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Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology

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https://www.readbyqxmd.com/read/29987750/risk-factors-for-inflammatory-bowel-disease-a-prospective-multi-center-study
#1
Anjali D Amarapurkar, Deepak N Amarapurkar, Pravin Rathi, Prabha Sawant, Nikhil Patel, Praful Kamani, Krishnakant Rawal, Rajiv Baijal, Ameya Sonawane, Nitin Narawane, Samrat Kolekar, Naveen Totla
INTRODUCTION: Environmental risk factors have been associated with inflammatory bowel disease (IBD). With rising incidence, it is important to know risk factors associated with IBD in our population. This study was aimed to evaluate risk factors for IBD from western India. METHODS: This was prospective, multi-center case-control study which included 1054 patients with IBD of which 765 (72.5%) were ulcerative colitis (UC) and 289 (27.4%) Crohn's disease (CD). Asymptomatic individuals without a history of any major illness served as controls...
July 9, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29984390/raised-plasma-levels-of-h-2-s-and-nitrate-predict-intrapulmonary-vascular-dilations-a-preliminary-report-in-patients-with-cryptogenic-cirrhosis
#2
Chinmay Bera, Kavitha Thangaraj, Purendra Kumar Pati, Jeyamani Ramachandran, K A Balasubramanian, Anup Ramachandran, Uday Zachariah, K G Sajith, Ashish Goel, C E Eapen
BACKGROUND AND AIMS: The role of vasoactive chemicals in the pathogenesis of hepatopulmonary syndrome (HPS), a disorder characterized by intrapulmonary vascular dilation (IPVD), is only vaguely elucidated. We aimed to study the association between plasma H2 S, nitrate levels, and presence and severity of IPVD and HPS. METHODS: Consecutive adult patients with cryptogenic cirrhosis were evaluated for IPVD (by contrast echocardiography) and for hypoxemia (by arterial blood gas analysis)...
July 9, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29971689/endoscopic-ultrasound-guided-thrombin-injection-for-management-of-visceral-artery-pseudoaneurysm-a-novel-approach
#3
Ashok Jhajharia, Shashank Wanjari, Prachis Ashdhir, Deepak Sharma, Rupesh Pokharna, Sandeep Nijhawan
Visceral artery pseudoaneurysm is a rare and potentially life-threatening vascular entity with a high mortality rate, conventionally managed with digital subtraction angiography with coil embolization or surgery. However, in cases where angiographic coil embolization is not possible due to technical reasons, computerized tomography (CT)/ultrasonography-guided thrombin injection remains a viable option as described in the literature. In this case series, we intend to highlight the role of endoscopic ultrasound-guided thrombin injection in the management of abdominal visceral artery pseudoaneurysm, which is either inaccessible by endovascular route or have high surgical risk of complication...
July 4, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29971688/dyssynergic-defecation-the-not-so-hidden-partner-in-constipation
#4
EDITORIAL
Kewin Tien Ho Siah
No abstract text is available yet for this article.
July 4, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29967961/do-additional-colonoscopic-biopsies-increase-the-yield-of-mycobacterium-tuberculosis-culture-in-suspected-ileo-colonic-tuberculosis
#5
Vatsal Mehta, Devendra Desai, Philip Abraham, Tarun Gupta, Camilla Rodrigues, Anand Joshi, Ramesh Deshpande, Prabha Sawant, Mehgraj Ingle, Pravin Rathi, Ameet Mandot
BACKGROUND: Isolation of Mycobacterium tuberculosis on culture is vital for differentiating intestinal tuberculosis (ITB) from Crohn's disease (when histology is not diagnostic) and for diagnosis of multidrug-resistant tuberculosis. The current yield of TB culture (< 50%) from colonoscopic biopsy tissue is not satisfactory. AIM: To determine whether more colonoscopic biopsies can increase the yield of TB culture in patients with ITB. METHODS: In this prospective study, in patients who underwent colonoscopy for suspected ITB, four biopsies were taken (container 1) followed by an additional four biopsies (container 2) for TB culture, from involved regions...
July 3, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29936618/portal-hypertension-and-hypersplenism-in-extrahepatic-portal-venous-obstruction-are-they-related
#6
Ragini Kilambi, Anand Narayan Singh, Kumble Seetharama Madhusudhan, Sujoy Pal, Renu Saxena, Shalimar, Nihar Ranjan Dash, Peush Sahni
BACKGROUND AND AIMS: Portal hypertension (PHT) due to extrahepatic portal venous obstruction (EHPVO) is common in developing countries. Hypersplenism is a near-constant feature of EHPVO, but its significance, unlike in cirrhotics, is unknown. We aimed to study the relationship between hypersplenism and the severity of PHT in patients with EHPVO. METHODS: This prospective study was done at a tertiary care center from January 2014 to August 2015. All patients with EHPVO who underwent a splenectomy and a shunt or devascularization were included...
June 23, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29931479/corticosteroids-nutrition-pentoxifylline-or-fecal-microbiota-transplantation-for-severe-alcoholic-hepatitis
#7
Cyriac Abby Philips, Nikhil Phadke, Karthik Ganesan, Shatakshi Ranade, Philip Augustine
INTRODUCTION: Alcohol-induced intestinal dysbiosis is central to the development of the severe alcoholic liver disease. We present the first study to compare outcomes in patients of severe alcoholic hepatitis (SAH) on nutritional therapy, corticosteroids, pentoxifylline, and healthy donor fecal transplantation (FMT) and discuss distinct microbial community and microbiome metabolic functional changes after FMT. METHODS: Out of 1271 liver disease patients, 809 (63...
June 21, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29922972/prof-badri-nath-tandon-1931-2018
#8
Yogesh Chawla
No abstract text is available yet for this article.
June 20, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29915964/endoscopic-ultrasound-guided-transesophageal-thoracentesis-for-minimal-pleural-effusion
#9
Surinder Singh Rana, Ravi Sharma, Rajesh Gupta
BACKGROUND: Pleural effusion is a common finding both in patients with benign and malignant diseases of pleura and lung with diagnostic thoracentesis establishing the diagnosis in the majority of cases. The diagnostic thoracentesis can be done either blindly or under the guidance of ultrasound or computed tomography. However, minimal pleural effusion is difficult to sample even under image guidance. Endoscopic ultrasound (EUS) is known to detect smaller volume of pleural effusion and, thus, can help in guiding thoracentesis...
June 19, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29948994/comparative-study-of-tinidazole-versus-metronidazole-in-treatment-of-amebic-liver-abscess-a-randomized-control-trial
#10
Sudhakar Pandey, Gaurav Kumar Gupta, Shashank J Wanjari, Sandeep Nijhawan
BACKGROUND: Metronidazole is a drug of choice for amebic liver abscess (ALA), but has long course and significant side effects. Thus, drugs like tinidazole with a better tolerability record need evaluation. METHODS: We conducted a randomized controlled trial at the Department of Gastroenterology, SMS Hospital, Jaipur, India. One hundred and fifty admitted patients were randomized into two treatment groups, metronidazole (group M, n = 75) and tinidazole (group T, n = 75)...
June 14, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29948993/prevalence-of-celiac-disease-among-pediatric-patients-with-cryptogenic-cirrhosis-and-effect-of-gluten-free-diet
#11
Ashish Joshi, Sushil Falodia, Naveen Kumar, Pawan Gupta, P C Khatri
BACKGROUND: Liver involvement in celiac disease (CD) is classified into autoimmune and cryptogenic. The association between CD and autoimmune liver diseases like autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis is well-established; however, the data on patients with cryptogenic cirrhosis, particularly from India, are scanty. So we did this study to find the prevalence of CD in patients with cryptogenic cirrhosis. METHODS: This was a prospective observational study, involving children of less than 18 years old attending Pediatric and Gastroenterology clinic with a diagnosis of cryptogenic cirrhosis...
June 13, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29948992/is-the-emergence-of-inflammatory-bowel-disease-a-prime-example-of-the-third-epidemiological-transition
#12
EDITORIAL
Saurabh Kedia, Vineet Ahuja
No abstract text is available yet for this article.
June 12, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29948991/clinical-predictors-and-gender-wise-variations-in-dyssynergic-defecation-disorders
#13
Mayank Jain, Rajiv Baijal, Melpakkam Srinivas, Jayanthi Venkataraman
BACKGROUND: There is insufficient data from India regarding clinical predictors of dyssynergic defecation. AIM: To identify demography, symptom, and colonoscopic parameters that can predict dyssynergic defecation (DD) among patients with chronic constipation (CC) and to compare the profile among male and female patients with DD. METHODS: Data collected from three centers during June 2014 to May 2017 included age, gender, symptom duration, form and consistency of stools, digital examination, colonoscopy, and anorectal manometry (ARM)...
June 12, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29876742/helicobacter-pylori-is-associated-with-increased-risk-of-serrated-colonic-polyps-analysis-of-serrated-polyp-risk-factors
#14
Anand Kumar, Mimi Kim, Dana J Lukin
BACKGROUND: Sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA) are recognized precursors of colorectal cancer, but their risk factors are not well established. We investigated the association between Helicobacter pylori infection (HPI) and the development of SSA and TSA. METHODS: Retrospective data were collected on patients aged ≥ 18 years that underwent colonoscopy with biopsy between 2006 and 2016. Based on histology, patients were classified into three groups: those with SSA and/or TSA, (serrated neoplasia group, SN); conventional adenomas only (CA); and with no polyps (NP)...
June 7, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29855856/genotyping-of-hepatitis-b-virus-isolates-from-lahaul-and-spiti-district-in-himachal-pradesh-india
#15
Brij Sharma, Harshita Katiyar, Deepesh Barall, Neetu Sharma, Shikha Agnihotry, Amit Goel, Rakesh Aggarwal
Hepatitis B virus (HBV) has several genotypes. In the Indian population, genotypes A and D are the most frequent. HBV infection is hyper-endemic in the Lahaul and Spiti district in Himachal Pradesh; however, the virus genotype in this area is not known. We sequenced a 398-nucleotide segment of HBV genome that included parts of pre-S1/S2 and polymerase genes from 17 specimens from this district, and assigned a viral genotype to these. Of the 17 specimens studied, 13 (76% [95% confidence interval = 50-92%]) showed the presence of genotype C HBV; the remaining four were genotype D (n = 4; 24%) HBV...
June 1, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29855855/vitamin-d-levels-in-ulcerative-colitis-at-first-diagnosis-does-it-bell-the-cat
#16
LETTER
Mayank Jain, Jayanthi Venkataraman
No abstract text is available yet for this article.
June 1, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29744756/regression-of-fibrosis-in-pediatric-liver-diseases
#17
Vikrant Sood, Bikrant Bihari Lal, Archana Rastogi, Rajeev Khanna, Dinesh Rawat, Seema Alam
The concept of irreversibility of cirrhosis has been challenged in the recent past with literature in this regard, albeit still scarce, now being accumulated across all age groups, etiologies, and geographical regions. This small series of nine pediatric cases elegantly recapitulates the concept of regression of hepatic fibrosis/cirrhosis and paves way for further detailed studies to enable development of therapeutic anti-fibrotic modalities in future.
May 9, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29704174/predictors-of-90-day-mortality-in-patients-with-severe-alcoholic-hepatitis-experience-with-183-patients-at-a-tertiary-care-center-from-india
#18
Ravi Daswani, Ashish Kumar, Shrihari Anil Anikhindi, Praveen Sharma, Vikas Singla, Naresh Bansal, Anil Arora
BACKGROUND: Severe alcoholic hepatitis (AH) is not an uncommon indication for hospital admission in India. However, there is limited data from India on predictors of mortality in patients of severe AH. We analyzed the data on patients with severe AH admitted to our institute and compared various parameters and severity scores in predicting 90-day mortality. METHODS: In this prospective study, we analyzed patients with severe AH (defined as discriminant function ≥ 32) admitted from January 2015 to February 2017 to our institute...
March 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29629510/endoscopic-ultrasound-guided-coil-or-glue-injection-in-post-cyanoacrylate-gastric-variceal-re-bleed
#19
Roy J Mukkada, Rajesh Antony, Mathew J Chooracken, Jose V Francis, Antony P Chettupuzha, Pradeep G Mathew, Philip Augustine, Abraham Koshy
BACKGROUND AND AIMS: N-butyl-cyanoacrylate injection is recommended in bleeding/recently bled gastric varices. However, cyanoacrylate injection is associated with re-bleed in 25% to 50% of patients. Endoscopic ultrasound (EUS)-guided coil application is an emerging treatment modality for bleeding gastric varices. The aim of this study was to compare EUS-guided coil application combined with or without cyanoacrylate glue injection to injection alone in post-glue gastric variceal re-bleed...
March 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29619673/pre-endoscopic-retrograde-cholangiopancreatography-ercp-administration-of-rectal-indomethacin-in-unselected-patients-to-reduce-post-ercp-pancreatitis-a-systematic-review-and-meta-analysis
#20
Rajat Garg, Babu P Mohan, Rajesh Krishnamoorthi, Tarun Rustagi
INTRODUCTION: Previous studies have reported that peri-procedural administration of rectal indomethacin reduces the risk of pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Based on these studies, gastrointestinal (GI) societies recommend prophylactic rectal indomethacin for all patients undergoing ERCP. However, recent studies have reported contradictory results. The aim of this study was to perform a systematic review and meta-analysis to estimate the pooled relative risk (RR) of post-ERCP pancreatitis (PEP) in unselected patients who received rectal indomethacin before the ERCP (pre-ERCP) compared to patients who received pre-ERCP rectal placebo...
March 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
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