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European Journal of Surgical Oncology

I T Rubio, L Wyld, A Esgueva, T Kovacs, M J Cardoso, M Leidenius, S Bianca, A Kolacinska, L Marotti, C Lecoq, L Biganzoli, R Audisio
BACKGROUND: At present there is a lack of standardization of training in breast cancer surgery across Europe. The aim of this survey was to assess current practice in Europe regarding training in breast cancer (BC) surgery. MATERIAL AND METHODS: General surgeons, surgical oncologists, gynecologist, and plastic surgeons in Europe were invited to participate in this bespoke survey including 19 questions. RESULTS: The survey was sent to 3.000 surgical oncologists across Europe...
January 5, 2019: European Journal of Surgical Oncology
Bayu Brahma, Takumi Yamamoto
Breast cancer is the most common cancer in Dharmais hospital. The treatment can give rise to breast cancer treatment-related lymphedema (BCRL) that will cause significant morbidities. Based on author's (BB) patient series in Dharmais hospital, BCRL occurred in 27.7% after axillary lymph nodes dissection (ALND). The development of diagnostic modalities as well as lymphatic microsurgery have become promising instruments for lymphedema treatment. To date, modern approach of lymphedema care and surgical intervention have not been recognized and established in Indonesia...
January 4, 2019: European Journal of Surgical Oncology
Jason Ramsingh, Patrick O'Dwyer, Carol Watson
BACKGROUND: Adrenal metastases can arise from different primary sites. Surgical resection of the adrenal gland in patients with isolated metastases may offer improved survival in many of these patients. However, the benefit of surgery in this heterogenous group is often disputed. The aim of this study was to identify patients undergoing adrenalectomy for isolated metastases and to describe survival outcomes based on origin of the primary malignancy. METHODS: Patients undergoing surgery for isolated adrenal metastases were retrospectively analysed from a prospectively kept database...
January 4, 2019: European Journal of Surgical Oncology
L S E van Egdom, M Lagendijk, M H van der Kemp, J H van Dam, M A M Mureau, J A Hazelzet, L B Koppert
PURPOSE: Adding value of care to patients is crucial for all stakeholders. The use of both provider and patient reported outcome data was implemented in a single academic breast cancer center. We describe the development of the outcomes set, data integration within electronical health records (EHR) and clinical use. METHODS: An Integrated Practice Unit (IPU) was constructed providing the full care cycle for breast cancer patients. Provider reported outcomes and patient reported outcomes (PROs) were defined, reflecting the entire cycle of care and long-term sustainability of quality of life...
January 4, 2019: European Journal of Surgical Oncology
Roneil Parikh, Sanjana Shah, Vikrant Dhurandhar, Nayef Alzahrani, Oliver M Fisher, Arief Arrowaili, Winston Liauw, David Morris
PURPOSE: CRS/HIPEC has evolved as an effective method for management of selected patients with peritoneal metastatic disease. Abdominal wall resection (AWR) is often required, and may require complex reconstructions, such as component separation (CST) leading to wound dehiscence (WD) and wound complications (WC). The purpose of our study was to analyse factors contributing to wound complications and wound recurrence (WR). METHODS: Retrospective review of a prospective database of 1074 patients undergoing CRS/HIPEC procedures from 1996 to 2017 at St George Hospital...
December 29, 2018: European Journal of Surgical Oncology
E Heeg, K Schreuder, P E R Spronk, J C Oosterwijk, P J Marang-van de Mheen, S Siesling, M T F D Vrancken Peeters
PURPOSE: Patients may transfer of hospital for clinical reasons but this may delay time to treatment. The purpose of this study is to provide insight in the extent of hospital transfer in breast cancer care; which type of patients transfer and what is the impact on time to treatment. METHODS: We included 41,413 breast cancer patients registered in the Netherlands Cancer Registry between 2014 and 2016. We investigated transfer of hospital between diagnosis and first treatment being surgery or neoadjuvant chemotherapy (NAC)...
December 29, 2018: European Journal of Surgical Oncology
Bhavneet Singh, Gurkirat Singh, Nayef Alzahrani, Arief Arrowaili, David L Morris
OBJECTIVES: To assess the impact of short and long term outcomes of diaphragmatic interventions in cyto-reductive surgery (CRS) and intra-peritoneal chemotherapy (IPC). METHODS: 1230 consecutive CRS/IPC procedures were preformed between 1996 and 2018 in Sydney, Australia. Redo procedures and incomplete cyto-reductions were excluded. Among these, 599 underwent diaphragmatic intervention. Preoperative heterogeneity was assessed for in 6 parameters and addressed with propensity score matching...
December 29, 2018: European Journal of Surgical Oncology
Teresa Schreckenbach, Helga Hübert, Christine Koch, Jörg Bojunga, Andreas A Schnitzbauer, Wolf O Bechstein, Katharina Holzer
BACKGROUND: It remains unclear whether liver resection as part of multimodal therapy of neuroendocrine liver metastases (NELM) is superior to non-surgical (interventional and medication-based) treatment alone. This study should determine if patients with NELM undergoing hepatic surgery in addition to non-surgical treatment have improved overall survival compared to patients undergoing non-surgical therapy alone. METHODS: 123 patients undergoing treatment of NELM between 1995 and 2014 were included in this retrospective cohort study...
December 28, 2018: European Journal of Surgical Oncology
J A W Hagemans, W J Alberda, M Verstegen, J H W de Wilt, C Verhoef, M A Elferink, J W A Burger
BACKGROUND: Clinically staged T1-3 rectal cancer (cT1-3) is generally treated by total mesorectal excision(TME) with or without neoadjuvant therapy and sometimes requires beyond TME-surgery, whereas cT4 rectal cancer often requires both. This study evaluates the outcome of cT1-3 and cT4 rectal cancer according to hospital volume. METHODS: Patients undergoing rectal cancer surgery between 2005 and 2013 in the Netherlands were included from the National Cancer Registry...
December 26, 2018: European Journal of Surgical Oncology
Weiqiang Qiao, Heyang Liu, Wanying Guo, Peng Li, Miao Deng
BACKGROUND: The prognostic value of syndecan-1 (SDC1, also called CD138) in breast cancer remains controversial. Therefore, we performed a meta-analysis to assess the clinical significance of SDC1 expression in breast cancer. MATERIALS AND METHODS: Various databases were searched to evaluate possible correlations between SDC1 protein or mRNA expression and prognostic significance in breast cancer. Pooled hazard ratios (HRs) and odds ratios (ORs) with 95% confidence intervals (CIs) were applied to perform a quantitative meta-analysis...
December 25, 2018: European Journal of Surgical Oncology
Adriana Handra-Luca
No abstract text is available yet for this article.
December 21, 2018: European Journal of Surgical Oncology
L Graziosi, E Marino, A Donini
BACKGROUND: The objective of this study was to compare the 7th and the 8th edition of American Joint Committee on Cancer staging system (AJCC TNM) in terms of better stratification in our gastric cancer resected patients. METHODS AND MATERIALS: A retrospective analysis of a single western center series was made. Patients who underwent surgery from January 2004 to December 2016 were enrolled in the study. We compared survival rates across patients classified according to the 7th and the 8th AJCC TNM staging system...
December 21, 2018: European Journal of Surgical Oncology
Zhen-Li Li, Jiong-Jie Yu, Jun-Wu Guo, Cheng-Jun Sui, Bing-Hua Dai, Wan-Guang Zhang, Ting-Hao Chen, Chao Li, Wei-Min Gu, Ya-Hao Zhou, Hong Wang, Yao-Ming Zhang, Xian-Hai Mao, Timothy M Pawlik, Ming-Da Wang, Lei Liang, Han Wu, Wan Yee Lau, Meng-Chao Wu, Feng Shen, Tian Yang
BACKGROUND: The role of liver resection for multinodular (≥3 nodules) hepatocellular carcinoma (HCC) remains unclear, especially among patients with severe underlying liver disease. We sought to evaluate surgical outcomes among patients with cirrhosis and multinodular HCC undergoing liver resection. METHODS: Using a multicenter database, outcomes among cirrhotic patients who underwent curative-intent resection of HCC were examined stratified according to the presence or absence of multinodular disease...
December 21, 2018: European Journal of Surgical Oncology
Tao Chen, Lili Xu, Liangying Ye, Haibo Qiu, Yanfeng Hu, Hao Liu, Zhiwei Zhou, Guoxin Li, Jiang Yu
BACKGROUND: This study aimed to build a new risk stratification nomogram for gastrointestinal stromal tumors (GISTs) focused on a popular factor Ki-67 to enable individualized and precise predictions of the most suitable candidates for imatinib therapy. METHODS: We retrospectively collected clinicopathologic data of the patients diagnosed with GISTs from January 1998 to December 2015 at Southern Medical University Nanfang Hospital as the experiment group. And patients with GISTs at the Sun Yat-sen University Cancer Center from January 2007 to December 2012 were included as the validation group...
December 21, 2018: European Journal of Surgical Oncology
Nadine L de Boer, Jan A W Hagemans, Bob T A Schultze, Alexandra R M Brandt-Kerkhof, Eva V E Madsen, Cornelis Verhoef, Jacobus W A Burger
INTRODUCTION: Patients with peritoneal carcinomatosis who do not have curative treatment options often develop acute obstructive symptoms and when conservative management fails, surgical treatment is the remaining option. However, palliative surgery is associated with high morbidity and mortality and the chance of success is unclear. The aim of this study was to evaluate outcomes of palliative surgery and to provide guidance for surgeons, medical oncologists and patients in their decision-making...
December 21, 2018: European Journal of Surgical Oncology
Jan P Pennings, Robbert J de Haas, Kawthar J A Murshid, Koert P de Jong, Rudi A J O Dierckx, Thomas C Kwee
INTRODUCTION: This study aimed to determine the positive predictive value (PPV) of positron emission tomography/computed tomography (PET/CT) with an 18 F-fluoro-2-deoxy-D-glucose (FDG)-avid presacral lesion for locally recurrent rectal cancer, and the additional value of magnetic resonance imaging (MRI), including diffusion-weighted imaging (DWI). MATERIALS AND METHODS: This retrospective study included 38 patients who completed primary rectal cancer treatment and who presented with a suspicious FDG-avid presacral lesion on PET/CT...
December 21, 2018: European Journal of Surgical Oncology
F G Uzunoglu, M-N Welte, F Gavazzi, L Maggino, J Perinel, R Salvia, M Janot, M Reeh, D Perez, M Montorsi, A Zerbi, M Adham, W Uhl, C Bassi, J R Izbicki, G Malleo, M Bockhorn
BACKGROUND: The MDACC group recommends to extend the current borderline classification for pancreatic cancer into three groups: type A patients with resectable/borderline tumor anatomy, type B with resectable/borderline resectable tumor anatomy and clinical findings suspicious for extrapancreatic disease and type C with borderline resectable and marginal performance status/severe pre-existing comorbidity profile or age>80. This study intents to evaluate the proposed borderline classification system in a multicenter patient cohort without neoadjuvant treatment...
December 19, 2018: European Journal of Surgical Oncology
Michael C Parry, Minna K Laitinen, Jose I Albergo, Czar L Gaston, Jonathan D Stevenson, Robert J Grimer, Lee M Jeys
INTRODUCTION: Endoprostheses in the treatment of extremity sarcomas are associated with late complications including periprosthetic infection. This study analysed the incidence of infection in patients undergoing endoprosthetic replacement (EPR) with a silver-coated prosthesis. MATERIALS AND METHODS: The study comprised a retrospective single centre study of 394 consecutive patients treated with resection and EPR for primary extremity bone tumours. RESULTS: 89 patients at risk for infection were treated with a silver-coated (Agluna®) EPR (22...
December 14, 2018: European Journal of Surgical Oncology
Jony van Hilst, Maarten Korrel, Thijs de Rooij, Sanne Lof, Olivier R Busch, Bas Groot Koerkamp, David A Kooby, Susan van Dieren, Mo Abu Hilal, Marc G Besselink
In the absence of randomized trials, uncertainty regarding the oncologic efficacy of minimally invasive distal pancreatectomy (MIDP) remains. This systematic review aimed to compare oncologic outcomes after MIDP (laparoscopic or robot-assisted) and open distal pancreatectomy (ODP) in patients with pancreatic ductal adenocarcinoma (PDAC). Matched and non-matched studies were included. Pooled analyses were performed for pathology (e.g., microscopically radical (R0) resection and lymph node retrieval) and oncologic outcomes (e...
December 13, 2018: European Journal of Surgical Oncology
Janneke J C Tersteeg, Levi M van Esch, Paul D Gobardhan, Peter A M Kint, Tom Rozema, Rogier M P H Crolla, Jennifer M J Schreinemakers
INTRODUCTION: To reduce the risk of local recurrence after rectal cancer surgery, neoadjuvant radiotherapy (RT) can be applied. However, as this causes morbidity and increases mortality, new Dutch guidelines withhold RT in low-risk patients. The aim of this study is to investigate if early local recurrence and one-year mortality in rectal cancer patients has changed since this more restricting indication for neoadjuvant RT was introduced in 2014. METHODS: This retrospective study included all consecutive patients treated with a mesorectal excision for primary rectal cancer in the Amphia Hospital, the Netherlands, between January 2011 and July 2016...
December 12, 2018: European Journal of Surgical Oncology
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