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REVIEW
Bowen Wang, Xingyue Ma, Xiao Zhang, Xiaoyan Zhang, Shuai Guan, Tiepeng Xiao, Xiangjun Li
To address the limitations of conventional sentinel lymph node biopsy (SLNB), a novel hybrid tracer (indocyanine green [ICG]-99m Tc-nanocolloid) has been developed. This meta-analysis aimed to compare the differences between the novel hybrid tracer and conventional methods using ICG or radioisotope (RI) for SLNB in head and neck malignancies. This study was registered in the International Prospective Register of Systematic Reviews (CRD42023409127). PubMed, Embase, Web of Science, and the Cochrane Library were systematically searched...
April 20, 2024: European Journal of Surgical Oncology
#2
JOURNAL ARTICLE
T M Gilbert, L Randle, M Quinn, O McGreevy, L O'leary, R Young, R Diaz-Neito, R P Jones, B Greenhalf, C Goldring, S Fenwick, H Malik, D H Palmer
Cholangiocarcinoma (CCA) remains a devastating malignancy and a significant challenge to treat. The majority of CCA patients are diagnosed at an advanced stage, making the disease incurable in most cases. The advent of high-throughput genetic sequencing has significantly improved our understanding of the molecular biology underpinning cancer. The identification of 'druggable' genetic aberrations and the development of novel targeted therapies against them is opening up new treatment strategies. Currently, 3 targeted therapies are approved for use in CCA; Ivosidenib in patients with IDH1 mutations and Infigratinib/Pemigatinib in those with FGFR2 fusions...
April 17, 2024: European Journal of Surgical Oncology
#3
REVIEW
Jacopo Crippa, Carmelo Magistro, Isacco Montroni, Giacomo Borroni, Antonio Ziccarelli, Antonino Spinelli, Giulio Maria Mari
Research in surgery faces intrinsic difficulties such as the lack of reproducibility of surgical operations, self-referring surgeons, decentralized data. Establishing a community of qualified researchers across surgeons is crucial. Clinical networks have been proposed as solutions to many challenges in surgical research, yet their implementation remains uncommon, especially for surgical trialists. The extent of literature produced by networks remains unclear, but fostering such collaborations could enhance the overall quality of surgical research...
April 17, 2024: European Journal of Surgical Oncology
#4
JOURNAL ARTICLE
Shady A Saleem, Fatma El-Zahraa A Mustafa, Hanan H Abd-Elhafeez, Gilan A Ahmed
Congenital tumors are rare, and malignant congenital tumors are uncommon. Benign tu,mors might be life-threatening, depending on the location and size of the tumor. Different factors affect congenital tumors, such as maternal and placental hormones and environmental factors such as drugs, radiation, and infection. Developing fetal imaging methods and continuous follow-up during pregnancy are important factors in congenital tumor prognosis. Ultrasound is the most common method used for fetal evaluation. The complementary evaluation method is MRI...
April 16, 2024: European Journal of Surgical Oncology
#5
JOURNAL ARTICLE
Akiko Ogiya, Kiyomi Kimura, Takayuki Ueno, Takuji Iwase, Shinji Ohno
PURPOSE: To clarify how body mass index (BMI) affects the development and temporal trend of breast cancer-related lymphedema (BCRL). METHODS: This is a prospective study in which patients with operable breast cancer were registered in a single institute between November 2009 and July 2010. The incidence of lymphedema at 1, 3, and 5 years after surgery was assessed according to BMI, and the trend of newly developed BCRL was examined. Obesity was defined as BMI ≥25 in accordance with the Japan Society for the Study of Obesity...
April 16, 2024: European Journal of Surgical Oncology
#6
LETTER
Hasnain Wajeeh Us Saqib, Ali Abdullah, Abdul Majid
No abstract text is available yet for this article.
April 16, 2024: European Journal of Surgical Oncology
#7
JOURNAL ARTICLE
Manish S Bhandare, Kaival K Gundavda, Raghav Yelamanchi, Amit Chopde, Swati Batra, Manjushree Kolhe, Anant Ramaswamy, Vikas Ostwal, Kedar Deodhar, Vikram Chaudhari, Shailesh V Shrikhande
BACKGROUND: Advances in perioperative chemotherapy have improved outcomes in patients with gastric cancers (GC). This strategy leads to tumour downstaging and may result in a pathologic complete response (pCR). The study aimed to evaluate the predictors of pCR and determine the impact of pCR on long-term survival. METHODS: At the Department of Gastrointestinal and HPB Oncology at the Tata Memorial Centre, Mumbai, 1001 consecutive patients with locally advanced GCs undergoing radical resection following neoadjuvant chemotherapy from January 2005 to June 2022 were included...
April 16, 2024: European Journal of Surgical Oncology
#8
JOURNAL ARTICLE
Ping-Chung Tsai, Yen-Chiang Tseng, Ying-Che Ting, Chien-Sheng Huang, Wen-Hu Hsu, En-Kuei Tang, Han-Shui Hsu
BACKGROUD: The standard resection for early-stage thymoma is total thymectomy and complete tumour excision with or without myasthenia gravis but the optimal surgery mode for patients with early-stage non-myasthenic thymoma is debatable. This study analysed the oncological outcomes for non-myasthenic patients with early-stage thymoma treated by thymectomy or limited resection in the long term. METHODS: Patients who had resections of thymic neoplasms at Taipei Veteran General Hospital, Taiwan between December 1997 and March 2013 were recruited, exclusive of those combined clinical evidence of myasthenia gravis were reviewed...
April 16, 2024: European Journal of Surgical Oncology
#9
JOURNAL ARTICLE
C Buchalet, P Loap, S Losa, E Laas, T Gaillard, F Lecuru, C Malhaire, V Huchet, A De La Rochefordiere, A Labib, M Kissel
OBJECTIVE: The treatment of early-stage cervical cancer (CC) is primarily based on surgery. Adjuvant (chemo)radiotherapy can be necessary in presence of risk factors for relapse (tumor size, deep stromal invasion, lymphovascular space invasion (LVSI), positive margins, parametrial or lymph node involvement), increasing the risk of treatment toxicity. Preoperative brachytherapy can reduce tumor extension before surgery, potentially limiting the need for adjuvant radiotherapy. This study reports long-term clinical outcomes on efficacy and toxicity of preoperative pulse-dose-rate (PDR) brachytherapy in early-stage CC...
April 16, 2024: European Journal of Surgical Oncology
#10
JOURNAL ARTICLE
Marta Viscuso, Roel L J Verhoeven, Stephan E P Kops, Gerjon Hannink, Rocco Trisolini, Erik H F M van der Heijden
BACKGROUND: Cone beam CT based Navigation Bronchoscopy (CBCT-NB) has predominantly been investigated as a diagnostic tool in (suspected) primary lung cancers. Small metastatic lesions are clinically considered more challenging to diagnose, but no study has explored the yield of navigation bronchoscopy in patients with pulmonary metastatic lesions (ML) compared to primary lung cancers (PL), correcting for known lesion characteristics affecting diagnostic yield. MATERIALS AND METHODS: This is a single-center, retrospective, propensity score-matched case-control study...
April 15, 2024: European Journal of Surgical Oncology
#11
JOURNAL ARTICLE
Jun Yang, Zixuan Fu, Weiwei Sheng, Zhihao Huang, Jiandong Peng, Pengcheng Zhou, Jianghui Xiong, Rongshou Wu, Wenjun Liao, Linquan Wu, Enliang Li
BACKGROUND: The optimal surgical approach for Bismuth II hilar cholangiocarcinoma (HCCA) remains controversial. This study compared perioperative and oncological outcomes between minor and major hepatectomy. MATERIALS AND METHODS: One hundred and seventeen patients with Bismuth II HCCA who underwent hepatectomy and cholangiojejunostomy between January 2018 and December 2022 were retrospectively investigated. Propensity score matching created a cohort of 62 patients who underwent minor (n = 31) or major (n = 31) hepatectomy...
April 12, 2024: European Journal of Surgical Oncology
#12
JOURNAL ARTICLE
Carla Apostolova, Amina Ferroum, Basmah Alhassan, Ipshita Prakash, Mark Basik, Jean Francois Boileau, Karyne Martel, Sarkis Meterissian, Victor Villareal Corpuz, Nora Wong, William D Foulkes, Stephanie M Wong
INTRODUCTION: The impact of timing of genetic testing on uptake of risk reducing mastectomy (RRM) in affected female BRCA1/2 or PALB2 carriers remains an area of evolving interest, particularly with the introduction of mainstream genetic testing initiatives. METHODS: Women with stage I-III breast cancer and a confirmed germline pathogenic variant in BRCA1/2 or PALB2 between 2000 and 2023 were identified from an institutional genetics database. Uptake of RRM was evaluated according to disclosure of genetic testing results before or after index surgery for a first diagnosis of breast cancer...
April 12, 2024: European Journal of Surgical Oncology
#13
JOURNAL ARTICLE
Víctor Lago, Manel Montesinos Albert, Marta Arnaez Cruz, Rafael Alberto Guijarro Campillo, Pablo Padilla-Iserte, Luis Matute, Marta Gurrea, Blas Flor, Santiago Domingo
BACKGROUND: The incidence of anastomotic leak after colorectal anastomosis in ovarian cancer has been reported to be much lower than that in colorectal cancer patients. Regarding the use of protective manoeuvres (diverting ileostomy) as suggested by clinical guidelines, the goal should be the implementation of a restrictive stoma policy for ovarian cancer patients, given the low rate of anastomotic leakage in this population. MATERIAL AND METHODS: Patients who underwent cytoreduction surgery in a single centre (University Hospital La Fe, Valencia Spain) due to ovarian cancer between January 2010 and June 2023 were classified according to two groups: a non-restrictive stoma policy group (Group A) and a restrictive stoma policy group (Group B)...
April 11, 2024: European Journal of Surgical Oncology
#14
JOURNAL ARTICLE
P Matos da Costa, Cláudia Antunes, Patrícia Lages, Jéssica Rodrigues, Mariana Peyroteo, Susana Onofre, Lúcio Lara Santos
Expanding loco-regional nodes harvesting is expected to increase survival. This improvement may be associated to stage migration (SM). However, the great bulk of harvested lymph nodes observed in large dissections is negative. M&M: 830 patients who received R0 gastrectomy for adenocarcinoma were included. pN+ patients with <26 nodes (n = 209) were included for a simulation to "offer 26 nodes" - SM (proportional and exponential based) was simulated and analysed through machine learning algorithms...
April 11, 2024: European Journal of Surgical Oncology
#15
REVIEW
Lu Zhou, Zhengyang Zhang, Ling Wang
INTRODUCTION: There has been a lack of research comparing the efficacy of various treatments for low anterior resection syndrome (LARS). METHODS: We conducted a comprehensive search across six electronic databases and a paired meta-analysis was undertaken to assess the effectiveness of the interventions. Furthermore, a network meta-analysis was utilized to compare the efficacy of different treatments for LARS. RESULTS: This study encompassed nine randomized controlled trials, involving a total of 450 patients...
April 10, 2024: European Journal of Surgical Oncology
#16
JOURNAL ARTICLE
Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Xiangdong Cheng
OBJECTIVE: The geriatric nutritional risk index (GNRI) is a novel nutrition-related indicator designed to predict the risk of clinical outcomes in various cancers. The clinical significance of risk assessment, therapeutic response, and prognostic prediction of GNRI in esophageal squamous cell carcinoma (ESCC) receiving neoadjuvant immunochemotherapy (NICT), a hot point of treatment these days, have not been documented in any research. METHODS: Two hundred and twenty-four cases with ESCC who underwent radical resection after NICT were retrospectively recruited...
April 8, 2024: European Journal of Surgical Oncology
#17
JOURNAL ARTICLE
Jin-du Zhao, Xian-Ying Lu, Tian-Ping Chen, Xian-Lun Duan, Wei Zuo, Kai Sai, Li-Ran Zhu, Qun Gao
PURPOSE: The aim of this study was to develop a nomogram specially for predicting overall survival (OS) for Chinese patients with neuroblastoma (NB). METHODS: Patients with pathologically confirmed NB who were newly diagnosed and received treatments at our hospital from October 2013 to October 2021 were retrospectively reviewed. The nomogram for OS were built based on Cox regression analysis. The validation of the prognostic model was evaluated by concordance index (C-index), calibration curves, and decision curve analyses (DCAs)...
April 6, 2024: European Journal of Surgical Oncology
#18
JOURNAL ARTICLE
Michelle V Dietz, Gerjon Hannink, Ibrahim Said, Femke A van der Zant, Vincent C J van de Vlasakker, Alexandra R M Brandt-Kerkhof, Cornelis Verhoef, Andreas J A Bremers, Johannes H W de Wilt, Patrick H J Hemmer, Ignace H J T de Hingh, Philip R de Reuver, Eva V E Madsen
INTRODUCTION: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival outcomes for selected patients with colorectal peritoneal metastases (PM), but recurrence rates are high. The aim of this study was to develop a tool to predict recurrence in patients with colorectal PM that undergo CRS-HIPEC. MATERIALS AND METHODS: For this retrospective cohort study, data of patients that underwent CRS-HIPEC for colorectal PM from four Dutch HIPEC centers were used...
April 4, 2024: European Journal of Surgical Oncology
#19
JOURNAL ARTICLE
Jonathan Spoor, Eva Heeling, Romy C Collewijn, Iris M C van der Ploeg, Marije J Hoornweg, Nicola Russell, Jose G van den Berg, Marie-Jeanne F T D Vrancken Peeters, Frederieke H van Duijnhoven
BACKGROUND: Nipple preservation contributes to aesthetic outcome and quality of life in women undergoing Skin-Sparing Mastectomy (SSM) with immediate breast reconstruction for the treatment of breast cancer. Intraoperative Frozen Section (IFS) has been advocated to facilitate conversion from Nipple-Sparing Mastectomy (NSM) to SSM in cases with positive subareolar margins. This study investigated the application of IFS at our comprehensive cancer centre. METHODS: In this single-centre retrospective study, for all patients who underwent therapeutic NSM with IFS from 2000 to 2021 pathological reports, patient- and tumour characteristics were retrieved...
April 3, 2024: European Journal of Surgical Oncology
#20
JOURNAL ARTICLE
Tijs J Hoogteijling, Mohammad Abu Hilal, Giuseppe Zimmitti, Davit L Aghayan, Andrew G R Wu, Federica Cipriani, Salvatore Gruttadauria, Olivier Scatton, Tran Cong Duy Long, Paulo Herman, Marco V Marino, Vincenzo Mazzaferro, Adrian K H Chiow, Iswanto Sucandy, Arpad Ivanecz, Sung Hoon Choi, Jae Hoon Lee, Mikel Gastaca, Marco Vivarelli, Felice Giuliante, Andrea Ruzzenente, Chee Chien Yong, Mengqiu Yin, Constantino Fondevila, Mikhail Efanov, Zenichi Morise, Fabrizio Di Benedetto, Raffaele Brustia, Raffaele Dalla Valle, Ugo Boggi, David Geller, Andrea Belli, Riccardo Memeo, Alejandro Mejia, James O Park, Fernando Rotellar, Gi Hong Choi, Ricardo Robles-Campos, Xiaoying Wang, Robert P Sutcliffe, Johann Pratschke, Chung-Ngai Tang, Charing C N Chong, Mathieu D'Hondt, Kazuteru Monden, Santiago Lopez-Ben, T Peter Kingham, Alessandro Ferrero, Giuseppe Maria Ettorre, Daniel Cherqui, Xiao Liang, Olivier Soubrane, Go Wakabayashi, Roberto I Troisi, Ho Seong Han, Tan To Cheung, Atsushi Sugioka, Safi Dokmak, Kuo Hsin Chen, Rong Liu, David Fuks, Wanguang Zhang, Luca Aldrighetti, Bjørn Edwin, Brian K P Goh
BACKGROUND: In the last three decades, minimally invasive liver resection has been replacing conventional open approach in liver surgery. More recently, developments in neoadjuvant chemotherapy have led to increased multidisciplinary management of colorectal liver metastases with both medical and surgical treatment modalities. However, the impact of neoadjuvant chemotherapy on the surgical outcomes of minimally invasive liver resections remains poorly understood. METHODS: A multicenter, international, database of 4998 minimally invasive minor hepatectomy for colorectal liver metastases was used to compare surgical outcomes in patients who received neoadjuvant chemotherapy with surgery alone...
April 2, 2024: European Journal of Surgical Oncology
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