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Digestive Surgery

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https://www.readbyqxmd.com/read/28817822/predictors-of-postoperative-non-chylous-massive-discharge-after-pancreaticoduodenectomy-for-pancreatic-ductal-adenocarcinoma
#1
Kyoji Ito, Yoshikuni Kawaguchi, Yoshihiro Sakamoto, Junichi Arita, Kiyoshi Hasegawa, Norihiro Kokudo
BACKGROUND: Pancreaticoduodenectomy (PD) is performed for pancreatic ductal adenocarcinoma (PDA) located at the pancreas head/body. Non-chylous massive discharge after PD is frequently encountered and can cause a vicious cycle of complications associated with severe dehydration and protein loss. METHODS: From August 2008 to June 2015, 102 patients who underwent PD for PDA were retrospectively reviewed. High non-chylous discharge was defined as postoperative daily serous discharge exceeding 10 mL/kg...
August 18, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28810253/outcomes-of-self-expanding-metal-stents-in-malignant-colonic-obstruction-are-independent-of-location-or-length-of-the-stenosis-results-of-a-retrospective-single-center-series
#2
Paul K Schoonbeek, Pim Genzel, Eline H van den Berg, O Aart van Dobbenburgh, Frank Ter Borg
AIM: To evaluate the length and location of stenosis in the colon as predictors of technical and clinical outcomes of stent placement in patients presenting with obstructive colorectal cancer. METHODS: A prospective single-center cohort study of patients treated with a colonic stent for malignant obstruction, regardless of stenosis length or location. Stenosis length was assessed globally on the appropriate CT slice as well as by 3D CT reconstruction. We analyzed whether outcomes were different in patients with a right sided-tumor and/or a stenosis >4 cm long...
August 16, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28810252/the-impact-of-the-hepatitis-b-core-antibody-status-on-recurrence-in-patients-with-non-b-non-c-hepatocellular-carcinoma-after-curative-surgery
#3
Yukiyasu Okamura, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhiko Uesaka
BACKGROUND: The serum antibody to hepatitis B core antigen (HBcAb) is considered a risk factor of liver carcinogenesis. This study aimed to reveal whether HBcAb status is a prognostic factor after hepatectomy is performed for treating hepatocellular carcinoma (HCC). METHODS: This retrospective study enrolled 272 patients who underwent hepatectomy as the initial treatment for HCC and who were followed up over 5 years after surgery. The types of HCC were classified into the following 3 types according to the hepatitis virus infection status and the patients without hepatitis virus infection non-B non-C HCC (NBNC-HCC) were further classified into 2 groups...
August 16, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28787731/the-impact-of-serosal-invasion-on-prognosis-after-curative-hepatectomy-for-hepatocellular-carcinoma-invasion-to-adjacent-organs-and-rupture-of-tumor-were-crucial-tumor-related-prognostic-factors-needed-for-survival
#4
Yoshiyasu Kato, Yukiyasu Okamura, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhiko Uesaka
BACKGROUND/AIMS: Several tumor factors seem to be related to the hepatocellular carcinoma (HCC) prognosis, but they are not definitive, except for major vascular invasion. We analyzed the impact of serosal invasion, which is histologically classified into four groups according to the definition of the Liver Cancer Study Group of Japan - S0: no tumor invasion of serosa, S1: tumor invasion of serosa, S2: tumor invasion of adjacent organs, S3: tumor rupture with intraperitoneal bleeding...
August 9, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28768258/septic-complications-after-resection-for-middle-or-low-rectal-cancer-role-of-gut-barrier-function-and-inflammatory-serum-markers
#5
Mario Schietroma, Beatrice Pessia, Sara Colozzi, Francesco Carlei, Marco Clementi, Gianfranco Amicucci, Stefano Guadagni
BACKGROUND: The focus of this study was to understand the relationship between the failure of gut barrier function, inflammatory markers and septic complications after resection for extraperitoneal rectal cancer. METHODS: One hundred seven patients were enrolled into this prospective observational study and underwent open colorectal resection for extraperitoneal cancer. All patients underwent an assessment of intestinal permeability (L/M ratio), endotoxemia, interleukin-1β (IL-1β), interleukin-6 (IL-6), C-reactive protein (CRP) and elastase levels before surgery and on postoperative days 1, 3, and 7...
August 3, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28768254/intracorporeal-versus-extracorporeal-anastomoses-following-laparoscopic-right-colectomy-in-obese-patients-a-case-matched-study
#6
Andrea Vignali, Ugo Elmore, Maria Lemma, Giovanni Guarnieri, Giovanni Radaelli, Riccardo Rosati
BACKGROUND/AIMS: To compare short- and long-term outcomes of intracorporeal anastomosis (IA) versus extracorporeal anastomosis (EA) in obese (body mass index >30 kg/m2) patients. PATIENTS AND METHODS: Sixty-four consecutive obese patients who underwent laparoscopic (LPS) right colectomy with IA were matched with 64 patients who underwent LPS right colectomy with EA. Intraoperative variables, short-term outcomes, readmission rates, and morbidity and mortality rates were analyzed along with long-term outcomes...
August 3, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28704814/acalculous-cholecystitis-is-an-elective-interval-cholecystectomy-necessary
#7
Syed H Abbas, Mudassar A Ghazanfar, Alex N Gordon-Weeks, Srikanth R Reddy, Zahir Soonawalla, Michael A Silva
BACKGROUND: Acute acalculous cholecystitis (AAC) accounts for 5-10% of cases of acute cholecystitis. The advantage of interval cholecystectomy for patients with AAC is unclear. Therefore, a retrospective analysis of patients diagnosed with AAC at our institution was performed over a 5-year period. METHODS: Patients were identified via hospital coding using the keywords "acalculous cholecystitis, cholecystostomy and gall bladder perforation." Follow-up data was obtained by performing a retrospective review of the patients' hospital records...
July 14, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28700995/extended-pancreatectomy-does-it-have-a-role-in-the-contemporary-management-of-pancreatic-adenocarcinoma
#8
Joerg Kaiser, Thilo Hackert, Markus W Büchler
BACKGROUND: Pancreatic cancer is a low-incident but highly mortal disease. Surgery is still the preferred treatment option for resectable pancreatic cancer as it offers the only realistic chance for cure. As many patients present with locally advanced disease, which is generally considered as not amenable to surgical treatment, it is important to know the limits of surgical therapy in this disease. METHODS: In this review, the indication and outcomes of extended pancreatectomies as well as the alternative treatment options for locally advanced pancreatic cancer are described...
July 13, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28697493/does-the-margin-matter-in-esophageal-cancer
#9
Karl-Frederick Karstens, Jakob R Izbicki, Matthias Reeh
BACKGROUND: The prognostic impact of circumferential resection margin (CRM) involvement in resected esophageal cancer (EC) is controversial discussed. The College of American Pathologists (CAP) and the Royal College of Pathologists (RCP) provide 2 different definitions of CRM involvement. The aim of this systematic review was to evaluate the clinical significance of CRM involvement on patients' survival following esophagectomy due to EC. METHODS: PubMed, Science Direct, and Google scholar were searched for studies analyzing the clinical impact of CRM in EC...
July 12, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28675905/do-we-need-to-add-postoperative-radiotherapy-in-patients-undergoing-trimodality-therapy-for-esophageal-squamous-cell-carcinoma-with-positive-lymph-nodes-disease
#10
Pei-Ming Huang, Feng-Ming Hsu, Chia-Chi Lin, Chin-Hung Hsu, Jason Chia-Hsien Cheng, Jang-Ming Lee
BACKGROUND: The role of adjuvant radiotherapy for positive lymph nodes (LN) in patients with esophageal cancer who received neoadjuvant concurrent chemoradiotherapy (CCRT) is not well established. This study is aimed at determining the impact of positive LN and the survival benefit of postoperative radiotherapy (PORT) after CCRT plus surgery on esophageal cancer patients. METHODS: Seventy patients with positive LN after neoadjuvant CCRT followed by esophagectomy were enrolled in the study...
July 4, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28668951/the-relationship-between-age-common-bile-duct-diameter-and-diagnostic-probability-in-suspected-choledocholithiasis
#11
Efstathios Karamanos, Kenji Inaba, Regan J Berg, Shelby Resnick, Obi Okoye, Sophoclis Alexopoulos, Konstantinos Chouliaras, Demetrios Demetriades
BACKGROUND: Aging has been associated with increasing common bile duct (CBD) diameter and reported as independently predictive of the likelihood of choledocolithiasis. These associations are controversial with uncertain diagnostic utility in patients presenting with symptomatic disease. The current study examined the relationship between age, CBD size, and the diagnostic probability of choledocolithiasis. METHODS: Symptomatic patients undergoing evaluation for suspected choledocolithiasis from January 2008 to February 2011 were reviewed...
July 1, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28662525/colonic-histological-criteria-predict-development-of-pouchitis-after-ileal-pouch-anal-anastomosis-for-patients-with-ulcerative-colitis
#12
Toshimitsu Araki, Kiyoshi Hashimoto, Yoshiki Okita, Hiroyuki Fujikawa, Satoru Kondo, Minako Kobayashi, Masaki Ohi, Yuji Toiyama, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
BACKGROUND/AIMS: Pouchitis is one of the main complications after ileal pouch-anal anastomosis in patients with ulcerative colitis. The aim of this study was to determine whether the use of colonic histological criteria can predict the development of pouchitis. METHODOLOGY: We retrospectively reviewed 147 patients' clinical data and performed a histological evaluation of the resected total colon using Tanaka's criteria, which comprise the following 6 factors: ulceration (H1), crypt abscesses (H2), degree of mononuclear cell infiltration (MNCI) (H3), segmental distribution of MNCI (H4), eosinophil infiltration (H5), and extent of disease of resected colon (H6)...
June 30, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28654927/acute-diverticulitis-and-subsequent-colonoscopy-instigating-an-old-discussion
#13
Tiago Cúrdia Gonçalves, Mara Barbosa, Carla Marinho, José Cotter
No abstract text is available yet for this article.
June 28, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28647737/trends-in-the-management-of-acute-appendicitis-in-a-single-center-quality-register-cohort-of-5-614-patients
#14
Martin J A Dahlberg, Emil H A Pieniowski, Lennart Å S Boström
Acute appendicitis is one of the most common reasons for emergency surgery. At Stockholm South General Hospital, information on all patients - 15 years or older - undergoing surgery for acute appendicitis is included in a quality register. Data on surgical method, preoperative imaging, hospital stay, intraoperative findings, and 30-day complications were recorded for each patient. From January 2004 to December 2014, 5,614 consecutive patients were registered. The percentage of patients examined with preoperative imaging increased from 30% in 2004 to 93% in 2014...
June 24, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28637034/recovery-of-food-intake-after-gastrectomy-for-gastric-cancer-based-on-a-large-scale-gastric-cancer-cohort
#15
Bang Wool Eom, Jeongseon Kim, Deok Hee Kim, Young-Il Kim, Hong Man Yoon, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi, Young-Woo Kim, Byung-Ho Nam, Keun Won Ryu
BACKGROUND: This study was aimed at evaluating the food intake and nutritional status of patients who underwent gastrectomy for gastric cancer based on a large-scale gastric cancer cohort. METHODS: An observational prospective cohort study for gastric cancer has been conducted since 2010. From the cohort data, we selected the data for patients who completed at least 2 days of 3-day diet diaries and who underwent subtotal gastrectomy (STG) or total gastrectomy (TG)...
June 22, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28637039/different-impacts-of-preoperative-radiotherapy-and-chemoradiotherapy-on-oncological-outcomes-in-patients-with-stages-ii-and-iii-lower-rectal-cancer-a-propensity-score-analysis
#16
Hirotoshi Takiyama, Kazushige Kawai, Soichiro Ishihara, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Keisuke Hata, Hiroaki Nozawa, Teppei Morikawa, Toshiaki Watanabe
BACKGROUND/AIMS: The neoadjuvant therapy for locally advanced rectal cancer has been changed from radiotherapy (RT) to chemoradiotherapy (CRT). This study is aimed at evaluating the benefit of CRT in patients with stage II or III lower rectal cancer, with regard to the impact on recurrence. METHODS: A total of 474 patients with clinical stage II or III lower rectal cancer who received either preoperative RT (n = 221) or CRT (n = 253) followed by total mesorectal excision were identified from our institutional database...
June 21, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28637037/surgical-site-infection-after-hepatectomy-for-hepatocellular-carcinoma
#17
Chikara Shirata, Kiyoshi Hasegawa, Takashi Kokudo, Junichi Arita, Nobuhisa Akamatsu, Junichi Kaneko, Yoshihiro Sakamoto, Masatoshi Makuuchi, Norihiro Kokudo
AIMS: To clarify the clinical impact, risk factors, and preventive methods for surgical site infection (SSI) after hepatectomy for hepatocellular carcinoma (HCC). METHODS: We included 879 consecutive patients who underwent hepatectomy for HCC between 2002 and 2011. Univariate and multivariate analyses were conducted to identify the risk factors for incisional and organ/space SSIs. ORs and 95% CIs are reported. RESULTS: The incidences of incisional and organ/space SSIs were 24 (2...
June 21, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28564643/prevent-pancreatic-fistula-after-pancreatoduodenectomy-possible-role-of-ultrasound-elastography
#18
Mirko D'Onofrio, Giulia Tremolada, Riccardo De Robertis, Stefano Crosara, Valentina Ciaravino, Nicolò Cardobi, Giovanni Marchegiani, Alessandra Pulvirenti, Valentina Allegrini, Roberto Salvia, Claudio Bassi, Roberto Pozzi Mucelli
BACKGROUND: The purpose of the study is to evaluate the utility of acoustic radiation force impulse (ARFI) on pancreatic tissue as a preoperative predictor of postoperative pancreatic fistula (POPF). Studied patients underwent exclusively to pancreaticoduodenectomy (PD) surgery. METHODS: Shear wave velocity of pancreas was measured using ARFI in 71 patients scheduled for PD. An intraoperative pancreas palpation was made by surgeons. A postoperative clinical evaluation to detect occurrence of POPF was performed...
June 1, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28554185/clinical-challenges-in-upper-gastrointestinal-malignancies-after-bariatric-surgery
#19
Win Hou W Tse, Hidde M Kroon, J Jan B van Lanschot
BACKGROUND/AIMS: The incidence of morbid obesity has exponentially increased over the last decades. Bariatric surgery (BS) has been proven effective in inducing weight loss and resolving comorbidities associated with morbid obesity. However, BS can also lead to major diagnostic and treatment challenges in patients who develop upper gastrointestinal malignancies. It is important to create awareness of this rising problem. METHODS: Relevant literature was searched in PubMed...
May 30, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28554183/a-pilot-trial-of-s-1-and-paclitaxel-in-unresectable-or-postoperative-recurrent-esophageal-squamous-cell-carcinoma-pretreated-by-fluorouracil-cisplatin-and-docetaxel-chemotherapy
#20
Yasuaki Nakajima, Kenro Kawada, Yutaka Tokairin, Akihiro Hoshino, Takuya Okada, Tatsuyuki Kawano
BACKGROUND/AIMS: This study documents the clinical efficacy and toxicity of S-1 and paclitaxel (S1/PTX) in patients with unresectable or postoperative recurrent esophageal squamous cell carcinoma (ESCC) who had been previously treated with fluorouracil (5FU), cisplatin, and docetaxel. METHODS: Twenty-eight ESCC patients treated using S1/PTX at our institute since 2010 were enrolled in this study. S1 was administered orally at a dose of 80 mg/m2/day from days 1 to 14, and PTX was administered intravenously on days 1 and 8 at a dose of 80-100 mg/m2...
May 30, 2017: Digestive Surgery
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