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Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine

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https://www.readbyqxmd.com/read/27909978/il-17a-produced-by-peritoneal-macrophages-promote-the-accumulation-and-function-of-granulocytic-myeloid-derived-suppressor-cells-in-the-development-of-colitis-associated-cancer
#1
Yue Zhang, Juan Wang, Wenxin Wang, Jie Tian, Kai Yin, Xinyi Tang, Jie Ma, Huaxi Xu, Shengjun Wang
It is widely acknowledged that a close relationship is between inflammation and colon cancer. Interleukin (IL)-17A and myeloid-derived suppressor cells (MDSCs) play an important role in the development of colitis-associated cancer (CAC). However, the precise changes of IL-17, MDSCs, and Th17 cells during the CAC progression have not been observed in the colorectal chronic inflammation-dependent tumor. In this study, we found the level of IL-17 was increased in pathogenic colon site during the early stage of CAC model...
December 1, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27900564/effects-of-rnai-mediated-tusc3-silencing-on-radiation-induced-autophagy-and-radiation-sensitivity-of-human-lung-adenocarcinoma-cell-line-a549-under-hypoxic-condition
#2
Ya-Guang Li, Nai-Xin Liang, Ying-Zhi Qin, Dong-Jie Ma, Chang-Jin Huang, Lei Liu, Shan-Qing Li
This study examined the effects of RNAi-mediated TUSC3 silencing on radiation-induced autophagy and radiation sensitivity of human lung adenocarcinoma cell line A549 under hypoxic condition. Different CoCl2 concentrations were used to treat A549 cells and establish a CoCl2-induced hypoxic model of A549 cells. MTT and clone formation assays were used to determine the effects of different concentrations of CoCl2 on the growth and proliferation of A549 cells treated by different doses of X-ray irradiation. The siRNA-expressing vector was transfected by liposomes and for silencing of TUSC3...
November 30, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27900563/lncrna-hotair-promotes-cisplatin-resistance-in-gastric-cancer-by-targeting-mir-126-to-activate-the-pi3k-akt-mrp1-genes
#3
Jin Yan, Yini Dang, Shiyu Liu, Yifeng Zhang, Guoxin Zhang
Altered expression of long noncoding RNAs (lncRNAs) has shown to associate with human cancer development and progression and drug resistance. LncRNA HOX antisense intergenic RNA (HOTAIR) regulates chromatin state and highly expressed in various human cancers. This study analyzed HOTAIR expression in gastric cancer cells and tissues and then assessed the effects of HOTAIR on modulation of gastric cancer cell sensitivity to cisplatin and the underlying molecular events. The data showed that HOTAIR was significantly upregulated in cisplatin-resistant gastric cancer cells and tissues compared with control cells and noncancerous gastric tissues...
November 30, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27896700/fat4-functions-as-a-tumor-suppressor-in-triple-negative-breast-cancer
#4
Lingmi Hou, Maoshan Chen, Xiaobo Zhao, Jingdong Li, Shishan Deng, Jiani Hu, Hongwei Yang, Jun Jiang
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is often associated with biologic behavior with frequent distant metastasis. FAT tumor suppressor homolog 4 (FAT4), a cadherin-related protein, is involved in a variety of biological processes as a tumor suppressor; however, the role of FAT4 in TNBC is still unclear. The aim of our study was to identify the role of FAT4 in TNBC and examine the underlying molecular mechanisms. The expression of FAT4 was evaluated by immunohistochemistry, western blotting, and qRT-PCR in a series of TNBC tissues...
November 28, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27864685/regulation-of-autophagy-by-ca-2
#5
REVIEW
Fang Sun, Xia Xu, Xiaohong Wang, Bei Zhang
Autophagy is an evolutionarily conserved lysosomal catabolic process used as an internal engine in response to nutrient starvation or metabolic stress. A number of protein complexes and an intricate network of stress signaling cascades impinge on the regulation of autophagy; the mammalian target of rapamycin serves as a canonical player. Ca(2+), as a major intracellular second messenger, regulates multiple physiological and pathological functions. Although significant information is already well-established about the role of Ca(2+) in apoptosis, its role in autophagy has been recently determined and is poorly understood...
November 18, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27858295/integrated-analysis-identified-an-intestinal-like-and-a-diffuse-like-gene-sets-that-predict-gastric-cancer-outcome
#6
Cheng Zhang, Li Min, Jiafei Liu, Wei Tian, Yong Han, Like Qu, Chengchao Shou
The two major histological types of gastric cancer, intestinal and diffuse subtypes, have distinct epidemiological and pathophysiological features and were also suggested to be of diverse clinical outcomes. Although the gene expression spectrum of gastric cancer subtypes has been reported by previous studies, its linkage with gastric cancer clinical features and outcomes remains elusive. We investigated large-sample online gastric cancer datasets for seeking genes correlated with the clinical diversities between gastric cancer intestinal and diffuse subtypes...
November 17, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27832471/expression-pattern-of-bccip-in-hepatocellular-carcinoma-is-correlated-with-poor-prognosis-and-enhanced-cell-proliferation
#7
Zhipeng Lin, Baoying Hu, Wenkai Ni, Xiaofei Mao, Huiling Zhou, Jiale Lv, Bihui Yin, Zhongyi Shen, Miaomiao Wu, Wensen Ding, Mingbing Xiao, Runzhou Ni
BCCIP was originally identified as a BRCA2- and CDKN1A- (Cip1/waf1/p21) interacting protein, also known as BCCIP. It has been reported to express in various types of cancers, including colorectal cancer (CRC), astrocytic brain tumors, and glioblastomas. However, the relationship between BCCIP expression and clinicopathological features of hepatocellular carcinoma (HCC) remains to be determined. Herein, we demonstrated that BCCIP was downregulated in clinical HCC tissues; its level was inversely correlated with multiple clinicopathological factors, such as tumor grade, tumor size, and Ki67 expression...
November 10, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27830468/a-novel-model-for-identification-of-prognostic-indicator-for-clinical-outcome-of-squamous-cell-lung-carcinoma
#8
Kai Duan, Li Li, Xiao-Dong Tan, Ping Yin
Squamous cell carcinoma of the lung (SCCL) is the most common and aggressive lung tumor with poor clinical outcome. Identification and development of potential genes in prognostic process could be beneficial for clinical management. Sequencing data of 300 SCCL samples at level 3 were downloaded from The Cancer Genome Atlas (TCGA) data portal. Single-factor survival analysis was performed by the Kaplan-Meier method. Functional annotation was conducted on the high-frequency genes filtered out by 1000 times of the least absolute shrinkage and selectionator operator regression analysis...
November 9, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27830467/microrna-92-promotes-invasion-and-chemoresistance-by-targeting-gsk3%C3%AE-and-activating-wnt-signaling-in-bladder-cancer-cells
#9
Haifeng Wang, Changxing Ke, Xingyong Ma, Qinghua Zhao, Mingying Yang, Wei Zhang, Jiansong Wang
miR-92 has been reported to be upregulated in several human cancers. Until now, its expression pattern and biological roles in human bladder cancer still remains unexplored. The present study aims to clarify its expression, function, and potential molecular mechanisms in bladder cancer. Using real-time PCR, we found that miR-92 was upregulated in bladder cancer tissues compared with normal bladder tissues. We transfected miR-92 mimic and inhibitor in T24 and 5637 bladder cancer cells separately. We found that miR-92 mimic promoted T24 proliferation and invasion, with increased expression of cyclin D1, c-myc, and MMP7 at both mRNA and protein levels...
November 9, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27826945/retraction-note-to-evaluation-of-gene-expression-level-of-cdc5l-and-macc1-in-poor-prognosis-and-progression-of-osteosarcoma
#10
Mohsen Mohammadi, Peyman Karimi Goudarzi, Omid Rahmani, Peyman Kaghazian, Emad Yahaghi, Afshin Taheriazam, Koroosh Ahmadi
No abstract text is available yet for this article.
November 9, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27826944/retraction-note-to-prognostic-investigations-of-b7-h1-and-b7-h4-expression-levels-as-independent-predictor-markers-of-renal-cell-carcinoma
#11
Hamid Reza Safaei, Ayoob Rostamzadeh, Omid Rahmani, Mohsen Mohammadi, Omar Ghaderi, Hamid Yahaghi, Koroosh Ahmadi
No abstract text is available yet for this article.
November 9, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27826943/retraction-note-to-overexpression-of-interleukins-il-17-and-il-8-with-poor-prognosis-in-colorectal-cancer-induces-metastasis
#12
Mohsen Mohammadi, Maria Kaghazian, Omid Rahmani, Koorosh Ahmadi, Elham Hatami, Katayoun Ziari, Amir Talebreza
No abstract text is available yet for this article.
November 9, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27826942/retraction-note-to-diagnostic-investigations-of-canine-prostatitis-incidence-together-with-benign-prostate-hyperplasia-prostate-malignancies-and-biochemical-recurrence-in-high-risk-prostate-cancer-as-a-model-for-human-study
#13
Radmehr Shafiee, Alireza Shariat, Soheil Khalili, Hamed Zamankhan Malayeri, Aram Mokarizadeh, Ali Anissian, Mohammad Reza Hafezi Ahmadi, Ehsan Hosseini, Mostafa Naderafif, Siamak Mohsenzadeh, Mohammad Hosein Rasoulian, Reza Rezapour, Maryam Pourzaer
No abstract text is available yet for this article.
November 8, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817085/retraction-note-to-canine-transmissible-venereal-tumor-and-seminoma-a-cytohistopathology-and-chemotherapy-study-of-tumors-in-the-growth-phase-and-during-regression-after-chemotherapy
#14
J Javanbakht, B Pedram, M R Taheriyan, F Khadivar, S H Hosseini, F S Abdi, E Hosseini, M Moloudizargari, S H Aghajanshakeri, S Javaherypour, R Shafiee, R Emrani Bidi
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817084/retraction-note-to-improving-the-diagnosis-treatment-and-biology-patterns-of-feline-mammary-intraepithelial-lesions-a-potential-model-for-human-breast-masses-with-evidence-from-epidemiologic-and-cytohistopathologic-studies
#15
Javad Yaghoobi Yeganeh Manesh, Radmehr Shafiee, Behnam Pedram, Hamed Zamankhan Malayeri, Sheida Mohajer, Sharareh Ahmadi, Shirin Ahmadi, Javad Javanbakht, Aram Mokarizadeh, Farshid Khadivar
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817083/retraction-note-to-diagnostic-procedures-for-improving-of-the-kit-cd117-expressed-allele-burden-for-the-liver-metastases-from-uterus-mast-cell-tumors-prognostic-value-of-the-metastatic-pattern-and-tumor-biology
#16
Ehsan Hosseini, Behnam Pedram, Ali Mohammad Bahrami, Seyed Rashid Touni, Hamed Zamankhan Malayeri, Aram Mokarizadeh, Mehdi Pourzaer, Maryam Pourzaer, Shahram Zehtabian, Sheida Mohajer, Sharareh Ahmadi
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817082/retraction-note-to-urinary-parameters-predictive-and-electrolyte-disturbances-of-cisplatin-induced-acute-renal-associated-with-cancer-as-a-critical-target-of-the-chemotherapeutic-agent-in-patients-with-solid-tumors
#17
Behnam Pedram, Ahmad Taghavi Moghadam, Zahra Kamyabi-Moghaddam, Omid Mavedati, Babak Abbas Beigi, Adel Khodaei Sharabiyani, Ali Bashiri Dezfuli, Soheil Khalili, Ali Mohammad Bahrami, Alireza Nasoori
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817081/retraction-note-to-expression-and-prognostic-value-of-the-aldehyde-dehydrogenase-1-aldh1-and-n-myc-downstream-regulated-gene-2-ndrg2-as-potential-markers-in-human-astrocytomas
#18
Peyman Karimi Goudarzi, Farzad Mehrabi, Reza Jalili Khoshnood, Ali Baradaran Bagheri, Koorosh Ahmadi, Emad Yahaghi, Hesam Abdolhoseinpour
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817080/retraction-note-to-tissue-expression-levels-of-mir-29b-and-mir-422a-in-children-adolescents-and-young-adults-age-groups-and-their-association-with-prediction-of-poor-prognosis-in-human-osteosarcoma
#19
Reza Bahador, Afshin Taheriazam, Alireza Mirghasemi, Ali Torkaman, Mohammadreza Shakeri, Emad Yahaghi, Peyman Karimi Goudarzi
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817079/retraction-note-to-downregulation-of-mir-185-and-upregulation-of-mir-218-expression-may-be-potential-diagnostic-and-prognostic-biomarkers-of-human-chondrosarcoma
#20
Peyman Karimi Goudarzi, Afshin Taheriazam, Saeid Asghari, Mohammad Jamshidi, Mohammadreza Shakeri, Emad Yahaghi, Alireza Mirghasemi
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
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