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Toxicology and Industrial Health

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https://www.readbyqxmd.com/read/28196457/dermal-absorption-of-fumigant-gases-during-hazmat-incident-exposure-scenarios-methyl-bromide-sulfuryl-fluoride-and-chloropicrin
#1
Sharyn Gaskin, Linda Heath, Dino Pisaniello, John W Edwards, Michael Logan, Christina Baxter
Accidental or intentional releases of toxic gases or vapors are the most common occurrence in hazardous material (HAZMAT) incidents that result in human injuries. The most serious hazard from exposure to gases or vapors is via the respiratory system. Dermal uptake, as a secondary route, is still a concern, most acutely for the unprotected public. There is a limited evidence base describing skin absorption of toxic gases and vapors in HAZMAT exposure scenarios, which are relatively brief compared with traditional test periods for skin absorption studies...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28196456/toxicity-of-internalized-laser-generated-pure-silver-nanoparticles-to-the-isolated-rat-hippocampus-cells
#2
Canan Kursungoz, Sadık Taşkın Taş, Mustafa F Sargon, Yıldırım Sara, Bülend Ortaç
Silver nanoparticles (AgNPs) are the most commonly used nanoparticles (NPs) in medicine, industry and cosmetics. They are generally considered as biocompatible. However, contradictory reports on their biosafety render them difficult to accept as 'safe'. In this study, we evaluated the neurotoxicity of direct AgNP treatment in rat hippocampal slices. We produced pure uncoated AgNPs by a pulsed laser ablation method. NP characterization was performed by Ultraviolet (UV) visible spectrophotometer, scanning electron microscope, transmission electron microscope (TEM) and energy-dispersive X-ray spectroscopy...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28196455/toxicological-perturbations-of-zinc-oxide-nanoparticles-in-the-coelatura-aegyptiaca-mussel
#3
Sohair R Fahmy, Dawlat A Sayed
More research is needed to understand the interactions of nanoparticles (NPs) with aquatic organisms and their mechanism of toxic action. Zinc oxide nanoparticles (ZnONPs) are the most used engineered metal oxide NPs in consumer products. The present study was designed to evaluate the cytotoxicity, genotoxicity and digestive gland (DG) as well as gill histopathology of the freshwater molluscan bivalve Coelatura aegyptiaca following exposure to ZnONPs (2, 10 and 50 mg/L) for 6 consecutive days. Exposure to ZnONPs (10 and 50 mg/L) induced a significant increase in malondialdehyde, superoxide dismutase and nitric oxide with a concomitant decrease in reduced glutathione, glutathione-S-transferase and catalase levels in the haemolymph, DG and gills of the treated mussels...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28162043/chest-ultrasonography-in-health-surveillance-of-asbestos-related-lung-diseases
#4
Andrea Smargiassi, Giuliana Pasciuto, Ilaria Pedicelli, Erminia Lo Greco, Mariarosaria Calvello, Riccardo Inchingolo, Gioacchino Schifino, Patrizio Capoluongo, Pasquale Patriciello, Maurizio Manno, Alfonso Cirillo, Giuseppe Maria Corbo, Gino Soldati, Ivo Iavicoli
OBJECTIVES: Exposure to asbestos fibers can lead to different lung diseases, such as pleural thickening and effusion, asbestosis, mesothelioma, and lung cancer. These diseases are expected to peak in the next few years. The aim of the study was to validate ultrasonography (US) as a diagnostic tool in the management of lung diseases in subjects with a history of occupational exposure to asbestos. METHODS: Fifty-nine retired male workers previously exposed to asbestos were enrolled in the study...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28125953/the-effect-of-tobacco-smoke-exposure-on-generation-of-reactive-oxygen-species-and-cellular-membrane-damage-using-a-co-culture-model-system-of-blood-brain-barrier-with-astrocytes
#5
Seung-Beom Seo, Eun Sang Choe, Kwang-Sik Kim, Soon-Mi Shim
Brain tissue is known to be vulnerable to the exposure by tobacco smoke. Tobacco smoke can induce generation of reactive oxygen species (ROS), causing inflammatory activity and blood-brain barrier (BBB) impairment. The aim of the present study was to investigate the effect of tobacco smoke on cell cytotoxicity, generation of ROS, and cellular membrane damage in astrocytes and BBB using a co-culture system. Cell viability of U373MG cells was reduced in a dose-dependent manner, ranging from 96.7% to 40.3% by tobacco smoke condensate (TSC)...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28073318/effects-of-hydroxyl-functionalized-multiwalled-carbon-nanotubes-on-sperm-health-and-testes-of-wistar-rats
#6
N K Nirmal, K K Awasthi, P J John
Carbon nanotubes (CNTs) are promising candidates for various applications including biomedical purposes. Owing to their remarkable physical, mechanical, electrical and chemical properties, CNTs have become an area of intense research and industrial activity in recent years. Therefore, toxicity and risk assessment studies are becoming increasingly important. The present study was designed to assess the effects of hydroxyl-functionalized multiwalled CNTs (OH-f MWCNTs) on sperm health and testes of adult Wistar rats...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28071526/methylmercury-in-fish-from-the-southern-baltic-sea-and-coastal-lagoons-as-a-function-of-species-size-and-region
#7
Lucyna Polak-Juszczak
BACKGROUND: Methylmercury (MeHg) is a highly toxic compound that traverses the blood-brain barrier with deleterious effects to the central nervous system. Exposure is generally through the ingestion of contaminated fish. Fish are a main source of MeHg. Goals and methods: The aim of this study was to determine the dependence of MeHg concentrations on fish species and age, the percentage of MeHg in total mercury (THg) and risk assessment depending on the size of fish. Assays of THg and MeHg were performed on the muscle tissues of 18 species of fish...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28071525/additive-toxic-effect-of-deltamethrin-and-cadmium-on-hepatic-hematological-and-immunological-parameters-in-mice
#8
Hasibur Rehman, Al Thbiani Aziz, Shalini Saggu, Adam L VanWert, Nahla Zidan, Sundeep Saggu
Exposure to natural and man-made environmental toxins concurrently can pose a greater threat to multiple organs. In the present work, we investigated interactions between deltamethrin (DM) and cadmium (Cd), whose mechanisms of action in humans are poorly understood. Albino mice were randomly divided into four groups, each containing six mice: saline as control, DM-treated, cadmium chloride (CdCl2)-treated, and CdCl2 plus DM treated. After 2 weeks of treatment biochemical and hematological effects, total leukocyte count (TLC), differential leukocyte count, humoral-mediated immune responses, and histopathological studies were conducted...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28092234/retraction-notice
#9
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28092233/editorial
#10
Anthony L Kiorpes
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28092232/retraction-notice
#11
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28092231/retraction-notice
#12
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28092230/octamethylcyclotetrasiloxane-d4
#13
(no author information available yet)
Octamethylcyclotetrasiloxane (D4; CAS No. 556-67-2) is used as a monomer in the manufacture of polymeric materials, which are widely used in various industrial and/or medical applications, such as breast implants. D4 has a relatively low order of toxicity following acute administration via the oral, dermal, and inhalation routes of exposure and is not considered to be a dermal or eye irritant or to be a dermal sensitizer. There is no appreciable dermal absorption of D4 based on results from in vivo and in vitro studies...
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/28092229/decamethylcyclopentasiloxane-d5
#14
(no author information available yet)
Decamethylcyclopentasiloxane (D5; CAS No. 541-02-6) is a precursor in the production of siloxane polymers for industry and medicine and is a carrier ingredient in many toiletries and cosmetics. D5 has a relatively low order of toxicity following acute administration via the oral, dermal, and inhalation routes of exposure. It is not considered to be a dermal or eye irritant or a dermal sensitizer. There is no appreciable dermal absorption of D5 based on results from in vivo and in vitro studies. It has not been shown to be genotoxic/mutagenic when tested in a number of short-term in vitro and in vivo assays and did not cause reproductive or developmental toxicity in rats...
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/27495248/carbon-monoxide-poisoning-cases-presenting-with-non-specific-symptoms
#15
Turgut Deniz, Hayati Kandis, Oguz Eroglu, Harun Gunes, Meral Saygun, Ismail Hamdi Kara
Carbon monoxide (CO) is a colourless and odourless gas appearing as a result of incomplete combustion of carbon-containing fuels. Many domestic or occupational poisonings are caused by CO exposure. Malfunctioning heating systems, improperly ventilated motor vehicles, generators, grills, stoves and residential fires may be listed in the common sources of CO exposure. The aim of this study was to emphasize the significance of early diagnosis of CO poisoning with non-invasive measurement of CO levels of the patients with non-specific symptoms using a pulse oximeter device in the triage...
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/23344823/retracted-median-lethal-concentration-of-two-pesticides-diazinon-and-deltamethrin-on-tra-catfish-pangasius-hypophthalmus-siluroidei-pangasiidae
#16
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/22914264/retracted-detection-of-lc50-noec-and-loec-of-some-heavy-metals-mercury-plumb-and-zinc-in-freshwater-fish-roach-rutilus-rutilus
#17
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/22914263/retracted-detection-of-lc50-of-crude-oil-in-silver-carp-hypophthalmicthys-molitrix-common-carp-cyprinus-carpio-and-caspian-roach-rutilus-rutilus-caspicus
#18
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/22903180/retracted-effects-of-nanometer-sized-silver-materials-on-survival-response-of-caspian-roach-rutilus-rutilus-caspicus
#19
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/22577127/retracted-effects-of-crude-diesel-oil-on-the-enzymatic-defenses-of-the-great-sturgeon-huso-huso
#20
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Toxicology and Industrial Health
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