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Digestive Surgery

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https://www.readbyqxmd.com/read/28494458/improvement-of-anal-function-by-adipose-derived-stem-cell-sheets
#1
Yusuke Inoue, Fumihiko Fujita, Izumi Yamaguchi, Hiroko Kinoe, Daisuke Kawahara, Yusuke Sakai, Tamotsu Kuroki, Susumu Eguchi
AIM: One of the most troublesome complications of anal preserving surgery is anal sphincter dysfunction. The aim of this study was to evaluate functional recovery after implantation of adipose-derived stem cell (ADSC) sheets, novel biotechnology, for an anal sphincter resection animal model. METHODS: Eighteen female Sprague-Dawley rats underwent removal of the nearest half of the internal and external anal sphincter muscle. Nine rats received transplantation with ADSC sheets to the resected area while the remaining rats received no transplantation...
May 12, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28494443/short-term-clinical-and-oncological-outcomes-after-single-incision-plus-one-port-laparoscopic-anterior-resection-for-rectal-cancer
#2
Yasumitsu Hirano, Masakazu Hattori, Kenji Douden, Mari Shimada, Yasuo Hashizume
AIM: In the past, we developed and reported single-incision plus one port laparoscopic anterior resection (SILS + 1-AR) of the rectum. In this study, we reviewed our experiences with 141 consecutive patients admitted in a community hospital for undergoing SILS + 1-AR for rectal cancer and evaluated the short-term clinical and oncological outcomes. METHODS: A lap protector (LP) was inserted through a 2.5 cm transumbilical incision; an EZ-access was mounted to the LP and three 5-mm ports were placed...
May 12, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28494442/efficacy-of-hyaluronic-acid-carboxymethyl-cellulose-based-bioresorbable-membranes-in-reducing-perihepatic-adhesion-formation-a-prospective-cohort-study
#3
Atsushi Shimizu, Kiyoshi Hasegawa, Koichi Masuda, Kiyohiko Omichi, Akinori Miyata, Norihiro Kokudo
BACKGROUND: Perihepatic adhesions induced by hepatectomy make the subsequent repeat hepatectomy technically demanding. The aim of this study was to verify the effect of hyaluronic acid/carboxymethyl cellulose-based bioresorbable membrane (HA membrane) in preventing posthepatectomy adhesion formation by focusing on the ease of the adhesiolysis in subsequent hepatectomy for recurrent tumors. METHODS: A total of 201 patients who underwent hepatectomy using HA membrane were prospectively followed-up for 3 years...
May 12, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28490009/clinicopathologic-study-of-biliary-intraepithelial-neoplasia-in-cholangiocarcinoma
#4
Hyo Jung Kim, Jae Seon Kim, Baek Hee Kim, Young-Tae Bak
BACKGROUNDS AND AIMS: Biliary intraepithelial neoplasia (BilIN) is a precursor of cholangiocarcinoma (CC) and it has been associated with several chronic inflammatory conditions. This study aimed to elucidate the prevalence of BilIN in CC and its clinicopathological significance. METHODS: Medical records of 193 patients with histologically confirmed CC were analyzed. We reviewed the pathology findings of 48 patients who underwent curative surgery for CC. RESULTS: Of the 48 patients analyzed, 34 and 14 patients had extrahepatic and intrahepatic CC respectively...
May 11, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28486220/risk-factors-for-early-postoperative-small-bowel-obstruction-after-elective-colon-cancer-surgery-an-observational-study-of-1-244-consecutive-patients
#5
Xiao-Jie Wang, Pan Chi, Hui-Ming Lin, Xing-Rong Lu, Ying Huang, Zong-Bin Xu, Sheng-Hui Huang, Yan-Wu Sun, Dao-Xiong Ye
BACKGROUND: Early postoperative small bowel obstruction (EPSBO) is a common complication following colon cancer surgery. EPSBO is associated with increased hospital stays, mortality rates, and healthcare costs. The purpose of this study was to identify risk factors for EPSBO following elective colon cancer surgery. STUDY DESIGN: We retrospectively reviewed the clinicopathological variables of 1,244 patients with colon cancer who underwent partial colectomy from January 2000 to December 2014...
May 10, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28482348/prolonged-neoadjuvant-therapy-for-locally-advanced-pancreatic-cancer
#6
Hidetoshi Eguchi, Daisaku Yamada, Yoshifumi Iwagami, Kunihito Gotoh, Koichi Kawamoto, Hiroshi Wada, Tadafumi Asaoka, Takehiro Noda, Yutaka Takeda, Masahiro Tanemura, Daisuke Sakai, Taroh Satoh, Toshihiro Kudo, Fumiaki Isohashi, Masaki Mori, Yuichiro Doki
PURPOSE: The purpose of this study was to investigate if prolonged neoadjuvant therapy, for locally advanced pancreatic cancer could be used to identify those patients who could benefit from resection surgery. METHODS: Thirty-four patients with locally advanced pancreatic cancer invading the adjacent major arteries underwent chemoradiotherapy, followed by 6 months of systemic chemotherapy, unless their tumor was already resectable. After this combination treatment, surgical resection was performed on those patients with tumors judged to be at least borderline resectable...
May 9, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28467983/combined-antrectomy-reduces-the-incidence-of-delayed-gastric-emptying-after-pancreatoduodenectomy
#7
Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Teiichi Sugiura, Yukiyasu Okamura, Takaaki Ito, Yoshiyasu Kato, Mihoko Yamada, Katsuhiko Uesaka
BACKGROUND: There are a few reports that compare the rate of postoperative complications between subtotal stomach-preserving pancreatoduodenectomy (SSPPD) and antrectomy-combined pancreatoduodenectomy (ACPD), especially with respect to delayed gastric emptying (DGE) after pancreatoduodenectomy (PD). METHODS: From 2002 to 2013, 628 patients who underwent SSPPD (n = 78) or ACPD (n = 550) were enrolled in this study. The rate of DGE and the nutritional status were compared between patients receiving ACPD and SSPPD...
May 4, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28441659/perioperative-serum-carcinoembryonic-antigen-levels-predict-recurrence-and-survival-of-patients-with-pathological-t2-4-gastric-cancer-treated-with-curative-gastrectomy
#8
Hiroaki Uda, Mitsuro Kanda, Chie Tanaka, Daisuke Kobayashi, Kenichi Inaoka, Yuri Tanaka, Masamichi Hayashi, Naoki Iwata, Suguru Yamada, Tsutomu Fujii, Hiroyuki Sugimoto, Kenta Murotani, Michitaka Fujiwara, Yasuhiro Kodera
BACKGROUND/AIMS: Do serum carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 levels serve as prognostic indicators in patients with gastric cancer (GC)? This is a question that has long been disputed. The aim of this study was to evaluate the significance of perioperative serum levels of CEA and CA19-9 for predicting the recurrence and long-term survival after patients with pT2-4 GC undergo curative gastrectomy. METHODS: This study included 251 patients with radically resected pT2-4 GC without preoperative treatment...
April 26, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28441658/risk-factors-for-anastomotic-leakage-of-esophagojejunostomy-after-laparoscopy-assisted-total-gastrectomy-for-gastric-cancer
#9
Masanori Oshi, Chikara Kunisaki, Hiroshi Miyamoto, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo
BACKGROUND/AIMS: The study aimed to clarify the risk factors for anastomotic leakage after laparoscopy-assisted total gastrectomy (LATG) for gastric cancer. METHODS: In this study, we enrolled 131 patients with preoperatively diagnosed early gastric cancer who underwent LATG by a single surgeon between June 2006 and February 2014 at the Department of Surgery, Gastroenterological Center, Yokohama City University. Risk factors for anastomotic leakage (esophagojejunostomy) after LATG were retrospectively evaluated by univariate and multivariate analyses...
April 26, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28384642/incidence-of-and-risk-factors-and-reinterventions-for-post-pancreatoduodenectomy-hemorrhage-retrospective-analysis
#10
Wei-Guo Wang, Lan Fu, Shah Ram Babu, Li Wang, Cui-Ping Liang, Bo-Le Tian
AIMS: To analyze the incidence of and risk factors for post-pancreatoduodenectomy (PD) hemorrhage (PPH) and to evaluate the outcomes of reinterventions for PPH. METHODS: All PDs between January 2009 and December 2014 were retrospectively evaluated. PPH was evaluated according to the criteria of the International Study Group of Pancreatic Surgery. Both univariate and multivariate analyses of risk factors for PPH and mortality were performed. Reinterventions were also evaluated...
April 7, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28380478/anal-function-after-surgery-for-low-lying-rectal-cancer-comparison-of-mechanical-and-hand-sewn-coloanal-anastomosis
#11
Rie Matsunaga, Yuji Nishizawa, Norio Saito, Mitsuru Yokota, Ryuichi Hayashi, Masaaki Ito
BACKGROUND/AIMS: Mechanical coloanal anastomosis (MCAA) or hand-sewn coloanal anastomosis (HCAA) are used in anus-preserving surgery for low-lying rectal cancer. Either method can be used if the lower edge of the tumor is 4-6 cm from the anal verge. The goal of this study was to evaluate differences in the anal function after MCAA or HCAA. METHODS: The subjects were 305 consecutive patients with primary rectal cancer tumors situated 4-6 cm from the anal verge who underwent curative anus-preserving surgery between 2004 and 2013...
April 6, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28376488/laparoscopic-versus-hybrid-approach-for-treatment-of-incisional-ventral-hernia
#12
Mirella Ahonen-Siirtola, Tero Rautio, Fausto Biancari, Pasi Ohtonen, Jyrki Mäkelä
BACKGROUND: The aim of this study was to compare the efficacy of a hybrid approach (HA) versus laparoscopy in reducing the risk of complications related to complex adhesiolysis in incisional ventral hernia repair (IVHR). METHODS: This study included 269 adult patients who underwent laparoscopic IVHR at the Oulu University Hospital, Finland during 2006-2012. Baseline, operative and postoperative data was collected and compared between the treatment groups; that is, a comparison was made between the laparoscopic approach (LA, 38 patients) and the hybrid approach (HA, 24 patients)...
April 5, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28343221/abandoning-prophylactic-abdominal-drainage-after-hepatic-surgery-10-years-of-no-drain-policy-in-an-enhanced-recovery-after-surgery-environment
#13
Edgar M Wong-Lun-Hing, Victor van Woerden, Toine M Lodewick, Marc H A Bemelmans, Steven W M Olde Damink, Cornelis H C Dejong, Ronald M van Dam
BACKGROUND: Routine prophylactic abdominal drainage after hepatic surgery is still being debated, as it may be unnecessary, possibly harmful, and uncomfortable for patients. This study evaluated the safety of a no-drain policy after liver resection within an Enhanced Recovery after Surgery (ERAS) programme. METHODS: All hepatectomies performed without prophylactic drainage during 2005-2014 were included. Primary end points were resection-surface-related (RSR) morbidity, defined as the presence of postoperative biloma, hemorrhage or abscess, and reinterventions...
March 25, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28319941/short-term-outcomes-after-simultaneous-colorectal-and-major-hepatic-resection-for-synchronous-colorectal-liver-metastases
#14
Yoshihiro Ono, Akio Saiura, Junichi Arita, Yu Takahashi, Michiro Takahashi, Yosuke Inoue
BACKGROUND/AIMS: Resection of the liver is the standard therapeutic approach for patients with hepatic metastasis and is the only therapy with curative potential. The optimal timing of surgical resection for synchronous metastases has remained controversial. METHODS: From January 1993 to December 2008, our strategy has been to use simultaneous resection for resectable synchronous colorectal and liver metastases. During this period, 115 patients underwent simultaneous colorectal and hepatic resection...
March 21, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28315875/systematic-review-of-exocrine-pancreatic-insufficiency-after-gastrectomy-for-cancer
#15
Jennifer Straatman, Jim Wiegel, Nicole van der Wielen, E P Jansma, Miguel A Cuesta, Donald L van der Peet
BACKGROUND: Survival rates after a total gastrectomy with adequate lymphadenectomy are improving, leading to a shift in outcomes of interest from survival to postoperative outcomes and symptoms. In this systematic review, we investigate gastrointestinal symptoms that occur after a gastrectomy in relation to exocrine pancreatic insufficiency and the effect of pancreatic exocrine enzyme supplementation on these symptoms. METHODS: Online databases PubMed, Embase, and Cochrane Library were systematically searched in accordance with the PRISMA guidelines...
March 18, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28301853/chronic-mesenteric-ischemia-patient-outcomes-using-open-surgical-revascularization
#16
Markus U Wagenhäuser, Yvonne K Meyer-Janiszewski, Philip Dueppers, Joshua M Spin, Nikolaos Floros, Hubert Schelzig, Mansur Duran
BACKGROUND: Chronic mesenteric ischemia (CMI) is a rare disease. Open treatment (OT) remains a valuable treatment option. We analyzed patient outcomes after OT and investigated health-related quality of life (HRQoL). METHODS: Data were analyzed retrospectively. The investigation period was from January 1, 2001, to December 31, 2014. We investigated mortality and patency rates using Kaplan-Meier analysis. HRQoL was measured using a 36-item health survey. Various statistical methods were employed...
March 17, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28288461/clinical-pattern-of-recurrent-disease-during-the-follow-up-of-rectal-carcinoma
#17
Thijs Wieldraaijer, Pascal Bruin, Laura A M Duineveld, Pieter J Tanis, Anke B Smits, Henk C P M van Weert, Jan Wind
BACKGROUND/AIMS: Several initiatives have started to transfer colorectal cancer follow-up (FU) from secondary to primary care. For this purpose, it is important to assess when and how recurrences of rectal carcinoma are detected after treatment with curative intent. METHODS: Retrospective multicentre cohort study. Patients participating in an FU programme after curative intended treatment for rectal cancer stages I-III between 2007 and 2014. RESULTS: Of the 378 patients, 64 (17%) developed recurrent disease (RD)...
March 14, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28278493/management-and-outcomes-of-pancreatic-resections-performed-in-high-volume-referral-and-low-volume-community-hospitals-lead-by-surgeons-who-shared-the-same-mentor-the-importance-of-training
#18
Giovanni Capretti, Gianpaolo Balzano, Luca Gianotti, Marco Stella, Giovanni Ferrari, Paolo Baccari, Walter Zuliani, Marco Braga, Alessandro Zerbi
BACKGROUND: High hospital volume improves outcomes after pancreatic resection. The aim of this study was to assess if practice and outcomes differed between high- and low-volume centers across which chief surgeons shared a similar training and mentoring. METHODS: Data on patients undergoing standard pancreatic resections (2010-2013) at 7 Italian hospitals were collected. Chiefs of pancreatic surgery at each hospital had received the same training, with the same mentor...
March 10, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28226330/nutritional-recovery-after-open-and-laparoscopic-distal-gastrectomy-for-early-gastric-cancer-a-prospective-multicenter-comparative-trial-ccog1204
#19
Hidenobu Matsushita, Chie Tanaka, Kenta Murotani, Kazunari Misawa, Seiji Ito, Yuichi Ito, Mitsuro Kanda, Yoshinari Mochizuki, Kiyoshi Ishigure, Toyohisa Yaguchi, Jin Teramoto, Hiroshi Nakayama, Yoshihisa Kawase, Michitaka Fujiwara, Yasuhiro Kodera
BACKGROUND: Little information from prospective clinical trials is available on the influences of surgical approaches on postoperative body compositions and nutritional status. We designed a prospective non-randomized trial to compare postoperative chronological changes in body composition and nutritional status between laparoscopic and open distal gastrectomy for stage I gastric cancer (GC). METHODS: Body compositions and nutritional indicators in blood tests were measured at the baseline and at the 1st, 3rd, 6th, and 12th postoperative months (POM)...
February 23, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28219066/intraoperative-identification-of-colonic-tumor-sites-using-a-near-infrared-fluorescence-endoscopic-imaging-system-and-indocyanine-green
#20
Makoto Watanabe, Masahiko Murakami, Yoshiaki Ozawa, Sota Yoshizawa, Nobuaki Matsui, Takeshi Aoki
BACKGROUND: This study aimed to investigate the feasibility of the PINPOINT® Endoscopic Fluorescence Imaging System (PINPOINT) for intraoperative identification of colonic tumor sites during laparoscopic colorectal surgery. METHODS: Eighty consecutive patients with colorectal cancer were prospectively enrolled. Preoperatively, 0.5 mL of indocyanine green (ICG; 2.5 mg/mL) was injected into the submucosal space only at the distal side of the tumor under colonoscopy...
February 21, 2017: Digestive Surgery
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