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Diabetes Research and Clinical Practice

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https://www.readbyqxmd.com/read/28214668/diabetes-and-disability-in-older-australians-the-australian-diabetes-obesity-and-lifestyle-ausdiab-study
#1
Digsu N Koye, Jonathan E Shaw, Dianna J Magliano
AIMS: To examine the association between diabetes and disability in older Australians and to identify factors that explain this association. METHODS: We analysed data from a subsample of the Australian Diabetes, Obesity and Lifestyle study (AusDiab) cohort. Disability was measured using the Katz questionnaire in those aged 60years or over and was defined as some difficulty in any of the Katz activities of daily living (ADL) questions. RESULTS: Among 2373 study participants aged 60years or above who had a disability assessment at the third wave of follow-up (2011-12), 255 (11%) reported at least some disability...
February 7, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28214669/correlates-of-overweight-and-obesity-in-5529-adolescents-with-type-1-diabetes-the-t1d-exchange-clinic-registry
#2
Karl E Minges, Robin Whittemore, Stuart A Weinzimer, Melinda L Irwin, Nancy S Redeker, Margaret Grey
AIMS: To describe the prevalence of overweight and obesity in adolescents with type 1 diabetes (T1D) and to examine the associations among socio-demographic, clinical, and self-management factors by weight status. METHODS: We analyzed baseline data obtained from 5529 adolescents with T1D (mean age=15.4±1.4years, 51.8% male, 77.9% white, mean HbA1c=8.7±1.8%; 72mmol/mol) from the T1D Exchange Clinic Registry. We examined correlates of weight status using multinomial logistic regression analyses...
February 4, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28189950/the-impact-of-travel-distance-travel-time-and-waiting-time-on-health-related-quality-of-life-of-diabetes-patients-an-investigation-in-six-european-countries
#3
Uwe Konerding, Tom Bowen, Sylvia G Elkhuizen, Raquel Faubel, Paul Forte, Eleftheria Karampli, Mahdi Mahdavi, Tomi Malmström, Elpida Pavi, Paulus Torkki
AIMS: The effects of travel distance and travel time to the primary diabetes care provider and waiting time in the practice on health-related quality of life (HRQoL) of patients with type 2 diabetes are investigated. RESEARCH DESIGN AND METHODS: Survey data of 1313 persons with type 2 diabetes from six regions in England (274), Finland (163), Germany (254), Greece (165), the Netherlands (354), and Spain (103) were analyzed. Various multiple linear regression analyses with four different EQ-5D-3L indices (English, German, Dutch and Spanish index) as target variables, with travel distance, travel time, and waiting time in the practice as focal predictors and with control for study region, patient's gender, patient's age, patient's education, time since diagnosis, thoroughness of provider-patient communication were computed...
February 2, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28189949/attitude-complications-ability-of-fasting-and-glycemic-control-in-fasting-ramadan-by-children-and-adolescents-with-type-1-diabetes-mellitus
#4
Asma Deeb, Nabras Al Qahtani, Mariette Akle, Himanshi Singh, Rifah Assadi, Salima Attia, Hana Al Suwaidi, Tara Hussain, Nico Naglekerke
OBJECTIVES: Sick individuals and children are exempted from fasting Ramadan. Fasting by type 1 diabetes patients might predispose to acute complications. There are no guidelines on fasting safety or its impact on diabetes control in children and adolescents. We aim to assess patients' attitude towards fasting, frequency of complications and impact on glycemic control in children with type 1 diabetes. RESEARCH DESIGN & METHODS: 65 children with type 1 diabetes were enrolled...
February 1, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28190528/criterion-used-for-determination-of-test-cut-off-value
#5
LETTER
Farrokh Habibzadeh, Parham Habibzadeh, Mahboobeh Yadollahie
No abstract text is available yet for this article.
January 30, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28209549/factors-affecting-consultation-length-in-a-japanese-diabetes-practice
#6
Yusuke Kabeya, Junko Uchida, Masao Toyoda, Takeshi Katsuki, Yoichi Oikawa, Kiyoe Kato, Toshihide Kawai, Akira Shimada, Yoshihito Atsumi, Megumu Higaki
AIMS: Sufficient consultation time is important for establishing good doctor-patient relationship. We examined the factors that affect consultation length in Japanese diabetes practice. METHODS: This was a cross-sectional study performed at a diabetes clinic in central Tokyo, Japan. Regular diabetes consultations of 1197 patients with 22 physicians were analyzed. Consultation time and clinical characteristics were obtained from the electronic records. A negative binomial model, which included patient and physician characteristics, was constructed to examine the association of the variables with consultation length...
January 29, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28189951/which-creatinine-based-estimated-glomerular-filtration-rate-equation-best-predicts-all-cause-mortality-in-chinese-subjects-with-type-2-diabetes
#7
C H Lee, A Z L Shih, Y C Woo, C H Y Fong, M M A Yuen, W S Chow, K S L Lam
AIM: In Chinese, ethnicity-based and/or diabetes specific modifications of the Modification of Diet in Renal Disease (MDRD) and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations have been developed for determining estimated glomerular filtrate rate (eGFR). This study aimed to compare the performance of five different creatinine-based eGFR equations in predicting all-cause mortality among Chinese subjects with type 2 diabetes (T2DM). METHODS: A total of 6739 Chinese subjects with T2DM were included...
January 29, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28189948/considerations-for-management-of-patients-with-diabetic-macular-edema-optimizing-treatment-outcomes-and-minimizing-safety-concerns-through-interdisciplinary-collaboration
#8
REVIEW
W David Strain, Xavier Cos, Christian Prünte
Diabetes is a growing worldwide epidemic and a leading cause of blindness in working-age people around the world. Diabetic retinopathy (DR) and diabetic macular edema (DME) are common causes of visual impairment in people with diabetes and often indicate the presence of diabetes-associated preclinical micro- and macrovascular complications. As such, patients with DR and DME often display complex, highly comorbid profiles. Several treatments are currently available for the treatment of DME, including anti-vascular endothelial growth factor (VEGF) agents, which are administered via intravitreal injection...
January 29, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28192721/trend-projection-and-appropriate-body-mass-index-cut-off-point-for-diabetes-and-hypertension-in-bangladesh
#9
Md Mizanur Rahman, Shamima Akter, Jenny Jung, Md Shafiur Rahman, Papia Sultana
BACKGROUND: Rapid increasing of high body mass index (BMI) is a global health concern. Population with high BMI predicts an increased risk of diabetes and hypertension. The objective of the present study is to estimate the trend and prediction of diabetes and hypertension in Bangladesh, to examine the association of BMI with risk of diabetes and hypertension, and to ascertain an appropriate BMI cut-off point for screening diabetes. METHODS: We searched PubMed from inception to August 2016 and identified studies reporting diabetes and hypertension prevalence in Bangladesh...
January 23, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28167324/re-organizing-inpatient-care-saves-legs-in-patients-with-diabetic-foot-infections
#10
Miska Laakso, Mikael Honkasalo, Juha Kiiski, Meri Ala-Houhala, Heidi Haapasalo, Heikki-Jussi Laine, Tiina Luukkaala, Jorma Lahtela, Ilkka Kaartinen
AIMS: In this study, we evaluated the effects of the re-organization of inpatient care for patients with a diabetic foot infection, and the implementation of a specialized multi-disciplinary wound department at an academic tertiary hospital. METHODS: This was a retrospective cohort study, comprising 272 patients treated for diabetic foot infections in 2006-2007 (Group 1, n=124) and 2013-2014 (Group 2, n=148). In 2012, inpatient care of all chronic wounds was centralized at a single wound department with a multi-disciplinary team...
January 22, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28131070/health-education-on-diabetes-and-other-non-communicable-diseases-imparted-to-teachers-shows-a-cascading-effect-a-study-from-southern-india
#11
Sundaram Selvam, Narayanasamy Murugesan, Chamukuttan Snehalatha, Arun Nanditha, Arun Raghavan, Mary Simon, Priscilla Susairaj, Ambady Ramachandran
AIMS: The aims were to assess effect of a short training programme on non-communicable diseases (NCDs), particularly diabetes on school teachers and also on students who were in turn educated by them. Lifestyle changes made by both groups were assessed 6months later. METHODS: Graduate teachers (n=1017) from 2 districts in Tamilnadu, India were trained using audio visual aids in batches of 100, on healthy lifestyle practices, prevention and management of diabetes...
January 17, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28131069/oral-candidal-speciation-virulence-and-antifungal-susceptibility-in-type-2-diabetes-mellitus
#12
Pratik N Patel, Parul Sah, Chetana Chandrashekar, Sudha Vidyasagar, J Venkata Rao, Mradul Tiwari, Raghu Radhakrishnan
OBJECTIVES: To determine the oral candidal carriage (OCC), activity of virulent factors and fluconazole susceptibility in subjects with type 2 diabetes mellitus (T2DM) and investigate their association with HbA1c measurements. MATERIALS AND METHODS: A cross sectional study was conducted on 100 diabetics and 100 healthy volunteers. The virulence was assessed by measuring the phospholipase activity and proteolysis index. Fluconazole susceptibility was performed using the gradient diffusion method...
January 17, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28129564/prevalence-of-high-hba1c-levels-in-brazilian-adolescents-the-study-of-cardiovascular-risk-in-adolescents
#13
Rita de Cássia Lima Fernandes, Gabriela H Teló, Felipe V Cureau, Laura A Barufaldi, Maria Cristina C Kuschnir, Beatriz D Schaan, Moyses Szklo, Katia V Bloch
AIM: To evaluate the prevalence of elevated glycated haemoglobin (HbA1c) levels in a population of adolescents participating in the Study of Cardiovascular Risk in Adolescents. METHODS: This is a school-based cross-sectional study based on a complex sample of adolescents 12-17years old representative at the national and macro-regional levels and for each Brazilian state capital. Blood was collected in schools and then evaluated in a single laboratory. HbA1c levels were considered elevated if ⩾5...
January 16, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28110238/pre-pregnancy-weight-change-and-incidence-of-gestational-diabetes-mellitus-a-finding-from-a-prospective-cohort-study
#14
Akilew Awoke Adane, Leigh R Tooth, Gita D Mishra
AIMS: In a population-based cohort study we examined the associations between early adult pre-pregnancy weight change and the risk of gestational diabetes mellitus (GDM). METHODS: The study included 3111 women from the 1973-78 cohort of the Australian Longitudinal Study on Women's Health. These women have been surveyed regularly since 1996. Women without diabetes and GDM were followed-up between 2003 and 2012. Generalized estimating equations were used to assess the effect of baseline (1996, mean age 20years) and pre-pregnancy body mass index (BMI) and the pre-pregnancy weight changes on the incidence of GDM...
January 11, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28081450/heparanase-driven-inflammation-from-the-ages-stimulated-macrophages-changes-the-functions-of-glomerular-endothelial-cells
#15
Guang Xu, Qiaojing Qin, Min Yang, Zhongdong Qiao, Yong Gu, Jianying Niu
AIMS: Amounts of macrophages were infiltrated in glomeruli in diabetic nephropathy. Heparanase has been thought to be closely related to proteinuria. Our aims were to determine the effect of heparanase on the inflammation in AGEs-stimulated macrophages and its role on the functions of glomerular endothelial cells (GEnCs). METHODS: The expression of inflammation cytokines in macrophages were assayed by q-RT PCR, western, and ELISA. Then western was used to measure the expression of RAGE and key proteins in NF-κB pathway in macrophages...
December 30, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28110239/relationship-between-hla-haplotype-and-bmi-change-in-japanese-slowly-progressive-type-1-diabetes-patients
#16
Sari Hoshina, Junnosuke Miura, Yasuko Uchigata
We investigated the association between susceptible HLA and BMI change rate from diagnosis of diabetes to diagnosis of slowly progressive type 1 diabetes in Japanese diabetic patients. Subjects with the HLA DRB1*04:05-DQB1*04:01 haplotype were more likely to show weight loss than those without. This HLA haplotype might affect weight loss.
December 28, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28167326/association-of-grade-of-non-alcoholic-fatty-liver-disease-and-glycated-albumin-to-glycated-hemoglobin-ratio-in-patients-with-type-2-diabetes-mellitus
#17
Chan-Hee Jung, Bora Lee, Dug-Hyun Choi, Sang-Hee Jung, Bo-Yeon Kim, Chul-Hee Kim, Sung-Koo Kang, Ji-Oh Mok
AIMS: The aim of this study was to investigate the association between the glycated albumin (GA) to glycated hemoglobin (HbA1c) (GA/HbA1c) ratio and grade of non-alcoholic fatty liver disease (NAFLD) on ultrasonography (US) in patients with type 2 diabetes mellitus (T2DM). METHODS: This retrospective, cross-sectional study was performed with data obtained from 186 T2DM patients. Participants were assessed for serum GA/HbA1c ratio and fatty liver using US. NAFLD was defined as ultrasonographically detected fatty liver and was graded as normal, mild, moderate, and severe fatty liver...
December 27, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28119195/sleep-duration-and-smoking-are-associated-with-coronary-heart-disease-among-us-adults-with-type-2-diabetes-gender-differences
#18
Lixin Li, Shaoqing Gong, Chun Xu, Joseph Yi Zhou, Ke-Sheng Wang
AIMS: The associations of moderate alcohol consumption, sleep duration, and tobacco smoking with coronary heart disease (CHD) among patients with type 2 diabetes mellitus (T2D) are not clearly clarified. The aims of the study were to evaluate the associations of lifestyle factors, hypertension, obesity, depression and sleep duration with CHD development among patients with T2D, and particularly, to examine the gender differences in risk factors for CHD. METHODS: A total of 2335 T2D adults were selected from the 2012 National Health Interview Survey...
December 27, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28086201/the-effects-of-glp-1-based-therapies-on-postprandial-haemodynamics-two-randomised-placebo-controlled-trials-in-overweight-type-2-diabetes-patients
#19
Mark M Smits, Lennart Tonneijck, Marcel H A Muskiet, Trynke Hoekstra, Mark H H Kramer, Michaela Diamant, Daniël H van Raalte
AIMS: To assess the effects of glucagon-like peptide (GLP)-1 receptor agonists and dipeptidyl peptidase (DPP)-4 inhibitors on postprandial haemodynamics. METHODS: 57 patients with type 2 diabetes (mean±SD age 62.8±6.9years; BMI 31.8±4.1kg/m(2); HbA1c 7.3±0.6%) were included in an acute (exenatide- or placebo-infusion) and 12-week (liraglutide, sitagliptin or placebo) randomised, placebo-controlled, double-blind trial. Systemic haemodynamics (oscillometric technique and finger photoplethysmography), vascular stiffness (tonometry), and sympathetic nervous system (SNS)-activity (heart rate variability) were determined in the fasting state and following a standardised mixed meal...
December 27, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28081449/diabetes-diagnostic-thresholds-of-the-glycated-hemoglobin-a1c-and-fasting-plasma-glucose-levels-considering-the-5-year-incidence-of-retinopathy
#20
Tomoko Nakagami, Kanako Takahashi, Chikako Suto, Junko Oya, Yuki Tanaka, Moritoshi Kurita, Chisato Isago, Yukiko Hasegawa, Arata Ito, Yasuko Uchigata
AIMS: As retinopathy is used as a defining threshold of diabetes, we assessed the glycated hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) values associated with an increased risk of 5-year incidence of retinopathy. METHODS: We studied HbA1c, FPG, and optic fundus findings of 2605 individuals without previously diagnosed diabetes annually during a 5-year period. Retinopathy was examined using non-mydriatic, 45° digital fundus photography. Baseline levels were stratified as <5...
December 27, 2016: Diabetes Research and Clinical Practice
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