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European Journal of Epidemiology

Sander Greenland
I present an overview of two methods controversies that are central to analysis and inference: That surrounding causal modeling as reflected in the "causal inference" movement, and that surrounding null bias in statistical methods as applied to causal questions. Human factors have expanded what might otherwise have been narrow technical discussions into broad philosophical debates. There seem to be misconceptions about the requirements and capabilities of formal methods, especially in notions that certain assumptions or models (such as potential-outcome models) are necessary or sufficient for valid inference...
February 20, 2017: European Journal of Epidemiology
Dagfinn Aune, Abhijit Sen, Sabrina Schlesinger, Teresa Norat, Imre Janszky, Pål Romundstad, Serena Tonstad, Elio Riboli, Lars J Vatten
Different adiposity measures have been associated with increased risk of atrial fibrillation, however, results have previously only been summarized for BMI. We therefore conducted a systematic review and meta-analysis of prospective studies to clarify the association between different adiposity measures and risk of atrial fibrillation. PubMed and Embase databases were searched up to October 24th 2016. Summary relative risks (RRs) were calculated using random effects models. Twenty-nine unique prospective studies (32 publications) were included...
February 13, 2017: European Journal of Epidemiology
Hannes Holm, Katarina Nägga, Erik D Nilsson, Olle Melander, Lennart Minthon, Erasmus Bachus, Artur Fedorowski, Martin Magnusson
The role of blood pressure (BP) changes in dementia is debatable. We aimed to analyse how resting and postural BP changes relate to incident dementia over a long-term follow-up. In the prospective population-based Malmö Preventive Project, 18,240 study participants (mean age: 45 ± 7 years, 63% male) were examined between 1974 and 1992 with resting and standing BP measurement, and re-examined between 2002 and 2006 at mean age of 68 ± 6 years with resting BP. A total of 428 participants (2.3%) were diagnosed with dementia through Dec 31, 2009...
February 11, 2017: European Journal of Epidemiology
Sofiane Kab, Johan Spinosi, Laura Chaperon, Aline Dugravot, Archana Singh-Manoux, Frédéric Moisan, Alexis Elbaz
Most studies on pesticides and Parkinson's disease (PD) focused on occupational exposure in farmers. Whether non-occupational exposure is associated with PD has been little explored. We investigated the association between agricultural characteristics and PD incidence in a French nationwide ecologic study. We hypothesized that persons living in regions with agricultural activities involving more intensive pesticide use would be at higher risk. We identified incident PD cases from French National Health Insurance databases (2010-2012)...
February 9, 2017: European Journal of Epidemiology
Ludvig B Rinde, Birgit Småbrekke, Erin M Hald, Ellen E Brodin, Inger Njølstad, Ellisiv B Mathiesen, Maja-Lisa Løchen, Tom Wilsgaard, Sigrid K Brækkan, Anders Vik, John-Bjarne Hansen
The association between myocardial infarction (MI) and future risk of incident cancer is scarcely investigated. Therefore, we aimed to study the risk of cancer after a first time MI in a large cohort recruited from a general population. Participants in a large population-based study without a previous history of MI or cancer (n = 28,763) were included and followed from baseline to date of cancer, death, migration or study end. Crude incidence rates (IRs) and hazard ratios (HRs) for cancer after MI were calculated...
February 7, 2017: European Journal of Epidemiology
Tanja Poulain, Ronny Baber, Mandy Vogel, Diana Pietzner, Toralf Kirsten, Anne Jurkutat, Andreas Hiemisch, Anja Hilbert, Jürgen Kratzsch, Joachim Thiery, Michael Fuchs, Christian Hirsch, Franziska G Rauscher, Markus Loeffler, Antje Körner, Matthias Nüchter, Wieland Kiess
The LIFE Child study is a large population-based longitudinal childhood cohort study conducted in the city of Leipzig, Germany. As a part of LIFE, a research project conducted at the Leipzig Research Center for Civilization Diseases, it aims to monitor healthy child development from birth to adulthood and to understand the development of lifestyle diseases such as obesity. The study consists of three interrelated cohorts; the birth cohort, the health cohort, and the obesity cohort. Depending on age and cohort, the comprehensive study program comprises different medical, psychological, and sociodemographic assessments as well as the collection of biological samples...
January 31, 2017: European Journal of Epidemiology
Jan P Vandenbroucke
No abstract text is available yet for this article.
January 24, 2017: European Journal of Epidemiology
Wei Xu, Huifu Wang, Yu Wan, Chenchen Tan, Jieqiong Li, Lan Tan, Jin-Tai Yu
It is widely believed that light-to-moderate alcohol intake may protect against dementia while excessive drinking may instead increase the risk. Nonetheless, these findings need cautious interpretations due to varying methodologies and lack of standard definition, which hindered our transferring into preventative practice. The objective of this study is to investigate the potential dose-response association between alcohol consumption and risk of dementia. A systematic search was conducted in electronic databases to identify relevant studies...
January 17, 2017: European Journal of Epidemiology
Anders Ahlbom
No abstract text is available yet for this article.
January 4, 2017: European Journal of Epidemiology
Marco Canevelli, Alessandro Blasimme, Matteo Cesari
No abstract text is available yet for this article.
January 2, 2017: European Journal of Epidemiology
Oxana Rotar, Maria Boyarinova, Alexander Orlov, Vladislav Solntsev, Yulia Zhernakova, Svetlana Shalnova, Alexander Deev, Alexandra Konradi, Elena Baranova, Irina Chazova, Sergey Boytsov, Eugene Shlyakhto
INTRODUCTION: The aim of the study was to estimate the prevalence of metabolically healthy obese (MHO) and metabolically unhealthy non-obese (MUNO) phenotypes in Russian population. DESIGN AND METHODS: In cross-sectional epidemiology survey "Epidemiology of cardiovascular diseases and its risk factors in some regions of the Russian Federation" a random sampling of 21,121 subjects (25-65 years), stratified by age and sex was involved. Anthropometry, blood pressure (BP) measurement and fasting blood-tests (glucose, lipids) were performed according to standard protocols...
December 30, 2016: European Journal of Epidemiology
Didier Raoult
No abstract text is available yet for this article.
December 24, 2016: European Journal of Epidemiology
Huandong Lin, Qian Li, Yu Hu, Chouwen Zhu, Hui Ma, Jian Gao, Jiong Wu, Hong Shen, Wenhai Jiang, Naiqing Zhao, Yiqing Yin, Baishen Pan, Johannes Jeekel, Albert Hofman, Xin Gao
OBJECTIVE: We set out to study the prevalence and combination of multiple non-communicable diseases among middle-aged and elderly people in the Shanghai Changfeng community, China. METHODS: A cross-sectional survey through questionnaire, physical, and laboratory examinations, color ultrasound and DXA was performed on a typical sample of 6038 residents (ages greater than 45-years-old) from the Shanghai Changfeng community between June 2009 and December 2012. RESULTS: The prevalence of chronic diseases (rating from high to low) was as follows: hypertension (55...
December 20, 2016: European Journal of Epidemiology
Kristine H Allin, Nele Friedrich, Maik Pietzner, Niels Grarup, Betina H Thuesen, Allan Linneberg, Charlotta Pisinger, Torben Hansen, Oluf Pedersen, Camilla H Sandholt
Lower serum vitamin B12 levels have been related to adverse metabolic health profiles, including adiposity. We used a Mendelian randomization design to test whether this relation might be causal. We included two Danish population-based studies (ntotal = 9311). Linear regression was used to test for associations between (1) serum vitamin B12 levels and body mass index (BMI), (2) genetic variants and serum vitamin B12 levels, and (3) genetic variants and BMI. The effect of a genetically determined decrease in serum vitamin B12 on BMI was estimated by instrumental variable regression...
December 19, 2016: European Journal of Epidemiology
Marjolein N Kooijman, Claudia J Kruithof, Cornelia M van Duijn, Liesbeth Duijts, Oscar H Franco, Marinus H van IJzendoorn, Johan C de Jongste, Caroline C W Klaver, Aad van der Lugt, Johan P Mackenbach, Henriëtte A Moll, Robin P Peeters, Hein Raat, Edmond H H M Rings, Fernando Rivadeneira, Marc P van der Schroeff, Eric A P Steegers, Henning Tiemeier, André G Uitterlinden, Frank C Verhulst, Eppo Wolvius, Janine F Felix, Vincent W V Jaddoe
The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidisciplinary study focuses on several health outcomes including behaviour and cognition, body composition, eye development, growth, hearing, heart and vascular development, infectious disease and immunity, oral health and facial growth, respiratory health, allergy and skin disorders of children and their parents...
December 2016: European Journal of Epidemiology
Hans-Olov Adami, Olof Nyrén
No abstract text is available yet for this article.
December 2016: European Journal of Epidemiology
Albert Hofman
No abstract text is available yet for this article.
December 2016: European Journal of Epidemiology
Corinna Seliger, Christoph R Meier, Claudia Becker, Susan S Jick, Ulrich Bogdahn, Peter Hau, Michael F Leitzmann
No abstract text is available yet for this article.
November 28, 2016: European Journal of Epidemiology
Sander Greenland
No abstract text is available yet for this article.
November 28, 2016: European Journal of Epidemiology
Eva Grill, Martin Müller, Ulrich Mansmann
No abstract text is available yet for this article.
November 28, 2016: European Journal of Epidemiology
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