journal
MENU ▼
Read by QxMD icon Read
search

International Journal of Hyperthermia

journal
https://www.readbyqxmd.com/read/28100096/targeting-therapy-resistant-cancer-stem-cells-by-hyperthermia
#1
A L Oei, L E M Vriend, P M Krawczyk, M R Horsman, N A P Franken, J Crezee
Eradication of all malignant cells is the ultimate but challenging goal of anti-cancer treatment; most traditional clinically-available approaches fail because there are cells in a tumor that either escape therapy or become therapy-resistant. A subpopulation of cancer cells, the cancer stem cells (CSCs), is considered to be of particular significance for tumor initiation, progression and metastasis. CSCs are considered in particular to be therapy-resistant and may drive disease recurrence, which positions CSCs in the focus of anti-cancer research, but successful CSC-targeting therapies are limited...
January 19, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28100078/percutaneous-microwave-ablation-mwa-increased-the-serum-levels-of-vegf-and-mmp-9-in-stage-i-non-small-cell-lung-cancer-nsclc
#2
Yang Ni, Xin Ye, Chao Wan, Qing Ni, Xia Yang, Guanghui Huang, Wenhong Li, Jiao Wang, Xiaoying Han, Zhigang Wei, Min Meng
BACKGROUND: Lung cancer is the leading cause of cancer death around the world. Percutaneous microwave ablation (MWA) is an emerging treatment strategy for medically inoperable early stage non-small cell lung cancer (NSCLC). In this study, we investigated the association of MWA and serum angiogensis promoters VEGF and MMP-9 in these patients subgroup. METHODS: We enrolled 52 patients with stage I NSCLC patients in this study. For each patient, blood samples were drawn by venous puncture, one immediately prior to MWA and the others on post-procedure days (PPD) 1, 3, 5, 7, 10 and 14...
January 18, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28093005/cardiac-and-respiratory-effects-of-deep-regional-hyperthermia-using-an-8-mhz-radiofrequency-capacitive-device-on-patients-with-cancer
#3
Rieko Izukura, Hajime Imada, Nobuko Hashiguchi, Hiroyuki Sawatari, Takayuki Ohguri, Mami Miyazono, Shin Ohta, Chizuko Takakura, Keiko Yamasaki, Chie Magota, Kanae Fujita, Hiromi Kuroda, Hideki Hirata, Tomoko Ohkusa, Akiko Chishaki
PURPOSE: Hyperthermia (HT), an adjuvant therapy for variable cancers, may cause physiological changes in the patients, which may lead to cardiovascular problems. Among various HT treatments, the physiological effects of deep regional HT are still unclear. We examined the physiological alterations throughout deep regional HT to improve the HT safety. MATERIALS AND METHODS: Thirty-one patients (age: 61±12 years) with cancer received HT in the thoracic or upper abdominal regions using an 8-MHz radiofrequency-capacitive-device for 50 min...
January 16, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28092994/current-status-and-future-prospects-of-hyperthermic-intraoperative-intraperitoneal-chemotherapy-hipec-clinical-trials-in-ovarian-cancer
#4
Renee A Cowan, Roisin E O'Cearbhaill, Oliver Zivanovic, Dennis S Chi
The natural history of advanced-stage epithelial ovarian cancer is one of clinical remission after surgery and platinum/taxane-based intravenous and/or intraperitoneal chemotherapy followed by early or late recurrence in the majority of patients. Prevention of progression and recurrence remains a major hurdle in the management of ovarian cancer. Recently, many investigators have evaluated the use of normothermic and hyperthermic intraoperative intraperitoneal drug delivery as a management strategy. This is a narrative review of the current status of clinical trials of hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) in ovarian cancer and the future directions for this treatment strategy...
January 16, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28081645/factors-related-to-recurrence-of-the-benign-non-functioning-thyroid-nodules-after-percutaneous-microwave-ablation
#5
Bei Wang, Zhi-Yu Han, Jie Yu, Zhigang -Cheng, Fangyi Liu, Xiao-Ling Yu, Chaonan Chen, Ju Liu, Ping Liang
PURPOSE: To determine the factors affecting the recurrence of the solitary benign thyroid nodules (BTN) after microwave ablation (MWA). MATERIALS AND METHODS: Between January 2013 and January 2015, a total of 110 patients with at least one solid thyroid nodule (solid component ≥ 80%) were enrolled. MWA was performed under continuous ultrasound (US) guidance. Before and during the follow-up, the thyroid nodule volume, thyroid function and cosmetic complaints were evaluated...
January 12, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28064557/compact-self-grounded-bow-tie-antenna-design-for-an-uwb-phased-array-hyperthermia-applicator
#6
Pegah Takook, Mikael Persson, Johanna Gellermann, Hana Dobšíček Trefná
Using UWB hyperthermia systems has the potential to improve the heat delivery to deep seated tumours. In this paper, we present a novel self-grounded Bow-Tie antenna design which is to serve as the basis element in a phased-array applicator. The UWB operation in the frequency range of 0.43-1 GHz is achieved by immersing the antenna in a water bolus. The radiation characteristics are improved by appropriate shaping the water bolus and by inclusion of dielectric layers on the top of the radiating arms of the antenna...
January 8, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28049386/quality-assurance-guidelines-for-superficial-hyperthermia-clinical-trials-i-clinical-requirements
#7
Hana Dobsicek Trefna, Hans Crezee, Manfred Schmidt Diplom-Physiker, Dietmar Marder, Ulf Lamprecht, Michael Ehmann, Josefin Hartmann, Jacek Nadobny, Johanna Gellermann, Netteke van Holthe, Pirus Ghadjar, Nicoletta Lomax, Sultan Abdel-Rahman, Christoph Bert, Akke Bakker, Mark Hurwitz, Chris J Diederich, Paul R Stauffer, Gerard C van Rhoon
Quality assurance guidelines are essential to provide uniform execution of clinical trials and treatment in the application of hyperthermia. This document provides definitions for a good hyperthermia treatment and identifies the clinical conditions where a certain hyperthermia system can or cannot adequately heat the tumor volume. It also provides brief description of the characteristics and performance of the current electromagnetic (radiative and capacitive), ultrasound and infrared heating techniques. This information helps to select the appropriate heating technique for the specific tumor location and size, and appropriate settings of the water bolus and thermometry...
January 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28049374/needle-track-seeding-after-percutaneous-radiofrequency-ablation-of-hepatocellular-carcinoma-14-year-experience-at-a-single-center
#8
Zhong-Yi Zhang, Wei Yang, Kun Yan, Ying Dai, Wei Wu, Jung-Chieh Lee, Min-Hua Chen
PURPOSE: To determine the incidence, risk factors and prognosis associated with needle track seeding after percutaneous radiofrequency ablations(RFA) for hepatocellular carcinoma(HCC) with a long-term follow-up. MATERIALS AND METHODS: 741 HCC patients undergoing percutaneous RFA were retrospectively analyzed. Mean follow-up interval was 34.3±26.8 months. All seeding neoplasms were diagnosed by imaging modalities with or without pathological evaluation. Risk factors, including Child-Pugh grading, tumor size, number, location, serum AFP level, track number, biopsy before RFA and electrode type were performed by univariate analysis...
January 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28044471/percutaneous-thermal-ablation-for-the-treatment-of-colorectal-liver-metastases-and-hepatocellular-carcinoma-a-comparison-of-local-therapeutic-efficacy
#9
Ming Liu, Guang-Liang Huang, Ming Xu, Fu-Shun Pan, Ming-de Lu, Ke-Guo Zheng, Ming Kuang, Xiao-Yan Xie
AIM: This study aimed to compare the local therapeutic efficacy of percutaneous thermal ablation for colorectal liver metastases (CRLM) and hepatocellular carcinoma (HCC). METHODS: One hundred sixty-one CRLM nodules in 101 patients and 122 HCC nodules in 97 patients were treated with thermal ablation. Complications and local efficacy were retrospectively compared. RESULTS: Major complications were observed in 2 (2.0%) patients in the CRLM group and 1 (1...
January 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28044461/equivalence-of-cell-survival-data-for-radiation-dose-and-thermal-dose-in-ablative-treatments-analysis-applied-to-essential-tremor-thalamotomy-by-focused-ultrasound-and-gamma-knife
#10
D Schlesinger, M Lee, G Ter Haar, B Sela, M Eames, J Snell, N Kassell, J Sheehan, J Larner, J-F Aubry
Thermal dose and absorbed radiation dose have historically been difficult to compare because different biological mechanisms are at work. Thermal dose denatures proteins and the radiation dose causes DNA damage in order to achieve ablation. The purpose of this paper is to use the proportion of cell survival as a potential common unit by which to measure the biological effect of each procedure. Survival curves for both thermal and radiation doses have been extracted from previously published data for three different cell types...
January 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27829290/hsp90-inhibitors-in-the-context-of-heat-shock-and-the-unfolded-protein-response-effects-on-a-primary-canine-pulmonary-adenocarcinoma-cell-line
#11
Arin N Graner, Justin E Hellwinkel, Alex M Lencioni, Helen J Madsen, Tessa A Harland, Paul Marchando, Ger J Nguyen, Mary Wang, Laura M Russell, Lynne T Bemis, Thomas J Anchordoquy, Michael W Graner
BACKGROUND: Agents targeting HSP90 and GRP94 are seldom tested in stressed contexts such as heat shock (HS) or the unfolded protein response (UPR). Tumor stress often activates HSPs and the UPR as pro-survival mechanisms. This begs the question of stress effects on chemotherapeutic efficacy, particularly with drugs targeting chaperones such as HSP90 or GRP94. We tested the utility of several HSP90 inhibitors, including PU-H71 (targeting GRP94), on a primary canine lung cancer line under HS/UPR stress compared to control conditions...
December 20, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27701920/status-and-advancement-of-microwave-ablation-in-china
#12
Jie Yu, Ping Liang
Tumour ablation is defined as the direct application of chemical or thermal therapy to eradicate or substantially destroy a tumour. Currently, minimally invasive ablation techniques are available for the local destruction of focal tumours in multiple organ sites. Microwave ablation (MWA) is premised on the biological response of solid tumours to tissue hyperthermia, and it is a relatively low-risk procedure. Due to several advantages of MWA, including higher thermal efficiency, higher capability for coagulating blood vessels, faster ablation time and the simultaneous application of multiple antennae, MWA could be a promising minimally invasive ablation technique for the treatment of solid tumours...
December 20, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27978776/short-course-preoperative-radiotherapy-combined-with-chemotherapy-delayed-surgery-and-local-hyperthermia-for-rectal-cancer-a-phase-ii-study
#13
A O Rasulov, S S Gordeyev, Yu A Barsukov, S I Tkachev, A G Malikhov, S S Balyasnikova, M Yu Fedyanin
PURPOSE: The aim of this study was to investigate the feasibility of short-course radiotherapy with oral capecitabine, hyperthermia and delayed surgery for neoadjuvant treatment of rectal cancer. METHODS: Patients with clinically staged T2-3N0-2M0 primary rectal cancer were included. All patients received short-course 25 Gy in 5 Gy fractions radiotherapy with capecitabine, local hyperthermia and metronidazole. Capecitabine 1000 mg/m2 twice a day was given on days 1-14...
December 15, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27903081/percutaneous-microwave-ablation-of-renal-cell-carcinoma-is-safe-in-patients-with-renal-dysfunction
#14
Yan Lin, Ping Liang, Xiao-Ling Yu, Jie Yu, Zhi-Gang Cheng, Zhi-Yu Han, Fangyi Liu
OBJECTIVES: To present the clinical effect of microwave ablation (MWA) on renal cell carcinoma (RCC) of the patients with renal dysfunction, mainly focussing on the extent of renal tumour control and damage to the residual kidney function. METHODS AND MATERIALS: From 2006 to 2014, 19 tumours of 18 patients with renal dysfunction underwent percutaneous ultrasound-guided MWA in our institution. The tumour diameters range from 1.9 to 5.0 cm. The serum creatinine and urea levels of each patient pre-MWA, one day after MWA and the most recent occasion on record at our institution were collected...
December 15, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27855557/201-consecutive-cytoreductive-surgery-crs-and-hyperthermic-intraperitoneal-chemotherapy-hipec-procedures-in-a-single-asian-tertiary-centre
#15
Grace Tan, Claramae Chia, Mrinal Kumar, Su Pin Choo, John Chia, Chee Kian Tham, Clarinda Chua, Khee Chee Soo, Melissa Teo
INTRODUCTION: Peritoneal carcinomatosis (PC) is increasingly being treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). We provide a review of a high-volume Asian institute's experience and survival outcomes with this procedure. METHODS: Data were prospectively collected from 201 consecutive CRS and HIPEC procedures performed in a single institution between April 2001 and November 2015. Our primary endpoints were overall survival (OS) and disease-free survival (DFS), and secondary endpoints were morbidity and mortality...
December 14, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27951733/a-comparison-of-the-heating-characteristics-of-capacitive-and-radiative-superficial-hyperthermia
#16
H P Kok, J Crezee
BACKGROUND: Superficial hyperthermia is applied in combination with radiotherapy for e.g. melanoma and recurrent breast cancer, using both capacitive and radiative systems. In this paper numerical simulations are applied to address the question which technique yields the most favorable heating characteristics. METHODS: A 434MHz contact flexible microstrip applicator (CFMA type 4H, size 19.6 × 19.6cm(2)) and a capacitive system consisting of two circular electrodes with diameter 15 and 25cm were modelled...
December 12, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27817240/microwave-ablation-versus-hepatic-resection-for-the-treatment-of-hepatocellular-carcinoma-and-oesophageal-variceal-bleeding-in-cirrhotic-patients
#17
Qiang-Bo Zhang, Xiu-Guo Zhang, Run-de Jiang, Chun-Xiao Hu, Dong Sun, Lin Ran, Zong-Li Zhang
PURPOSE: The aim of this study was to compare the results of microwave ablation (MWA) and hepatic resection (HR) when combined with pericardial devascularisation plus splenectomy (PCDV) for the treatment of patients with cirrhosis complicated by small hepatocellular carcinoma (HCC) and oesophageal variceal bleeding (EVB). MATERIALS AND METHODS: Between 2001 and 2013, 73 patients (median age 53.2 years, 67% male) with small HCC and concomitant EVB who underwent MWA or HR for HCC and PCDV for cirrhotic portal hypertension were selected retrospectively for inclusion in this study...
December 8, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27829293/incorporating-detailed-biology-in-hyperthermia-treatment-planning-a-necessary-condition-for-progress
#18
Robert J Myerson
No abstract text is available yet for this article.
December 7, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27724046/combination-therapy-of-three-dimensional-3d-visualisation-operative-treatment-planning-system-and-us-guided-percutaneous-microwave-ablation-in-larger-renal-cell-carcinomas-d%C3%A2-%C3%A2-%C3%A2-4%C3%A2-cm-preliminary-results
#19
Xin Li, Jie Yu, Ping Liang, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Hui Huang, Shaobo Duan, Jiasheng Zheng
PURPOSE: To analyse the clinical outcomes of combination therapy of three-dimensional (3D) visualisation operative treatment planning system and US-guided percutaneous microwave ablation (PMWA) in larger renal cell carcinomas (RCCs) (D ≥ 4 cm). MATERIALS AND METHODS: The results from 20 patients with 20 larger RCCs treated with a 3D visualisation operative treatment planning system and US-guided PMWA were reviewed retrospectively. The patients were followed up by contrast-enhanced images at 1, 3, and 6 months and every 6 months thereafter...
December 7, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27868461/a-new-approach-to-feedback-control-of-radiofrequency-ablation-systems-for-large-coagulation-zones
#20
Bing Zhang, Michael A J Moser, Edwin M Zhang, Yigang Luo, Wenjun Zhang
AIM: The aim of this study was to investigate the feasibility of achieving relatively large coagulation zones (i.e. ≥3 cm in diameter) with radiofrequency ablation (RFA) by using a broad control system. MATERIALS AND METHODS: A broad control system consists of information such as (i) the area of the tumour tissue for feedback control, (ii) the set-point temperature and (iii) the control law. The proposed approach has advanced knowledge in (i) and (ii) in particular...
December 6, 2016: International Journal of Hyperthermia
journal
journal
29125
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"