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European Journal of Epidemiology

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https://www.readbyqxmd.com/read/28097521/alcohol-consumption-and-dementia-risk-a-dose-response-meta-analysis-of-prospective-studies
#1
Wei Xu, Huifu Wang, Yu Wan, Chenchen Tan, Jieqiong Li, Lan Tan, Jin-Tai Yu
It is widely believed that light-to-moderate alcohol intake may protect against dementia while excessive drinking may instead increase the risk. Nonetheless, these findings need cautious interpretations due to varying methodologies and lack of standard definition, which hindered our transferring into preventative practice. The objective of this study is to investigate the potential dose-response association between alcohol consumption and risk of dementia. A systematic search was conducted in electronic databases to identify relevant studies...
January 17, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28062968/enigmas-priorities-and-opportunities-in-cancer-epidemiology
#2
Hans-Olov Adami, Olof Nyrén
No abstract text is available yet for this article.
January 6, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28054220/significance-testing-why-does-it-prevail
#3
Anders Ahlbom
No abstract text is available yet for this article.
January 4, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28050746/a-note-of-thanks
#4
EDITORIAL
Albert Hofman
No abstract text is available yet for this article.
January 3, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28044219/societal-and-global-implications-of-the-dementia-epidemic-the-example-of-the-london-heathrow-airport
#5
LETTER
Marco Canevelli, Alessandro Blasimme, Matteo Cesari
No abstract text is available yet for this article.
January 2, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28039558/metabolically-healthy-obese-and-metabolically-unhealthy-non-obese-phenotypes-in-a-russian-population
#6
LETTER
Oxana Rotar, Maria Boyarinova, Alexander Orlov, Vladislav Solntsev, Yulia Zhernakova, Svetlana Shalnova, Alexander Deev, Alexandra Konradi, Elena Baranova, Irina Chazova, Sergey Boytsov, Eugene Shlyakhto
INTRODUCTION: The aim of the study was to estimate the prevalence of metabolically healthy obese (MHO) and metabolically unhealthy non-obese (MUNO) phenotypes in Russian population. DESIGN AND METHODS: In cross-sectional epidemiology survey "Epidemiology of cardiovascular diseases and its risk factors in some regions of the Russian Federation" a random sampling of 21,121 subjects (25-65 years), stratified by age and sex was involved. Anthropometry, blood pressure (BP) measurement and fasting blood-tests (glucose, lipids) were performed according to standard protocols...
December 30, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28013490/is-there-a-link-between-urinary-microbiota-and-bladder-cancer
#7
Didier Raoult
No abstract text is available yet for this article.
December 24, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27999971/the-prevalence-of-multiple-non-communicable-diseases-among-middle-aged-and-elderly-people-the-shanghai-changfeng-study
#8
LETTER
Huandong Lin, Qian Li, Yu Hu, Chouwen Zhu, Hui Ma, Jian Gao, Jiong Wu, Hong Shen, Wenhai Jiang, Naiqing Zhao, Yiqing Yin, Baishen Pan, Johannes Jeekel, Albert Hofman, Xin Gao
OBJECTIVE: We set out to study the prevalence and combination of multiple non-communicable diseases among middle-aged and elderly people in the Shanghai Changfeng community, China. METHODS: A cross-sectional survey through questionnaire, physical, and laboratory examinations, color ultrasound and DXA was performed on a typical sample of 6038 residents (ages greater than 45-years-old) from the Shanghai Changfeng community between June 2009 and December 2012. RESULTS: The prevalence of chronic diseases (rating from high to low) was as follows: hypertension (55...
December 20, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27995393/genetic-determinants-of-serum-vitamin-b12-and-their-relation-to-body-mass-index
#9
Kristine H Allin, Nele Friedrich, Maik Pietzner, Niels Grarup, Betina H Thuesen, Allan Linneberg, Charlotta Pisinger, Torben Hansen, Oluf Pedersen, Camilla H Sandholt
Lower serum vitamin B12 levels have been related to adverse metabolic health profiles, including adiposity. We used a Mendelian randomization design to test whether this relation might be causal. We included two Danish population-based studies (ntotal = 9311). Linear regression was used to test for associations between (1) serum vitamin B12 levels and body mass index (BMI), (2) genetic variants and serum vitamin B12 levels, and (3) genetic variants and BMI. The effect of a genetically determined decrease in serum vitamin B12 on BMI was estimated by instrumental variable regression...
December 19, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27896538/reply-to-greenland-a-serious-misinterpretation-of-a-consistent-inverse-association-of-statin-use-with-glioma-across-3-case-control-studies
#10
LETTER
Corinna Seliger, Christoph R Meier, Claudia Becker, Susan S Jick, Ulrich Bogdahn, Peter Hau, Michael F Leitzmann
No abstract text is available yet for this article.
November 28, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27896537/a-serious-misinterpretation-of-a-consistent-inverse-association-of-statin-use-with-glioma-across-3-case-control-studies
#11
Sander Greenland
No abstract text is available yet for this article.
November 28, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27896536/erratum-to-health-exploring-complexity-an-interdisciplinary-systems-approach-hec2016-28-august-2-september-2016-munich-germany
#12
Eva Grill, Martin Müller, Ulrich Mansmann
No abstract text is available yet for this article.
November 28, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27858205/statistical-inference-in-abstracts-of-major-medical-and-epidemiology-journals-1975-2014-a-systematic-review
#13
REVIEW
Andreas Stang, Markus Deckert, Charles Poole, Kenneth J Rothman
Since its introduction in the twentieth century, null hypothesis significance testing (NHST), a hybrid of significance testing (ST) advocated by Fisher and null hypothesis testing (NHT) developed by Neyman and Pearson, has become widely adopted but has also been a source of debate. The principal alternative to such testing is estimation with point estimates and confidence intervals (CI). Our aim was to estimate time trends in NHST, ST, NHT and CI reporting in abstracts of major medical and epidemiological journals...
November 17, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27832427/dna-methylation-changes-in-response-to-active-smoking-exposure-are-associated-with-leukocyte-telomere-length-among-older-adults
#14
Xu Gao, Ute Mons, Yan Zhang, Lutz Philipp Breitling, Hermann Brenner
Telomere length (TL) is associated with an increased risk of aging-related diseases. As a preventable environmental hazard of morbidity and mortality, smoking has been reported to promote TL attrition by producing a variety of oxidants and free radicals. Since DNA methylation has been demonstrated to play an important role in the pathways of smoking and smoking-induced diseases, this study aimed to address whether the smoking-associated DNA methylation changes could be associated with accelerated TL shortening...
November 10, 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28070760/the-generation-r-study-design-and-cohort-update-2017
#15
Marjolein N Kooijman, Claudia J Kruithof, Cornelia M van Duijn, Liesbeth Duijts, Oscar H Franco, Marinus H van IJzendoorn, Johan C de Jongste, Caroline C W Klaver, Aad van der Lugt, Johan P Mackenbach, Henriëtte A Moll, Robin P Peeters, Hein Raat, Edmond H H M Rings, Fernando Rivadeneira, Marc P van der Schroeff, Eric A P Steegers, Henning Tiemeier, André G Uitterlinden, Frank C Verhulst, Eppo Wolvius, Janine F Felix, Vincent W V Jaddoe
The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidisciplinary study focuses on several health outcomes including behaviour and cognition, body composition, eye development, growth, hearing, heart and vascular development, infectious disease and immunity, oral health and facial growth, respiratory health, allergy and skin disorders of children and their parents...
December 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28004211/from-paediatrics-to-geriatrics-a-life-course-perspective-on-the-mrc-national-survey-of-health-and-development
#16
Diana Kuh
No abstract text is available yet for this article.
November 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27995394/the-mrc-national-survey-of-health-and-development-reaches-age-70-maintaining-participation-at-older-ages-in-a-birth-cohort-study
#17
Diana Kuh, Andrew Wong, Imran Shah, Adam Moore, Maria Popham, Philip Curran, Daniel Davis, Nikhil Sharma, Marcus Richards, Mai Stafford, Rebecca Hardy, Rachel Cooper
A life course approach to ageing relies on maintaining participation rates in national birth cohorts and other long-term longitudinal studies. This reduces the risk of selective attrition biasing associations between lifetime risk factors and health outcomes in later life and ensures the studies remain as representative as possible of the original population. We report the participation patterns for a postal questionnaire and home visit at 68-69 years of study members in the MRC National Survey of Health and Development, the oldest and longest-running British birth cohort study...
November 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27817125/erratum-to-bridging-the-etiologic-and-prognostic-outlooks-in-individualized-assessment-of-absolute-risk-of-an-illness-application-in-lung-cancer
#18
Igor Karp, Marie-Pierre Sylvestre, Michal Abrahamowicz, Karen Leffondré, Jack Siemiatycki
No abstract text is available yet for this article.
November 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27738831/methods-for-individualized-assessment-of-absolute-risk-in-case-control-studies-should-be-weighted-carefully
#19
Kevin Ten Haaf, Ewout Willem Steyerberg
No abstract text is available yet for this article.
November 2016: European Journal of Epidemiology
https://www.readbyqxmd.com/read/27613171/associations-with-intraocular-pressure-across-europe-the-european-eye-epidemiology-e-3-consortium
#20
Anthony P Khawaja, Henriët Springelkamp, Catherine Creuzot-Garcher, Cécile Delcourt, Albert Hofman, René Höhn, Adriana I Iglesias, Roger C W Wolfs, Jean-François Korobelnik, Rufino Silva, Fotis Topouzis, Katie M Williams, Alain M Bron, Gabriëlle H S Buitendijk, Maria da Luz Cachulo, Audrey Cougnard-Grégoire, Jean-François Dartigues, Christopher J Hammond, Norbert Pfeiffer, Angeliki Salonikiou, Cornelia M van Duijn, Johannes R Vingerling, Robert N Luben, Alireza Mirshahi, Julia Lamparter, Caroline C W Klaver, Nomdo M Jansonius, Paul J Foster
Raised intraocular pressure (IOP) is the most important risk factor for developing glaucoma, the second commonest cause of blindness globally. Understanding associations with IOP and variations in IOP between countries may teach us about mechanisms underlying glaucoma. We examined cross-sectional associations with IOP in 43,500 European adults from 12 cohort studies belonging to the European Eye Epidemiology (E(3)) consortium. Each study conducted multivariable linear regression with IOP as the outcome variable and results were pooled using random effects meta-analysis...
November 2016: European Journal of Epidemiology
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