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Clinics in Dermatology

Vesna Petronic-Rosic
No abstract text is available yet for this article.
May 2018: Clinics in Dermatology
Claudio Conforti, Emanuela Beninanti, Caterina Dianzani
Actinic keratosis (AK) is a very common skin disease caused by chronic sun exposure. AKs have historically been characterized as being "precancerous" or "premalignant." It is true that these lesions do not possess metastatic potential, because they are confined to the epidermis, but it is not accurate to deem them "premalignant." AK qualifies as a malignant neoplasm, because it also fulfills criteria for malignancy in classic pathology, namely, the capability, or potential, to kill by either destruction of tissue locally or by metastasis widely...
May 2018: Clinics in Dermatology
Lindsay P Osborn, Philip R Cohen
The healing process after breast cancer treatment is predominantly focused toward the physical changes to the body that a patient has experienced. Breast reconstructions are considered standard of care after mastectomy, and the nipple and areolar complex is often reconstructed as well, using a combination of skin graft and tattoo. A patient who decided to forego nipple reconstruction and areolar tattooing and instead chooses to apply decorative temporary tattoos to her breast reconstruction is described. Compared with permanent tattoos, these unconventional tattoos allow the patient to change the design to fit her mood...
May 2018: Clinics in Dermatology
Natalie J Atkin
For centuries, patients afflicted with the peripheral nerve damaging disease, leprosy-sometimes referred to as Hansen's Disease-were excluded from society and harshly stigmatized. Such stigmatization often stemmed from the belief that the disease was a punishment by G-d for wrongdoing. Leprosy's origins remain rooted throughout various European countries; however, the disease established its presence in North America around the late 18th century. In particular, major port cities that experienced high volume trade, such as New Orleans, were most susceptible to infection...
May 2018: Clinics in Dermatology
Deeptej Singh, Juliya Fisher, Devorah Shagalov, Aakaash Varma, Daniel M Siegel
The plant and mushroom kingdoms have species used for intoxication, inebriation, or recreation. Some of these species are toxic. Given that many of these plants or substances are illegal and have histories of abuse, much of the research regarding therapeutic application is based on basic science, animal studies, and traditional use. This review examines Cannabis, Euphorbia, Ricinus, Podophyllum, Veratrum, mushrooms, and nightshades, along with resveratrol and cocaine as they relate to dermatology.
May 2018: Clinics in Dermatology
Shenara Musthaq, Anna Mazuy, Jeannette Jakus
The skin supports a delicate ecosystem of microbial elements. Although the skin typically acts as a barrier, these microbes interact with the internal body environment and imbalances from the "healthy" state that have been linked to several dermatologic diseases. Understanding the changes in microbial flora in disease states allows for the potential to treat by restoring equilibrium. With the rising popularity of holistic and natural consumerism, prebiotics, probiotics, symbiotic, and other therapies are under study to find alternative treatments to these skin disorders through manipulation or supplementation of the microbiome...
May 2018: Clinics in Dermatology
P Haines Ely
The gut is the largest lymphoid organ in the body. The human microbiome is composed of trillions of bacteria. The DNA of these bacteria dwarfs the human genome. Diet and ethanol can cause rapid shifts in the number and types of bacteria in the gut. The psoriatic microbiome is similar to that seen in alcoholics; there is a decrease in bacterial diversity and overgrowth of bacteria in the small bowel. Psoriatics often have liver disease and deficiencies in bile acids. Psoriasis is a disease characterized by a leaky gut...
May 2018: Clinics in Dermatology
Lana Rabinovich, Viktoryia Kazlouskaya
Topical sunscreens are the mainstay for protection from ultraviolet (UV) radiation. With skin cancer rates on the rise and great interest in reversing or preventing the effects of photoaging, new molecules with potential to defend against UV damage have received a great deal of attention. Specifically, there is a growing interest in herbal substances that offer protection against the damaging effects of UV rays. Herbal substances may work as adsorbents of the UV rays and antioxidants and potentially have few side effects...
May 2018: Clinics in Dermatology
Amy Huang, Sophie Seité, Tony Adar
Balneotherapy is the treatment of disease by bathing in thermal spring water. This therapy has been used for centuries and remains a popular form of treatment for dermatologic and rheumatologic diseases today. Although the favorable climates of balneotherapy thermal centers have known beneficial effects on psoriasis and atopic dermatitis, the thermal spring waters themselves can also potentially decrease skin inflammation. The addition of phototherapy to balneotherapy, or balneophototherapy, further enhances the anti-inflammatory effects of thermal spring water...
May 2018: Clinics in Dermatology
Ncoza C Dlova, Moses A Ollengo
More than 80% of the global population depends on traditional medicine for their basic primary health care needs. Africa has a well-established history of botanicals use. These include a vast array of compounds that can be used to treat various skin-related conditions. The rationale for the use of traditional medicine in skincare stems from the physical effects these compounds have on skin, such as the ability to control bleeding and speed up wound healing, as well as the potential to treat burns and other disorders of pigmentation...
May 2018: Clinics in Dermatology
Marilena Gilca, George Sorin Tiplica, Carmen Maria Salavastru
The geographic and ecologic specificity of Romania and other Eastern European countries has resulted in the development of an exceptional diversity of medicinal plants. The purpose of this study was to provide an overview of the ethnobotanical dermatology practices based on the use of medicinal plants in this region. The indications, ethnopharmacologic activities, parts used, and administration of 106 medicinal plants are provided. We also discuss the relative importance of these species, using two modified indices of quantitative ethnobotany: Use Value Index and Relative Dermatologic Importance, which were calculated on the basis of etic constructions (indications and ethnopharmacologic activities)...
May 2018: Clinics in Dermatology
Olga Y Olisova, Elena S Snarskaya, Victor V Gladko, Ekaterina P Burova
The use of herbal remedies for various medical issues is becoming increasingly commonplace in all fields of medicine, and dermatology is no exception. This review focuses on traditional dermatologic herbal remedies, commonly used in Russia, as the rich array of 11 different plant zones has resulted in a great variety of medicinal plants. Herbal remedies warrant deeper investigation and research, especially due to their active substance content, which may interfere with or reinforce the effect of modern medications, something that medical professionals should be aware of when prescribing treatments...
May 2018: Clinics in Dermatology
Myat Sanda Kyaw, Min Min Aye, Madison Grinnell, Morgan Rabach
Skin maladies affect populations worldwide and can have a vast range of clinical manifestations, signs, and complications, including infection, pain, or even stigma for sufferers due to their visibility. Both modern health infrastructure and indigenous systems offer solutions for patients. This contribution provides an overview of the dermatologic uses for Thanatka, a plant that is used topically in Myanmar to treat a myriad of skin diseases. Indigenous to Myanmar, the trees used to produce Thanatka are also present in India, Sri Lanka, Java, and Pakistan...
May 2018: Clinics in Dermatology
Inayat Ur Rahman, Aftab Afzal, Zafar Iqbal, Farhana Ijaz, Niaz Ali, Rainer W Bussmann
In spite of the remarkable achievements in the health care sector over recent decades, inequities in accessibility and affordability of these facilities coexist throughout Pakistan, which has led us to explore and document the cultural knowledge of medicinal plants used in skin disorders by the local community members of Manoor Valley, Pakistan. Field investigations were undertaken during the summer seasons of 2015-2017, and cultural practices of medicinal plants usage for treating various ailments were gathered through interviews with the local inhabitants...
May 2018: Clinics in Dermatology
Reena Rupani, Afton Chavez
Traditional medicine uses cultural knowledge and practices to promote health maintenance as well as diagnose and treat disease. In developing countries, the majority of people rely on traditional medicines; however, many of these practices have not been rigorously and systematically studied or reported. We review the current understanding and research behind traditional therapies prevalent in the Indian subcontinent, including mind-body and energy-based healing, botanical medicine, and herbal remedies. Topics covered include Ayurveda, yoga, naturopathy, Unani, Siddha, Sowa-Rigpa, homeopathy, and medicinal plants such as neem, guggul, tulsi, amla, and turmeric...
May 2018: Clinics in Dermatology
Warren J Winkelman
Complementary and alternative medicine approaches are popular among some patient segments due to the perception that they are "natural" and thus are believed to be less likely to be dangerous, to be less toxic, or to cause fewer side effects. In dermatology, these can include aromatherapy, botanicals, and essential oils (plant extracts). Preliminary evidence, biological activity studies, and small pilot clinical trials conducted outside of North America, mostly in young adults, suggest that some may have value in acne treatment...
May 2018: Clinics in Dermatology
Carl R Thornfeldt
Mucocutaneous diseases and conditions, including aging, are known to be the result of multiple pathophysiologic anomalies induced by various environmental insults. Creating therapeutic products for these multifactorial diseases and conditions is challenging. Although safety testing is not required for cosmetics and cosmeceuticals, consumer expectation is for products to be effective and well tolerated while maintaining cosmetic elegance. This requires that the finished product being sold to consumers should be tested in human clinical trials for safety profile, efficacy, and scientific integrity...
May 2018: Clinics in Dermatology
Robin A C Graham-Brown, Mark F Healsmith
The use of medicinal plants is as old as the hills (and valleys and plains) where they grow. In this brief review, we have set out to emphasize the need for rigor in the assessment of any medicines-whatever their source-as we seek to translate apparently important observations on the efficacy of plant concoctions into real-time clinical practice for the benefit of our fellow men and women. We shall use examples of recently studied compounds that have touched the world of dermatology to illustrate some of the pitfalls and also to draw attention to some of the successes in moving from "folklore to pharmacy...
May 2018: Clinics in Dermatology
Jeannette Jakus, Daniel M Siegel
No abstract text is available yet for this article.
May 2018: Clinics in Dermatology
Eleonora Ruocco, Ronni Wolf, Stefano Caccavale, Gabriella Brancaccio, Vincenzo Ruocco, Ada Lo Schiavo
No abstract text is available yet for this article.
March 2018: Clinics in Dermatology
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