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Minerva Endocrinologica

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https://www.readbyqxmd.com/read/29205013/study-on-regulation-of-adipokines-on-body-fat-distribution-and-its-correlation-with-metabolic-syndrome-in-type-2-diabetes-mellitus
#1
Xiaoxi Liu, Xiaojuan Li, Changhui Li, Chengjun Gong, Songyan Liu, Yan Shi
BACKGROUND: This paper aims to investigate the regulating role of adipokine expression level in body fat distribution of patients with type 2 diabetes mellitus (T2MD) as well as its correlation with metabolic syndrome (MS). METHODS: 140 patients with T2MD admitted in the Endocrinology Department of the First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2017 to July 2017 were selected; their body height and weight were measured to calculate body mass index (BMI); patients with a BMI ≤23...
December 4, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29205012/evaluation-of-the-different-surgical-parathyroidectomieson-secondary-hyperparathyroidism-in-uremia-patients
#2
Litong Zhu, Fei Xiong, Tongxia Cui
No abstract text is available yet for this article.
December 4, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29185643/effects-of-insulin-intervention-on-the-expression-of-ve-cadherin-%C3%AE-catenin-annexin-a2-annexin-a5-and-14-3-3-protein-in-the-placentas-of-patients-with-gestational-diabetes-mellitus
#3
Jialin Su, Liting Yang, Weizhong Chen, Lisheng Liu, Yaoming Xue
No abstract text is available yet for this article.
November 28, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29160052/an-update-on-disorders-of-calcium-phosphate-and-bone
#4
Camilla Schalin-Jäntti
No abstract text is available yet for this article.
November 20, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29160051/irisin-as-a-regulator-of-bone-and-glucose-metabolism-a-narrative-review
#5
Silvia I Briganti, Gianluigi Gaspa, Gaia Tabacco, Anda M Naciu, Roberto Cesareo, Silvia Manfrini, Andrea Palermo
In humans, irisin is produced mainly by skeletal muscle in response to physical activity. It has been demonstrated that irisin plays a pivotal role in inducing fat browning and regulating energy expenditure. New findings from various studies conducted in both animals and humans suggest that irisin can affect bone and glucose metabolism. In particular, irisin is able to increase bone cortical mass by stimulating the osteoblast pathways, and irisin levels are inversely correlated with the incidence of fragility fractures among postmenopausal women affected by osteoporosis...
November 20, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29160050/study-on-clinical-indicators-of-diabetic-retinopathy
#6
Xuehua Jiao, Gengxu Li, Xueyan Yin
No abstract text is available yet for this article.
November 20, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29160049/lower-irisin-levels-in-coronary-artery-disease-a-meta-analysis
#7
Wenwen Guo, Baihui Zhang, Xia Wang
INTRODUCTION: Irisin is a newly discovered myokine, which is involved in energy metabolism and associated with "browning" of the white adipose tissue, obesity, diabetes mellitus and metabolic syndrome. It's still uncertain that whether irisin level is associated with coronary artery disease. The purpose of this study is to explore the relationship between irisin levels and coronary artery disease. EVIDENCE ACQUISITION: A search of PubMed, MEDLINE, Elsevier Science Direct, Springer, Web of Science and China National Knowledge Infrastructure (CNKI) for studies published from 2000 to 2017 was undertaken to identify relevant studies...
November 20, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29125274/pseudohypoparathyroidism
#8
Luisella Cianferotti, Maria L Brandi
The term pseudohypoparathyroidism (PHP) refers to a spectrum of rare disorders of mineral metabolism, characterized by features due to end-organ resistance to PTH. The phenotypes of Albright hereditary osteodystrophy (AHO), originally described as associated to the disease, and progressive osseous heteroplasia, can be associated to the endocrine manifestations of hormonal resistance. Genetic or epigenetic alterations in the complex imprinted GNAS locus, encoding the alpha-subunit of the stimulatory G protein (GSα) and several other transcripts, give rise to the different forms oh PHP, which can be differentiated according to the phenotype, the response to PTH infusion and in vitro assays testing Gsα activity...
November 10, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29125273/expression-and-clinical-significance-of-egf-and-tgf-%C3%AE-in-chronic-pancreatitis-and-pancreatic-cancer
#9
Chengfei Hao, Zhonglian Li, Xibo Zhang, Hongtao Zhang, Haitao Shang, Jianheng Bao, Haibo Wang
BACKGROUND: The purpose of this project was to investigate the expression and clinical significance of Epidermal growth factor (EGF) and the Transforming growth factor-α (TGF-α) in the occurrence and development of chronic pancreatitis and pancreatic cancer. METHODS: We recruited 31 patients with chronic pancreatitis, 42 with pancreatic cancer, and 20 with normal pancreas in our hospital. Chronic pancreatitis, pancreatic cancer, and normal pancreas expressed EGF and TGF-α mRNAs as well as EGF and TGF-α proteins...
November 10, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29125272/the-relationship-between-the-hormone-levels-before-transplantation-and-outcomes-of-hormone-replacement-therapy-frozen-embryo-transfer
#10
Yao-Fang Liu, Fang Wang, Gui-Ying Huang, Xi-Guang Mao
OBJECTIVE: To analyze the relationship between outcomes of hormone replacement therapy-frozen embryo transfer (HRT-FET) and serum estradiol and progesterone levels on the day of endometrial transformation and before transplantation. METHODS: Clinical datas of patients who underwent 426 cycles of FET were retrospectively analyzed and were divided into groups according to estradiol and progesterone levels. Differences in embryo implantation rate and clinical pregnancy rate were compared, and relationship between estradiol levels and outcome of transplantation was analyzed...
November 10, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29105481/different-therapeutic-options-in-patients-with-cushing-s-syndrome-due-to-bilateral-macronodular-adrenal-hyperplasia
#11
Nora M Albiger, Daniela Regazzo, Maurizio Iacobone, Carla Scaroni
Bilateral macronodular adrenal hyperplasia (BMAH) is a relatively rare cause of Cushing's syndrome (CS). In recent years, growing evidence has shown that steroidogenesis is regulated by aberrant G-protein-coupled receptors (GPCR) expression and their ligands, in a significant proportion of patients with BMAH. The screening of patients with overt or subclinical CS demonstrate the frequent expression of several GPCR that opened the option to potential therapeutic applications. Thus, several studies have demonstrated that targeting the involved receptor with specific antagonists, may result in a more or less effective control of cortisol excess...
November 3, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29083134/clinical-endocrinology-and-hormones-quantitation-the-increasing-role-of-mass-spectrometry
#12
Federica D'Aurizio, Marco Cantù
Clinical endocrinology has always had a close relationship with laboratory medicine. In fact, the quantification of hormones is of great importance for diagnosis, treatment, recurrence and patient's prognosis of endocrine disorders. This review dealt with the role of the laboratory in diagnosing endocrine pathologies related to adrenal gland, pituitary, gonads and thyroid. The measurements of the main hormones (17- hydroxyprogesterone, androstenedione, dehydroepiandrosterone sulphate, testosterone, estradiol, cortisol, aldosterone, metanephrines, thyroglobulin and insulin-like-growth factor-1) were described considering analytical characteristics but also some aspects of pre-analytical and post- analytical steps...
October 27, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28990742/autoimmune-endocrine-diseases
#13
Rosaria M Ruggeri, Giuseppe Giuffrida, Alfredo Campennì
The endocrine system is interested by several autoimmune diseases, characterized by different impact and severity, according to the organs involved. Autoimmune thyroid disorders (i.e. Hashimoto's thyroiditis and Graves' disease) and type 1 diabetes mellitus are the most common autoimmune endocrine disorders, while hypophysitis, adrenalitis (90% of cases of primary hypocortisolism or Addison's disease), premature ovarian failure and hypoparathyroidism represent quite rare conditions. Autoimmune endocrine diseases can also coexist in the same individuals and cluster in families...
October 9, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28990741/post-transplant-diabetes-diagnosis-and-management
#14
Brian P Boerner, Vijay Shivaswamy, Eric Wolatz, Jennifer Larsen
Post-transplant diabetes mellitus (PTDM) is common after most types of solid organ transplantation, though the actual incidence is as yet unknown because of the use of different diagnostic criteria. PTDM is the result of individual risk factors as well as risk factors associated with the transplant itself, particularly immunosuppressants. Previously called New Onset Diabetes, in many cases inadequate screening for diabetes before transplant cannot assure that the diabetes is new after transplant. The most recent international consensus guidelines suggest diagnosis should be delayed until the patient is taking maintenance doses of immunosuppressants even if they require treatment in the immediate hospitalization...
October 9, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28949124/diagnosis-and-management-of-zollinger-ellison-syndrome-in-2017
#15
Claudio DE Angelis, Pablo Cortegoso Valdivia, Ludovica Venezia, Mauro Bruno, Rinaldo Pellicano
Zollinger-Ellison Syndrome (ZES) is a clinical syndrome characterized by gastric acid hypersecretion due to the ectopic secretion of gastrin by a gastrinoma, a neuroendocrine tumor (NET) which mostly develops in the duodenum and in the pancreas. This syndrome was first described by Zollinger and Ellison in 1964; if left untreated, ZES can lead to multiple complications mainly due to gastric hypersecretion and some patients can suffer from the complications of an advanced metastatic disease. Although its clinical features are considered typical, the diagnosis of ZES is often challenging for the clinician...
September 25, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28949123/endocrine-and-neuroendocrine-cytopathology
#16
Massimo Bongiovanni, Stefano LA Rosa, Gerasimos P Sykiotis
Cytology is an easily accessible, cost-effective and safe procedure for the initial evaluation of most endocrine/neuroendocrine lesions. Both fine-needle aspiration cytology and exfoliative cytology have shown good sensitivity and specificity in detecting endocrine/neuroendocrine benign proliferations and malignancies. Thanks to its utility for early diagnosis, cytology has contributed to the decline in mortality of endocrine/neuroendocrine neoplasms. The endocrine system comprises different endocrine organs, such as the thyroid, adrenal glands, paraganglia, parathyroid, pancreas, hypothalamus, pituitary gland, ovaries and testes, which can give rise to non-neoplastic, benign and malignant proliferations...
September 25, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28949122/role-of-positron-emission-tomography-in-thyroid-and-neuroendocrine-tumours
#17
Giorgio Treglia, Alexander S Kroiss, Arnoldo Piccardo, Filippo Lococo, Prasanna Santhanam, Alessio Imperiale
BACKGROUND: Positron emission tomography (PET) is an established imaging method in oncology. PET/computed tomography (PET/CT) and PET/magnetic resonance imaging (PET/MRI) are hybrid techniques which combine morphological information obtained by CT and MRI with functional data provided by PET. Several radiotracers evaluating different metabolic pathways or receptor status can be used as PET radiotracers to assess endocrine tumours such as thyroid tumours or neuroendocrine neoplasms (NENs)...
September 25, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28949121/parathyroid-carcinoma-a-clinical-and-genetic-perspective
#18
Filomena Cetani, Elena Pardi, Claudio Marcocci
Parathyroid carcinoma (PC) is a rare neoplasia difficult to diagnose preoperatively. It mainly occurs as a sporadic disease but also as part of familial PHPT. At variance with patients with the benign counterpart, the phenotype of these patients is characterized by a severe primary hyperparathyroidism (PHPT). The clinical features are mostly due to the effects of the excessive secretion of PTH by the functioning tumor and hypercalcemia rather than to the tumor burden. The prognosis is poor and unmanageable hypercalcemia accounts for death in the majority of cases...
September 25, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28914044/how-many-patients-with-tir3-fna-really-have-a-thyroid-neoplasm
#19
Angela Pezzolla, Serafina Lattarulo, Andrea Madaro, Giovanni Docimo, Emanuela Lacalendola, Francesco Prete, Rinaldo Marzaioli
No abstract text is available yet for this article.
December 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28914043/decrease-in-size-and-activity-of-parathyroid-adenoma-after-ultrasound-guided-biopsy
#20
Cristina Ogrin
No abstract text is available yet for this article.
December 2017: Minerva Endocrinologica
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