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Canadian Journal of Cardiology

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https://www.readbyqxmd.com/read/28669698/the-curious-incident-of-spotty-calcium-in-unstable-atherosclerotic-plaque
#1
EDITORIAL
Gary S Mintz
No abstract text is available yet for this article.
May 25, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28666616/the-cost-of-frailty-in-cardiac-surgery
#2
EDITORIAL
Bobby Yanagawa, David A Latter, Paul W M Fedak, Charles Cutrara, Subodh Verma
No abstract text is available yet for this article.
May 25, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28666615/aging-well-in-an-era-of-high-tech-cardiovascular-care
#3
EDITORIAL
Michelle M Graham, Christopher S Simpson
No abstract text is available yet for this article.
May 19, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28666617/long-term-follow-up-of-the-implementation-of-a-venous-thromboembolism-prophylaxis-order-set-on-a-cardiology-ward-still-a-surprising-result
#4
LETTER
Christopher Hayes, William F McIntyre, Charlene White, Giuseppe Alleta, Lillian Koley, Colette M Seifer
No abstract text is available yet for this article.
May 13, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28669697/transfemoral-lotus-valve-implantation-for-treatment-of-postendocarditis-stentless-prosthesis-degeneration-with-pure-aortic-regurgitation
#5
Marco B Ancona, Francesco Giannini, Antonio Mangieri, Damiano Regazzoli, Vittorio Romano, Manuela Giglio, Azeem Latib, Antonio Colombo, Matteo Montorfano
No abstract text is available yet for this article.
May 11, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28673761/primary-percutaneous-coronary-intervention-as-treatment-for-st-elevation-myocardial-infarction-in-a-centenarian-choosing-carefully
#6
Justin M Cloutier, Shelley Zieroth, Basem Elbarouni
We report on a 105-year-old woman presenting with inferior ST-elevation myocardial infarction (STEMI). She was managed with primary percutaneous intervention (PCI) to the right coronary artery with a single bare-metal stent. There were no acute complications, although she experienced delirium and functional decline requiring prolonged hospital admission. She was discharged home and celebrated her 106th birthday. This report describes the oldest centenarian with STEMI found in the literature and managed with PCI...
May 8, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28669702/incidence-and-prognostic-implications-of-late-bleeding-after-myocardial-infarction-or-unstable-angina-according-to-treatment-strategy
#7
Miriam Brinkert, Danielle A Southern, Matthew T James, Merrill L Knudtson, Todd J Anderson, François Charbonneau
BACKGROUND: Bleeding complications accompanying coronary revascularization are associated with increased mortality; however, few data are available on subsequent bleeding risk. We used administrative data to assess the incidence of late bleeding events in patients with acute coronary syndrome (ACS) according to treatment allocation. METHODS: The cohort and bleeding events were identified through the Canadian Institute for Health Information discharge abstract database...
May 5, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28669701/comparative-evaluation-of-2-hour-rapid-diagnostic-algorithms-for-acute-myocardial-infarction-using-high-sensitivity-cardiac-troponin-t
#8
Andrew D McRae, Grant Innes, Michelle Graham, Eddy Lang, James E Andruchow, Hong Yang, Yunqi Ji, Shabnam Vatanpour, Danielle A Southern, Dongmei Wang, Isolde Seiden-Long, Lawrence DeKoning, Peter Kavsak
BACKGROUND: Symptoms of acute coronary syndrome account for a large proportion of emergency department (ED) visits and hospitalizations. High-sensitivity troponin can rapidly rule out or rule in acute myocardial infarction (AMI) within a short time of ED arrival. We sought to validate test characteristics and classification performance of 2-hour high-sensitivity troponin T (hsTnT) algorithms for the rapid diagnosis of AMI. METHODS: We included consecutive patients from 4 academic EDs with suspected cardiac chest pain who had hsTnT assays performed 2 hours apart (± 30 minutes) as part of routine care...
May 3, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28669700/cuff-artifact-j-curve-and-application-of-hypertension-guidelines-in-the-elderly
#9
LETTER
J David Spence
No abstract text is available yet for this article.
May 3, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28666618/troubleshooting-cardiac-resynchronization-therapy-in-nonresponders
#10
Sumandeep Dhesi, Evan Lockwood, Roopinder K Sandhu
Heart failure (HF) is a critical health issue. Despite the advancements in pharmacotherapy, HF-related morbidity and mortality remains high. Cardiac resynchronization therapy (CRT) has been revolutionary in medically refractory, symptomatic HF patients with reduced ejection fraction and a prolonged, abnormal QRS complex. Although CRT affects electromechanical dys-synchrony resulting in favourable ventricular remodelling, improved functional capacity and clinical outcomes with fewer HF hospitalizations and better survival, the response to CRT is not uniform...
April 23, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668149/a-novel-technique-for-prosthetic-valve-retrieval-after-transcatheter-aortic-valve-embolization
#11
Francesco Giannini, Neil Ruparelia, Francesca Del Furia, Vittorio Romano, Marco Ancona, Antonio Mangieri, Damiano Regazzoli, Azeem Latib, Cosmo Godino, Francesco Ancona, Luciano Candilio, Richard Jabbour, Antonio Colombo, Matteo Montorfano
Although the rate of procedural complications during transcatheter aortic valve implantation has decreased because of technological advancement and increased operator experience, device embolization remains a rare but potentially fatal complication, even with new generation devices. We report, to our knowledge, the first case of Portico valve (St Jude Medical, Minneapolis, MN) migration despite apparent optimal initial implantation depth, which was retrieved using a novel strategy after failure of a traditional retrieval technique...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668148/large-left-ventricular-aneurysm-and-multifocal-myocardial-involvement-in-a-patient-with-systemic-sclerosis
#12
Luca Olivotti, Deborah Cosmi, Annamaria Nicolino, Luigi Martinelli, Shahram Moshiri, Gian Battista Danzi
A 43-year-old man with systemic sclerosis and chest pain had negative T waves in precordial electrocardiographic leads. The echocardiogram showed a large left ventricular apical accessory chamber. The coronary arteries were normal. Cardiac magnetic resonance imaging (MRI) showed a large fibrotic aneurysm and a small patch of midwall late enhancement in the septum. The aneurysm was surgically removed. At the 8-month follow-up, cardiac MRI showed the appearance of a new nodular lesion in the anterior wall, causing a localized wall motion abnormality...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668147/acute-myocardial-infarction-in-a-young-girl-with-nephrotic-syndrome-a-case-report-and-literature-review
#13
Yan Zhao, Wenhua Su, Shiqi Liu, Qian Huo, Hong Zhang
Acute myocardial infarction is not a very rare complication of nephrotic syndrome. The pathogenesis of ischemic heart disease among patients with nephrosis is commonly thrombosis, whereas atherosclerosis is rare, especially in young individuals. In this case report, we present a 15-year-old girl with nephrotic syndrome who had acute non-ST-elevation myocardial infarction secondary to atherosclerosis of the 3 coronary arteries.
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668146/a-rare-case-of-cardiac-melanoma-mimicking-hypertrophic-cardiomyopathy
#14
Imke Friedel, Wolfgang Burchert, Dieter Horstkotte, Lothar Faber
A 40-year-old female patient with a remote history of a malignant melanoma treated with curative intent presented with the diagnosis of hypertrophic cardiomyopathy (HCM) made at another hospital. Further diagnostic workup included positron emission tomography/computed tomography, which revealed that the HCM phenotype was produced by cardiac involvement of metastatic melanoma. For this reason, the primary diagnosis of HCM had to be retracted and melanoma-specific antineoplastic treatment was initiated.
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668145/modifiable-risk-factors-in-atrial-fibrillation-the-role-of-alcohol-obesity-and-sleep-apnea
#15
Kiran Sidhu, Anthony Tang
Atrial fibrillation (AF) is a common arrhythmia affecting a growing number of Canadians. Traditional risk factors, such as hypertension, diabetes, and valvular disease, are often present in older patients with AF. Modifiable risk factors should also be sought in patients presenting with new-onset AF. Obesity is a rapidly growing epidemic in Canada. Emerging evidence is linking obesity and the often coexistent obstructive sleep apnea with an increased incidence of AF. Alcohol intake can also predispose to the development of AF...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668144/a-practical-guide-to-the-use-of-glucose-lowering-agents-with-cardiovascular-benefit-or-proven-safety
#16
David Fitchett, Alice Cheng, Kim Connelly, Ronald Goldenberg, Shaun G Goodman, Lawrence A Leiter, Eva Lonn, Breay Paty, Paul Poirier, James Stone, David Thompson, Jean-Francois Yale, G B John Mancini
Patients with type 2 diabetes continue to have a high residual risk for cardiovascular events despite intensive risk factor modification. Recent clinical trials have shown that the antihyperglycemic agents empagliflozin and liraglutide reduce cardiovascular events. Other drugs have been shown to have cardiovascular safety. With glucose-lowering agents proven to reduce adverse cardiovascular outcomes, many cardiologists have begun to prescribe or recommend glucose-lowering agents. Other cardiologists are not yet comfortable with this role because they are not accustomed to initiating these drugs...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668143/prognosis-impact-of-frailty-assessed-by-the-edmonton-frail-scale-in-the-setting-of-acute-coronary-syndrome-in-the-elderly
#17
Stéphanie Blanco, Jean Ferrières, Vanina Bongard, Olivier Toulza, Fatia Sebai, Sophie Billet, Caroline Biendel, Olivier Lairez, Thibault Lhermusier, Nicolas Boudou, Francisco Campelo-Parada, Jérôme Roncalli, Michel Galinier, Didier Carrié, Meyer Elbaz, Frédéric Bouisset
BACKGROUND: Elderly patients represent a large proportion of patients admitted for acute coronary syndrome (ACS). Whether frailty-defined as a biological syndrome that reflects a state of decreased physiological reserve and vulnerability to stressors-may impact the clinical outcomes in this population remains unclear. We aimed to determine the prevalence of frailty and its impact on mortality in patients aged ≥ 80 years admitted for ACS. METHODS: This prospective observational study was conducted in patients aged 80 years or older admitted to a tertiary hospital for ACS...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668142/left-atrial-phasic-function-and-its-association-with-atrial-fibrillation-in-patients-after-transcatheter-aortic-valve-implantation
#18
Frédéric Poulin, Paaladinesh Thavendiranathan, Shemy Carasso, Harry Rakowski, Eric M Horlick, Mark D Osten, Robert J Cusimano, Anna Woo
BACKGROUND: Left atrial (LA) size is a marker of prognosis in severe aortic stenosis (AS). The aims of this retrospective study were to assess the impact of transcatheter aortic valve implantation (TAVI) on the recovery of LA phasic function and to assess the relationship between LA function and new-onset atrial fibrillation (NAF) after TAVI. METHODS: In this retrospective cohort study, LA function was measured using biplane volumes and 2-dimensional (2D) speckle tracking echocardiography (STE) in 52 patients (median age, 81 years) with severe AS before TAVI and at midterm follow-up...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668141/high-sensitivity-cardiac-troponin-risk-cutoffs-for-acute-cardiac-outcomes-at-emergency-department-presentation
#19
Peter A Kavsak, Andrew Worster, Jinhui Ma, Colleen Shortt, Natasha Clayton, Jonathan Sherbino, Stephen A Hill, Matthew McQueen, Shamir R Mehta, Philip J Devereaux
The optimal high-sensitivity cardiac troponin (hs-cTn) cutoffs for determining risk in patients who present with acute coronary syndrome symptoms are unknown. In 1137 emergency department patients we calculated adjusted relative risks for a composite outcome (myocardial infarction, unstable angina, heart failure, ventricular arrhythmia, or cardiovascular death) within 7 days for the presentation of hs-cTnT (Roche) and hs-cTnI (Abbott) assay concentrations on the basis of literature cutoffs. Patients with hs-cTn concentrations ≥ 14 ng/L had an adjusted relative risk of 4...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668140/clinical-features-diagnosis-and-management-of-patients-with-anderson-fabry-cardiomyopathy
#20
REVIEW
Haran Yogasundaram, Daniel Kim, Omar Oudit, Richard B Thompson, Frank Weidemann, Gavin Y Oudit
Anderson-Fabry disease (AFD) is an X-linked recessive, multisystem disease of lysosomal storage. A mutation in the gene encoding the hydrolase enzyme α-galactosidase A results in its deficiency, or complete absence of activity. Subsequent progressive intracellular accumulation of glycosphingolipids, predominantly globotriaosylceramide, in various tissues, results in progressive organ dysfunction and failure, most commonly affecting the kidneys, nervous system, skin, eyes, vascular endothelium, and the heart...
July 2017: Canadian Journal of Cardiology
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