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Diabetic Medicine: a Journal of the British Diabetic Association

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https://www.readbyqxmd.com/read/28326628/incidence-recurrence-and-cost-of-hyperglycaemic-crises-requiring-emergency-treatment-in-andalusia-spain
#1
R J Barranco, F Gomez-Peralta, C Abreu, M Delgado-Rodriguez, A Moreno-Carazo, F Romero, M A de la Cal, J M Barranco, F J Pasquel, G E Umpierrez
AIMS: Hyperglycaemic crises (diabetic ketoacidosis and hyperosmolar hyperglycaemic state) are medical emergencies in people with diabetes. We aimed to determine their incidence, recurrence and economic impact. METHODS: An observational study of hyperglycaemic crises cases using the database maintained by the out-of-hospital emergency service, the Healthcare Emergency Public Service (EPES) during 2012. The EPES provides emergency medical services to the total population of Andalusia, Spain (8...
March 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28326618/comparative-study-of-hba1c-and-fasting-plasma-glucose-vs-the-oral-glucose-tolerance-test-for-diagnosis-of-diabetes-in-people-with-tuberculosis
#2
H Aftab, A Ambreen, M Jamil, P Garred, J H Petersen, S D Nielsen, I C Bygbjerg, D L Christensen
AIM: To compare HbA1c and fasting plasma glucose assessment, with the 2-h oral glucose tolerance test as reference, in screening for diabetes in people with turberculosis. METHODS: Individuals (N=268) with newly diagnosed smear-positive tuberculosis were screened for diabetes at a tertiary hospital in Lahore, Pakistan. Diabetes diagnosis was based on WHO criteria: thresholds were ≥ 48 mmol/mol (≥6.5%) for HbA1c and ≥7.0mmol/l for fasting plasma glucose. RESULTS: The proportion of participants diagnosed with diabetes was 4...
March 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28326603/response-to-early-view-an-opportunity-for-enhanced-peer-review
#3
Tonja Nansel, Aiyi Liu, Benjamin Gee
We welcome the anonymous readers' interest in our advance-access manuscript, and appreciate the opportunity to respond to the Editor's comments on our article as it reaches the Journal's pages in print. First, the Editor suggests 'it may be incorrect to state that the intervention led to a reduction in hypoglycaemia rates' because the study did not report the change in hypoglycaemia rates from baseline. The aim of our study was to compare rates of adverse events between intervention and control groups during the course of the trial...
March 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28321905/differential-increments-of-basal-glucagon-like-1-peptide-concentration-among-slc47a1-rs2289669-genotypes-were-associated-with-inter-individual%C3%A2-variability-in%C3%A2-glycaemic-response-to-metformin-in-chinese-people-with-newly-diagnosed-type-2-diabetes
#4
H Liang, W Xu, L Zhou, W Yang, J Weng
AIM: To elucidate the effects of rs2289669, an intron variant of the SLC47A1 gene, on metformin responses in Chinese people with newly diagnosed Type 2 diabetes. METHODS: We conducted a nationwide, multicentre, prospective clinical trial, in which rs2289669 was genotyped, using Sequenom, in 291 participants. The changes in HbA1c were compared among rs2289669 genotypes, and associations with rs2289669 were evaluated using linear regression analysis. RESULTS: We found that, compared with participants with a homozygous G allele, those carrying the minor A allele had significantly greater HbA1c reduction and increases in basal glucagon-like peptide-1 concentration...
March 21, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28295529/factors-determining-uptake-of-diabetic-retinopathy-screening-in-oxfordshire
#5
R B R Moreton, I M Stratton, S J Chave, H Lipinski, P H Scanlon
AIMS: To investigate variables at the demographic and primary care practice levels that influence the uptake of diabetic retinopathy screening. METHODS: Data were extracted from the management software of one screening programme for 21 797 people registered with 79 general practices. Uptake was examined by gender, age group, modality of screening (mobile unit at general practice versus high-street optometrist), and by general practice. A telephone survey of high-street optometrists provided information on the availability of screening appointments...
March 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28294392/cost-effectiveness-of-population-based-community-workplace-and-individual-policies-for-diabetes-prevention-in-the-uk
#6
P R Breeze, C Thomas, H Squires, A Brennan, C Greaves, P Diggle, E Brunner, A Tabak, L Preston, J Chilcott
AIM: To analyse the cost-effectiveness of different interventions for Type 2 diabetes prevention. within a common framework METHODS: A micro-simulation model was developed to evaluate the cost-effectiveness of a range of diabetes prevention interventions including: (1) soft drinks taxation; (2) retail policy in socially deprived areas; (3) workplace intervention; (4) community-based intervention; and (5) screening and intensive lifestyle intervention in individuals with high diabetes risk...
March 10, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28294386/integrated-primary-care-is-this-the-solution-to-the-diabetes-epidemic
#7
S Seidu, M J Davies, A Farooqi, K Khunti
The prevalence of Type 2 diabetes mellitus is rising exponentially across the globe [1], mainly as a result of changes in lifestyle [2]. Other factors accounting for this rise include proactive screening, people with diabetes living longer and an ageing general population [3]. With the increasing age comes an increase in the prevalence of chronic diseases and multimorbidity [4]. People with diabetes not only develop complications directly related to the condition, but also often have multimorbidities in addition to their diabetes [4]...
March 10, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28257160/increasing-the-protein-quantity-in-a-meal-results-in-dose-dependent-effects-on-postprandial-glucose-levels-in-individuals-with-type-1-diabetes-mellitus
#8
M A Paterson, C E M Smart, P E Lopez, P Howley, P McElduff, J Attia, C Morbey, B R King
AIM: To determine the glycaemic impact of increasing protein quantities when consumed with consistent amounts of carbohydrate in individuals with Type 1 diabetes on intensive insulin therapy. METHODS: Participants with Type 1 diabetes [aged 10-40 years, HbA1c ≤ 64 mmol/mol (8%), BMI ≤ 91(st) percentile] received a 30-g carbohydrate (negligible fat) test drink daily over 5 days in randomized order. Protein (whey isolate 0 g/kg carbohydrate, 0 g/kg lipid) was added in amounts of 0 (control), 12...
March 3, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28257159/the-effect-of-an-education-programme-medias-2-bsc-of-non-intensive-insulin-treatment-regimens-for-people-with-type%C3%A2-2-diabetes-a-randomized-multi-centre-trial
#9
N Hermanns, D Ehrmann, S Schall, B Maier, T Haak, B Kulzer
AIMS: A self-management oriented education programme (MEDIAS 2 BSC) for people with Type 2 diabetes who are on a non-intensive insulin treatment regimen was developed. In a randomized, multi-centre trial, the effect of MEDIAS 2 BSC was compared with an established education programme that acted as a control group. METHODS: The primary outcome was the impact of MEDIAS 2 BSC on glycaemic control. Secondary outcomes included the incidence of severe hypoglycaemia, hypoglycaemia unawareness, diabetes-related distress, diabetes knowledge, quality of life and self-care behaviour...
March 3, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28257151/updated-24-year-trend-of-type%C3%A2-1-diabetes-incidence-in-children-in-poland-reveals-a-sinusoidal-pattern-and-sustained-increase
#10
A Chobot, J Polanska, A Brandt, G Deja, B Glowinska-Olszewska, O Pilecki, A Szadkowska, M Mysliwiec, P Jarosz-Chobot
AIMS: To present the incidence trend for Type 1 diabetes in Polish children aged 0-14 years, updated using data collected during 2005-2012, and assess the reliability of the predictive model constructed previously using the 1989-2004 database. METHODS: Children aged < 15 years with newly diagnosed Type 1 diabetes are recorded prospectively (EURODIAB criteria) in several regional registers in Poland. Age- and gender-standardized incidence rates for Type 1 diabetes were calculated per 100 000 persons/year...
March 3, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28226200/effectiveness-of-group-based-self-management-education-for-individuals-with-type%C3%A2-2-diabetes-a-systematic-review-with-meta-analyses-and-meta-regression
#11
K Odgers-Jewell, L E Ball, J T Kelly, E A Isenring, D P Reidlinger, R Thomas
AIMS: Patient education for the management of Type 2 diabetes can be delivered in various forms, with the goal of promoting and supporting positive self-management behaviours. This systematic review aimed to determine the effectiveness of group-based interventions compared with individual interventions or usual care for improving clinical, lifestyle and psychosocial outcomes in people with Type 2 diabetes. METHODS: Six electronic databases were searched. Group-based education programmes for adults with Type 2 diabetes that measured HbA1c and followed participants for ≥ 6 months were included...
February 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28226193/care-of-women-with-diabetes-before-during-and-after-pregnancy-time-for-a-new-approach
#12
A M Egan, L Carmody, B Kirwan, F P Dunne
AIMS: This study assesses the impact of pregnancy and pre-pregnancy care on longer-term treatment goals in women with diabetes. METHODS: This retrospective study included women with Type 1 (n = 247) and Type 2 diabetes (n = 137) who were evaluated before, during and after pregnancy. RESULTS: Among women with Type 1 diabetes, average HbA1c at 12 months post-partum was similar to the preconception level [63 vs. 64 mmol/mol (7.9% vs...
February 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28226187/systematic-review-of-treatments-for-diabetic-peripheral-neuropathy-lost-in-translation
#13
I A Volchegorskii
We read with great interest the systematic review by Çakici et al. [1] on treatments for diabetic peripheral neuropathy. Unfortunately, on careful reading, we found a number of inaccuracies and factual errors. First, we were rather surprised that there was almost no mention of mexidol, although a conclusion about its effectiveness in treating diabetic peripheral neuropathy is in the 'What's new?' section, as well as in the final sentence of the main text under the 'Strengths and limitations' section and in the abstract...
February 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28226183/development-of-an-acceptable-and-feasible-self-management-group-for-children-young-people-and-families-living-with-type-1-diabetes
#14
R A Cai, R I G Holt, L Casdagli, R M Viner, R Thompson, K Barnard, D Christie
AIMS: This study developed an acceptable and feasible self-management intervention that addresses the self-identified needs of children and young people with Type 1 diabetes and their parents. METHODS: Phase 1 reviewed previous interventions and interviewed the clinical team, young people and families. Phase 2 ran three age-matched focus groups with 11 families of children aged 8-16 years. Feedback was used to modify the workshop. Phase 3 evaluated feasibility of delivery, as well as the effects on metabolic control, quality of life and fear of hypoglycaemia, measured at baseline and 1-3 months post intervention...
February 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28226181/use-of-self-collected-capillary-blood-samples-for-islet-autoantibody-screening-in-relatives-a-feasibility-and-acceptability-study
#15
Y Liu, L E Rafkin, D Matheson, C Henderson, D Boulware, R E J Besser, C Ferrara, L Yu, A K Steck, P J Bingley
AIMS: To evaluate the feasibility of using self-collected capillary blood samples for islet autoantibody testing to identify risk in relatives of people with Type 1 diabetes. METHODS: Participants were recruited via the observational TrialNet Pathway to Prevention study, which screens and monitors relatives of people with Type 1 diabetes for islet autoantibodies. Relatives were sent kits for capillary blood collection, with written instructions, an online instructional video link and a questionnaire...
February 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28199038/the-duration-of-intrapartum-maternal-hyperglycaemia-predicts-neonatal-hypoglycaemia-in-women-with-pre-existing-diabetes
#16
T Joshi, C Oldmeadow, J Attia, K Wynne
AIM: There is a high incidence of neonatal hypoglycaemia in neonates born to mothers with pre-existing diabetes. This often necessitates admission to the neonatal intensive care. Guidelines suggest maintaining intrapartum blood glucose levels (BGLs) of 4-7 mmol/l in women with diabetes to reduce the risk of neonatal hypoglycaemia. This study assessed whether intrapartum BGLs in women with pre-gestational Type 1 and 2 diabetes were predictive of neonatal hypoglycaemia. METHODS: A retrospective analysis of 261 births delivered at a tertiary hospital in Australia from 2009 to 2014...
February 15, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28199029/healthcare-costs-of-type-2-diabetes-in-germany
#17
E Jacobs, A Hoyer, R Brinks, A Icks, O Kuß, W Rathmann
AIM: To describe for the first time the direct costs of Type 2 diabetes treatment by analysing nationwide routine data from statutory health insurance in Germany. METHODS: This cost-of-illness-study was based on a 6.8% random sample of all German people with statutory health insurance (4.3 out of 70 million people). The healthcare expenses show direct per capita costs from the payer perspective. Healthcare expenses for physicians, dentists, pharmacies, hospitals, sick benefits and other healthcare costs were considered...
February 15, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28196291/factors-influencing-attendance-at-structured-education-for-type-1-diabetes-in-south-london
#18
S M Harris, P Shah, H Mulnier, A Healey, S M Thomas, S A Amiel, D Hopkins
AIM: To investigate the factors influencing uptake of structured education for people with Type 1 diabetes in our local population in order to understand why such uptake is low. METHODS: We conducted a cross-sectional database study of adults with Type 1 diabetes in two south London boroughs, analysed according to Dose Adjustment For Normal Eating (DAFNE) attendance or non-attendance. Demographics, glycaemic control and service use, with subset analysis by ethnicity, were compared using univariate analysis...
February 14, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28196274/glycated-haemoglobin-hba1c-and-fasting-plasma-glucose-relationships-in-sea-level-and-high-altitude-settings
#19
J C Bazo-Alvarez, R Quispe, T D Pillay, A Bernabé-Ortiz, L Smeeth, W Checkley, R H Gilman, G Málaga, J J Miranda
AIM: Higher haemoglobin levels and differences in glucose metabolism have been reported among high-altitude residents, which may influence the diagnostic performance of HbA1c . This study explores the relationship between HbA1c and fasting plasma glucose (FPG) in populations living at sea level and at an altitude of > 3000 m. METHODS: Data from 3613 Peruvian adults without a known diagnosis of diabetes from sea-level and high-altitude settings were evaluated...
February 14, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28195662/deficiencies-in-postgraduate-training-for-healthcare-professionals-who-provide-diabetes-education-and-support-results-from-the-diabetes-attitudes-wishes-and-needs-dawn2-study
#20
J L Byrne, M J Davies, I Willaing, R I G Holt, M E Carey, H Daly, S Skovlund, M Peyrot
AIMS: To consider the global provision of self-management diabetes education and training for healthcare professionals using data from the second Diabetes Attitudes, Wishes and Needs (DAWN2) study. METHODS: A total of 4785 healthcare professionals caring for people with diabetes were surveyed in 17 countries to assess diabetes healthcare provision, self-management support and training. RESULTS: Of the healthcare professionals surveyed, 33...
February 13, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
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