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Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology

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https://www.readbyqxmd.com/read/28795391/uncommon-cause-of-cirrhosis-a-case-of-werner-syndrome-with-a-novel-wrn-mutation
#1
S Deepak Amalnath, Forough Sargolzaeiaval, Junko Oshima, Dipti Baskar
Werner syndrome is a rare progeroid syndrome caused by the WRN gene mutation. It is characterized by a general appearance of premature aging, diabetes mellitus, and atherosclerosis, and an increased risk of malignancies. We report a patient who presented with hematemesis due to cirrhosis of liver and was subsequently diagnosed with Werner syndrome. Further genetic analysis showed a novel mutation in the WRN gene which has not previously been reported. Werner syndrome should be considered for the cases of liver cirrhosis when accompanied by the features of accelerated aging...
August 9, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28782079/lymph-node-micrometastasis-in-gallbladder-cancer
#2
Swati H Shah, Nikhil Gupta, Gurudutt Gupta, Anurag Mehta, Shivendra Singh
BACKGROUND: Prognosis of gallbladder cancer (GBC) is grim even after curative surgery. Lymph node metastasis is the most important prognostic factor, but distant relapses occurring in their absence point towards additional factor. Lymph node micrometastasis could be one. The present study aimed to evaluate the incidence and clinical significance of lymph node micrometastasis. METHODS: This is a prospective study of patients undergoing curative surgery for GBC from 1 March 2013 to 30 April 2015, at our institute...
August 7, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28779276/changes-in-adiposity-and-other-cardiometabolic-risk-factors-following-roux-en-y-gastric-bypass-a-12-month-prospective-cohort-study-in-chinese-patients
#3
Mohsen Mazidi, Hong-Kai Gao, Han Hui, Liang Li, Gordon A Ferns
AIM: We aimed to investigate the changes in adiposity and other cardiometabolic risk factors in the year following Roux-en-Y gastric bypass (RYGB) in patients of Chinese ethnicity. METHODS: The study recruited 209 patients who met the indications for bariatric surgery. Adiposity and cardiometabolic risk factors were assessed at baseline and over the 12 months following surgery in all participants. SPSS® software was used for statistical analysis. RESULTS: The mean body mass index (BMI) was 29...
August 5, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28762140/the-use-of-a-transparent-cap-in-sigmoidoscopy-a-randomized-controlled-clinical-trial-on-pain-time-and-success-rate
#4
Magnus Ploug, Jacob Kvist Poulsen, Henning Quist Jensen, Michael Achiam
Trials on cap-assisted colonoscopy have shown a reduction in pain, faster intubation time and a higher success rate attributed to the use of the cap. No similar studies have been published on sigmoidoscopy even though it is a common procedure associated with significant pain. Our objective was to investigate whether the use of a transparent cap for sigmoidoscopy has an impact on pain, time or success rate. To mimic the tendencies of daily clinical practice, the trainee endoscopist performed the procedures, and no analgesics or sedatives were used...
August 1, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28762139/daclatasvir-sofosbuvir-for-treatment-of-hepatitis-c-virus-in-patients-with-inherited-bleeding-disorders
#5
LETTER
Rajiv Mehta, Mayank Kabrawala, Subhash Nandwani, Pankaj Desai, Vishwa Bhayani, Sanjay Patel, Viral Parekh
No abstract text is available yet for this article.
August 1, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28762138/hrqol-using-sf36-generic-specific-in-liver-cirrhosis
#6
K Janani, Joy Varghese, Mayank Jain, Kavya Harika, Vijaya Srinivasan, Tom Michael, Venkataraman Jayanthi
Health-related quality of life (HRQOL) is influenced by the disease state, associated complications and their management. In patients with liver cirrhosis co-morbidity, severity of liver disease and their complications are likely to affect the QOL. The aim of the study was to determine the factors that are likely to influence the domains of HRQOL using SF-36 in patients with liver cirrhosis. For the study, 149 patients with liver cirrhosis were compared with age-gender matched healthy controls for physical and mental components of SF-36 score and the effects of age, co-morbidity severity of liver disease and complications of liver cirrhosis on HRQOL were assessed using the same questionnaire...
August 1, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28755264/patient-satisfaction-and-safety-profile-with-sedation-during-gastrointestinal-endoscopy
#7
LETTER
Nimesh K Tarway, Mayank Jain, V P Rajavel, Srinivas Melpakkam, Vijaya Srinivasan, R Ravi, Joy Varghese, Tom Michael, Jayanthi Venkataraman
No abstract text is available yet for this article.
July 29, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28752361/the-role-of-preoperative-c-reactive-protein-and-procalcitonin-as-predictors-of-post-pancreaticoduodenectomy-infective-complications-a-prospective-observational-study
#8
Verushka Mansukhani, Gunjan Desai, Rajiv Shah, Palepu Jagannath
INTRODUCTION: The common causes of morbidity after pancreaticoduodenectomy (PD) are infective complications. Till date, no specific preoperative markers have been identified to determine the probability of developing infective complications. We have studied the factors predicting the occurrence of the infective complication/s in the present study. METHODS: The present prospective observational study included 133 consecutive patients who underwent PD from January 2011 to June 2016 at a specialized hepatopancreaticobiliary surgical oncology unit...
July 28, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28744748/biliary-complications-after-living-donor-liver-transplantation-a-retrospective-analysis-of-the-kyoto-experience-1999-2004
#9
Ayman Zaki Azzam, Koichi Tanaka
BACKGROUND AND AIM: In living donor liver transplantation (LDLT), biliary complications continue to be the most frequent cause of morbidity and may contribute to mortality of recipients although there are advances in surgical techniques. This study will evaluate retrospectively the short-term and long-term management of biliary complications. METHODS: During the period from May 1999, to May 2004, 505 patients underwent 518 LDLT in the Department of Liver Transplantation and Immunology, Kyoto University Hospital, Japan...
July 26, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28741237/cytotoxic-t-lymphocytes-and-cd4-epitope-mutations-in-the-pre-core-core-region-of-hepatitis-b-virus-in-chronic-hepatitis-b-carriers-in-northeast-iran
#10
Sareh Zhand, Alijan Tabarraei, Amineh Nazari, Abdolvahab Moradi
BACKGROUNDS: Hepatitis B virus (HBV) is vulnerable to many various mutations. Those within epitopes recognized by sensitized T cells may influence the re-emergence of the virus. This study was designed to investigate the mutation in immune epitope regions of HBV pre-core/core among chronic HBV patients of Golestan province, Northeast Iran. METHODS: In 120 chronic HBV carriers, HBV DNA was extracted from blood plasma samples and PCR was done using specific primers...
July 25, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28741236/awareness-about-celiac-disease-amongst-physicians
#11
LETTER
Sukhman Shergill, Govind K Makharia
No abstract text is available yet for this article.
July 25, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28721508/role-of-preoperative-endoscopy-in-bariatric-surgery
#12
LETTER
Pazhanivel Mohan, Raja Kalayarasan, Santhosh Anand
No abstract text is available yet for this article.
July 19, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28699079/carcinoma-of-gallbladder-clinical-evaluation-and-survival-rate-at-a-tertiary-care-center-in-rajasthan
#13
LETTER
Gopal Goyal, Kumar Shwetanshu Narayan, Gaurav Kumar Gupta, Sandeep Nijhawan
No abstract text is available yet for this article.
July 12, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28681275/obituary-dr-p-muralikrishna-08-14-1963-04-01-2017
#14
A V Siva Prasad
No abstract text is available yet for this article.
July 5, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28674786/fully-covered-self-expanding-metallic-stent-placement-for-benign-refractory-esophageal-strictures
#15
Vinit Kahalekar, Deepak Trilokinath Gupta, Pratin Bhatt, Akash Shukla, Shobna Bhatia
AIMS: Treatment options for benign refractory esophageal stricture are limited. We retrospectively analyzed data of 11 patients who underwent fully covered self-expanding metallic stent (FC-SEMS) placement for refractory benign esophageal stricture at our institute. METHODS: Refractory benign esophageal stricture was defined as inability to dilate a stricture to a diameter of 14 mm after a minimum of five sessions at 2-week intervals or inability to maintain diameter of 14 mm for at least 4 weeks...
May 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28656492/treatment-of-chronic-genotype-3-hepatitis-c-virus-infection-using-direct-acting-antiviral-agents-an-indian-experience
#16
Amit Goel, Rajat Bhargava, Praveer Rai, Rakesh Aggarwal
BACKGROUND: Direct-acting antiviral drugs (DAAs) are favored for the treatment of hepatitis C virus (HCV) infection. However, the experience with the DAAs currently available in India in the treatment of genotype-3 HCV is limited. We therefore reviewed our experience with these drugs in treating patients with chronic genotype-3 HCV infection, including those with cirrhosis. METHODS: We prospectively followed adult patients with genotype-3 HCV infection who had received treatment regimens containing sofosbuvir with/without daclatasvir...
May 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28643273/chronic-constipation-in-rome-iv-era-the-indian-perspective
#17
REVIEW
Uday C Ghoshal
Chronic constipation (CC) is a common problem in the community and in gastroenterology practice all over the world including India. After release of Rome IV guidelines in April 2016, there is increasing interest among gastroenterologists and physicians in India to look into special issues on CC in the Indian perspective. There are important differences in the bowel habit, definition, epidemiology, and pathophysiology including dietary factors and management of CC in India as compared to the West. As severity and frequency of abdominal pain, a symptom essential to diagnose constipation-predominant irritable bowel syndrome (IBS-C) rather than functional constipation (FC), is less common among Indian patients, FC is commoner than IBS-C in India...
May 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28643272/prevalence-and-risk-factors-for-low-bone-mineral-density-in-ulcerative-colitis
#18
Ram Pratap Singh Bundela, Prachis Ashdhir, Kumar Shwetanshu Narayan, Mukesh Jain, Rupesh Kumar Pokharna, Sandeep Nijhawan
BACKGROUND: Inflammatory bowel disease (IBD) has been associated with increased risk of osteopenia and osteoporosis. Several risk factors contribute to this; however, studies evaluating their association have conflicting results. METHODS: We conducted a cross-sectional study with prospective enrollment of adult ulcerative colitis patients attending the Gastroenterology Department of Sawai Man Singh Hospital, Jaipur Rajasthan between June 2015 and December 2015. Demographic data including age, gender, body mass index (BMI), disease duration, type of disease, prior steroid use and vitamin D levels were recorded and compared with bone mineral density (BMD) using dual-energy X-ray absorptiometry (DEXA)...
May 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28631134/budd-chiari-syndrome-outcomes-of-endovascular-intervention-a-single-center-experience
#19
Nitin Jagtap, Mithun Sharma, Jagdeesh Singh, Manu Tandan, P N Rao, Rajesh Gupta, Sundeep Lakhtakia, Mohan Ramchandani, Harshal Shah, T Mahesh Kumar, Santosh Darishetty, G V Rao, D N Reddy
AIM: Outcomes of endovascular intervention in Budd-Chiari syndrome (BCS) have been reported with varied results. Clinical outcomes of endovascular interventions in BCS and role of various prognostic scores were critically evaluated in this study. METHODS: This study retrospectively analyzed consecutive patients of BCS who underwent endovascular intervention between January 2007 and May 2016 at our center. Technical, clinical successes and complications were documented...
May 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28631133/bone-density-in-pediatric-crohn-s-disease-a-cross-sectional-observation-from-south-india
#20
Shiraz Salim Khan, Sagar S Patil
BACKGROUND: Crohn's disease (CD) frequently manifests in the second and third decades of life. Malnutrition and corticosteroid therapy may affect bone mineralization and delay bone growth. Our aim was to study bone mineral density and factors associated low bone mineral density (BMD) in pediatric CD. METHODS: A cross-sectional observational study in children with CD (aged 5 to <18 years) was done. Demographic and treatment details were noted. Vitamin D levels <20 ng/mL were considered as deficiency...
May 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
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