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Diabetic Medicine: a Journal of the British Diabetic Association

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https://www.readbyqxmd.com/read/28929513/association-between-hba1c-and-peripheral-neuropathy-in-a-10-year-follow-up-study-of-people-with-normal-glucose-tolerance-impaired-glucose-tolerance-and-type-2-diabetes
#1
M Peterson, R Pingel, N Lagali, L B Dahlin, O Rolandsson
AIMS: To explore the association between HbA1c and sural nerve function in a group of people with normal glucose tolerance, impaired glucose tolerance or Type 2 diabetes. METHODS: We conducted a 10-year follow-up study in 87 out of an original 119 participants. At study commencement (2004), 64 men and 55 women (mean age 61.1 years) with normal glucose tolerance (n=39), impaired glucose tolerance (n=29), or Type 2 diabetes (n=51) were enrolled. At the 2014 follow-up (men, n=46, women, n=41; mean age 71...
September 20, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28921676/perioperative-passport-empowering-people-with-diabetes-along-their-surgical-journey
#2
E Page, F Akiboye, S Jackson, C Kerry, R Round, G Rayman
AIM: To determine whether a handheld 'perioperative passport' could improve the experience of perioperative care for people with diabetes and overcome some of the communication issues commonly identified in inpatient extracts. METHODS: Individuals with diabetes undergoing elective surgery requiring at least an overnight stay were identified via a customized information technology system. Those allocated to the passport group were given the perioperative passport before their hospital admission...
September 18, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28905434/decline-of-insulin-therapy-and-delays-in-insulin-initiation-in-people-with-uncontrolled-diabetes-mellitus
#3
N Hosomura, S Malmasi, D Timerman, V J Lei, H Zhang, L Chang, A Turchin
AIMS: To design and validate a natural language processing algorithm to identify insulin therapy decline from the text of physician notes, and to determine the prevalence of insulin therapy decline and its impact on insulin initiation. METHODS: We designed the algorithm using the publicly available natural language processing platform Canary. We evaluated the accuracy of the algorithm on 1501 randomly selected primary care physicians' notes from the electronic medical record system of a large academic medical centre...
September 14, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28905421/exercise-to-preserve-%C3%AE-cell-function-in-recent-onset-type-1-diabetes-mellitus-extod-a-randomized-controlled-pilot-trial
#4
P Narendran, N Jackson, A Daley, D Thompson, K Stokes, S Greenfield, M Charlton, M Curran, T P J Solomon, A Nouwen, S I Lee, A R Cooper, M Mostazir, R S Taylor, A Kennedy, R C Andrews
AIM: Residual β-cell function is present at the time of diagnosis with Type 1 diabetes. Preserving this β-cell function reduces complications. We hypothesized that exercise preserves β-cell function in Type 1 diabetes and undertook a pilot trial to address the key uncertainties in designing a definitive trial to test this hypothesis. METHODS: A randomized controlled pilot trial in adults aged 16-60 years diagnosed with Type 1 diabetes within the previous 3 months was undertaken...
September 14, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28898445/characterizing-adults-with-type-2-diabetes-mellitus-and-intellectual-disability-outcomes-of-a-case-finding-study
#5
L D Bryant, A M Russell, R E A Walwyn, A J Farrin, A Wright-Hughes, E H Graham, D Nagi, A Stansfield, J Birtwistle, S Meer, R A Ajjan, A O House
AIMS: To report the results of a case-finding study conducted during a feasibility trial of a supported self-management intervention for adults with mild to moderate intellectual disability and Type 2 diabetes mellitus, and to characterize the study sample in terms of diabetes control, health, and access to diabetes management services and support. METHODS: We conducted a cross-sectional case-finding study in the UK (March 2013 to June 2015), which recruited participants mainly through primary care settings...
September 12, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28891210/measuring-type-1-diabetes-stigma-development-and-validation-of-the-type-1-diabetes-stigma-assessment-scale-dsas-1
#6
J L Browne, A D Ventura, K Mosely, J Speight
AIMS: To develop and validate a self-report measure designed to assess perceived and experienced stigma for adults with Type 1 diabetes: the Type 1 Diabetes Stigma Assessment Scale. METHODS: A large item-pool (64 items) was drafted based on qualitative data from interviews with 27 adults with Type 1 diabetes. Eleven adults with Type 1 diabetes completed the draft questionnaire (responding to items using a five-point Likert scale), and participated in cognitive debriefing interviews...
September 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28887847/fournier-s-gangrene-in-a-man-on-empagliflozin-for-treatment-of-type-2-diabetes
#7
S Kumar, A J Costello, P G Colman
Use of sodium glucose co-transporter 2 (SLGT2) inhibitors has been associated with an increased risk of genital infections secondary to increased glycosuria [1]. Our report highlights a case of Fournier's gangrene, the most severe and potentially fatal type of genital infection, which was preceded by multiple episodes of thrush in a man treated with empagliflozin for Type 2 diabetes. This article is protected by copyright. All rights reserved.
September 8, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28887815/systematic-review-and-meta-analysis-of-the-efficacy-of-interventions-for-people-with-type-1-diabetes-mellitus-and-disordered-eating
#8
P Clery, D Stahl, K Ismail, J Treasure, C Kan
AIM: To examine the types of interventions currently available for people with Type 1 diabetes mellitus and their effectiveness. BACKGROUND: The prevalence of disordered eating in people with Type 1 diabetes mellitus is twice that in their counterparts without diabetes, and is associated with worse biomedical outcomes and greater mortality. METHODS: Medline, Embase, PsycINFO, the Cochrane Library, PubMed and OpenGrey databases were searched up to August 2016 to identify studies on interventions in people with Type 1 diabetes-associated disordered eating...
September 8, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28856721/focus-group-study-to-identify-the-central-facets-of-fear-of-hypoglycaemia-in-people-with-type-2-diabetes-mellitus
#9
J Grammes, W Stock, C G Mann, E M Flynn, T Kubiak
AIMS: To determine key worries about hypoglycaemia among insulin-using adults with Type 2 diabetes using a focus group approach. METHODS: Thirteen focus groups were conducted in three diabetes outpatient care units and one peer support group was set up, in Germany. A total of 64 insulin-dependent adults with Type 2 diabetes (36.5% women, mean age 65.2 ± 11.0 years) discussed their worries about hypoglycaemia. The qualitative results were assigned into thematic categories using a bottom-up coding procedure...
August 30, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28833535/hba1c-variability-is-associated-with-increased-mortality-and-earlier-hospital-admission-in-people-with-type-1-diabetes
#10
G S Walker, S G Cunningham, C A R Sainsbury, G C Jones
AIM: Despite evidence of morbidity, no evidence exists on the relationship between HbA1c variability and mortality in Type 1 diabetes. We performed an observational study to investigate whether the association between HbA1c variability and mortality exists in a population of people with Type 1 diabetes. As a secondary outcome, we compared onset of first hospital admission between groups. METHODS: People with Type 1 diabetes were identified for inclusion from the Scottish Care Information - Diabetes data set...
August 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28833481/exploring-residual-risk-for-diabetes-and-microvascular-disease-in-the-diabetes-prevention-program-outcomes-study-dppos
#11
L Perreault, Q Pan, V R Aroda, E Barrett-Connor, D Dabelea, S Dagogo-Jack, R F Hamman, S E Kahn, K J Mather, W C Knowler, The Diabetes Prevention Program Research Group
AIM: Approximately half of the participants in the Diabetes Prevention Outcomes Study (DPPOS) had diabetes after 15 years of follow-up, whereas nearly all the others remained with pre-diabetes. We examined whether formerly unexplored factors in the DPPOS coexisted with known risk factors that posed additional risk for, or protection from, diabetes as well as microvascular disease. METHODS: Cox proportional hazard models were used to examine predictors of diabetes...
August 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28799294/the-prevalence-of-diabetes-specific-emotional-distress-in-people-with-type-2-diabetes-a-systematic-review-and-meta-analysis
#12
N E Perrin, M J Davies, N Robertson, F J Snoek, K Khunti
AIMS: Psychological comorbidity, such as depression and/or diabetes-specific emotional distress (diabetes distress), is widespread in people with Type 2 diabetes and is associated with poorer treatment outcomes. Although extensive research into the prevalence of depression has been conducted, the same attention has not been given to diabetes distress. The aim of this systematic review was to determine the overall prevalence of diabetes distress in people with Type 2 diabetes. METHODS: Seven databases were searched to identify potentially relevant studies; eligible studies (adult population aged > 18 years with Type 2 diabetes and an outcome measure of diabetes distress) were selected and appraised independently by two reviewers...
August 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28799282/self-compassion-is-associated-with-optimum-self-care-behaviour-medical-outcomes-and-psychological-well-being-in-a-cross-sectional-sample-of-adults-with-diabetes
#13
M Ferrari, M Dal Cin, M Steele
AIM: To investigate the role of self-compassion in diabetes outcomes, a construct which may be relevant to chronic conditions, given its focus on compassion toward oneself, especially in times of difficulty. METHODS: In this cross-sectional study we collected data online from 310 adults diagnosed with diabetes. The questionnaire measured three primary outcomes: self-management behaviours; HbA1c levels and psychological well-being. Potential predictors were also assessed, including self-compassion, locus of control, social support and demographics...
August 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28799221/repose-repositioning-insulin-pump-therapy-in-type-1-diabetes
#14
N S Oliver
In 2008, the National Institute for Health and Care Excellence (NICE) technology appraisal of continuous subcutaneous insulin infusion (CSII, insulin pump therapy) for people with Type 1 diabetes was published [1]. Implementation of this enables children under the age of 12 years to access CSII, and consideration of CSII for adults and children over 12 years with challenging hypo- or hyperglycaemia. In Scotland, the Scottish Intercollegiate Guidelines Network (SIGN) guidance for management of diabetes states that CSII therapy should be considered for people unable to achieve their glycaemic targets, for those who experience recurring episodes of severe hypoglycaemia, and in infants and very young children with very low basal insulin requirements, for whom even small doses of basal insulin analogue may result in hypoglycaemia [2]...
August 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28799212/excess-psychosocial-burden-in-women-with-diabetes-and-premature-acute-coronary-syndrome
#15
T M Peters, R Pelletier, H Behlouli, A M Rossi, L Pilote
AIM: Diabetes is a stronger risk factor for acute coronary syndrome for women than men. We investigate whether behavioural and psychosocial factors contribute to the disparity in acute coronary syndrome risk and outcomes among women with diabetes relative to women without diabetes and men. METHODS: Among 939 participants in the GENESIS-PRAXY cohort study of premature acute coronary syndrome (age ≤ 55 years), we compared the prevalence of traditional and non-traditional factors by sex and Type 2 diabetes status...
August 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28799203/efficacy-and-safety-of-alirocumab-in-people-with-prediabetes-vs-those-with-normoglycaemia-at-baseline-a-pooled-analysis-of-10-phase-iii-odyssey-clinical-trials
#16
L A Leiter, D Müller-Wieland, M T Baccara-Dinet, A Letierce, R Samuel, B Cariou
AIM: To assess the lipid-lowering efficacy and safety of alirocumab, a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, in people with hypercholesterolaemia and prediabetes at baseline vs people with normoglycaemia at baseline in a pooled analysis of 10 ODYSSEY phase III trials. METHODS: People classified as having prediabetes had baseline HbA1c ≥39 mmol/mol (5.7%) and <48 mmol/mol (6.5%), or two baseline fasting plasma glucose values ≥5.6 mmol/l (100 mg/dl) but no more than one fasting plasma glucose value ≥7...
August 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28792638/transmission-of-type-2-diabetes-to-sons-and-daughters-the-d-e-s-i-r-cohort
#17
B Balkau, R Roussel, S Wagner, J Tichet, P Froguel, G Fagherazzi, F Bonnet
AIMS: To document the family transmission of Type 2 diabetes to men and women. METHOD: The French D.E.S.I.R. cohort followed men and women over 9 years, with 3-yearly testing for incident Type 2 diabetes. First- and/or second-degree family histories of diabetes were available for 2187 men and 2282 women. Age-adjusted hazard ratios were estimated for various family members and groupings of family members, as well as for a genetic diabetes risk score, based on 65 diabetes-associated loci...
August 9, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28792634/meeting-american-diabetes-association-diabetes-management-targets-trends-in-mauritius
#18
M Tabesh, J E Shaw, P Z Zimmet, S Soderberg, S Kowlessur, M Timol, N Joonas, G M M Alberti, J Tuomilehto, B J Shaw, D J Magliano
AIMS: To examine the proportion of people with diabetes in the multi-ethnic country of Mauritius meeting American Diabetes Association targets in 2009 and 2015. METHODS: Data from independent population-based samples of 858 and 656 adults with diagnosed diabetes in 2009 and 2015, respectively, were analysed with regard to recommended American Diabetes Association targets for HbA1c , blood pressure and LDL cholesterol. RESULTS: In 2015 compared with 2009, the proportion of people achieving American Diabetes Association targets for glycaemic control in Mauritius was higher in women (P≤0...
August 9, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28792627/physical-activity-and-type-1-diabetes-an-underused-therapy
#19
T Yates, M J Davies
Aerobic exercise training has consistently been shown to be an effective therapy in the management of Type 2 diabetes, resulting in reductions in HbA1c of ~8 mmol/mol (0.7%) [1]. Moreover, physical activity and cardiorespiratory fitness have been strongly associated with a decreased risk of morbidity and mortality in those with Type 2 diabetes. Despite a wealth of evidence for Type 2 diabetes, less is understood about the therapeutic potential of physical activity in Type 1 diabetes. This article is protected by copyright...
August 9, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28782842/diabetes-risk-in-women-with-gestational-diabetes-mellitus-and-a-history-of-polycystic-ovary-syndrome-a-retrospective-cohort-study
#20
R Bond, R Pace, E Rahme, K Dasgupta
AIMS: To investigate whether polycystic ovary syndrome further increases postpartum diabetes risk in women with gestational diabetes mellitus and to explore relationships between polycystic ovary syndrome and incident diabetes in women who do not develop gestational diabetes. METHODS: This retrospective cohort study (Quebec Physician Services Claims; Hospitalization Discharge Databases; Birth and Death registries) included 34 686 women with gestational diabetes during pregnancy (live birth), matched 1:1 to women without gestational diabetes by age group, year of delivery and health region...
August 7, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
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