer
PURPOSE: Accurate prostate cancer (PCa) detection is essential for planning focal external beam radiotherapy (EBRT). While biparametric MRI (bpMRI) including T2-weighted (T2w) and diffusion-weighted images (DWI) is an accurate tool to localize PCa, its value is less clear in the case of additional androgen deprivation therapy (ADT). The aim of this study was to investigate the value of a textural feature (TF) approach on bpMRI analysis in prostate cancer patients with and without neoadjuvant ADT with respect to future dose-painting applications...
November 26, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30478669/linac-based-radiosurgery-or-fractionated-stereotactic-radiotherapy-with-flattening-filter-free-volumetric-modulated-arc-therapy-in-elderly-patients-a-mono-institutional-experience-on-110-brain-metastases
#16
Fabiana Gregucci, Alba Fiorentino, Stefanie Corradini, Vanessa Figlia, Rosario Mazzola, Francesco Ricchetti, Ruggero Ruggieri, Filippo Alongi
AIM: The aim of this study was to analyze the feasibility and clinical results of linear accelerator (linac-)based stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (SFRT) with flattening filter-free (FFF) volumetric modulated arc therapy (VMAT) in elderly patients affected by brain metastases (BMs). PATIENTS AND METHODS: Patients selected for the present analysis were ≥65 years old with a life expectancy of >3 months, a controlled or synchronous primary tumor, and <10 BMs with a diameter <3 cm...
November 26, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30470846/biliary-duct-stenosis-after-image-guided-high-dose-rate-interstitial-brachytherapy-of-central-and-hilar-liver-tumors-a-systematic-analysis-of-102-cases
#17
Maciej Powerski, Susanne Penzlin, Peter Hass, Ricarda Seidensticker, Konrad Mohnike, Robert Damm, Ingo Steffen, Maciej Pech, Günther Gademann, Jens Ricke, Max Seidensticker
OBJECTIVE: Image-guided high-dose-rate interstitial brachytherapy (iBT) with iridium-192 is an effective treatment option for patients with liver malignancies. Little is known about long-term radiation effects on the bile duct system when central hepatic structures are exposed to iBT. This retrospective analysis investigates the occurrence of posthepatic cholestasis (PHC) and associated complications in patients undergoing iBT. MATERIALS AND METHODS: We identified patients who underwent iBT of hepatic malignancies and had point doses of ≥1 Gy to central bile duct structures...
November 23, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30470845/a-fatal-case-of-fournier-s-gangrene-during-neoadjuvant-radiotherapy-for-rectal-cancer
#18
Rainer Johannes Klement, Gabriele Schäfer, Reinhart A Sweeney
PURPOSE: To report the development of an ultimately fatal occurrence of Fournier's gangrene in a rectal cancer patient undergoing neoadjuvant radiotherapy without chemotherapy. METHODS: A 53-year-old male patient with G2 cT3 cN1a cM0 stage IIIB adenocarcinoma of the lower rectum and several comorbidities including ulcerative colitis was treated with 56 Gy to the primary tumor in 28 fractions because he declined the recommended simultaneous chemotherapy. He was also enrolled in the ketogenic diet arm of our KETOCOMP study, so that prospective measurements of blood parameters, quality of life, and body composition were made...
November 23, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30465265/incidence-of-second-primary-cancers-after-radiotherapy-combined-with-platinum-and-or-cetuximab-in-head-and-neck-cancer-patients
#19
Olgun Elicin, Burim Sermaxhaj, Beat Bojaxhiu, Mohamed Shelan, Roland Giger, Daniel Rauch, Daniel M Aebersold
PURPOSE: The second primary cancer (SPC) incidence after treatment with platinum-based chemotherapy and cetuximab in combination with radiotherapy has not been previously reported. Our aim was to compare SPC risk following radiotherapy in combination with these agents for the treatment of head and neck squamous cell carcinoma (HNSCC). METHODS: The charts of 296 cases treated for loco-regionally advanced HNSCC between 2009 and 2015 were retrospectively reviewed for patient, tumor, and procedural characteristics...
November 21, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30443682/impact-of-bladder-volume-on-acute-genitourinary-toxicity-in-intensity-modulated-radiotherapy-for-localized-and-locally-advanced-prostate-cancer
#20
Arne Grün, Michael Kawgan-Kagan, David Kaul, Harun Badakhshi, Carmen Stromberger, Volker Budach, Dirk Böhmer
BACKGROUND AND PURPOSE: To evaluate the effect of changes in bladder volume during high-dose intensity-modulated-radiotherapy (IMRT) of prostate cancer on acute genitourinary (GU) toxicity and prospectively evaluate a simple biofeedback technique for reproducible bladder filling with the aim of reducing acute GU toxicity. METHODS: One hundred ninety-three patients were trained via a biofeedback mechanism to maintain a partially filled bladder with a reproducible volume of 200-300 cc at planning CT and subsequently at each fraction of radiotherapy...
November 15, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
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