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European Journal of Epidemiology

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https://www.readbyqxmd.com/read/28434075/associations-of-self-reported-smoking-cotinine-levels-and-epigenetic-smoking-indicators-with-oxidative-stress-among-older-adults-a-population-based-study
#1
Xu Gao, Xīn Gào, Yan Zhang, Lutz Philipp Breitling, Ben Schöttker, Hermann Brenner
Tobacco smoking and oxidative stress (OS) are both related to a wide spectrum of adverse age-related health outcomes, but their association is not yet well-established. We examined the associations of self-reported smoking indicators, serum cotinine levels and smoking-related DNA methylation biomarkers with two urinary proxy markers of OS, 8-isoprostane (8-iso) and 8-hydroxy-2'-deoxyguanosine (8-oxodG), in two independent subsets of older adults recruited in Germany (discovery set: n = 978, validation set: n = 531)...
April 22, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28417273/maternal-height-and-breast-cancer-risk-results-from-a-study-nested-within-the-epic-greece-cohort
#2
LETTER
Michail Katsoulis, Carlo La Vecchia, Antonia Trichopoulou, Pagona Lagiou
The positive association of adult height with breast cancer (BC) risk has been hypothesized to be partly accounted for by an association of this risk with maternal height (operating in utero to modify hormone effects). In a case-control study (271 BC patients and 791 controls) nested within the EPIC-Greece cohort, we applied mediation analysis to calculate the direct and indirect (through the woman's own height) effect of maternal height on BC risk. Per 5 cm increase in maternal height and depending on its reference value: the indirect effect odds ratio ranges from 1...
April 17, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28409278/moderate-alcohol-consumption-is-associated-with-lower-chronic-disease-burden-expressed-in-disability-adjusted-life-years-a-prospective-cohort-study
#3
Joline W J Beulens, Heidi P Fransen, Ellen A Struijk, Jolanda M A Boer, G Ardine de Wit, N Charlotte Onland-Moret, Jeljer Hoekstra, H Bas Bueno-de-Mesquita, Petra H M Peeters, Anne M May
The relation of alcohol consumption with disease burden remains debated partly due to opposite associations with cardiovascular disease (CVD) and cancer. The relation of alcohol consumption with disease burden expressed in disability-adjusted life years (DALYs) summarizes opposing associations of alcohol consumption on chronic diseases. This study aimed to investigate the association of alcohol consumption with chronic disease burden expressed in DALYs based on individual-participant data. The study was a prospective study among 33,066 men and women from the EPIC-NL cohort...
April 13, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28405867/low-serum-magnesium-levels-are-associated-with-increased-risk-of-fractures-a-long-term-prospective-cohort-study
#4
Setor Kwadzo Kunutsor, Michael Richard Whitehouse, Ashley William Blom, Jari Antero Laukkanen
Magnesium, which is an essential trace element that plays a key role in several cellular processes, is a major component of bone; however, its relationship with risk of major bone fractures is uncertain. We aimed to investigate the association of baseline serum magnesium concentrations with risk of incident fractures. We analyzed data on 2245 men aged 42-61 years in the Kuopio Ischemic Heart Disease prospective cohort study, with the assessment of serum magnesium measurements and dietary intakes made at baseline...
April 12, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28397016/food-groups-and-risk-of-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-prospective-studies
#5
Lukas Schwingshackl, Georg Hoffmann, Anna-Maria Lampousi, Sven Knüppel, Khalid Iqbal, Carolina Schwedhelm, Angela Bechthold, Sabrina Schlesinger, Heiner Boeing
The aim of this systematic review and meta-analysis was to synthesize the knowledge about the relation between intake of 12 major food groups and risk of type 2 diabetes (T2D). We conducted a systematic search in PubMed, Embase, Medline (Ovid), Cochrane Central, and Google Scholar for prospective studies investigating the association between whole grains, refined grains, vegetables, fruits, nuts, legumes, eggs, dairy, fish, red meat, processed meat, and sugar-sweetened beverages (SSB) on risk of T2D. Summary relative risks were estimated using a random effects model by contrasting categories, and for linear and non-linear dose-response relationships...
April 10, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28391539/interactions-between-dietary-acrylamide-intake-and-genes-for-ovarian-cancer-risk
#6
Janneke G F Hogervorst, Piet A van den Brandt, Roger W L Godschalk, Frederik-Jan van Schooten, Leo J Schouten
Some epidemiological studies observed a positive association between dietary acrylamide intake and ovarian cancer risk but the causality needs to be substantiated. By analyzing gene-acrylamide interactions for ovarian cancer risk for the first time, we aimed to contribute to this. The prospective Netherlands Cohort Study on diet and cancer includes 62,573 women, aged 55-69 years. At baseline in 1986, a random subcohort of 2589 women was sampled from the total cohort for a case cohort analysis approach. Dietary acrylamide intake of subcohort members and ovarian cancer cases (n = 252, based on 20...
April 8, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28374228/milk-and-dairy-consumption-and-risk-of-cardiovascular-diseases-and-all-cause-mortality-dose-response-meta-analysis-of-prospective-cohort-studies
#7
Jing Guo, Arne Astrup, Julie A Lovegrove, Lieke Gijsbers, David I Givens, Sabita S Soedamah-Muthu
With a growing number of prospective cohort studies, an updated dose-response meta-analysis of milk and dairy products with all-cause mortality, coronary heart disease (CHD) or cardiovascular disease (CVD) have been conducted. PubMed, Embase and Scopus were searched for articles published up to September 2016. Random-effect meta-analyses with summarised dose-response data were performed for total (high-fat/low-fat) dairy, milk, fermented dairy, cheese and yogurt. Non-linear associations were investigated using the spine models and heterogeneity by subgroup analyses...
April 3, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28342085/concerns-about-the-long-term-safety-of-live-kidney-donors-are-justified
#8
Abimereki D Muzaale, Allan B Massie, Dorry L Segev
No abstract text is available yet for this article.
March 24, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28321694/the-born-in-guangzhou-cohort-study-bigcs
#9
Xiu Qiu, Jin-Hua Lu, Jian-Rong He, Kin-Bong Hubert Lam, Song-Ying Shen, Yong Guo, Ya-Shu Kuang, Ming-Yang Yuan, Lan Qiu, Nian-Nian Chen, Min-Shan Lu, Wei-Dong Li, Yan-Fei Xing, Feng-Juan Zhou, Suzanne Bartington, Kar Keung Cheng, Hui-Min Xia
The Born in Guangzhou Cohort Study (BIGCS) is a large-scale prospective observational study investigating the role of social, biological and environmental influences on pregnancy and child health and development in an urban setting in southern China. Pregnant women who reside in Guangzhou and who attend Guangzhou Women and Children's Medical Center (GWCMC) for antenatal care in early pregnancy (<20 weeks' gestation) are eligible for inclusion. Study recruitment commenced in February 2012, with an overall participation rate of 76...
March 20, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28314982/time-trends-of-cause-specific-mortality-among-resettlers-in-germany-1990-through-2009
#10
Simone Kaucher, Valentina Leier, Andreas Deckert, Bernd Holleczek, Christa Meisinger, Volker Winkler, Heiko Becher
Resettlers (in German: (Spät-)Aussiedler) form one of the biggest migrant groups in Germany. It is known that migrants have different mortality patterns compared to the autochthon population. In this paper, we combined data from three resettler cohorts and examined differences in mortality from non-communicable diseases among resettlers in Germany and the German population. Furthermore, we investigated time trends of cause-specific mortality for 20 years of follow-up and compared it with the German mortality rates...
March 17, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28314981/time-trends-in-incidence-rates-of-venous-thromboembolism-in-a-large-cohort-recruited-from-the-general-population
#11
Nadia Arshad, Trond Isaksen, John-Bjarne Hansen, Sigrid K Brækkan
Changes in the incidence of venous thromboembolism (VTE) during the last two decades have not been extensively studied. Therefore, we studied time trends in the incidence rates (IRs) of deep vein thrombosis (DVT) and pulmonary embolism (PE) in a cohort of 26,855 subjects, aged 25-97 years, enrolled in the Tromsø study in 1994/1995. The subject were followed-up throughout 2012, and all symptomatic, objectively confirmed, incident VTEs were identified using multiple sources (hospital discharge-, radiology procedure- and autopsy registry) and validated by review of medical records...
March 17, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28280950/transportation-noise-exposure-and-cardiovascular-mortality-a-nationwide-cohort-study-from-switzerland
#12
Harris Héritier, Danielle Vienneau, Maria Foraster, Ikenna Collins Eze, Emmanuel Schaffner, Laurie Thiesse, Franziska Rudzik, Manuel Habermacher, Micha Köpfli, Reto Pieren, Mark Brink, Christian Cajochen, Jean Marc Wunderli, Nicole Probst-Hensch, Martin Röösli
Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses on the association between cardiovascular mortality in Switzerland and the three major transportation noise sources-road, railway and aircraft traffic-along with a novel noise metric termed intermittency ratio (IR), expressing the percentage contribution of individual noise events to the total noise energy from all sources above background levels...
March 9, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28275904/on-progress-in-epidemiologic-academia
#13
Olli S Miettinen
Professor Hofman, in his capacity as the Editor-in-Chief of this journal of "epidemiology," invited me to write an essay for it, given that I've been immersed in epidemiologic academia for a good half-century already. He thought that I likely would have something noteworthy to say, based on my personal experience, about the evolution of "epidemiology" in those decades past, and perhaps also in decades yet to come. In this response to Hofman's invitation I naturally focus on my experience with the research-and-teaching (R & T) that are the core business of epidemiologic academia...
March 8, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28271174/advanced-paternal-age-and-stillbirth-rate-a-nationwide-register-based-cohort-study-of-944-031-pregnancies-in-denmark
#14
Stine Kjaer Urhoj, Per Kragh Andersen, Laust Hvas Mortensen, George Davey Smith, Anne-Marie Nybo Andersen
Advanced paternal age has been associated with a variety of rare conditions and diseases of great public health impact. An increased number of de novo point mutations in sperm with increasing age have been suggested as a mechanism, which would likely also affect fetal viability. We examined the association between paternal age and stillbirth rate in a large nationwide cohort. We identified all pregnancies in Denmark from 1994 to 2010 carried to a gestational age of at least 22 completed weeks (n = 944,031) as registered in national registers and linked to individual register data about the parents...
March 7, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28190139/longitudinal-and-postural-changes-of-blood-pressure-predict-dementia-the-malm%C3%A3-preventive-project
#15
Hannes Holm, Katarina Nägga, Erik D Nilsson, Olle Melander, Lennart Minthon, Erasmus Bachus, Artur Fedorowski, Martin Magnusson
The role of blood pressure (BP) changes in dementia is debatable. We aimed to analyse how resting and postural BP changes relate to incident dementia over a long-term follow-up. In the prospective population-based Malmö Preventive Project, 18,240 study participants (mean age: 45 ± 7 years, 63% male) were examined between 1974 and 1992 with resting and standing BP measurement, and re-examined between 2002 and 2006 at mean age of 68 ± 6 years with resting BP. A total of 428 participants (2.3%) were diagnosed with dementia through Dec 31, 2009...
February 11, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28185034/agricultural-activities-and-the-incidence-of-parkinson-s-disease-in-the-general-french-population
#16
Sofiane Kab, Johan Spinosi, Laura Chaperon, Aline Dugravot, Archana Singh-Manoux, Frédéric Moisan, Alexis Elbaz
Most studies on pesticides and Parkinson's disease (PD) focused on occupational exposure in farmers. Whether non-occupational exposure is associated with PD has been little explored. We investigated the association between agricultural characteristics and PD incidence in a French nationwide ecologic study. We hypothesized that persons living in regions with agricultural activities involving more intensive pesticide use would be at higher risk. We identified incident PD cases from French National Health Insurance databases (2010-2012)...
February 9, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28176141/myocardial-infarction-and-future-risk-of-cancer-in-the-general-population-the-troms%C3%A3-study
#17
Ludvig B Rinde, Birgit Småbrekke, Erin M Hald, Ellen E Brodin, Inger Njølstad, Ellisiv B Mathiesen, Maja-Lisa Løchen, Tom Wilsgaard, Sigrid K Brækkan, Anders Vik, John-Bjarne Hansen
The association between myocardial infarction (MI) and future risk of incident cancer is scarcely investigated. Therefore, we aimed to study the risk of cancer after a first time MI in a large cohort recruited from a general population. Participants in a large population-based study without a previous history of MI or cancer (n = 28,763) were included and followed from baseline to date of cancer, death, migration or study end. Crude incidence rates (IRs) and hazard ratios (HRs) for cancer after MI were calculated...
February 7, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28280949/on-the-potential-of-academic-epidemiology
#18
Sandro Galea
No abstract text is available yet for this article.
March 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28258521/the-modelled-impact-of-increases-in-physical-activity-the-effect-of%C3%A2-both-increased-survival-and-reduced-incidence-of-disease
#19
Oliver T Mytton, Marko Tainio, David Ogilvie, Jenna Panter, Linda Cobiac, James Woodcock
Physical activity can affect 'need' for healthcare both by reducing the incidence rate of some diseases and by increasing longevity (increasing the time lived at older ages when disease incidence is higher). However, it is common to consider only the first effect, which may overestimate any reduction in need for healthcare. We developed a hybrid micro-simulation lifetable model, which made allowance for both changes in longevity and risk of disease incidence, to estimate the effects of increases in physical activity (all adults meeting guidelines) on measures of healthcare need for diseases for which physical activity is protective...
March 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28258520/novel-inflammatory-markers-for-incident-pre-diabetes-and-type-2-diabetes-the-rotterdam-study
#20
Adela Brahimaj, Symen Ligthart, Mohsen Ghanbari, Mohammad Arfan Ikram, Albert Hofman, Oscar H Franco, Maryam Kavousi, Abbas Dehghan
The immune response involved in each phase of type 2 diabetes (T2D) development might be different. We aimed to identify novel inflammatory markers that predict progression from normoglycemia to pre-diabetes, incident T2D and insulin therapy. We used plasma levels of 26 inflammatory markers in 971 subjects from the Rotterdam Study. Among them 17 are novel and 9 previously studied. Cox regression models were built to perform survival analysis. MAIN OUTCOME MEASURES: During a follow-up of up to 14...
March 2017: European Journal of Epidemiology
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