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Minerva Endocrinologica

Francisca Caimari, Rosa Corcoy, Susan M Webb
Pregnancy in women with a diagnosis of Cushing' syndrome (CS) is an extremely rare event and its diagnosis and treatment are a real medical challenge. During pregnancy, the hypothalamus-pituitary-adrenal axis undergoes major changes leading to a significant increase in plasma cortisol levels throughout gestation. The difficulties in diagnosis are related to the resemblance of symptoms of CS and those of pregnancy, and to the complex interpretation of the screening tests. Moreover, the diagnostic work up in the postnatal period may be difficult in the first weeks postpartum...
February 13, 2018: Minerva Endocrinologica
Raffaele Pezzani
No abstract text is available yet for this article.
February 13, 2018: Minerva Endocrinologica
Vincenzo Nuzzo, Tiziana Attardo, Giuseppe Augello, Davide Brancato, Salvatore Camerlingo, Clelia Canale, Federica Coretti, Alessandro Franco, Francesco Giacometti, Maurizio Gambacorta, Massimo Loreno, Ada Maffettone, Vincenzo Provenzano, Alfonso Zuccoli
Audit is a clinical instrument of government characterized by a whole process of evaluation inter pares to improve medical behaviors in the clinical practice. Different endocrinopathies are underestimated in the clinical and diagnostics practice but they can be a real problem in patients admitted in the departments of Internal Medicine. The Adrenal Incidentaloma (AI) is an accidental discovery with an incidence equal to 4% in radiologic studies but it's rarely considereted in the internal disorders. In the departments of Internal Medicine are hospitalized each year approximately 1...
February 13, 2018: Minerva Endocrinologica
Li Zhang, Guilan Zou
BACKGROUND: To study the application value of thyroid ultrasound combined with thyroglobulin (Tg) in the diagnosis of postoperative recurrence of thyroid cancer, so as to provide a reference for clinical practice. METHODS: 80 patients with thyroid cancer who underwent operative treatment for more than 2 times in our hospital from January 2014 to December 2016 were selected as the objects of study. After operation, residual thyroid tissues were removed via131 iodine (131 I)treatment, the serum Tg and thyroid globulin antibody (TgAb) were detected, and the cervical ultrasound was performed...
February 13, 2018: Minerva Endocrinologica
Wenchen Guo, Hongyan Wang, Qi Liu, Yuchao Yuan, Yanyan Jing, Xiaoju Yang
BACKGROUND: To investigate the relationship of serum iron and ferritin concentrations in early pregnancy with gestational diabetes mellitus (GDM) complicated in pregnant metaphase through detecting the serum iron and ferritin concentrations in early pregnancy of normal pregnant women, so as to provide new ideas for the early detection and prevention of GDM. METHODS: Spontaneously pregnant women with single fetus receiving prenatal routine examination in our hospital from December 2014 to October 2016 were selected...
February 13, 2018: Minerva Endocrinologica
Toshiki Nagasaki, Yuki Nagata, Yosuke Wakita, Shinsuke Yamada, Hitoshi Goto, Yasuo Imanishi, Naoyoshi Onoda, Masanori Emoto, Masaaki Inaba
PURPOSE: Hashimoto's thyroiditis (HT) is highly prevalent in patients with rheumatoid arthritis (RA). The aim is to determine their relation, focusing on matrix metalloproteinase-3 (MMP-3), a marker predicting joint destruction and RA activity. METHODS: Fifty three consecutive RA patients were prospectively separated into two groups on the basis of the presence or absence of HT; those with and without TPO-Ab or Tg-Ab (34.0% and 66.0%, respectively). To estimate the extent of inflammation and destruction of the thyroid gland, heterogeneity index (HI) was determined ultrasonographically...
February 13, 2018: Minerva Endocrinologica
Ayako Ito, Aya Nozaki, Ichiro Horie, Takao Ando, Atsushi Kawakami
BACKGOUND: Patients with central diabetes insipidus (CDI) are known to lose weight because their polydipsia interferes with their nutritional intake. We retrospectively examined weight changes in CDI patients when they switched from nasal to oral desmopressin. METHODS: Twenty-three patients with CDI were included. Weight change was defined as an increase or decrease of more than 3 kg or 3% body weight. As factors contributing to the weight change, we studied the patients' clinical characteristics and quality of life (QOL) scores as determined by our original questionnaire...
February 8, 2018: Minerva Endocrinologica
Zhaoshu Wu, Yue Cao, Xiaoyan Jiang, Min Li, Gang Wang, Yue Yang, Kai Lu
INTRODUCTION: Emerging evidence indicates that C-X-C chemokine receptor type 4(CXCR 4) is a candidate oncogene in several types of human tumors including papillary thyroid carcinoma (PTC). To investigate its expression impact on clinicopathological features, a meta-analysis was performed. EVIDENCE ACQUISITION: A comprehensive search in the PubMed, Embase and The Cochrane Library (up to March 14, 2017) was performed for relevant studies using multiple search strategies...
February 8, 2018: Minerva Endocrinologica
Mauro Cozzolino, Maria E Coccia, Rita Picone, Gianmarco Troiano
BACKGROUND: The aim of our study was to evaluate the quality of semen of a large sample from general healthy population living in Italy, in order to identify possible variables that could influence several parameters of spermiogram. METHODS: We conducted a cross-sectional study from February 2010 to March 2015, collecting semen samples from the general population. Semen analysis was performed according to the WHO guidelines. The collected data were inserted in a database and processed using the software Stata 12...
February 8, 2018: Minerva Endocrinologica
Andrea Glezer, Marcello D Bronstein
Prolactinomas are the most common cause of pathological hyperprolactinemia, leading to central hypogonadism and, therefore, a frequent etiology of infertility. Treatment, usually with dopamine agonist (DA), can reverse hyperprolactinemia and hypogonadism, allowing pregnancy in the majority of cases. Bromocriptine is still the DA of choice for such purpose. Important issues in DA-induced pregnancies include fetal exposition, both malformations and neuropsychological development and tumor size increase. Regarding microprolactinomas and intrasellar macroprolactinomas, DA should be withdraw as soon as pregnancy is confirmed...
December 21, 2017: Minerva Endocrinologica
Margret Ehlers, Stephanie Allelein, Matthias Schott
TSH receptor antibodies (TRAbs) are characteristic indicators for the common autoimmune thyroid disease Graves' disease (GD). In almost all patients stimulating TRAbs are found leading to hyperthyroidism as these antibodies act in an agonistic manner to TSH. Besides stimulating TRAbs, other TRAbs are also frequently found leading to inhibition of TSH receptor signaling (blocking TRAbs) or to the activation of different signaling cascades resulting in e.g. thyrocyte apoptosis (cleavage antibodies). Patients' sera may contain all three types of TRAbs...
December 21, 2017: Minerva Endocrinologica
Jörg Flitsch, Till Burkhardt
New clinical symptoms from pituitary tumors during pregnancy are rare. Either the patient becomes symptomatic from a known lesion prior to conception during pregnancy, or it is a de-novo diagnosis due to acute symptoms. Non-functioning pituitary tumors can be subdivided into non-functioning pituitary adenomas and other pathologies. This review aims at giving a general overview as well as therapeutical considerations, taking into account that no specific recommendations/guidelines are available for this rare clinical problem...
December 21, 2017: Minerva Endocrinologica
Linyi Yang, Chen Chen, Min Li, Lan Qiu, Jiang Shen, Xiaoxuan Bu
No abstract text is available yet for this article.
December 15, 2017: Minerva Endocrinologica
Xiaoxi Liu, Xiaojuan Li, Changhui Li, Chengjun Gong, Songyan Liu, Yan Shi
BACKGROUND: This paper aims to investigate the regulating role of adipokine expression level in body fat distribution of patients with type 2 diabetes mellitus (T2MD) as well as its correlation with metabolic syndrome (MS). METHODS: 140 patients with T2MD admitted in the Endocrinology Department of the First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2017 to July 2017 were selected; their body height and weight were measured to calculate body mass index (BMI); patients with a BMI ≤23...
December 4, 2017: Minerva Endocrinologica
Litong Zhu, Fei Xiong, Tongxia Cui
No abstract text is available yet for this article.
December 4, 2017: Minerva Endocrinologica
Jialin Su, Liting Yang, Weizhong Chen, Lisheng Liu, Yaoming Xue
No abstract text is available yet for this article.
November 28, 2017: Minerva Endocrinologica
Paul R Brezina
No abstract text is available yet for this article.
March 2018: Minerva Endocrinologica
Angela Pezzolla, Serafina Lattarulo, Andrea Madaro, Giovanni Docimo, Emanuela Lacalendola, Francesco Prete, Rinaldo Marzaioli
No abstract text is available yet for this article.
December 2017: Minerva Endocrinologica
Cristina Ogrin
No abstract text is available yet for this article.
December 2017: Minerva Endocrinologica
Jianming Guo, Ying Liu, Zhiwan Cai, Shuwen Zhang, Yongquan Gu
No abstract text is available yet for this article.
December 2017: Minerva Endocrinologica
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