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European Journal of Surgical Oncology

Darko Zdravkovic, Nebojsa Ivanovic, Natasa Colakovic, Marija Zdravkovic
No abstract text is available yet for this article.
July 7, 2018: European Journal of Surgical Oncology
Kim Govaerts, K Chandrakumaran, Norman J Carr, Thomas D Cecil, Sanjeev Dayal, Faheez Mohamed, Andrew Thrower, Brendan J Moran
AIM: Pseudomyxoma peritonei (PMP) is an uncommon malignancy, generally originating from a ruptured epithelial tumour of the appendix. Despite successful cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), some patients recur. Currently there are no guidelines on the methods, frequency and intensity of follow-up. METHODS: Between 1994 and 2016, 1070 patients underwent surgery for a perforated epithelial tumour of the appendix, predominantly with PMP...
July 6, 2018: European Journal of Surgical Oncology
Luciano Tarantino, Giuseppina Busto, Aurelio Nasto, Riccardo Aurelio Nasto, Paolo Tarantino, Raffaele Fristachi, Luigi Cacace, Sara Bortone
AIM: We evaluated feasibility, safety and efficacy of Electrochemotherapy (ECT) in a prospective series of patients with unresectable Perihilar-Cholangiocarcinoma (PHCCA). PATIENTS AND METHODS: Five patients with PHCCA underwent ECT. Three patients underwent percutaneous ECT of a single PHCCA nodule. One patient underwent resection of a nodule in the IV segment and intraoperative ECT of a large PHCCA in the VIII segment. Another patient underwent percutaneous ECT of a large PHCCA recurrence after left lobectomy and RF ablation of a synchronous metastasis in the VI segment...
July 6, 2018: European Journal of Surgical Oncology
Si-Qi Qiu, Monique D Dorrius, Steven J de Jongh, Liesbeth Jansen, Jakob de Vries, Carolien P Schröder, Guo-Jun Zhang, Elisabeth G E de Vries, Bert van der Vegt, Gooitzen M van Dam
PURPOSE: Around 15%-30% of patients receiving breast-conserving surgery (BCS) for invasive breast carcinoma or ductal carcinoma in situ (DCIS) need a reoperation due to tumor-positive margins at final histopathology. Currently available intraoperative surgical margin assessment modalities all have specific limitations. Therefore, we aimed to assess the feasibility and accuracy of micro-computed tomography (micro-CT) as a novel method for intraoperative margin assessment in BCS. METHODS: Lumpectomy specimens from 30 consecutive patients diagnosed with invasive breast cancer or DCIS were imaged using a micro-CT...
July 3, 2018: European Journal of Surgical Oncology
Antonio Sommariva, Ana-Maria Forsea, Domenic Agius, Paolo Antonio Ascierto, Esther Bastiaannet, Lorenzo Borgognoni, Anna Demetriou, Claus Garbe, Zivana Gavric, Marko Hocevar, Kaire Innos, Siri Larønningen, Marieke Louwman, Trude Eid Robsahm, Piotr Rutkwoski, Alexander van Akkooi, Manuel Zorzi, Sandro Pasquali, Cornelis van de Velde, Carlo Riccardo Rossi
BACKGROUND: A significant disparity regarding survival outcome for melanoma among European regions is well recognized and access to high quality care for European melanoma patients needs to be improved. There is an unmet need for the implementation of minimal standard of care within defined clinical pathways and Quality Assurance (QA) indicators. OBJECTIVE: The EU-MELACARE study aims to identify shared variables for cutaneous melanoma cases recorded in melanoma registries across Europe...
July 3, 2018: European Journal of Surgical Oncology
Björn Bolmstrand, Per J Nilsson, Torbjörn Holm, Christian Buchli, Gabriella Palmer
BACKGROUND: Multi-visceral resection, including parts of the urinary tract, is sometimes warranted to achieve cancer clear resection margins and optimize survival in patients with locally advanced colorectal and anal cancer. The aim of this study was to assess morbidity after urinary tract reconstruction dictated by colorectal and anal malignancy and to identify potential predictors of urological complications. METHODS: All patients undergoing surgery for colorectal or anal malignancy, including urinary tract resection and synchronous reconstruction, performed at the Karolinska University Hospital during 2004-2015 were included in this retrospective cohort study...
July 2, 2018: European Journal of Surgical Oncology
Ashok R Shaha
No abstract text is available yet for this article.
June 25, 2018: European Journal of Surgical Oncology
Deena P Harji, Abigail Vallance, Jenny Selgimann, Simon Bach, Faheez Mohamed, Julia Brown, Nicola Fearnhead
BACKGROUND: Management of the primary tumour in the presence of unresectable metastatic colorectal cancer (mCRC) is controversial. The role of primary tumour resection (PTR) has been investigated by a number of retrospective cohort studies, with a number on going randomised controlled trials. The aim of this study was to identify the clinical and patient-reported outcomes currently reported in studies that evaluate the role of PTR in mCRC. METHODS: Literature searches were performed in MEDLINE (via OvidSP) (1966-June 2017), EMBASE (via OvidSP) and the Cochrane Library using terms related to colorectal cancer and primary tumour resection...
June 23, 2018: European Journal of Surgical Oncology
Elie Isenberg-Grzeda, Meredith MacGregor, Afton Bergel, Stacy Eagle, Fernando Espi Forcen, Reema Mehta, Konstantina Matsoukas, Jonathan Wills, Diane Reidy-Lagunes, Yesne Alici
No abstract text is available yet for this article.
June 19, 2018: European Journal of Surgical Oncology
H L Tattersall, A Gronchi
No abstract text is available yet for this article.
June 18, 2018: European Journal of Surgical Oncology
Pim B Olthof, Andreas A Schnitzbauer, Erik Schadde
Ten years ago the first patient underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS). This report aimed to critically review literature on ALPPS in terms of methods, outcomes, and bias. In total, 237 English papers on ALPPS were identified, 75 (32%) were letters and 43 (18%) case-reports. Forty-nine single-center series reported a median 10 patients, with 0-69% morbidity and 0-50% mortality. The indications for ALPPS were reported in 35% and 47% reported on modifications...
June 18, 2018: European Journal of Surgical Oncology
Svanheiður Lóa Rafnsdóttir, Riccardo A Audisio
Strict criteria to identify Inflammatory Breast Cancer (IBC) have been made available - these are based on pathological as well as clinical observations. It is mandatory to confirm the criteria used in any further report. Scientific evidence accumulated so far is confusing, and unclear therefore no hard conclusion can be drawn from the available literature on the management of IBC. The advent of new medications results into an up-to-date management and different outcomes. It is mandatory to follow these criteria if reliable guidelines are to be made available in the next future...
June 18, 2018: European Journal of Surgical Oncology
Riccardo A Audisio
No abstract text is available yet for this article.
June 18, 2018: European Journal of Surgical Oncology
Kadri Altundag
No abstract text is available yet for this article.
June 18, 2018: European Journal of Surgical Oncology
Lihua Liu, Chan Oh, Jae Hyung Heo, Hee Sung Park, Kyungmin Lee, Jae Won Chang, Seung-Nam Jung, Bon Seok Koo
BACKGROUND: Extrathyroidal extension (ETE) is a risk factor for poor papillary thyroid carcinoma (PTC) outcomes. However, the clinical significance of ETE according to primary tumor size has not been well-established. The purpose of this study was to compare differences in clinical outcomes, according to the presence and extent of ETE, between different primary tumor size groups. METHODS: In total, 381 patients with PTC underwent total thyroidectomy with or without lymph node (LN) dissection from 2004 to 2010...
June 12, 2018: European Journal of Surgical Oncology
Shu-Fang Huang, Ti-Hsuan Chien, Wen-Liang Fang, Frank Wang, Chun-Yi Tsai, Jun-Te Hsu, Chun-Nan Yeh, Tse-Ching Chen, Ren-Chin Wu, Cheng-Tang Chiu, Ta-Sen Yeh
BACKGROUND: The 8th edition of AJCC gastric cancer pathological staging system (AJCC8) derived from the IGCA database needs an external validated in cohorts with higher proportion of advanced disease. PATIENTS AND METHODS: A total of 5386 gastric cancer patients treated at Chang Gung Memorial Hospital (CGMH) and Veteran General Hospital in Taipei (TVGH) were enrolled. Clinicopathological data of the IGCA series and the CGMH/TVGH cohort were compared. Cumulative survival curves of the CGMH/TVGH cohort as stratified by the AJCC7 and the AJCC8 were compared...
June 11, 2018: European Journal of Surgical Oncology
Steffi Hartmann, Toralf Reimer, Bernd Gerber, Johannes Stubert, Bernd Stengel, Angrit Stachs
INTRODUCTION: Clipping and selective removal of initially suspicious axillary lymph nodes in breast cancer patients who have been sonographically down-staged by primary systemic therapy improves the accuracy of surgical staging and provides the opportunity for more conservative axillary surgery. This study evaluated whether preoperative ultrasound-guided wire localization of the clipped node is useful for routine clinical practice. MATERIAL AND METHODS: This prospective, single-center feasibility trial included patients with invasive breast cancer (cT1-3N1-3M0) treated by primary systemic therapy...
June 9, 2018: European Journal of Surgical Oncology
Michael P M de Neree Tot Babberich, Robin Detering, Jan Willem T Dekker, Marloes A Elferink, Rob A E M Tollenaar, Michel W J M Wouters, Pieter J Tanis
INTRODUCTION: The efficacy of auditing is still a subject of debate and concerns exist whether auditing promotes risk averse behaviour of physicians. This study evaluates the achievements made in colorectal cancer surgery since the start of a national clinical audit and assesses potential signs of risk averse behaviour. METHODS: Data were extracted from the Dutch ColoRectal Audit (2009-2016). Trends in outcomes were evaluated by uni and multivariable analyses. Patients were stratified according to operative risks and changes in outcomes were expressed as absolute (ARR) and relative risk reduction (RRR)...
June 8, 2018: European Journal of Surgical Oncology
Charlotte S Voskuilen, Elisabeth E Fransen van de Putte, Jose I Pérez-Reggeti, Erik van Werkhoven, Laura S Mertens, Bas W G van Rhijn, Mohamed Saad, Axel Bex, Xavier Cathelineau, Henk G van der Poel, Simon Horenblas, Rafael Sanchez-Salas, Richard P Meijer
PURPOSE: To assess long-term functional and oncologic outcomes of prostate sparing cystectomy (PSC) as a sexuality-preserving alternative to radical cystectomy in a selected group of bladder cancer (BC) patients. MATERIALS AND METHODS: Between 1995 and 2014, 185 BC patients underwent PSC according to one of two standardized procedures at two centers. All patients had received extensive evaluation to rule out prostate cancer and BC at the bladder neck and prostatic urethra (PU), including prostate specific antigen blood analysis, transrectal ultrasound and/or prostate biopsies, PU biopsies and/or PU frozen section analysis...
June 8, 2018: European Journal of Surgical Oncology
Jonathan D Stevenson, Minna K Laitinen, Michael C Parry, Vaiyapuri Sumathi, Robert J Grimer, Lee M Jeys
INTRODUCTION: Chondrosarcoma (CS) is the second most common primary bone sarcoma with no clear role for adjuvant therapy. The purpose of this study was to investigate (1) the relationship between surgical excision margins and local recurrence free survival (LRFS), and (2) the role of local recurrence (LR) in disease specific survival (DSS) in CS of the extremity and pelvis. MATERIAL AND METHODS: 341 pelvic and extremity CS diagnosed between 2003 and 2015 were studied retrospectively...
June 8, 2018: European Journal of Surgical Oncology
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