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Annals of Saudi Medicine

Ahmad E Aboshaiqah, Joel G Patalagsa
No abstract text is available yet for this article.
November 2018: Annals of Saudi Medicine
Mustafa Afifi
No abstract text is available yet for this article.
November 2018: Annals of Saudi Medicine
Nishant Nayyar, Shikha Sood, Ashwani Tomar
No abstract text is available yet for this article.
November 2018: Annals of Saudi Medicine
Frieda-Elsje Dreyer, Ganiy Opeyemi Abdulrahman, Gareth Waring, Kim Hinshaw
Placental steroid sulphatase deficiency (SSD) is an X-linked inborn error of metabolism. Congenital X-linked ichthyosis (XLI) is a genetic disorder of keratinisation caused by steroid sulphatase (STS) deficiency, which results in a scaling skin condition in male infants shortly after birth. It may be associated with failed induction of labor and prolonged labor leading to cesarean delivery due to 'cervical dystocia'. We present two cases of congenital ichthyosis. Thorough counselling of women with a previously affected pregnancy during the antenatal period should include discussion about mode of delivery and a critical review of the complexities of prenatal diagnosis in this condition...
November 2018: Annals of Saudi Medicine
Ihab Mokhtar Weheba, Abeer Mohamed Abdelsayed, Rand Khaled Arnaout, Mohamed Omar Zeitouni, Khalid Fahad Mobaireek, Tahani Bakheet AlHarthi, Abdullah Fahad Mobeireek
BACKGROUND: Although anti-IgE therapy has been shown to offer numerous benefits, we suspect it is underutilized locally. To date, there are no studies on any aspect of its use in the Arab region. There is also no information on whether physicians follow current guidelines nor on patient response to this form of therapy. OBJECTIVE: Assess the use of omalizumab for patients with difficult asthma at a tertiary care center. DESIGN: Retrospective, descriptive...
November 2018: Annals of Saudi Medicine
Ahmed L Fathala, Faisal Mohammed Alabdulkarim, Mohamed Shoukri, Muhannad Alanazi
BACKGROUND: Currently, there are no data on the prevalence of breast arterial calcification (BAC) in Saudi women. Furthermore, there are no data on the relationship between BAC and coronary artery calcium score (CACS) as a coronary artery disease (CAD) risk factor in Saudi women who undergo mammography. OBJECTIVE: Examine the role of BAC as a potential female-specific risk factor for CAD in Saudi women in order to investigate the relationship between BAC and CACS in women who undergo a screening mammography, and study the relationship between BAC and CAD risk factors, including age, diabetes mellitus, hypertension, chronic kidney disease (CKD), dyslipidemia, and family history of CAD...
November 2018: Annals of Saudi Medicine
Heyam Awad, Amer Abu-Shanab, Noor Hammad, Amani Atallah, Mai Abdulattif
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide. In the West, the incidence has stabilized or decreased. There are only occasional published studies that describe the epidemiology of CRC and its changing trends in Jordan and other Middle Eastern countries. OBJECTIVES: Describe the epidemiological features of CRC, predict future trends and compare the results with those from other Arab and Middle Eastern countries and the West. DESIGN: Retrospective epidemiologic study...
November 2018: Annals of Saudi Medicine
Chung-Huei Huang, Yu-Yao Huang, Brend Ray-Sea Hsu
BACKGROUND: Sodium-glucose cotransporter 2 inhibitors (SGLT2is, gliflozins) are associated with lower all-cause mortality than other anti-diabetic agents in patients with type 2 diabetes. In patients who may benefit from SGLT2is, but cannot add them to a dipeptidyl peptidase-4 inhibitor (DPP4i, gliptin) treatment for various reasons, replacement of the DPP4i with a SGLT2i may be considered. OBJECTIVES: Evaluate changes in metabolic parameters in patients with diabetes after replacing a DPP4i with the SGLT2i empagliflozin...
November 2018: Annals of Saudi Medicine
Waleed Mahallawi
BACKGROUND: Globally, about 300 million people are infected with hepatitis B virus (HBV). Among the effective approaches to fight HBV infection is immunization. In 1989, an obligatory hepatitis B vaccine program was launched in Saudi Arabia. OBJECTIVE: Assess hepatitis B surface antibody (anti-HBs) levels among the medical students before and after receiving booster doses of HBV vaccine. DESIGN: Cross-sectional. SETTING: Taibah University...
November 2018: Annals of Saudi Medicine
Mohammed S Alayed, Mohamed A Qureshi, Saif Ahmed, Ali S Alqahtani, Awad M Al-Qahtani, Khalid Alshaybari, Majed Alshahrani, Ahmed M Asaad
BACKGROUND: Zika virus (ZIKV) is a teratogenic flavivirus that can cause microcephaly. Its main vector, Aedes aegypti, has been previ.ously identified in Saudi Arabia, but no ZIKV infection has yet been reported. Nevertheless, the country is at risk from ZIKV because it receives many travelers throughout the year, including pilgrims from ZIKV-endemic countries. OBJECTIVES: Screen asymptomatic pregnant mothers and their newborns attending a major hospital in the Najran region for subclinical or past infections with ZIKV, using ELISA and RT-PCR...
November 2018: Annals of Saudi Medicine
Nahed Alquwez, Jonas Preposi Cruz, Joseph U Almazan, Majed Sulaiman Alamri, Jennifer J Mesde
BACKGROUND: With the steadily increasing size of its elderly popu.lation, Saudi Arabia is currently trying to meet the demands for com.petent care for older people. However, the lack of a valid and reliable measurement instrument in the Arab Peninsula hinders related studies among nursing students in this part of the globe. Given the importance of nursing students' attitudes toward working with older people, a specialized tool that can provide an accurate assessment of students' attitudes toward older adults is necessary...
November 2018: Annals of Saudi Medicine
Aidah Abdul-Aziz AlRammah, Shaher Mesfer Alqahtani, Ahmed Gasim Elzubair, Suha Saleh Al-Saleh, Wajid Syed, Abdul Aziz Khalid, Hend Homoud Al-Shammari
BACKGROUND: Child sexual abuse (CSA) has serious consequences that can affect the physical, social and mental health of a child. In the last two decades, concern about CSA has increased around the world including Saudi Arabia. OBJECTIVE: Evaluate factors associated with parental perceptions and knowledge of CSA. DESIGN: Cross-sectional survey. SETTINGS: Primary health care clinic. SUBJECTS AND METHODS: Simple random sampling was used to select participants...
November 2018: Annals of Saudi Medicine
Siew Chung Cheah, Hui Tong Wong, Chin Yee Lau
No abstract text is available yet for this article.
September 2018: Annals of Saudi Medicine
Hebah Mohammadsalam Musalem, Aljoharah Abdulaziz Alshaikh, Lin M Tuleimat, Saad Alajlan
We used a topical formulation of sirolimus for treating port wine stain (PWS). Although pulsed dye laser (PDL) is the current treatment of choice for PWS, fast neovascularization after treatment is a major drawback. With PDL therapy there has been insufficient improvement and frustrating side effects. The objective was to study the efficacy and safety of combining topical sirolimus with PDL as dual therapy in managing PWS. We report five PWS cases that were treated with PDL initially, followed by 0.5-1% topical sirolimus...
September 2018: Annals of Saudi Medicine
Jing Li, Dezhi Liu, Jinfeng Wu, Xiaoyong Fan, Qianqian Dong
BACKGROUND: The safety and efficacy of dapoxetine for the treatment of premature ejaculation (PE) is still controversial. Thus, we decided to conduct a meta-analysis using trial sequential analysis (TSA) to determine the sufficiency of conclusions. OBJECTIVE: Evaluate the efficacy and safety of dapoxetine in the treatment of patients with PE and assess the reliability of the findings. DESIGN: Meta-analysis of randomized controlled trials (RCTs)...
September 2018: Annals of Saudi Medicine
Abdulrahman A Aljumah, Hadi Kuriry, Nabiha Faisal, Hamdan Alghamdi
BACKGROUND: Hepatocellular carcinoma (HCC) is a primary liver malignancy and one of the most common cancers worldwide. Few studies in Saudi Arabia have compared the clinicopathologic characteristics of HCC caused by hepatitis B virus (HBV) versus hepatitis C virus (HCV) and their effect on patient survival and prognosis. OBJECTIVES: Identify differences in clinicopathological characteristics and outcomes of hepatocellular carcinoma (HCC) caused by HBV versus HCV...
September 2018: Annals of Saudi Medicine
Tracy Louise Ellison, Maha Alharbi, Morad Alkaf, Shamad Elimam, Mariam Alfaries, Randa Al Nounou, Rasheed Nasr, Tarek Owaidah
BACKGROUND: Total laboratory automation (TLA) is a relatively new way of improving the management of high volume clinical laboratories. TLA may reduce staff, reduce operating costs, decrease testing time and provide enhanced process control. OBJECTIVES: Establish a cost efficient TLA that is less labor intensive, improves productivity and reduces turnaround time (TAT). DESIGN: Implementation of TLA for random glucose and troponin-T as sentinel tests to compare change in TAT...
September 2018: Annals of Saudi Medicine
Abdulwahab Elbarsha, Maisoon Elhemri, Sami A Lawgaly, Ashraf Rajab, Badia Almoghrabi, Rafik Ramadan Elmehdawia
BACKGROUND: Fasting during Ramadan is a challenge for Muslim patients with diabetes and for their healthcare providers. However, data on the effects of Ramadan fasting on hospital admissions and outcomes in patients with diabetes are scarce. OBJECTIVES: Evaluate the characteristics of patients with diabetes admitted during the fasting month of Ramadan compared with the non-fasting month of Dhu al-Qidah. DESIGN: A retrospective cohort study medical record review...
September 2018: Annals of Saudi Medicine
Khalid S Aljabri, Samia A Bokhari, Muneera A Al, Patan Murthuza Khan
BACKGROUND: Thyroid carcinoma (TC) is the ninth most common site of all cancers in women in the world and the second most common malignancy in Saudi Arabia. This reports updates data on the epidemiology of the disease in Saudi Arabia. OBJECTIVE: Describe and interpret changes in the frequency of TC to compare with other populations and determine proportions of certain histological types of TC. DESIGN: Medical record review. SETTING: Military hospital in Jeddah, Saudi Arabia...
September 2018: Annals of Saudi Medicine
Fatima Nouri Obeidat, Mamoun Ahram, Ali Al-Khader, Suzan Al Mbaideen, Huda Hassan, Bushra Altarawneh, Khairat Battah
BACKGROUND: The clinical relevance of androgen receptors (ARs) expressed in breast cancer cells and the suggested prognostic impact has been an area of active research. The prevalence rate of AR expression in breast cancer has never been reported among Jordanian patients. OBJECTIVE: Determine the expression rate of ARs among invasive ductal breast cancer cases of different stages and molecular subtypes. Also, analyze the relationship between AR expression and clinicopathologic and immunohistochemical criteria, and assess the impact of AR expression on survival...
September 2018: Annals of Saudi Medicine
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