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Canadian Journal of Cardiology

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https://www.readbyqxmd.com/read/28807521/erratum
#1
(no author information available yet)
No abstract text is available yet for this article.
August 11, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941612/recipient-atrial-fibrillation-manifesting-as-an-irregular-monomorphic-atrial-tachycardia-in-the-donor-heart
#2
Nicolas Johner, Mehdi Namdar, Andréa Buttu, Sophie Perenet, Philippe Meyer, Dipen C Shah
A 63-year-old man presented with a 1-year history of atrial tachycardia (AT) 6 years after orthotopic heart transplantation with bicaval anastomosis. Twelve-lead electrocardiogram showed monomorphic AT with isoelectric intervals across all leads and strikingly irregular PP intervals. At electrophysiology study, the native left atrium's rhythm was atrial fibrillation (AF) while the donor atria exhibited centrifugal activation of irregular cycle length originating from a site along the left atrial anastomosis...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941611/quality-of-acute-myocardial-infarction-care-in-canada-a-10-year-review-of-30-day-in-hospital-mortality-and-30-day-hospital-readmission
#3
Dat T Tran, Robert C Welsh, Arto Ohinmaa, Nguyen X Thanh, Akshay Bagai, Padma Kaul
BACKGROUND: The recently released Canadian cardiac care quality indicators include 30-day in-hospital mortality and readmission rates after percutaneous coronary intervention (PCI) and isolated coronary artery bypass grafting (CABG). We examined long-term trends and provincial variations in these outcomes among acute myocardial infarction (AMI) patients. METHODS: We included patients aged 18 years and older who were hospitalized with a primary diagnosis of AMI between 2004 and 2013 in all Canadian provinces except Quebec...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941610/scavenger-receptor-lox1-genotype-predicts-coronary-artery-disease-in-patients-with-familial-hypercholesterolemia
#4
Martine Paquette, Robert Dufour, Alexis Baass
BACKGROUND: Familial hypercholesterolemia (FH) is a monogenic disease associated with elevated low-density lipoprotein (LDL) cholesterol and oxidized LDL (oxLDL) leading to premature cardiovascular disease. Lectin-like oxLDL receptor-1 (LOX1) is one of the major contributors of oxLDL uptake and degradation in macrophages, which leads to foam cell formation and the development of atherosclerosis. This study investigated the effect of the rs11053646 genotype of the oxidized low-density lipoprotein receptor 1 (OLR1) gene on coronary artery disease (CAD) risk in a cohort of FH patients...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941609/association-of-apolipoproteins-b-and-a-1-with-markers-of-vascular-health-or-cardiovascular-events
#5
Yiming M Zhu, Subodh Verma, Marinda Fung, Matthew J McQueen, Todd J Anderson, Eva M Lonn
BACKGROUND: Apolipoprotein B (apoB) and apolipoprotein A-1 (apoA-1) are markers of lipoprotein metabolism. Although their relationship to cardiovascular disease has been well documented, little is known regarding their correlation to measures of vascular structure and function. This study was conducted to investigate the relationship between apoA-1, apoB, and measures of vascular function, as well their relationship to adverse cardiovascular events. Moreover, we evaluated whether apoB or the apoB/apoA-1 ratio was more closely related to vascular markers than was low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (non-HDL-C)...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941608/economic-evaluation-of-left-ventricular-assist-devices-for-patients-with-end-stage-heart-failure-who-are-ineligible-for-cardiac-transplantation
#6
Derek S Chew, Braden Manns, Robert J H Miller, Nakul Sharma, Derek V Exner
BACKGROUND: Continuous flow (CF) left ventricular assist devices (LVADs) improve survival in end-stage heart failure patients who are ineligible for cardiac transplantation. Their use in this population (referred to as destination therapy) is increasing in many countries, yet they are not routinely funded for this indication in Canada. We assessed the cost-effectiveness of destination therapy CF-LVADs from the perspective of the Canadian health care payer. METHODS: A Markov model was used to project the outcomes and costs of 2 treatment pathways, CF-LVAD implantation and medical management alone, in an end-stage heart failure patient cohort ineligible for transplantation...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941607/impact-of-left-ventricular-vs-biventricular-pacing-on-reverse-remodelling-insights-from-the-evaluation-of-resynchronization-therapy-for-heart-failure-earth-trial
#7
Sabah Skaf, Bernard Thibault, Paul Khairy, Eileen O'Meara, Annik Fortier, Halyna V Vakulenko, Céline Pitre, Michel White, Anique Ducharme
BACKGROUND: Studies comparing biventricular (BiV) cardiac resynchronization therapy (CRT) and left ventricular (LV) pacing alone have yielded conflicting results. We recently reported the results of the Greater Evaluation of Resynchronization Therapy for Heart Failure (GREATER-EARTH) trial demonstrating similar clinical benefits of BiV and LV-CRT on exercise tolerance. We report the prespecified secondary outcomes of the GREATER-EARTH trial, comparing the impact of BiV vs LV-CRT on structural and biochemical cardiac remodelling...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941606/new-developments-in-hypertrophic-cardiomyopathy
#8
REVIEW
Robert M Cooper, Claire E Raphael, Max Liebregts, Nandan S Anavekar, Josef Veselka
Hypertrophic cardiomyopathy is the leading cause of sudden death in young individuals and an important cause of heart failure at any age. In this review we discuss advances in investigation and management of this heterogenous disease. Improved cardiac imaging has allowed us to detail many of the structural abnormalities whereas the use of new techniques, predominantly in cardiac magnetic resonance imaging, has given us a greater insight in to tissue architecture, mechanism of contractile abnormalities, and function...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941605/prevention-of-left-ventricular-thrombus-formation-and-systemic-embolism-after-anterior-myocardial-infarction-a%C3%A2-systematic-literature-review
#9
REVIEW
Alexandra Bastiany, Marie-Eve Grenier, Alexis Matteau, Samer Mansour, Benoit Daneault, Brian J Potter
BACKGROUND: Anterior myocardial infarction (MI) with apical dysfunction is associated with an increased risk of left ventricular thrombus (LVT) formation and systemic embolism (SE). However, the role for prophylactic anticoagulation in current practice is a matter of debate. METHODS: We conducted a systematic review of peer-reviewed original articles in either English or French on the benefit of combining anticoagulation with standard therapy for the prevention of LVT/SE after MI by searching PubMed, Ovid/MedLine/Embase, the Cochrane Library, and Google Scholar...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941604/current-risk-of-contrast-induced-acute-kidney-injury-after-coronary-angiography-and-intervention-a-reappraisal-of-the-literature
#10
Lorenzo Azzalini, Luciano Candilio, Peter A McCullough, Antonio Colombo
Contrast-induced acute kidney injury (CI-AKI) is the acute impairment of renal function further to the intravascular administration of iodinated contrast media, and occurs most frequently after coronary angiography, percutaneous coronary intervention, and contrast-enhanced computed tomography. CI-AKI has been associated with the development of acute renal failure, worsening of chronic kidney disease, requirement for dialysis, prolonged hospital stay, and higher mortality rates and health care costs. Recently, a number of studies suggested that contrast media exposure might not be the causative agent in the occurrence of acute kidney injury, particularly in stable patients who receive small to moderate amounts of contrast media...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28870471/challenging-occam-s-razor-an-unusual-combination-of-sarcoidosis-and-amyloidosis-the-value-of-cardiac-magnetic-resonance-imaging-in-infiltrative-cardiomyopathies
#11
Eva Nyktari, Vassilios S Vassiliou, Monika Arzanauskaite, Peter Gatehouse, Andreas Greiser, Ashutosh Wechalekar, Janet Gilbertson, Iain Pierce, Rakesh Sharma, Raad Mohiaddin
We describe the case of a 66-year old woman with the extremely rare combination of sarcoidosis and amyloidosis (light chain) and the important role of cardiovascular magnetic resonance imaging to differentiate between these 2 infiltrative diseases. Myocardial characterization with T1 mapping can improve disease detection, especially in overlap cases, and possibly obviate the need for cardiac biopsy.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28867265/implantable-cardioverter-defibrillator-implantation-rates-after-out-of-hospital-cardiac-arrest-are-the-rates-guideline-concordant
#12
Edwin C Ho, Sheldon Cheskes, Paul Angaran, Laurie J Morrison, Theresa Aves, Cathy Zhan, Dennis T Ko, Paul Dorian
BACKGROUND: Clinical practice guidelines recommend implantable cardioverter defibrillators (ICDs) for the secondary prevention of sudden death after a cardiac arrest not from a reversible cause, but "real world" implantation rates are not well described. METHODS: Adults with out of hospital cardiac arrest attended by Emergency Medical Services are captured in the Toronto Regional RescuNET database. We analyzed those who survived to hospital discharge and collected data on age, sex, initial rhythm, ST-elevation myocardial infarction (STEMI) on presenting electrocardiogram (ECG), in-hospital revascularization, neurologic status (Modified Rankin Scale [MRS]) at discharge, and admission hospital type...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28867264/implantable-cardioverter-defibrillators-in-sudden-cardiac-death-survivors-are-we-doing-all-we-can
#13
EDITORIAL
Ratika Parkash, Anthony S L Tang
No abstract text is available yet for this article.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28867263/effects-of-hyperthyroidism-on-coronary-artery-disease-a%C3%A2-computed-tomography-angiography-study
#14
Christoph Beyer, Fabian Plank, Guy Friedrich, Matthias Wildauer, Gudrun Feuchtner
BACKGROUND: Changes in thyroid hormone concentration can negatively affect the cardiovascular system. Subclinical hyperthyroidism has been linked to an increase of cardiovascular heart disease, however, clinical effects and significance are still uncertain. Therefore, we analyzed coronary computed tomography angiographies of patients with overt and subclinical hyperthyroidism for quantitative parameters and plaque morphology. METHODS: Seven hundred forty-four (47...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28867262/persistent-hypoxemia-after-acute-myocardial-infarction-an-unexpected-culprit
#15
António Tralhão, Pedro Freitas, Gustavo Rodrigues, Hugo Café, António Miguel Ferreira, Henrique Mesquita Gabriel, Luís Bruges, Carlos Aguiar, Jorge Ferreira
Hypoxemia after myocardial infarction (MI) is usually explained by common culprits, including congestive heart failure, pre-existing lung disease, and pulmonary infection. We report a case of a 60-year-old woman who experienced severe persistent hypoxemia caused by a patent foramen ovale in the setting of anterior MI complicated by a contained left ventricular rupture.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28867261/histologically-proven-myocardial-carcinoid-metastases-the-value-of-multimodality-imaging
#16
Annina A Studer Bruengger, Kshama Wechalekar, Rajdeep Khattar, Stuart D Rosen, Jan Lukas Robertus, Ian Chau, Daniel Morganstein, Ulrich Rosendahl, Alexander Lyon, Raad Mohiaddin
We present a case of a patient with intramyocardial metastases from a carcinoid tumor. These findings were detected using cardiovascular magnetic resonance imaging, with functional metabolic activity analyzed using nuclear imaging and confirmed by histologic findings at surgical biopsy. This case highlights the value of cardiovascular magnetic resonance imaging and the importance of multimodality imaging.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28866078/utility-of-unfractionated-heparin-in-transradial-cardiac-catheterization-a-systematic-review-and-meta-analysis
#17
REVIEW
Matthias Bossard, Shamir R Mehta, Robert C Welsh, Kevin R Bainey
BACKGROUND: Unfractionated heparin (UFH) is purported to reduce the risk of radial artery occlusion (RAO) after transradial cardiac catheterization. However, the efficacy and optimal dose remain unclear. This meta-analysis evaluates the safety and efficacy of UFH in this context. METHODS: MEDLINE, EMBASE, ISI Web of Science, and the Cochrane Registry were searched from 1948-May 2017. Studies investigating UFH for reducing RAO in transradial coronary catheterization were included...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28866077/importance-of-optimization-of-cardiovascular-risk-factors-and-lifestyle-behaviours
#18
EDITORIAL
Todd J Anderson
No abstract text is available yet for this article.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28866076/score-of-adherence-to-2016-european-cardiovascular-prevention-guidelines-predicts-cardiovascular-and-all-cause-mortality-in-the-general-population
#19
Emilie Bérard, Vanina Bongard, Bernadette Haas, Jean Dallongeville, Marie Moitry, Dominique Cottel, Jean-Bernard Ruidavets, Jean Ferrières
BACKGROUND: Guidelines on cardiovascular (CV) disease prevention promote healthy lifestyle behaviours and CV risk factor control to reduce CV risk. The effect of adherence to these guidelines on CV and all-cause mortality is not well known. METHODS: We assessed the effect of baseline adherence to "2016 European Guidelines on CV Disease Prevention in Clinical Practice" on long-term CV and all-cause mortality in a sample recruited from the French general population...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28866075/between-disease-causing-and-an-innocent-bystander-the-role-of-titin-as-a-modifier-in-hypertrophic-cardiomyopathy
#20
EDITORIAL
Brenda Gerull
No abstract text is available yet for this article.
October 2017: Canadian Journal of Cardiology
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