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Journals Veterinary Clinics of North Am...

Veterinary Clinics of North America. Equine Practice

https://read.qxmd.com/read/37574382/overview-of-equine-stem-cells-sources-practices-and-potential-safety-concerns
#21
REVIEW
Thomas G Koch, Alexander G Kuzma-Hunt, Keith A Russell
Over the past 2 decades, equine veterinarians are turning increasingly to stem cell therapies to repair damaged tissues or to promote healing through modulation of the immune system. Research is ongoing into optimizing practices associated with stem cell product transport, dosage, and administration. Culture-expanded equine mesenchymal stem cell therapies seem safe, even when used allogeneically, but various safety concerns should be considered. Stem cells and cellular reprogramming tools hold great promise for future equine therapies...
August 11, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37558508/introduction-to-equine-biologic-and-regenerative-therapies
#22
REVIEW
Lindsey Boone, John Peroni
Regenerative medicine is defined as the process of replacing or regenerating cells, tissues, or organs to restore or establish normal function. The use of regenerative medicine in equine practice to treat injured musculoskeletal tissues with limited capacity for intrinsic healing is growing. This article provides the practitioner with a brief and basic overview of the regenerative products currently used in equine practice.
August 7, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37550128/considerations-for-the-use-of-biologic-and-regenerative-therapies-in-equine-practice
#23
EDITORIAL
Lauren V Schnabel
No abstract text is available yet for this article.
August 5, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37550127/advances-in-regional-vascular-injection-techniques-for-the-delivery-of-stem-cells-to-musculoskeletal-injury-sites
#24
REVIEW
Mathieu Spriet, Betsy Vaughan, Myra Barrett, Larry D Galuppo
Vascular injections of stem cells are a pertinent alternative to direct intralesional injections when treating multiple or extensive lesions or with lesions impossible to reach directly. Extensive research using stem cell tracking has shown that intra-arterial injections without the use of a tourniquet should be preferred over venous or arterial regional limb perfusion techniques using a tourniquet. The median artery is used for the front limbs and the cranial tibial artery for the hind limbs. Proper efficacy studies are still lacking but early clinical work seems promising...
August 5, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37550126/equine-platelet-rich-plasma
#25
REVIEW
Taralyn M McCarrel
Platelet-rich plasma (PRP) is an orthobiologic therapy composed of platelets, leukocytes, red blood cells, and plasma proteins. PRP has been used for 20 years, but progress determining efficacy has been slow. The definitions and classification of PRP are reviewed, and the use of PRP for tendon, ligament, and joint disease is discussed with a focus on findings of basic science and clinical studies, platelet activation, concurrent administration of nonsteroidal anti-inflammatory drugs, and treatment complications...
August 5, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37482520/advances-in-imaging-techniques-to-guide-therapies-and-monitor-response-to-the-treatment-of-musculoskeletal-injuries
#26
REVIEW
Caitlyn R Horne, Sara Tufts
Continual advancements in diagnostic imaging have allowed for more accurate and complete diagnoses of injuries in the performance horse. The use of several different imaging tools has further allowed the equine sports medicine clinician to more carefully direct treatment options, monitor response to therapy and guide rehabilitation recommendations. The advancements in diagnostic imaging and novel treatment options have led to the improvement in the overall prognosis of many injuries that affect the horse and their performance...
July 21, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37442732/interactions-between-biologic-therapies-and-other-treatment-modalities
#27
REVIEW
Aimee C Colbath, Christopher W Frye
Biologic therapies are becoming increasingly utilized by veterinarians. The literature regarding the interaction of biologic therapies with other therapeutics is still in its infancy. Initial studies have examined the effects of exercise, stress, various pharmaceutical interventions, extracorporeal shockwave, therapeutic laser, and hyperbaric oxygen on biologic therapies. Continued research is imperative as owners and veterinarians increasingly choose a multimodal approach to injury and illness. Further, understanding the effects of concurrently administered treatments and pharmaceuticals as well as the health status of the horse is imperative to providing the optimal therapeutic outcome...
July 11, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37442731/use-of-biologics-and-stem-cells-for-wound-healing-in-the-horse
#28
REVIEW
Rebecca M Harman, Aarthi Rajesh, Gerlinde R Van de Walle
Treatment of skin wounds is a high priority in veterinary medicine because healthy uncompromised skin is essential for the well-being of horses. Stem cells and other biologic therapies offer benefits by reducing the need for surgical procedures and conventional antibiotics. Evidence from in vitro studies and small in vivo trials supports the use of equine stem cells and biologics for the treatment of acute and chronic cutaneous wounds. Larger clinical trials are warranted to better evaluate the regenerative and immunological responses to these treatments...
July 11, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37442730/use-of-biologics-and-stem-cells-in-equine-ophthalmology
#29
REVIEW
Brian Christopher Gilger
Regenerative therapy and biologics have the promise to treat equine ocular surface diseases, including corneal ulceration or immune-mediated keratitis, or intraocular diseases such as uveitis. The use of blood-derived products such as serum or platelet-rich plasma, mesenchymal stem cells, or amniotic membrane grafts may be beneficial for the treatment of ulcerative and chronic keratitis in horses. Furthermore, the use of stem cells or gene therapy has promise for the treatment of Intraocular diseases such as equine recurrent uveitis by providing efficacious, practical, and long-term therapy for these blinding diseases...
July 11, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37442729/antimicrobial-properties-of-equine-stromal-cells-and-platelets-and-future-directions
#30
REVIEW
Lynn M Pezzanite, Lyndah Chow, Steven W Dow, Laurie R Goodrich, Jessica M Gilbertie, Lauren V Schnabel
Increasing antimicrobial resistance in veterinary practice has driven the investigation of novel therapeutic strategies including regenerative and biologic therapies to treat bacterial infection. Integration of biological approaches such as platelet lysate and mesenchymal stromal cell (MSC) therapy may represent adjunctive treatment strategies for bacterial infections that minimize systemic side effects and local tissue toxicity associated with traditional antibiotics and that are not subject to antibiotic resistance...
July 11, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37442728/equine-bone-marrow-aspirate-concentrate
#31
REVIEW
Lisa A Fortier
Bone marrow concentrate is generated by centrifugation of bone marrow aspirate. It contains mesenchymal stromal cells, anabolic chemokines/cytokines, and supraphysiological concentrations of interleukin-1 receptor antagonist protein (IL-1RA). It is an effective treatment for osteoarthritis or desmitis, or as an adjunct in surgery to enhance bone or cartilage repair.
July 11, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37268523/epidemiology-of-colic-current-knowledge-and-future-directions
#32
REVIEW
Alexandra Gillen, Debra Catherine Archer
Epidemiologic studies are essential for the generation of evidence-based, preventive health care strategies. This includes ways to minimize colic risk and assist informed decision making concerning diagnosis, treatment, and likely outcomes. It is important to consider that colic is not a simple "disease" but is a syndrome of abdominal pain that encompasses multiple different disease processes, and which is multifactorial in nature. This review focuses on prevention and diagnosis of colic, including specific forms of colic, communications with owners/carers concerning colic risk and management, and areas of future research...
May 31, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37258390/neonates-and-periparturient-mares-tips-and-tricks-for-diagnosis-and-management
#33
REVIEW
Nathan Slovis, Leci Irvin
Colic is a common presenting complaint in foals. Unfortunately, evaluation of foals with colic can be difficult due to the common clinical presentation of acute abdominal pain attributable to a wide variety of disorders and a broad range of etiologies. Similar to foals, colic is one of the most common diseases of pregnant and periparturient mares. Several conditions are unique or occur more commonly in broodmares. This article reviews the most commonly encountered types of colic events in neonatal foals and periparturient mares, how to correctly diagnose these conditions, as well as details concerning appropriate medical management and/or surgical intervention...
May 29, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37225556/equine-colic-can-we-do-better
#34
EDITORIAL
Louise L Southwood
No abstract text is available yet for this article.
May 22, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37198055/role-of-laparoscopy-in-diagnosis-and-management-of-equine-colic
#35
REVIEW
Ann Martens, Hanna Haardt
Laparoscopy can be valuable in the diagnosis and treatment of specific types of colic in horses. Most commonly, it is used for horses with chronic recurrent colic for further diagnosis, such as by taking biopsies or to perform treatment. Laparoscopy is also often used for prevention of colic, for example, by closing the nephrosplenic space or epiploic foramen. There are fewer indications for laparoscopy in acute colic, though in some cases the technique can be useful for diagnosis, after which the procedure is converted to a hand-assisted laparoscopy...
May 16, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37169621/current-topics-in-medical-colic
#36
REVIEW
Michelle Henry Barton, Gayle D Hallowell
The list of medical causes of acute or chronic colic in horses is extensive. The purpose of this article is to review 4 medical causes of equine colic with a focus on newer trends in treatment. The 4 topics selected include gastric impaction, gastric glandular disease, colon displacement, and inflammatory bowel disease.
May 9, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37169620/critical-care-of-the-colic-patient-monitoring-fluid-therapy-and-more
#37
REVIEW
Charlie Barton, Diana M Hassel
A successful outcome to management of the critical colic patient is highly dependent on how the patient is monitored and treated, particularly, in the perioperative period. In this article, we will provide an update on monitoring techniques, advances in fluid therapy, nutrition management and pharmacotherapeutic agents, inclusive of pain monitoring and management, prokinetics, and management of systemic inflammatory response syndrome and the hypercoagulable state.
May 9, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37169619/colic-surgery-recent-updates
#38
REVIEW
Maia R Aitken
The following article provides an overview of the last 5 years of research and innovation within the field of equine colic surgery, focusing on new techniques, new or recently described lesions, prevention of lesion recurrence or postoperative complications, and updates in prognoses. Early surgical intervention is an important factor in horse survival.
May 9, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37169618/abdominal-sonographic-evaluation-in-the-field-at-the-hospital-and-after-surgery
#39
REVIEW
Cristobal Navas de Solis, Michelle Coleman
Abdominal sonography is currently a routine procedure in the evaluation of colic in the horse. This imaging technique is used in both the assessment of the horse presented in the emergency setting with acute colic and the assessment of the horse presented for chronic or recurrent colic in the nonemergency setting. Sonography for colic evaluation is used by specialists in different disciplines and by general practitioners in the ambulatory and hospital settings. In this review, we will focus on indications and clinical interpretation of findings as well as recent developments in abdominal sonography...
May 9, 2023: Veterinary Clinics of North America. Equine Practice
https://read.qxmd.com/read/37121786/what-is-the-microbiota-and-what-is-its-role-in-colic
#40
REVIEW
Carolyn E Arnold, Rachel Pilla
The fecal microbiome of the horse is reflective of the large colon and plays an important role in the health of the horse. The microbes of the gastrointestinal tract digest fiber and produce energy for the host. Healthy horses have Firmicutes, Bacteroidetes, and Verrucromicrobia as the most common phyla. During gastrointestinal disease such as colic or colitis, the microbiome shows less diversity and changes in bacterial community composition.
April 28, 2023: Veterinary Clinics of North America. Equine Practice
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