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European Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/28743374/a-systematic-review-of-generic-and-breast-cancer-specific-life-expectancy-models-in-the-elderly
#1
REVIEW
R Thomas, A Pieri, H Cain
INTRODUCTION: The use of primary endocrine therapy (PET) in managing breast cancer in the elderly has become common practice. Whilst there appears to be no difference in overall survival in comparison with surgery, PET has been found to be inferior in local disease control with a limited duration of efficacy (2-3 years). The International Society of Geriatric Oncology (SIOG) state that PET may be considered in patients with a short life expectancy (<2 years) or considered unfit for surgery...
July 18, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28743373/is-radioiodine-ablation-necessary-for-patients-with-low-risk-papillary-thyroid-carcinoma-and-tumor-4%C3%A2-cm
#2
LETTER
P W Rosario
No abstract text is available yet for this article.
July 18, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28747249/surrogacy-of-progression-free-survival-pfs-for-overall-survival-os-in-esophageal-cancer-trials-with-preoperative-therapy-literature-based-meta-analysis
#3
K Kataoka, K Nakamura, J Mizusawa, K Kato, J Eba, H Katayama, T Shibata, H Fukuda
BACKGROUND: There have been no reports evaluating progression-free survival (PFS) as a surrogate endpoint in resectable esophageal cancer. This study was conducted to evaluate the trial level correlations between PFS and overall survival (OS) in resectable esophageal cancer with preoperative therapy and to explore the potential benefit of PFS as a surrogate endpoint for OS. METHODS: A systematic literature search of randomized trials with preoperative chemotherapy or preoperative chemoradiotherapy for esophageal cancer reported from January 1990 to September 2014 was conducted using PubMed and the Cochrane Library...
July 15, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28734542/improved-survival-after-retrieval-of-12-or-more-regional-lymph-nodes-in-appendiceal-cancer
#4
I Fleischmann, R Warschkow, U Beutner, L Marti, B M Schmied, T Steffen
BACKGROUND: To evaluate the role of regional lymph node (RLN) retrieval on stage migration, overall (OS), and cancer-specific survival (CSS) in appendiceal cancer. METHODS: Between 2004 and 2012, 1046 patients with primary stage I-III carcinoma of the appendix were identified in the Surveillance, Epidemiology and End Results database. The impact of the number of RLN removed on OS and CSS was assessed using joinpoint regression, Cox regression, and propensity score methods...
July 15, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28687431/resectable-invasive-ipmn-versus-sporadic-pancreatic-adenocarcinoma-of-the-head-of-the-pancreas-should-these-two-different-diseases-receive-the-same-treatment-a-matched-comparison-study-of-the-french-surgical-association-afc
#5
P Duconseil, J Périnel, A Autret, M Adham, A Sauvanet, L Chiche, J-Y Mabrut, J-J Tuech, C Mariette, N Régenet, J-M Fabre, P Bachellier, J-R Delpéro, F Paye, O Turrini
PURPOSE: To compare survival and impact of adjuvant chemotherapy in patients who underwent pancreaticoduodenectomy (PD) for invasive intraductal papillary mucinous neoplasm (IIPMN) and sporadic pancreatic ductal adenocarcinoma (PDAC). METHODS: From 2005 to 2012, 240 patients underwent pancreatectomy for IIPMN and 1327 for PDAC. Exclusion criteria included neoadjuvant treatment, pancreatic resection other than PD, vascular resection, carcinoma in situ, or <11 examined lymph nodes...
June 29, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28732670/long-non-coding-rna-neat1-overexpression-is-associated-with-unfavorable-prognosis-in-patients-with-hepatocellular-carcinoma-after-hepatectomy-a-chinese-population-based-study
#6
Z Liu, Q Chang, F Yang, B Liu, H-W Yao, Z-G Bai, C-S Pu, X-M Ma, Y Yang, T-T Wang, W Guo, X-N Zhou, Z-T Zhang
AIM: To identify the association between the expression of lncRNA NEAT1 and clinicopathological characteristics of patients with HCC, and to explore the prognostic significance of lncRNA NEAT1 in predicting prognosis of HCC. METHODS: We retrospectively reviewed 86 patients with HCC (35 female, 51 male) managed in our institution between 2009 and 2014. The expression level of lncRNA NEAT1 was detected by real-time PCR. Prognostic factors were evaluated using Kaplan-Meier curves and Cox proportional hazards models...
June 28, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28688722/retrospective-cohort-analysis-of-neoadjuvant-treatment-and-survival-in-resectable-and-borderline-resectable-pancreatic-ductal-adenocarcinoma-in-a-high-volume-referral-centre
#7
M Itchins, J Arena, C B Nahm, J Rabindran, S Kim, E Gibbs, S Bergamin, T C Chua, A J Gill, R Maher, C Diakos, M Wong, A Mittal, G Hruby, A Kneebone, N Pavlakis, J Samra, S Clarke
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease. Neoadjuvant therapy (NA) with chemotherapy (NAC) and radiotherapy (RT) prior to surgery provides promise. In the absence of prospective data, well annotated clinical data from high-volume units may provide pilot data for randomised trials. METHODS: Medical records from a tertiary hospital in Sydney, Australia, were analysed to identify all patients with resectable or borderline resectable PDAC...
June 28, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28687432/nonsteroidal-anti-inflammatory-drugs-and-the-risk-of-anastomotic-leakage-after-anterior-resection-for-rectal-cancer
#8
D Kverneng Hultberg, E Angenete, M-L Lydrup, J Rutegård, P Matthiessen, M Rutegård
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in colorectal surgery due to their opioid-sparing effect. However, several studies have indicated an increased risk of anastomotic leakage following NSAID treatment, although conflicting results exist. The primary goal of this study was to further examine whether postoperative NSAIDs are independently associated with anastomotic leakage after anterior resection for rectal cancer. METHODS: Patients who underwent anterior resection for rectal cancer during 2007-2013 in 15 different hospitals in three healthcare regions in Sweden were included in the study...
June 28, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28684059/melanoma-patients-disease-specific-knowledge-information-preference-and-appreciation-of-educational-youtube-videos-for-self-inspection
#9
S Damude, J E H M Hoekstra-Weebers, B L van Leeuwen, H J Hoekstra
BACKGROUND: Informing and educating melanoma patients is important for early detection of a recurrence or second primary. This study aimed to investigate Dutch melanoma patients' disease-specific knowledge, and their opinions on information provision and the value of e-Health videos. METHODS: All AJCC stage I-II melanoma patients in follow-up between March 2015 and March 2016 at a single melanoma center were invited to complete 19 online questions, addressing respondents' characteristics, knowledge on melanoma, and opinions on melanoma-specific information received and the educational YouTube videos...
June 24, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28716377/comparison-of-the-7th-and-proposed-8th-editions-of-the-ajcc-uicc-tnm-staging-system-for-esophageal-squamous-cell-carcinoma-underwent-radical-surgery
#10
D Zhang, Y Zheng, Z Wang, Q Huang, X Cao, F Wang, S Liu
BACKGROUND: Recently, the 8th edition of the TNM classification of esophageal cancer has come up. The present study aims to compare the 7th and the proposed 8th edition of the AJCC/UICC TNM staging system for esophageal squamous cell carcinoma (ESCC). METHODS: A total of 1872 ESCC patients who underwent radical surgery with curative intent were analyzed retrospectively. Survival was analyzed using the Kaplan-Meier method, and values were compared using the log-rank test...
June 23, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28688723/focally-positive-margins-in-breast-conserving-surgery-predictors-residual-disease-and-local-recurrence
#11
E L Vos, J Gaal, C Verhoef, K Brouwer, C H M van Deurzen, L B Koppert
BACKGROUND: Re-excision after breast conserving surgery (BCS) for invasive breast cancer (IBC) can be omitted for focally positive margins in the Netherlands, but this guideline is not routinely followed. Focally positive and extensively positive margins have rarely been studied separately and compared to negative margins regarding clinicopathological predictors, residual disease incidence, and local recurrence. METHODS: All females with BCS for Tis-T3, without neo-adjuvant chemotherapy between 2005 and 2014 at one university hospital were included...
June 23, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28669651/frailty-in-major-oncologic-surgery-of-upper-gastrointestinal-tract-how-to-improve-postoperative-outcomes
#12
M Mazzola, C Bertoglio, M Boniardi, C Magistro, P De Martini, P Carnevali, L Morini, G Ferrari
INTRODUCTION: Certain surgical interventions, especially those involving upper GI tract remain challenging, due to high morbidity and mortality rates. The study of frailty in the surgical population has allowed the identification of those patients with a higher risk of poor postoperative outcomes. There remains a lack of evidence regarding the possibility of improving these results through a preoperative holistic management of the patients. The aim of this study is to evaluate whether preoperative treatment, in carefully selected patients, can improve the outcome following surgery...
June 23, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28687430/management-of-the-lateral-neck-in-well-differentiated-thyroid-cancer
#13
REVIEW
J R Cracchiolo, R J Wong
Lateral neck lymph node metastases in well differentiated thyroid cancer are common, ranging from 30% to 60%, with the majority of these foci identifiable only as microscopic deposits. A skilled ultrasound evaluation of the lymph nodes in the lateral neck is recommended for all patients presenting with newly diagnosed thyroid cancer undergoing surgical management. Ultrasound guided fine needle aspiration biopsy may be used to cytologically confirm suspected lateral neck nodal metastases prior to surgery. For patients with large volume nodal disease, extranodal extension, or multiple nodal metastases, computed tomography (CT) scan of the neck with contrast is an important additional imaging modality to accurately localize disease prior to surgery...
June 22, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28666624/neoadjuvant-chemotherapy-or-chemoradiation-for-patients-with-advanced-adenocarcinoma-of-the-oesophagus-a%C3%A2-propensity-score-matched-study
#14
F Favi, E Bollschweiler, F Berlth, P Plum, D Hecheler, H Alakus, R Semrau, E Celik, S P Mönig, U Drebber, A H Hölscher
BACKGROUND: Multimodal therapies are the standard of care for advanced adenocarcinomas of the oesophagus and gastro-oesophageal junction (AEG Types I and II). Only three randomised trials have compared preoperative chemotherapy with and without radiation. The results showed a small benefit for combined chemoradiation. In the meantime, newer therapy protocols are available. AIM: In a propensity-score matched study, we analysed patients with locally advanced AEG type I or II, treated with chemotherapy (FLOT-protocol) or chemoradiation (CROSS-protocol), followed by oesophagectomy, in a single high-volume centre...
June 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28629985/letter-to-editor-intra-operative-assessment-of-excised-breast-tumour-margins-using-clear-edge-imaging-device
#15
LETTER
A S Chekavar, A K Verma, A Agarwal, S Mayilvahanan, T Sundarram, G Johri, S Bothra
No abstract text is available yet for this article.
June 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28655483/the-impact-of-pre-and-post-operative-weight-loss-and-body-mass-index-on-prognosis-in-patients-with-oesophageal-cancer
#16
O Hynes, P Anandavadivelan, J Gossage, A M Johar, J Lagergren, P Lagergren
BACKGROUND: Weight loss is a cardinal symptom of oesophageal cancer and is often continued after surgery. High body mass index (BMI) is a strong risk factor for oesophageal adenocarcinoma. This study aimed to assess the impact of pre- and post-operative weight loss and BMI on long-term mortality after resection for oesophageal cancer. METHODS: This prospective and nationwide cohort study included 390 patients, operated on for oesophageal cancer in Sweden in 2001-2005 with follow-up until 2016, who responded to a questionnaire on weight history 6 months after surgery...
June 15, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28648977/prognostic-relevance-of-lymph-node-status-for-patients-with-ampullary-adenocarcinoma-after-radical-resection-followed-by-adjuvant-treatment
#17
J Kwon, K Kim, E K Chie, B H Kim, J-Y Jang, S W Kim, D-Y Oh, Y-J Bang
PURPOSE: Attempts have been made to revise the nodal stage due to simplicity of current N staging system in ampullary adenocarcinoma. However, because of the disease rarity, there have only been a few studies assessing the prognostic impact of lymph node (LN) parameters. METHODS: We retrospectively analyzed 120 patients who underwent radical resection followed by adjuvant chemoradiotherapy for ampullary adenocarcinoma. The effect of LN parameters (number of total harvest LNs, number of metastatic LN (MLN), lymph node ratio (LNR), and log odds of positive LNs (LODDS)) on overall survival (OS), locoregional relapse-free survival (LRFS) and distant metastasis-free survival were evaluated...
June 15, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28666625/is-intralesional-resection-suitable-for-central-grade-1-chondrosarcoma-a-systematic-review-and-updated-meta-analysis
#18
X Chen, L J Yu, H M Peng, C Jiang, C H Ye, S B Zhu, W W Qian
BACKGROUND: The surgical choice for grade 1 chondrosarcoma has been debated for decades. Intralesional resection can minimize the damage caused by surgery and offer better functional outcome. However, controversy remains about whether it will result in higher rates of local recurrence and metastasis, fewer complications, and better functional outcome compared with resection with wide margin. This systematic review and updated meta-analysis therefore compared intralesional resection and resection with wide margin in terms of local recurrence, metastasis, complications, and functional outcome...
June 14, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28634013/breast-implant-associated-anaplastic-large-cell-lymphoma-impact-and-implications
#19
EDITORIAL
L Wyld, I T Rubio
No abstract text is available yet for this article.
June 12, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28625797/breast-implant-associated-anaplastic-large-cell-lymphoma-from-diagnosis-to-treatment
#20
REVIEW
I Kaartinen, K Sunela, J Alanko, K Hukkinen, M-L Karjalainen-Lindsberg, C Svarvar
Breast lymphomas comprise a rare group of malignant breast tumors. Among these, a new entity has emerged as a potentially under-diagnosed disease. Breast implant-associated anaplastic large cell lymphoma (BI-ALCL) most often manifests as a late periprosthetic effusion between 1 and 10 years after the implantation of silicone or saline-filled breast prostheses. BI-ALCL is an anaplastic lymphoma kinase-negative T-cell lymphoma that has a distinctively different clinical course than other breast lymphomas or ALCLs...
June 7, 2017: European Journal of Surgical Oncology
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